Siga este link para ver outros tipos de publicações sobre o tema: 793.3/2.
Artigos de revistas sobre o tema "793.3/2"
Crie uma referência precisa em APA, MLA, Chicago, Harvard, e outros estilos
Veja os 19 melhores artigos de revistas para estudos sobre o assunto "793.3/2".
Ao lado de cada fonte na lista de referências, há um botão "Adicionar à bibliografia". Clique e geraremos automaticamente a citação bibliográfica do trabalho escolhido no estilo de citação de que você precisa: APA, MLA, Harvard, Chicago, Vancouver, etc.
Você também pode baixar o texto completo da publicação científica em formato .pdf e ler o resumo do trabalho online se estiver presente nos metadados.
Veja os artigos de revistas das mais diversas áreas científicas e compile uma bibliografia correta.
1
Naderi, Ruhollah, Farzad Bijani, Akbar Karami, Bhagirath S. Chauhan e Todd P. Egan. "Effects of summer savory (Satureja hortensis L.) and sweet corn (Zea mays L. saccharata) intercropping on crop production and essential oil profiles of summer savory". PeerJ 11 (30 de janeiro de 2023): e14753. http://dx.doi.org/10.7717/peerj.14753.
Texto completo da fonteResumo:
A 2-year field experiment evaluated the effects of sweet corn-summer savory intercropping on crop productivity and essential oil (EO) composition of summer savory. Five cropping patterns of Corn 100%:Savory 0%, C75:S25, C50:S50, C25:S75, and C0:S100 were tested. The highest corn yield (2,440 kg ha−1) was obtained in a corn monoculture, but was not significantly different from C75:S25 or C50:S50. However, in both years the highest savory yield was obtained in S100 (793.3 g m−2 and 816.6 g m−2, respectively). Savory yields decreased as the proportion of corn increased. The land equivalent ratios in C25:S75, C50:S50, and C75:S25 were 1.54 ± 0.07, 1.56 ± 0.03, and 1.35 ± 0.1, respectively. Monocropped savory had the highest EO value followed by C25:S75 and C50:C50. However, no significant differences were found among these three treatments. Gas chromatography-mass spectrometry (GC–MS) analysis showed that the major components were carvacrol (35.88%–42.96%), γ-terpinene (18.45%–20.03%), ρ-cymene (11.77%–12.24%), and α-terpinene (2.75%–3.96%). The highest amount of carvacrol was recorded in C25:S75 (42.96%). This study suggests that intercropping of corn and savory represents an effective sustainable strategy, especially for smallholders, as a way to increase their overall land productivity and to improve the quality of savory’s EO.
2
Bernat, Katarzyna, Magdalena Zielińska, Dorota Kulikowska, Agnieszka Cydzik-Kwiatkowska, Irena Wojnowska-Baryła, Beata Waszczyłko-Miłkowska e Beata Piotrowicz. "The effect of the excess sludge pretreatment on biogas productivity". Technical Sciences 1, n.º 22 (11 de fevereiro de 2019): 75–86. http://dx.doi.org/10.31648/ts.4349.
Texto completo da fonteResumo:
To intensify biogas production during anaerobic stabilization of organic matter in sludge, pretreatment is applied. The effect of pretreatment of excess activated sludge (AS) and excess aerobic granular sludge (GS) on biogas productivity (BP) and composition was investigated. The sludge was pretreated with homogenization (6,500 rpm for 0.5 min (H0.5) and 1 min (H1.0)) or ultrasound disintegration at 20 kHz (50% amplitude for 2 min (D50%_2.0) and 4 min (D50%_4.0), and 100% amplitude for 4 min (D100%_4.0)). BP of AS of GS without pretreatment was 603.3±5 dm3/kg TS (793.4±7 dm3/kg VS); that was 200.6±4 dm3/kg TS (480.8±6 dm3/kg VS). With disintegration, the BP of AS increased by 7.8% (650.4±10 dm3/kg TS) (D50%_2.0) and 16.1% (700.6±11 dm3/kg TS) (D100%_4.0), and that of GS increased by 7.0% (214.0±5 dm3/kg TS) (D50%_2.0) and 16.0% (232.8±5 dm3/kg TS) (D100%_4.0). With homogenization, BP increased by 2.0-3.0% (AS) and 1.6-3.2% (GS).
3
Sebastian, C. Peter, Sudhindra Rayaprol, Rolf-Dieter Hoffmann, Ute Ch Rodewald, Tania Pape e Rainer Pöttgen. "Structure and Properties of α- and β-CeCuSn: A Single Crystal and Mössbauer Spectroscopic Investigation". Zeitschrift für Naturforschung B 62, n.º 5 (1 de maio de 2007): 647–57. http://dx.doi.org/10.1515/znb-2007-0504.
