Bibliografias temáticas / B.C-449 A.D

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Literatura científica selecionada sobre o tema "B.C-449 A.D"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 1 de agosto de 2024

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Artigos de revistas sobre o assunto "B.C-449 A.D"

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White, M. B., C. J. Word, C. G. Humphries, F. R. Blattner e P. W. Tucker. "Immunoglobulin D switching can occur through homologous recombination in human B cells". Molecular and Cellular Biology 10, n.º 7 (julho de 1990): 3690–99. http://dx.doi.org/10.1128/mcb.10.7.3690-3699.1990.

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Prototypical class switching in mouse and human immunoglobulin heavy chains occurs through recombination of tandem blocks of short repeats located 5' to each heavy chain constant region (CH) except C delta. Deletion of C mu in immunoglobulin D (IgD)-secreting murine plasmacytomas occurs illegitimately. We demonstrate here that in human IgD-secreting myeloma cells freshly isolated from patient bone marrow and in normal peripheral blood B lymphocytes, an IgD switch can occur through homologous recombination of a direct repeat consisting of a 442-bp sequence 1.5 kbp 3' of the JH complex and a 443-bp sequence that is duplicated almost perfectly (96% similarity) 1.7 kbp 5' of the C delta gene (442/443-base-pair [bp] repeat). This homologous recombination mechanism is not exclusive for IgD switching, since C mu deletion endpoints in two established IgD-secreting myeloma cell lines fall outside the 442/443-bp repeat. The 442/443-bp mediated recombination shows cell type specificity, and we propose that it represents a unique mode for increased levels of IgD secretion in humans.
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White, M. B., C. J. Word, C. G. Humphries, F. R. Blattner e P. W. Tucker. "Immunoglobulin D switching can occur through homologous recombination in human B cells." Molecular and Cellular Biology 10, n.º 7 (julho de 1990): 3690–99. http://dx.doi.org/10.1128/mcb.10.7.3690.

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Prototypical class switching in mouse and human immunoglobulin heavy chains occurs through recombination of tandem blocks of short repeats located 5' to each heavy chain constant region (CH) except C delta. Deletion of C mu in immunoglobulin D (IgD)-secreting murine plasmacytomas occurs illegitimately. We demonstrate here that in human IgD-secreting myeloma cells freshly isolated from patient bone marrow and in normal peripheral blood B lymphocytes, an IgD switch can occur through homologous recombination of a direct repeat consisting of a 442-bp sequence 1.5 kbp 3' of the JH complex and a 443-bp sequence that is duplicated almost perfectly (96% similarity) 1.7 kbp 5' of the C delta gene (442/443-base-pair [bp] repeat). This homologous recombination mechanism is not exclusive for IgD switching, since C mu deletion endpoints in two established IgD-secreting myeloma cell lines fall outside the 442/443-bp repeat. The 442/443-bp mediated recombination shows cell type specificity, and we propose that it represents a unique mode for increased levels of IgD secretion in humans.
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Fouad, Farid, Scott D. Bunge, Brett D. Ellman e Robert J. Twieg. "Tetranaphthyleno[5,6-bcd:11,12-b′c′d′:17,18-b′′c′′d′′:23,24-b′′′c′′′d′′′]tetrafuran". Acta Crystallographica Section C Crystal Structure Communications 68, n.º 11 (20 de outubro de 2012): o465—o467. http://dx.doi.org/10.1107/s0108270112040681.

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The title compound, C40H16O4or [C10H4O]4, is a planar tetrameric cyclooligomer which crystallizes in the monoclinic space groupP21/n. The compound is located on an inversion center with the asymmetric unit consisting of half of the molecule. The compound displays an interesting packing structure, where the cyclooligomer displays both layered packing with respect to nearest neighbors and a rotation of adjacent planar rings that results in additional interactions. The geometric parameters of the compound agree well with those of comparable cyclooligomers, while the packing reveals some similarities and differences.
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Houtekamer, P. L., e Fuqing Zhang. "Review of the Ensemble Kalman Filter for Atmospheric Data Assimilation". Monthly Weather Review 144, n.º 12 (1 de novembro de 2016): 4489–532. http://dx.doi.org/10.1175/mwr-d-15-0440.1.

