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Gotowa bibliografia na temat „Whirlin”

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Data publikacji: 25 maja 2024

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Artykuły w czasopismach na temat "Whirlin"

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Zou, Junhuang, Ling Luo, Zuolian Shen, Vince A. Chiodo, Balamurali K. Ambati, William W. Hauswirth i Jun Yang. "Whirlin Replacement Restores the Formation of the USH2 Protein Complex in Whirlin Knockout Photoreceptors". Investigative Opthalmology & Visual Science 52, nr 5 (12.04.2011): 2343. http://dx.doi.org/10.1167/iovs.10-6141.

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Hurtley, S. M. "CELL BIOLOGY: Whirlin to the Tip". Science 307, nr 5709 (28.01.2005): 485c. http://dx.doi.org/10.1126/science.307.5709.485c.

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Ciardo, Maria Grazia, Amparo Andrés-Bordería, Natalia Cuesta, Pierluigi Valente, María Camprubí-Robles, Jun Yang, Rosa Planells-Cases i Antonio Ferrer-Montiel. "Whirlin increases TRPV1 channel expression and cellular stability". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863, nr 1 (styczeń 2016): 115–27. http://dx.doi.org/10.1016/j.bbamcr.2015.10.016.

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Oetke, Svenja, Axel J. Scheidig i Karin Krupinska. "WHIRLY1 of Barley and Maize Share a PRAPP Motif Conferring Nucleoid Compaction". Plant and Cell Physiology 63, nr 2 (11.11.2021): 234–47. http://dx.doi.org/10.1093/pcp/pcab164.

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Abstract WHIRLY1 in barley was shown to be a major architect of plastid nucleoids. Its accumulation in cells of Escherichia coli coincided with an induction of nucleoid compaction and growth retardation. While WHIRLY1 of maize had similar effects on E. coli cells, WHIRLY1 proteins of Arabidopsis and potato as well as WHIRLY2 proteins had no impact on nucleoid compaction in E. coli. By mutagenesis of HvWHIRLY1 the PRAPP motif at the N-terminus preceding the highly conserved WHIRLY domain was identified to be responsible for the nucleoid compacting activity of HvWHIRLY1 in bacteria. This motif is found in WHIRLY1 proteins of most members of the Poaceae family, but neither in the WHIRLY2 proteins of the family nor in any WHIRLY protein of eudicot species such as Arabidopsis thaliana. This finding indicates that a subset of the monocot WHIRLY1 proteins has acquired a specific function as nucleoid compacters by sequence variation in the N-terminal part preceding the conserved WHIRLY domain and that in different groups of higher plants the compaction of nucleoids is mediated by other proteins.
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Prosser, Haydn M., Agnieszka K. Rzadzinska, Karen P. Steel i Allan Bradley. "Mosaic Complementation Demonstrates a Regulatory Role for Myosin VIIa in Actin Dynamics of Stereocilia". Molecular and Cellular Biology 28, nr 5 (26.12.2007): 1702–12. http://dx.doi.org/10.1128/mcb.01282-07.

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ABSTRACT We have developed a bacterial artificial chromosome transgenesis approach that allowed the expression of myosin VIIa from the mouse X chromosome. We demonstrated the complementation of the Myo7a null mutant phenotype producing a fine mosaic of two types of sensory hair cells within inner ear epithelia of hemizygous transgenic females due to X inactivation. Direct comparisons between neighboring auditory hair cells that were different only with respect to myosin VIIa expression revealed that mutant stereocilia are significantly longer than those of their complemented counterparts. Myosin VIIa-deficient hair cells showed an abnormally persistent tip localization of whirlin, a protein directly linked to elongation of stereocilia, in stereocilia. Furthermore, myosin VIIa localized at the tips of all abnormally short stereocilia of mice deficient for either myosin XVa or whirlin. Our results strongly suggest that myosin VIIa regulates the establishment of a setpoint for stereocilium heights, and this novel role may influence their normal staircase-like arrangement within a bundle.
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Lin, Bisen, i K. Ravi-Chandar. "An Experimental Investigation of the Motion of Flexible Strings: Whirling". Journal of Applied Mechanics 73, nr 5 (13.12.2005): 842–51. http://dx.doi.org/10.1115/1.2172270.

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Whirling of strings has been studied both theoretically and experimentally for many decades. According to linear theory, a heavy string can exhibit steady-state whirl only at its natural frequencies which form a discrete spectrum. The nonlinear theory, however, suggests that a string can undergo steady whirl at any frequency larger than the fundamental frequency and further that for each frequency between the nth and the (n+1)th eigenvalue, there exist n distinct whirling modes. Quantitative experimental observations on such whirling have never been reported, although anecdotal evidence suggests the possibility of such whirl. In this paper, we examine the whirling of a string with negligible bending stiffness through experiments utilizing a stereo-vision imaging system. It is shown that steady motion exists only when the string whirls at its natural frequencies and that whirling motions for other frequencies exhibit rich dynamics that needs further exploration.
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Mogensen, Mette M., Agnieszka Rzadzinska i Karen P. Steel. "The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development". Cell Motility and the Cytoskeleton 64, nr 7 (2007): 496–508. http://dx.doi.org/10.1002/cm.20199.

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Delhommel, Florent, Florence Cordier, Frederick Saul, Lucas Chataigner, Ahmed Haouz i Nicolas Wolff. "Structural plasticity of the HHD 2 domain of whirlin". FEBS Journal 285, nr 20 (5.09.2018): 3738–52. http://dx.doi.org/10.1111/febs.14614.

