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Artigos de revistas sobre o assunto "Anatomy and physiology Swine"

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Hughes, G. Chad, Mark J. Post, Michael Simons e Brian H. Annex. "Translational Physiology: Porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis". Journal of Applied Physiology 94, n.º 5 (1 de maio de 2003): 1689–701. http://dx.doi.org/10.1152/japplphysiol.00465.2002.

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“Therapeutic angiogenesis” describes an emerging field of cardiovascular medicine whereby new blood vessels are induced to grow to supply oxygen and nutrients to ischemic cardiac or skeletal muscle. Various methods of producing therapeutic angiogenesis have been employed, including mechanical means, gene therapy, and the use of growth factors, among others. The use of appropriate large-animal models is essential if these therapies are to be critically evaluated in a preclinical setting before their use in humans, yet little has been written comparing the various available models. Over the past decade, swine have been increasingly used in studies of chronic ischemia because of their numerous similarities to humans, including minimal preexisting coronary collaterals as well as similar coronary anatomy and physiology. Consequently, this review describes the most commonly used swine models of chronic myocardial ischemia with special attention to regional myocardial blood flow and function and critically evaluates the strengths and weaknesses of each model in terms of utility for preclinical trials of angiogenic therapies.
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XANTHOS (Θ. ΞΑΝΘΟΣ), Th. "Swine model in cardiopulmonary resuscitation research". Journal of the Hellenic Veterinary Medical Society 60, n.º 3 (20 de novembro de 2017): 254. http://dx.doi.org/10.12681/jhvms.14935.

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Cardiac Arrest (CA) constitutes a real medical emergency. Various experimental models have been developed in order to test experimental treatments. Animal models that have been used in CA research are rodents, rabbits, cats and dogs, primates and swine. Among these, swine are used more often. The reason behind this choice is mostly its close resemblance to the human cardiac anatomy and physiology. Various haemodynamic variables have been investigated as predictors of the return of spontaneous circulation (ROSC). Coronary Perfusion Pressure (CPP) is the only proven predictor for ROSC. CPP, which is responsible for myocardial perfusion, greatly augments during chest compressions. ROSC and therefore survival after CA has been associated with CCP values greater than 15 mmHg for humans and 25 mmHg for animals. For the experimental induction of CA various electric sources have been used. All these experimental devices could be potentially dangerous for researchers, even though, no incidence of electrocution has been reported in the international literature. The ordinary cadmium battery appears to be safer and is an extremely effective way of inducing cardiac arrest.
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Poonsuk, Korakrit, e Jeff Zimmerman. "Historical and contemporary aspects of maternal immunity in swine". Animal Health Research Reviews 19, n.º 1 (10 de novembro de 2017): 31–45. http://dx.doi.org/10.1017/s1466252317000123.

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AbstractMaternal immunity plays a pivotal role in swine health and production because piglets are born agammaglobulinemic and with limited cell-mediated immunity, i.e. few peripheral lymphoid cells, immature lymphoid tissues, and no effector and memory T-lymphocytes. Swine do not become fully immunologically competent until about 4 weeks of age, which means that their compromised ability to respond to infectious agents during the first month of life must be supplemented by maternal immune components: (1) circulating antibodies derived from colostrum; (2) mucosal antibodies from colostrum and milk; and (3) immune cells provided in mammary secretions. Because maternal immunity is highly effective at protecting piglets against specific pathogens, strengthening sow herd immunity against certain diseases through exposure or vaccination is a useful management tool for ameliorating clinical effects in piglets and delaying infection until the piglets’ immune system is better prepared to respond. In this review, we discuss the anatomy and physiology of lactation, the immune functions of components provided to neonatal swine in mammary secretion, the importance of maternal immunity in the prevention and control of significant pathogens.
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Chade, Alejandro R., Maxx L. Williams, Jason Engel, Erika Guise e Taylor W. Harvey. "A translational model of chronic kidney disease in swine". American Journal of Physiology-Renal Physiology 315, n.º 2 (1 de agosto de 2018): F364—F373. http://dx.doi.org/10.1152/ajprenal.00063.2018.