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Abstract This paper reviews the development of the ensemble Kalman filter (EnKF) for atmospheric data assimilation. Particular attention is devoted to recent advances and current challenges. The distinguishing properties of three well-established variations of the EnKF algorithm are first discussed. Given the limited size of the ensemble and the unavoidable existence of errors whose origin is unknown (i.e., system error), various approaches to localizing the impact of observations and to accounting for these errors have been proposed. However, challenges remain; for example, with regard to localization of multiscale phenomena (both in time and space). For the EnKF in general, but higher-resolution applications in particular, it is desirable to use a short assimilation window. This motivates a focus on approaches for maintaining balance during the EnKF update. Also discussed are limited-area EnKF systems, in particular with regard to the assimilation of radar data and applications to tracking severe storms and tropical cyclones. It seems that relatively less attention has been paid to optimizing EnKF assimilation of satellite radiance observations, the growing volume of which has been instrumental in improving global weather predictions. There is also a tendency at various centers to investigate and implement hybrid systems that take advantage of both the ensemble and the variational data assimilation approaches; this poses additional challenges and it is not clear how it will evolve. It is concluded that, despite more than 10 years of operational experience, there are still many unresolved issues that could benefit from further research. Contents Introduction...4490 Popular flavors of the EnKF algorithm...4491 General description...4491 Stochastic and deterministic filters...4492 The stochastic filter...4492 The deterministic filter...4492 Sequential or local filters...4493 Sequential ensemble Kalman filters...4493 The local ensemble transform Kalman filter...4494 Extended state vector...4494 Issues for the development of algorithms...4495 Use of small ensembles...4495 Monte Carlo methods...4495 Validation of reliability...4497 Use of group filters with no inbreeding...4498 Sampling error due to limited ensemble size: The rank problem...4498 Covariance localization...4499 Localization in the sequential filter...4499 Localization in the LETKF...4499 Issues with localization...4500 Summary...4501 Methods to increase ensemble spread...4501 Covariance inflation...4501 Additive inflation...4501 Multiplicative inflation...4502 Relaxation to prior ensemble information...4502 Issues with inflation...4503 Diffusion and truncation...4503 Error in physical parameterizations...4504 Physical tendency perturbations...4504 Multimodel, multiphysics, and multiparameter approaches...4505 Future directions...4505 Realism of error sources...4506 Balance and length of the assimilation window...4506 The need for balancing methods...4506 Time-filtering methods...4506 Toward shorter assimilation windows...4507 Reduction of sources of imbalance...4507 Regional data assimilation...4508 Boundary conditions and consistency across multiple domains...4509 Initialization of the starting ensemble...4510 Preprocessing steps for radar observations...4510 Use of radar observations for convective-scale analyses...4511 Use of radar observations for tropical cyclone analyses...4511 Other issues with respect to LAM data assimilation...4511 The assimilation of satellite observations...4512 Covariance localization...4512 Data density...4513 Bias-correction procedures...4513 Impact of covariance cycling...4514 Assumptions regarding observational error...4514 Recommendations regarding satellite observations...4515 Computational aspects...4515 Parameters with an impact on quality...4515 Overview of current parallel algorithms...4516 Evolution of computer architecture...4516 Practical issues...4517 Approaching the gray zone...4518 Summary...4518 Hybrids with variational and EnKF components...4519 Hybrid background error covariances...4519 E4DVar with the α control variable...4519 Not using linearized models with 4DEnVar...4520 The hybrid gain algorithm...4521 Open issues and recommendations...4521 Summary and discussion...4521 Stochastic or deterministic filters...4522 The nature of system error...4522 Going beyond the synoptic scales...4522 Satellite observations...4523 Hybrid systems...4523 Future of the EnKF...4523 APPENDIX A...4524 Types of Filter Divergence...4524 Classical filter divergence...4524 Catastrophic filter divergence...4524 APPENDIX B...4524 Systems Available for Download...4524 References...4525
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Sun, Junfeng, Yueling Yang, Qingxia Li, Haiyan Li, Qin Chang e Jinshu Huang. "The ϒ( nS )→ B c D s , B c D d decays with perturbative QCD approach". Physics Letters B 752 (janeiro de 2016): 322–28. http://dx.doi.org/10.1016/j.physletb.2015.11.053.

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Ferrada, Paula, Poornima Vanguri, Rahul J. Anand, James Whelan, Therese Duane, Michel Aboutanos, Ajai Malhotra e Rao Ivatury. "A, B, C, D, echo". Journal of Trauma and Acute Care Surgery 74, n.º 1 (janeiro de 2013): 220–23. http://dx.doi.org/10.1097/ta.0b013e318278918a.

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SOKARI, TOKUBIYE G., e SAUL O. ANOZIE. "Occurrence of Enterotoxin Producing Strains of Staphylococcus aureus in Meat and Related Samples from Traditional Markets in Nigeria". Journal of Food Protection 53, n.º 12 (1 de dezembro de 1990): 1069–70. http://dx.doi.org/10.4315/0362-028x-53.12.1069.