Texto completo da fonteResumo:
Abstract Two modifications of CeCuSn were prepared from the elements: the high-temperature (β ) modification crystallizes directly from the quenched sample, while the low-temperature (α) modification is formed after annealing at 700 °C for one month. Both modifications were investigated by powder and single crystal X-ray diffraction. We find for β -CeCuSn the ZrBeSi-type structure, space group P63/mmc, a = 458.2(1), c = 793.7(2) pm, wR2 = 0.0727, 148 F2 values, 8 variable parameters. In the case of α-CeCuSn we find the NdPtSb-type structure, space group P63mc, a = 458.4(1), c = 785.8(2) pm, wR2 = 0.0764, 233 F2 values, 11 variable parameters. The copper and tin atoms build up layers of ordered [Cu3Sn3] hexagons. The layers are planar in β -CeCuSn, however, with highly anisotropic displacements of the copper and tin atoms. In α-CeCuSn a puckering effect is observed resulting in a decrease of the c lattice parameter. Both modifications of CeCuSn exhibit antiferromagnetic ordering, but there is a considerable difference in their magnetic behaviour. Anomalies in the physical properties of the α- and β -modifications of CeCuSn have been detected by Mössbauer spectroscopy and magnetic and specific heat measurements, which serve to explain the structure-property relations.
4
Mendes, Andreia, Ana Armada, Lília I. L. Cabral, Patrícia S. M. Amado, Lenea Campino, Maria L. S. Cristiano e Sofia Cortes. "1,2,4-Trioxolane and 1,2,4,5-Tetraoxane Endoperoxides against Old-World Leishmania Parasites: In Vitro Activity and Mode of Action". Pharmaceuticals 15, n.º 4 (3 de abril de 2022): 446. http://dx.doi.org/10.3390/ph15040446.
Texto completo da fonteResumo:
Leishmaniasis remains one of the ten Neglected Tropical Diseases with significant morbidity and mortality in humans. Current treatment of visceral leishmaniasis is difficult due to a lack of effective, non-toxic, and non-extensive medications. This study aimed to evaluate the selectivity of 12 synthetic endoperoxides (1,2,4-trioxolanes; 1,2,4,5-tetraoxanes) and uncover their biochemical effects on Leishmania parasites responsible for visceral leishmaniasis. The compounds were screened for in vitro activity against L. infantum and L. donovani and for cytotoxicity in two monocytic cell lines (J774A.1 and THP-1) using the methyl thiazol tetrazolium assay. Reactive oxygen species formation, apoptosis, and mitochondrial impairment were measured by flow cytometry. The compounds exhibited fair to moderate anti-proliferative activity against promastigotes of the 2 Leishmania species, with IC50 values ranging from 13.0 ± 1.7 µM to 793.0 ± 37.2 µM. Tetraoxanes LC132 and LC138 demonstrated good leishmanicidal activity on L. infantum amastigotes (IC50 13.2 ± 5.2 and 23.9 ± 2.7 µM) with low cytotoxicity in mammalian cells (SIs 22.1 and 118.6), indicating selectivity towards the parasite. Furthermore, LC138 was able to induce late apoptosis and dose-dependent oxidative stress without affecting mithocondria. Compounds LC132 and LC138 can be further explored as potential antileishmanial chemotypes.
5
Han, Z., Y. Shen, J. Diana Di Mavungu, D. Zhang, D. Nie, K. Jiang, S. De Saeger e Z. Zhao. "Relationship between environmental conditions, TRI5 gene expression and deoxynivalenol production in stored Lentinula edodes infected with Fusarium graminearum". World Mycotoxin Journal 11, n.º 2 (25 de abril de 2018): 177–86. http://dx.doi.org/10.3920/wmj2017.2245.
Texto completo da fonteResumo:
This study made the first attempt to relate the production of deoxynivalenol (DON) to the expression of TRI5 gene in Fusarium graminearum as a function of interacting environmental factors (water activity (aw) (0.95-0.98), temperature (20-30 °C) and incubation time (7 day-28 day)), so as to investigate its production mechanisms in Lentinula edodes. Changes in temperature, water activity and incubation time could significantly (P<0.01) affect DON production and TRI5 gene expression. The highest DON concentration (793.5±27.4 μg/kg) and TRI5 gene expression (2−ΔΔCt=38.8±4.8) were observed when the cultures were incubated at 20 °C and 0.98 aw for 21 days. Multi-regression analysis was performed and nonlinear models based on polynomial equations were established to uncover the individual effects of temperature, water activity and incubation time as well as their interactions on DON production and TRI5 gene expression. The established model was further used to develop contour maps to predict the DON production and TRI5 gene expression in relation to storage conditions in L. edodes. Highly significant positive correlation between DON production and fold TRI5 gene expression (R=0.5534, P<0.0001) was observed in this commodity. The production mechanisms of DON in L. edodes revealed in the present study will be beneficial for developing more effective targeted control strategies.
6
McIlvaine, Devon, Michael Stewart e Robert Anderson. "Noise Exposure Levels for Musicians During Rehearsal and Performance Times". Medical Problems of Performing Artists 27, n.º 1 (1 de março de 2012): 31–36. http://dx.doi.org/10.21091/mppa.2012.1006.
