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1

Millen, James. "A cold strontium Rydberg gas". Thesis, Durham University, 2011. http://etheses.dur.ac.uk/849/.

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Cold gases of Rydberg atoms are an ideal system in which to study the novel effects of strong interatomic interactions. This thesis describes the design and construction of the world's first experiment to study Rydberg states in a cold gas of an alkaline earth metal, in this particular case strontium. We have studied a wide range of Rydberg states, and have developed a sensitive ``step-scan" spectroscopic technique that detects the spontaneous ionization of the Rydberg gas. The step-scan method is used to acquire Stark maps, and these measurements verify a single-electron model for calculating dipole matrix-elements. From the matrix-elements, interaction strengths between strontium Rydberg atoms have been calculated for the first time. The presence of two valence electrons in an alkaline earth metal, such as strontium, offers a new angle on the study of Rydberg atoms. We create doubly excited ``autoionizing" states, the first such study in a cold gas. Autoionization is used as a high yield probe of Rydberg states, and enables a study of excitation dynamics with nanosecond time-resolution. We show that autoionization can quantitatively identify and elucidate state mixing in the Rydberg gas, and probe population transfer at the very onset of ultra-cold plasma formation.
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2

Gregori, Daniele <1975&gt. "Sistema di monitor e controllo della farm on-line e studio del decadimento Bºs → J/Ψ Φ a LHCb". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/849/.

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3

Valverde, Sarah Hatheway. "THE MODERN SEX DOLL-OWNER: A DESCRIPTIVE ANALYSIS". DigitalCommons@CalPoly, 2012. https://digitalcommons.calpoly.edu/theses/849.

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Over the last fifteen years, the sex doll industry has grown from producing inexpensive novelty items to creating a multimillion-dollar global industry featuring high- quality, realistic love dolls. These dolls are designed and advertised for sexual stimulation, companionship, artistic representations of human fantasy, and other creative pursuits, such as photography. Made of flesh-like silicone, modern sex dolls sell from $3,500-$10,000. The use of human simulacra for sexual stimulation is an enduring practice. However, the psychological community has said little on the subject. Early sexologists briefly reference Agalmatophilia or Statuphilia, a rare sexual attachment to statues. Today, the sex doll phenomenon appears increasingly prevalent across the globe. Media coverage of this phenomenon has been featured in online magazines, television programs, music, documentaries and major motion pictures. More often than not, sex doll-ownership is portrayed as pathological. Sex doll-owners are members of a marginalized population, and accessing the population is challenging as many members of the community wish to remain anonymous for fear of judgment, persecution, and psychiatric labeling. The purpose of this study was to increase psychology’s understanding of this interesting and growing population. Specifically, a 45-item online survey addressing demographics was constructed and assessed. Additionally, participants were asked to describe their relationship status, doll-ownership status, and satisfaction with human and sex doll partners, including sexual satisfaction and performance. Quality of life was also assessed via the Satisfaction with Life Scale (SWLS). Sixty-one participants were recruited from an online doll-owner community forum. It was hypothesized that most doll-owners sampled would be middle-aged, White, single, heterosexual males who are neither significantly better nor worse in terms of psycho-sexual functioning and life satisfaction than the general population. Descriptive data and statistical analysis partially supported the hypotheses. Implications and future direction are discussed, as are methodological considerations.
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4

deFreitas, Adrian A. "A Framework to Support Opportunistic Groups in Context-Aware Applications". Research Showcase @ CMU, 2016. http://repository.cmu.edu/dissertations/849.

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Context-aware computing utilizes information about users and/or their environments in order to provide relevant information and services. To date, however, most context-aware applications only take advantage of contexts that can either be produced on the device they are running on, or on external devices that are known beforehand. While there are many application domains where sharing context is useful and/or necessary, creating these applications is currently difficult because there is no easy way for devices to share information without 1) explicitly directing them to do so, or 2) through some form of advanced user coordination (e.g., sharing credentials and/or IP addresses, installing and running the same software). This makes these techniques useful when the need to share context is known a priori, but impractical for the one time, opportunistic encounters which make up the majority of users’ lives. To address this problem, this thesis presents the Group Context Framework (GCF), a software framework that allows devices to form groups and share context with minimal prior coordination. GCF lets devices openly discover and request context from each other. The framework then lets devices intelligently and autonomously forms opportunistic groups and work together without requiring either the application developer or the user to know of these devices beforehand. GCF supports use cases where devices only need to share information once or spontaneously. Additionally, the framework provides standardized mechanisms for applications to collect, store, and share context. This lets devices form groups and work together, even when they are performing logically separate tasks (i.e., running different applications). Through the development of GCF, this thesis identifies the conceptual and software abstractions needed to support opportunistic groups in context-aware applications. As part of our design process, we looked at current contextsharing applications, systems, and frameworks, and developed a conceptual model that identifies the most common conditions that cause users/devices to form a group. We then created a framework that supports grouping across this entire model. Through the creation of four prototype systems, we show how the ability to form opportunistic groups of devices can increase users and devices’ access to timely information and services. Finally, we had 20 developers evaluate GCF, and verified that the framework supports a wide range of existing and novel use cases. Collectively, this thesis demonstrates the utility of opportunistic groups in context-aware computing, and highlights the critical challenges that need to be addressed to make opportunistic context sharing both practical and usable in real-world settings. The contributions of this thesis are: 1. A conceptual model, based on an analysis of prior literature, which describes the conditions under which users and/or devices form and work in groups. 2. An implementation of the Group Context Framework, which highlights the software abstractions and architecture needed to support all of the group types identified in our conceptual model. 3. A demonstration of the value of opportunistic groups in context aware computing, through the creation of four major systems and numerous smaller applications. 4. A validation of GCF’s robustness, through an examination of 65 ideas submitted by 20 developers. 5. An examination of the challenges associated with utilizing opportunistic groups in context-aware applications, based on our own experiences using GCF, as well as from issues raised by developers from academia and industry.
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5

Byrd, Anna. "A Study of State College Faculty Trust in Immediate Supervisors". UNF Digital Commons, 2018. https://digitalcommons.unf.edu/etd/849.

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This quantitative study investigated faculty trust in their immediate supervisors (academic deans and faculty chairs) in a state college setting. A survey instrument created for this study was based on existing research on trust in schools by Bryk and Schneider (2002) and Tschannen-Moran and Hoy (1998), as well as research on trust in corporate setting. The study’s purpose was to determine the types and frequencies of interactions between community college faculty and deans/faculty chairs – i.e., faculty immediate supervisors – that are related to higher levels of faculty trust. Also investigated were the relationships between faculty trust and demographic characteristics including age, gender, ethnicity, length of employment, and number of faculty in department. The study’s findings suggest policies and practices for creating more trusting environments in community and state college settings, thereby leading to higher faculty retention levels. These, in turn, can contribute to increased levels of student success, higher graduation rates, and financial savings for schools.
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6

Buckingham, Judith Isabel. "Patterns of violence in intimate relationships: a critical examination of legal responses". University of Canterbury. Law, 2006. http://hdl.handle.net/10092/849.

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In this thesis, red flags for dangerousness/lethality established from domestic violence and homicide research provided the social framework for an examination of legal responses to violence in intimate heterosexual relationships. The research investigated these gendered, structural patterns of violence and the effectiveness of criminal justice interventions in keeping victims safe. Agency interactions with offenders and victims prior to women's deaths were reviewed in selected cases. Criminal law constructions of violence in intimate relationships were evaluated for their recognition and understanding of primary risk factors for dangerousness/lethality. The research found major red flags remain invisible in criminal law stereotypes of violence between intimates. The significance of these risk factors for dangerousness/lethality is therefore overlooked, misunderstood and even misrepresented in defence of violent offenders. Although the aim of the Domestic Violence Act 1995 is to ensure effective protection for victims, the study found a significant number of women (and sometimes other family members and children) experience further sub-lethal and lethal violence following legal interventions with perpetrators. Lacking a principled policy foundation, central focus on victim safety and clear framework for interventions, legal responses are internally incoherent and inconsistent with New Zealand Family Violence Prevention Strategy. The New Zealand government has committed to principled domestic violence intervention and consistency in law and policy. This will require: a) legislative reform; b) public and professional education on the dynamics of violent relationships, including the interrelationship between sublethal and lethal assaults; and c) monitoring of criminal justice interventions to improve accountability. Until this is accomplished, stories of abused women and their children, including informal attempts to seek help and contact with state and community agencies will continue to be dishonoured by a legal system which silences their voices and fails to learn lessons from their injuries and deaths.
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7

VanOudenhove, Jennifer J. "Mechanisms Regulating Early Mesendodermal Differentiation of Human Embryonic Stem Cells: A Dissertation". eScholarship@UMMS, 2016. http://escholarship.umassmed.edu/gsbs_diss/849.