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Coagulase-positive Staphylococcus aureus were isolated from 449 (84.7%) of 530 meat and related samples obtained from traditional markets in Nigeria. All 100 fresh beef and associated 40 wash water and 40 drip water samples examined yielded coagulase-positive S. aureus compared with 258 (86%) of 300 Suya and 61 (61%) of 100 fried beef samples. Of the 449 coagulase-positive strains of S. aureus, 243 (54.1%) elaborated various enterotoxins. Suya (condiment - coated thin slices of skewered beef roasted over wood or charcoal flame) and fried beef yielded the highest proportions of enterotoxin producing strains of 59.3% and 58%, respectively. Relatively lower proportions of strains from fresh beef (52%) and water associated with fresh beef (45%) produced enterotoxin. Most of the organisms tested (139/57.2%) synthesized enterotoxin A (SEA). A few, 37 (15.2%), produced enterotoxin B (SEB), with fewer still producing enterotoxins D (SED, 6.2%) and C (SEC, 5.3%). It is suggested that the high level of contamination with S. aureus of the samples examined resulted from cross contamination, reflecting excessive hand contact with the foodstuffs.
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Schwartzberg, Lee S., Barry V. Fortner e Arthur C. Houts. "Clinical Significance of Symptom Burden and Quality of Life Decrement in Cancer Patients with Mild Anemia." Blood 104, n.º 11 (16 de novembro de 2004): 5305. http://dx.doi.org/10.1182/blood.v104.11.5305.5305.

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Abstract Background. Cancer related anemia (CRA) is associated with increased symptom burden and reduced quality of life (QoL) compared to non-anemic subjects. Standard treatment guidelines for CRA recomend treatment when hemoglobin (Hb) declines to ≤ 10 g/dl. We compared patients with mild anemia to those with normal Hb level to assess clinical significance of mild anemia. Methods. 3416 patients from a large community oncology database sorted by gender and Hb were retrospectively reviewed. Patients receiving chemotherapy (<30 days) and/or growth factor (< 60 days) were excluded. Each case provided one Hb determination and same day self reported scores on the Cancer Care Monitor (CCM), a validated measure of symptom burden, functioning, and health related QoL comprising 6 scales. All CCM items are rated for symptom severity on a 0–10 scale. Effect sizes for male groups are calculated relative to normal males (Hb > 14), and effect sizes for females are calculated relative to normal females (Hb > 12). Positive effect size (Cohen’s exact d) values indicate greater symptom burden, and negative effect size values indicate lower quality of life. Results. Group differences on CCM measures were not accounted for by demographic, cancer diagnosis, and chemotherapy history differences. Table 1 shows a pattern of greater symptom burden, lower functioning, and worse QOL for males and females with mild anemia (p < .05). As compared to standards for minimal clinically important differences such as found with SF-36 (0.09 < Cohen’s d < 0.28). patients with mild anemia showed clinically significant differences in terms of effect size (0.11 < Cohen’s d < 0.61). Conclusions. The QoL impact of mild CRA is significant and failure to treat mild anemia may result in unnecessary symptom burden and noteworthy decrements in health related quality of life. Differences in QoL for Patients with Mild Anemia M Hb12<14 M Hb >14 Effect Size F Hb 10<12 F Hb >12 Effect Size Cancer Care Monitor Measure* (n = 327) (n = 471) Males (n = 449) (n = 2169) Females Note. *Mean (SE) for each item or scale. Adjusted means with different subscripts across rows are significantly different (p < .05) by Bryant Paulson comparisons. Fatigue Item 3.10 (0.16) b 2.27 (0.13) c 0.30 3.47 (0.13) b 2.65 (0.06) d 0.30 Physical Symptoms 49.54 (0.58) b 45.49 (0.48) c 0.38 49.32 (0.49) b 46.97 (0.22) d 0.22 General Distress 49.51 (0.57) b 47.07 (0.47) d 0.19 51.23 (0.49) c 49.85 (0.22) b 0.11 Despair 50.74 (0.52) b 48.58 (0.43) c 0.25 50.37 (0.44) b 49.13 (0.19) c 0.14 Impaired Performance 55.55 (0.87) b 49.78 (0.70) c 0.61 55.02 (0.73) b 49.90 (0.32) c 0.48 Quality of Life 49.41 (0.79) b 53.46 (0.64) c −0.45 48.95 (0.67) b 52.39 (0.29) c −0.35
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Tennant, Forest. "Hepatitis C, B, D, and A". Journal of Addictive Diseases 20, n.º 1 (14 de março de 2001): 9–17. http://dx.doi.org/10.1300/j069v20n01_02.

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Santos, I. C., M. Almeida, J. Morgado, M. T. Duarte e L. Alcácer. "Perylo[1,12-b,c,d]thiophene". Acta Crystallographica Section C Crystal Structure Communications 53, n.º 11 (15 de novembro de 1997): 1640–42. http://dx.doi.org/10.1107/s0108270197007907.

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Teses / dissertações sobre o assunto "B.C-449 A.D"

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Chovanec, Peter. "Studies of B cell development and V(D)J recombination". Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/288271.