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Gautier, Candice, Francesca Troilo, Florence Cordier, Francesca Malagrinò, Angelo Toto, Lorenzo Visconti, Yanlei Zhu, Maurizio Brunori, Nicolas Wolff i Stefano Gianni. "Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate". Proceedings of the National Academy of Sciences 117, nr 33 (3.08.2020): 19963–69. http://dx.doi.org/10.1073/pnas.2004138117.

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Although more than 75% of the proteome is composed of multidomain proteins, current knowledge of protein folding is based primarily on studies of isolated domains. In this work, we describe the folding mechanism of a multidomain tandem construct comprising two distinct covalently bound PDZ domains belonging to a protein called Whirlin, a scaffolding protein of the hearing apparatus. In particular, via a synergy between NMR and kinetic experiments, we demonstrate the presence of a misfolded intermediate that competes with productive folding. In agreement with the view that tandem domain swapping is a potential source of transient misfolding, we demonstrate that such a kinetic trap retains native-like functional activity, as shown by the preserved ability to bind its physiological ligand. Thus, despite the general knowledge that protein misfolding is intimately associated with dysfunction and diseases, we provide a direct example of a functionally competent misfolded state. Remarkably, a bioinformatics analysis of the amino acidic sequence of Whirlin from different species suggests that the tendency to perform tandem domain swapping between PDZ1 and PDZ2 is highly conserved, as demonstrated by their unexpectedly high sequence identity. On the basis of these observations, we discuss on a possible physiological role of such misfolded intermediate.
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Lin, Lin, Yingdong Shi, Mengli Wang, Chao Wang, Qing Lu, Jinwei Zhu i Rongguang Zhang. "Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex". Cell Reports 34, nr 8 (luty 2021): 108770. http://dx.doi.org/10.1016/j.celrep.2021.108770.

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Rozprawy doktorskie na temat "Whirlin"

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Zhu, Yanlei. "The structural and functional role of whirlin in inner ear hair cells during development". Electronic Thesis or Diss., Sorbonne université, 2020. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2020SORUS358.pdf.

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Le syndrome d'Usher est l'un des syndromes neurosensoriels génétiques les plus courants, affectant à la fois la vision et l'audition. A ce jour, neuf gènes portant des mutations sont liés à ce syndrome. Mon projet de thèse porte sur la protéine Usher appelée Whirline, une protéine à domaine PDZ cruciale dans les systèmes auditifs et visuels. Nous avons caractérisé la fonction du troisième domaine PDZ, exposé à l'extrémité C-terminale de la protéine. Le PDZ3 reconnaît au moins sept protéines portant des motifs PBM (PDZ Binding Motif): CASK, MPP1, Myosine 15a, Protocadhérine 15 CD3, Cadhérine 23, Harmonine a1 et Taperine. Nous avons résolu les structures à haute résolution de quatre d'entre elles et mis en évidence la capacité de liaison très variée du PDZ3 de la Whirline à divers partenaires des cellules ciliées cochléaires. Du côté N-terminal de la Whirline, le premier domaine PDZ1 reconnait à la fois des motifs peptidiques et des lipides. Nous avons caractérisé en détail ce PDZ1, isolé et inclus dans des constructions multi-domaines, en interaction avec des protéines et des membranes lipidiques par diverses approches biophysiques. La structure de PDZ1 en complexe avec des PBM partenaires et avec des lipides a été résolu, mettant en évidence les résidus impliqués dans de telles interactions. De plus, nous avons documenté le rôle du domaine HHD1 situé juste en amont du domaine PDZ1 et impliqué dans l'auto-association de la Whirline. L’ensemble de ces propriétés de la Whirline est lié à sa fonction de protéine d'échafaudage qui assure l'ancrage des protéines membranaires Usher, un réseau de protéines sous-membranaires essentielles au développement des cellules ciliées
Usher syndrome is one of the most common genetic neurosensory syndromes, which affects both vision and hearing. So far, nine genes’ mutations have been found related to the Usher syndrome. My PhD project focuses on one Usher protein Whirlin, a PDZ containing multi-domain scaffolding protein. We characterised the function of the third PDZ domain which is fully exposed at the C-terminus of the protein. PDZ3 recognizes at least seven proteins PBM (PDZ Binding Motif): CASK, MPP1, Myosin 15a, Protocadherin 15 CD3, Cadherin 23, Harmonin a1 and Taperin, and we solved the high-resolution structures of four of them. We highlighted the unexpected binding capacity of the Whirlin PDZ3. The first N-terminal PDZ1 is a domain of dual functions, which recognizes both protein PBM and lipids. We deeply characterised the PDZ1 in interaction with proteins and lipid membranes by various biophysical approaches. We solved the structures of PDZ1 in complex with partner PBM and with lipid, and highlighted the residues specifically involved in such interactions. In addition, we emphasized the role of the upstream N-terminal HHD1 domain adjacent to the PDZ1 domain and involved in the self-association of Whirlin. Altogether, these properties of Whirlin are related to its function as a scaffolding protein that ensures the anchoring of the membrane Usher proteins, a submembrane protein network essential for the development of hair bundle and for the photoreceptor functioning
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Delhommel, Florent. "Etude structurale de la Whirline, protéine modulaire cruciale dans les mécanismes de la vision et de l'audition". Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066151/document.

