Bibliografias temáticas / 871/.01

Literatura científica selecionada sobre o tema "871/.01"

Autor: Grafiati

Publicado: 26 de julho de 2024

Última modificação: 27 de julho de 2024

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Artigos de revistas sobre o assunto "871/.01"

Novak, Anne J., Deanna M. Grote, Steven C. Ziesmer, Michael P. Kline, Michelle K. Manske, Susan Slager, Thomas E. Witzig et al. "Elevated Serum B-Lymphocyte Stimulator Levels in Patients With Familial Lymphoproliferative Disorders". Journal of Clinical Oncology 24, n.º 6 (20 de fevereiro de 2006): 983–87. http://dx.doi.org/10.1200/jco.2005.02.7938.

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Purpose Serum B-lymphocyte stimulator (BLyS) levels have been found to be elevated in a number of immune disease models. Therefore, we sought to establish whether BLyS levels were elevated in patients with B-cell lymphoproliferative disorders and to determine whether elevated BLyS levels correlated with clinical characteristics of the disease. Patients and Methods Specimens were collected from the peripheral blood of individuals diagnosed with B-cell chronic lymphocytic leukemia (B-CLL; n = 70) or from age- and sex-matched patients seen at the same institution (n = 41). Serum BLyS levels were determined by enzyme-linked immunosorbent assay, and sequencing of the BLyS promoter was performed by conventional methods and confirmed by restriction fragment length polymorphism analysis. Results We found that elevated BLyS levels were more common in patients with familial B-CLL than individuals with sporadic B-CLL or normal controls. Because of this association, we sequenced the BLyS promoter in patients with B-CLL and normal controls and identified a polymorphic site, −871 C/T. We found that the wild-type sequence was significantly underrepresented in patients with familial B-CLL (4%) compared with patients with sporadic B-CLL (30%; P = .01) or controls (24%; P = .04). Furthermore, using a luciferase reporter under control of the BLyS promoter containing either a C or a T at position −871, we found that the reporter construct containing a T at −871 had a 2.6-fold increase in activity (P = .004). Conclusion Our data suggest serum BLyS levels are elevated in patients with familial B-CLL and that elevated BLyS levels correlate with the presence of a T at −871 in the BLyS promoter.

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Berczi, Csaba, János Dócs e Tibor Flaskó. "Nyílt és laparoszkópos műtéttel végzett radikális prostatectomiák után kialakult szövődmények összehasonlítása". Magyar Urológia 34, n.º 3 (2022): 97–101. http://dx.doi.org/10.22591/magyurol.2022.3.berczics.97.

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Célkitűzés: A vizsgálatban a prosztatatumorok miatt nyílt és laparoszkópos eljárással végzett radikális prostatectomiák utáni szövődmények gyakoriságát tanulmányozták intézetükben. Betegek és módszerek: A tanulmányban a 2015. 01. 01. és 2020. 01. 01. között prosztatadaganat miatt radikális prostatectomián átesett 871 beteg adatai kerültek feldolgozásra. Az 1. csoportba (n: 707) tartozó betegek esetében laparoszkópos, míg a 2. csoportba sorolt betegeknél (n:164) nyílt, retropubikus radikális prostatectomia történt. A betegek átlagos életkora 65,6±6,3 év, míg az átlagos PSA-szint az 13,1±13,0 ng/ml volt. A szövődmények osztályozása során a Clavien–Dindo-féle klasszifikációt használták. Eredmények: A korai posztoperatív szakban az 1. csoportban Clavien–Dindo-szerinti grade 1+2 szövődmény 91 esetben (12,8%) míg grade 3+4 szövődmény 19 betegben (2,6%) alakult ki. A 2. csoportban Clavien–Dindo-szerinti grade 1+2 szövődmény 91 (55,4%), míg Grade 3+4 szövődmény 9 (5,4%) fordult elő. A grade 1+2 szövődmények előfordulása szignifikánsan, (p<0,0001), míg a grade 3+4 komplikációké nem szignifikánsan (p=0,138) bizonyult magasabbnak a nyílt műtétes betegcsoportban. A késői posztoperatív szakban az 1. csoportban Clavien–Dindo-szerinti grade 1+2 szövődmény 11 alkalommal (1,5%), míg grade 3+4 szövődmény 12 betegben (1,7%) alakult ki. A 2. csoportban Clavien–Dindo-szerinti grade 1+2 szövődmény 5 esetben (3,0%), míg grade 3+4 szövődmény 7 alkalommal (4,2%) fordult elő. A késői komplikációk vonatkozásában sem a grade 1+2, sem a grade 3+4 szövődmények tekintetében nem volt szignifikáns különbség az 1. és a 2. csoport között (p=0,346 és p=0,122). Következtetések: Az eredmények alapján megállapítható, hogy a posztoperatív szövődmények lényegesen gyakrabban fordultak elő a nyílt műtéten átesett betegekben. Szignifikáns eltérést azonban csak a korai komplikációk esetében, az enyhébb (grade 1+2) formákban tapasztaltak a két csoport között.