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Key regulatory events take place at very early stages of human embryonic stem cell (hESC) differentiation to accommodate their ability to differentiate into different lineages; this work examines two separate regulatory events. To investigate precise mechanisms that link alterations in the cell cycle and early differentiation, we examined the initial stages of mesendodermal lineage commitment and observed a cell cycle pause that occurred concurrently with an increase in genes that regulate the G2/M transition, including WEE1. Inhibition of WEE1 prevented the G2 pause. Directed differentiation of hESCs revealed that cells paused during commitment to the endo- and mesodermal, but not ectodermal, lineages. Functionally, WEE1 inhibition during meso- and endodermal differentiation selectively decreased expression of definitive endodermal markers SOX17 and FOXA2. These findings reveal a novel G2 cell cycle pause required for endodermal differentiation. A role for phenotypic transcription factors in very early differentiation is unknown. From a screen of candidate factors during early mesendodermal differentiation, we found that RUNX1 is selectively and transiently up-regulated. Transcriptome and functional analyses upon RUNX1 depletion established a role for RUNX1 in promoting cell motility. In parallel, we discovered a loss of repression for several epithelial genes, indicating that RUNX1 knockdown impaired an epithelial to mesenchymal transition during differentiation. Cell biological and biochemical approaches revealed that RUNX1 depletion compromised TGFβ2 signaling. Both the decrease in motility and deregulated epithelial marker expression upon RUNX1 depletion were rescued by reintroduction of TGFβ2, but not TGFβ1. These findings identify novel roles for RUNX1-TGFβ2 signaling in mesendodermal lineage commitment.
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Hamiter, Amelia. ""It's Not a Real Disorder": Attention Deficit/Hyperactivity Disorder and Paradigms of Childhood Harm". Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/scripps_theses/849.

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Attention Deficit/Hyperactivity Disorder has garnered controversy in the United States since it became a widely diagnosed disorder in American schoolchildren in the 1970s. Both diagnosis and treatment are sites of controversy. Some believe the disorder is a contrivance of parents and teachers who do not want to deal with hardly exceptional childhood difficulties, or a contrivance of pharmaceutical companies taking advantage of such parents and teachers. Others believe that a neurobiological basis for the disorder will eventually be discovered, and thus will legitimize both the diagnosis and the practice of prescribing medication for treatment. I utilize the Science, Technology, and Society approach of actor network theory to show that these multiple understandings of ADHD can coexist, since ADHD is a complex product of external and internal agents. This will demonstrate how cultural shifts and values cause parents, teachers, and doctors to evaluate childhood in a way that frames certain behaviors as harmful. I also evaluate how cultural values of medicalization center issues in the individual rather than in external factors, and assess the values that psychiatric treatment appeals to and whether they primarily serve the needs of children. I conclude that ADHD is a heavily context-dependent disorder, but that that does not delegitimize harmful effect on children who exhibit ADHD-associated behaviors. I also conclude that the current dominant medicalized approach to ADHD is not optimal because it focuses on only a few of the total factors that make ADHD a pathological disorder for children in the contemporary United States.
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9

Fraser, Jeremiah Owen. "The coach-athletic trainer relationship and its association with athletic trainers' job satisfaction : a thesis". Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/849.

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The purpose of this study was to examine if Division I Collegiate Athletic Trainers' (ATs') perceived.quality of their relationship, with a head coach, is associated with total job satisfaction. The study was driven by three questions: 1) Does a correlation exist between ATs' perceptions of the quality of the coach-AT relationship and total job satisfaction? 2) Will either the direct or the meta-perspective held by the AT be significant predictors of overall job satisfaction? and 3) Will ATs' assumed similarity be a significant predictor of overall job satisfaction? In order to examine this issue, ATs assigned to NCAA division I institution's baseball or softball team were given a compendium survey. The survey was composed of the Job Satisfaction Survey (Spector, 1994), a modified Coach-Athlete Relationship Questionnaire (CART-Q) (Jowett & Ntoumanis, 2004), and a modified meta Coach-Athlete Relationship Questionnaire (meta CART-Q). The surveys measured ATs' total job satisfaction.and satisfaction with various job sub factors, and their direct and meta-perspectives of their relationship with their coach, respectively. Correlational and regression analyses were used to determine the influence and predictability of aspects of a quality relationship to total job satisfaction. The findings demonstrate that ATs' perception of the quality of certain aspects of their relationship with a head coach is related to overall job satisfaction. This indicates that greater efforts need to be taken to improve overall coach-AT relationship dynamics. Improving the dynamics is needed to improve conditions that can cause unacceptably low levels of job satisfaction, which lead to burnout and attrition. The quality of the coach-AT relationship and its impact on Job satisfaction needs to be recognized as a contributing factor to AT job satisfaction. Understanding the coach-AT relationship can help direct measures to address decreased job satisfaction levels and stave off attrition in athletic training.
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10

Kamanga, Harris Benula. "The role of governance in using project finance as a contract for the delivery of infrastructure in Africa". Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/849.

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Thesis (MDF (Development Finance))--Stellenbosch University, 2008.
ENGLISH ABSTRACT: Infrastructure has been hailed as a fundamental link between markets and other development sectors of the economy. For over a long time the delivery of infrastructure in Africa has been the domain of the public sector. However, because of the continued budgetary constraints, most governments are seeking the support of the private sector in the delivery of infrastructure. Recent studies have, however, revealed that private participation in infrastructure delivery is very low in Africa. The research noted that certain obstacles at macro level of the economy are responsible for the low private participation in infrastructure delivery. It is, therefore, important that we assess the methodologies that have been used to attract private sector participation in infrastructure delivery in Africa. One method that is gaining popularity in the developing world is the use of project finance. The research study sought to achieve two objectives. The first was to discover whether governance played a significant role in attracting foreign lenders to use project finance in the delivery of infrastructure in Africa. The second objective was to find out, given that governance does matter, which of the governance indicators were important and what their relationship was with loan syndication. The study adopted a quantitative approach using six governance indicators as independent variables. The governance indicators are compiled by a team at the World Bank and these governance indicators are available on the World Bank database. Loan tranches were used as observations for the dependent variable with the data for the tranches originating from loans that were advanced under project finance across Africa covering the period between 1996 and 2006. The multiple regression model also incorporated certain control variables the data for which were collected from various sources. Findings from the research study revealed that governance does matter and is positively related to loan syndication in project finance structures. It was revealed that all six governance indicators exerted a positive influence on loan syndication. The results also revealed that political instability and violence, and control of corruption were statistically insignificant. In addition it was found that rule of law exerted the most positive influence on the composition of loan syndication in project finance structures.
AFRIKAANSE OPSOMMING: Infrastruktuur is al aangeprys as ‘n fundamentele skakel tussen markte en ander ontwikkelingsektore in die ekonomie. Die voorsiening van infrastruktuur in Afrika figureer lank reeds in die openbare sektor, maar as gevolg van die volgehoue begrotingsbeperkinge soek die meeste owerhede die steun van die privaatsektor wat betref die voorsiening van infrastruktuur. Onlangse studies het egter bevind dat private deelname in die aflewering van infrastuktuur in Afrika baie laag is. Die navorsing het aan die lig gebring dat daar sekere struikelblokke op die makrovlak van die ekonomie is wat verantwoordelik is vir die geringe privaat deelname in die voorsiening van infrastruktuur. Derhalwe is dit belangrik om die metodologieë wat gebruik is om privaatsektordeelname ten opsigte van infrastruktuurvoorsiening in Afrika te beoordeel. Een metode wat gewild raak in die Derde Wêreld, is die gebruik van projekfinansiering. Hierdie navorsingstudie probeer om twee doelwitte te bereik. Die eerste doelwit is om uit te vind of staatsbestuur ‘n betekenisvolle rol speel om buitelandse kredietverskaffers te lok om projekfinansiering vir infrastruktuuraflewering in Afrika te gebruik. Die tweede doelwit is om, gegewe staatsbestuur se belangrikheid, te bepaal watter van die staatsbestuuraanwysers belangrik is en wat hul verband met leningsindikasie is. Die studie het ‘n kwantitatiewe benadering gevolg en het ses staatsbestuuraanwysers gebruik as onafhanklike veranderlikes. Die staatsbestuuraanwyser is deur ‘n span van die Wêreldbank opgestel en die staatsbestuuraanwyswers is beskikbaar op die Wêreldbank se databasis. Leningdeel is gebruik as waarnemings vir die afhanklike veranderlike, en die data vir die leningdeel is afkomstig van lenings wat toegestaan is onder projekfinansiering dwarsoor Afrika vir die periode 1996 tot 2006. Die meervoudigeregressiemodel het ook sekere kontroleveranderlikes behels, en die data daarvoor is vanuit verskeie bronne ingewin. Die navorsingstudiebevindinge het aan die lig gebring dat staatsbestuur ter sake is en positief aansluit by die leningsindikasie in projekfinansieringstrukture. Dit het aan die lig gekom dat al ses staatsregeringsaanwysers ‘n positiewe invloed op leningsindikasie uitoefen. Die bevindinge het ook daarop gedui dat politieke onstabiliteit en geweld, en korrupsiebeheer statisties onbeduidend is. Daar is ook bevind dat die oppergesag van die reg die mees positiewe invloed op die samestelling van leningsindikasie in projekfinansieringstruksture uitoefen.
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11

Janse, van Noordwyk H. S. "The development of a scale for the measurement of the perceived importance of the dimensions of apparel store image". Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/849.

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12

Lu, Ping. "Identification of Gon4-like as a factor that is essential for B lymphopoiesis and capable of mediating transcriptional repression". Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/849.

