Artykuły w czasopismach: „Vitamins in human nutrition”

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Kravtsova, E. I., I. I. Kutsenko, I. O. Borovikov i S. K. Batmen. "Nutrition and nutritional support during pregnancy". Russian Journal of Woman and Child Health 3, nr 4 (2020): 233–41. http://dx.doi.org/10.32364/2618-8430-2020-3-4-233-241.

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Increased nutrient needs during pregnancy are accounted for by physiological changes in the maternal organism and requirements of the developing and growing baby. They are realized through a number of physiological adaptations in nutrient metabolism. Physiological pregnancy and adequate fetal development are impossible in deficient nutrients, vitamins, and microelements. Randomized clinical trials in pregnant women have demonstrated that nutrient deficiency in the maternal organism results in pregnancy complications and health problems in the newborn but also accounts for a wide range of chronic disorders among the offspring. Probiotics improve digestive health in pregnant women and affect epigenetic programming of human homeostasis that predisposes to dysbiosis, allergies, and lipid and carbohydrate metabolism disorders. Prevention of vitamin and probiotic deficiency during pre-pregnancy planning, pregnancy, and breastfeeding focuses on ensuring that vitamin intake from food meets the requirements for these nutrients. Complex vitamin supplements containing probiotics treat alimentary deficiency and contribute to the favorable course of pregnancy and fetal development. KEYWORDS: nutrition, woman’s health, pregnancy, vitamins, probiotics, nutrient deficiency. FOR CITATION: Kravtsova E.I., Kutsenko I.I., Borovikov I.O., Batmen S.K. Nutrition and nutritional support during pregnancy. Russian Journal of Woman and Child Health. 2020;3(4):233–240. DOI: 10.32364/2618-8430-2020-3-4-233-241.

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Semba, Richard D. "The Discovery of the Vitamins". International Journal for Vitamin and Nutrition Research 82, nr 5 (1.10.2012): 310–15. http://dx.doi.org/10.1024/0300-9831/a000124.

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The discovery of the vitamins was a major scientific achievement in our understanding of health and disease. In 1912, Casimir Funk originally coined the term vitamine. The major period of discovery began in the early nineteenth century and ended at the mid-twentieth century. The puzzle of each vitamin was solved through the work and contributions of epidemiologists, physicians, physiologists, and chemists. Rather than a mythical story of crowning scientific breakthroughs, the reality was a slow, stepwise progress that included setbacks, contradictions, refutations, and some chicanery. Research on the vitamins that are related to major deficiency syndromes began when the germ theory of disease was dominant and dogma held that only four nutritional factors were essential: proteins, carbohydrates, fats, and minerals. Clinicians soon recognized scurvy, beriberi, rickets, pellagra, and xerophthalmia as specific vitamin deficiencies, rather than diseases due to infections or toxins. Experimental physiology with animal models played a fundamental role in nutrition research and greatly shortened the period of human suffering from vitamin deficiencies. Ultimately it was the chemists who isolated the various vitamins, deduced their chemical structure, and developed methods for synthesis of vitamins. Our understanding of the vitamins continues to evolve from the initial period of discovery.

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Azzini, Elena, Tiziano Furini, Angela Polito, Luca Scalfi, Alessandro Pinto, Valeria Gasperi i Isabella Savini. "Vitamin Nutritional Status in Patients with Pancreatic Cancer: A Narrative Review". International Journal of Molecular Sciences 25, nr 9 (27.04.2024): 4773. http://dx.doi.org/10.3390/ijms25094773.