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Martell Muñoz, Juan, Cirilo Humberto García Cadena, Leopoldo Daniel-González, Patricia Sánchez Miranda e Abraham Mendoza Martínez. "Estructura factorial de la escala de satisfacción con la vida y validez convergente con la escala de calidad de vida en preparatorianos mexicanos". Revista de Psicología y Ciencias del Comportamiento de la Unidad Académica de Ciencias Jurídicas y Sociales 9, n.º 2 (7 de dezembro de 2018): 30–45. http://dx.doi.org/10.29059/rpcc.20181207-70.

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El propósito de este estudio fue calcular tanto la validez de constructo como la validez convergente de la escala de Satisfacción con la Vida (SWL), de Diener, Emmons, Larsen y Griffin (1985), en 428 estudiantes de bachillerato. Se usaron análisis factorial exploratorio y confirmatorio. Diener et al. (1985) diseñan una escala que estandariza la medida de la satisfacción con la vida, de manera válida y confiable. Se encuentra que las ?´s de los ítems tienen un recorrido desde .58 hasta .88. El coeficiente de consistencia interna alfa de Cronbach es de .85, con un intervalo de confianza del 95% (de .826 a .871). El coeficiente de correlación de Pearson entre la SWLS y la escala de Calidad de Vida es de r= .395; p< .01; IC95%: .293, .486. Hay coincidencia entre los hallazgos arrojados por ambos tipos de análisis factorial. El modelo de medición se corresponde con el creado por Diener et al. (1985): los cinco ítems muestran validez y confiabilidad, al igual que lo reportado por otros estudios en diferentes contextos culturales.

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Inaba, Hidefumi, Yosuke Kaido, Saya Ito, Tomonao Hirobata, Gen Inoue, Takakazu Sugita, Yuki Yamamoto et al. "Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors". Endocrinology and Metabolism 37, n.º 1 (28 de fevereiro de 2022): 84–95. http://dx.doi.org/10.3803/enm.2021.1282.

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Background: Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM) is a rare critical entity. However, the etiology of ICI-T1DM remains unclear.Methods: In order to elucidate risk factors for ICI-T1DM, we evaluated the clinical course and immunological status of patients with ICI-T1DM who had been diagnosed during 2016 to 2021.Results: Seven of 871 (0.8%, six men and one woman) patients developed ICI-T1DM. We revealed that the allele frequencies of human leukocyte antigen (HLA)-DPA1*02:02 and DPB1*05:01 were significantly higher in the patients with ICI-T1DM In comparison to the controls who received ICI (11/14 vs. 10/26, P=0.022; 11/14 vs. 7/26, P=0.0027, respectively). HLA-DRB1*04:05, which has been found to be a T1DM susceptibility allele in Asians, was also observed as a high-risk allele for ICI-T1DM. The significance of the HLA-DPB1*05:01 and DRB1*04:05 alleles was confirmed by an analysis of four additional patients. The absolute/relative neutrophil count, neutrophils-lymphocyte ratio, and neutrophil-eosinophil ratio increased, and the absolute lymphocyte count and absolute/relative eosinophil count decreased at the onset as compared with 6 weeks before. In two patients, alterations in cytokines and chemokines were found at the onset.Conclusion: Novel high-risk HLA alleles and haplotypes were identified in ICI-T1DM, and peripheral blood factors may be utilized as biomarkers.

