Literatura científica selecionada sobre o tema "Antigen specificity"
Crie uma referência precisa em APA, MLA, Chicago, Harvard, e outros estilos
Índice
Consulte a lista de atuais artigos, livros, teses, anais de congressos e outras fontes científicas relevantes para o tema "Antigen specificity".
Ao lado de cada fonte na lista de referências, há um botão "Adicionar à bibliografia". Clique e geraremos automaticamente a citação bibliográfica do trabalho escolhido no estilo de citação de que você precisa: APA, MLA, Harvard, Chicago, Vancouver, etc.
Você também pode baixar o texto completo da publicação científica em formato .pdf e ler o resumo do trabalho online se estiver presente nos metadados.
Artigos de revistas sobre o assunto "Antigen specificity"
Rhodes, S. G., D. Gavier-Widen, B. M. Buddle, A. O. Whelan, M. Singh, R. G. Hewinson e H. M. Vordermeier. "Antigen Specificity in Experimental Bovine Tuberculosis". Infection and Immunity 68, n.º 5 (1 de maio de 2000): 2573–78. http://dx.doi.org/10.1128/iai.68.5.2573-2578.2000.
Texto completo da fonteJain, Deepti, e Dinakar M. Salunke. "Antibody specificity and promiscuity". Biochemical Journal 476, n.º 3 (5 de fevereiro de 2019): 433–47. http://dx.doi.org/10.1042/bcj20180670.
Texto completo da fonteKendall-Taylor, P., D. Jones e S. Atkinson. "The specificity of autoantibodies in Graves' ophthalmopathy". Acta Endocrinologica 116, n.º 1_Suppl (agosto de 1987): S330—S333. http://dx.doi.org/10.1530/acta.0.114s330.
Texto completo da fonteJiang, Ning, Ke-yue Ma, Alexandra A. Schonnesen, Chenfeng He, Amanda Xia, Eric Sun, Eunise Chen, Katherine Sebastian, Robert Balderas e Mrinalini Kulkarni-Date. "High-Throughput and High-Dimensional Single Cell Analysis of Antigen-Specific CD8+ T cells". Journal of Immunology 206, n.º 1_Supplement (1 de maio de 2021): 27.22. http://dx.doi.org/10.4049/jimmunol.206.supp.27.22.
Texto completo da fonteLesavre, Philippe. "Antineutrophil Cytoplasmic Autoantibodies Antigen Specificity". American Journal of Kidney Diseases 18, n.º 2 (agosto de 1991): 159–63. http://dx.doi.org/10.1016/s0272-6386(12)80873-0.
Texto completo da fonteBolhuis, Reinder L. H., Els Sturm, Jan Willem Gratama e Eric Braakman. "Engineering T lymphocyte antigen specificity". Journal of Cellular Biochemistry 47, n.º 4 (dezembro de 1991): 306–10. http://dx.doi.org/10.1002/jcb.240470404.
Texto completo da fonteKlinger, Mark, Ruth Taniguchi, Joyce Hu, Tim Hayes, Tobias Wittkop, Thomas Asbury, Martin Moorhead et al. "A scalable multiplex assay enabling assessment of T cell receptor specificity to hundreds of self- and pathogen-derived antigens". Journal of Immunology 196, n.º 1_Supplement (1 de maio de 2016): 209.4. http://dx.doi.org/10.4049/jimmunol.196.supp.209.4.
Texto completo da fonteShahi, Payam, Bruce Adams, Daniel Reyes, Shamoni Maheshwari, Nima Mousavi, Sreenath Krishnan, Nandhini Ramen et al. "High-Throughput Antibody Discovery Using Barcode Enabled Antigen Mapping (BEAM". Journal of Immunology 210, n.º 1_Supplement (1 de maio de 2023): 249.28. http://dx.doi.org/10.4049/jimmunol.210.supp.249.28.