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Animal models of chronic kidney disease (CKD) are critical for understanding its pathophysiology and for therapeutic development. The cardiovascular and renal anatomy and physiology of the pig are virtually identical to humans. This study aimed to develop a novel translational model of CKD that mimics the pathological features of CKD in humans. CKD was induced in seven domestic pigs by bilateral renal artery stenosis and diet-induced dyslipidemia. Animals were observed for a total of 14 wk. Renal hemodynamics and function were quantified in vivo using multi-detector CT after 6, 10, and 14 wk of CKD. Urine and blood were collected at each time-point, and blood pressure was continuously measured (telemetry). After completion of in vivo studies, pigs were euthanized, kidneys were removed, and microvascular (MV) architecture (μCT), markers of renal injury, inflammation, and fibrosis were evaluated ex vivo. Additional pigs were used as controls ( n = 7). Renal blood flow and glomerular filtration were reduced by 50% in CKD, accompanied by hypertension and elevated plasma creatinine, albumin-to-creatinine ratio and increased urinary KIM-1 and NGAL, suggesting renal injury. Furthermore, 14 wk of CKD resulted in cortical and medullary MV remodeling and loss, inflammation, glomerulosclerosis, tubular atrophy, and tubule-interstitial fibrosis compared with controls. The current study characterizes a novel model of CKD that mimics several of the pathological features observed in human CKD, irrespective of the etiology. Current approaches only slow rather than halt CKD progression, and this novel model may offer a suitable platform for the development of new treatments in a translational fashion.
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Safranski, Timothy J. "34 Swine Breeding Herd Practicum Winternship". Journal of Animal Science 100, Supplement_2 (12 de abril de 2022): 120. http://dx.doi.org/10.1093/jas/skac064.203.

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Abstract Approximately 70% of Animal Science students at Mizzou enroll without large animal experience, and commercial swine production exposure is very low (1-3%). As such, few consider careers in the swine industry. Winter break is 4 or 5 weeks long, allowing more than enough family time. An opportunity for full-time employment for students for 1-2 weeks over winter break on commercial sow units was arranged for 1 or 2 students each of 2 years. Host farms reported students were ‘shell shocked’ for the first 3 or 4 d, finding the scope of production overwhelming. A more formal program was designed to introduce students to modern swine breeding herd management, combining academic and field training over a period of several months. Eligible students have at least sophomore standing, can demonstrate a sincere interest in learning about careers in commercial pork production, and are able to commute to farms within 2 hr of campus. Cooperating farms provide hands-on experience on a modern commercial sow farm, help arrange housing, and pay students nominally during the winter break portion. Students are interviewed, and those selected to participate (n = up to 6) sign a code of conduct and participation agreement. In the fall semester they attend 8 hours of classroom instruction covering: gilt development; isolation/acclimation and biosecurity; reproductive anatomy/physiology; detection and synchronization of estrus; artificial insemination; pregnancy diagnosis; farrowing room preparation; induction of farrowing; obstetrical intervention; colostrum management; d 1 pig care; feeding and handling sows and piglets; careers. Interspersed on weekends during fall semester are 3 weekend days shadowing/working in pairs on commercial farms within 1.5 hours of campus. This training prepares them for ‘full time employment’ on a breeding farm, and students work for 1 or 2 weeks over the winter break on commercial sow units. Upon completion of the full-time employment phase, students prepare a written summary of their experience, upon which the majority of their grade rests.
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Doulamis, Ilias P., Alvise Guariento, Thomas Duignan, Takashi Kido, Arzoo Orfany, Mossab Y. Saeed, Viktoria H. Weixler et al. "Mitochondrial transplantation by intra-arterial injection for acute kidney injury". American Journal of Physiology-Renal Physiology 319, n.º 3 (1 de setembro de 2020): F403—F413. http://dx.doi.org/10.1152/ajprenal.00255.2020.

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Acute kidney injury is a common clinical disorder and one of the major causes of morbidity and mortality in the postoperative period. In this study, the safety and efficacy of autologous mitochondrial transplantation by intra-arterial injection for renal protection in a swine model of bilateral renal ischemia-reperfusion injury were investigated. Female Yorkshire pigs underwent percutaneous bilateral temporary occlusion of the renal arteries with balloon catheters. Following 60 min of ischemia, the balloon catheters were deflated and animals received either autologous mitochondria suspended in vehicle or vehicle alone, delivered as a single bolus to the renal arteries. The injected mitochondria were rapidly taken up by the kidney and were distributed throughout the tubular epithelium of the cortex and medulla. There were no safety-related issues detected with mitochondrial transplantation. Following 24 h of reperfusion, estimated glomerular filtration rate and urine output were significantly increased while serum creatinine and blood urea nitrogen were significantly decreased in swine that received mitochondria compared with those that received vehicle. Gross anatomy, histopathological analysis, acute tubular necrosis scoring, and transmission electron microscopy showed that the renal cortex of the vehicle-treated group had extensive coagulative necrosis of primarily proximal tubules, while the mitochondrial transplanted kidney showed only patchy mild acute tubular injury. Renal cortex IL-6 expression was significantly increased in vehicle-treated kidneys compared with the kidneys that received mitochondrial transplantation. These results demonstrate that mitochondrial transplantation by intra-arterial injection provides renal protection from ischemia-reperfusion injury, significantly enhancing renal function and reducing renal damage.
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Liu, Yang, Mehdi Abbasi, Jorge L. Arturo Larco, Ramanathan Kadirvel, David F. Kallmes, Waleed Brinjikji e Luis Savastano. "Preclinical testing platforms for mechanical thrombectomy in stroke: a review on phantoms, in-vivo animal, and cadaveric models". Journal of NeuroInterventional Surgery 13, n.º 9 (15 de março de 2021): 816–22. http://dx.doi.org/10.1136/neurintsurg-2020-017133.