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The process of generating the vast diversity of immunoglobulin receptors and secreted antibodies begins with the recombination of the joining (JH), diversity (DH) and variable (VH) genes in the immunoglobulin heavy chain locus. The ability to produce antibodies is restricted to the B cell lineage and is tightly regulated, starting with the temporal separation of the recombination process, in which DH-JH precedes VH-DHJH recombination. Successful recombination of both heavy and light chain loci results in the expression of an antigen receptor on the cell surface. Subsequent selection stages remove non‑functional and autoreactivity receptors from the final pool of antigen responding B cells that ultimately give rise to antibody secreting plasma cells. Understanding the complexity of the recombination processes and the diversity of the resulting antibody repertoire has been a major focus of academic and industrial research alike. Therapeutic monoclonal antibodies have seen many successful applications within the clinic and they constitute a billion-dollar industry. However, limitations therein have resulted in the emergence of antibody engineering approaches and the use of natural sources of alternative heavy chain only antibodies (HCAbs/nanobodies). The biotechnology company Crescendo Biologics has taken the highly desired characteristics of HCAbs a step further with the creation of a mouse platform capable of producing fully humanized HCAbs. The Crescendo platform presents a unique opportunity to expand our understanding of how mouse B cell development functions by exploiting the features of heavy chain only antibody production. Furthermore, the platform enables the expansion of our limited knowledge of the epigenetic mechanisms involved in the recombination of the human immunoglobulin heavy chain locus. Using flow cytometry, with dimensionality reduction analysis approaches, I investigated B cell development in the context of HCAbs. These studies revealed a previously uncharacterised developmentally intermediate B cell population. Due to ethical and availability limitations to studies of human bone marrow, the primary pre-selection human B cell repertoire has not been studied in detail. The isolation of several B cell developmental stages and the use of our novel DNA-based high-throughput unbiased repertoire quantification technique, VDJ-seq, allowed me to study recombination of the human IGH locus sequence and observe HCAb repertoire selection within the mouse environment. The adaptation of next generation sequencing techniques to antigen receptor repertoire quantification has provided an unprecedented insight into repertoire diversity and the alterations it undergoes during infection or ageing. Our VDJ-seq assay is unique in its ability to interrogate DNA recombinants. To expand its capabilities, I investigated several limitations of the technique, including mispriming and PCR/sequencing errors, and implemented experimental and bioinformatics solutions to overcome them, which included the creation of a comprehensive analysis workflow. Finally, I have developed and applied a novel network visualisation method for genome-wide promoter interaction data generated by promoter capture Hi-C. The availability of high quality human pluripotent stem cell datasets allowed me to utilise the new techniques to further our understanding of the dynamics of genome organisation during early human embryonic development. This visualisation approach will be directly applicable to understanding B cell development.
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Kapp, Felix, e Hermann Körndle. "Was lerne ich aus einer Lernaufgabe? a) gar nichts, b) Faktenwissen, c) etwas über meine Lernstrategien, d) Antwort b und c sind richtig". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-76302.

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Interaktive Lernaufgaben stellen eine Möglichkeit dar, das Lernen und den Lernerfolg mit digitalisierten Lehrmaterialien durch interaktive Elemente zu unterstützen. In einer Vielzahl von Learning-Management-Systemen gehört die technische Möglichkeit solche Aufgaben zu erstellen bereits zum Standard-Repertoire. Dieser Beitrag thematisiert anhand von drei empirischen Studien, welchen psychologischen Kriterien interaktive Lernaufgaben genügen sollten, um einen erfolgreichen Wissenserwerb zu fördern. Dabei wird aufgezeigt, dass Lernaufgaben, die unter Beachtung psychologischer Konstruktionsregeln erzeugt wurden, die Lernenden nicht nur beim Erwerb von Faktenwissen unterstützen, sondern ihnen beim selbstregulierten Lernen auch Rückmeldung über die von ihnen eingesetzten und einzusetzenden Lernstrategien geben.
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AZZI, LYAMINE. "Regulation du cycle cellulaire : interaction entre p9#c#k#s#h#s#2 et p34#c#d#c#2. caracterisation de la p15#c#d#k#-#b#p, une nouvelle proteine interagissant avec p34#c#d#k#4 et p33#c#d#k#5". Rennes 1, 1994. http://www.theses.fr/1994REN10063.

