Gotowa bibliografia na temat „X-chromosome inactivation”
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Artykuły w czasopismach na temat "X-chromosome inactivation"
Cattanach, Bruce M., i Colin V. Beechey. "Autosomal and X-chromosome imprinting". Development 108, Supplement (1.04.1990): 63–72. http://dx.doi.org/10.1242/dev.108.supplement.63.
Pełny tekst źródłaSado, Takashi, i Takehisa Sakaguchi. "Species-specific differences in X chromosome inactivation in mammals". REPRODUCTION 146, nr 4 (październik 2013): R131—R139. http://dx.doi.org/10.1530/rep-13-0173.
Pełny tekst źródłaRastan, Sohaila, i Elizabeth J. Robertson. "X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation". Development 90, nr 1 (1.12.1985): 379–88. http://dx.doi.org/10.1242/dev.90.1.379.
Pełny tekst źródłaMigeon, Barbara R. "X chromosome inactivation". Genome 31, nr 1 (1.01.1989): 464. http://dx.doi.org/10.1139/g89-083.
Pełny tekst źródłaLyon, Mary F. "X-chromosome inactivation". Current Biology 9, nr 7 (kwiecień 1999): R235—R237. http://dx.doi.org/10.1016/s0960-9822(99)80151-1.
Pełny tekst źródłaMalcore, Rebecca M., i Sundeep Kalantry. "A Comparative Analysis of Mouse Imprinted and Random X-Chromosome Inactivation". Epigenomes 8, nr 1 (10.02.2024): 8. http://dx.doi.org/10.3390/epigenomes8010008.
Pełny tekst źródłaLyon, M. F. "X Chromosome Inactivation and Imprinting". Acta geneticae medicae et gemellologiae: twin research 45, nr 1-2 (kwiecień 1996): 85. http://dx.doi.org/10.1017/s0001566000001148.
Pełny tekst źródłaShevchenko, Alexander I., Elena V. Dementyeva, Irina S. Zakharova i Suren M. Zakian. "Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals". International Journal of Developmental Biology 63, nr 3-4-5 (2019): 223–33. http://dx.doi.org/10.1387/ijdb.180376as.
Pełny tekst źródłaTukiainen, Taru, Alexandra-Chloé Villani, Angela Yen, Manuel A. Rivas, Jamie L. Marshall, Rahul Satija, Matt Aguirre i in. "Landscape of X chromosome inactivation across human tissues". Nature 550, nr 7675 (12.10.2017): 244–48. http://dx.doi.org/10.1038/nature24265.
Pełny tekst źródłaZlotorynski, Eytan. "X-chromosome inactivation unravelled". Nature Reviews Molecular Cell Biology 16, nr 6 (8.05.2015): 325. http://dx.doi.org/10.1038/nrm3998.
Pełny tekst źródłaRozprawy doktorskie na temat "X-chromosome inactivation"
Norris, Dominic Paul. "X chromosome inactivation in the mouse". Thesis, Open University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282142.
Pełny tekst źródłaBenjamin, Don. "Molecular studies of human X chromosome inactivation". Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318784.
Pełny tekst źródłaPaterno, Gary David. "X chromosome inactivation in mouse embryonal carcinoma cells". Thesis, University of Ottawa (Canada), 1985. http://hdl.handle.net/10393/4629.
Pełny tekst źródłaMetello, de Napoles Mariana. "Epigenetic modifications during X-chromosome inactivation and reactivation". Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422058.
Pełny tekst źródłaAger, Miranda. "Mechanisms of X chromosome inactivation : a transgenic approach". Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342240.
Pełny tekst źródła林德深 i Tak-sum Lam. "A biochemical study of mammalian x chromosome inactivation". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31981306.
Pełny tekst źródłaDossin, François. "Mechanistic dissection of SPEN functionduring X chromosome inactivation". Thesis, Université Paris sciences et lettres, 2021. http://www.theses.fr/2021UPSLS042.
