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Artigos de revistas sobre o assunto "2001 g-491"
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Piestrzeniewicz, C., A. Sadowski, R. Dziuban, S. Odziemkowski e D. Wrona. "Results of ten-year rootstock testing with apple cultivar Rubin on fertile soil". Horticultural Science 40, No. 1 (19 de fevereiro de 2013): 31–36. http://dx.doi.org/10.17221/223/2012-hortsci.
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The experiment was carried out on a fertile alluvial soil at Warsaw-Wilanów, Central Poland, in years 2001–2010. Nineteen very dwarfing and dwarfing rootstocks were tested for vigorous apple cultivar Rubin. Ten-year-old trees were the largest on M 9 EMLA and P 62, smaller on Arm 18, and then on B 491, Unima and B 146. Even smaller were the trees on M 27, P 63 and P 64, and the smallest those on PJ 629. The highest cumulative yield (2002–2010) per tree was on P 66, Arm 18, M 9 EMLA, B 491 and P 16, lower on P 64, P 22, P 59, M 27, PB-4 and J-TE-G, and the lowest on PJ 629. Trees on P 59, PJ 629, PB-4, No. 280, J-TE-G, P 63, P 66, P 22, No. 387 and P 64 showed higher yield efficiency than those on M 9 EMLA or P 62. The mean fruit mass from trees on P 63, M 27, No. 387, Arm 18, P 62, P 64, No. 280, B 491, P 16, Unima and M 9 EMLA was larger than from trees on PJ 629. Trees on P 63, B 491, P 16, P 66, and P 65 produced higher cumulative yield per ha than trees on PB-4, J-TE-G or PJ 629.
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Mogensen, Mette M., John B. Tucker, John B. Mackie, Alan R. Prescott e Inke S. Näthke. "The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells". Journal of Cell Biology 157, n.º 6 (10 de junho de 2002): 1041–48. http://dx.doi.org/10.1083/jcb.200203001.
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Loss of full-length adenomatous polyposis coli (APC) protein correlates with the development of colon cancers in familial and sporadic cases. In addition to its role in regulating β-catenin levels in the Wnt signaling pathway, the APC protein is implicated in regulating cytoskeletal organization. APC stabilizes microtubules in vivo and in vitro, and this may play a role in cell migration (Näthke, I.S., C.L. Adams, P. Polakis, J.H. Sellin, and W.J. Nelson. 1996. J. Cell Biol. 134:165–179; Mimori-Kiyosue, Y., N. Shiina, and S. Tsukita. 2000. J. Cell Biol. 148:505–517; Zumbrunn, J., K. Inoshita, A.A. Hyman, and I.S. Näthke. 2001. Curr. Biol. 11:44–49) and in the attachment of microtubules to kinetochores during mitosis (Fodde, R., J. Kuipers, C. Rosenberg, R. Smits, M. Kielman, C. Gaspar, J.H. van Es, C. Breukel, J. Wiegant, R.H. Giles, and H. Clevers. 2001. Nat. Cell Biol. 3:433–438; Kaplan, K.B., A. Burds, J.R. Swedlow, S.S. Bekir, P.K. Sorger, and I.S. Näthke. 2001. Nat. Cell Biol. 3:429–432). The localization of endogenous APC protein is complex: actin- and microtubule-dependent pools of APC have been identified in cultured cells (Näthke et al., 1996; Mimori-Kiyosue et al., 2000; Reinacher-Schick, A., and B.M. Gumbiner. 2001. J. Cell Biol. 152:491–502; Rosin-Arbesfeld, R., G. Ihrke, and M. Bienz. 2001. EMBO J. 20:5929–5939). However, the localization of APC in tissues has not been identified at high resolution. Here, we show that in fully polarized epithelial cells from the inner ear, endogenous APC protein associates with the plus ends of microtubules located at the basal plasma membrane. Consistent with a role for APC in supporting the cytoskeletal organization of epithelial cells in vivo, the number of microtubules is significantly reduced in apico-basal arrays of microtubule bundles isolated from mice heterozygous for APC.
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Elias-Jones, A. C. "400 MCQs in Paediatrics for MRCPCH Part I.: By Nagi G Barakat. (Pp 212; pound14.95.) Royal Society of Medicine Press, 2001. ISBN 1-85315-491-1." Postgraduate Medical Journal 78, n.º 916 (1 de fevereiro de 2002): 125c—125. http://dx.doi.org/10.1136/pmj.78.916.125-c.
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Tosquy-Valle, Óscar H., Valentín A. Esqueda-Esquivel, Andrés Vásquez-Hernández, Ana Bertha Vargas-García e Isaac Meneses-Márquez. "COMPORTAMIENTO DE COMPONENTES TECNOLÓGICOS EN ARROZ DE TEMPORAL EN EL ESTADO DE VERACRUZ". Revista Fitotecnia Mexicana 28, n.º 1 (20 de março de 2005): 77. http://dx.doi.org/10.35196/rfm.2005.1.77.
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En Veracruz, México, se siembra la variedad de arroz (Oryza sativa L.) Milagro Filipino en temporal, cuya demanda está restringida en la entidad. En su cultivo se utilizan grandes cantidades de propanil, lo cual ha ocasionado el desarrollo de zacates con resistencia a este herbicida; también se emplean grandes cantidades de fertilizantesquímicos que favorecen el desarrollo de maleza y la incidencia de fitopatógenos. Para mejorar la tecnología de producción, durante el temporal 2001 se estableció un experimento en dos localidades del centro del estado de Veracruz. Se utilizó el diseño de bloques al azar con cuatro repeticiones y arreglo de tratamientos en parcelas subdivididas. Las parcelas grandes correspondieron a los genotipos Milagro Filipino y la línea II6911; las medianas a las mezclas de los herbicidas: pendimetalina + propanil (1600 + 2160 g i. a. ha-1) (testigo regional), clomazone + bispiribac-sodio (480 + 22 g i. a. ha-1) y clomazone + propanil (600 + 1440 g i. a. ha-1); y las parcelas chicas a los tratamientos de fertilización: 92N-46P-00K (testigo regional), biofertilizantes (Azospirillum brasilense + Glomus intraradix) inoculados a la semilla en dosis de 0.720 + 2.0 kg ha-1), 92N-46P-00K + biofertilizantes y 46N-23P-00K + biofertilizantes. Los resultados indicaron que II6911 y Milagro Filipino tuvieron un comportamiento similar en rendimiento de grano. El mejor control de maleza se obtuvo con clomazone + propanil y pendimetalina + propanil y con la primera se redujo en 33 % la dosis de propanil. No hubo respuesta significativa en componentes y rendimiento a la aplicación única de biofertilizantes. Los mayores rendimientos de grano se obtuvieron con 92N-46P00K + A. brasilense + G. intraradix y la fórmula 92N-46P-00K, pero la mejor relación beneficio/costo (1.59) y la mayor tasa de retorno (491 %), se obtuvieron con el primero de estos tratamientos.
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Nairat, Mazen. "Axial Angular Momentum of Bessel Light". Photonics Letters of Poland 10, n.º 1 (31 de março de 2018): 23. http://dx.doi.org/10.4302/plp.v10i1.787.
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Both linear and angular momentum densities of Bessel, Gaussian-Bessel, and Hankel-Bessel lasers are determined. Angular momentum of the three Bessel beams is illustrated at linear and circular polarization. Axial Angular momentum is resolved in particular interpretation: the harmonic order of the physical light momentum. Full Text: PDF ReferencesG. Molina-Terriza, J. Torres, and L. Torner, "Twisted photons", Nature Physics 3, 305 - 310 (2007). CrossRef J Arlt, V Garces-Chavez, W Sibbett, and K Dholakia "Optical micromanipulation using a Bessel light beam", Opt. Commun., 197, 4-6, (2001). CrossRef L. Ambrosio and H. Hernández-Figueroa, "Gradient forces on double-negative particles in optical tweezers using Bessel beams in the ray optics regime", Opt Exp, 18, 23 (2010). CrossRef I. Litvin, A. Dudley and A. Forbes, "Poynting vector and orbital angular momentum density of superpositions of Bessel beams", Opt Exp, 19, 18 (2011). CrossRef K Volke-Sepulveda, V Garcés-Chávez, S Chávez-Cerda, J Arlt and K Dholakia "Orbital angular momentum of a high-order Bessel light beam" , JOP B 4 (2). 2002. CrossRef M. Verma, S. Pal, S. Joshi, P. Senthilkumaran, J. Joseph, and H Kandpal, "Singularities in cylindrical vector beams", Jou. of Mod. Opt., 62 (13), 2015. CrossRef R. Borghi, M. Santarsiero, and M. Porras, "Nonparaxial Bessel?Gauss beams", J. Opt. Soc. Am. A, 18 (7) (2011). CrossRef L. Allen, M. Beijersbergen, R. Spreeuw, and J. Woerdman, "Orbital angular momentum of light and the transformation of Laguerre-Gaussian Laser modes", Phys Rev A, 45 (11): 8185-8189 (1992). CrossRef D. Mcglion and K. Dholakia, "Bessel beams: diffraction in a new light", Cont. Phys, 46(1) 15 ? 28. (2005). CrossRef F. Gori, G. Guattari and C. Padovani," Bessel-Gauss Beams", Opt. Commun., 64, 491, (1987). CrossRef V. Kotlyar, A. Kovalev, and A. Soifer, "Hankel?Bessel laser beams" J. Opt. Soc. Am. A, 29 (5) (2012). CrossRef L. Allen and M. Babiker "Spin-orbit coupling in free-space Laguerre-Gaussian light beams", Phys. Rev. A 53, R2937. CrossRef
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Stuteville, D. L. "First Report of Uromyces striatus on White Sweetclover in Kansas". Plant Disease 86, n.º 12 (dezembro de 2002): 1404. http://dx.doi.org/10.1094/pdis.2002.86.12.1404a.