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The B cell population is one of the key components of the adaptive immune system, which protects the host from a tremendous variety of pathogens by producing antibodies. B cells develop from hematopoietic stem cells through a pathway known as B lymphopoiesis. This is a process accompanied by intensive gene expression reprogramming. By the end, genes appropriate for the B lineage are activated and those that are not are continuously repressed. The regulation of lineage gene expression is conferred by a network of transcriptional regulators. Although some key components have been defined, more factors, especially those orchestrating the repression of non-B lineage genes, remain to be identified. Chemically induced mutagenesis is a potent way of identifying genes with critical biological functions. Injection of n-ethyl-n-nitrosourea, a mutagen, has generated a unique point mutation in the mouse Gon4-like (Gon4l) gene that specifically causes a loss of peripheral B cells while maintaining the T cell population. The mutation is therefore named Justy for Just T cells. The goal of this thesis project is to analyze the Justy mice and provide insights into the mechanisms underlying the regulation of B lymphopoiesis. The work presented here demonstrates that the protein encoded by Gon4l is essential for early B lymphopoiesis, which is likely through the repression of non-B lineage genes. Gon4l protein contains conserved domains implicated in transcriptional repression and associates in a complex with the transcriptional repression mediators Yin Yang 1 and Sin3a/HDAC1, after these proteins are transiently expressed in cell lines. When bound to DNA, Gon4l is capable of repressing a nearby promoter and this function correlates with its ability to form a complex. Therefore, these results suggest that Gon4l may function as a transcriptional regulator by employing its associated co-factors in the identified complex. Lastly, a wide spectrum of tumors developed in Justy mice, indicating that Gon4l can also act as a tumor suppressor.
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13

Mashau, Godani Samuel. "Myth as a tool of literary, socio-economic, cultural and political liberation in selected works of Naguib Mahfouz, Ngugi wa Thiong'o and Zakws Mda". Thesis, University of Limpopo (Turfloop Campus), 2011. http://hdl.handle.net/10386/849.

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Dias, Júnior Maurício Vieira. "Uma arquitetura para aprendizagem colaborativa utilizando a integração web e TV digital integrativa". Universidade Federal de Alagoas, 2012. http://repositorio.ufal.br/handle/riufal/849.

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The Interactive Digital TV (TVDi) arises in society as an important resource for the promotion of learning, collaborative mainly, in response to technological developments television, and as a way to attend the need to strengthen education in the world. Given this perception, starting from one of the areas of learning sciences entitled CSCL (Computer-Supported Collaborative Learning), designed a research project, based on collaborative components, the result of which is characterized by an architecture for interaction using the Web and TV digital return channel via online, in order to make lessons more dynamic and virtual classroom learning and facilitate extracurricular student, without sacrificing entertainment medium that television provides the learner in his family and social context. The T-questions proposed environment enables virtual interactions and F2F (face to face), favoring a particular type of blended learning (b-learning) in the environment where the student is inserted, enhancing collaboration in order to motivate him to learn. Thus, in this dissertation, was developed a collaborative architecture combining NCL and LUA languages, with the support of the Brazilian middleware emulator - Ginga, composed of two modules: Web-Teacher-Student and TVDi, designed for the environment of Brazilian Digital TV. The adoption of this proposed work environment as a learning resource in an educational institution can assist and facilitate the teaching-learning process by applying this tool to support distance education and classroom, contributing to the social and digital inclusion through the use this media already so familiar in society.
A TV Digital Interativa (TVDi) surge na sociedade, como um recurso importante para a promoção da aprendizagem, principalmente a colaborativa, em resposta à evolução tecnológica da televisão, e como uma forma de atender à necessidade de fortalecer a educação no mundo. Diante desta percepção, partindo de uma das áreas das ciências da aprendizagem intitulada CSCL (Computer-Supported Collaborative Learning), foi concebido um projeto de pesquisa, fundamentado em componentes colaborativos, cujo resultado é caracterizado por uma arquitetura para interação, utilizando a Web e a TV digital via canal de retorno online, com o objetivo de tornar as aulas virtuais e presenciais mais dinâmicas e facilitar o aprendizado extraclasse do aluno, sem abrir mão do meio de entretenimento que a televisão proporciona ao aprendiz em seu contexto familiar e social. O ambiente T-questions proposto possibilita interações virtuais e F2F (face a face), favorecendo um tipo particular de aprendizagem mista (b-learning) no meio em que o aluno está inserido, potencializando a colaboração a fim de motivá-lo a aprender. Desta forma, nesta dissertação, foi desenvolvida uma arquitetura colaborativa associando as linguagens NCL e LUA, com o apoio do emulador do middleware brasileiro Ginga, composta de dois módulos: Web-Professor e TVDi-Aluno, projetados para o ambiente de TV Digital brasileiro. A adoção do ambiente proposto neste trabalho como um recurso de aprendizagem em uma instituição educacional poderá auxiliar e favorecer no processo ensino-aprendizagem com a aplicação desta ferramenta de apoio a educação a distância e presencial, contribuindo para a inclusão social e digital por meio do uso dessa mídia já tão familiarizada na sociedade.
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Cecchin, Aline Brustulin. "Poetas em "reunião" : o grupo matrícula e a consolidação de um sistema literário regional na serra gaúcha". reponame:Repositório Institucional da UCS, 2014. https://repositorio.ucs.br/handle/11338/849.

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O tema da presente dissertação consiste na investigação acerca da contribuição do Grupo Matrícula para a consolidação de um sistema literário regional na Serra Gaúcha. Ao compreender a literatura como um sistema particular, serão analisados elementos de produção, publicação e circulação em relação ao Grupo. Sob esse viés, fazem parte do sistema escritores, leitores e obras, e também editoras, universidades, livrarias, bibliotecas, análises críticas e outros. Será ainda observado o ambiente literário em que surge a antologia, assim como o ambiente que emerge após a sua publicação. À luz da sociologia da literatura, parte-se da totalidade de um sistema literário e, gradativamente, reduz-se ao sistema literário regional da Serra Gaúcha, para, finalmente, verificar o papel do Grupo Matrícula na consolidação desse sistema. Para tanto, servirão como aporte teórico os estudos sobre região cultural, regionalidades, literatura regional e sistemas literários. Os fatores sociais e culturais específicos de uma região, que agem sobre a produção e recepção da literatura, as instituições que constituem uma paisagem literária regional, assim como as condições de leitura e público literário são elementos investigativos da pesquisa em questão que contribuem para que se compreenda a vida literária na Serra Gaúcha, entre os anos de 1950 e 1980.
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The topic studied in this master’s thesis is the investigation about the contribution of Grupo Matrícula to consolidate a regional literary system in Serra Gaúcha. Understanding the literature like a particular system, elements of production will be analyzed, as the publication, and diffusion in relation to the group. Writers, readers, books, publishing houses, universities, libraries, bookstores, and critical analysis are part of this system. The literary landscape, where the anthology arises, will be observed, and, also, the literary configuration after that. Based on the sociology of literature, this research is firstly developed considering a literary system in its totality, and, gradually, it reduces to the regional literary system in Serra Gaúcha, and, finally, it verifies the role of the Grupo Matrícula in the consolidation of a system. The studies about cultural region, regionalities, regional literature and literary systems will be used as theoretical basis. The social and cultural factors of a region that act on the production and reception of literature, the institutions that constitute a regional literary landscape, and, also, the conditions of reading and the literary public are investigating elements of this work. They contribute to understand the literary life in Serra Gaúcha, between 1950 and 1980.
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Carrilo, Lislei do Carmo Tavares. "A CULTURA REGIONAL NO CINEMA DO RIO GRANDE DO SUL: Filmografia de 1981 a 2001". Universidade Metodista de São Paulo, 2006. http://tede.metodista.br/jspui/handle/tede/849.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico
Through qualitative research, with study of descriptive case on the House of Cinema of Porto Alegre, the aim of the project is to analyze whether the cinema produced in Rio Grande Do Sul, has developed proper, regional characteristics, and to observe whether the Gaúcha regional identity was portraied in the cinematographic productions. The House of Cinema of Porto Alegre is producer and distributor of movies, situated in the city of Porto Alegre/RS, was created in December 1987, by a group of Gauchos filmakers. These ones worked with films since the beginning of years 80, and they still they act in the Brazilian cinematographic market. For this analysis it was opted to a clipping in the filmography between 1981 to 2001, for being this one, according to critics, researchers and directors of cinema of Rio Grande do Sul, a period of adaptations and transformations inside the Gaucho cinema.(AU)
Através de pesquisa qualitativa, com estudo de caso descritivo sobre a Casa de Cinema de Porto Alegre, o objetivo do projeto é analisar se o cinema produzido no Rio Grande do Sul desenvolve características próprias ou regionais e observar se a identidade regional gaúcha é retratada nas produções cinematográficas. A Casa de Cinema de Porto Alegre é uma das maiores empresas produtoras e distribuidoras de cinema do Rio Grande do Sul. Situada na cidade de Porto Alegre/RS, a Casa de Cinema foi criada em dezembro de 1987 por um grupo de cineastas gaúchos. Estes trabalhavam em cinema desde o início dos anos 80, e ainda atuam no mercado cinematográfico brasileiro. Para esta análise, optou-se por um recorte na filmografia entre 1981 a 2001, por ser este, segundo críticos, pesquisadores e diretores de cinema do Rio Grande do Sul, um período de adaptações e transformações dentro do cinema gaúcho.(AU)
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Gregori, Daniele <1975&gt. "Sistema di monitor e controllo della farm on-line e studio del decadimento Bºs → J/Ψ Φ a LHCb". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/849/1/Tesi_Gregori_Daniele.pdf.