Texto completo da fonteResumo:
OBJECTIVES: The purpose of this study was to determine daily noise doses and 8-hour time weighted averages for rock band musicians, crew members, and spectators during a typical rehearsal and performance using both Occupational Safety and Health Administration (OSHA) and National Institute of Occupational Safety and Health (NIOSH) measurement criteria. DESIGN: Personal noise dosimetry was completed on five members of a rock band during one 2-hr rehearsal and one 4-hr performance. Time-weighted averages (TWA) and daily dose values were calculated using both OSHA and NIOSH criteria and compared to industry guidelines for enrollment in hearing conservation programs and the use of hearing protection devices. RESULTS: TWA values ranged from 84.3 to 90.4 dBA (OSHA) and from 90.0 to 96.4 dBA (NIOSH) during the rehearsal. The same values ranged from 91.0 to 99.7 dBA (OSHA) and 94.0 to 102.8 dBA (NIOSH) for the performance. During the rehearsal, daily noise doses ranged from 45.54% to 106.7% (OSHA) and from 317.74% to 1396.07% (NIOSH). During the performance, doses ranged from 114.66% to 382.49% (OSHA) and from 793.31% to 5970.15% (NIOSH). CONCLUSIONS: The musicians in this study were exposed to dangerously high levels of noise and should be enrolled in a hearing conservation programs. Hearing protection devices should be worn, especially during performances. The OSHA measurement criteria yielded values significantly more conservative than those produced by NIOSH criteria. Audiologists should counsel musician-patients about the hazards of excessive noise (music) exposure and how to protect their hearing.
7
Umezurike, G. M. "The effect of glycerol on the activity of β-glucosidase from Botryodiplodia theobromae Pat". Biochemical Journal 254, n.º 1 (15 de agosto de 1988): 73–76. http://dx.doi.org/10.1042/bj2540073.
Texto completo da fonteResumo:
1. In the activity of the high-Mr beta-glucosidase A (beta-D-glucoside glucohydrolase, EC 3.2.1.21) obtained from culture filtrates of Botryodiplodia theobromae Pat. on o-nitrophenyl beta-D-glucopyranoside as substrate, both Vmax. and Km increased non-linearly with increasing concentration of glycerol, and the Vmax./Km(app.) ratio decreased non-linearly with increasing concentration of glycerol. 2. No increase in rate was observed with phenyl beta-D-glucopyranoside as substrate in the presence of up to 250 mM-glycerol, indicating that glucosylation is rate-limiting with this substrate. 3. With o-nitrophenyl beta-D-glucopyranoside, p-nitrophenyl beta-D-glucopyranoside and phenyl beta-D-glucopyranoside as substrates, kappa cat. values of 793.7 s-1, 62.8 s-1 and 5.4 s-1 respectively were calculated. 4. With o-nitrophenyl beta-D-glucopyranoside and phenyl beta-D-glucopyranoside as substrate, alpha-deuterium kinetic isotope effects of 1.9 +/- 0.03 and 1.01 +/- 0.01 respectively were found; in the presence of 200 mM-glycerol the values were 1.21 +/- 0.03 and 1.02 +/- 0.01 respectively. 5. In the presence of a large excess of o-nitrophenyl beta-D-glucopyranoside [(S] = 35.7 Km), the amount of o-nitrophenol and also of the transglucosylation product formed by beta-glucosidase action increased non-linearly, whereas that of glucose formed decreased non-linearly with increasing glycerol concentration. 6. All these results were found to fit the data calculated from rate equations derived on the basis of the proposed mechanism of enzyme action involving two ion-pair intermediates and a covalent alpha-D-glucosyl-enzyme in the reaction sequence [Umezurike (1987) Biochem. J. 241, 455-462].
8
Novik, Y., S. Kunnakkat, B. Donahue, S. Rush, J. Golfinos, E. Parker e A. Narayana. "Role of HER2 status in the treatment of brain metastases arising from breast cancer by stereotactic radiosurgery." Journal of Clinical Oncology 29, n.º 27_suppl (20 de setembro de 2011): 117. http://dx.doi.org/10.1200/jco.2011.29.27_suppl.117.