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Preclinical testing platforms have been instrumental in the research and development of thrombectomy devices. However, there is no single model which fully captures the complexity of cerebrovascular anatomy, physiology, and the dynamic artery-clot-device interaction. This article provides a critical review of phantoms, in-vivo animal, and human cadaveric models used for thrombectomy testing and provides insights into the strengths and limitations of each platform. Articles published in the past 10 years that reported thrombectomy testing platforms were identified. Characteristics of each test platform, such as intracranial anatomy, artery tortuosity, vessel friction, flow conditions, device-vessel interaction, and visualization, were captured and benchmarked against human cerebral vessels involved in large-vessel occlusion stroke. Thrombectomy phantoms have been constructed from silicone, direct 3D-printed polymers, and glass. These phantoms represent oversimplified patient-specific cerebrovascular geometry but enable adequate visualization of devices and clots under appropriate flow conditions. They do not realistically mimic the artery-clot interaction. For the animal models, arteries from swine, canines, and rabbits have been reported. These models can reasonably replicate the artery-clot-device interaction and have the unique value of evaluating the safety of thrombectomy devices. However, the vasculature geometries are substantially less complex and flow conditions are different from human cerebral arteries. Cadaveric models are the most accurate vascular representations but with limited access and challenges in reproducibility of testing conditions. Multiple test platforms should be likely used for comprehensive evaluation of thrombectomy devices. Interpretation of the testing results should take into consideration platform-specific limitations.
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Taha, Aladdin, Joaquim Bobi, Ruben Dammers, Rick M. Dijkhuizen, Antje Y. Dreyer, Adriaan C. G. M. van Es, Fabienne Ferrara et al. "Comparison of Large Animal Models for Acute Ischemic Stroke: Which Model to Use?" Stroke 53, n.º 4 (abril de 2022): 1411–22. http://dx.doi.org/10.1161/strokeaha.121.036050.

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Translation of acute ischemic stroke research to the clinical setting remains limited over the last few decades with only one drug, recombinant tissue-type plasminogen activator, successfully completing the path from experimental study to clinical practice. To improve the selection of experimental treatments before testing in clinical studies, the use of large gyrencephalic animal models of acute ischemic stroke has been recommended. Currently, these models include, among others, dogs, swine, sheep, and nonhuman primates that closely emulate aspects of the human setting of brain ischemia and reperfusion. Species-specific characteristics, such as the cerebrovascular architecture or pathophysiology of thrombotic/ischemic processes, significantly influence the suitability of a model to address specific research questions. In this article, we review key characteristics of the main large animal models used in translational studies of acute ischemic stroke, regarding (1) anatomy and physiology of the cerebral vasculature, including brain morphology, coagulation characteristics, and immune function; (2) ischemic stroke modeling, including vessel occlusion approaches, reproducibility of infarct size, procedural complications, and functional outcome assessment; and (3) implementation aspects, including ethics, logistics, and costs. This review specifically aims to facilitate the selection of the appropriate large animal model for studies on acute ischemic stroke, based on specific research questions and large animal model characteristics.
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Vollmar, B., W. Bay, C. Özbek, K. D, Heib, M. D. Menger e H. J. Schieffer. "Experimental intracoronary stenting: comprehensive experience in a porcine model". Laboratory Animals 32, n.º 2 (1 de abril de 1998): 191–99. http://dx.doi.org/10.1258/002367798780599965.