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Rust was observed on leaves and stems of Melilotus alba Medik. plants in Riley County, Kansas, in November 1999. Rust reoccurred during the summers of 2000 and 2001. Uredinia were orange to reddish brown and predominately hypophyllous. Infected leaves wilted and abscised prematurely. Urediniospores were one-celled, globoid or broadly ellipsoid, and measured 20 to 25 × 18 to 22 μm. Walls were 1.0 to 1.2 μm thick, echinulate, and with three to five (mostly four) pores. Pores were equatorial, or nearly so, in approximately one half of the spores examined and scattered in the other half. Telia occurred in the fall, were sparse, amphigenous, exposed, and much darker than uredinia. Teliospores were single-celled, ovoid, subglobose or ellipsoidal, and measured 18 to 25 × 15 to 21 μm. Wall thickness was 1.3 to 2 μm. Walls had ridges approximately 1 μm wide, 2 μm apart, and arranged in a longitudinal pattern as shown in photographs of Uromyces striatus (2). Pedicels were hyaline, fragile, and short. Pathogenicity tests were conducted in growth chambers (4) with monouredinial isolate K-SC-R1 from M. alba. Pots containing plants of 80 USDA Plant Introduction (PI) core accessions representing 18 Melilotus spp. were evaluated. Total accessions tested per species were: 22 M. alba, 2 M. altissimus, 3 M. dentata, 2 M. elegans, 1 M. hirsutus, 4 M. indica, 2 M. infestus, 2 M. italica, 25 M. officinalis, 2 M. polonicus, 2 M. segetalis, 2 M. siculus, 2 M. speciosus, 2 M. spicatus, 1 M. suaveolens,2 M. sulcatus, 2 M. tauricus, and 2 M. wolgicus. Various amounts of rust developed on plants of 79 accessions; no plants of M. indica PI 234674 exhibited signs of rust. A host range study of an isolate of U. striatus from alfalfa (4) included these 18 Melilotus species; 10 were hosts. Therefore, the reactions of Medicago accessions to isolate K-SC-R1 were evaluated. These included nine alfalfa germ plasm sources representing the diversity in North American alfalfas and the cvs. Saranac and Moapa 69, which are commonly used susceptible controls in alfalfa rust evaluations. No rust resulted on any entry of Medicago sativa subsp. sativa. A few scattered, small, open uredinia occurred on plants of Medicago sativa subsp. falcata (‘WISFAL’ PI 560533). Of 11 Medicago lupulina PI accessions inoculated, rust resulted only on a few plants of PI 269926. All M. alba plants included as susceptible controls in all tests became heavily rusted. The causal fungus fits U. striatus Schroet. as described by uredinologists who disregard urediniospore pore position in this species. For example, illustrations of U. striatus urediniospores by Savulescu (3) show scattered pores, however, descriptions of U. striatus Schroet. in North America (1,2) specify equatorial pores. To my knowledge, this is the first report of scattered pores in U. striatus urediniospores in the United States. However, an examination of urediniospores from heavily rusted alfalfa plants collected in 2001 near Manhattan, KS and from isolate KR1 (4) also revealed urediniospores with variously distributed pores. U. striatus was reported on M. alba in Florida in 2001. References: (1) G. B Cummins. Rust Fungi on Legumes and Composites in North America. University of Arizona Press, Tucson, 1978. (2) J. A. Parmelee. Can. J. Bot. 40:491, 1962. (3) T. Savulescu. Monografia Uredinalelor din Republica Populara Romana. II. Acad. Repub. Pop. Rom. 1953. (4) D. Z. Skinner and D. L. Stuteville. Plant Dis. 79:456, 1995.
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Marlina. "MULTIDRUG RESISTANCE (MDR) OF V. Parahaemolyticus". Jurnal Riset Kimia 2, n.º 2 (12 de fevereiro de 2015): 112. http://dx.doi.org/10.25077/jrk.v2i2.150.
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Vol. 2, No. 2 ABSTRACT A total of 97 V. parahaemolyticus isolate from Padang were examined for their resistance to 15 antibiotics. V. parahaemolyticus isolated behaved as resistant to sulfamethoxazole (100%), rifampin (95%) and tetracycline (75%) and sensitive to norfloxacin (96%). Ampicillin still sensitive for V. parahaemolyticus isolated from human stools. All of isolates were sensitive to namely chloramphenicol and floroquinolones (ciprofloxacin and norfloxacin agents). RAPD-PCR profiling with three primers (OPAR3, OPAR4 and OPAR8) produced four major clusters (R1, R2, R3 and R4), 7 minor clusters (I, II, III, IV, V, VI and VII) and three single isolates. Keywords: V. parahaemolyticus, MDR, RAPD 1. D. Ottaviani, I. Bacchiocchi, L. Masini, F. Leoni, A. Carraturo, M. Giammarioli, and G. Sbaraglia, Antimicrobial susceptibility of potentially halophilic vibrios isolated from seafood, International Journal of Antimicrobial Agents 18: 135-140, (2001).2. A. Cespedes, and E. Larson, Knowledge, attitude and practices regarding antibiotic use among Latinos in the United States: Review and Recommendations, American Journal of Infection Control 34: 495-502, (2006).3. M. Lesmana, D. Subekti, C.H. Simanjuntak, P. Tjaniadi, J. R. Campbell, and B. A. Ofoyo, Vibrio parahaemolyticus associated with cholera-like diarrhea among patients in North Jakarta, Indonesia, Diagnostic Microbiology and Infectious Disease, 39: 71-75, (2001).4. S. Lu, B. Liu, B. Zhou, And R. E. Levin, Incidence and Enumeration of Vibrio parahaemolyticus in Shellfish from two retail Sources and the Genetic Diversity of isolates as Determined by RAPD-PCR Analysis, Food Biotechnology, 20: 193-209, (2006).5. M. Nishibuchi, Vibrio parahaemolyticus. In International handbook of foodborne pathogens, ed. M.D. Milliots and J. W. Bier, United States: Marcel Dekker, Inc. P, 2004, 237-252.6. L. Poirel, M. R. Martinez, H. Mammeri, A. Liard, and P. Nordmann, Origin of Plasmid-Mediated Quinolone Resistance Determinant QnrA, Antimicrobial Agents and Chemotherapy, 49: 3523-3525, (2005).7. S. Radu, N. Elhadi, Z. Hassan, G. Rusul, S. Lihan, N. Fifadara, Yuherman and E. Purwati, Characterization of Vibrio vulnificus isolated from cockles (Anadara granosa): antimicrobial resistance, plasmid profiles and random amplification of polymorphic DNA analysis, FEMS Microbiology Letters, 165: 139–143, (1998).8. S. Radu, N. Ahmad, F. H. Ling, and A. Reezal, Prevalence and resistance to antibiotics for Aeromonas species from retail fish in Malaysia, International of Journal Food Microbiology, 81: 261–266, (2003).9. B. Sarkar, N. R. Chowdhury, G. B. Nair, M. Nishibuchi, S. Yamasaki, Y. Takeda, S. K. Gupta, S. K. Bhattacharya, and Ramamurthy, Molecular characterization of Vibrio parahaemolyticus of similar serovars isolated from sewage and clinical cases of diarrhea in Calcutta, India, World Journal of Microbiology and Biotechnology, 19: 771-776, (2003). 10. S. Schwarz, and E. Chaslus-Dancla, Use of antimicrobials in veterinary medicine and mechanisms of resistance, Veterinary Residue, 32: 201–225, (2001).11. H. Sörum, and T.M. L’Abèe-Lund,. Antibiotic resistance in food-related bacteria – a result of interfering with the global web of bacterial genetics, International Journal of Food Microbiology, 78: 43–56, (2002).12. P. Tjaniadi, M. Lesmana, D. Subekti, N. Machpud, S. Komalarini, W. Santoso, C. H. Simanjuntak, N. Punjabi, J. R. Campbell, W. K. Alexander, H. J. Beecham, A. L. Corwin, and B. A. Oyofo, Antimicrobial Resistance of Bacterial Pathogens Associated with Diarrheal Patients in Indonesia, American Journal of Tropical Medicine and Hygiene, 68: 666-670, (2003).13. X. Zhao, and D. Drlica, Restricting the Selection of Antibiotic-Resistant Mutants: A General Strategy Derived from Fluoroquinolone Studies, Clinical Infectious Diseases, 33: S147-S156, (2001).
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Witt, Colleen M., e Ellen A. Robey. "The Ins and Outs of CCR7 in the Thymus". Journal of Experimental Medicine 200, n.º 4 (16 de agosto de 2004): 405–9. http://dx.doi.org/10.1084/jem.20041110.
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Although it is widely supposed that chemokines play a role in the thymus, most existing evidence is circumstantial. In this issue, two groups provide direct evidence that the chemokine receptor CCR7 is required for normal thymocyte migration (Ueno, T., F. Saito, D. Gray, S. Kuse, K. Hieshima, H. Nakano, T. Kakiuchi, M. Lipp, R. Boyd, and Y. Takahama. 2004. J. Exp. Med. 200:493–505; Misslitz, A., O. Pabst, G. Hintzen, L. Ohl, E. Kremmer, H. T. Petrie, and R. Forster. 2004. J. Exp. Med. 200:481–491). The two papers focus on distinct and opposite migration events, an early outward migration and a later inward migration. Together these papers provide a fascinating picture of the complex role of CCR7 in orchestrating thymocyte migration.
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Malmqvist, Björn, V. Benno Meyer-Rochow e Hans Silfverberg. "Reviews: Biological Atlas of Aquatic Insects, Insect Movement - mechanisms and consequences, Iconografía del género Iberodorcadion". Entomologica Fennica 14, n.º 1 (1 de janeiro de 2003): 60–64. http://dx.doi.org/10.33338/ef.84172.
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Wichard, W., Ahrens, W. & Eisenbeis, G. 2002: Biological Atlas of Aquatic Insects. — Apollo Books, Stenstrup (Denmark). 338 pp. 490 DKK.
Woiwood, I. P., Reynolds, D. R. & Thomas, C. D. 2001: Insect Movement: mechanisms and consequences. CABI-Publishing, Wallingford, Oxon (U.K.) and New York (U.S.A.). 458 pp.
Romero Samper, J. 2002: Iconografía del género Iberodorcadion. — Argania editio (Barcelona),192 pp. Price 105 Euros.
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Alsina, Ángel. "Itinerario de Enseñanza para el álgebra temprana". Revista Chilena de Educación Matemática 12, n.º 1 (20 de abril de 2020): 5–20. http://dx.doi.org/10.46219/rechiem.v12i1.16.