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La vue et l'ouïe font intervenir des cellules capables de rapidement traduire une onde, lumineuse ou sonore, en un message électrochimique transmissible au cerveau. La fonction de ces cellules sensitives repose sur leurs morphologies uniques. Les mutations de onze gènes sont la cause des syndromes Usher, associant cécité et surdité. Les protéines Usher sont indispensables à l'architecture de ces deux types cellulaires ; elles forment des complexes dont les interactions clés sont maintenues principalement par des domaines PDZ. L'une des protéines centrales de ce réseau est la Whirline, une protéine multi-domaine contenant trois domaines PDZ. Pour comprendre les bases moléculaires des syndromes Usher, nous nous sommes concentrés sur la caractérisation biochimique et biophysique de la Whirline. Nous avons identifié un nouveau domaine HHD2 de la Whirline dont nous avons obtenue la structure à haute résolution et déterminé le comportement en solution, isolé et avec les domaines adjacents. Nous avons ensuite caractérisé un supramodule transitoire entre deux domaines PDZ, maintenu par des extensions structurées de chacun des domaines. Nous avons résolu la structure de la conformation compacte unique de ce complexe et étudié son équilibre avec un ensemble de conformations étendues. Nous avons enfin caractérisé in vitro le réseau d'interaction des domaines PDZ de la Whirline avec les protéines Usher. L'ensemble de nos résultats sur la structure modulaire et l'interactome de la Whirline permet de mieux comprendre le rôle de la Whirline dans les différents complexes Usher et d'expliquer les conséquences de ses mutations sur les mécanismes moléculaires de l'audition et de la vision
Vision and hearing rely on the capacity of cells to rapidly transduce electromagnetic waves or sound waves into chemical messages that are transmissible to the brain. The function of these sensory cells requires unique morphologies. The mutations of eleven genes are responsible for Usher syndromes, associating blindness and deafness. The Usher proteins are pivotal to the architecture of the photoreceptor and hearing cells. They form complexes in which the critical interactions are mainly maintained by PDZ domains. One of these central proteins is Whirlin, a multi-domain protein encompassing three PDZ domains. To understand the molecular basis of the Usher syndromes, we focused our project on the biochemical and biophysical characterization of Whirlin. We identified a new HHD2 domain on Whirlin, for which we solved the structure at high resolution and determined the behavior in solution, isolated or with adjacent domains. We then identified a transient supramodule between two PDZ domains, maintained by PDZ structured extensions. We determined the structure of the compact and unique conformation of this tandem and we characterized its equilibrium with an ensemble of more extended conformations. Finally, we characterized in vitro the network of interaction of the PDZ domains of Whirlin, with the majority of the Usher proteins. Our results on the modular structure and the interactome of Whirlin get insight into the role of Whirlin in the numerous complexes formed by the Usher proteins and allow to better explain the consequences of its mutation on the molecular mechanisms of hearing and vision
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Delhommel, Florent. "Etude structurale de la Whirline, protéine modulaire cruciale dans les mécanismes de la vision et de l'audition". Electronic Thesis or Diss., Paris 6, 2017. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2017PA066151.pdf.

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La vue et l'ouïe font intervenir des cellules capables de rapidement traduire une onde, lumineuse ou sonore, en un message électrochimique transmissible au cerveau. La fonction de ces cellules sensitives repose sur leurs morphologies uniques. Les mutations de onze gènes sont la cause des syndromes Usher, associant cécité et surdité. Les protéines Usher sont indispensables à l'architecture de ces deux types cellulaires ; elles forment des complexes dont les interactions clés sont maintenues principalement par des domaines PDZ. L'une des protéines centrales de ce réseau est la Whirline, une protéine multi-domaine contenant trois domaines PDZ. Pour comprendre les bases moléculaires des syndromes Usher, nous nous sommes concentrés sur la caractérisation biochimique et biophysique de la Whirline. Nous avons identifié un nouveau domaine HHD2 de la Whirline dont nous avons obtenue la structure à haute résolution et déterminé le comportement en solution, isolé et avec les domaines adjacents. Nous avons ensuite caractérisé un supramodule transitoire entre deux domaines PDZ, maintenu par des extensions structurées de chacun des domaines. Nous avons résolu la structure de la conformation compacte unique de ce complexe et étudié son équilibre avec un ensemble de conformations étendues. Nous avons enfin caractérisé in vitro le réseau d'interaction des domaines PDZ de la Whirline avec les protéines Usher. L'ensemble de nos résultats sur la structure modulaire et l'interactome de la Whirline permet de mieux comprendre le rôle de la Whirline dans les différents complexes Usher et d'expliquer les conséquences de ses mutations sur les mécanismes moléculaires de l'audition et de la vision
Vision and hearing rely on the capacity of cells to rapidly transduce electromagnetic waves or sound waves into chemical messages that are transmissible to the brain. The function of these sensory cells requires unique morphologies. The mutations of eleven genes are responsible for Usher syndromes, associating blindness and deafness. The Usher proteins are pivotal to the architecture of the photoreceptor and hearing cells. They form complexes in which the critical interactions are mainly maintained by PDZ domains. One of these central proteins is Whirlin, a multi-domain protein encompassing three PDZ domains. To understand the molecular basis of the Usher syndromes, we focused our project on the biochemical and biophysical characterization of Whirlin. We identified a new HHD2 domain on Whirlin, for which we solved the structure at high resolution and determined the behavior in solution, isolated or with adjacent domains. We then identified a transient supramodule between two PDZ domains, maintained by PDZ structured extensions. We determined the structure of the compact and unique conformation of this tandem and we characterized its equilibrium with an ensemble of more extended conformations. Finally, we characterized in vitro the network of interaction of the PDZ domains of Whirlin, with the majority of the Usher proteins. Our results on the modular structure and the interactome of Whirlin get insight into the role of Whirlin in the numerous complexes formed by the Usher proteins and allow to better explain the consequences of its mutation on the molecular mechanisms of hearing and vision
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Gates, Kiza Kristine. "Myxospore detection in soil and angler movement in Southwestern Montana implications for whirling disease transport /". Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/gates/GatesK0507.pdf.