Texto completo da fonteResumo:
117 Background: Overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer has been shown to be an independent risk factor of development of brain metastases (BM). However, the role of HER2 on the radiosensitivity of BM remains controversial. We investigated the efficacy of single fraction stereotactic radiosurgery (SRS) in the treatment of limited BM from breast cancer, based on the HER2 status. Methods: From 2004 to 2010, 57 patients with limited BM were treated with SRS using Leksell Gamma-Knife to a median dose of 20 Gy (range 12-20 Gy) prescribed to the 50% isodose line. The median number of lesions treated were 2 (range 1-7) and the median tumor volume was 92.8 mm3 (range 3.4 -793.7 mm3). There were 27 HER2 positive patients, with 32 ER positive and 22 PR positive patients. Six patients were triple negative. ER/PR information was not available for 4 patients. Overexpression of HER2 was defined as HER2 +++ by immunohistochemistry using the DAKO HercepTest or fluorescent in situ hybridization (FISH) analysis. Time to local recurrence, time to development of new brain metastases, progression-free survival (PFS), and overall survival (OS) were assessed from the date of SRS. Results: With a median follow-up of 11 months (range 1-66 months), 12 patients developed recurrence at the previously treated site (9 HER2 positive patients) and 30 developed new brain metastases (16 HER2 positive patients) The median PFS and OS for all patients were 8 and 16 months respectively. The median PFS for HER2 positive patients compared to HER2 negative patients were 7 and 11 months, respectively (p=0.352). HER2 positive patients had a median OS of 20 months, compared to 14 months in HER2 negative patients (p=0.086). Five patients went on to develop leptomeningeal disease, all of whom were HER2 positive. Conclusions: HER2 overexpression does not increase the risk of recurrence at the site of treatment or appearance of new BM. It does not affect PFS or OS following SRS. However, it remains a risk factor for the development of leptomeningeal disease.
9
Senge, Mathias O., Maria da Graça H. Vicente, Sean R. Parkin, Håkon Hope e Kevin M. Smith. "Structural Investigations on Mono- and Di-Acrolein Substituted Ni(II) Porphyrins and a Ni(II) Benzochlorin. Model Compounds for Photosensitizers in Photodynamic Therapy". Zeitschrift für Naturforschung B 47, n.º 8 (1 de agosto de 1992): 1189–202. http://dx.doi.org/10.1515/znb-1992-0822.
Texto completo da fonteResumo:
The structures of four Ni complexes and a free base related to tetrapentanoporphyrin (TC7P) and octaethylporphyrin (OEP) have been determined by X-ray crystallograpic methods. The Ni(II) complexes exhibit considerable S4-ruffling induced by coordination hole contraction due to the low spin Ni(II). The degree of conformational distortion is enhanced by one or two additional acrolein substituents at the meso positions. The steric strain imposed by interaction of the meso substituent with the neighboring β-pyrrole substituents leads to a significant displacement from the mean plane of the molecule of the meso carbon(s) involved. Increasing non-planarity of the macrocycles is correlated with shifts to longer wavelenghts in the absorption spectra. Ring closures of the acrolein group to afford benzochlorin type pigments results in further bathochromic shifts and a very non-planar molecular conformation. Long wavelength absorbing pigments such as benzochlorins are useful photosensitizers for photodynamic therapy and thus one criterion for a good photosensitizer might be its conformational distortion. Crystal data – 3. C40H46N4 · CH2Cl2, Mr = 667.7, triclinic, P1̄, a = 7.776(5)Å, b = 8.556(4)Â, c = 14.509(8)Å, α = 73.96(1)°, β = 82.04(2)°, γ = 82.58(2)°, V = 914.5(9)Å3, Ζ = 1, Dx = 1.212 Mg/m3, (ΜοΚα) λ = 0.71069Å, μ = 0.209 mm-1, F(000) = 356, 130 Κ, R = 0.082 for 2217 reflections with I > 1.5σ(Ι). Ni4. C44H40N4NiO · CH2Cl2, Mr = 770.4, triclinic, P1̄, a = 11.283(3)Å, b = 11.800(4)Å, c = 15.871(7)Å, α = 79.28(3)°, β = 88.95(2)°, γ = 62.41(1)°, V = 1838.8(11)Å3, Ζ = 2, Dx = 1.391 Mg/m3, (ΜοΚα), μ = 0.715 mm-1, F(000) = 804, 130 Κ, R = 0.072 for 5309 reflections with I > 2.0σ(Ι). Ni5. C46H28N4NiO2 • CH2CH2, Mr = 812.4, triclinic, P1̄, a = 8.959(4)Å, b = 14.420(7)A, c = 15.471(5)Å, α = 102.73(4)°, β = 101.83(4)°, γ = 92.01(5)°, V = 1901.3(14)Å3, Z = 2, Dx = 1.419 Mg/m3, (ΜοΚα), μ = 0.679 mm-1, F(000) = 836, 130 Κ, R = 0.059 for 4197 reflections with I > 1.75σ(Ι). Ni7. C43H45N4NiO2·CH2Cl2, Mr = 793.5, triclinic, P1̄, a = 8.948(3)Å, b = 13.855(3)Å, c = 15.451(3)Å, α = 82.43(2)°, β = 78.79(2)°, γ = 81.24(2)°, V = 1846.7(8)Å3, Z = 2, Dx = 1.427 Mg/m3, (CuKa) λ = 1.54178 Å, μ = 2.448 mm-1, F(000) = 834, 126 K, R = 0.09 for 4039 reflections with I > 2.0σ(Ι). Ni8. C42H48N4NiO, Mr = 683.6, monoclinic, Ρ21/n, a = 15.168(6)Å, b = 14.796(3)Å, c = 15.983(4)Å, β= 97.17(3)°, V = 3552(2)Å3, Z = 4, Dxx = 1.278 Mg/m3, (ΜοΚα), μ = 0.584 mm-1, F(000) = 1456, 130 Κ, R = 0.042 for 5904 reflections with I > 2.5 σ(I).