Texto completo da fonteTseng, Diane, Shin-Heng Chiou, Xinbo Yang, Alexandre Reuben, Julie Wilhelmy, Alana McSween, Stephanie Conley et al. "Discovery of a novel shared tumor antigen in human lung cancer." Journal of Clinical Oncology 38, n.º 15_suppl (20 de maio de 2020): 3087. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.3087.
Texto completo da fonteZollinger, Wendell D., Elizabeth E. Moran e Deborah H. Schmiel. "Characterization of an Antibody Depletion Assay for Analysis of Bactericidal Antibody Specificity". Clinical and Vaccine Immunology 16, n.º 12 (14 de outubro de 2009): 1789–95. http://dx.doi.org/10.1128/cvi.00255-09.
Texto completo da fonteTeses / dissertações sobre o assunto "Antigen specificity"
Košmrlj, Andrej 1981. "Statistical physics of T cell receptor development and antigen specificity". Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68875.
Texto completo da fonteCataloged from PDF version of thesis.
Includes bibliographical references (p. 147-158).
Higher organisms, such as humans, have an adaptive immune system that usually enables them to successfully combat diverse (and evolving) microbial pathogens. The adaptive immune system is not preprogrammed to respond to prescribed pathogens, yet it mounts pathogen-specific responses against diverse microbes, and establishes memory of past infections (the basis of vaccination). Although major advances have been made in understanding pertinent molecular and cellular phenomena, the mechanistic principles that govern many aspects of an immune response are not known. In this thesis, I illustrate how complementary approaches from the physical and life sciences can help confront this challenge. Specifically, I describe work that brings together statistical mechanics and cell biology to shed light on how key regulators of the adaptive immune system, T cells, are selected to enable pathogen-specific responses. A model of T cell development is introduced and analyzed (computationally and analytically) by employing methods from statistical physics, such as extreme value distributions and Hamiltonian minimization. Results show that selected T cell receptors are enriched in weakly interacting amino acids. Such T cell receptors recognize (i.e. bind sufficiently strongly to) pathogens through several contacts of moderate strength, each of which makes a significant contribution to overall binding. Disrupting any contact by mutating the pathogen is statistically likely to abrogate T cell recognition of the mutated pathogen. We propose that this is the mechanism for the specificity of T cells for unknown pathogens. The T cell development model is also used to discuss one way in which host genetics can influence the selection of T cells and concomitantly the control of HIV infection. A model of the T cell selection process as diffusion in a random field of immobile traps that intermittently turn "on" and "off" is developed to estimate the escape probability of dangerous T cells that could cause autoimmune disease. Finally, and importantly, throughout this thesis, I describe, how the theoretical studies are closely synergistic/complementary with biological experiments and human clinical data.
by Andrej Košmrlj.
Ph.D.
Sandberg, Johan. "CD8⁺ T cell specificity in thymic selection and in the recognitionof antigen /". Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3686-2/.
Texto completo da fonteForsström, Björn. "Characterization of antibody specificity using peptide array technologies". Doctoral thesis, KTH, Proteomik och nanobioteknologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-155723.
Texto completo da fonteQC 20141111
Moots, Robert J. "The fine specificity of HLA class I-restricted antigen recognition by cytotoxic T lymphocytes". Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315327.
Texto completo da fontePeche, Leticia Yamila. "Evidence of functional specificity within the MAGE-I family of tumor expressed proteins". Doctoral thesis, SISSA, 2008. http://hdl.handle.net/20.500.11767/4674.
Texto completo da fonteRIGAMONTI, VALERIA. "Development of a quantitative chemiluminescent immunoassay for the hepatitis B. antigen detection". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/19390.
Texto completo da fonteRoter, Evan. "Beta2-glycoprotein I-specific T cells: antigen specificity and role in the induction of anti-phospholipid syndrome". Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86847.