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En este artículo se presenta el Enfoque de los Itinerarios de Enseñanza de las Matemáticas, un enfoque que trata de ser respetuoso con las necesidades reales de los estudiantes para aprender matemáticas. En la primera parte se presenta la fundamentación del enfoque, que se sustenta en tres pilares interrelacionados: la perspectiva sociocultural del aprendizaje humano, el modelo de formación realista-reflexivo y la educación matemática realista; en la segunda parte se describe el enfoque, que se refiere a una secuencia de enseñanza intencionada que contempla tres niveles: 1) enseñanza en contextos informales (el entorno inmediato, los materiales manipulativos y los juegos); 2) enseñanza en contextos intermedios (recursos literarios y tecnológicos), y 3) enseñanza en contextos formales (recursos gráficos); finalmente, en la tercera parte se ejemplifica dicho enfoque con un itinerario de enseñanza del álgebra temprana para estudiantes de 3 a 12 años. Se concluye que la implementación de este enfoque requiere un amplio dominio de conocimientos didáctico-disciplinares, lo que implica un esfuerzo importante por parte de todos los agentes implicados en la formación del profesorado para que así, todo aquel profesional preocupado por mejorar su práctica docente y adaptarla a las exigencias del siglo XXI, pueda tener acceso a estos conocimientos. Referencias Alsina, Á. (2004). Barrinem? Matemàtiques amb jocs i problemes. Lògica 3. Cataluña: Edicions l'Àlber, S.L. Alsina, Á. (2010). La “pirámide de la educación matemática”, una herramienta para ayudar a desarrollar la competencia matemática. Aula de Innovación Educativa, 189, 12-16. Recuperado desde https://dugi-doc.udg.edu//bitstream/handle/10256/9481/PiramideEducacion.pdf Alsina, Á. (2018). Seis lecciones de educación matemática en tiempos de cambio: itinerarios didácticos para aprender más y mejor. Padres y Maestros, 376, 13-20. Alsina, Á. (2019a). La educación matemática infantil en España: ¿qué falta por hacer? Números. Revista de Didáctica de las Matemáticas, 100, 85-108. Recuperado desde http://www.sinewton.org/numeros/numeros/80/Volumen_80.pdf Alsina, Á. (2019b). Hacia una formación transformadora de futuros maestros de matemáticas: avances de investigación desde el modelo realista-reflexivo. Uni-pluriversidad, 19(2), 60-79. https://doi.org/10.17533/udea.unipluri.19.2.05 Alsina, Á. (2019c). Itinerarios didácticos para la enseñanza de las matemáticas (6-12 años). Barcelona: Editorial Graó. Alsina, Á. (2019d). Del razonamiento lógico-matemático al álgebra temprana en Educación Infantil. Edma 0-6: Educación Matemática en la Infancia, 8(1), 1-19. Recuperado desde https://www.edma0-6.es/index.php/edma0-6/article/view/70 Alsina, Á., y Domingo, M. (2010). Idoneidad didáctica de un protocolo sociocultural de enseñanza y aprendizaje de las matemáticas. Revista Latinoamericana de Investigación en Matemática Educativa, 13(1), 7-32. Recuperado desde http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-24362010000100002&lng=es&tlng=es. Alsina, Á., Novo, M. L., y Moreno, A. (2016). Redescubriendo el entorno con ojos matemáticos: Aprendizaje realista de la geometría en Educación Infantil. Edma 0-6: Educación Matemática en la Infancia, 5(1), 1-20. Recuperado desde http://funes.uniandes.edu.co/8423/ Australian Curriculum, Assessment and Reporting Authority. (2015). The Australian Curriculum: Mathematics. Recuperado desde http://v7-5.australiancurriculum.edu.au/Curriculum/Overview Azcarate, P., y Serradó, A. (2006). Tendencias didácticas en los libros de texto de matemáticas para la ESO. Revista de Educación, 340, 341-378. http://hdl.handle.net/11162/68967 Cardet, N. (2009). Els cigrons i la matemàtica. Suplement Guixdos, 156, 1-15. De Corte, E., Greer, B., y Verschaffel, L. (1996): Mathematics Teaching and Learning. En D. Berliner, y C. Calfee (Eds.), Handbook of Educational Psychology (pp. 491-549). Nueva York: Simon & Schuster Macmillan. Esteve, O., y Alsina, Á. (2010). Hacia el desarrollo de la competencia profesional del profesorado. En O. Esteve, K. Melief, y Á. Alsina (Eds.), Creando mi profesión. Una propuesta para el desarrollo profesional del profesorado (pp. 7-18). Barcelona: Editorial Octaedro. Fauzan, A., Plomp, T., y Slettenhaar, D. (2002). Traditional mathematics education vs. realistic mathematics education: Hoping for Changes. En Proceedings of the 3rd International Mathematics Education and Society Conference (pp. 1‐4). Copenhagen: Centre for Research in Learning Mathematics. Freudenthal, H. (1991). Revisiting mathematics education. Dordrectht: Kluwer Academic Publishers. Gómez, B. (2001). La justificación de la regla de los signos en los libros de texto: ¿por qué menos por menos es más? En P. Gómez, y L. Rico (Eds.), Iniciación a la investigación en didáctica de la matemática. Homenaje al profesor Mauricio Castro (pp. 257-275). Granada: Editorial Universidad de Granada. Hargreaves, A., Earl, L., Moore, S., y Manning, S. (2001). Aprender a cambiar. La enseñanza más allá de las materias y los niveles. Barcelona: Editorial Octaedro. Heuvel‐Panhuizen, M. (2002). Realistic mathematics education as work in progress. En F. L. Lin (Ed.), Common sense in mathematics education. Proceedings of 2001 The Netherlands and Taiwan Conference on Mathematics Education (pp. 1‐43). Taiwan: National Taiwan Normal University. Ivic, I. (1994). Lev Semionovick Vygotsky (1896-1934). Perspectivas: Revista Internacional de Educación Comparada, 34 (3-4), 773-799. Recuperado desde http://www.ibe.unesco.org/es/recursos/perspectivas-revista-trimestral-de-educaci%C3%B3n-comparada Korthagen, F. A. (2001). Linking practice and theory. The pedagogy of realistic teacher education. Londres: Lawrence Erlbaum Associates. Lerman, S. (2000). The social turn in mathematics education research. En J. Boaler (Ed.), Multiple perspectives on mathematics teaching and learning (pp. 19-44), Westport, CT: Ablex. Lerman, S. (2001). The function of discourse in teaching and learning mathematics: a research perspective. Educational Studies in Mathematics, 46(1-3), 87-113. https://doi.org/10.1007/0-306-48085-9_3 Llinares, S. (2008). Agendas de investigación en Educación Matemática en España. Una aproximación desde “ISI-web of knowledge” y ERIH. En R. Luengo, B. Gómez, M. Camacho, y L. J. Blanco (Eds.), Investigación en Educación Matemática XII (pp. 25-54). Badajoz: SEIEM. Melief, K., Tigchelaar, A., y Korthagen, K. (2010). Aprender de la práctica. En O. Esteve, K. Melief, y Á. Alsina (Eds.), Creando mi profesión. Una propuesta para el desarrollo profesional del profesorado (pp. 19-38). Barcelona: Octaedro. National Council of Teachers of Mathematics. (2000). Principles and Standards for School Mathematics. Reston, VA: Autor. National Council of Teachers of Mathematics. (2006). Curriculum Focal Points for Prekindergarten through Grade 8 Mathematics: a quest for coherence. Reston, V.A.: Autor. Ministry of Education of New Zealand (2017). Te Whāriki: Early Childhood Curriculum. Wellington: Autor. Ministry of Education of Singapore. (2013). Nurturing Early Learners: A Curriculum for Kindergartens in Singapore: Numeracy: Volume 6. Singapore: Autor. Olmos, G., y Alsina, Á. (2010). El uso de cuadernos de actividades para aprender matemáticas en educación infantil. Aula de Infantil, 53, 38-41. Schmittau, J. (2004). Vygostkian theory and mathematics education: Resolving the conceptual-procedural dichotomy. European Journal of Psychology of Education, 29(1), 19-43. Stacey, K., y Chick, H. (2004). Solving the problem with algebra. En K. Stacey, H. Chick, y M. Kendal (Eds.), The Future of Teaching and Learning of Algebra. The 12th ICMI Study (pp. 1-20). Boston: Kluwer. Tigchelaar, A., Melief, K., Van Rijswijk, M., y Korthagen, K. (2010). Elementos de una posible estructura del aprendizaje realista en la formación inicial y permanente del profesorado. En O. Esteve, K. Melief, y Á. Alsina (Eds.), Creando mi profesión. Una propuesta para el desarrollo profesional del profesorado (pp. 39-64). Barcelona: Octaedro. Torra, M. (2012). Patrones matemáticos en los cuentos. Cuadernos de Pedagogía, 421, 56-58. Recuperado desde http://www.cuadernosdepedagogia.com/content/Inicio.aspx Treffers, A. (1987). Three Dimensions. A Model of Goal and Theory Description in Mathematics Instruction - The Wiskobas Project. Dordrecht: Reidel Publishing Company. Vásquez, C., y Alsina, Á. (2015). Un modelo para el análisis de objetos matemáticos en libros de texto chilenos: situaciones problemáticas, lenguaje y conceptos sobre probabilidad. Profesorado, Revista de currículum y formación del profesorado, 19(2), 441-462. Recuperado desde https://dialnet.unirioja.es/servlet/articulo?codigo=5294556 Vásquez, C., y Alsina, Á. (2017). Proposiciones, procedimientos y argumentos sobre probabilidad en libros de texto chilenos de educación primaria. Profesorado, Revista de currículum y formación del profesorado, 21(1), 433-457. Recuperado desde https://www.redalyc.org/pdf/567/56750681022.pdf Vygotsky, L. S. (1978). Mind in society. The development of higher psychological processes. Cambridge, MA: Harvard University Press. Wertsch, J. V. (1985). Vygotsky y la formación social de la mente. Barcelona: Paidós. Wertsch, J. V. (1991). Voces de la mente. Un enfoque sociocultural para el estudio de la acción mediada. Madrid: Aprendizaje Visor. Financiamiento: FEDER/Ministerio de Ciencia, Innovación y Universidades de España. Agencia Estatal de Investigación Proyecto EDU2017-84979-R
Livros sobre o assunto "2001 g-491"
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Borisov, A. N. Kommentariĭ k bi︠u︡dzhetnomu kodeksu Rossiĭskoĭ Federat︠s︡ii ot 31 ii︠u︡li︠a︡ 1998 g. no. 145-FZ: Postateĭnyĭ : v red. federalʹnykh zakonov ot 5 avgusta 2000 g. no. 116-FZ,ot 8 avgusta 2001 g. no. 126-FZ, ot 29 mai︠a︡ 2002 g. no. 57-FZ, ot 10ii︠u︡li︠a︡ 2002 g. no. 86-FZ, ot 24 ii︠u︡li︠a︡2002 g. no. 104-FZ,ot 24 ii︠u︡li︠a︡ 2002 g. no. 110-FZ, ot 7 ii︠u︡li︠a︡ 2003 no.117-FZ, ot 7 ii︠u︡li︠a︡ 2003 g. no. 123-FZ, ot 11 noi︠a︡bri︠a︡2003 g. no. 147-FZ, ot 11 noi︠a︡bri︠a︡ 2003 g. no. 148-FZ, ot 8dekabri︠a︡ 2003 g. no. 158-FZ, ot 23 dekabri︠a︡ 2003 g. no. 184-FZ, ot 23 dekabri︠a︡ 2003 g. no. 186-FZ, ot 20 avgusta 2004 g. no.111-FZ, ot 20 avgusta 2004 g. no.120-FZ,ot 23 dekabri︠a︡ 2004 g. no. 174-FZ, ot 28 dekabri︠a︡ 2004 g. no. 182-FZ, ot 29 dekabri︠a︡ 2004 g. no. 195-FZ, ot 9 mai︠a︡ 2005 g. no.49-FZ, ot 1 ii︠u︡li︠a︡ 2005 g. no. 78-FZ, ot 12 okti︠a︡bri︠a︡2005 g. no. 127-FZ, ot 19 dekabri︠a︡ 2005 g. no. 159-FZ, ot 2 dekabri︠a︡ 2005 g. no. 176-FZ, ot 27 dekabri︠a︡ 2005 g. no. 197-FZ, ot 27 dekabri︠a︡ 2005 g. no.198-FZ, ot 3 i︠a︡nvari︠a︡ 2006 g. no. 6-FZ, ot 2 fevrali︠a︡ 2006 g. no. 19-FZ, ot 16 okti︠a︡bri︠a︡ 2006 g. no. 160-FZ, ot 3noi︠a︡bri︠a︡ 2006 g. no. 175-FZ, ot 4 dekabri︠a︡ 2006 g. no. 201-FZ, ot19 dekabri︠a︡ 2006 g. no. 237-FZ, ot 30 dekabri︠a︡ 2006 g. no. 265-FZ, ot 20apreli︠a︡ 2007 g. no. 53-FZ, ot 26 apreli︠a︡ 2007 g. no. 63-FZ, ot 24ii︠u︡li︠a︡ 2007 g. no. 212-FZ, ot 2 noi︠a︡bri︠a︡ 2007 g. no. 247-FZ i ot 8 noi︠a︡bri︠a︡ 2007 g. no. 257-FZ. Moskva: I︠U︡stit︠s︡inform, 2008.
