Literatura científica selecionada sobre o tema "Acyl-CoAs metabolome"
Crie uma referência precisa em APA, MLA, Chicago, Harvard, e outros estilos
Consulte a lista de atuais artigos, livros, teses, anais de congressos e outras fontes científicas relevantes para o tema "Acyl-CoAs metabolome".
Ao lado de cada fonte na lista de referências, há um botão "Adicionar à bibliografia". Clique e geraremos automaticamente a citação bibliográfica do trabalho escolhido no estilo de citação de que você precisa: APA, MLA, Harvard, Chicago, Vancouver, etc.
Você também pode baixar o texto completo da publicação científica em formato .pdf e ler o resumo do trabalho online se estiver presente nos metadados.
Artigos de revistas sobre o assunto "Acyl-CoAs metabolome"
Tokarska-Schlattner, Malgorzata, Nour Zeaiter, Valérie Cunin, Stéphane Attia, Cécile Meunier, Laurence Kay, Amel Achouri et al. "Multi-Method Quantification of Acetyl-Coenzyme A and Further Acyl-Coenzyme A Species in Normal and Ischemic Rat Liver". International Journal of Molecular Sciences 24, n.º 19 (6 de outubro de 2023): 14957. http://dx.doi.org/10.3390/ijms241914957.
Texto completo da fonteHan, Lijuan, Ling Zhao, Yong Zhou, Chao Yang, Teng Xiong, Lin Lu, Yusheng Deng et al. "Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity". ISME Journal 16, n.º 4 (8 de novembro de 2021): 983–96. http://dx.doi.org/10.1038/s41396-021-01123-5.
Texto completo da fonteIGAL, R. Ariel, Ping WANG e Rosalind A. COLEMAN. "Triacsin C blocks de novo synthesis of glycerolipids and cholesterol esters but not recycling of fatty acid into phospholipid: evidence for functionally separate pools of acyl-CoA". Biochemical Journal 324, n.º 2 (1 de junho de 1997): 529–34. http://dx.doi.org/10.1042/bj3240529.
Texto completo da fontePons, Roser, e Darryl C. De Vivo. "Primary and Secondary Carnitine Deficiency Syndromes". Journal of Child Neurology 10, n.º 2_suppl (novembro de 1995): 2S8–2S24. http://dx.doi.org/10.1177/0883073895010002s03.
Texto completo da fonteYu, Wenfeng, Xiquan Liang, Regina E. Ensenauer, Jerry Vockley, Lawrence Sweetman e Horst Schulz. "Leaky β-Oxidation of atrans-Fatty Acid". Journal of Biological Chemistry 279, n.º 50 (4 de outubro de 2004): 52160–67. http://dx.doi.org/10.1074/jbc.m409640200.
Texto completo da fonteVarner, Erika L., Sophie Trefely, David Bartee, Eliana von Krusenstiern, Luke Izzo, Carmen Bekeova, Roddy S. O'Connor et al. "Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues". Open Biology 10, n.º 9 (setembro de 2020): 200187. http://dx.doi.org/10.1098/rsob.200187.
Texto completo da fonteXia, Chuanwu, Zhuji Fu, Kevin P. Battaile e Jung-Ja P. Kim. "Crystal structure of human mitochondrial trifunctional protein, a fatty acid β-oxidation metabolon". Proceedings of the National Academy of Sciences 116, n.º 13 (8 de março de 2019): 6069–74. http://dx.doi.org/10.1073/pnas.1816317116.
Texto completo da fonteLone, Museer A., Andreas J. Hülsmeier, Essa M. Saied, Gergely Karsai, Christoph Arenz, Arnold von Eckardstein e Thorsten Hornemann. "Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases". Proceedings of the National Academy of Sciences 117, n.º 27 (23 de junho de 2020): 15591–98. http://dx.doi.org/10.1073/pnas.2002391117.
Texto completo da fonteCarrer, Alessandro, Joshua L. D. Parris, Sophie Trefely, Ryan A. Henry, David C. Montgomery, AnnMarie Torres, John M. Viola et al. "Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels". Journal of Biological Chemistry 292, n.º 8 (11 de janeiro de 2017): 3312–22. http://dx.doi.org/10.1074/jbc.m116.750620.
Texto completo da fonteWu, Hao, Jingdan Liang, Lixia Gou, Qiulin Wu, Wei-Jun Liang, Xiufen Zhou, Ian J. Bruce, Zixin Deng e Zhijun Wang. "Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882". Applied and Environmental Microbiology 84, n.º 12 (13 de abril de 2018): e00587-18. http://dx.doi.org/10.1128/aem.00587-18.
Texto completo da fonteTeses / dissertações sobre o assunto "Acyl-CoAs metabolome"
Zeaiter, Nour. "Les effets des changements métaboliques sur le métabolome des acyl-CoAs et l'acylation d'histone épigénétique". Electronic Thesis or Diss., Université Grenoble Alpes, 2024. http://www.theses.fr/2024GRALV013.
Texto completo da fonteAccumulating evidence suggests that metabolism can affect epigenetic post-translational modifications of histones, thus potentially linking nutrient availability or environmental conditions to gene expression and human physiopathology. However, there is still a lack of more detailed insight into this relationship. Here we study the role of short-chain (sc)-acyl-CoAs, generated in various metabolic pathways, as substrates for histone acylation. Analyzing acyl-CoAs is challenging due to their diverging (sub)cellular concentrations and physico-chemical properties. First, we applied a panel of analytical methods to establish reliable acyl-CoAs quantification, using liver ischemia as a model for inducing a metabolic shift. HPLC and MS emerged as the most suitable methods for unbiased analysis of sc-acyl-CoAs. Second, we employed HepG2 cells as a model system to explore the role of metabolic key enzymes and nutrient-induced metabolic shifts on acyl-CoA levels and histone acylation. Here and in the following, sc-acyl-CoAs were quantified by MS, and histone acylation was assessed at H4K5 and H4K8 by immunoblotting. Knockdown (KD) of enzymes involved in nucleocytosolic generation of acetyl-CoA (and potentially other acyl-CoAs) confirmed that ATP citrate lyase (ACLY) and acetyl-CoA synthetase short chain 2 (ACSS2) are the two major sources for nucleo-cytosolic acetyl-CoA. Moreover, we demonstrated that contrary to widespread believe, ACSS2 is not involved in biosynthesis of sc-acyl-CoAs other than acetyl-CoA. Further, KD of carnitine palmitoyltransferase 1A (CPT1A) did not yield clear evidence for its involvement in the export of mitochondrial sc-acyl-CoAs. Among the metabolic shifts studied, changes in acyl-CoA levels correlated with altered histone acylation only in some cases, namely octanoate fatty acid supplementation and glucose deprivation. These data suggest that substrate availability can be a determining factor for histone acylation, but that other factors can also be involved. Third, a transgenerational rat model for the effects of an environmental pollutant, endocrine disruptors (ED), revealed altered histone acylation patterns. Here we developed a HepG2 cell model that recapitulates direct ED effects on histone acylation, in particular an increased level of acetylation, together with increased acetyl-CoA levels. These data suggest HepG2 cells as a suitable model to study epigenetic ED effects mechanistically. In summary, this work established a basis to study epigenetic effects of nutrients and environmental pollutants in more detail
Knoll, Anja. "Etude du métabolisme des acides gras à très longues chaînes dans le cerveau du rat : activités enzymatiques d'élongation des acyl-CoAs, expression des gènes de la béta-oxydation peroxysomale". Bordeaux 2, 2000. http://www.theses.fr/2000BOR28756.
Texto completo da fonte