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Reaño, Cabrejos Romina. "Inserción de genes cry3Ca1 y cry7Aa1 en Ipomoea batatas (L.) Lam. cv. Huachano para conferir resistencia a Cylas puncticollis y C. brunneus “gorgojos del camote” (Coleoptera: Curculionidae)". Bachelor's thesis, Universidad Ricardo Palma, 2013. http://cybertesis.urp.edu.pe/handle/urp/849.

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Con la finalidad de insertar los genes cry3Ca1 y cry7Aa1 en Ipomoea batatas (L.) Lam. cv. “Huachano” para conferir resistencia a Cylas puncticollis y C. brunneus “gorgojos del camote”, se desarrolló la transformación genética mediada por Agrobacterium tumefaciens, siguiendo dos protocolos de regeneración y transformación. Partiendo de 46 meristemos y 282 hojas con peciolo, se obtuvieron 8 eventos transgénicos de inserción completa del ADN - T (4 por cada protocolo de transformación) y un evento de inserción incompleta. Con una eficiencia de transformación de 8.70%, el protocolo a partir de meristemos demostró ser más eficaz en la obtención de eventos transgénicos de inserciones completas que el protocolo a partir de hojas con peciolo, con el cual se obtuvo una eficiencia de transformación de 1.42%. A su vez, los regenerantes fueron evaluados mediante pruebas in vitro (resistencia a kanamicina) y moleculares (PCR), con los análisis de PCR se confirmó que los 8 regenerantes callo positivos (resistentes a la prueba de kanamicina) también presentaron la inserción de los transgenes de interés “cry3Ca1 y cry7Aa1” y del gen marcador selector “nptII”. Asimismo, se determinó que 4 de los eventos transgénicos integraron secuencias externas al ADN - T “backbone” en el genoma de la planta, uno de los cuales, presentó la inserción del gen bacteriano “virD2”.With the purpose of inserting the genes cry3Ca1 and cry7Aa1 in Ipomoea batatas (L.) Lam. cv. "Huachano" to develop resistance to Cylas puncticollis and C. brunneus “sweet potato weevils”, the genetic transformation was developed using Agrobacterium tumefaciens, following two protocols of regeneration and transformation. Starting from 46 meristems and 282 leaves with petiole, 8 transgenic events were obtained with complete insertion of T - DNA (4 for each transformation protocol) and one event with incomplete insertion. With an efficiency of transformation of 8.70 %, the protocol of meristems proved to be more effective in obtaining transgenic events of complete inserts than the protocol of leaves with petiole, which obtained a efficiency of transformation of 1.42 %. The regenerants were evaluated by testing in vitro (resistance to kanamycin) and molecular (PCR), the PCR analysis confirmed that the 8 regenerants positive callus (resistant to kanamycin test) also presented the insertion of transgenes of interest “cry3Ca1 and cry7Aa1” and selection marker gene “nptII”. Likewise, 4 of the transgenic events integrated sequences outside the T - DNA “backbone” into the plant genome, one of whom, showed the insertion of the bacterial gene “virD2”.
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Pedersen, Anja Panduro. "Jumping the tracks : capability of employeeship during a strategic change". Thesis, Blekinge Tekniska Högskola, Institutionen för industriell ekonomi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-849.

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Employeeship is a growing organizational resource. Yet many organizations forget to focus on their employees during change processes. In modern society change has become an inherent feature in most organizations and employees are expected to be competent and adapt. They are expected to maintain their capability of practising employeeship during changes. The study aimed at gaining an understanding of how employees experience their capability of employeeship during a strategic organizational change. The study built on a recent development in Denmark as changes where implemented in the Danish public school system. Building on theories about employee capability and employeeship the study examined how teachers experienced their own capability of adapting to and performing during changes. The study examined how employees experience their own employeeship. To analyse the experienced employeeship a qualitative study was carried out with semi-structured interviews of six public school teachers. A hermeneutic approach was applied to the study in order to gain a holistic understanding of the experienced capability of employeeship. The result shows that strategic changes in organizations not only involves changes to organizational structures. It also involves changes to how employees experience their own capability of employeeship. It changes the balance of their lived worlds.
Medarbetarskap är en växande resurs inom organisationer. Ändå glömmer många organisationer att fokusera på medarbetarna i förändringsprocesser. I det moderna samhället är förändring nu mer en naturlig del av organisationer och medarbetarna förväntas vara kompetenta och anpassa sig. De förväntas upprätthålla förmågan att utöva medarbetarskap under en förändring. Studien syftar att uppnå förståelse för hur medarbetarna själva uppfattar förmågan till medarbetarskap under en strategisk förändring i en organisation. Studien baserades på en nyligen genomförd utveckling i Danmark där nya reformer implementerats i den danska grundskolan. Teorier om medarbetarförmåga och medarbetarskap ligger som grund till studien som undersökte hur lärare uppfattar den egna förmågan att anpassa sig och utföra arbetet under en förändringsprocess. Studien undersökte hur medarbetare uppfattar det egna medarbetarskapet. För att analysera uppfattningen av medarbetarskap användes en kvalitativ metod och halvstruktuerade intervjuer med sex grundskolelärare. Studien har en hermeneutisk ansats för att uppnå helhetsförståelse av uppfattningarna. Resultaten visade att strategiska förändringar i organisationer inte enbart medför ändringar på organisationens struktur: utan även förändringar av hur medarbetarna uppfattar den egna förmågan av medarbetarskap. Det förändrar hur de uppfattar balansen i sin livsvärld.
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Lourenço, Gilclécia Oliveira. "Filhos/as de casais do mesmo sexo : como representam a si mesmo/as e a suas famílias". Universidade Católica de Pernambuco, 2013. http://www.unicap.br/tede//tde_busca/arquivo.php?codArquivo=849.

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DELFINO, Denizard André de Abreu. "Investigação epidemiológica de epizootia de febre amarela em primatas não-humanos em Goiás, no período de 2007 a 2010". Universidade Federal de Goiás, 2011. http://repositorio.bc.ufg.br/tede/handle/tde/849.

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The objective of this study was to carry out and analyze the actions taken to control the yellow fever epizootic in non-human primates, recorded in November 2007 to March 2010 in Aparecida de Goiania, Goias Brazil. The primary epidemiological information on the disease was obtained from the Municipal Health Secretariat, by the local Center for Zoonosis Control. Data were analyzed from the outbreak reports. In A descriptive study, the control actions, such as blocking vaccine against yellow fever by the municipal health department and the evaluation of physical barriers to contain the virus, were verified. The inspection of 58 dead nonhuman primates, representing 100% of the animals found in the period previously mentioned, was used. From these, 34.48% (20/58) were able to have samples collected, according to the specifications of the Epizooty Handbook Of this amount (58), 27.59% (16/58) of monkeys were collected and3.45% (2/58) presented positivity for yellow fever virus. By evaluating the actions that contributed to the epidemiological assessment at the city, it is emphasized the occurrence of three deaths among genera and species of nonhuman primates, Alouatta caraya, Cebus apella and Callithrix spp, with the circulation of yellow fever virus in two cities with epidemiological distinct characteristics. The areas which showed the highest incidence of deaths of monkeys had also the greatest degree of urban growth, characterized by recent environmental changes and residual maintenance of natural areas.
O presente estudo constituiu na condução e análises de ações desenvolvidas no controle da epizootia de febre amarela em primatas não-humanos, registrada nos meses de novembro 2007 a março de 2010 em Aparecida de Goiânia, Goiás. As informações epidemiológicas primárias relativas à enfermidade foram obtidas junto à Secretaria Municipal de Saúde, pelo Centro de Controle de Zoonoses local. A partir das fichas de notificação para epizootia os dados foram analisados. Foi realizado estudo descritivo, que estudou as ações de controle, como bloqueio vacinal contra a FA pela secretaria municipal de saúde do município e a avaliação das barreiras físicas na contenção do vírus amarílico. Foi utilizada a inspeção de 58 primatas não-humanos mortos, que representaram 100% dos animais encontrados no período acima citado, sendo que destes 34,48% (20/58) estavam aptos para colheita de amostras, segundo as especificações do com o Manual de Epizootia. Deste montante, foram coletados 27,59% (16/58) de macacos, com uma positividade para o vírus amarílico de 3,45% (2/58). Avaliando as ações que contribuíram para realização da investigação epidemiológica no município, destaca-se que ocorreram mortes entre três gêneros e espécies de primatas não-humanos, Alouatta caraya, Cebus spp. e Callithrix spp., com a circulação do vírus da FA em duas localidades com características epidemiológicas distintas. As áreas de maior ocorrência de mortes de macacos foram aquelas com maior grau de antropização, caracterizadas por alterações ambientais recentes e manutenção residual de áreas naturais.
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Amador, Josy Ramos de Oliveira. "A prática do serviço social no plantão: análise da inserção profissional na seguridade social em Bom Jesus do Itabapoana/RJ". Universidade do Estado do Rio de Janeiro, 2008. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=849.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
O presente trabalho analisa a realidade do plantão do Serviço Social no âmbito da seguridade social, no Município de Bom Jesus do Itabapoana/RJ, tendo como referência o projeto ético-político profissional do Serviço Social, expresso no Código de Ética profissional, na lei que regulamenta a profissão, bem como nas diretrizes curriculares da ABEPSS. A partir deste projeto, entendemos o plantão como um espaço de atuação desafiante para os profissionais comprometidos com a construção de práticas democráticas e coletivas de atendimento às demandas no contexto institucional. Assim, o objetivo do presente trabalho foi o de analisar teoricamente o espaço do plantão, buscando verificar se os assistentes sociais utilizam o referencial teórico crítico-dialético presente na produção do Serviço Social, para pensar alternativas no espaço cotidiano do plantão, buscando o desenvolvimento de práticas coletivas e não apenas individualistas no atendimento às demandas. O estudo mostrou que a maioria dos assistentes sociais defende os direitos sociais, no entanto, esta defesa não se materializa em ações, no cotidiano profissional, que fortaleçam e favoreçam os usuários no acesso aos serviços na saúde, na previdência e na assistência, como direitos sociais.
This study analyzes the reality of Social Work duty period in the social security system area, in Bom Jesus do Itabapoana/RJ, having the Social Work professional political ethical project as reference, stated in the Professional Ethic Code, in the Law that rules the profession and also in the ABEPSS curricular guidelines. From this project, we can see duty period as a place for challenging acting to the professionals committed with building democratic and collective care practices in the institutional context. Thus, the purpose of this study was to analyse theorically the duty period place, searching for verifying if Social Workers make use of the theoretical critical dialectic reference present in the Social Work literature in order to think about alternatives in the duty period daily place, looking for the development of collective practices and not only individualists in the care demands. This study showed that the majority of Social Workers defend Social Rights however, these discourses arent turned into actions which fortify and favor users to access the health, providence and assistance, as social rights.
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Diehl, Liciane. "Conhecimento de professores sobre a S?ndrome de Burnout : processo, fatores de risco e consequ?ncias". Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2014. http://tede2.pucrs.br/tede2/handle/tede/849.