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Le cycle cellulaire est constitue de deux phases majeures, la phase s (replication de l'adn) et la phase m (division cellulaire). Celles-ci sont separees par deux periodes gap(g1 and g2). Le cycle cellulaire est hautement regule par les kinases cycline-dependantes (les cdk). La transition g2/m est declenchee par un facteur universel, le mpf m-phase promoting factor, identifie comme un complexe constitue d'au moins deux sous-unites, la p34#c#d#c#2 et la cycline b#c#d#c#1#3. L'entree de la cellule en phase m est caracterisee par une activation de la kinase cdc2 suite a une dephosphorylation sur les residus thr14 et tyr15. Cette dephosphorylation est catalysee par la phosphatase cdc25. Parmi les proteines regulant la formation et l'activation du complexe p34#c#d#c#2/cycline b, la p13#s#u#c#1/p9#c#k#s#h#s semble jouer un role fondamental. La p9#c#k#s#h#s interagit avec la p34#c#d#c#2 a travers deux sites cooperatifs conduisants a la formation d'un complexe p9#c#k#s#h#s/p34#c#d#c#2 tres stable. In vitro, la p9#c#k#s#h#s peut s'assembler en une structure hexamerique impliquant une possible oligomerisation de la p34#c#d#c#2 in vivo. Nous avons purifie une proteine de 15 kda, la p15#c#d#k#-#b#p, qui interagit fortement avec les kinases cdk4/cycline d (impliquee en g1) et cdk5/p25 (preferentiellement exprimee dans les tissus nerveux). La p15cdk-bp retient une kinase active envers les proteines chromosomales hmg i/y et p1 et la mbp myelin basic protein. Immobilisee sur des billes de sepharose, la p15#c#d#k#-#b#p peut constituer un outil important pour etudier la regulation du cycle cellulaire ainsi que la fonction et la pathologie du cerveau
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廖葉媚 e Yip-mei Liu. "Sero-prevalence of hepatitis A, B, C and D viruses in Hong Kong". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31970710.

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Liu, Yip-mei. "Sero-prevalence of hepatitis A, B, C and D viruses in Hong Kong". Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25176535.

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Kratzsch, Axel [Verfasser]. "Entwicklung von magnetron-gesputterten B-C-N-Schichten / Axel Kratzsch". Karlsruhe : KIT-Bibliothek, 1999. http://d-nb.info/1198223448/34.

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Vogel, Matthias [Verfasser], e Ralf [Akademischer Betreuer] Wagner. "Untersuchungen zum Cross Priming Potential der HIV Vakzinekandidaten EHV-C/B und NYVAC-C/B auf über Monozyten generierten dendritischen Zellen / Matthias Vogel. Betreuer: Ralf Wagner". Regensburg : Universitätsbibliothek Regensburg, 2013. http://d-nb.info/1046721674/34.

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Jäschke, Thomas [Verfasser]. "Hochtemperaturstabile Si/B/N/C-Keramiken aus neuen Einkomponentenvorläufern / Thomas Jäschke". Aachen : Shaker, 2003. http://d-nb.info/1172611521/34.

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Naciuk, Fabrício Fredo 1976. "5,8-Dimetoxisoquinolina como intermediário sintético versátil : síntese total das caulibugulonas A, B, C e D e da isoelipticina". [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249044.

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Orientador: Paulo Cesar Muniz de Lacerda Miranda
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química
Made available in DSpace on 2018-08-26T08:46:40Z (GMT). No. of bitstreams: 1 Naciuk_FabricioFredo_D.pdf: 5766349 bytes, checksum: f8a483081babf6f2f69d11fe85cf43ec (MD5) Previous issue date: 2014
Resumo: No presente trabalho, foi estudada a preparação da 5,8-dimetoxisoquinolina através de um expediente baseado na reação de Pomeranz-Fritsh. Na etapa de ciclização deste protocolo foi empregada a N-(2,5-dimetoxibenzil)-2,2-dimetoxietanamina, além de seus dois derivados com o nitrogênio protegido (grupo tosila ou nosila). O núcleo isoquinolíco foi preparado em quatro etapas, a partir de matérias comercialmente disponíveis, com 90% de rendimento. Posteriormente, a 5,8-dimetoxisoquinolina foi submetida à desproteção oxidativa, mediada por NBS ou ácidos trialoisocianúricos, seguida de uma etapa de aminação/oxidação. Assim, quatro produtos naturais foram preparados: as caulibugulonas A e D em cinco etapas e com rendimentos globais de 50% e 26% respectivamente e as caulibugulonas B e C em seis etapas com rendimentos globais de 31% e 61% respectivamente. Ainda, baseado nos estudos de obtenção das caulibugulonas A-D, foi possível preparar dois intermediários sintéticos, a 6-cloro-7-(fenilamino)isoquinolino-5,8-diona e a 7-(fenilamino)isoquinolino-5,8-diona) com rendimentos de 79% (duas etapas) e 45% (one-pot), respectivamente, a partir da isoquinolina. Na sequência, através de ciclização intramolecular promovida por fonte de paládio, a 5H-pirido[3,4-b]carbazol-5,11(10H)-diona foi preparada com 65% de rendimento a partir da 7-(fenilamino)isoquinolino-5,8-diona (via ativação C-H) ou com 50% de rendimento a partir da 6-cloro-7-(fenilamino)isoquinolino-5,8-diona (via arilação direta). Assim, após reações de metilação/redução, a isoelipticina foi preparada com 18% de rendimento global em nove etapas
Abstract: In the present work, the preparation of 5,8-dimethoxyisoquinoline was studied through an expedient based on the reaction of Pomeranz-Fritsh. In the cyclization step of this protocol was applied to N-(2,5-dimethoxy)-2,2-dimethoxyethanamine in addition to their two derivatives with protected nitrogen (nosyl or tosyl group). The isoquinolic core was prepared in four steps from commercially available materials, with 90% yield. Later 5,8-dimethoxyisoquinoline, was subjected to oxidative deprotection, mediated by NBS or trihaloisocyanuric acids, followed by one amination/oxidation step. Thus, the four natural products have been prepared: caulibugulones A and D in five steps and 50% and 26%, overall yield, respectively, and caulibugulones B and C in six steps with overall yields of 31% and 61% respectively. Also, based on studies by obtaining the caulibugulones A-D, it was possible to prepare two synthetic intermediates: 6-chloro-7-(phenylamino)-isoquinoline-5,8-dione and 7-(phenylamino)-isoquinoline-5,8-dione with 79% (two steps) and 45% (one-pot) yield, respectively, from the isoquinoline. Following, through intramolecular cyclization promoted by a source of palladium, 5H-pyrido[3,4-b]carbazole-5,11(10H)-dione was prepared in 65% yield from 7-(phenylamino)isoquinoline-5,8-dione (via C-H activation) or 50% yield from 6-chloro-7-(phenylamino)-isoquinoline-5,8-dione (via direct arylation). Thus, after methylation/reduction reactions, isoellipticine was prepared in 18% overall yield in nine steps
Doutorado
Quimica Organica
Doutor em Ciências
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Peters, Nina [Verfasser], Anja C. [Akademischer Betreuer] Pickhard, Peter B. [Gutachter] Luppa e Anja C. [Gutachter] Pickhard. "Epistaxis - Die Rolle oraler Antikoagulanzien / Nina Peters ; Gutachter: Peter B. Luppa, Anja C. Pickhard ; Betreuer: Anja C. Pickhard". München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1200547624/34.