Texto completo da fonteLe syndrome antiphospholipide (SAPL) est une maladie autoimmune caractérisée par la présence d'auto-anticorps antiphospholipides (aPL) dirigés contre des protéines liant les phospholipides anioniques dont la β2-glycoproteine I (β2GPI), ainsi que par des manifestations cliniques incluant la thrombose et la perte foetale récurrente. Les patients souffrant du SAPL possèdent des lymphocytes T sensibles au β2GPI mais leurs origines restent inconnues. Nous posons donc l'hypothèse que des souris immunisées avec β2GPI humain produiraient des lymphocytes T sensibles au β2GPI endogène. De surcroit, nous proposons que l'oxydation, la réduction, ou la liaison du β2GPI aux phospholipides affecterait l'identification du β2GPI par les lymphocytes T. Après de nombreuses immunisations avec du β2GPI humain, des lymphocytes T de rate provenant de souris C57BL/6 produisent de l'interferon-γ (IFN-γ) en présence soit de β2GPI humain - isolé ou lié à un phospholipide anionique; de β2GPI humain réduit; ainsi, mais à un degré moindre, de β2GPI humain oxydé. Toutefois, les lymphocytes T n'ont produit pas de réponses à aucune forme de β2GPI murin qui soient. Des résultats similaires avec hybridomes de lymphocytes T sensibles au β2GPI furent aussi obtenus. D'autre part des anticorps contre le β2GPI murin furent obtenus à la suite d'immunisations, utilisant du β2GPI humain ou murin conjointement avec de l'adjuvant de Freund, mais aucune réponse de lymphocytes T sensibles au β2GPI furent observée. Nos résultats indiquent que la tolérance des lymphocytes B au β2GPI autologue peut être brisée en absence d'une réponse détectable in vitro de lymphocytes T au β2GPI.
Johansson, Daniel X. "Expression and interaction studies of recombinant human monoclonal antibodies /". Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-137-1/.
Texto completo da fonteBabakhani, Farah Kondori 1960. "IN VITRO PRODUCTION AND SPECIFICITY OF ANTI-DNA AUTO ANTIBODIES BY NEW ZEALAND BLACK/NEW ZEALAND WHITE F1 MICE". Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276471.
Texto completo da fonteLagardien, Zaida. "The characterisation of the peanut agglutinin an evolved plant lectin, with improved specificity to the Thompson Freidenriech antigen". Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3136.
Texto completo da fonteIncludes bibliographical references.
Peanut agglutinin (PNA), a carbohydrate binding protein, is able to recognise and bind a number of distinct carbohydrate structures that have been implicated in a number of disease pathologies in humans. In vitro studies of PNA have previously been shown to have some specificity for the Thomson Freidenriech antigen (T-antigen), found on malignant human cells, and this specificity has made PNA an important target for protein engineering experiments aimed at improving its specificity and affinity. A number of tumour cells are characterised by altered states and patterns of glycosylation on cell surfaces and suitably engineered lectins may be able to recognise tumour specific carbohydrate structures. This study was aimed at carrying out the biophysical characterisation of a set of PNA mutants which showed apparent improvement in specificity for the T-Antigen. Previous studies have aimed to engineer this lectin in order to direct its recognition properties towards the T-antigen and away from lactose, the preliminary binding affinities of these mutants being determined using Surface Plasmon Resonance (SPR). Here a set of PNA mutants were characterised, proteins expressed and purified to determine binding activities to the T-antigen, N-Acetyl-Dlactosamine (LacNAc) and lactose through the use of Protein Micro Array technology as well as Enzyme linked immunosorbant assays (ELISA).
Livros sobre o assunto "Antigen specificity"
Schenkel-Brunner, Helmut. Human blood groups: Chemical and biochemical basis of antigen specificity. Wien: Springer-Verlag, 1995.
Encontre o texto completo da fonteSchenkel-Brunner, Helmut. Human blood groups: Chemical and biochemical basis of antigen specificity. 2a ed. Wien: Springer, 2000.
Encontre o texto completo da fonteHuman blood groups: Chemical and biochemical basis of antigen specificity. 2a ed. Wien: Springer, 2000.