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Borisov, A. N. Kommentariĭ k bi︠u︡dzhetnomu kodeksu Rossiĭskoĭ Federat︠s︡ii ot 31 ii︠u︡li︠a︡ 1998 g. no. 145-FZ: Postateĭnyĭ : v red. federalʹnykh zakonov ot 5 avgusta 2000 g. no. 116-FZ,ot 8 avgusta 2001 g. no. 126-FZ, ot 29 mai︠a︡ 2002 g. no. 57-FZ, ot 10ii︠u︡li︠a︡ 2002 g. no. 86-FZ, ot 24 ii︠u︡li︠a︡2002 g. no. 104-FZ,ot 24 ii︠u︡li︠a︡ 2002 g. no. 110-FZ, ot 7 ii︠u︡li︠a︡ 2003 no.117-FZ, ot 7 ii︠u︡li︠a︡ 2003 g. no. 123-FZ, ot 11 noi︠a︡bri︠a︡2003 g. no. 147-FZ, ot 11 noi︠a︡bri︠a︡ 2003 g. no. 148-FZ, ot 8dekabri︠a︡ 2003 g. no. 158-FZ, ot 23 dekabri︠a︡ 2003 g. no. 184-FZ, ot 23 dekabri︠a︡ 2003 g. no. 186-FZ, ot 20 avgusta 2004 g. no.111-FZ, ot 20 avgusta 2004 g. no.120-FZ,ot 23 dekabri︠a︡ 2004 g. no. 174-FZ, ot 28 dekabri︠a︡ 2004 g. no. 182-FZ, ot 29 dekabri︠a︡ 2004 g. no. 195-FZ, ot 9 mai︠a︡ 2005 g. no.49-FZ, ot 1 ii︠u︡li︠a︡ 2005 g. no. 78-FZ, ot 12 okti︠a︡bri︠a︡2005 g. no. 127-FZ, ot 19 dekabri︠a︡ 2005 g. no. 159-FZ, ot 2 dekabri︠a︡ 2005 g. no. 176-FZ, ot 27 dekabri︠a︡ 2005 g. no. 197-FZ, ot 27 dekabri︠a︡ 2005 g. no.198-FZ, ot 3 i︠a︡nvari︠a︡ 2006 g. no. 6-FZ, ot 2 fevrali︠a︡ 2006 g. no. 19-FZ, ot 16 okti︠a︡bri︠a︡ 2006 g. no. 160-FZ, ot 3noi︠a︡bri︠a︡ 2006 g. no. 175-FZ, ot 4 dekabri︠a︡ 2006 g. no. 201-FZ, ot19 dekabri︠a︡ 2006 g. no. 237-FZ, ot 30 dekabri︠a︡ 2006 g. no. 265-FZ, ot 20apreli︠a︡ 2007 g. no. 53-FZ, ot 26 apreli︠a︡ 2007 g. no. 63-FZ, ot 24ii︠u︡li︠a︡ 2007 g. no. 212-FZ, ot 2 noi︠a︡bri︠a︡ 2007 g. no. 247-FZ i ot 8 noi︠a︡bri︠a︡ 2007 g. no. 257-FZ. Moskva: I︠U︡stit︠s︡inform, 2008.
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Russia) Vserossiĭskoĭ nauchno-prakticheskoĭ konferent︠s︡ii khimiko-pedagogov smezhdunarodnym uchastiem (49th 2002 Saint Petersburg. Aktualʹnye problemy modernizat︠s︡ii khimiko-pedagogicheskogo i khimicheskogo obrazovanii︠a︡: Materialy 49 Vserossiĭskoĭ nauchno-prakticheskoĭ konferent︠s︡ii khimiko-pedagogov smezhdunarodnym uchastiem, 15-17 mai︠a︡ 2002 g., Sankt-Peterburg. Sankt-Peterburg: Rossiĭskiĭ gos. pedagogicheskiĭ universitet, 2002.
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United States. Congress. Senate. Committee on Energy and Natural Resources. Subcommittee on National Parks. Buffalo soldiers, protection of paleontological resources, Hibben Center, boundaries at Gunnison, Kris Eggle Center, Lewis and Clark Center, and Carter G. Woodson Home: Hearing before the Subcommittee on National Parks of the Committee on Energy and Natural Resources, United States Senate, One Hundred Eighth Congress, first session, on S. 499, S. 546, S. 643, S. 677, S. 1060, H.R. 255, H.R. 1012, H.R. 1577, June 10, 2003. Washington: U.S. G.P.O., 2003.
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Melanie Klein: Her Work in Context. Bloomsbury Publishing Plc, 2002.
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Melanie Klein: Her Work in Context. Continuum International Publishing Group, 2002.
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Melanie Klein: Her Work in Context. Bloomsbury Publishing Plc, 2002.
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Melanie Klein: Her work in context. London: Continuum, 2001.
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Melanie Klein: Her Work in Context. Bloomsbury Publishing Plc, 2002.
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Kommentariĭ k Federalʹnomu zakonu "O schetnoĭ palate Rossiĭskoĭ Federat︠s︡ii": Ot 11 i︠a︡nvari︠a︡ 1995 g. no. 4-FZ : v redakt︠s︡ii Federalʹnykh zakonov ot 10 ii︠u︡li︠a︡ 2002 g. no. 86-FZ, ot 30 ii︠u︡ni︠a︡ 2003 g. no. 86-FZ, ot 29 ii︠u︡ni︠a︡ 2004 g. no. 58-FZ, ot 14 avgusta 2004 g. no. 101-FZ, ot 1 dekabri︠a︡ 2004 g. no. 145-FZ, ot 25 ii︠u︡li︠a︡ 2006 g. no. 128-FZ, ot 2 marta 2007 g. no. 24-FZ, ot 12 apreli︠a︡ 2007 g. no. 49-FZ, ot 21 ii︠u︡li︠a︡ 2007 g. no. 190-FZ, ot 24 ii︠u︡li︠a︡ 2007 g. no. 214-FZ i ot 29 marta 2008 g. no. 29-FZ : postateĭnyĭ. Moskva: Delovoĭ dvor, 2009.
Encontre o texto completo da fonteCapítulos de livros sobre o assunto "2001 g-491"
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Funari, Pedro Paulo A. "A History of Archaeology in Brazil (2001)." In Histories of Archaeology. Oxford University Press, 2008. http://dx.doi.org/10.1093/oso/9780199550074.003.0018.
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The history of archaeology in Brazil has been divided into phases following different criteria. Most authors consider that archaeology should have its own disciplinary history, not tied to the overall political history of the country. A. Prous (1992) identified five periods and A. Mendonça de Souza (1991) followed the same disciplinary history approach, but proposed only four periods. The history of archaeology in Brazil should not, however, be considered independent from Brazilian history. Because the development of archaeology’s practice, theory, and methodology depends directly on the socio-political conditions in a given country, it is possible to relate the social practice of archaeology and political changes. As with any intellectual endeavour, archaeological activities are the result of social conditions and relations prevailing in different periods. Thus we can say that archaeology in Brazil went through seven phases: the colonial period (1500–1822); the Brazilian empire (1822–89); the early republic (1889–1920s); the formative period (1920–49); the inception of university research (1950–64); the military period, and the constitution of an archaeological establishment (1964–85); and current trends, democratic and pluralist archaeology (1985 onwards). There are few references in colonial sources to archaeological sites, although F. Cardim (1925) notes that shell mounds were identified in Brazil by their Tupi name sambaquis as early as 1583, and F. Coelho’s soldiers, as early as 1598, mention rock inscriptions (Prous 1992: 5). However, travellers and writers such as Y. d’Euvreux (1985), G. Soares (1944), G. Carvajal (1942), A. Thevet (1944) and H. Staden (1930), among others, described native inhabitants and their culture, furnishing a lot of data on Indian material culture. Thanks to these sources, it is possible to study native settlements while taking into full account the historic evidence relating to the following areas: the East Amazon basin area, Porro 1992; Taylor 1992; Erikson 1992; Wright 1992; the North Amazon region, Farage and Santilli 1992; Menéndez 1992; Amoroso 1992; the South Amazon area, Perrone-Moisés 1992; Franchetto 1992; Lopes da Silva 1992; the north-east, Paraíso 1992; Dantas, Sampaio, and Carvalho 1992; the south-west, Carvalho 1992; the south, Monteiro 1992; Kern 1982; the entire country, Fausto 1992.
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Taber, Douglass F. "Stereocontrolled C-N Ring Construction: The Pyne Synthesis of Hyacinthacine B 3". In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0054.
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Keiji Maruoka of Kyoto University found (Organic Lett. 2010, 12, 1668) that the diazo amide 1 derived from the Oppolzer sultam condensed with the imine 2 to give the aziridine 3 with high stereocontrol. Andrei K. Yudin of the University of Toronto observed (Angew. Chem. Int. Ed. 2010, 49, 1607) that the unprotected aziridine aldehyde 4, which exists as a mixture of dimers, condensed smoothly with the Ohira reagent 5 to give the alkynyl aziridine 6. David M. Hodgson of the University of Oxford successfully (Angew. Chem. Int. Ed. 2010, 49, 2900) deprotonated the azetidine thioamide 7 to give, after allylation, the azetidine 8. Varinder K. Aggarwal of the University of Bristol devised (Chem. Commun. 2010, 267) a Pd catalyst for the cyclocarbonylation of an alkenyl aziridine 9 to give the β-lactam 10. Iain Coldham of the University of Sheffield used (J. Org. Chem. 2010, 75, 4069) the ligand they had developed to effect enantioselective allylation of the pyrrolidine derivative 11. The corrresponding piperidine worked as well. John P. Wolfe of the University of Michigan established (Organic Lett. 2010, 12, 2322) that the Pd-mediated cyclization of 13 to 15 could be effected with high diastereocontrol. Christopher G. Frost of the University of Bath optimized (Angew. Chem. Int. Ed. 2010, 49, 1825) the tandem Ru-mediated conjugate addition/cyclization of 16 to give 18 in high ee. Barry M. Trost of Stanford University extended (J. Am. Chem. Soc. 2010, 132, 8238) their studies of trimethylenemethane cycloaddition to the ketimine 19, leading to the substituted pyrrolidine 21 in high ee. Pher G. Andersson of Uppsala University optimized (J. Am. Chem. Soc. 2010, 132, 8880) an Ir catalyst for the enantioselective hydrogenation of readily prepared tetrahydropyridines such as 22. Min Shi of the Shanghai Institute of Organic Chemistry devised (J. Org. Chem. 2010, 75, 3935) a Pd catalyst for enantioselective conjugate addition to the prochiral pyridone 24. Xiaojun Huang of Roche Palo Alto prepared (Tetrahedron Lett. 2010, 51, 1554) the monoacid 26 by enantioselective methanolysis of the anhydride. Selective formylation of the ester led to the pyridone 27.
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"Why Women Are Compelled to Worship Dionysos". In Women’s Religions in the Greco-Roman World, editado por Ross Shepard Kraemer, 12. Oxford University PressNew York, NY, 2004. http://dx.doi.org/10.1093/oso/9780195170658.003.0002.