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The Burnout Syndrome (BS) has been considered one of the most important occupational health problems of psychosocial character in society. Severity among teaching professionals puts the teaching activity as one of the high-risk professions, in view of the individual, institutional and social repercussions. This dissertation consists of two empirical studies of qualitative design and set out to explore the knowledge of teachers about the Burnout Syndrome, as well as understand the factors used to interpret this process. The I study, titled "Burnout Syndrome: indicators for the construction of a diagnosis", aimed at understanding and identify, through detailed and systematic information, within a real life context, the elements that characterize the BS. Still, we tried to check the signs that characterize the process of diagnosis of BS from the categories Illusion at Work, Wear Psychological Indolence and Guilt, dimensions of BS related to the theoretical model proposed by Gil-Hill (2005). The II study, " Knowledge about Teacher Burnout Syndrome: process, risk factors and consequences", intended for knowledge about Burnout, its symptoms, its development process, risk factors, consequences and possibilities of intervention and investigated the meaning of teaching from the perspective of the teacher, with participation of six teachers of elementary school. From the first study, it was possible to identify elements that form the four dimensions of the theoretical model and the presence of indicators of profile 1, which, added to the sense of guilt, indicate the presence of indicators that characterize the profile 2, more severe clinical picture Burnout. Effective measures taken by the respondent prevented the occurrence of burnout and quitting the profession. The II study results showed is still incipient their understanding of BS, complicating diagnosis and treatment. Pointed out the need for clarification on the signs and symptoms of BS to the worker, as well as healthcare professionals, to the correct diagnosis. Recommendations are also thinking and planning effective intervention measures especially informative about their risk factors, possible expulsion for treatment and financial compensation.
A S?ndrome de Burnout (SB) tem sido considerada um dos agravos ocupacionais de car?ter psicossocial mais importantes na sociedade. Sua severidade entre os profissionais de ensino coloca a atividade docente como uma das profiss?es de alto risco, tendo em vista as repercuss?es individuais, institucionais e sociais. Esta disserta??o constitui-se de dois estudos emp?ricos de delineamento qualitativo e pretendeu explorar o conhecimento de professores sobre a S?ndrome de Burnout, assim como compreender os elementos utilizados para interpretar esse processo. O estudo I, intitulado S?ndrome de Burnout: indicadores para a constru??o de um diagn?stico, teve como objetivo compreender e identificar, por meio de informa??es detalhadas e sistem?ticas, dentro de um contexto de vida real, os elementos que caracterizam a SB. Ainda, buscou-se verificar os sinais que caracterizam o processo de diagn?stico da SB a partir das categorias Ilus?o pelo Trabalho, Desgaste Psicol?gico, Indol?ncia e Culpa, dimens?es da SB relacionadas ao modelo te?rico proposto por Gil-Monte (2005). O estudo II, Conhecimento de Professores sobre a S?ndrome de Burnout: processo, fatores de risco e consequ?ncias, pretendeu verificar o conhecimento sobre Burnout, seus sintomas, seu processo de desenvolvimento, fatores de risco, suas consequ?ncias e possibilidades de interven??o, bem como investigou o significado do trabalho docente sob a perspectiva do professor, tendo como participantes seis professoras de ensino fundamental. A partir do primeiro estudo, foi poss?vel identificar elementos que configuram as quatro dimens?es do modelo te?rico adotado e a presen?a de indicadores do perfil 1, que, acrescidos do sentimento de culpa, indicam a presen?a de indicadores que caracterizam o perfil 2, quadro cl?nico mais severo de Burnout. Medidas efetivas adotadas pela entrevistada impediram a ocorr?ncia do Burnout e desist?ncia da profiss?o. Os resultados do estudo II apontaram ser ainda incipiente a sua compreens?o da SB, dificultando o diagn?stico e adequado tratamento. Aponta-se a necessidade de esclarecimento sobre os sintomas e sinais da SB ao trabalhador, assim como aos profissionais de sa?de, para seu correto diagn?stico. Orienta-se tamb?m pensar e planejar medidas de interven??o eficazes principalmente informativas sobre seus fatores de risco, possibilidades de afastamento para tratamento e compensa??o financeira.
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24

Graham, Zachary. "Numerical simulation of fracture of a nano-paper coated e-glass/polyester composite with thermal damage". Honors in the Major Thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/849.

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Aerospace research for next-generation travel increasingly focuses on the use of advanced composites to reduce weight and cost while retaining strength. One subset of materials with great potential is based on the combination of resin matrix and glass-fiber reinforcement. This research explores the application of a candidate nanopaper coating with a given composite. Prior research applied a set of given heat fluxes to the top surface of the composite for a set of given periods of time, and subsequently performed a 3-point flexural test to determine the elastic modulus for both the coated and uncoated composite for all of the combinations of heat flux and time. A finite element (FE) model is developed using the ANSYS general purpose finite element analysis (FEA) software that models the degradation in strength/stiffness properties based on heating condition and with the goal of predicting cracking using the element death feature in ANSYS. This thesis describes the prior research suggesting both the need for and novelty of this model, and the procedures used to form the model. The loading conditions of the 3-point flexural test are replicated, and four measures of accuracy are developed based on the force versus displacement curve of the test and the FE model. It is envisioned that continuum-level models developed as a part of these research be applied for design of next-generation space components These measurements are used to verify the FE model, and this model is then employed to extrapolate beyond the context of experimental conditions.
B.S.M.E.
Bachelors
Mechanical, Material and Aerospace Engineering
Engineering and Computer Science
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25

Enhamre, Sebastian. "Franz Schubert: Sonat i a-moll, D 845 - En tolkning". Thesis, Kungl. Musikhögskolan, Institutionen för klassisk musik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-3459.

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Denna kandidatuppsats handlar om den österrikiske tonsättaren Franz Schubert (1797 - 1828) och hans pianosonat i a-moll, D 845. Mer specifikt har sonaten i fråga analyserats, med syftet att göra en tolkning av den i synnerhet och Franz Schuberts konstnärskap i allmänhet, utifrån ett perspektiv där Schuberts roll och relation till musikhistorien och idéhistorien undersöks. För att få bättre förståelse för musiken har Schuberts liv, samt några av hans sånger och idéer som kan ha påverkat honom, studerats. Jag har även gjort en analys av verkets fyra satser, där jag tittat på sonatens genomgående teman och motiv. På så sätt har jag försökt tolka musikens underliggande mening. Förhoppningen är att kunna skapa inblick i Schuberts mänskliga erfarenhet och en medvetenhet om vad han vill säga med sin musik, samt att detta ska hjälpa mig i min förståelse och tolkning av musiken. Intentionen är också att det ska vara till hjälp för alla som önskar ta del av Schuberts musik mer på djupet eller låta sig inspireras av den. Resultatet av undersökningen har inneburit en djupare förståelse för Schuberts musik, och i synnerhet för just denna sonat.
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魏宇昌 e Yu-cheong Ngai. "A critical study of Li Shen's (772/773-846) poetic works". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31221543.

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BENSID, REDA. "Autosondages propres intermittents : a propos de 84 observations". Lille 2, 1991. http://www.theses.fr/1991LIL2M206.

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Hugues, Pierre. "Traumatisme des canalicules lacrymaux : a propos de 84 observations". Lille 2, 1989. http://www.theses.fr/1989LIL2M083.

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Gomez, Jean-Marie. "Representation ideale du voyageur par les voyageurs internationaux francais : a propos d'une enquete touchant 847 personnes". Toulouse 3, 1994. http://www.theses.fr/1994TOU31055.

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El, Sahili Abbas. "Caractérisation structurale et fonctionnelle de l’opéron acc chez Agrobacterium tumefaciens C58". Thesis, Paris 11, 2015. http://www.theses.fr/2015PA114829.