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KHATOON, RABEYA. "Whirling Hybrids: A Dichotomy Of Belonging". VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5892.

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Migration is a phenomenon wherein individuals relocate from one country to another, albeit temporarily or permanently, for numerous reasons. The State of Qatar is a highly diverse nation with a large population of foreign residents. According to Priya D’Souza, as of 2017, 60 percent of the resident population in Qatar are from South Asia. Growing up in this environment, third culture kids develop a unique, hybrid culture through experiencing multiple cultures. This research investigates a dichotomy of belonging from the perspective of South Asians in Qatar. A series of hybridized spinning tops were produced in collaboration with a South Asian artisan. These hybridized artifacts are infused with sensory materials in order to elicit an emotive response, engage memory, and celebrate the merging of diverse cultures.
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Hamilton, Andrew John. "The aetiology of whirling disease, Myxosoma cerebralis". Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/38344.

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Marsden, James Anthony. "Experimental and numerical studies of whirling fires". Thesis, University of Central Lancashire, 2005. http://clok.uclan.ac.uk/8689/.

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Motivation of this study stems from the need to understand the physical mechanisms of whirling fires that occur in an open space and within enclosures. Buoyant whirling flames may be potentially more destructive than ordinary fires due to greater burning rate, higher concentration of heat release in a small region of the plume core, increased radiative output and unexpected smoke movement. The effects of rotation upon the structure and behaviour of buoyant flames have not yet been thoroughly studied and understood. Investigation of this phenomenon is therefore required to allow techniques to be developed that will counter the threat of such outbreaks. Also, the mechanisms controlling the development and stability of whirling flames are of fundamental interest for refined modelling of coherent and self-organised flame behaviour. This work, is an experimental, theoretical and numerical study of whirling fires. Experimental results, a modified CFD model and simulations of whirling flames are presented within this Thesis. The work aims to overcome the limitations of the previous research of whirling fires which is insufficient from both an experimental and theoretical point of view. Firstly, experimental studies of intermediate (room-size) scale whirling fires have not yet been comprehensively reported, despite a great deal of attention devoted to both large scale mass fires and smaller laboratory flames. Experimental studies undertaken using a facility at the Greater Manchester Fire and Rescue Service Training Centre fill this gap, thus demonstrating that whirling flames may develop within a compartment. The periodic precession, formation and destruction of the whirling flame and the increase of the time-averaged burning rate (compared to non-whirling flames in the open space) have been observed. Three fuels with significantly different burning rates (diesel, heptane and ethanol) were investigated in this work. Secondly, previously published results of theoretical analysis of rotating flames were oversimplified and based on strict limitations of the integral model or the inviscid flow assumption. Also there have only been few attempts to undertake CFD modelling of whirling flames. In published studies, radiative heat transfer was not modelled and the burning rate was not coupled with the incident heat flux at the fuel surface. To overcome these limitations, the CFD fire model Fire3D, developed in the Centre for Research in Fire and Explosion Studies, has been adapted to allow numerical simulations of rotating buoyant turbulent diffusion flames. The turbulence model was modified to take into account stabilisation of turbulent fluctuations due to the centrifugal acceleration within the rotating flow. Theoretical analysis of the vorticity equation revealed the physical mechanisms responsible for vorticity concentration and amplification in the rising plume affected by externally imposed circulation. This explains the significant flame elongation (when compared to non-rotating cases) observed in the experiments. Computational results have also been compared to video-recordings of the experimental flames produced; flame elongation was replicated and similar stages of oscillating flame evolution, including formation and destruction of the vortex core, have been identified. Implications of the phenomena studied in relation to fire engineering are also provided. This study contributes to a performance based framework for an engineering approach, which is reliant upon detailed quantitative analysis and modelling. Such an approach is encouraged by modem fire safety legislation including the guides to fire safety engineering BS9999-21 and BS79742 'British Standard 9999-2 Draft Code of Practice for fire safety in the design, construction and use of buildings. BSI, 2004. UK. 2 British Standard BS7974 Application of fire safety engineering principles to the design of buildings. BSI, 2001-2003. UK.
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Suryanarayanan, Arun. "Experimental measurement and analysis of wall pressure distribution for a 50% eccentric whirling annular seal". Texas A&M University, 2003. http://hdl.handle.net/1969.1/1205.