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Abstract Author: Euripides (ca. 485–406 b.c.e.), one of the most famous of the Athenian playwrights, wrote a number of plays that feature Greek women: Medea, Androm ache, Hecuba, Helen, Electra, Iphigenia at Aulis, and Iphigenia in Tauris. He devoted one of the last of his plays, The Bacchae (which posthumously brought him victory at the festival known as the Dionysia in 406 b.c.e.), to the origins and character of women’s worship of the Thracian god Dionysos. Modern scholars have continued to wrestle with the correspondence between Euripides’ representation of Bacchic worship, set in ancient Thebes, and practices current in the late fifth to early fourth centuries b.c.e. (including Athens and elsewhere). Much of Euripides’ description is not significantly at odds with other ancient sources. translation: W. Arrowsmith, The Bacchae, in David Grene and Richmond Lattimore, eds., Greek Tragedies, vol. 3 (Chicago: University of Chicago Press, 1960). text: OCT (G. Murray, 1901–13); E. R. Dodds, Euripides’ “Bacchae,” 2d ed. (Oxford: Clarendon Press, 1970). additional text and translation: LCL (Arthur S. Way, 1912, vol. 3; David Kovacs, 2002). additional translations: There are many English translations of The Bacchae. Recent ones include David Franklin, Euripides’ “Bacchae”: A New Translation and Commentary (Cambridge: Cambridge University Press, 2000); Reginald Gibbons and Charles Segal, Euripides’ “Bakhai” (New York: Oxford University Press, 2001); and C. K. Williams, “The Bacchae” of Euripides: A New Version (New York: Farrar, Straus, Giroux, 1990). Also of interest is G. S. Kirk, The Bacchae (Englewood Cliffs, N.J.: Prentice-Hall, 1970). bibliography: Blessings, 36–49; Susan Guettel Cole, “New Evidence for the Mysteries of Dionysos,” GRBS 21 (1980): 223–38; Synnove Des Bouvrie, “Euripides’ Bakkhai and Maenadism,” Classica et Mediaevalia 48 (1997): 75–114; A. Henrichs, “Greek Maenadism from Olympias to Messalina,” HSCP 82 (1978): 121–60; Eva Keuls, The Reign of the Phallus (New York: Harper and Row, 1985); Valdis Leinieks, The City of Dionysos: A Study of Euripides’ “Bakchai” (Stuttgart: Teubner, 1996); Deborah Lyons, Gender and Immortality: Heroines in Ancient Greek Myth and Cult (Princeton: Princeton University Press, 1997); Nancy Sorkin Rabinowitz, Anxiety Veiled: Euripides and the Traffic in Women (Ithaca, N.Y.: Cornell University Press, 1993).
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Taber, Douglass F. "Advances in Organic Functional Group Transformation". In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0006.
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There have been several significant advances in N-alkylation using alcohols. Matthias Beller of Universität Rostock devised (Angew. Chem. Int. Ed. 2010, 49, 8126) a Ru catalyst for the amination of secondary and benzylic primary alcohols with ammonia. Dieter Vogt of the Eindhoven University of Technology reported (Angew. Chem. Int. Ed. 2010, 49, 8130) related transformations. Pei-Qiang Huang of Xiamen University showed (Chem. Commun. 2010, 46, 7834) that debenzylation of 3 in methanol led to the N-methyl amine 4. Parallel results have been reported with Ir (J. Am. Chem. Soc. 2010, 132, 15108), Au (Chem. Eur. J. 2010, 16, 13965), and Cu (Chem. Lett. 2010, 39, 1182). Peter J. Scammells of Monash University found (J. Org. Chem. 2010, 75, 4806) that demethylation of an N-oxide could be effected with Fe powder. Yao Fu and Qingxiang Guo of the University of Science and Technology of China N-vinylated (Tet. Lett. 2010, 51, 5476) a sulfonamide 7 with vinyl acetate and a Pd catalyst. Acyl amides could also be N-vinylated under these conditions. Hirokazu Urabe of the Tokyo Institute of Technology reported (Org. Lett. 2010, 12, 4137) that the stereodefined secondary sulfonamide of 9 could be displaced by an internal nucleophile, to give the product 11 with inversion of absolute configuration. Teruo Umemoto of IM&T Research devised (J. Am. Chem. Soc. 2010, 132, 18199) the remarkable fluorinating agent 13. In addition to converting secondary alcohols to the corresponding fluorides and ketones to gem-difluorides, 13 cleanly converted the carboxylic acids of 12 to trifluoromethyl groups. Paul G. Williard of Brown University demonstrated (Org. Lett. 2010, 12, 5378) that LDA converted an allyl ether 15 specifically to the (Z)-propenyl ether 16. Phil Lee Ho of Kangwon National University and Sunggak Kim of Nanyang Technological University could add (Angew. Chem. Int. Ed. 2010, 49, 6806) a phosphate to an alkyne 17 to make either the less substituted or the more substituted enol phosphate. Professor Kim reported (J. Org. Chem. 2010, 75, 7928) similar results with the addition of carboxylic acids.
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Taber, Douglass. "Best Synthetic Methods: Functional Group Transformation". In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0007.
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François Morvan of the Université de Montpellier, using the inexpensive dimethyl phosphite, optimized (Tetrahedron Lett. 2008, 49, 3288) the free radical reduction of 1 to 2. Pawan K. Sharma of Kurukshetra University found (Tetrahedron Lett. 2008, 48, 8704) that NaBH4 in the presence of a catalytic amount of RuCl3.xH2 O reduced monosubstituted and disubstituted alkenes, such as 3, to the corresponding alkanes. Note that benzyl ethers were stable to these conditions. Ken Suzuki of Asahi Kasei Chemicals and Shun-Ichi Murahashi of Okayama University of Science established conditions (Angew. Chem. Int. Ed. 2008, 47, 2079) for the oxidation of primary amines such as 5 to oximes. Both ketoximes such as 6 and aldoximes were prepared using this protocol. Primary and secondary alcohols were stable to these conditions. Three noteworthy procedures for the oxidation of an aldehyde to the acid oxidation state were recently reported. Jonathan M. J. Williams of the University of Bath demonstrated (Chem. Commun. 2008, 624) that crotonitrile could serve as the hydrogen acceptor in the oxidation of an aldehyde 7 to the methyl ester 8. Note that isolated alkenes were stable to these conditions. Vikas N. Telvekar the University Institute of Chemical Technology, Mumbai improved (Tetrahedron Lett . 2008, 49, 2213) the oxidative amination of an aldehyde 9 to the nitrile 10. G. Sekar of the Indian Institute of Technology Madras effected (Tetrahedron Lett. 2008, 49, 1083) oxidation of an aldehyde 11 to the acid 12, under conditions that would be expected to not oxidize a primary or secondary alcohol. J. S. Yadav of the Indian Institute of Chemical Technology, Hyderabad observed (Tetrahedron Lett. 2008, 49, 3015) that the activation of a thiophenol 14 with N-chlorosuccimide generated a species that added regioselectively to a ketone 13 to give the thioether 15. Oxidation of the sulfide 15 followed by heating of the resulting sulfoxide would give the enone 16. This appears to be an easily scalable procedure. It is well known that an acid 17 and an amine 18 will condense at elevated temperature to give the amide 20.
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Taber, Douglass. "Organic Functional Group Interconversion: (-)- β -Conhydrine (Barua) and (+)-6'-Hydroxyarenarol (Anderson)". In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0009.
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V. T. Perchyonok and Kellie L. Tuck of Monash University found (Tetrahedron Lett. 2008, 49, 4777) that a concentrated solution of Bu4NCl and H3PO2 in water effected free radical reductions and cyclizations. Stéphane G. Ouellet of Merck Frosst demonstrated (Tetrahedron Lett. 2008, 49, 6707) that an oxazoline such as 3 could be converted to the alcohol 4 by acylation followed by reduction. Elizabeth R. Burkhardt of BASF developed (Tetrahedron Lett. 2008, 49, 5152) a protocol for scalable reductive amination using an easily metered liquid pyridine-borane complex. Mohammad Movassaghi of MIT devised (Angew. Chem. Int. Ed. 2008, 47, 8909) a strategy for conversion of an allylic carbonate 8 by way of the allylic diazene to the terminal alkene 9. Philippe Compain of the Université d’Orleans uncovered (J. Org. Chem. 2008, 73, 8647) a practical procedure for oxidizing an inexpensive aldose such as 10 to the amide 12, a valuable chiral pool starting material. Karl A. Scheidt of Northwestern University extended (Organic Lett. 2008, 10, 4331) activated MnO2 oxidation to saturated aldehydes such as 13, leading to the ester 15. Tohru Fukuyama of the University of Tokyo showed (Organic Lett. 2008, 10, 2259) that halides such as 16 could be oxidized to the oxime 18 with the reagent 17. The product oximes are readily dehydrated to the corresponding nitriles. Chutima Kuhakarn of Mahidol University devised (Synthesis 2008, 2045) a simple protocol for the oxidation of a primary amine such as 19 to the nitrile 20 . Nasser Iranpoor and Habib Firouzabadi of Shiraz University developed (J. Org. Chem. 2008, 73, 4882) the reagent 22 for Mitsunobu coupling. The stereochemical course of this reaction with simple acyclic secondary alcohols such as 21 was not reported. Salvatore D. Lepore of Florida Atlantic University optimized (Angew. Chem. Int. Ed. 2008, 47, 7511) the quisylate 24 for the displacement with retention to give the azide 25. Hideki Yorimitsu and Koichiro Oshima of Kyoto University optimized (J. Am. Chem. Soc. 2008, 130, 11276) a Co catalyst for the conversion of a secondary halide such as 26 to the terminal alkene 27 . Base-mediated elimination gave primarily the internal alkene.
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Taber, Douglass F. "C-O Ring Construction: (-)-Sclerophytin A (Morken), (+)-Dictyosphaeric Acid (Taylor), Goniothalesdiol A (Xie/She), (-)-7-Deoxyloganin (Lupton), (-)-Apicularen A (Uenishi), L-783, 277(Banwell) 100". In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0052.
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In the course of a synthesis of (-)-sclerophytin A 3, James P. Morken of Boston College showed (J. Am. Chem. Soc. 2010, 132, 16380) that Oshima-Utimoto conditions transformed 1 into 2 with high stereo-and regiocontrol. En route to (+)-dictyosphaeric acid 6, Richard J. K. Taylor of the University of York found (Angew. Chem. Int. Ed. 2010, 49, 5574) that the intramolecular Michael cyclization of 4 proceeded smooothly to give 5. Xingang Xie and Xuegong She of Lanzhou University devised (Synlett 2010, 2283) the In-mediated cyclization of 7 with benzaldehyde, to effect an elegant synthesis of goniothalesdiol A 9. The carbene-mediated cyclization of 10 to 11 developed (Org. Lett. 2010, 12, 4836) by David W. Lupton of Monash University set the stage for the synthesis of (-)-7-deoxyloganin 12. Jun’ichi Uenishi of Kyoto Pharmaceutical University showed (Org. Lett. 2010, 12, 4160) that the Pd-mediated cyclization of 13 proceeded with high diastereocontrol. Intramolecular esterification than led to (-)-apicularen A 15. Martin G. Banwell of the Australian National University established (Heterocycles 2010, 82, 313) that LiHMDS was effective for the cyclization of the alkynyl Weinreb amide 16 to 17. Reduction and deprotection completed the synthesis of the resorcylic lactone L-783, 277 18.
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Taber, Douglass F. "Substituted Benzenes: The Kirsch Synthesis of Cybrodol". In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0063.