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Appropriate animal models for intracoronary stenting are most important for improving understanding of the pathophysiology of acute occlusion and long-term re-stenosis, which currently limits the safety and efficacy of percutaneous transluminal coronary angioplasty in humans. Since the anatomy and physiology of swine coronary arteries closely resemble those of humans, the procine model should be ideal for testing of stents. This is a comprehensive report on an experimental set-up in pigs, communicating in detail the necessary techniques as well as some modifications facilitating safe intra coronary stent placement and successful follow-up studies for weeks or months. Stent procedure is performed in mechanically ventilated and haemodynamically monitored animals under balanced anaesthesia. Intracoronary application of flow wires allows the assessment of local flow conditions, flow properties and coronary flow reserve. Real-time intravascular ultrasonography (IVUS) provides detailed information on coronary morphology and enables the appropriate sizing of the coronary lumen. From our own experience, we like to propose that the use of the porcine model has the potential to gain new insights into the pathophysiology of intracoronary stent placement-associated complications and allows for the study of modifications in techniques and materials, and the development of novel pharmacological therapeutic strategies.
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Fabino Neto, Ronaildo, João Paulo Belém de Sousa, Letícia Fernandes Xavier Costa, Danyane Pereira Marques, Ingrid Lorrainy da Silva Oliveira, Isadora Cristina Alves Silva, Marcelo Marcondes de Godoy e Flávia Oliveira Abrão Pessoa. "ASPECTOS DO MANEJO REPRODUTIVO DE SUÍNOS". COLLOQUIUM AGRARIAE 13, Especial 2 (1 de junho de 2017): 41–50. http://dx.doi.org/10.5747/ca.2017.v13.nesp2.000207.

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This review was carried out with the purpose of describing the main reproductive management used in the rearing of pigs. Currently, swine breeding in Brazil has average production parameters of 9.5 piglets / calving with 1.9 calving / year, with a genetic potential to reach 13 piglets / calving with 2.6 calving / year. To obtain these zootechnical indexes in pig production, it is necessary to invest in reproductive technologies such as artificial insemination, adequate facilities and frequent training of the workforce. In this sense, to be successful in reproduction, it becomes necessary to know the anatomy and physiology of the male and female reproductive system. The good reproductive performance of the animals also depends on the criterion of selection of the boar and the matrices applied in the breeding. It is fundamental to know the estrous cycle, as well as, the behavior of the nut in estrus to obtain success in artificial insemination or natural mating. The gestation period, as well as childbirth, are critical breeding phases and should be well conducted with the aim of avoiding or reducing piglet mortality. Therefore, the reproductive stages of pigs should be well conducted with special attention to food and sanitary management. The knowledge of the reproductive management by the producer and / or technician responsible for the farm is of fundamental importance to achieve good productive indexes
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Teses / dissertações sobre o assunto "Anatomy and physiology Swine"

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RODRIGUES, PRISCILA ANDRADE MAGALHAES. "ANATOMY E PHYSIOLOGY OF AN APPRENTICESHIP". PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2009. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=14119@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
A pesquisa procura investigar como um estágio supervisionado na formação de professores acontece em uma escola de educação básica. Este estudo tem como base o projeto O estágio nos cursos de formação de professores como uma via de mão dupla entre universidade e escola, que buscou juntar todos os envolvidos no estágio - estagiários, professores supervisores de estágio e professores regentes - para a discussão conjunta sobre o papel do estágio na formação de futuros docentes. Os sujeitos centrais desta pesquisa são aqueles envolvidos nesse projeto, em seu primeiro semestre de desenvolvimento, ao redor de dois cursos de formação de professores da PUC-Rio, Geografia e Letras (Português-Inglês), e de uma escola municipal do Rio de Janeiro. Foram entrevistados oito estagiários, quatro professores supervisores de estágio, dois professores regentes e a diretora da escola. Durante dois meses, as aulas dos dois professores regentes, das respectivas licenciaturas, foram observadas com e sem a presença de seus estagiários. Além disso, as reuniões e encontros com todos os envolvidos foram acompanhados, na tentativa de entender como o estágio se desenvolvia em todas as suas dimensões. A literatura que entende a escola como espaço real da formação inicial e continuada e do desenvolvimento profissional de professores, como se observa em Nóvoa, Perrenoud, Canário, Roldão, Tardif, Lüdke, entre outros, dá sustentação à pesquisa, juntamente com a literatura sobre estágio de Ghedin, Pimenta e Lima. A análise do estágio já foi feita pelos trabalhos de Cardozo (2003) e Albuquerque (2007), um pela ótica dos alunos estagiários, outro pela ótica dos professores regentes. A presente dissertação analisa o estágio supervisionado pela ótica da escola, contribuindo, assim, para sua análise do estágio em três diferentes perspectivas. As constatações indicam que o estágio, no contexto aqui estudado, constitui rica possibilidade de troca entre os envolvidos, mobilizando todos, inclusive os alunos da escola, ou seja, provocando algum tipo de movimento interno de cada sujeito. O estágio observado revelou-se também como mais significativo e menos burocrático para os estudantes, favorecendo a imersão desses futuros professores em seu contexto de trabalho. Constata-se ainda que a aproximação entre todos os sujeitos, estagiários, supervisores de estágio e professores da escola, em uma proposta conjunta de estágio, permite entender o cruzamento de saberes entre universidade e escola. A adesão de todos os envolvidos no estágio a um projeto comum abre possibilidades para se pensar em futuras propostas de formação docente em real colaboração entre estas duas instituições formadoras de professores.
This research seeks to investigate how a supervised teaching practice occurs at a secondary school during teacher education. The study is based on the project Teaching practice in courses for teacher education as a two-way road between university and school, which has sought to bring together those who are involved in teaching practice, such as future teachers, teacher trainers and school teachers, in order to discuss with the group the role of teaching practice in the training of future teachers. The central subjects of this research are those who are involved in the above mentioned project, mainly in its first six months. They come from two teacher education degree courses for teachers in PUC-Rio - Geography and Languages (Portuguese-English) - and from a public sector secondary school in Rio de Janeiro. We interviewed eight future teachers, four teacher trainers, two school teachers and the principal of the school involved. During two months, we observed the classes with or without the presence of future teachers. Besides, we have participated in every meeting with the people involved in the project, in the attempt to understand how the teaching practice would develop as a whole. Our bibliographical support is the literature on school as a real space of initial and continual training and of teacher professional development, as it is possible to learn from Nóvoa, Perrenoud, Canário, Roldão, Tardif and Lüdke among others. We also based our study on the literature on teaching practice taken from Ghedin, Pimenta and Lima as well as on the analysis of teaching practice that has already been carried out by Cardozo (2003) and Albuquerque (2007), the former from the perspective of future teachers, and the latter from that of the school teachers. This dissertation analyzes teaching practice departing from the school, contributing to the analysis of supervised teaching practice from three different perspectives. The analyses indicates that teaching practice, in the context in which we have studied, constitutes a rich opportunity for interchange between those who are involved in it, mobilizing everyone, including the students attending the school; that is, leading to some kind of internal movement of every subject. The observed teaching practice also reveals itself as more significant and less bureaucratic for the trainees, contributing to the immersion of these future teachers in their job context. It is also possible to observe that the approximation between the subjects of the teaching practice, such as future teachers, teacher trainers and school teachers, allows us to understand the movement of knowledge between university and school. The engagement of everyone involved in the current teaching practice process in a common project opens possibilities for thinking about future proposals for teacher education in real collaboration between both teaching institutions.
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Brown, Patrick J. P. "Anatomy and Physiology: A Guided Inquiry". Digital Commons @ East Tennessee State University, 2015. http://amzn.com/1119175259.