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In any rotating machinery, the geometry of the seal influences the extent of systemleakage. The path taken by the flow in the clearance volume is dependent on the seal and rotor profile. The clearance between a new "seal-rotor" combination is uniform except for small variations during manufacturing and assembly. With time this annular cross section undergoes further physical changes causing non-uniform flow in the annular volume. This azimuthally varying leakage through the seal-rotor annulus creates unbalanced forces on the rotor causing it to whirl. It is essential to identify the reasons for these unwanted forces. Velocity profiling of the clearance volume flow was performed by Morrison et al. (1992) using 3-D LDA measurements on annular and labyrinth seals operating with 50% dynamic eccentricities and a whirl ratio of one. However, this alone does not provide a complete matrix of data for the conditions prevailing in the clearance zone. Additional information of mean and instantaneous wall pressure distributions for 0%, 10%, 25% and 50% rotor dynamic eccentricity for whirl ratios of zero and one, with positive pre-swirl, no pre-swirl and negative pre-swirl conditions were measured by Robic (1999). The data collected showed that the pressure field on the seal walls reversed itself between the whirling and non-whirling conditions. As a continuance of the earlier works, the present effort investigates the effect of whirl ratio variation for a 50% eccentric smooth annular seal at a leakage Reynolds number of 24000. An attempt has been made to collect pressure data for negative whirl ratios also under similar test conditions. A seal test rig capable of handling different eccentricities and whirl ratios simultaneously was designed and constructed for this purpose. Mean and instantaneous wall pressure data were recorded for 50% eccentricity with whirl ratios between ? 1 for a rotor speed of 1800. For a rotor speed of 2700, whirl ratios tested were between ? 0.6 and for 3600 rotor speed, whirl ratios ranging between ? 0.5 were tested. From the collected data a detailed analysis of wall pressures along the seal surface is performed following the technique described by Winslow (1994) and Robic (1999).
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Shum, Wai Sun. "Vibration frequencies of whirling rods and rotating annuli". Thesis, Curtin University, 2005. http://hdl.handle.net/20.500.11937/1404.

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Static Whirling Rods: Past researchers suggested that “static instabilities” exist at certain rotational speeds of whirling rods. This thesis shows these instabilities are an artefact of the material constitutive laws that are being used well outside their range of applicability. An alternative approach is developed where strains due to rotation are separated from the superimposed vibration. This enables the generally predicted lowering of longitudinal natural frequencies with rotational speed shown to be simply a result of the bulk changes in the geometry of whirling rods. Steady state equations of whirling rods are formulated in Lagrangian coordinates. Due to the non-linear nature of the governing equations, an original numerical method is applied to solve the problem. Numerical results are compared with analytical results obtained from the linearized uniaxial model. There is a close agreement between these two models at low angular velocities. However, at high angular velocities, discrepancies between them arise, confirming that the nonlinear strain-displacement relationship has significant effect on the results and the inferred “static instabilities”. This approach first solves the “static” problem of the deformed geometry of a highly strained whirling rod before longitudinal natural modes are determined by classical methods. Furthermore, conditions for existence and uniqueness of solutions are derived. Dynamic Rotating Annuli: In-plane modes of vibration of annular plates are investigated. Two different models of equations one from Bhuta and Jones and the other from Biezeno and Grammel that govern the rotational motions of annuli will be studied. Since Biezeno and Grammel’s model was originally derived in Eulrian coordinates, their model will be transformed to the Lagrangian coordinates for the purpose of comparison with Bhuta and Jones’ model.The solutions of the equations assume small oscillations of vibration being superimposed on the steady state of the annulus while it is in rotation. Exact and approximate solutions are obtained for the Bhuta and Jones’ model, where the approximate solutions on in-plane displacements and natural frequencies are acquired by ignoring the Coriolis effect. A proposed numerical scheme is implemented to solve the governing equations coupled with radial and circumferential displacements. Uniqueness of solutions will be mentioned although it will not be rigorously derived because it is out of the scope of this thesis. Approximate analytical results show that both radial and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing. The exact and numerical results on both models that take the Coriolis effect into account show that radial natural frequencies are increasing and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing.
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Shum, Wai Sun. "Vibration frequencies of whirling rods and rotating annuli". Curtin University of Technology, Faculty of Engineering and Computing, 2005. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=16363.

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Static Whirling Rods: Past researchers suggested that “static instabilities” exist at certain rotational speeds of whirling rods. This thesis shows these instabilities are an artefact of the material constitutive laws that are being used well outside their range of applicability. An alternative approach is developed where strains due to rotation are separated from the superimposed vibration. This enables the generally predicted lowering of longitudinal natural frequencies with rotational speed shown to be simply a result of the bulk changes in the geometry of whirling rods. Steady state equations of whirling rods are formulated in Lagrangian coordinates. Due to the non-linear nature of the governing equations, an original numerical method is applied to solve the problem. Numerical results are compared with analytical results obtained from the linearized uniaxial model. There is a close agreement between these two models at low angular velocities. However, at high angular velocities, discrepancies between them arise, confirming that the nonlinear strain-displacement relationship has significant effect on the results and the inferred “static instabilities”. This approach first solves the “static” problem of the deformed geometry of a highly strained whirling rod before longitudinal natural modes are determined by classical methods. Furthermore, conditions for existence and uniqueness of solutions are derived. Dynamic Rotating Annuli: In-plane modes of vibration of annular plates are investigated. Two different models of equations one from Bhuta and Jones and the other from Biezeno and Grammel that govern the rotational motions of annuli will be studied. Since Biezeno and Grammel’s model was originally derived in Eulrian coordinates, their model will be transformed to the Lagrangian coordinates for the purpose of comparison with Bhuta and Jones’ model.
The solutions of the equations assume small oscillations of vibration being superimposed on the steady state of the annulus while it is in rotation. Exact and approximate solutions are obtained for the Bhuta and Jones’ model, where the approximate solutions on in-plane displacements and natural frequencies are acquired by ignoring the Coriolis effect. A proposed numerical scheme is implemented to solve the governing equations coupled with radial and circumferential displacements. Uniqueness of solutions will be mentioned although it will not be rigorously derived because it is out of the scope of this thesis. Approximate analytical results show that both radial and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing. The exact and numerical results on both models that take the Coriolis effect into account show that radial natural frequencies are increasing and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing.
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Książki na temat "Whirlin"

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Wallace-Crabbe, Chris. Whirling. New York: Oxford University Press, 1998.