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Due to the high mortality rate in Western countries, pancreatic cancer is considered one of the big killers, leaving patients and their families with little hope upon diagnosis. Although surgical and drug therapies are critical for cancer patients to improve life expectancy and alleviation of suffering, nutrition plays a key role in improving cancer treatment outcomes. This narrative review, conducted as part of the activities of the Italian Society of Human Nutrition (SINU) working group in oncology, focuses on the prevalence of vitamin malnutrition among pancreatic cancer patients. The results of the literature search show that pancreatic cancer patients are at a heightened risk of water-soluble vitamin deficiencies, particularly of vitamins B1, B3, and B6. Additionally, they also face an increased risk of deficiency of fat-soluble vitamins. Among these vitamins, the potential role of vitamin D in pancreatic cancer has garnered the most attention, with its plasma levels being identified as a significant factor in patient survival. Investigating vitamin nutritional status could provide valuable insights for incorporating nutritional approaches into the prevention and treatment of pancreatic cancer, thereby reducing the exacerbation of symptoms associated with the diagnosis.

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Morris, James G. "Vitamins in Animal and Human Nutrition". American Journal of Clinical Nutrition 74, nr 3 (1.09.2001): 413. http://dx.doi.org/10.1093/ajcn/74.3.413.

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Ali, Mennatallah A., Hala A. Hafez, Maher A. Kamel, Heba I. Ghamry, Mustafa Shukry i Mohamed A. Farag. "Dietary Vitamin B Complex: Orchestration in Human Nutrition throughout Life with Sex Differences". Nutrients 14, nr 19 (22.09.2022): 3940. http://dx.doi.org/10.3390/nu14193940.

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The importance of B complex vitamins starts early in the human life cycle and continues across its different stages. At the same time, numerous reports have emphasized the critical role of adequate B complex intake. Most studies examined such issues concerning a specific vitamin B or life stage, with the majority reporting the effect of either excess or deficiency. Deep insight into the orchestration of the eight different B vitamins requirements is reviewed across the human life cycle, beginning from fertility and pregnancy and reaching adulthood and senility, emphasizing interactions among them and underlying action mechanisms. The effect of sex is also reviewed for each vitamin at each life stage to highlight the different daily requirements and/or outcomes. Thiamine, riboflavin, niacin, pyridoxine, and folic acid are crucial for maternal and fetal health. During infancy and childhood, B vitamins are integrated with physical and psychological development that have a pivotal impact on one’s overall health in adolescence and adulthood. A higher intake of B vitamins in the elderly is also associated with preventing some aging problems, especially those related to inflammation. All supplementation should be carefully monitored to avoid toxicity and hypervitaminosis. More research should be invested in studying each vitamin individually concerning nutritional disparities in each life stage, with extensive attention paid to cultural differences and lifestyles.

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Norbitt, Claire F., Wandia Kimita, Sakina H. Bharmal, Juyeon Ko i Maxim S. Petrov. "Relationship between Habitual Intake of Vitamins and New-Onset Prediabetes/Diabetes after Acute Pancreatitis". Nutrients 14, nr 7 (1.04.2022): 1480. http://dx.doi.org/10.3390/nu14071480.

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Vitamins have many established roles in human health. However, the role of habitual dietary intake of vitamins in glucose homeostasis in individuals after acute pancreatitis (AP) is yet to be elucidated. The aim was to investigate the associations between habitual intake of fat- and water-soluble vitamins/vitamers and markers of glucose metabolism (fasting plasma glucose (FPG), homeostasis model assessment insulin resistance (HOMA-IR) index, and homeostasis model assessment β-cell function (HOMA-β)) in individuals after AP. A total of 106 participants after AP were included in this cross-sectional study and were grouped based on glycaemic status: new-onset prediabetes/diabetes after AP (NODAP), pre-existing prediabetes/type 2 diabetes (T2DM), and normoglycaemia after AP (NAP). Habitual intake of seven fat-soluble vitamins/vitamers and seven water-soluble vitamins were determined by the EPIC-Norfolk food frequency questionnaire. Multiple linear regression analyses were conducted using five statistical models built to adjust for covariates (age, sex, daily energy intake, visceral/subcutaneous fat volume ratio, smoking status, daily alcohol intake, aetiology of AP, number of AP episodes, cholecystectomy, and use of antidiabetic medications). In the NODAP group, three fat-soluble vitamins/vitamers (α-carotene, β-carotene, and total carotene) were significantly associated with HOMA-β. One water-soluble vitamin (vitamin B3) was also significantly associated with HOMA-β in the NODAP group. None of the studied vitamins were significantly associated with FPG or HOMA-IR in the NODAP group. Prospective longitudinal studies and randomised controlled trials are now warranted to investigate if the observed associations between vitamin/vitamer intake and NODAP are causal and to unveil the specific mechanisms underlying their involvement with NODAP.