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Students Learn when they are actively engaged and thinking in class. The activities in this book are the primary classroom materials for teaching Anatomy and Physiology, sing the POGIL method. The result is an "I can do this" attitude, increased retention, and a feeling of ownership over the material.
https://dc.etsu.edu/etsu_books/1027/thumbnail.jpg
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Forster, Brenda J. "Piglet blood parameters at birth as indicators of nutritional status and postnatal performance". Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63906.

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Paulet, Julia. "MATURATION OF THE CAROTID BODY OXYGEN-SENSOR DURING RAT DEVELOPMENT". Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1337703804.

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Schulz, Leslie. "Anatomy and Physiology Syllabus for Community Colleges". Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2500/.

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This syllabus includes both lecture notes and laboratory activities for a two-semester anatomy and physiology community college course. The syllabus is based on a 16-week semester that is comprised of a three-hour lecture section and a one-hour laboratory class each week. Both the lecture course and laboratory are necessary to fulfill the requirement for anatomy and physiology. Laboratory activities coincide with lectures to enhance understanding of each topic by providing visual and hands-on experiments for the concepts learned in the lecture. Laboratory quizzes will be given each week to help students maintain a working knowledge of the material learned in the laboratory. This course is appropriate for the typical anatomy and physiology student and should benefit both students who plan to major in biology and also those who are non-biology majors. Because subject matter in anatomy and physiology is quite difficult, the importance of attendance and good study skills is stressed.
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Poscher, Elisabeth. "Salinity Effects on Guayule Leaf Anatomy and Physiology". Diss., The University of Arizona, 2005. http://hdl.handle.net/10150/194362.