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Burns, Con, John J. Murphy e Ciaran MacDonncha. "Year in School and Physical Activity Stage of Change as Discriminators of Variation in the Physical Activity Correlate Profile of Adolescent Females". Journal of Physical Activity and Health 11, n.º 4 (maio de 2014): 721–28. http://dx.doi.org/10.1123/jpah.2011-0353.

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Background:Knowledge of the physical activity correlate profile of adolescent females will provide insight into decreasing physical activity patterns among adolescent females.Methods:Correlates of physical activity and physical activity stage of change were assessed during 2007–2008 among 871 Irish adolescent females in years 1–6 in secondary schools (15.28 ± 1.8 years). Multivariate Analysis of Variance was used to identify whether differences in correlates of physical activity could be detected across year in school and physical activity stages of change.Results:Significant differences (P < .01) were found in 11 of the 16 measured correlates across year in school and in 14 of the 16 correlates across stage of change. Effect size estimates and regression analysis revealed perceived competence, peer social support and intention to be physically active (partial eta range (ηp2) .21–.25) to be the most important predictors of physical activity stage of change.Conclusions:Females in more senior years in school and in earlier physical activity stages of change reported a significantly less positive physical activity correlate profile than females in junior years and in later physical activity stages of change. This finding supports the construct validity of the physical activity stages of change.

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Aguirre, Miguel Castresana, Annelie Johansson, Linda S. Lindström e Nick Tobin. "Abstract P6-01-08: Gene signatures provide independent prognostic information in elderly breast cancer patients". Cancer Research 83, n.º 5_Supplement (1 de março de 2023): P6–01–08—P6–01–08. http://dx.doi.org/10.1158/1538-7445.sabcs22-p6-01-08.

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Abstract Background: Elderly breast cancer patients (≥70 years old) are under-represented in clinical trials and remain an undertreated population. Gene expression signatures have been shown to add additional prognostic information beyond that of routine clinicopathological factors, however their utility in elderly breast cancer patients remains unclear. As such, the main aim of this study is to determine if gene signatures can provide prognostic information that may help to aid treatment decisions for elderly breast cancer patients. Material and methods: Research versions of the genomic grade index (GGI), 70-gene, 21-gene recurrence score (RS), cell cycle score (CCS), PAM50 and PAM50 Risk of Relapse score - Proliferation (ROR-P) signatures were applied to 39 open access breast cancer datasets totalling 9583 patients. After filtering based on age ≥ 70 years old, the presence of Estrogen Receptor (ER) and survival information availability 871 patients remained. The prognostic capacity of signatures was tested in all (N=871), Estrogen Receptor positive/Lymph node positive (ER+/LN+, N=335) and Estrogen Receptor positive/Lymph node negative (ER+/LN-, N=374) patients using Kaplan-Meier and multi-variable Cox proportional hazard modeling. Models were adjusted for tumor size, grade, ER and lymph node status in all patients, and tumor size and grade in the ER+/LN+ and ER+/LN- subgroup analyses. Recurrence Free Survival (RFS) censored at 10 years was used as clinical endpoint and defined as the time from date of curative surgery to the time of recurrence or death. Both loco-regional recurrences and distant metastatic events were included in this endpoint. Results: Tumours from patients ≥ 70 years of age showed high levels of ER (87%), were large (69% ≥ 20 mm) and were of intermediate or high grade (82%). All gene signatures were statistically significant in Kaplan-Meier analysis of all and ER+/LN+ patients (Logrank P < 0.001). This significance remained in multi-variable analysis (Cox proportional hazards, P ≤ 0.05) with the exception of PAM50 which showed a trend (P ≤ 0.1) in ER+/LN+ patients. In ER+/LN- patients the GGI, 70-gene, PAM50, ROR-P, and CCS signatures were significant in Kaplan-Meier analysis (Logrank P ≤ 0.05) but only the 70-gene, PAM50, ROR-P, and CCS signatures remained so in multi-variable analysis (Cox proportional hazards, P ≤ 0.05). Conclusions: In general, we found that gene signatures provide statistically significant prognostic information in Kaplan-Meier and multi-variable analyses of all, ER+/LN+ and ER+/LN- breast patients over the age of 70. Table 1: Multivariable proportional hazard (Cox) analyses for all gene signatures for patients above age of 70. NOTE: Bold values indicate P < 0.05. aAdjusted for tumor size, tumor grade, estrogen receptor status, and lymph node status. bAdjusted for tumor size and tumor grade. Citation Format: Miguel Castresana Aguirre, Annelie Johansson, Linda S. Lindström, Nick Tobin. Gene signatures provide independent prognostic information in elderly breast cancer patients [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P6-01-08.