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Ivanov, V., S. Ivanova, A. Niedzwiecki i M. Rath. "Fat-Soluble Vitamins Affect Composition of Extracellular Matrix Deposited by Human Aortic Smooth Muscle and Endothelial Cells In Vitro". Current Topics in Nutraceutical Research 19, nr 1 (6.07.2020): 36–45. http://dx.doi.org/10.37290/ctnr2641-452x.19:36-45.

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Atherosclerotic cardiovascular disease is accompanied by changes in arterial connective tissue. We evaluated the effects of fat-soluble vitamins A, D, and E individually and in combinations on the composition of extracellular matrix produced and deposited by arterial wall cells, human aortic smooth muscle cells, and endothelial cells. Individually, vitamins D and E stimulated collagen type I extracellular matrix deposition in human aortic smooth muscle cell cultures. However, vitamins A, D, and E reduced collagen type IV deposition by human aortic smooth muscle cell, counteracting the stimulatory effects of vitamin C. The extracellular matrix deposition of heparan sulfate by human aortic smooth muscle cells increased by vitamin C and its combination (C+D+E). β-carotene + D + C induced the extracellular matrix deposition of collagen I by endothelial cells. Vitamin E with other vitamins resulted in either induction (E+C+A) or inhibition (E+D). The extracellular matrix deposition of type IV collagen and elastin by human aortic endothelial cells was not affected by test vitamins, except the extracellular matrix type IV collagen decrease by combinations (A+E), (A+D+E), and (C+D+E). The extracellular matrix deposition of all tested glycosaminoglycans was reduced by vitamin A and its combination (A+C+D+E). Therefore, the fat-soluble vitamins applied individually or in combination—both with each other or with ascorbic acid—can affect extracellular matrix deposition of type I and IV collagens, and key glycosaminoglycans by cultured human aortic arterial wall cells.

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Woźniak, Dagmara, Wojciech Cichy, Małgorzata Dobrzyńska, Juliusz Przysławski i Sławomira Drzymała-Czyż. "Reasonableness of Enriching Cow’s Milk with Vitamins and Minerals". Foods 11, nr 8 (8.04.2022): 1079. http://dx.doi.org/10.3390/foods11081079.

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Milk is an exceptional nutritional product that has been used for many millennia in human nutrition. Milk is a source of many valuable nutrients, including calcium, vitamin B, an especially significant amount of vitamin B2 and fat-soluble vitamins, such as A, D and E. Milk is an attractive product for fortification as it has a high nutritional density in a small volume and a relatively low price. Research shows positive health effects of drinking milk and consuming dairy products. Even more health benefits can be obtained from consuming fortified dairy products. A literature review, current nutritional recommendations, medical recommendations and an analysis of the market situation all recommend introducing milk enriched with minerals in combination with vitamins to the market. This concept corresponds to the current market demand and may supplement the missing and expected range of fortified milk and the correct number of recipients.

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Zołoteńka-Synowiec, Marzena, Beata Całyniuk, Ewa Malczyk, Aleksandra Zgraja i Marta Misiarz. "Content of selected vitamins in menus from a social welfare home". Medical Science Pulse 12, nr 3 (30.09.2018): 18–21. http://dx.doi.org/10.5604/01.3001.0012.6142.