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Salinity usually reduces plant growth in terms of height and biomass, but can increase secondary metabolite production. This frequently reported observation in guayule (Parthenium argentatum Gray, Asteraceae) was investigated for possible mechanisms.Osmotic and specific ion effects of four chloride salts (CaCl2, MgCl2, KCl, and NaCl) on leaf anatomical and plant physiological parameters were studied. One-year-old plants of guayule line AZ 2 were grown under two salt concentrations (750 ppm and 1500 ppm) for each salt type (plus a control) in sand culture (semi-hydroponic) for eight weeks under controlled greenhouse conditions in Tucson, Arizona.Growth in height decreased with increasing salt concentration. Shoot dry weight, rubber, and resin contents, however, showed no significant differences between treatments, indicating no effect from either salt concentration or salt type. There was a trend for increasing rubber content with increasing salt concentration, although not statistically significant. At the same time, net CO2 gas exchange rates decreased significantly with increasing salinity.With increasing salt concentration, guayule showed osmotic effects in terms of height, indicating a lower hydraulic conductivity. Although plants of higher salt concentrations utilized significantly less water, they had the same shoot dry weights, rubber, and resin contents. Salt-stressed plants therefore achieved higher water use efficiencies. The diurnal net CO2 gas exchange rates were significantly reduced with increasing salinity; the nocturnal net CO2 gas exchange rates showed no significant difference between the treatments.Anatomically, it was found that the stomata were raised or elevated above the epidermis, and supported by upwardly curving cells. When guayule was grown under salt treatments, the trichomes were found to include deposits of material. Trichomes might act as a detoxification repository for excess ions. Although the physiological significance of raised stomata is unknown, it is hypothesized that the unique combination of raised stomata, indumentum, and multiple layers of palisade parenchyma allows for an overall high photosynthetic capacity and performance. During stress conditions such as salinity or drought, guayule might activate an internal CO2 concentrating mechanism, i.e., bicarbonate/CO2 pump, internal CO2 recycling, or PEP carboxylation activity.
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Willis, Gregory L. "Elucidation of the major histocompatibility system of the pig". Thesis, The University of Sydney, 1985. https://hdl.handle.net/2123/26012.

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This thesis describes a project in which the major histocompatibility system of Australian domestic pigs was elucidated for the first time. Reagents for the serological detection of Class I MHC antigens on lymphocytes were raised by immunizing almost 100 pigs with small pieces of skin taken from the ears of closely related animals. A highly sensitive and reproducible micro-test system was developed for the lymphocyte typing of over 400 pigs and it appeared that at least 10 MHC antigens were defined. In the course of typing these animals, a survey was conducted on the results of over 420 matings to investigate whether a state of histoincompatibility between parents is conducive to reproductive efficiency in this species. No significant trends were revealed from this particular survey, but the project has paved the way for a substantial variety of fascinating future research.
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Sanders, Theresa A. "Quantitation of Teratogenic Effects of 5-fluorouracil Administered to Mice in Vivo or in Submerged Limb Culture". Digital Commons @ East Tennessee State University, 1987. https://dc.etsu.edu/etd/2786.

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This study demonstrates the use of submerged limb culture in teratologic testing. Pregnant mice were treated on day 11 of gestation (E11, plug date = E0) with 10, 20 or 40 mg of 5-fluorouracil (FU) per kg body weight. On E17, treated and untreated fetuses were examined for gross malformations and were fixed in 95% ethanol. Reduction of limb size and digital defects, including ectrodactyly (ED), syndactyly (SD), microdactyly and polydactyly were dose-dependent. In parallel studies, pregnant mice were treated on the morning of E11 and embryos were removed either 7h (E11) or 24h (E12) later for submerged limb culture. Changes in limb area showed a dose-response relationship while treatment had little effect on the shape of individual bones. This indicates the relatively unspecific nature of FU-induced embryotoxicity. E11 studies revealed a dose dependent response of ED, SD and fusion of the metacarpals/metatarsals (MC/MT) to the proximal phalanges. Unlike E11 cultures, middle phalanges were present but decreased in number as dosage increased. Limbs from embryos of untreated females were cultured (E11) in the presence of 0.002, 0.02, 0.2 or 2.0 mg FU/ml culture medium. The percentage of limbs void of paw cartilage or with decreased numbers of MC/MT was dose-dependent. A dose-dependent decrease in the deleterious effects of 0.02 mg FU/ml was observed when 0.2 or 0.02 mg thymine/ml was added to the cultures. In both culture and non-culture studies, hindlimbs (HL) were more affected than forelimbs (FL) and distal regions were more affected than proximal ones. In addition to the morphometric analyses, biochemical parameters of growth and differentiation were examined at 0, 36 and 72h of culture in untreated and treated limbs. Both DNA and protein of FU treated limbs were decreased compared to untreated controls. FL demonstrated greater capacity for regulation of losses in protein content, HL for DNA content. Submerged limb culture provides a useful model for the examination of xenobiotic effects on limb development and allows some comparative evaluation among in vivo, in vivo/in vitro and in vitro studies. (Abstract shortened with permission of author.)
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Wang, Tian. "Developmental physiology of the intestine in neonatal pigs : effects of milk and milk-borne growth factors /". Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20128678.