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Stankovska, Gordana, Fadbi Osmani, Svetlana Pandilovska Grncarovska e Slagana Angelkoska. "Relationship Between Stressful Life Events And Anxiety During The Period Of Adolescence". European Scientific Journal, ESJ 12, n.º 11 (27 de abril de 2016): 332. http://dx.doi.org/10.19044/esj.2016.v12n11p332.

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The purpose of this study is to investigate the relationships between stressful life events and anxiety during the period of adolescence. It is known that stressful life events are commonly studied risk and environmental factors in the development of psychopathology in childhood and adolescence. In addition, physical and psychological symptoms of anxiety are often associated with stressful life events. These events are related to the different experiences of conflict and disrupted communication in the family. Subsequently, these events directly or indirectly affect the self-esteem and the self-image of adolescents during the period of adolescence. This research starts with the assumption that stressful life events predicted anxiety during the period of adolescence. Another assumption, in this research, is that females have higher level of anxiety compared with males. This study was conducted on a sample of 160 participants (80 girls and 80 boys) students in the fourth year of secondary school. The instruments used in the research include: scale of stressful life events for children and adolescents – Stress-D, and the Scale for anxiety for children and adolescents – SCAD-62. The results showed that stressful life events were significantly associated with anxiety symptoms (r= .962, p<.01). Also, the symptoms of anxiety are closely associated with medical (F,24,135= .871, p<.05) and family stressful events (F,24,135= 2.017, p<.05). There were significant relationship between medical stressful life events and gender (p= .045), and social stressful life events and gender (p= .001). On the other hand, there was a negative correlation between academic stressful life events and gender (p= .944), and family stressful life events and gender (p= .564). In conclusion, the results of the study show that females have higher level of anxiety compared with males (r= .985, p<.01). The results show that there is a significant relationship between specific types of stressful life events, including those related to physical health and family which discord the anxiety during the period of adolescence.

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Hogan, Christopher, Darci Bowles, Moshe Feldman, Shannon Lubin e Markos Kashiouris. "871". Critical Care Medicine 43 (dezembro de 2015): 219. http://dx.doi.org/10.1097/01.ccm.0000474699.75650.64.

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Meert, Kathleen, e Susan Eggly. "871". Critical Care Medicine 40 (dezembro de 2012): 1–328. http://dx.doi.org/10.1097/01.ccm.0000425086.74471.65.

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Goldstein, Jennifer, Kirk Gosik, Angela Heisey, Camille Filoromo e Scott Armen. "871". Critical Care Medicine 42 (dezembro de 2014): A1570. http://dx.doi.org/10.1097/01.ccm.0000458368.20726.0d.

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Teses / dissertações sobre o assunto "871/.01"

Veltz, Lionel Bienaymé Olivier Freeman Ken. "Formation du disque de la Voie Lactée". Strasbourg : Université Louis Pasteur, 2008. http://eprints-scd-ulp.u-strasbg.fr:8080/871/01/VELTZ_Lionel_2007.pdf.

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Cerroni, Simone. "Subjective Probabilities in Choice Experiments' Design: Three Essays". Doctoral thesis, University of Trento, 2013. http://eprints-phd.biblio.unitn.it/871/1/Dissertation_Cerroni.pdf.