Pełny tekst źródłaIn female placental mammals, dosage compensation of X-linked gene expression is achieved early during development through transcriptional inactivation of one of the two X chromosomes (XCI). This process is dependent on Xist, a long non-coding RNA which coats and silences the X chromosome from which it is transcribed. The mechanisms through which Xist initiates transcriptional silencing during XCI remain however completely unknown. In 2015, several studies identified that the SPEN protein binds Xist RNA directly, and its implication in mediating gene silencing was reported. However, its precise function and mechanism(s) of action during XCI are unclear.During my PhD, I made use of a conditional loss of function approach, the auxin inducible degron, to acutely deplete SPEN in mouse embryonic stem cells (mESCs) undergoing XCI. Using this approach, I demonstrate that SPEN is absolutely necessary for chromosome-wide Xist-mediated gene silencing during initiation of XCI. Furthermore, using conditional Spen KO mouse embryos, I show that SPEN is also required for the transcriptional inactivation of the paternal X chromosome during imprinted X inactivation. Depleting SPEN in differentiated cells, in which XCI has been established, reveals that SPEN is neither required to maintain gene silencing nor to preserve the spatial organization of the inactive X chromosome.By combining fixed and live cell imaging of Xist and SPEN, I show that SPEN colocalizes with Xist RNA, and accumulates on the X chromosome, immediately upon Xist upregulation, suggesting that SPEN can initiate gene silencing very early on during XCI. Profiling SPEN chromatin binding sites reveals that SPEN is recruited to promoters and enhancers of active genes specifically. The magnitude of SPEN recruitment to X-linked promoters dictates the efficiency with which these genes will be silenced. Remarkably, SPEN disengages from chromatin after gene silencing, indicating that active transcription required for SPEN’s association with chromatin.Using a functional complementation approach, I identify the SPOC domain as the effector of SPEN’s gene silencing activity during XCI. Artificial tethering of SPOC to Xist RNA results in transcriptional repression along the entire X chromosome, demonstrating that SPOC contains all the sufficient potential to instruct gene silencing during XCI. I further characterize the protein interactors of SPOC using mass spectrometry and reveal that SPOC interacts with several protein complexes involved in repressing transcription, including the NCoR/SMRT (histone deacetylation), the NuRD (nucleosome remodeling/histone deacetylation) and the m6A writing (governing mRNA fate) complexes. Finally, several transcription initiation and elongation factors are found to interact with SPOC, as well as the RNA polymerase II (RNAPII) transcription machinery.I identify that SPOC interacts directly and specifically with the C-terminal domain (CTD) of RNAPII only when the latter is phosphorylated on Ser5, and determine the 3D structure of the SPOC/RNAPII-CTD Ser5-P complex at 1.8Å resolution. These results suggest that SPEN could directly repress transcription during XCI by interfering with RNAPII-CTD Ser5-P templated processes.Altogether, my PhD work reveals that SPEN is essential for chromosome-wide transcriptional silencing during XCI, both in mESCs and in vivo. Following Xist upregulation, SPEN is immediately recruited to active gene promoters and enhancers, silences transcription, and subsequently disengages from chromatin. Through its RRMs and SPOC domains, SPEN acts as a molecular integrator, bridging Xist with histone deacetylases, nucleosome remodelers, RNA methyltransferases and most importantly, the transcription machinery
Lam, Tak-sum. "A biochemical study of mammalian x chromosome inactivation". [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12827186.
Pełny tekst źródłaForrester, Lesley Margaret. "Murine haematopoiesis : studies using X chromosome-inactivation mosaics". Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/28042.
Pełny tekst źródłaSprong, Amy Nicole. "X Chromosome Aneuploidy: A Look at the Effects of X Inactivation". Miami University Honors Theses / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1209079846.
Pełny tekst źródłaKsiążki na temat "X-chromosome inactivation"
Sado, Takashi, red. X-Chromosome Inactivation. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8766-5.
Pełny tekst źródłaSpotswood, Hugh Timothy. Histone modification and the epigenetics of X chromosome inactivation. Birmingham: University of Birminghm, 2002.
Znajdź pełny tekst źródłaMichalickova, Katerina. X-chromosome inactivation in females with deletions at Xq27-q28. Ottawa: National Library of Canada, 1996.
Znajdź pełny tekst źródłaFemales are mosaics: X inactivation and sex differences in disease. New York, NY: Oxford University Press, 2006.
Znajdź pełny tekst źródłaSado, Takashi. X-Chromosome Inactivation: Methods and Protocols. Springer New York, 2018.
Znajdź pełny tekst źródłaSado, Takashi. X-Chromosome Inactivation: Methods and Protocols. Springer New York, 2019.
Znajdź pełny tekst źródłaBrown, Carolyn Janet *. Studies of human X chromosome inactivation. 1991.
Znajdź pełny tekst źródłaMigeon, Barbara. Females Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, 2007.
Znajdź pełny tekst źródłaMigeon, Barbara. Females Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, USA, 2007.
Znajdź pełny tekst źródłaFemales Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, Incorporated, 2013.
Znajdź pełny tekst źródłaCzęści książek na temat "X-chromosome inactivation"
Gartler, S. M. "X Chromosome Inactivation". W Human Genetics, 192–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71635-5_22.