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Stephen L. Buchwald of MIT established (J. Am. Chem. Soc. 2010, 132, 14076) a Pd-catalyzed protocol for conversion of an aryl triflate 1 to the halide 2. Jie Wu of Fudan University prepared (Tetrahedron Lett. 2010, 51, 6646) aromatic halides from the corresponding carboxylic acids. Yong-Chua Teo of Nanyang Technological University described (Tetrahedron Lett . 2010, 51, 3910) the Mn-mediated conversion of 3 to 5, suggesting a benzyne intermediate. Takanori Shibata of Waseda University effected (Synlett 2010, 2601) the direct Ru-mediated coupling of aryl halides with amines, and Paul Helquist of the University of Notre Dame prepared (J. Org. Chem. 2010, 75, 4887) anilines by coupling aryl halides with NaN3 . Chao-Jun Li of McGill University devised (Tetrahedron Lett. 2010, 51, 5486) the Pd-catalyzed decarbonylative Heck coupling of 6 with 7 to give 8. Mats Larhed of Uppsala University showed (Angew. Chem. Int. Ed. 2010, 49, 7733) that Pd could also catalyze the decarboxylative coupling of an aromatic acid 9 with a nitrile to give the ketone 10. Dennis G. Hall of the University of Alberta found (Tetrahedron Lett. 2010, 51, 4256) that an areneboronic acid could promote the Zr-catalyzed ortho condensation of a phenol 11 with an aldehyde, leading to 12, which could then be carried on to a range of other products. Professor Hall also showed (Angew. Chem. Int. Ed. 2010, 49, 2883) that areneboronic acids are stable to many standard organic transformations, and that the product boronic acids can be readily purified by extraction into sorbitol/Na2CO3. Professor Buchwald reported (J. Am. Chem. Soc. 2010, 132, 14073) an optimized source of Pd for the Suzuki-Miyaura coupling, allowing the room-temperature participation even of unstable boronic acids such as 13. Wing-Yiu Yu of the Hong Kong Polytechnic University observed (J. Am. Chem. Soc. 2010, 132, 12862) that 17 was an effective donor for the Pd-catalyzed ortho C-H amination of 16. Nicholas C. O. Tomkinson of Cardiff University uncovered (Synlett 2010, 2471) the facile rearrangement of 19 to 20. Professor Buchwald described (J. Am. Chem. Soc. 2010, 132, 9990) the coupling of 21, prepared from the aryl halide, with 22 to give the benzofuran 23.
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Silveira, Kênia Dayane Aparecida, João Batista Guerra Roquetti, Adriano Carvalho Rodrigues, Julia Ferreira Duarte, Willian Antônio Dos Santos, Murilo Mariano Prates Costa, Francielton Antônio Da Costa, Eduardo Marques Costa, Érika Andressa Silva e Franciane Diniz Cogo. "TEORES FOLIARES DE NUTRIENTES, CLOROFILAS E PARÂMETROS FITOTÉCNICOS DE CAFEEIROS EM FUNÇÃO DE FONTES DE FÓSFORO". In Manejo Fisiológico e Nutricional de Plantas: abordagens práticas na agricultura - Volume 2, 99–111. Editora Científica Digital, 2024. http://dx.doi.org/10.37885/240115434.
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Objetivo: estudar as respostas de diferentes fontes comerciais e doses de fósforo no desenvolvimento inicial de cafeeiros. Métodos: O experimento foi desenvolvido em Latossolo Vermelho seguindo delineamento blocos ao acaso, avaliando seis tratamentos constituídos a partir da combinação de dois produtos comerciais: P (49% P2O5) e T (28% P2O5) e três doses: 56, 84 e 129 g m-1 e T: 100, 150 e 200 g m-1, respectivamente. Aos 6 e 11 meses após o transplantio ou emergência foram tomadas medidas das alturas das plantas, e após 15 meses foram realizadas análises dos teores de clorofila e foliares. Resultados: Nos períodos avaliados, 04/06/2022 e 15/11/2022 não foram observados efeitos dos produtos ou doses testadas no crescimento dos cafeeiros. Em março de 2023 não foram observados efeitos dos produtos na nutrição foliar dos cafeeiros. Todavia, foram observados maiores valores do índice de clorofila b utilizando o produto T, ou seja, esse produto comercial, em qualquer dose, elevou os teores de clorofila B. Conclusão: As fontes e doses de fósforo influenciaram apenas os teores da clorofila B.
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Taber, Douglass F. "Oxidation and Reduction". In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0011.
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Kiyotomi Kaneda of Osaka University devised (Angew. Chem. Int. Ed. 2010, 49, 5545) gold nanoparticles that efficiently deoxygenated an epoxide 1 to the alkene 2. Robert G. Bergman of the University of California, Berkeley, and Jonathan A. Ellman, now of Yale University, reported (J. Am. Chem. Soc. 2010, 132, 11408) a related protocol for deoxygenating 1,2-diols. Dennis A. Dougherty of Caltech established (Org. Lett. 2010, 12, 3990) that an acid chloride 3 could be reduced to the phosphonate 4. Pei-Qiang Huang of Xiamen University effected (Synlett 2010, 1829) reduction of an amide 5 by activation with Tf2O followed by reduction with NaBH4. André B. Charette of the Université de Montreal described (J. Am. Chem. Soc. 2010, 132, 12817) parallel results with Tf2O/Et3SiH. David Milstein of the Weizmann Institute of Science devised (J. Am. Chem. Soc. 2010, 132, 16756) a Ru catalyst for the alternative reduction of an amide 7 to the amine 8 and the alcohol 9. Shi-Kai Tian of the University of Science and Technology of China effected (Chem. Commun. 2010, 46, 6180) reduction of a benzylic sulfonamide 10 to the hydrocarbon 11. Thirty years ago, S. Yamamura of Nagoya University reported (Chem. Commun. 1967, 1049) the efficient reduction of a ketone to the corresponding methylene with Zn/HCl. Hirokazu Arimoto of Tohoku University established (Tetrahedron Lett. 2010, 51, 4534) that a modified Zn/TMSCl protocol could be used following ozonolysis to effect conversion of an alkene 12 to the methylene 13. José Barluenga and Carlos Valdés of the Universidad de Oviedo effected (Angew. Chem. Int. Ed. 2010, 49, 4993) reduction of a ketone to the ether 16 by way of the tosylhydrazone 14. Kyoko Nozaki and Makoto Yamashita of the University of Tokyo and Dennis P. Curran of the University of Pittsburgh found (J. Am. Chem. Soc. 2010, 132, 11449) that the hydride 18 (actually a complex dimer) could effect the direct reduction of a halide 17 and also function as the hydrogen atom donor for free radical reduction and as the hydride donor for the Pd-mediated reduction of an aryl halide.
Trabalhos de conferências sobre o assunto "2001 g-491"
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Iovene, Maddalena, Graciela Fernandéz De Córdova, Ombretta Romice e Sergio Porta. "Towards Informal Planning: Mapping the Evolution of Spontaneous Settlements in Time." In 24th ISUF 2017 - City and Territory in the Globalization Age. Valencia: Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/isuf2017.2017.5441.
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Maddalena Iovene¹, Graciela Fernandéz De Córdova2, Ombretta Romice¹, Sergio Porta¹ ¹Urban Design Studies Unit (UDSU). Department of Architecture. University of Strathclyde. 75 Montrose Street, Glasgow, G11XJ, UK. 2Centro de Investigación de la Arquitectura y la Ciudad (CIAC), Departamento de Arquitectura, PUCP. Av. Universitaria 1801, 32 San Miguel, Lima, Peru. E-mail: maddalena.iovene@strath.ac.uk, gdcfernandez@pucp.edu.pe, ombretta.r.romice@strath.ac.uk, sergioporta@strath.ac.uk Keywords (3-5): Informal Settlement, Peru, Lima, Model of Change, Urban Morphology Conference topics and scale: Reading and Regenerating the Informal City Cities are the largest complex adaptive system in human culture and have always been changing in time according to largely unplanned patterns of development. Though urban morphology has typically addressed studies of form in cities, with emphasis on historical cases, diachronic comparative studies are still relatively rare, especially those based on quantitative analysis. As a result, we are still far from laying the ground for a comprehensive understanding of the urban form’s model of change. However, developing such understanding is extremely relevant as the cross-scale interlink between the spatial and social-economic dynamics in cities are increasingly recognized to play a major role in the complex functioning of urban systems and quality of life. We study the urban form of San Pedro de Ate, an informal settlement in Lima, Peru, along its entire cycle of development over the last seventy years. Our study, conducted through a four-months on-site field research, is based on the idea that informal settlements would change according to patterns similar to those of pre-modern cities, though at a much faster pace of growth, yet giving the opportunity to observe the evolution of an urban organism in a limited time span. To do so we first digitalize aerial photographs of five different time periods (from 1944 to 2013), to then conduct a typo-morphological analysis at five scales: a) unit, b) building, c) plot, d) block, and e) settlement (comprehensive of public spaces and street network). We identify and classify patterns of change in the settlement’s urban structure using recognised literature on pre-modern cities, thus supporting our original hypothesis. We then suggest a unitary model of analysis that we name Temporal Settlement Matrix (TSM). Reference List Caniggia, G., & Maffei, G. L. (2008). Lettura dell’edilizia di base (Vol. 215). Alinea Editrice. Conzen, M. R. G. (1958). The growth and character of Whitby. A Survey of Whitby and the Surrounding Area, 49–89. Hernández, F., Kellett, P. W., & Allen, L. K. (2010). Rethinking the informal city: critical perspectives from Latin America (Vol. 11). Berghahn Books. Kropf, K. (2009). Aspects of urban form. Urban Morphology, 13(2), 105–120. Muratori, S. (1960). Studi per una operante storia urbana di Venezia. Palladio, 1959, 1–113. 22. Porta, S., Romice, O., Maxwell, J. A., Russell, P., & Baird, D. (2014). Alterations in scale: patterns of change in main street networks across time and space. Urban Studies, 51(16), 3383–3400. Watson, V. (2009). “The planned city sweeps the poor away…”: Urban planning and 21st century urbanisation. Progress in Planning, 72(3), 151–193. Whitehand, J. W. R. (2001). Changing suburban landscapes at the microscale. Tijdschrift Voor Economische En Sociale Geografie, 92(2), 164–184.
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Волкова, Н. В., e Н. В. Солнцева. "ГЕНЕТИЧЕСКИЕ И КЛИНИКО-МЕТАБОЛИЧЕСКИЕ ОСОБЕННОСТИ У ДЕТЕЙ С АУТОИММУННЫМ ПОЛИГЛАНДУЛЯРНЫМ СИНДРОМОМ 3А ТИПА". In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-281.
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ЦЕЛЬ: определить значимые генетические и клиническо-метаболические факторы аутоиммунных заболеваний щитовидной железы у детей с сахарным диабетом (СД) 1 типа.
МАТЕРИАЛЫ И МЕТОДЫ: в исследование включено 48 детей с сочетанием СД 1 типа и аутоиммунными заболеваниями щитовидной железы (ЩЖ) (основная группа; возраст 12,5 (10,4; 15,4); стаж СД 1 типа
4,2 (1,3; 6,5) лет; у 45 детей отмечено сочетание СД 1 типа с аутоиммунным тиреоидитом, у 3 пациентов –
с болезнью Грейвса) и 99 пациентов СД 1 типа (группа сравнения; возраст 11,6 (9,1; 14,5) лет; стаж СД 1 типа
3,8 (1,6; 6,3) лет). Группы сопоставимы по возрасту (р=0,095) и стажу СД 1 типа (p=0,967).