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Livros sobre o assunto "B.C-449 A.D"

1

Steig, William. C D B. New York: Simon & Schuster Books for Young Readers, 2000.

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2

Seastone, Leonard. A B C D: [...]. [West Sayville, New York: Tideline Press, 2018.

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3

James, Rodgers. A B C D E. Seattle, WA: Caramel Tree Readers, 2014.

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4

Obaydi, Ishak. My A B C D. Calcutta: Educational Pub., 1992.

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5

Jigyōdan, Kitakyūshū-shi Kyōiku Bunka. Babayama iseki: Dai B, C, D chiten. Kitakyūshū: Kitakyūshū-shi Kyōiku Bunka Jigyōdan Maizō Bunkazai Chōsashitsu, 1985.

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6

Sadler, Joyce M. Scioto County, Ohio, obituaries A-B-C-D. Portsmouth, Ohio: Scioto County Chapter of the Ohio Genealogical Society, 2006.

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7

ill, Watson Wendy, ed. A,B,C,D, tummy, toes, hands, knees. New York, N.Y., U.S.A: Viking Kestrel, 1989.

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8

Verlant, Bernard. BTS industriels, groupements B, C, D.: Statistique et probabilités. 2a ed. Paris: Foucher, 2009.

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9

Steig, William. C D B! Prentice Hall, 1988.

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10

Steig, William. C D B! Trumpet Club, 1989.

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Capítulos de livros sobre o assunto "B.C-449 A.D"

1

Daniels, David, Richard J. Hillman, Simon E. Barton e David Goldmeier. "Hepatitis A/B/C/D". In Sexually Transmitted Diseases and AIDS, 52–58. London: Springer London, 1993. http://dx.doi.org/10.1007/978-1-4471-1985-2_6.

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2

Kuchner, Marc. "HR 8799 b, c, and d". In Encyclopedia of Astrobiology, 765–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11274-4_1846.

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3

Cobb, Bryan R., e Alexandra Valsamakis. "Chronic Hepatitis B, C, and D". In Diagnostic Microbiology of the Immunocompromised Host, 69–95. Washington, DC: ASM Press, 2016. http://dx.doi.org/10.1128/9781555819040.ch3.

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4

Emerson, Peter. "The A-B-C-D of Voting". In Democratic Decision-making, 17–32. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-52808-9_3.

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5

Goresky, Mark, e Robert MacPherson. "Proofs of Theorems B, C, and D". In Stratified Morse Theory, 251–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-71714-7_28.

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6

Callier, Frank M., e Charles A. Desoer. "The Discrete-Time System RepresentationR d (·)=[A(·),B(·),C(·),D(·)]". In Springer Texts in Electrical Engineering, 55–67. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-0957-7_3.

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Petkov, Vesselin. "Appendix A, Appendix B, Appendix C, Appendix D". In Relativity and the Nature of Spacetime, 277–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01962-3_11.