Encontre o texto completo da fonteHuman blood groups: Chemical and biochemical basis of antigen specificity. Wien: Springer-Verlag, 1995.
Encontre o texto completo da fonteK, Pfeffer, ed. Function and specificity of [alpha/delta] T cells: International Workshop, Schloss Elmau, Bavaria, FRG, October 14-16, 1990. Berlin: Springer, 1991.
Encontre o texto completo da fonteWorkshop on Mechanisms and Specificity of HIV Entry into Host Cells (1989 San Francisco, Calif.). Mechanisms and specificity of HIV entry into host cells. New York: Plenum Press, 1991.
Encontre o texto completo da fonteSpecial Programme for Research and Training in Tropical Diseases, Foundation for Innovative New Diagnostics e Centers for Disease Control and Prevention (U.S.), eds. Malaria rapid diagnostic test performance: Results of WHO product testing of malaria RDTs : round 2 (2009). Geneva: World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases, 2010.
Encontre o texto completo da fonteservice), ScienceDirect (Online, ed. Tissue-specific vascular endothelial signals and vector targeting. Amsterdam: Elsevier, 2009.
Encontre o texto completo da fonteLandsteiner, Karl. The Specificity of Serological Reactions. Dover Publications, 1990.
Encontre o texto completo da fonteIvanyi, Juraj, e Tom H. M. Ottenhoff, eds. Significance of antigen and epitope specificity in tuberculosis. Frontiers SA Media, 2015. http://dx.doi.org/10.3389/978-2-88919-451-3.
Texto completo da fonteCapítulos de livros sobre o assunto "Antigen specificity"
Band, H., St A. Porcelli, G. Panchamoorthy, J. Mclean, C. T. Morita, S. Ishikawa, R. L. Modlin e M. B. Brenner. "Antigens and Antigen-Presenting Molecules for γδ T Cells". In Function and Specificity of γ/δ T Cells, 229–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_32.
Texto completo da fonteMorris, Emma C., e J. H. F. Falkenburg. "What Defines a Good Tumour Antigen?" In The EBMT/EHA CAR-T Cell Handbook, 11–14. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_3.
Texto completo da fonteLund, Ole, Edita Karosiene, Claus Lundegaard, Mette Voldby Larsen e Morten Nielsen. "Bioinformatics Identification of Antigenic Peptide: Predicting the Specificity of Major MHC Class I and II Pathway Players". In Antigen Processing, 247–60. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-218-6_19.
Texto completo da fonteWang, Chunlin, Huang Huang e Mark M. Davis. "Grouping T-Cell Antigen Receptors by Specificity". In Methods in Molecular Biology, 291–307. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2712-9_15.
Texto completo da fonteVan Regenmortel, Marc H. V. "Specificity, Polyspecificity and Heterospecificity of Antibody-Antigen Recognition". In HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design, 39–56. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-32459-9_4.
Texto completo da fonteDent, A. L., e S. M. Hedrick. "Mechanisms of Development of αβ T Cell Antigen Receptor-Bearing Cells in γδ T Cell Antigen Receptor Transgenic Mice". In Function and Specificity of γ/δ T Cells, 121–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_17.
Texto completo da fonteDe Libero, G., G. Casorati, N. Migone e A. Lanzavecchia. "Correlation Between TCRV Gene Usage and Antigen Specificities in Human γδ T Cells". In Function and Specificity of γ/δ T Cells, 235–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_33.
Texto completo da fontePowell, Daniel J., e Bruce L. Levine. "Genetically Engineered Antigen Specificity in T Cells for Adoptive Immunotherapy". In Experimental and Applied Immunotherapy, 251–78. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-980-2_12.
Texto completo da fonteHoloshitz, J., N. K. Bayne, D. R. McKinley e Y. Jia. "A Dichotomy Between the Cytolytic Activity and Antigen-Induced Proliferative Response of Human γδ T Cells". In Function and Specificity of γ/δ T Cells, 167–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_22.