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Whirling. Oxford: Oxford University Press, 1998.

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Thomas, Jack Lyndon. Whirling fire. Houston, TX: lyndonjacks publications, 1997.

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Farooqi, Shafique. Whirling Dervish. Lahore: Hamail Art Galleries, 2005.

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Schisler, George J. Whirling disease investigations: Federal aid project F-237-R : job 5, rapid assessment technique evaluation. Fort Collins, Colo: Colorado Division of Wildlife, Fish Research Section, 2000.

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Schisler, George J. Whirling disease investigations: Federal aid project F-237-R. Fort Collins, Colo: Colorado Division of Wildlife, Fish Research Section, 2001.

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D. I. T. P. Llewelyn-Davies. The redesign of the College of Aeronautics whirling arm facility. Cranfield, England: College of Aeronautics, Cranfield Institute of Technology, 1987.

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Nehring, R. Barry. Whirling disease investigations. Fort Collins, Colo: Colorado Division of Wildlife, Fish Research Section, 2005.

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Nehring, R. Barry. Whirling disease investigations. Fort Collins, Colo: Colorado Division of Wildlife, Fish Research Section, 2007.

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Nehring, R. Barry. Whirling disease investigations. Fort Collins, Colo: Colorado Division of Wildlife, Fish Research Section, 2008.

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Części książek na temat "Whirlin"

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Yudin, Andrey. "Whirlpool, Whirl, Swirl, and Whirling Sign". W Metaphorical Signs in Computed Tomography of Chest and Abdomen, 145. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04013-4_73.

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Yudin, Andrey. "Whirlpool or Whirl, Swirl, Whirling Sign". W Metaphorical Signs in Computed Tomography of Chest and Abdomen, 205. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-24494-0_103.

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Groves, James E. "“Wild and Whirling Words”". W Hamlet on the Couch, 89–102. London; New York: Routlege, 2017.: Routledge, 2017. http://dx.doi.org/10.4324/9781315150055-8.

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Çizmeci, Esra. "Whirling “Anytime and AnyPlace” *". W Performing Post-Tariqa Sufism, 97–124. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003118589-6.

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Cope, David. "The whirlwind". W Silences for Love, 107–19. Totowa, NJ: Humana Press, 1998. http://dx.doi.org/10.1007/978-1-4612-1812-8_9.

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Ketkar, Sachin. "Whirlwind (Vavtal)". W Vyankatesh Madgulkar, 67–69. London: Routledge India, 2023. http://dx.doi.org/10.4324/9781003159315-11.

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Ryder, G. H., i M. D. Bennett. "Lateral Vibrations and Whirling Speeds". W Mechanics of Machines, 294–309. London: Palgrave Macmillan UK, 1990. http://dx.doi.org/10.1007/978-1-349-21112-8_15.

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Seargent, David A. J. "Tornadoes and Other Whirling Winds". W Weird Weather, 215–58. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-3070-4_5.

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Crinall, Sarah. "Unraveling Water; Whirling Washing Machine". W Children: Global Posthumanist Perspectives and Materialist Theories, 37–82. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3007-0_2.

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Zhou, Kuibin. "Fire Whirls". W Encyclopedia of Wildfires and Wildland-Urban Interface (WUI) Fires, 1–9. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-51727-8_23-1.

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Streszczenia konferencji na temat "Whirlin"

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Satoh, Koyu, Naian Liu, Xiaodong Xie i Wei Gao. "CFD Study of a Fire Whirl of Huge Oil Tank: Burning Rate, Flame Length, Distributions of n-Heptane and Oxygen in a Fire Whirl". W ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-37276.

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The number of huge oil storage tanks is increasing in the world. If a fire occurs in one of these tanks, it is very difficult to suppress. Additionally, if a fire whirl occurs in an oil tank fire, it is extremely dangerous for firefighters to extinguish the fire. The authors have numerically studied huge fire whirls in a large oil tank depot and predicted the generation of those fire whirls. Here, another study is attempted to clarify the details of huge fire whirl in a large oil tank, using two kinds of fire whirl generation channels in CFD simulations using the software, FDS by NIST. Details of burning rates, velocities of whirling flames, radiative heat flux, heat release rates and whirling cycles are examined, using oil tanks with the diameters of 0.2 to 80 m. In oil tanks with a diameter of 80 m, a tall fire whirl is generated. The height is about 1000 m. In this study of oil tanks fires with small to large diameters, it has been found that fire whirl lengths are about 8 to 11 times of the oil tank diameter. The maximum radiative heat flux due to a fire whirl in 80 m diameter oil tanks exceeds 100 kW/m2. Since the maximum radiation is found at twice the distance of oil tank diameters from the tank centers, adjacent oil tanks may be ignited. This study has also examined a method used to prevent fire whirl generation in huge oil tanks.
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Huo, Yan, W. K. Chow i Ye Gao. "Internal Fire Whirls Induced by Pool Fire in a Vertical Shaft". W ASME/JSME 2011 8th Thermal Engineering Joint Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajtec2011-44477.