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Callier, Frank M., e Charles A. Desoer. "The System Representation R(·) =[A(·), B(·), C(·), D(·)]". In Springer Texts in Electrical Engineering, 5–54. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-0957-7_2.

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9

Callier, Frank M., e Charles A. Desoer. "The Discrete-Time System Representation R d=[A,B,C,D]". In Springer Texts in Electrical Engineering, 95–102. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-0957-7_5.

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Callier, Frank M., e Charles A. Desoer. "The System RepresentationR =[A,B,C,D], Part I". In Springer Texts in Electrical Engineering, 68–94. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-0957-7_4.

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Trabalhos de conferências sobre o assunto "B.C-449 A.D"

1

AUSHEV, T. "CP VIOLATION IN $B \to C\bar{C}D$ DECAYS AT BELLE". In Proceedings of the 32nd International Conference. World Scientific Publishing Company, 2005. http://dx.doi.org/10.1142/9789812702227_0163.

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2

"Oral presentation sessions (A, B, C, D in parallel)". In 2008 International Conference on Electronic Design. IEEE, 2008. http://dx.doi.org/10.1109/iced.2008.4786628.

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3

Lauter, Christoph. "An efficient software implementation of correctly rounded operations extending FMA: A + b + c and a × b + c × d". In 2017 51st Asilomar Conference on Signals, Systems, and Computers. IEEE, 2017. http://dx.doi.org/10.1109/acssc.2017.8335379.

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4

Long, J., e W. Koyama. "F/A-18A/B/C/D 9G flight test program". In 1999 IEEE Aerospace Conference. Proceedings. IEEE, 1999. http://dx.doi.org/10.1109/aero.1999.789771.

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5

Karim, Nor Suriya Abd, e Roslan Hasni. "Chromaticity of 6-bridge graph θ(3,3,3,b,c,d)". In THE 22ND NATIONAL SYMPOSIUM ON MATHEMATICAL SCIENCES (SKSM22): Strengthening Research and Collaboration of Mathematical Sciences in Malaysia. AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4932483.

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6

Rosa, Carla Carmelo, John Rogers, Justin Pedro e Adrian Podoleanu. "Multiscan OCT system for A, T, B, C and 3-D imaging". In Biomedical Optics 2006, editado por Valery V. Tuchin, Joseph A. Izatt e James G. Fujimoto. SPIE, 2006. http://dx.doi.org/10.1117/12.648854.

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7

Witzel, Oliver. "Lattice QCD (focus on Charm and Beauty form factors, R(D*), b- & c-quark masses)". In 18th International Conference on B-Physics at Frontier Machines. Trieste, Italy: Sissa Medialab, 2020. http://dx.doi.org/10.22323/1.377.0037.

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8

Davies, Christine, Rachel Dowdall, Ron Horgan, Peter Lepage, Christopher Monahan e Junko Shigemitsu. "Neutral B-meson mixing with physical u, d, s, and c sea quarks". In The 32nd International Symposium on Lattice Field Theory. Trieste, Italy: Sissa Medialab, 2015. http://dx.doi.org/10.22323/1.214.0373.

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Shen, Guowu, William R. Tyson e James A. Gianetto. "CMOD Compliance of B×B Single Edge Bend Specimens". In ASME 2012 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/pvp2012-78037.

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In ASTM standard E1820, the single edge bend (SE(B)) geometry is one of those recommended for fracture toughness testing. The width to thickness (W/B) ratio recommended in E1820 for this specimen is 2. However, in certain cases, it is desirable to use specimens having alternative W/B ratios; the range of W/B suggested in E1820 is 1 to 4. In E1820, the crack size a may be evaluated during J-integral or CTOD resistance testing using the crack mouth opening displacement (CMOD) elastic unloading compliance C. The equation given to relate a to C using a dimensionless compliance BCE incorporates Young’s modulus E. For the three-dimensional (3-D) SE(B) specimens that are in neither plane stress nor plane strain condition, this parameter E may be considered as a normalizing parameter varying between extremes E (plane stress) and E/(1−ν2) (plane strain) depending on crack depth (a/W) and specimen W/B ratio. In the present study, 3-D finite element analysis (FEA) was used to evaluate the CMOD compliance of B×B SE(B) specimens with shallow and deep cracks and compared with that from Tada’s plane stress equation. Crack sizes evaluated using plane stress and plane strain assumptions with the 3-D CMOD compliance obtained from FEA were compared with the actual crack size of the specimens used in FEA. It was found that the errors in crack size using plane strain or plane stress assumptions can be larger than 5%, especially for shallow-cracked specimens. In the present study, an effective modulus with values between plane stress and plane strain is proposed and evaluated by FEA for the 3-D B×B SE(B) specimens. The values were fitted to a polynomial equation as a function of u = 1/(√(BCE)+1) for use in estimating the dimensionless compliance for crack size evaluation for B×B SE(B) specimens. It is shown that the errors in crack size evaluation can be significantly reduced using this effective modulus.
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10

Liao, Ying-min, e Tai-cheng Lee. "A 6-b 1.3Gs/s A/D Converter with C-2C Switch-Capacitor Technique". In 2006 International Symposium on VLSI Design, Automation and Test (VLSI-DAT). IEEE, 2006. http://dx.doi.org/10.1109/vdat.2006.258136.