Texto completo da fonteLefrancois, L., R. LeCorre, Judy Mayo, J. A. Bluestone e T. Goodman. "Selection of Vδ+ T Cell Receptors of Intestinal Intraepithelial Lymphocytes is Dependent on Class II Histocompatibility Antigen Expression". In Function and Specificity of γ/δ T Cells, 255–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_36.
Texto completo da fonteTrabalhos de conferências sobre o assunto "Antigen specificity"
Kleist, Sierra, Shawn Musial, Hanna Degefu, Pamela Rosato e Jordan Isaacs. "1032 Uncoupling CD39 and T cell antigen specificity in brain tumors". In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.1032.
Texto completo da fontePark, Seungtae, Sungsik Kim, Hee Joon Jeon, Na Ri Yoon, Bo Ryeong Lee, Sung-min Kim, Woong-Yang Park e Hyung Ju Hwang. "74 DeepTCRMatch: An effective way of computing T cells antigen specificity". In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.0074.
Texto completo da fonteChen, Liang, Chunlin Wang e Mark Davis. "Abstract PR14: Identification of specificity TCR groups of tumor antigen specific T-cells". In Abstracts: Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 30 - October 3, 2018; New York, NY. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr18-pr14.
Texto completo da fonteSantoso, S., Y. Shibata, V. Kiefel e C. Mueller-Eckhardt. "IDENTIFICATION OF YUK(b) ALLOANTIGEN ON PLATELET GLYCOPROTEIN IIIa*". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643528.
Texto completo da fonteSilveira, A. M. V., B. Hessel e B. Blombäck. "VON WILLEBRAND FACTOR (VWF) ANTIGENS IN URINE". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644083.
Texto completo da fonteFisher, Jonathan, anna capsomidis, Barry Flutter, Gabriel Benthal, Rebcca Wallace, Kenth Gustafsson, Karin Straathof, Martin Pule e John Anderson. "Abstract B128: Chimeric antigen receptor transduced gamma delta T lymphocytes provide enhanced tumor specificity". In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-b128.
Texto completo da fonteAdams, Gregor B., Jun Feng, Atefeh Ghogha, Armen Mardiros, Ruben Rodriguez, Tassja J. Spindler, Jed Wiltzius e Tony Polverino. "Abstract 2135: Selectivity and specificity of engineered T cells expressing KITE-585, a chimeric antigen receptor targeting B-cell maturation antigen (BCMA)". In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2135.
Texto completo da fonteSchirmer, David, Richard Klar, Oxana Schmidt, Dirk Wohlleber, Wolfgang Uckert, Uwe Thiel, Felix Bohne et al. "Abstract 3202: Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity". In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3202.
Texto completo da fonteBanerjee, Rupak K., Meinrad Praxmaraer, Ilhan Dilber, Peter Bungay, William van Osdol e Cynthia Sung. "Numerical Simulation of Antibody Penetration in a Solid Tumor Nodule Using Finite Element Method". In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0058.
Texto completo da fonteXiao, Yang, Yueshan Huang, Yu Zhao, Fan Xu, Qin Ren, Bing He, Jianhua Yao e Xiao Liu. "Multimodal-AIR-BERT: A Multimodal Pre-trained Model for Antigen Specificity Prediction in Adaptive Immune Receptors". In 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2023. http://dx.doi.org/10.1109/bibm58861.2023.10385479.
Texto completo da fonteRelatórios de organizações sobre o assunto "Antigen specificity"
Friedmann, Michael, Charles J. Arntzen e Hugh S. Mason. Expression of ETEC Enterotoxin in Tomato Fruit and Development of a Prototype Transgenic Tomato for Dissemination as an Oral Vaccine in Developing Countries. United States Department of Agriculture, março de 2003. http://dx.doi.org/10.32747/2003.7585203.bard.
Texto completo da fonte