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Kardegar, Nadia. "Electrical Brain Stimulation and Depressive-like Behavior in Guinea Pigs". Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1342408797.

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Livros sobre o assunto "Anatomy and physiology Swine"

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Symposium on Digestive Physiology in Pigs (8th 2000 Uppsala, Sweden). Digestive physiology of pigs: Proceedings of the 8th Symposium. New York: CABI Pub., 2000.

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2

Sarikas, Stephen N. Laboratory investigations in anatomy & physiology. San Francisco: Pearson Benjamin Cummings, 2007.

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3

Sarikas, Stephen N. Laboratory investigations in anatomy & physiology. 2a ed. San Francisco: Pearson Benjamin Cummings, 2009.

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4

Sarikas, Stephen N. Laboratory investigations in anatomy & physiology. 2a ed. San Francisco: Pearson Benjamin Cummings, 2009.

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5

Marieb, Elaine Nicpon. Human anatomy and physiology: Instructor's guide. Redwood City, Calif: Benjamin/Cummings Pub. Co., 1989.

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6

C, Ober William, e Garrison Claire W, eds. Laboratory manual for anatomy & physiology: Cat version. 4a ed. San Francisco: Pearson Benjamin Cummings, 2010.

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7

C, Ober William, e Garrison Claire W, eds. Laboratory manual for anatomy & physiology: Pig version. 4a ed. San Francisco: Pearson Benjamin Cummings, 2010.

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8

Wood, Michael G. Laboratory manual for anatomy & physiology: Featuring martini art : pig version. Hoboken, New Jersey: Pearson Education, Inc., 2017.

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9

Wood, Michael G. Laboratory manual for anatomy & physiology: Featuring martini art : cat version. Hoboken, New Jersey: Pearson Education, Inc., 2017.

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Donnelly, Patricia J. Laboratory manual for anatomy and physiology, with fetal pig dissections. New York, NY: HarperCollins, 1993.

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Capítulos de livros sobre o assunto "Anatomy and physiology Swine"

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Rocca, Julius. "Anatomy and Physiology". In A Companion to Science, Technology, and Medicine in Ancient Greece and Rome, 343–59. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118373057.ch21.

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Quezada-Euán, José Javier G. "Anatomy and Physiology". In Stingless Bees of Mexico, 57–69. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-77785-6_3.

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De Castro, J., J. Meynadier e M. Zenz. "Anatomy and physiology". In Regional Opioid Analgesia, 19–33. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-009-2321-8_3.

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Soule, James, e William Grierson. "Anatomy and Physiology". In Fresh Citrus Fruits, 1–22. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-8792-3_1.

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Kuehbacher, Tanja. "Anatomy and Physiology". In Inflammatory Bowel Disease Nursing Manual, 3–10. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-75022-4_1.

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Bratinov, Val, e Mark E. Lavallee. "Anatomy and Physiology". In Sports-related Fractures, Dislocations and Trauma, 71–75. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36790-9_7.

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Abrams, Paul. "Anatomy and Physiology". In Urodynamics, 7–16. London: Springer London, 1997. http://dx.doi.org/10.1007/978-1-4471-3598-2_2.

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Lerman, Jerrold, Charles J. Coté e David J. Steward. "Anatomy and Physiology". In Manual of Pediatric Anesthesia, 9–37. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30684-1_2.

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Baguley, David, Gerhard Andersson, Don McFerran e Laurence McKenna. "Anatomy and Physiology". In Tinnitus: A Multidisciplinary Approach, 18–28. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118783009.ch3.

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Nyström, Ernst, Gertrud E. B. Berg, Svante K. G. Jansson, Ove Tørring e Stig V. Valdemarsson. "Anatomy and Physiology". In Thyroid Disease in Adults, 5–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13262-9_2.

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Trabalhos de conferências sobre o assunto "Anatomy and physiology Swine"

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O'Connor, Christopher P. "Anatomy and Physiology of an Agile Transition". In 2011 AGILE Conference. IEEE, 2011. http://dx.doi.org/10.1109/agile.2011.25.

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Chesta, F., D. Inouye e B. Tatsuno. "Tracheal Bronchus: Lobar Collapse Revealing Swine Anatomy". In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1551.

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Mattmann, Chris A., Joshua Garcia, Ivo Krka, Daniel Popescu e Nenad Medvidovic. "The anatomy and physiology of the grid revisited". In 3rd European Conference on Software Architecture (ECSA). IEEE, 2009. http://dx.doi.org/10.1109/wicsa.2009.5290821.

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White, Stephen A., e Karen J. Ousey. "Teaching Anatomy and Physiology Online Using Problem-Based Learning". In 2010 Second International Conference on Mobile, Hybrid, and On-Line Learning (ELML). IEEE, 2010. http://dx.doi.org/10.1109/elml.2010.21.