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Relatórios de organizações sobre o assunto "B.C-449 A.D"

1

Mugele, R. M., P. T. Dzwilewski e J. T. Cilke. Aircraft Fire Sentry. Volume 2. Appendices A, B, C and D. Fort Belvoir, VA: Defense Technical Information Center, janeiro de 1993. http://dx.doi.org/10.21236/ada270088.

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2

Holubyev, Kostyantyn. Measurement of direct CP violation in b → sc$\bar{c}$ and b → d$\barc{c}$ quark transitions using B+ → J/psiK+ and B+→ J/Ψπ+ decays. Office of Scientific and Technical Information (OSTI), novembro de 2008. http://dx.doi.org/10.2172/968353.

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3

Aubert, B. MEASUREMENT OF THE BRANCHING FRACTIONS FOR INCLUSIVE B{sup -} AND {bar B}{sup 0} DECAYS TO FLAVOR-TAGGED D, D{sub S} AND LAMBDA{sub C}. Office of Scientific and Technical Information (OSTI), agosto de 2004. http://dx.doi.org/10.2172/829763.

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4

Moore, Carole, Paul Hogan, Christian Kirchner, Patrick C. Macklin e Peter M. Greenston. Econometric Estimates of Army Retention: Zones A, B, C, D and Retirement-Eligible, 1990-2004. Fort Belvoir, VA: Defense Technical Information Center, janeiro de 2007. http://dx.doi.org/10.21236/ada464636.

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SGC, Servicio Geológico Colombiano. Estudio Geomorfológico del sector comprendido entre Bocatocino, Atlántico y Ciénaga, Magdalena. Proyecto Andén Caribe - Fase II. Mapas geomorfológicos a escala 1:25.000 de las planchas 17-III-A, 17-III-C, 17-I-B, 17-I-D, 17-III-B, 17-III-D, 17-II-A, 17-II-C, 17-IV-A Y 17-IV-C, 17-II-B, 17-II-D, 18-I-A, 18-I-C, 18-I-D, 18-II-A, 18-II-C, 18-II-B y 18-II-D. Año 2010. Bogotá: Servicio Geológico Colombiano, dezembro de 2010. http://dx.doi.org/10.32685/10.143.2010.139.

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Nelson, O. D. Portable exhausters POR-004 SKID B, POR-005 SKID C, POR-006 SKID D storage plan. Office of Scientific and Technical Information (OSTI), setembro de 1997. http://dx.doi.org/10.2172/341248.

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Bonner, Michael S., e David R. Gingras. Status of a Comprehensive Validation of the Navy's F/A-18A/B/C/D Aerodynamics Model. Fort Belvoir, VA: Defense Technical Information Center, maio de 1996. http://dx.doi.org/10.21236/ada309807.

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Nevalainen, M., e R. H. Jr Dodds. Numerical investigation of 3-D constraint effects on brittle fracture in SE(B) and C(T) specimens. Office of Scientific and Technical Information (OSTI), julho de 1996. http://dx.doi.org/10.2172/367248.

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NOTTINGHAM (H D) AND ASSOCIATES INC MCLEAN VA. Energy Engineering Analysis Program, Fort Drum, New York; Executive Summary, Increments A, B, C, D, G, & F. Fort Belvoir, VA: Defense Technical Information Center, junho de 1986. http://dx.doi.org/10.21236/ada330642.

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De Varela, Ana Lorena, e Silvia Martínez Álvarez. Aprendamos todos a leer: Fascículo 22: Toda la familia lee y escribe conmigo. Inter-American Development Bank, maio de 2022. http://dx.doi.org/10.18235/0004047.

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Aprendamos Todos a Leer es la iniciativa para la enseñanza de lectura y escritura inicial del BID, donde a través de materiales para el alumno, el maestro y el aula de clase, pretende brindar herramientas para apoyar el proceso de alfabetización inicial. El programa se organiza a partir de una cartelera fonológica presentando para cada fonema (sonido de letra) un personaje caracterizado por un animal. En respuesta al COVID-19, se desarrollaron fascículos para apoyar el trabajo en casa. Este fascículo contiene orientaciones para enseñar el sonido y escritura de la letra V-v, su combinación con las vocales y las consonantes M-m, P-p, N-n, L-l, S-s, F-f, T-t, B-b, D-d, C-c, QU-qu.
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