Pełny tekst źródłaLee, Jeannie T. "X-Chromosome Inactivation". W Development, 407–19. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59828-9_25.
Pełny tekst źródłaRobinson, Wendy P., Allison M. Cotton, Maria S. Peñaherrera, Samantha B. Peeters i Carolyn J. Brown. "X-Chromosome Inactivation". W Epigenetics and Complex Traits, 63–88. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8078-5_3.
Pełny tekst źródłaBrahmachari, Vani, i Shruti Jain. "X Chromosome Inactivation". W Encyclopedia of Systems Biology, 2363. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_859.
Pełny tekst źródłaAdams, Roger L. P., i Roy H. Burdon. "X-Chromosome Inactivation". W Molecular Biology of DNA Methylation, 163–69. New York, NY: Springer New York, 1985. http://dx.doi.org/10.1007/978-1-4612-5130-9_9.
Pełny tekst źródłaJaenisch, Rudolf, Caroline Beard, Jeannie Lee, York Marahrens i Barbara Panning. "Mammalian X Chromosome Inactivation". W Novartis Foundation Symposia, 200–213. Chichester, UK: John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470515501.ch12.
Pełny tekst źródłaLyon, Mary F. "Imprinting and X-Chromosome Inactivation". W Results and Problems in Cell Differentiation, 73–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-540-69111-2_4.
Pełny tekst źródłaSchorderet, Daniel F., i Stanley M. Gartler. "Steroid Sulphatase Inactivation Patterns and X-chromosome Inactivation". W Trends in Chromosome Research, 110–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-662-10621-1_8.
Pełny tekst źródłaMa, Wenxiu, Giancarlo Bonora, Joel B. Berletch, Xinxian Deng, William S. Noble i Christine M. Disteche. "X-Chromosome Inactivation and Escape from X Inactivation in Mouse". W Methods in Molecular Biology, 205–19. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8766-5_15.
Pełny tekst źródłaSinger-Sam, Judith, i Arthur D. Riggs. "X chromosome inactivation and DNA methylation". W DNA Methylation, 358–84. Basel: Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-9118-9_16.
Pełny tekst źródłaStreszczenia konferencji na temat "X-chromosome inactivation"
"X-chromosome Inactivation in American Mink iPSCs". W Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-310.
Pełny tekst źródłaSong, Yilin, Bryan M. McCauley, Melissa C. Larson, Sebastian M. Armasu, Kate Lawrenson, Ellen L. Goode, Nicholas B. Larson i Stacey J. Winham. "Abstract 2452: Evidence of decreased X chromosome inactivation in primary ovarian tumors". W Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2452.
Pełny tekst źródłaCastellini-Pérez, Olivia, Elena Povedano-Espejo, Guillermo Barturen, Abir Azri, Ruth Dominguez, Marta E. Alarcón-Riquelme i Elena Carnero-Montoro. "O5 Exploring the impact of genome-wide DNA methylation alterations on chromosome X inactivation and female lupus". W 14th European Lupus Meeting, Bruges, Belgium, March 19–22, 2024. Lupus Foundation of America, 2024. http://dx.doi.org/10.1136/lupus-2024-el.15.
Pełny tekst źródłaIbeawuchi, Helen, Nicole Werner i Les Keniston. "Role of X chromosome Inactivation Escapees andATMGene in Breast Neoplasia Severity and Survival". W ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.405.944050.
Pełny tekst źródłaWinham, Stacey J., Nicholas B. Larson, Sebastian M. Armasu, Zachary C. Fogarty, Melissa C. Larson, Kimberly R. Kalli, Kate Lawrenson, Simon Gayther, Brooke L. Fridley i Ellen L. Goode. "Abstract 2420: Integrative analyses of gene expression, DNA methylation, genotype and copy number alterations characterize X-chromosome inactivation in ovarian cancer". W Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2420.
Pełny tekst źródłaManié, E., T. Popova, A. Vincent-Salomon, T. Dubois, O. Delattre, X. Sastre-Garau, D. Stoppa-Lyonnet i M.-H. Stern. "P3-06-03: Hypodiploidy, 1pter Loss and Inactive X Chromosome Retention Are Associated with BRCA1 Somatic or Germline Inactivation in Basal-Like Breast Carcinomas: Proposal for a New BRCAness Genomic Signature." W Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p3-06-03.
Pełny tekst źródłaRaporty organizacyjne na temat "X-chromosome inactivation"
Panning, Barbara. X Chromosome Inactivation and Breast Cancer: Epigenetic Alteration in Tumor Initiation and Progression. Fort Belvoir, VA: Defense Technical Information Center, wrzesień 2007. http://dx.doi.org/10.21236/ada474949.
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