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Chen, Hui Ju, Zi-Xin You, Yun-Ho Yu, Jen-Ming Chen, Chia-Chun Chang e Chien-Hsing Chou. "Interactive teaching aids design for essentials of anatomy and physiology". In SIGGRAPH '18: Special Interest Group on Computer Graphics and Interactive Techniques Conference. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3230744.3230808.

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Mattmann, Chris A. "A Revisiting of the Anatomy and Physiology of the Grid". In HPDC'15: The 24th International Symposium on High-Performance Parallel and Distributed Computing. New York, NY, USA: ACM, 2015. http://dx.doi.org/10.1145/2753524.2753526.

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"Research on Teaching Reform of Human Anatomy and Physiology Course". In 2018 9th International Symposium on Advanced Education and Management. Clausius Scientific Press, 2019. http://dx.doi.org/10.23977/isaem.2018.015.

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Mohedano-Moriano, Alicia, Domingo Domingo, Sandra Cebada-Sanchez, Maria Carmen Cipriano-Crespo, Jaime Gonzalez-Gonzalez, Olga López-Martín, Silvia Llorens et al. "TEACHING ANATOMY AND PHYSIOLOGY: THE MEETING AS AN INSTRUCTIONAL STRATEGY". In International Technology, Education and Development Conference. IATED, 2016. http://dx.doi.org/10.21125/inted.2016.2047.

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Rangarajan, Divya. "General anatomy and physiology curriculum in high school: A student's perspective". In 2014 IEEE Integrated STEM Education Conference (ISEC). IEEE, 2014. http://dx.doi.org/10.1109/isecon.2014.6891044.

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Han, Jae-Joon, Martin H. Plawecki, Peter C. Doerschuk, Vijay A. Ramchandani e Sean O'Connor. "Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology". In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.259570.

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Relatórios de organizações sobre o assunto "Anatomy and physiology Swine"

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Payne, Theresa. Forms and Functions: Life-Anatomy or Physiology? Portland State University Library, janeiro de 2014. http://dx.doi.org/10.15760/honors.96.

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Sahota, Bill, Sundar Nagarathnam e Tarun Mathur. Implementing Adaptive Technology and Supplemental Curriculum for Anatomy and Physiology. Fort Belvoir, VA: Defense Technical Information Center, outubro de 2002. http://dx.doi.org/10.21236/ada408183.

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Granot, David, e Noel Michelle Holbrook. Role of Fructokinases in the Development and Function of the Vascular System. United States Department of Agriculture, janeiro de 2011. http://dx.doi.org/10.32747/2011.7592125.bard.

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Resumo:
Plant vascular tissues are superhighways whose development and function have profound implications for productivity, yield and stress response. Preliminary studies by the PI indicated that sugar metabolism mediated by fructokinases (FRKs) has a pronounced effect on the transport properties of the xylem. The goal of this research was to determine how the main fructokinase gene, FRK2, and the only plastidic fructokinase, FRK3, influence vascular development and physiology, emphasizing processes that occur at both the cellular and organismic level. We found that both genes are expressed in vascular tissues, but FRK3 is expressed primarily in vascular tissues of mature petioles. Vascular anatomy of plants with antisense suppression of FRK2 uncovered that FRK2 is necessary for xylem and phloem development, most likely due to its role in vascular cell-wall synthesis, and affects vascular development all over the plant. As a result, suppression of FRK2 reduced hydraulic conductivity of roots, stem and leaves and restricted sugar phloem transport. Vascular anatomy of plants with RNAi suppression of FRK3 uncovered that FRK3 is required for vascular development in mature petiole but its role is partially complemented by FRK2. Suppression of FRK3 combined with partial suppression of FRK2 had effects completely different from that of FRK2 suppression, resulting in wilting of mature leaves rather than young leaves of FRK2 suppressed plants, and decreased export of photoassimilates. This primary effect of FRK2 suppression on mature petioles had a secondary effect, reducing the hydraulic conductivity in roots and stem. The very fact that a plastidic fructokinase plays a role in vascular development is quite surprising and we are still seeking to uncover its metabolic mode-of-action. Yet, it is clear that these two fructokinases have different roles in the coordination between photosynthetic capacity and vascular development. We have started analyzing the role of the last third FRK, FRK1, and discovered that it is also expressed exclusively in vascular tissues. It appears therefore, that all FRKs studied here are involved in vascular development. An interesting unexpected outcome of this study was the connection of FRK2 with hormonal regulation of vascular development, most likely auxin. This observation together with the yet to be solved questions on the exact roles of FRK3 are the subjects of our current efforts.
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