Проведена оценка роста и индекса массы тела с использованием z-критерия (ВОЗ, 2007 г.). Определение
содержания тиреотропного гормона, свободного тироксина, антител к тиреоидной пероксидазе,
25-гидроксихолекальциферола (D (25(ОН)D)), антител к цинковому транспортеру (ZnT8), глутаматдекарбоксилазе (GAD) в сыворотке крови проведено методом иммуноферментного анализа. Для генотипирования однонуклеотидных полиморфизмов c.49A>G и CT60 гена цитотоксического рецептора Т-лимфоцитов
(CTLA4) применена методика аллельспецифичной полимеразной цепной реакции с помощью линейных
разрушаемых проб (TaqMan). Статистическая обработка результатов выполнена с помощью программ
Statistica 10 и Excel 2010. Различия считали статистически значимыми при значениях р<0,05.
РЕЗУЛЬТАТЫ: выявлены достоверные различия уровней 25(ОН)D (р=0,034) между пациентами исследуемых групп. Отмечена большая распространённость тяжёлого дефицита витамина D у детей с АПС 3 типа,
по сравнению с изолированным СД 1 типа (ОШ = 3,4 (1,3-8,8), р=0,009). Установлена слабая обратная связь
показателя 25(ОН)D с уровнем антител к ТПО (rs= -0,20, р=0,020).
Выявлены статистически значимо более высокие значения медианы уровней антител к ZnT8 у детей
основной группы со стажем СД 1 типа менее 3 лет по сравнению с группой сравнения (р=0,024). Группы
отличались по доле пациентов с уровнем антител к ZnT8>450 МЕ/мл (р=0,011). Обнаружены достоверные
отличия уровней антител к GAD между группами у пациентов со стажем СД 1 типа более 3 лет (р=0,004),
группы достоверно отличались по доле пациентов с уровнем антител к GAD65>15 МЕ/мл (р=0,010).
При сравнении частоты генотипов по локусу c.49A>G гена CTLA4 установлено, что наличие в генотипе
аллеля G (генотипы AG и GG) увеличивает шансы развития аутоиммунной патологии ЩЖ у детей с СД
1 типа (ОШ = 2,8 (1,1-7,2), р=0,033). Обнаружено значимое различие по частоте аллелей по локусу CT60 гена
CTLA4 между группами: в основной группе отмечена большая распространённость аллеля G, по сравнению
с группой сравнения (р=0,038).
ВЫВОДЫ:
1. Установлена ассоциация аутоиммунных тиреоидных заболеваний с антителами к ZnT8 у детей со стажем
СД 1 типа менее 3 лет и антителами к GAD65 у пациентов со стажем заболевания более 3 лет.
2. Отмечено более высокое распространение тяжелого дефицита витамина D у детей с сочетанной патологией ЩЖ по сравнению с пациентами с изолированным СД 1 типа. Выявлена обратная связь уровня
антител к ТПО и 25(ОН)D.
3. Установлена более высокая частота аллеля G по локусу СТ60 и генотипов АG и GG по локусу c.49A>G
гена CTLA4 у детей с полигландулярным аутоиммунным поражением по сравнению со сверстниками,
имеющими СД 1 типа.
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De, Ashoke, e Sumanta Acharya. "Large Eddy Simulation of Premixed Combustion With a Thickened-Flame Approach". In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-51320.
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A Thickened Flame (TF) modeling approach is combined with a Large Eddy Simulation (LES) methodology to model premixed combustion and the accuracy of these model predictions is evaluated by comparing with the piloted premixed stoichiometric methane-air flame data of Chen et al. [Combust. Flame 107 (1996) 223–226] at a Reynolds number Re = 24,200. In the TF model, the flame front is artificially thickened to resolve it on the computational LES grid. Since the flame front is resolved, the combustion chemistry can be incorporated directly without closure approximations for the reaction rate. The response of the thickened flame to turbulence is taken care of by incorporating an efficiency function in the governing equations. The efficiency function, which is also known as a sub-grid flame wrinkling parameter, is a function of local turbulence and of the premixed flame characteristics, such as laminar flame speed and thickness. Three variants of the TF model are examined: the original Thickened Flame model, the Power-law flame wrinkling model, and the dynamically modified TF model. Reasonable agreement is found when comparing predictions with the experimental data and with computations reported using a probability distribution function (PDF) modeling approach by Lindstedt et al. [Combust. Flame 145 (2006) 495–511] and G-equation approach by Duchamp et al. [Annual Research Briefs, CTR (2000) 105–116].
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Vinatoru, Mircea. "MICROWAVE AND ULTRASOUNDS TOGETHER – A CHALLENGE". In Ampere 2019. Valencia: Universitat Politècnica de València, 2019. http://dx.doi.org/10.4995/ampere2019.2019.9822.
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The literature related to microwave and ultrasound working simultaneously is rather infrequent. The reason is obvious: microwave irradiation is of electromagnetic origin while ultrasound is a mechanical vibration energy. Moreover, the optimal settings for ultrasound propagation throughout a reaction media do not coincide with the conditions required for application of microwaves. Therefore, the challenge is to find a way to best combination of these sources of energy into one apparatus to allow researchers to take advantage of the features of each technology. The oldest paper describing such a combination – microwave and ultrasound is having just 20 years [1] and describe an apparatus which uses a probe system delivering ultrasound through decalin to a vessel holding the reagents dipped in the MW cavity (fig. 1a). Another possibility using a normal MW oven is described by Peng [2] (fig.1b), but this setup is having radiation leakage problems and needs a proper protection. Ragaini et all proposed another type of setup [3] (fig. 1c), not easy to reproduce, but describing calibration and parameters which show an additive increase of thermal energy delivered when MW and US works simultaneous. Insert here uploaded pictures Figure 1. Some MW-US simultaneous setups Few years ago, Cravotto and Cintas [4], disccussed for the first time the potential of using MW and US in sequential or tandem setups. Their paper discuss all possible setups for using mostly glass probe for devlivery of ultrasonic energy or classical setup (fig. 1a). Slowly the concept gain popularity and the paper of Lionelly and Mason [5] prompts to the potential industrial applications, naming the combination of microwave with ultrasound a hybrid technology. The challenge in using this “hybrid technology” is to find a vesatile and reproducible apparatus able to deliver both microwave and ultrasound at a full controlable parameters. In our laboratory we have and use the setup like in the fig. 1a, but the ultrasonic energy is delivered by an ultrasonic cleaning device attached to microwave device (SAIREM Miniflow 200SS). To achieve the above mentioned outcome launched a project to build a device which could work with MW and US in tandem (as Cravotto mentioned [4]) using an US device able to deliver more than a single ultrasonic frequency at a full controlled power. It is our believe that such a device could significantly contribute to MW-US tandem equipment development. Based on our expertise and potential proposed interaction of US with reagents [6] we will investigate the influence (if any) of ultrasound upon MW field. In this paper we will present the earlier results of “Tandem Microwave Ultrasound” energy influence on chemical reagents. References 1. Lagha, A., et al., Analusis, 1999. 27(5): p. 452-457. 2. Peng, Y. and G. Song, Green Chemistry, 2001. 3(6): p. 302-304. 3. Ragaini, V., et al., Ultrasonics Sonochemistry, 2012. 19(4): p. 872-876. 4. Cravotto, G. and P. Cintas, Chemistry - A European Journal, 2007. 13(7): p. 1902-1909. 5. Leonelli, C. and T.J. Mason, Chemical Engineering and Processing: Process Intensification, 2010. 49(9): p. 885-900. 6. Vinatoru, M. and T.J. Mason, Ultrasonics Sonochemistry, 2018.
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Ettema, Roelof, Goran Gumze, Katja Heikkinen e Kirsty Marshall. "European Integrated Care Horizon 2020: increase societal participation; reduce care demands and costs". In CARPE Conference 2019: Horizon Europe and beyond. Valencia: Universitat Politècnica València, 2019. http://dx.doi.org/10.4995/carpe2019.2019.10175.
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BackgroundCare recipients in care and welfare are increasingly presenting themselves with complex needs (Huber et al., 2016). An answer to this is the integrated organization of care and welfare in a way that personalized care is the measure (Topol, 2016). The reality, however, is that care and welfare are still mainly offered in a standardized, specialized and fragmented way. This imbalance between the need for care and the supply of care not only leads to under-treatment and over-treatment and thus to less (experienced) quality, but also entails the risk of mis-treatment, which means that patient safety is at stake (Berwick, 2005). It also leads to a reduction in the functioning of citizens and unnecessary healthcare cost (Olsson et al, 2009).Integrated CareIntegrated care is the by fellow human beings experienced smooth process of effective help, care and service provided by various disciplines in the zero line, the first line, the second line and the third line in healthcare and welfare, as close as possible (Ettema et al, 2018; Goodwin et al, 2015). Integrated care starts with an extensive assessment with the care recipient. Then the required care and services in the zero line, the first line, the second line and / or the third line are coordinated between different care providers. The care is then delivered to the person (fellow human) at home or as close as possible (Bruce and Parry, 2015; Evers and Paulus, 2015; Lewis, 2015; Spicer, 2015; Cringles, 2002).AimSupport societal participation, quality of live and reduce care demand and costs in people with complex care demands, through integration of healthcare and welfare servicesMethods (overview)1. Create best healthcare and welfare practices in Slovenia, Poland, Austria, Norway, UK, Finland, The Netherlands: three integrated best care practices per involved country 2. Get insight in working mechanisms of favourable outcomes (by studying the contexts, mechanisms and outcomes) to enable personalised integrated care for meeting the complex care demand of people focussed on societal participation in all integrated care best practices.3. Disclose program design features and requirements regarding finance, governance, accountability and management for European policymakers, national policy makers, regional policymakers, national umbrella organisations for healthcare and welfare, funding organisations, and managers of healthcare and welfare organisations.4. Identify needs of healthcare and welfare deliverers for creating and supporting dynamic partnerships for integrating these care services for meeting complex care demands in a personalised way for the client.5. Studying desired behaviours of healthcare and welfare professionals, managers of healthcare and welfare organisations, members of involved funding organisations and national umbrella organisations for healthcare and welfare, regional policymakers, national policy makers and European policymakersInvolved partiesAlma Mater Europaea Maribor Slovenia, Jagiellonian University Krakow Poland, University Graz Austria, Kristiania University Oslo Norway, Salford University Manchester UK, University of Applied Sciences Turku Finland, University of Applied Sciences Utrecht The Netherlands (secretary), Rotterdam Stroke Service The Netherlands, Vilans National Centre of Expertise for Long-term Care The Netherlands, NIVEL Netherlands Institute for Health Services Research, International Foundation of Integrated Care IFIC.References1. Berwick DM. The John Eisenberg Lecture: Health Services Research as a Citizen in Improvement. Health Serv Res. 2005 Apr; 40(2): 317–336.2. Bruce D, Parry B. Integrated care: a Scottish perspective. London J Prim Care (Abingdon). 2015; 7(3): 44–48.3. Cringles MC. Developing an integrated care pathway to manage cancer pain across primary, secondary and tertiary care. International Journal of Palliative Nursing. 2002 May 8;247279.4. Ettema RGA, Eastwood JG, Schrijvers G. Towards Evidence Based Integrated Care. International journal of integrated care 2018;18(s2):293. DOI: 10.5334/ijic.s22935. Evers SM, Paulus AT. Health economics and integrated care: a growing and challenging relationship. Int J Integr Care. 2015 Jun 17;15:e024.6. Goodwin N, Dixon A, Anderson G, Wodchis W. Providing integrated care for older people with complex needs: lessons from seven international case studies. King’s Fund London; 2014.7. Huber M, van Vliet M, Giezenberg M, Winkens B, Heerkens Y, Dagnelie PC, Knottnerus JA. Towards a 'patient-centred' operationalisation of the new dynamic concept of health: a mixed methods study. BMJ Open. 2016 Jan 12;6(1):e010091. doi: 10.1136/bmjopen-2015-0100918. Lewis M. Integrated care in Wales: a summary position. London J Prim Care (Abingdon). 2015; 7(3): 49–54.9. Olsson EL, Hansson E, Ekman I, Karlsson J. A cost-effectiveness study of a patient-centred integrated care pathway. 2009 65;1626–1635.10. Spicer J. Integrated care in the UK: variations on a theme? London J Prim Care (Abingdon). 2015; 7(3): 41–43.11. Topol E. (2016) The Patient Will See You Now. The Future of Medicine Is in Your Hands. New York: Basic Books.