10
Straková, E., P. Suchý, V. Večerek e L. Máchal. "The variation in amino acid levels in the blood plasma of breeding roosters during sexual maturation*". Archives Animal Breeding 45, n.º 3 (10 de outubro de 2002): 279–85. http://dx.doi.org/10.5194/aab-45-279-2002.
Texto completo da fonteResumo:
Abstract. The paper provides an overview of results obtained in the study of variation in free amino acid levels in the blood plasma of breeding roosters (RIR 05 line) during sexual maturation (in the 10th, 15th, 20th and 25th weeks of age). The results prove that dynamic changes in free amino acid concentrations in blood plasma are connected with the sexual maturation of breeding roosters. During this period the concentrations of each particular free amino acid varied at a significance level of P ≤ 0.05 and P ≤ 0.01. Furthermore, in most cases the plasma concentrations of free amino acids in the 10th and 15th week were higher in comparison with those in the 20th and 25th week. Interestingly, the concentrations of individual free amino acids ranged over a wide interval (units, tens and hundreds of μmol/l). In this respect the free amino acids in plasma can be divided into three groups. The first group consisted of amino acids that occurred at low molar concentration (up to 100 μmol/l): cysteic acid, aspartic acid, α-aminoadipic acid, methionine, isoleucine, γ-aminobutyric acid, 3-methylhistidine, tryptophan and ornitine. The second group included amino acids occurring at medium to high molar concentration (100–300 μmol/l): taurine, glutamine, 1/2 cystine, valine, leucine, tyrosine, phenylalanine, histidine, lysine and arginine. Finally, the third group contained threonine, serine, glutamic acid, proline, glycine and alanine that were present at high molar concentrations (above 300 μmol/l). Analyses of plasma in the period from the 10th to 25th week detected dynamic changes in levels of individual free amino acids and showed that the total content of these amino acids gradually decreased to the following mean values: 5 685.00 μmol/l in the 10th week, 5 076.21 μmol/l in the 15th week, 4 384.78 μmol/l in the 20th week and 4 793.30 μmol/l in the 25th week.
11
Almas, Khalid, Esam Tashkandi, Philippe Aramouni, Elie Zebouni e Salam Dib. "Fracture Resistance and Failure Location of Zirconium and Metallic Implant Abutments". Journal of Contemporary Dental Practice 9, n.º 7 (2008): 41–48. http://dx.doi.org/10.5005/jcdp-9-7-41.
Texto completo da fonteResumo:
Abstract Aim The purpose of this study was to evaluate the fracture resistance and failure location of single-tooth, implant-supported, all-ceramic restorations on different implant abutments subjected to a maximum load. Methods and Materials Forty Certain 3i implants and 20 ITI Straumann implants were used in this study in combination with 20 UCLA abutments, 20 ZiReal abutments, and 20 synOcta Ceramic Blanks to form three groups according to abutment type. All 60 abutments were prepared with standard measurements: a 1.0 mm deep chamfer, 2.0 mm of incisal reduction, and a total height of 7 mm. Sixty IPS Empress 2 full ceramic crowns were fabricated and cemented on each abutment with a resin cement. Static loading was simulated under maximum loading and fracture locations were noted. Results The mean load to failure data and standard deviations for the three groups were as follows: Group 1 (792.7 N ± 122.5) and Group 3 (793.6 ± 162.3) showed no significant difference in fracture resistance while the values for specimens in Group 2 (604 N ± 191.1) had the lowest mean value and were significantly lower. In Group 1, 16 crowns and four abutment fractures were reported, while in Group 3, 17 crowns and three abutments fractured. Group 2 actually showed three types of fractures. Two specimen fractures were located at the implant level, six with fractures occuring within the Empress 2 all-ceramic crown, and the remaining 12 failures were located at the abutment level. Conclusion Within the limitations of this laboratory study, the following conclusions were drawn: The mean load-to-failure values for all three groups were well above the reported normal maximal incisal load range. The load to failure for both the zirconium oxide (ZrO2) abutments (ZiReal on 3i Certain implants and synOcta Ceramic Blanks on SLA ITI Straumann implants) had mean fracture loads of 792.7 N (+122.6) and 604.2 N (+191.2), respectively. The zirconium oxide (ZrO2) ZiReal and titanium (UCLA) abutments on the 3i Certain implants had statistically significantly higher fracture loads (792.7 N and 703.7 N, respectively) than those recorded for the 3i Ceramic Blank abutments on the SLA ITI Straumann implant (604.2 N). The ITI Straumann Ceramic Blank abutments showed uniform fracture behavior. Fracture mainly emanated from the cervical buccal aspect of the abutment. Clinical Significance The three abutments tested showed they can withstand clinical loads above the normal range of mastication. Citation Aramouni P, Zebouni E, Tashkandi E, Dib S, Salameh Z, Almas K. Fracture Resistance and Failure Location of Zirconium and Metallic Implant Abutments. J Contemp Dent Pract 2008 November; (9)7:041-048.