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This dissertation which consists of three essays investigates the influence of subjective probabilities on decision making processes under conditions of risk. In particular, it examines whether subjects adjust new risk information on their prior subjective estimates, and, to what extent this adjustment affects their choices. In the first essay, by using an artefactual field experiment, I examine the potential correlation between incentive compatibility and validity of subjective probabilities elicited via the Exchangeability Method, an innovative elicitation mechanism which consists of several chained questions. Here, validity is investigated using de Finettiâs notion of coherence under which subjective probabilities are coherent if and only if they obey all axioms and theorems of probability theory. Experimental results suggest that subjects provided with monetary incentives and randomized questions more likely express valid subjective probabilities than others because they are not aware of the chaining which undermines the incentive compatibility of the Exchangeability Method. In the second essay, by using the same experimental data, I show that valid subjective probabilities do not significantly diverge from invalid ones, indicative of little effect of internal validity on the actual magnitude of subjective probabilities. In the third essay, by using a field Choice Experiment, I investigate to what extent subjects adjust risk information given in the status quo alternative on their subjective probability estimates. An innovative two-stage approach that incorporates subjective probabilities into Choice Experimentsâ design is developed to investigate this phenomenon, known as the scenario adjustment. In the first stage, subjective probabilities that given outcomes will occur are elicited using the Exchangeability Method. In the second stage, two treatment groups are designed: in the first group, each subject is presented with a status quo alternative which incorporates her/his subjective probabilities, and, hence, no adjustment is required; in the second group, each subject faces a status quo alternative where the presented risk is not consistent with her/his probability estimates, and, hence, a mental adjustment to the scenario might take place. By comparing willingness to pay across the treatment groups, my results suggest that, when subjects are provided with SQ alternatives in which the risk is lower than the perceived one, the mental adjustment takes place, but, when subjects are provided with SQ alternatives in which the risk is higher than their own estimates, these subjects appear to make irrational choices.

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Livros sobre o assunto "871/.01"

Ovid. Ars amatoria: Book 3. Cambridge, UK: Cambridge University Press, 2003.

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Nicholas, Horsfall, ed. A companion to the study of Virgil. Leiden: E.J. Brill, 1995.

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Virgil. Virgil's Eclogues. Philadelphia: University of Pennsylvania Press, 2010.

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Geraldine, Herbert-Brown, ed. Ovid's Fasti: Historical readings at its bimillennium. Oxford: Oxford University Press, 2002.

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Ovid. Sorrows of an exile. Oxford: Oxford University Press, 1995.

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Ovid. Culpa silenda: Le elegie dell'"error" ovidiano. Bari: Edipuglia, 2002.

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Ovid. Fasti. 2^a ed. Cambridge, Mass: Harvard University Press, 1989.

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Ovid. Fasti. London: Penguin Books, 2000.

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Ovid. Fasti. Cambridge, U.K: Cambridge University Press, 1998.

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Ovid. Publii Ovidii Nasonis Fastorum libri = Fastos. México, D.F: Universidad Nacional Autónoma de México, Imprenta Universitaria, 1985.

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Trabalhos de conferências sobre o assunto "871/.01"

Tripathy, Srinibas, Lucien Koopmans, Stina Hemdal e Claes Kuylenstierna. "A Numerical Investigation of Gas Exchange Modeling and Performance Prediction of a Camless Two-Stroke Hydrogen Engine". In WCX SAE World Congress Experience. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2023. http://dx.doi.org/10.4271/2023-01-0232.

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<div class="section abstract"><div class="htmlview paragraph">Heavy-duty vehicles are primarily powered by diesel fuel, emitting CO<sub>2</sub> emissions regardless of the exhaust after-treatment system. Contrastingly, a hydrogen engine has the potential to decarbonize the transportation sector as hydrogen is a carbon free, renewable fuel. In this study, a multi-physics 1D simulation tool (GT-Power) is used to model the gas exchange process and performance prediction of a two-stroke hydrogen engine. The aim is to establish a maximum torque-level for a four-stroke hydrogen engine and then utilize different methods for two-stroke modeling to achieve similar torque by optimizing the gas exchange process. A camless engine is used as base, enabling the flexibility to utilize approximately square valve lift profiles. The preliminary step is the GT-Power model validation, which has been done using diesel and hydrogen engines (single-cylinder heavy-duty) experiments at different operating points (871 rpm, 1200 rpm, 1259 rpm, and 1508 rpm). Thereafter, the validated model is used to simulate four-stroke hydrogen engine performance at different intake and exhaust pressures. The last step was to modify the model to operate in two-stroke mode. The intake and exhaust valve closing timings, pressure differential, and air-fuel equivalence ratio were varied to investigate the delivery ratio, charging efficiency, trapping efficiency, and scavenging efficiency for perfect displacement and perfect mixing modes. The variable valve-actuated camless two-stroke hydrogen engine achieved similar torque to that of a conventional cam-operated four-stroke hydrogen engine by optimizing valve timings, pressure differential, and in-cylinder air-fuel mixture proportions.</div></div>

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