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Internal fire whirls induced by a pool fire in a square vertical shaft were studied by experiments and numerical simulations. The burning behaviour of two pool fires in the vertical shaft and in open air was compared. The gap width of the rig is a key factor in onsetting fire whirls. Air flow field in the vertical square shaft of different gap widths were studied experimentally with nine tests. A fire whirl would not be onsetted when the gap is too narrow nor too wide. Whirling flame is not clearly observed near to the bottom of the vertical shaft when the gap width was small.
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Farouk, B., K. B. McGrattan i R. G. Rehm. "Large Eddy Simulation of Naturally Induced Fire Whirls in a Vertical Square Channel With Corner Gaps". W ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1562.

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Abstract Naturally occurring fire whirls are rare but highly destructive phenomena. These are mostly generated by the interaction between a buoyant fire plume and its surroundings. The whirling motion generated can enhance the plume length and sustain burning. In this paper, we report the results of a numerical investigation of whirling fires generated in vertical square channels with symmetric corner gaps. The numerical investigations of swirling fire plumes are used to analyze how the corner gaps alters the plume dynamics and combustion. An approximate (low Mach number) form of the Navier-Stokes equations is solved to calculate the mixing and transport of combustion products. Large scale eddies are directly simulated and sub-grid scale motion is represented with a Smagorinsky model. The current approach is based on a fixed heat release rate, regardless of the strength of the whirl generated by the corner slots. The effect of corner slot widths and their configuration on the swirling motion are studied systematically for a given channel geometry and fixed fuel-loss rate.
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Satoh, Kohyu, i K. T. Yang. "Measurements of Fire Whirls From a Single Flame in a Vertical Square Channel With Symmetrical Corner Gaps". W ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-1116.

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Abstract One of the most destructive forces in large urban fires is the occurrence of fire whirls. Despite the relatively recent experimental and numerical simulation studies on the global behaviors of small-scale whirling fires, much of the whirling fire phenomena still remain unknown. The purpose of this experimental study is to examine closely the detailed structures of the velocity and temperature fields in a stable whirling flame generated in a vertical square channel with symmetrical corner gaps by both physical measurements using conventional means and by quantitative observations using both a high-speed motion camera and a thermographic infrared camera. The results showed a rather complex non-uniform velocity and temperature field in the lower half of the whirling flame and could provide an important basis to validate the fire field models for the study of real large-scale fire whirls.
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Satoh, Kohyu, Liu Naian, Masahiko Shinohara i K. T. Yang. "Large-Scale Laboratory Fire Whirls and Their Numerical Simulations". W ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/htd-24242.

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Abstract Fire whirls have been observed in large-scale forest and city fires, which are likely accompanied by strong winds and heavy damages such as loss of lives and physical properties. Despite the general interest in the research of fire whirls, their detailed mechanisms and physical effects still remain largely unknown. One reason is that such real fire whirls are of large size and their direct studies are obviously not feasible. On the other hand, CFD-based fire field models, despite their inherent deficiencies, do provide a rational means to scale the fire sizes. It is desirable, or even necessary, to study larger-scale fire whirls with higher whirling flames in the laboratory, along with their numerical simulations. If success in the numerical simulations for the larger fire whirls can again be demonstrated, we will then approach more closely to have a quantitative tool in the use of the fire field model to simulate and study the truly large real-life fire whirls. The purpose of the present study is to attempt to create a stable six-meter class whirling flame in the laboratory, and then compare the measured data with what can be simulated with a fire field model.
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Vlajic, Nicholas, Xianbo Liu, Hamad Karki i Balakumar Balachandran. "Rotor Torsion Vibrations in the Presence of Continuous Stator Contact". W ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-89195.

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The purpose of this study is to examine the torsion response of a rotor while in continuous contact with a stator for both forward synchronous whirling and backward dry-friction whirling. Experimentally obtained torsional strain data for both of these motions are presented, and the results indicate that the major contributions to the motions occur at the drive speed fd, twice the drive speed 2fd and the first torsional natural frequency ft for forward whirling. During backward whirling, the dominant response occurs at the drive speed fd and the sum of the whirl speed plus the drive speed at fw + fd. A distributed-parameter model in combination with a force-interaction model is used to capture the qualitative aspects of the system response. Simulations with this model reveal that the torsional vibrations are excited by stick-slip forces while undergoing backward whirling. Numerical and experimental results also show that motion at the first torsion natural frequency is the dominant component during forward whirling.
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Chang, Sunghwan, i Young-Ho Cho. "Static Chaos Microfluid Mixers Using Microblock-Induced Alternating Whirl and Microchannel-Induced Lamination". W ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-41230.

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We characterize two types of noble static chaos microfluid mixers for the applications to Micro Total Analysis Systems (μTAS): an AW-type microfluid mixer, having a series of microblocks along a flow channel for generating alternating direction whirl (AW) flows, and an AWL-type microfluid mixer, coupling the AW-type microfluid mixers with divided microchannels for generating lamination flows between the alternating whirl flows. For generating whirling flow in microchannels, we design rotating block geometry in microchannels. For chaos mixing, we suggest alternating-directional whirling flows in microchannels. AW, AWL-type microfluid mixers are made of PDMS (Polydimethylsiloxane). We quantify mixing state using phenolphthalein visualization experiments and measure pressure drop through microfluid mixers.
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Satoh, Koyu, Domingos Viegas, Claudia Pinto i Ran Tu. "CFD Study of Generation Process and Stability of a Fire Whirl in Large-Scale Fires". W ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10173.