12
Wang, Ruixiang, Yanyang Wang, Zheqin Chen, XiaoCong Zhong, Yongmin Xie, Xiaobo Ji, Jiaming Liu, Shubiao Xia e Zhifeng Xu. "PVP-Assisted Iron-Doped ZIF-8 as an Efficient Fe-N-C Oxygen Reduction Electrocatalyst for Zinc-Air Batteries". Journal of The Electrochemical Society, 16 de junho de 2022. http://dx.doi.org/10.1149/1945-7111/ac797f.
Texto completo da fonteResumo:
Abstract Transition metal/nitrogen carbon composite (M/NC) is a highly active oxygen reduction reaction (ORR) electrocatalyst, widely used in fuel cells and zinc-air batteries. Herein, a uniform and regular PVP-assisted iron-doped nano dodecahedron (ZP0.1F/NC) is prepared by a simple and efficient one-step in-solution reaction, followed by controlled in-situ pyrolysis. The synthesized electrocatalyst showed excellent electrocatalytic ORR activity in an alkaline medium. Compared with standard 20% Pt/C electrocatalyst, ZP0.1F/NC exhibited onset potential (Eonset) (0.974 V vs. 0.967 V), half-wave potential (E1/2) (0.861 V vs. 0.857 V) and the limiting current density (jd) was 6.373 mA cm-2 vs. 5.401 mA cm-2, also better than the Fe doped ZIF-8 nitrogen composite (ZF/NC), PVP auxiliary ZIF-8 (ZP0.1/NC) and pure ZIF-8 nitrogen composite (Z/NC) synthesized by the same procedure. In addition, the zinc-air battery assembled with ZP0.1F/NC also exhibits outstanding discharge capacity, with a specific capacity and energy density of 793.3 mAh g-1 and 974.9 Wh kgZn-1, respectively, much higher than that of commercial 20% Pt/C-based zinc-air battery (719.8 mAh g-1, 842.6 Wh kgZn-1), indicating its great potential in practical energy conversion and storage.
13
Denison, Madeline, e Craig Nolan Streu. "Synthesis and Evaluation of a Photoswitchable COX‐2 Inhibitor". FASEB Journal 33, S1 (abril de 2019). http://dx.doi.org/10.1096/fasebj.2019.33.1_supplement.793.3.
Texto completo da fonte
14
Davis, Harrison, Pooneh Bagher, Kim Dora e Christopher Garland. "Endogenous Acetylcholine Detected by Changes in [Ca 2+ ] i Within Isolated Endothelial Cell Tubes". FASEB Journal 29, S1 (abril de 2015). http://dx.doi.org/10.1096/fasebj.29.1_supplement.793.3.
Texto completo da fonte
15
Lesny, Paul, Mark Anderson, Gavin Cloherty, Michael Stec, Anja Haase-Fielitz, Mathias Haarhaus, Carla Santos, Carlos Lucas, Fernando Macario e Michael Haase. "Immunogenicity of a first dose of mRNA- or vector-based SARS-CoV-2 vaccination in dialysis patients: a multicenter prospective observational pilot study". Journal of Nephrology, 29 de maio de 2021. http://dx.doi.org/10.1007/s40620-021-01076-0.