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Agrobacterium tumefaciens est une bactérie du sol responsable de la galle du collet chez les plantes lorsqu'elle possède le plasmide Ti (Tumor inducing) dit de virulence (pTi). La bactérie transfère un morceau d’ADN du pTi dans le génome de la plante qui code d'une part la production d’hormones de plantes, à l’origine de la formation de tumeurs colonisées par les bactéries et d'autre part la production de petites molécules (opines) qui servent de nutriment à A. tumefaciens. L'opine, agrocinopine A induit la production de signaux quorum sensing à l’origine de la dissémination du plasmide de virulence vers des bactéries non pathogènes. Agrobacterium radiobacter K84, une bactérie non pathogène, produit de l’agrocine 84, un antibiotique qui tue A. tumefaciens.L’import et le catabolisme de l’agrocinopine A sont réalisés par l’opéron acc présent sur le pTi. La protéine périplasmique (PBP) AccA associée à un transporteur ABC importe l’opine dans le cytoplasme qui est ensuite dégradée par AccF et AccG. AccR régule l’expression de l’opéron acc et celle du facteur de transcription TraR, central dans la signalisation quorum sensing. AccA importe l’agrocine 84 qui est activée par AccF. Mon travail de doctorat a permis par des études structure-fonction de caractériser la spécificité d'AccA et d’AccF et d’initier l’étude du facteur de transcription AccR. L’étude structurale de la PBP en complexe avec l’agrocinopine A, l’agrocine 84 et des dérivés de ces molécules a révélé que seul le motif pyranose-2-phosphate commun aux 2 molécules était reconnu par AccA. Cela a été confirmé par microcalorimétrie et autofluorescence. Le motif pyranose-2-phosphate permettrait donc l’entrée de toute molécule qui le possède à une extrémité. La structure de l’enzyme AccF a montré que là encore seul le groupement pyranose-2-phosphate est reconnu. A partir de la structure obtenue et de modélisation du substrat dans le site actif, un mécanisme enzymatique original pour l’hydrolyse de la liaison phosphodiester est proposé. Les mesures d’affinité par microcalorimétrie montrent que seuls l’arabinose-2-phosphate et le glucose-2-phosphate sont capables de fixer AccR. Des expériences in cellulo ont confirmé qu'ils régulent bien l'expression du QS.Mes travaux apportent un éclairage nouveau sur l’import et l'utilisation de l’agrocinopine chez A. tumefaciens. La spécificité de reconnaissance de la PBP pour une partie de la molécule importée est observée chez d’autres PBP, et ouvre la voie à la conception de molécules antibiotiques qui, à l’image de l’agrocine 84, utilisent une stratégie de type « cheval de Troie »
Agrobacterium tumefaciens is a soil bacterium responsible of the crown gall in plants when it possesses the Tumor inducing plasmid (pTi) which is also the virulence plasmid. The bacterium transfers a piece of DNA from the pTi into the plant genome. The transferred DNA codes for plant hormone synthesis, leading to the formation of tumors which are colonized by bacteria, on one hand, and on the other hand, for the synthesis of small molecules (opines) that are used as nutrients by A. tumefaciens. The opine agrocinopine A induces the production of quorum sensing signals responsible for the spread of the virulence plasmid from pathogenic to nonpathogenic bacterium. Agrobacterium radiobacter K84, a nonpathogenic bacterium, produces the agrocin 84, an antibiotic that kills A. tumefaciens.Import and catabolism of agrocinopine A are operated by acc operon, present on the pTi. The periplasmic binding protein AccA (PBP AccA) associated with the ABC transporter imports the opine into the periplasm where it is degraded by AccF and AccG. AccR regulates the expression of the acc operon and that of the transcription factor TraR, central in quorum sensing signaling. AccA also imports agrocin 84, which is activated by AccF. My PhD work focused on AccA and AccF specificity through structure-function studies and I initiated the study of the transcription factor AccR. The structural study of AccA in complex with agrocinopine A, agrocin 84 and derivatives from these molecules revealed that only the pyranose-2-phosphate motif, common in these two molecules, was recognized. Microcalorimetry and autofluorescence measurements confirmed this conclusion. The pyranose-2-phosphate motif would allow any compound possessing this motif at one end to be transported. The structure of the enzyme AccF showed that again only the pyranose-2-phosphate group is recognized. From the structure and molecular modelling of the substrate in the active site, an original mechanism of the phosphodiester bond cleavage is proposed. Microcalorimetry affinity measures showed that only the arabinose-2-phosphate and glucose-2-phosphate are capable of interacting with AccR. In cellulo experiments confirm that both compounds regulate the expression of quorum sensing.My work sheds light on import and use of agrocinopine in A. tumefaciens. Recognition specificity of the PBP AccA for a part of the imported molecule is observed in other PBPs and opens new ways for rational design of antibiotic compounds that, similarly to agrocin 84, would use the “Trojan horse” strategy
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31

Charlier, Caroline. "Quatre-vingt-quatre - 84 - synoviorthèses de coxités a l'acide osmique". Nantes, 1994. http://www.theses.fr/1994NANT239M.

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BURTIN, GILLES. "Savoir reconnaitre une fievre medicamenteuse : a propos de 84 cas". Nice, 1990. http://www.theses.fr/1990NICE6562.

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DORDAIN, STIVALET ANNE. "Contribution a l'etude du kyste branchial du cou : a partir de 84 observations". Lyon 1, 1989. http://www.theses.fr/1989LYO1M132.

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34

Ghani, E. "Money and the real economy : A study of India 1960-84". Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381844.

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35

Guedes, Gonçalo Miguel Carvalho. "Classificação das locações na McDonald´s Portugal : transição para a norma ASC 842, mudanças e impacto no relato financeiro". Master's thesis, Instituto Superior de Economia e Gestão, 2019. http://hdl.handle.net/10400.5/19731.

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Mestrado em Contabilidade, Fiscalidade e Finanças Empresariais
A partir de 1 de janeiro de 2019, as novas normas contabilísticas relativas aos contratos de locação do IASB (IFRS 16) e do FASB (ASC 842) exigiram que praticamente todas as locações fossem reconhecidas no balanço, como ativo (direito de uso) e passivo (dever de pagamento), sendo previamente testados e classificados como operacionais ou financeiros. A Sistemas McDonald's Portugal, Lda., reporta com base em dois normativos: o local (SNC) e o americano (US GAAP). Como tal, foi obrigada a alterar a forma de contabilização dos seus contratos de locação neste último normativo. Este projeto teve como objetivo entender quais as principais alterações ao nível contabilístico e de processos, como consequência da adoção da norma ASC 842, bem como analisar o impacto da mesma nas demonstrações financeiras da empresa no primeiro semestre de 2019. A empresa teve a necessidade de ajustar os processos existentes para corresponder às exigências da nova norma. A aplicação desta norma teve um grande impacto quer no balanço, onde ocorreu um grande incremento do ativo e do passivo, quer na demonstração de resultados onde a empresa registou um gasto superior com as locações, ao contrário do que aconteceria se se regesse pelo normativo anterior. Também os rácios de Autonomia Financeira e Rentabilidade Operacional dos Ativos foram afetados negativamente.
Since January 1st 2019, the new accounting standards for lease agreements from IASB (IFRS 16) and FASB (ASC 842) required all leases to be recognized in the balance sheet as assets (right of use) and liabilities (payment obligation), being previously tested and classified as operational or financial. Sistemas McDonald's Portugal reports based on two accounting standards: local (SNC) and US (US GAAP). As such, it was required to change the way its lease agreements were accounted for in US book (US GAAP). This project aimed to understand the main accounting and process changes, as a result of the adoption of ASC 842, as well as to analyze its impact on the company's financial statements in the first half of 2019. The company had to adjust existing processes to meet the requirements of the new standard. This application had a great impact both on the balance sheet, where there was a large increase in assets and liabilities, and in the income statement where the company recorded a higher expense with leases than in the old standard. Also the Financial Autonomy and Operating Return on Assets ratios were negatively affected.
info:eu-repo/semantics/publishedVersion
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36

MORIN, CHANTAL. "Resultats a long terme des traitements par l'hormone de croissance : a propos de 84 cas". Toulouse 3, 1992. http://www.theses.fr/1992TOU31078.

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Vieira, Flávio Vilela. "A fratura histórica entre ajuste externo e estabilização: a economia brasileira no período 83-84". reponame:Repositório Institucional do FGV, 1992. http://hdl.handle.net/10438/5467.

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Procura analisar o último programa convencional de ajuste externo e estabilização implementado na economia brasileira em 83/84, no intuito de apreender suas características comportamenteias mais relevantes, para que a partir disso se possa fazer um diagnóstico fundamentado tanto o embasamento teórico, como na análise das variáveis macroeconômicas fundamentais no período referido
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38

VAN, DIJK FREDERIC. "Conception, elaboration sous controle optique en temps reel, fabrication et caracterisation de lasers a cavite verticale emettant par la surface (vcsels) a 840 nm". Toulouse, INSA, 1999. http://www.theses.fr/1999ISAT0035.