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Adam, Moritz, Heather J. Andres e Kira Rehfeld. "The role of dynamic sea ice in a simplified general circulation model used for palaeoclimate studies". In VI ECCOMAS Young Investigators Conference. València: Editorial Universitat Politècnica de València, 2021. http://dx.doi.org/10.4995/yic2021.2021.12383.
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AbstractObservational records provide a strong basis for constraining sea ice models within a narrow range of climate conditions. Given current trends away from these conditions, models need to be tested over a wider range of climate states. The past provides many such examples based on paleoclimate data, including abrupt tipping points. However, the millennial-duration of typical paleoclimatesimulations necessitates balancing the inclusion and sophistication of model processes against computational cost. We investigate the impact on climate mean states and variability of introducing sea ice dynamics into the simplified general circulation model PlaSim-LSG [1-3].Considering the technical constraints of PlaSim-LSG, we choose to integrate a modied version of the MITgcm's dynamical sea ice component [4, 5] into the model setup. We adapt the component to the structure and parallelization scheme of PlaSim-LSG, validate the physical consistency and stability of the component, and evaluate the impact of sea ice dynamics onto the simulated climate from decadal to millennial time scales. Specifically, we compare climatologies, variability and scaling of the extended model to control simulations of the preexisting setups, and quantify how additional sea ice dynamics affect well-known climatic biases of the PlaSim model family.With our extended PlaSim-LSG model we aim at capturing the key small-scale sea ice processes that are important to past climate tipping points while maintaining model efficiency for millennial simulations. Sea ice is a key component of coupled atmosphere-ocean processes that led to large-amplitude, abrupt climate variability in the past [6-8]. Therefore, the extended model can be usedto investigate the role of sea ice for such oscillations. This facilitates the understanding of processes that lead to current mismatches between palaeoclimate data and simulations, and that impact thesimulated surface climate variability [9].References[1] K. Fraedrich et al. Meteorol. Z. 14.3 (2005), 299-304. doi: 10.1127/0941-2948/2005/0043.[2] F. Lunkeit et al. Tech. rep. 2011. url: https://www.mi.uni-hamburg.de/en/arbeitsgruppen/theoretische-meteorologie/modelle/sources/psreferencemanual-1.pdf.[3] H. J. Andres et al. Clim. Past 15.4 (2019), 1621-1646. doi: 10.5194/cp-15-1621-2019.[4] J. Zhang et al. J. Geophys. Res. 102.4 (1997), 412-415.[5] M. Losch et al. Ocean Model. 33.1-2 (2010), 129-144. doi: 10.1016/j.ocemod.2009.12.008.[6] T. M. Dokken et al. Paleoceanography 28.3 (2013), 491-502. doi: 10.1002/palo.20042.[7] G. Vettoretti et al. Geophys. Res. Lett. 43.10 (2016), 5336-5344. doi: 10.1002/2016GL068891.[8] C. Li et al. Quat. Sci. Rev. 203 (2019), 1-20. doi: 10.1016/j.quascirev.2018.10.031.[9] N. Weitzel et al. presented at Fall Meeting AGU. 2020. url: https://agu.confex.com/agu/fm20/webprogram/Paper739241.html.
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Zhang, Zhipeng, Xiang Liu e Zheyong Bian. "Analysis of Restricted Speed Related Train Accidents in the United States, 2000 to 2016". In 2018 Joint Rail Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/jrc2018-6129.
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Railroads contribute to the national economy by carrying over 40% of intercity freight ton-miles in the United States. Train accidents cause damage to infrastructure and rolling stock, disrupt operations, and have the potential to result in casualties and damage the environment. A clear understanding and analysis of accident risk based on historical accidents can support the development and prioritization of effective accident prevention strategies. While extensive previous studies have focused on the safety risks associated with a variety of train operation conditions, much less work has been undertaken to evaluate train risk and safety under restricted speeds. As defined in 49 CFR 236 Subpart G, restricted speed is a speed that permits stopping within one-half the range of vision, but not exceeding 20 miles per hour. Nevertheless, some severe accidents at restricted speeds occurred in the last few years and are also highlighted in both NTSB and FRA reports. In this paper, we develop a quantitative analysis of restricted-speed accidents occurring between 2000 and 2016, based on the data from the U.S. Federal Railroad Administration. While overall accident rates have been proven to decline in prior studies, the preliminary results show that the rate of train accidents under restricted speeds fluctuates in the study period, without a significant increasing or decreasing trend. Furthermore, the distribution of restricted-speed accident severity, accident risk, and other pertinent characteristics are covered in this study.
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Muric, Kenan, Per Tunestal e Ingemar Magnusson. "Medium and High Load Performance of Partially Premixed Combustion in a Wave-Piston Multi-Cylinder Engine With Diesel and PRF70 Fuel". In ASME 2018 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icef2018-9568.
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European and US emission legislation on diesel compression ignition engines has pushed for the development of new types of combustion concepts to reduce hazardous pollutants and increase fuel efficiency. Partially premixed combustion (PPC) has been proposed as one solution to future restrictions on emissions while providing high gross indicated efficiency. The conceptual idea is that the time for the mixing between fuel and air will be longer when ignition delay is increased by addition of high amounts of exhaust gas recirculation (EGR). Increased air-fuel mixing time will lead to lower soot emissions and the high EGR rates will reduce both NOx emissions and combustion flame temperature, which decreases the overall heat transfer. Previous research in heavy-duty gasoline PPC has mostly focused on emissions and efficiency at low and medium load in single-cylinder engines. In this paper a Volvo D13 heavy-duty single-stage VGT engine with a newly developed Wave piston was run at medium and high engine load with a variation in fuel injection pressure. The Wave piston was specifically designed to enhance air-fuel mixing and increase combustion velocity. Two fuels were used in the experiments, PRF70 and Swedish MK1 diesel. Soot-NOx trade-off, combustion characteristics and efficiency were compared for both fuels at 1000 and 2000 Nm engine torque. The results show that at high load the combustion behavior with respect to rate of heat release and heat transfer is very similar between the fuels and no major difference in indicated efficiency could be observed. Peak gross indicated efficiencies were reported to be around 49 % for both fuels at 1000 Nm and slightly above 50 % at 2000 Nm. The new Wave piston made it possible to obtain 1 g/kWh engine-out NOx emissions while still complying with Euro VI legislation for particulate emissions. Soot emissions were generally lower for PRF70 compared to MK1 diesel. We could also conclude that gas exchange performance is a major issue when running high load PPC where high Λ and EGR is required. The single-stage VGT turbocharger could not provide sufficient boost to keep Λ above 1.3 at high EGR rates. This penalized combustion efficiency and soot emissions when reaching Euro VI NOx emission levels (0.3–0.5 g/kWh).
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Laws, A. D., e Y. C. Lee. "Thermal and Structural Analysis of a Suspended Physics Package for a Chip-Scale Atomic Clock". In ASME 2007 InterPACK Conference collocated with the ASME/JSME 2007 Thermal Engineering Heat Transfer Summer Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ipack2007-33013.
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Power dissipation for chip scale atomic clocks (CSAC) is one of the major design considerations. 12 mW of the 30 mW power budget is for temperature control of the vertical-cavity surface-emitting laser (VCSEL) and the alkali-metal vapor cell, each must be maintained at 70±0.1°C even over large ambient temperature variations of 0°C to 50°C. The physics package of a CSAC device is composed of the cell, VCSEL and optical components. This package is heated to 70±0.1°C, but must be very well insulated to dissipate less than 12 mW. To create such a high level of insulation the physics package is enclosed in a gold coated vacuum package and is suspended on a specially designed Cirlex structure. The thermal performance of the suspended physics package has been evaluated by measuring the total thermal resistance from a mockup package with and without an enclosure. Without and enclosure the resistance was found to be 1.07°C/mW. With the enclosure the resistance increases to 1.71°C/mW. These two cases were modeled using FEA, which was found to match well. A FEA model of the real design of the enclosed, suspended physics package was then modeled an was found to have a thermal resistance of 6.28°C/mW, which meets the project requirements. The structural performance of the physics package was measured by shock testing the physics package mockup and recording the response with a high speed video camera. The shock testes were modeled using dynamic FEA and were found to match the measured displacements well. A FEA model of the real design of the physics package was created and it was found that the package will survive an 1800 g shock of any duration in any direction without exceeding the Cirlex yield stress, 49 MPa. In addition the package will survive a 10,000 g shock of any duration in any direction without exceeding the Cirlex tensile stress, 229 MPa.
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Arndt, Mark W., e Stephen M. Arndt. "Test Results: Vehicle Responses to Simulated Drag Caused by Front Tire Tread Detachment — The Effect of Scrub Radius and Speed". In ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/imece2018-87609.
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The effects of reduced kingpin offset distance at the ground (scrub radius) and speed were evaluated under controlled test conditions simulating front tire tread detachment drag. While driving in a straight line at target speeds of 50, 60, or 70 mph with the steering wheel locked, the drag of a tire tread detachment was simulated by applying the left front brake with a pneumatic actuator. The test vehicle was a 2001 dual rear wheel four-wheel-drive Ford F350 pickup truck with an 11,500 lb. GVWR. The scrub radius was tested at the OEM distance of 125 mm (Δ = 0) and at reduced distances of 49 mm (Δ = −76) and 11 mm (Δ = −114). The average steady state responses at 70 mph with the OEM scrub radius were: steering torque = −24.5 in-lb; slip angle = −3.8 deg; lateral acceleration = −0.47 g; yaw rate = −8.9 deg/sec; lateral displacement after 0.75 seconds = 3.1 ft and lateral displacement after 1.5 seconds = 13.1 ft. At the OEM scrub radius, responses that increased linearly with speed included: slip angle (R2 = 0.84); lateral acceleration (R2 = 0.93); yaw rate (R2 = 0.73) and lateral displacement (R2 = 0.59 and R2 = 0.87, respectively). At the OEM scrub radius, steer torque decreased linearly with speed (R2 = 0.76) and longitudinal acceleration had no linear relationship with speed (R2 = 0.09). At 60 mph and 70 mph for both scrub radius reductions, statistically significant decreases (CI ≥ 95%) occurred in average responses of steer torque, slip angle, lateral acceleration, yaw rate, and lateral displacement. At 50 mph, reducing the OEM scrub radius to 11 mm resulted in statistically significant decreases (CI ≥ 95%) in average responses of steer torque, lateral acceleration, yaw rate and lateral displacement. At 50 mph the average slip angle response decreased (CI = 87%) when the OEM scrub radius was reduced to 11 mm.