Texto completo da fonteResumo:
Abstract Background Dialysis patients are at risk for lower SARS-CoV-2-vaccine immunogenicity than the normal population. We assessed immunogenicity to a first mRNA- or vector-based SARS-CoV-2-vaccination dose in dialysis patients. Methods In a multicenter observational pilot study, 2 weeks after a first vaccination (BNT162b2/Pfizer-BioNTech [Comirnaty] or ChAdOx1 nCoV-19/Oxford-Astra-Zeneca [Vaxzevria]), hemodialysis patients (N = 23), peritoneal dialysis patients (N = 4) and healthy staff (N = 14) were tested for SARS-CoV-2-spike IgG/IgM, Nucleocapsid-protein-IgG-antibodies and plasma ACE2-receptor-binding-inhibition capacity. Hemodialysis patients who had had prior COVID-19 infection (N = 18) served as controls. Both response to first SARS-CoV-2 vaccination and IgG spike-positivity following prior COVID-19 infection were defined as SARS-CoV-2 spike IgG levels ≥ 50 AU/mL. Results Vaccination responder rates were 17.4% (4/23) in hemodialysis patients, 100% (4/4) in peritoneal dialysis patients and 57.1% (8/14) in staff (HD vs. PD: p = 0.004, HD vs. staff: p = 0.027). Among hemodialysis patients, type of vaccine (Comirnaty N = 11, Vaxzevria N = 12, 2 responders each) did not appear to influence antibody levels (IgG spike: Comirnaty median 0.0 [1.–3. quartile 0.0–3.8] versus Vaxzevria 4.3 [1.6–20.1] AU/mL, p = 0.079). Of responders to the first dose of SARS-CoV-2 vaccination among hemodialysis patients (N = 4/23), median IgG spike levels and ACE2-receptor-binding-inhibition capacity were lower than that of IgG spike-positive hemodialysis patients with prior COVID-19 infection (13/18, 72.2%): IgG spike: median 222.0, 1.–3. quartile 104.1–721.9 versus median 3794.6, 1.–3. quartile 793.4–9357.9 AU/mL, p = 0.015; ACE2-receptor-binding-inhibition capacity: median 11.5%, 1.–3. quartile 5.0–27.3 versus median 74.8%, 1.–3. quartile 44.9–98.1, p = 0.002. Conclusions Two weeks after their first mRNA- or vector-based SARS-CoV-2 vaccination, hemodialysis patients demonstrated lower antibody-related response than peritoneal dialysis patients and healthy staff or unvaccinated hemodialysis patients following prior COVID-19 infection. Graphic abstract
16
Schoettler, Michelle, Elizabeth O. Stenger, Kathleen Spencer, Deborah Lutterman, Savanah Rumbika, Jayre A. Jones, Ann E. Haight et al. "Sickle cell disease is a risk factor for transplant-associated thrombotic microangiopathy in children". Blood Advances, 8 de setembro de 2022. http://dx.doi.org/10.1182/bloodadvances.2022008058.
Texto completo da fonteResumo:
Transplant associated thrombotic microangiopathy (TA-TMA) and sickle cell disease (SCD) share features of endothelial and complement activation. Thus, we hypothesized that SCD is a risk factor for TA-TMA and that pre-hematopoietic cellular transplantation (HCT) markers of endothelial dysfunction and complement activation would be higher in SCD patients. Children who underwent haploidentical or matched sibling donor (MSD) first HCT between January 2015- June 2020 were included in this IRB approved, single institution, retrospective study. Of 115 children, 52 had SCD and 63 underwent HCT for non-SCD indications. There were no significant differences in severe grade III-IV acute graft versus host disease (GVHD) in SCD vs. non-SCD HCT recipients. The non-SCD cohort had significantly more CMV positive recipients, radiation containing preparative regiments, and PBSC graft sources (p=0<0.05); all described risk factors for developing TA-TMA. Despite this, 7/52 (13%) of SCD patients developed TA-TMA compared to 1/63 (2%) non-SCD patients (p=0.015). Risk was highest in those who underwent haploidentical HCT (OR 33, 95% CI 1.4 - 793.2). Adjusting for HLA match, GVHD, post HCT viral infection, stem cell source and myeloablation, SCD remained a risk for developing TA-TMA (OR 12.22, 95% CI 1.15- 129.6). In available pre-HCT samples, there were no differences in complement biomarkers in those with SCD and those without, though SCD patients did have significantly higher markers of endothelial activation, sVCAM-1 and p-selectin levels. In conclusion, children with SCD merit careful screening for TA-TMA post HCT, particularly those receiving a haploidentical HCT.
17
Gong, Jing, Hui Dong, Qing-Song Xia, Zhao-yi Huang, Ding-kun Wang, Yan Zhao, Wen-hua Liu et al. "Correlation analysis between disease severity and inflammation-related parameters in patients with COVID-19: a retrospective study". BMC Infectious Diseases 20, n.º 1 (dezembro de 2020). http://dx.doi.org/10.1186/s12879-020-05681-5.
Texto completo da fonteResumo:
Abstract Background COVID-19 is highly contagious, and the crude mortality rate could reach 49% in critical patients. Inflammation concerns on disease progression. This study analyzed blood inflammation indicators among mild, severe and critical patients, helping to identify severe or critical patients early. Methods In this cross-sectional study, 100 patients were included and divided into mild, severe or critical groups according to disease condition. Correlation of peripheral blood inflammation-related indicators with disease criticality was analyzed. Cut-off values for critically ill patients were speculated through the ROC curve. Results Significantly, disease severity was associated with age (R = -0.564, P < 0.001), interleukin-2 receptor (IL2R) (R = -0.534, P < 0.001), interleukin-6 (IL-6) (R = -0.535, P < 0.001), interleukin-8 (IL-8) (R = -0.308, P < 0.001), interleukin-10 (IL-10) (R = -0.422, P < 0.001), tumor necrosis factor α (TNFα) (R = -0.322, P < 0.001), C-reactive protein (CRP) (R = -0.604, P < 0.001), ferroprotein (R = -0.508, P < 0.001), procalcitonin (R = -0.650, P < 0.001), white cell counts (WBC) (R = -0.54, P < 0.001), lymphocyte counts (LC) (R = 0.56, P < 0.001), neutrophil count (NC) (R = -0.585, P < 0.001) and eosinophil counts (EC) (R = 0.299, P < 0.001). With IL2R > 793.5 U/mL or CRP > 30.7 ng/mL, the progress of COVID-19 to critical stage should be closely observed and possibly prevented. Conclusions Inflammation is closely related to severity of COVID-19, and IL-6 and TNFα might be promising therapeutic targets.