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Nous decrivons tout d'abord le comportement optique des elements cle d'un vcsel que sont les miroirs de bragg et la microcavite, et le formalisme d'abeles qui en permet la modelisation. Nous precisons les parametres qui determinent les caracteristiques de ces composants. Nous detaillons les moyens que nous avons mis en uvre pour elaborer des vcsels performants, ce qui necessite une uniformite et une precision sur les epaisseurs extreme. Nous presentons tout d'abord la technique d'epitaxie par jets moleculaires et les conditions de croissance que nous avons optimisees. Nous precisons ensuite la geometrie particuliere que nous avons adoptee afin de garantir l'uniformite en epaisseur des couches epitaxiees et le controle en temps reel par reflectometrie dynamique accordable que nous avons exploite pour obtenir la precision en epaisseur requise pour les vcsels. Nous detaillons alors l'etude que nous avons menee en nous appuyant sur la litterature, pour obtenir des miroirs de bragg dopes de faible resistivite. Nous avons etudie les solutions permettant d'attenuer les effets d'heterojonction et la diffusion du dopant be (p). Nous presentons ensuite les techniques de fabrication qui ont ete developpees pour les vcsels et detaillons alors les differentes etapes technologiques necessaires a la fabrication de composants de type mesa que nous avons choisie en insistant sur l'etape de planarisation que nous avons mise au point. Nous discutons les conditions d'obtention d'un diaphragme dielectrique par oxydation humide selective d'une couche d'alas que nous avons introduit dans certains composants vcsels pour en ameliorer encore les performances. Enfin, nous presentons les resultats des caracterisations des composants que nous avons fabriques : la longueur d'emission laser est respectee avec une precision de 2&, la densite de courant seuil laser inferieure a 600 acm - 2, et la presence d'un diaphragme alox reduit le courant de seuil laser a des valeurs tres inferieures a 1ma.
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39

Araújo, Marcos Octávio Doria de. "Contrato de gestão hospitalar implantado no Estado de São Paulo, sob a égide da lei complementar n. 846, de 04.06.98". reponame:Repositório Institucional do FGV, 2008. http://hdl.handle.net/10438/7990.

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O presente trabalho tem por objetivo o estudo da aplicação do contrato de gestão hospitalar, implantado no Estado de São Paulo, sob a égide da Lei Complementar n. 846, de 04.06.98, tomando-se por base os seguintes aspectos: a) planejamento; b) convocação e processamento dos planos operacionais dos interessados; c) dispensa de licitação para contratação direta com organização social de saúde; d) contrato de gestão em si, suas cláusulas; e) controle público, interno e externo, f) características gerais dessa contratação; g) publicações dos atos; h) assessoria jurídica. Ao final, apresentamos as nossas sugestões para aprimoramento do modelo legal estudado, como, por exemplo, a adoção de medidas visando a ampliação de possíveis interessados na celebração do contrato, a concentração de prazos, sua padronização, e dilatação, além do estabelecimento de exigências relativas às condições econômicas e, especialmente, técnicas, de forma a se assegurar a boa execução contratual, tudo, no fundo, com o desiderato acadêmico de alguma forma contribuir com a Administração Pública brasileira.
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40

Destefanis, Sergio. "The macroeconomic analysis of wage indexation : a case study for Italy, 1963-84". Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239730.

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BERNARD, DOMINIQUE. "La pericardoscopie : a propos des 84 premieres pericardoscopies realisees au c.h.r. de lille". Lille 2, 1991. http://www.theses.fr/1991LIL2M122.

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Hébert, Christophe. "Pantalon anti-choc : experience b.m.p.-s.a.m.u. 84 de janvier 1989 a juin 1991". Aix-Marseille 2, 1992. http://www.theses.fr/1992AIX20047.

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Goraieb, Simone Miranda. "Comportamento do primeiro molar permanente inferior, em crianças brasileiras com 24 a 84 meses". [s.n.], 1992. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290358.

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Orientador: Antonio Carlos Usberti
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: A autora buscou através dessa pesquisa verificar o com¬portamento do primeiro molar permanente inferior, em crianças brasileiras, leucodermas, de 24 a 84 meses de idade, portadoras de oclusão normal. Com base nos resultados obtidos, verificou que o relacionamento angular do longo eixo do primeiro molar permanente inferior com a base mandibular aumentou com a idade, assim como o ângulo formado por este dente com o plano oclusal e o segundo molar decíduo inferior. Já o ângulo formado com o bordo anterior da mandíbula diminuiu com a idade. No relacionamento angular das cúspides vestibulares do primeiro molar permanente inferior com o plano oclusal observou-se uma tendência à diminuição com o aumento da idade devido à curva ascendente descrita por este dente durante a sua irrupção, sendo que esta diminuição angular com ,o aumento da idade foi verificada no relacionamento entre as cúspides e a base mandibular, assim como o bordo anterior da mandíbula. Devido a verticalização deste dente durante o processo eruptivo, o ângulo formado entre as cúspides deste molar com a linha mais distal do segundo molar decíduo inferior aumentou com a idade. Quanto às relações lineares, verificou-se uma diminuição da distância da porção mais mesial do primeiro molar permanente inferior e a distância mais distal do segundo molar decíduo inferior, porém não houve contato entre estes dentes antes que entrassem em oclusão. Na comparação dos métodos para determinação dos estágios De desenvolvimento dentário verificou-se uma coincidência nos resultados
Abstract: This search has the purpose to check the i irst lower permanent molar environment in Brazilian white children normal occlusion, with 24 to 84 months oi age. Our results showed that the angular relationship of the First lower permanent molar axis with the mandibular base increased with age like this long axis teeth angle and the occlusal plane, and with the second lower deciduous molar. The angle established with the anterior border of mandible has decreased with age. The angular relationship of vestibular cuspids of first lower permanent molar with the occlusal plane has decreased with age because this teeth described an ascendent curve in eruption. The same decrease was observed in the relation of this cuspids And the mandibular base and so wi th the anterior border of mandible. We observed a verticalization of this teeth during the eruption because the angle of the cuspids of this molar with the distal line oi second deciduous molar increased. We noted that the distal line of second deciduous molar and the mesial line first lower permanent molar distance decreased with age, but the contact was not established while the teeth was in occlusion. The methods to verify the teeth development stages showed a coincidence in results
Mestrado
Radiologia
Mestre em Odontologia
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44

Bayer, Ulku. "The Use Of Design Consultancy For Companies Producing Furniture On Contract Basis: The Case Of A Medium Sized Company In Turkey". Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607150/index.pdf.

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Contract furniture which is manufactured depending on the client&
#8217
s design or specification requirements on a contract basis is executed in small and medium sized furniture companies in Turkey. This one-of-a-kind production organization provides component manufacturing opportunity to furniture SMEs via subcontracting. In this study, the use of design consultancy is investigated to understand how it should be used in the current organization, in order to implement this production system efficiently. This study also examines contract furniture production to have foresight for the development of furniture SMEs in Turkey. In a literature review, the generic context of contracting activities in relation to design activity is investigated. Methods of design consultancy use in product development processes are searched. Design consultancy in construction industry is examined Data about design and production capabilities of Turkish furniture SMEs is collected. Production planning processes of a contract furniture company was investigated and discussed in a case study. These two groups of data were compared in order to drive conclusions.
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MARINI, CLAUDINE. "Les urgences psychiatriques au c. H. G. De roanne : etude retrospective ; a propos de 844 patients admis sur une periode de 6 mois". Lyon 1, 1994. http://www.theses.fr/1994LYO1M274.

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Луцюк, Ольга Володимирівна, e Olga Lucyuk. "Метод аналізу електроретиносигналу для підвищення інформативності систем діагностики стану сітківки ока людини". Master's thesis, Тернопільський національний технічний університет імені Івана Пулюя, кафедра біотехнічних систем, 2019. http://elartu.tntu.edu.ua/handle/lib/29630.