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Abstract Large-scale urban and forest fires, especially earthquake-induced fires may produce huge fire whirls and cause serious damage, due to the involved tornado-like strong wind, together with radiation and swirling flame. If fire whirls are generated, the danger to firefighters increases extremely. Many small-scale experiments and CFD simulations on fire whirls have already been conducted and also our previous numerical studies examined the generation of a large fire whirl in an oil tank. However, details of large-scale fire whirls have not been clarified yet. In this study, developing the previous works, additional CFD simulations are conducted to examine the generation process and particularly the stability of fire whirls. Three schemes to generate fire whirls are employed, using the 15 × 15 PMMA fuel array in windy conditions and n-heptane burning in a steel pan placed centrally on the floor in a tall channel with staggered four corner gaps, also using a channel with a single corner gap. The numerical results showed that the relationship between the fire area and the wind blowing area is important on the fire whirl generation in the PMMA scheme and n-heptane fire burning scheme in a channel. In addition to the channel gap size to produce a maximum fire whirl, the effects of channel height and horizontal channel area upon the fire whirl are examined. The wall temperatures of the channel are important to keep the swirling motion stably, particularly the wall temperature at about 300°C can stabilize the fire whirl in a channel. Also multiple small fires placed surrounding the central swirling fire can increase the stability of the fire whirl, although too strong multiple fires may destroy the stability. These phenomena may be related to the real fire whirl generation in the natural environment.
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Lee, M. H., J. H. Lee i G. H. Jang. "Stability Analysis of a Whirling Rigid Rotor Supported by FDBs Considering Five Degrees of Freedom of a General Rotor-Bearing System". W ASME 2014 Conference on Information Storage and Processing Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/isps2014-6932.

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A rotor supported by fluid dynamic bearings (FDBs) has a whirling motion by centrifugal force due to the mass unbalance or by the flexibility of shaft. This whirling motion also generates periodic time-varying oil-film reaction and dynamic coefficients even in case of the stationary grooved FDBs. This paper proposes a method to determine the stability of a whirling rotor supported by stationary grooved FDBs considering five degrees of freedom of a general rotor-bearing system. Dynamic coefficients are calculated by using the finite element method and the perturbation method, and they are represented as periodic harmonic functions by considering whirling motion. Because of the periodic time-varying dynamic coefficients, the equations of motion of the rotor supported by FDBs can be represented as a parametrically excited system. The solution of the equations of motion can be assumed as the Fourier series so that the equations of motion can be rewritten as simultaneous algebraic equations with respect to the Fourier coefficients. Hill’s infinite determinant is calculated by using these algebraic equations in order to determine the stability. The stability of the FDBs decreases with the increase of rotational speed. The stability of the FDBs increases with the increase of whirl radius, because the average and variation of Cxx increase faster than those of Kxx. The proposed method is verified by solving the equations of motion by using the forth Runge-Kutta method to determine the convergence and divergence of whirl radius.
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Hariharan, Sriram Bharath, Xiao Zhang, Joseph Chung, Yejun Wang, Waruna Kulatilaka, Michael Gollner i Elaine Oran. "Video: Understanding whirling flames". W 73th Annual Meeting of the APS Division of Fluid Dynamics. American Physical Society, 2020. http://dx.doi.org/10.1103/aps.dfd.2020.gfm.v0080.

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Raporty organizacyjne na temat "Whirlin"

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Battaglia, Francine, Kevin B. McGrattan, Ronald G. Rehm i Howard R. Baum. Simulating fire whirls. Gaithersburg, MD: National Institute of Standards and Technology, 1999. http://dx.doi.org/10.6028/nist.ir.6341.

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Pearce, Lauren. A Whirlwind History of Cryptography. Office of Scientific and Technical Information (OSTI), październik 2020. http://dx.doi.org/10.2172/1671059.

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Luketa, Anay. Fire Whirl Investigation. Office of Scientific and Technical Information (OSTI), wrzesień 2018. http://dx.doi.org/10.2172/1472227.

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Fowler, T. K. Whirl plus tilt. Office of Scientific and Technical Information (OSTI), październik 1994. http://dx.doi.org/10.2172/10121834.

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Battaglia, Francine, Ronald G. Rehm i Howard R. Baum. The fluid dynamics of fire whirls:. Gaithersburg, MD: National Institute of Standards and Technology, 2000. http://dx.doi.org/10.6028/nist.ir.6427.

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Johnsen, William T. NATO Strategy in the 199Os: Reaping the Peace Dividend or the Whirlwind? Fort Belvoir, VA: Defense Technical Information Center, maj 1995. http://dx.doi.org/10.21236/ada297790.

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Whirl Analysis of an Overhung Disk Shaft System Mounted on Non-rigid Bearings. SAE International, marzec 2022. http://dx.doi.org/10.4271/2022-01-0607.

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Eigenvalues of a simple rotating flexible disk-shaft system are obtained using different methods. The shaft is supported radially by non-rigid bearings, while the disk is situated at one end of the shaft. Eigenvalues from a finite element and a multi-body dynamic tool are compared against an established analytical formulation. The Campbell diagram based on natural frequencies obtained from the tools differ from the analytical values because of oversimplification in the analytical model. Later, detailed whirl analysis is performed using AVL Excite multi-body tool that includes understanding forward and reverse whirls in absolute and relative coordinate systems and their relationships. Responses to periodic force and base excitations at a constant rotational speed of the shaft are obtained and a modified Campbell diagram based on this is developed. Whirl of the center of the disk is plotted as an orbital or phase plot and its rotational direction noted. Finally, based on the above plots, forward and reverse whirl zones for the two excitation types are established.
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