18
Paul, Frank, Sabine Baumann, Brian Anderson e Philipp Rastner. "Deriving a year 2000 glacier inventory for New Zealand from the existing 2016 inventory". Annals of Glaciology, 20 de abril de 2023, 1–11. http://dx.doi.org/10.1017/aog.2023.20.
Texto completo da fonteResumo:
Abstract Due to adverse snow and cloud conditions, only a few inventories are available for the maritime glaciers in New Zealand. These are difficult to compare as different approaches and baseline data have been used to create them. In consequence, glacier fluctuations in New Zealand over the past two decades are only known for a few glaciers based on field observations. Here we present the results of a new inventory for the ‘year 2000’ (some scenes are from 2001 and 2002) that is based on glacier outlines from a recently published inventory for the year 2016 and allowed consistent change assessment for nearly 3000 glaciers over this period. The year 2000 inventory was created by manual on-screen digitizing using Landsat ETM+ satellite imagery (15 m panchromatic band) in the background and the year 2016 outlines as a starting point. Major challenges faced were late and early seasonal snow, clouds and shadow, the geo-location mismatch between Landsat and Sentinel-2 as well as the correct interpretation of ice patches and ice under debris cover. In total, we re-mapped 2967 glaciers covering an area of 885.5 km2 in 2000, which is 91.7 km2 (or 10.4%) more than the 793.8 km2 mapped in 2016. Area change rates (mean rate −0.65% a−1) increase towards smaller glaciers. Strongest area loss from 2000 to 2016 occurred at elevations ~1900 m but the highest relative loss was found below 800 m a.s.l. In total, 109 glaciers split into two or more entities and 264 had wasted away by 2016.
19
Feng, Zhe, Xiantong Cao, Changying Zhao, Jialan Niu, Yang Yan, Tao Shi, Junjun Hao e Xinglong Zheng. "Serum CIRP increases the risk of acute kidney injury after cardiac surgery". Frontiers in Medicine 10 (3 de janeiro de 2024). http://dx.doi.org/10.3389/fmed.2023.1258622.
Texto completo da fonteResumo:
IntroductionAcute kidney injury (AKI) is a frequent perioperative complication. The underlying mechanisms of cardiac surgery-associated AKI are still not completely elucidated. Cold-induced RNA-binding protein (CIRP) has been subsequently found to be regulated by various stress conditions. During cardiac surgery and cardiopulmonary bypass (CPB), the host is subjected to hypothermia and inadequate organ perfusion, resulting in an upregulation of CIRP secretion. The aim of this study is to evaluate the role of elevated extracellular CIRP level as a contributing factor in the development of AKI.MethodsA total of 292 patients who underwent cardiac surgery were retrospectively enrolled and their serum samples were collected preoperative and postoperative. Demographic data, intraoperative data, in-hospital outcomes, and the occurrence of AKI were also collected for the patients. The correlation between CIRP and intraoperative procedures, as well as its association with postoperative outcomes were analyzed.ResultsIn multivariable analysis, higher ΔCIRP (p = 0.036) and body mass index (p = 0.015) were independent risk factors for postoperative AKI. Meanwhile, patients with postoperative AKI exhibited lower survival rate in 2-year follow-up (p = 0.008). Compared to off-pump coronary artery bypass grafting surgery, patients who underwent on-pump coronary artery bypass grafting, valve surgery, aortic dissection and other surgery showed higher ΔCIRP, measuring 1,093, 666, 914 and 258 pg/mL, respectively (p < 0.001). The levels of ΔCIRP were significantly higher in patients who underwent CPB compared to those who did not (793.0 ± 648.7 vs. 149.5 ± 289.1 pg/mL, p < 0.001). Correlation analysis revealed a positive correlation between ΔCIRP levels and the duration of CPB (r = 0.502, p < 0.001). Patients with higher CIRP levels are at greater risk of postoperative AKI (OR: 1.67, p = 0.032), especially the stage 2–3 AKI (OR: 2.11, p = 0.037).ConclusionCIRP secretion increases with prolonged CPB time after cardiac surgery, and CIRP secretion is positively correlated with the duration of CPB. Cardiac surgeries with CPB exhibited significantly higher levels of CIRP compared to non-CPB surgeries. Elevation of CIRP level is an independent risk factor for the incidence of AKI, especially the severe AKI, and were associated with adverse in-hospital outcomes.