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Проект виконано на кафедрі біотехнічних систем Тернопільського національного технічного університету імені Івана Пулюя
У дипломній роботі розроблено методу аналізу електроретиносигналу для підвищення інформативності систем діагностики стану сітківки ока людини. В основі методу аналізу електроретиносигналу лежить процедура Вейвлет перетворення з базисною функцією Морле. За інформативні оцінки прийнято усередненні спектри коефіцієнтів вейвлет перетворення (усереднених вейвлет-спенктрів), які дають змогу дослідити характерні часові флуктації у структурі електроретиносигналу у різних масштабах часу, що є важливим при своєчасному прояву патологічних змін у функціонуванні сітківки ока. Розроблено алгоритм та програмне забезпечення аналізу електроретиносигналу із використанням програмного середовища Matlab.
In the diploma work the method of analysis of the electroretinosignal was developed to increase the informativeness of systems of diagnostics of the state of the retina human eye. The method analysis of the ectroretinosignal is based on the wavelet transform procedure with the basic Morle function. For informative estimation the averaged spectra of the wavelet transform coefficients (averaged wavelet spectra) were adopted, which make it possible to investigate the characteristic temporal fluctuations in the structure of the electroretinosignal at different scales of time which is important for the timely manifestation of pathological changes in the functioning of the retina. Algorithm and software for analysis of electroretinosignal with the use of software Matlab have been developed.
ЗМІСТ ПЕРЕЛІК УМОВНИХ ПОЗНАЧЕНЬ 8 ВСТУП 9 РОЗДІЛ 1. ОГЛЯД ВІДОМИХ МЕТОДІВ АНАЛІЗУ ЕЛЕКТРОРЕТИНОСИГНАЛУ 12 1.1 Електроретинографія та електроретиносигнал 12 1.2 Методи реєстрації електроретиносигналів 15 1.3 Методи аналізу електроретиносигналу в існуючих системах діагностики стану сітківки ока людини 22 1.3.1 Морфологічний аналіз 22 1.3.2 Статистичний аналіз 23 1.3.3 Спектральний аналіз 25 1.3.4 Синфазний аналіз 26 1.3.5 Компонентний аналіз 27 1.4 Висновки до розділу 1 28 РОЗДІЛ 2. МАТЕМАТИЧНА МОДЕЛЬ ЕЛЕКТРОРЕТИНОСИГНАЛУ 29 2.1 Математична модель електроретиносигналу 29 2.2 Верифікація обґрунтованої структури математичної моделі електроретиносигналу в програмному середовищі Matlab 33 2.3 Висновки до розділу 2 35 РОЗДІЛ 3. МЕТОД ТА АЛГОРИТМ АНАЛІЗУ ЕЛЕКТРОРЕТИНОСИГНАЛУ 36 3.1 Система для реєстрації електроретиносигналу 36 3.2 Вейвлет аналіз електроретиносигналу 38 3.3 Вибір базисної функції Вейвлет-аналізу електроретиносигналу 43 3.4 Алгоритм аналізу електроретиносигналу 46 3.5 Висновки до розділу 3 47 РОЗДІЛ 4. РЕЗУЛЬТАТИ АНАЛІЗУ ЕЛЕКТРОРЕТИНОСИГНАЛУ 49 4.1. Вибір програмного середовища розробки програмного забезпечення аналізу електроретиносигналу 49 4.2 Розробка програмного забезпечення Вейвлет-аналізу електроретиносигналу 50 4.3 Результати аналізу електроретиносигналу 54 4.4 Висновки до розділу 4 56 РОЗДІЛ 5. СПЕЦІАЛЬНА ЧАСТИНА 57 5.1 Метрологічне забезпечення медико-біологічних досліджень 57 5.2 Обґрунтування вибору УДК напряму наукового дослідження 60 5.3 Висновки до розділу 5 78 РОЗДІЛ 6. ОБГРУНТУВАННЯ ЕКОНОМІЧНОЇ ЕФЕКТИВНОСТІ 63 6.1 Науково-технічна актуальність науково-дослідної роботи 63 6.2 Розрахунок витрат на проведення науково-дослідної роботи 63 6.3 Науково-технічна ефективність науково-дослідної роботи 69 6.4 Висновки до розділу 6 73 РОЗДІЛ 7. ОХОРОНА ПРАЦІ ТА БЕЗПЕКА В НАДЗВИЧАЙНИХ СИТУАЦІЯХ 74 7.1 Охорона праці 74 7.2 Безпека в надзвичайних ситуаціях 75 7.3 Висновки до розділу 7 78 РОЗДІЛ 8. ЕКОЛОГІЯ 79 8.1 Актуальність проблеми охорони навколишнього середовища 79 8.2 Забруднення довкілля, що виникають при виготовленні системи реєстрації пульсового сигналу 80 8.3 Заходи зі зменшення забруднення довкілля 81 8.4 Висновки до розділу 8 84 ВИСНОВКИ 85 СПИСОК ВИКОРИСТАНИХ ДЖЕРЕЛ 86 ДОДАТКИ 92 Додаток А. Текст програмного забезпечення аналізу електроретиносигналу 93 Додаток Б. Копія тези конференції 95
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47

Raynor, Susan J. "A specification of Canon 843 [par.] 2 parents as other members of the Christian faithful who have a duty to prepare their children for the sacraments of initiation /". Online full text .pdf document, available to Fuller patrons only, 2003. http://www.tren.com.

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48

Branche, Fabienne. "Thrombolyse en phase pre hospitaliere : a propos de 42 cas traites par le samu 84". Aix-Marseille 2, 1992. http://www.theses.fr/1992AIX20169.

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Sousa, Luis Carlos Silva de. "A noção de excessus em Tomás de Aquino (STh. q. 84, a. 7 ad 3) sobre a crítica de Cornelio Fabro a Karl Rahner". Pontifícia Universidade Católica de São Paulo, 2011. https://tede2.pucsp.br/handle/handle/11575.

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Made available in DSpace on 2016-04-27T17:26:57Z (GMT). No. of bitstreams: 1 Luis Carlos Silva de Sousa.pdf: 17519641 bytes, checksum: 0950925e65bdebf21f9afbe5334bfa74 (MD5) Previous issue date: 2011-08-30
Faculdade Católica de Fortaleza
The aim of the thesis is to examine the notion of excessus in the Suma de Teologia (Ia, q. 84, a. 7 ad 3) by Thomas Aquinas, through Cornelius Fabro s critique of Karl Rahner. With the analysis of the notion of excessus we tackle the problem concerning the possibility knowing of God. The hypothesis we raised initially with Cornelio Fabro is that Rahner's interpretation of notion of excessus as anticipation (Vorgriff) does not preserve the transcendence of God. Karl Rahner's commitment to the anthropocentric change would distort the original meaning of excessus as an overtaking or transcendence, which comes from Dionysus, in the line of the "negative theology": the mediation of the transcendental subjectivity that would eventually immanentalize the esse of God in thought. It is not our intention to analyze, however, if Fabro s "principle of immanence" applies or not to Rahner, but only to certify that Rahner reinterprets Sto. Thomas. In fact, Fabro and Rahner part from different perspectives when they approach the text of Thomas Aquinas, the real "touchstone" of our investigation.We do not intend to examine whether Karl Rahner, in his own way (that is, with features including those that were not extracted from Thomas Aquinas text), in fact preserves the divine transcendence. From the historical point of view (which is ours), Fabro is right to stress that the notion of excessus in Thomas Aquinas comes from Dionysus, but it is wrong not to recognize the legitimate role that the negative judgement exerts on the nonquiddidative knowledge of God. We conclude with a critique of the critique of Fabro, because, in criticizing what he understands by pseudo-Thomism in Rahner, he eventually affects Thomas Aquinas himself
O objetivo da tese consiste em analisar a noção de excessus na Suma de Teologia (Ia, q. 84, a. 7 ad 3) de Tomás de Aquino, através da crítica de Cornélio Fabro a Karl Rahner. O problema de fundo se refere à possibilidade do conhecimento de Deus. Argumentamos que a noção de excessus como ultrapassamento ou transcendência em Tomás de Aquino provém de Dionísio, na linha da tradição da teologia negativa . A hipótese que levantamos, inicialmente com Cornelio Fabro, é a de que o repensamento da noção de excessus como antecipação (Vorgriff), tal como Rahner a interpreta, não preservaria a transcendência de Deus. O compromisso de Karl Rahner com a reviravolta antropocêntrica deturparia o sentido original de excessus como transcendência, porque a mediação da subjetividade transcendental acabaria por imanentizar o esse de Deus no pensar. Não é nossa intenção analisar, porém, se o princípio de imanência , proposto por Fabro, se aplica ou não a Rahner, mas apenas constatar que Rahner reinterpreta Sto. Tomás. Na verdade, Fabro e Rahner partem de perspectivas diferentes quando se aproximam do texto de Tomás de Aquino, a pedra de toque da nossa investigação. Não pretendemos examinar se Karl Rahner, a seu modo (isto é, com recursos inclusive não extraídos do texto de Tomás de Aquino), de fato preserva a transcendência divina. Do ponto de vista histórico (que é o nosso), Fabro tem razão em acentuar que a noção de excessus em Tomás de Aquino provém de Dionísio, mas está equivocado por não reconhecer o papel legítimo que o juízo negativo exerce no conhecimento não-quididativo de Deus. Concluímos com uma crítica à crítica de Fabro, porque, ao criticar o que ele entende por pseudo-tomismo em Rahner, acaba por atingir o próprio Tomás de Aquino
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50

LARBRE, ELISABETH. "Contribution a l'etude des cellulases excretees par trichoderma reesei : caracterisation du complexe cellulolytique de la souche cl 847 en vue de ses applications industrielles". Paris 7, 1990. http://www.theses.fr/1990PA077056.

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Le procede d'hydrolyse enzymatique de la biomasse lignocellulosique est etudie a l'i. F. P. En vue de son application a la production de carburants oxygenes. Les preparations d'enzymes cellulolytiques sont obtenues par fermentation aerobie du champignon trichoderma reesei. Ce travail de these a eu trois objectifs principaux: 1) le choix et la mise en place d'une methode de caracterisation du complexe cellulasique, par une technique a la fois simple et rapide. La methode retenue est la chromatofocalisation. Cette technique a permis en une seule operation, la resolution du mout cellulasique en une huitaine de pics bien distincts; 2) la mise en application de cette methode, d'une part, au suivi des fermentations productrices de cellulases, d'autre part, a l'etude des operations d'hydrolyse; 3) l'etude approfondie des cellobiohydrolases; ces enzymes representent a elles seules, les deux tiers des proteines totales du complexe cellulasique de t. Reesei. Ce travail a consiste pour partie, en une etude de leur mode d'action. Nous avons mis en evidence l'existence d'un phenomene de synergie, entre les endoglucanases et les exoglucanases, d'une part, mais aussi entre les exoglucanases elles-memes. Afin de mieux comprendre ces phenomenes, nous avons cherche a acquerir une meilleure connaissance des caracteristiques physicochimiques d'une enzyme a activite exoglucanase. Pour ce faire un etalon cellobiohydrolase 1 a ete elabore. Apres obtention de l'immunserum anti-c. B. H. 1, nous avons recherche a parfaire la purification de cette enzyme par la technique d'immuno-affinite. Le travail accompli ici, devrait permettre, a moyen terme, la mise au point d'un dosage specifique de l'enzyme, et eventuellement, une analyse des impuretes ou contaminants, et a plus long terme, le sequencage de la proteine et le clonage du gene responsable de sa synthese
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