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Background: Psychological old age is considered a developmental process in which there is a juxtaposition of profit and loss. Developmental changes are multi-faceted and include biological, psychological and social spheres. The quality of human life diminishes as mobility lessens, and this compromises self-perception. The biological changes of old age are retroactive. Poor nutritional status and other negative behaviors like addictions contribute to the physiological regression of aging. Interest in nutrition amongst the elderly is heightened because of the aging population in Poland and internationally. There is also interest in the application of proper nutrition to prevent diseases in this age group. Proper nutrition is one of the main factors determining ideal human function and positively affects the natural processes within it. Analysis of food composition gives the opportunity to eliminate nutritional errors, which in turn contributes to improving the quality of life and delaying the aging process in the examined age group. Aim of the study: The aim of this study was to evaluate the content of selected vitamins in 10 seasonal menus applied at a Social Welfare Home. Material and methods: This study included 40 decade menus, prepared over four seasons of a year for the residents of a Social Welfare Home. The vitamin content of the meals was assessed quantitatively using the computer program, Diet 5. The selected vitamins were those considered most essential to the elderly diet because of the common appearance of their deficiencies. Taking into consideration physical activity of the elderly (1,4 physical activity level ) and utilizing the norms developed by the Food and Nutrition Institute, the average norms of the analyzed nutrients were calculated for people over 60 years of age. For this purpose the formula (K+M)/2 was used, where K is the norm for women and M is the norm for men. The results obtained were compared with the calculated mean values of the norm for elderly at the level of the estimated average requirements (EAR). The results were analyzed statistically giving the mean value (X) and the median. The calculations were performed using Microsoft Excel. Results: Deficiencies in vitamin D were found. The menu content of vitamins E and C was correct in all seasons. The amount of vitamins A, B2, B12 and PP was excessive in all the seasons. Conclusions: The evaluated menus showed errors in the supply of the assessed vitamins.

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Kotake-Nara, Eiichi, Shiro Komba i Megumi Hase. "Uptake of Vitamins D2, D3, D4, D5, D6, and D7 Solubilized in Mixed Micelles by Human Intestinal Cells, Caco-2, an Enhancing Effect of Lysophosphatidylcholine on the Cellular Uptake, and Estimation of Vitamins D’ Biological Activities". Nutrients 13, nr 4 (29.03.2021): 1126. http://dx.doi.org/10.3390/nu13041126.

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Vitamins D have various biological activities, as well as intestinal calcium absorption. There has been recent concern about insufficient vitamin D intake. In addition to vitamins D2 and D3, there are lesser-known vitamins D4–D7. We synthesized vitamins D5–D7, which are not commercially available, and then evaluated and compared the mixed micelles-solubilized vitamins D uptake by Caco-2 cells. Except for vitamin D5, the uptake amounts of vitamins D4–D7 by differentiated Caco-2 cells were similar to those of vitamins D2 and D3. The facilitative diffusion rate in the ezetimibe inhibited pathway was approximately 20% for each vitamin D type, suggesting that they would pass through the pathway at a similar rate. Lysophosphatidylcholine enhanced each vitamin D uptake by approximately 2.5-fold. Lysophosphatidylcholine showed an enhancing effect on vitamin D uptake by reducing the intercellular barrier formation of Caco-2 cells by reducing cellular cholesterol, suggesting that increasing the uptakes of vitamins D and/or co-ingesting them with lysophosphatidylcholine, would improve vitamin D insufficiency. The various biological activities in the activated form of vitamins D4–D7 were estimated by Prediction of Activity Spectra for Substances (PASS) online simulation. These may have some biological activities, supporting the potential as nutritional components.

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Vincenzetti, Silvia, Giuseppe Santini, Valeria Polzonetti, Stefania Pucciarelli, Yulia Klimanova i Paolo Polidori. "Vitamins in Human and Donkey Milk: Functional and Nutritional Role". Nutrients 13, nr 5 (29.04.2021): 1509. http://dx.doi.org/10.3390/nu13051509.

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Background: Whole milk is a good source of all the nutrients, and it also contains a sufficient number of vitamins to permit regular the growth of the neonate. Dairy cow milk can create allergy in infants less than 12 months old because of the high caseins and β-lactoglobulin content. In these circumstances, donkey milk can represent a good replacement for dairy cows’ milk in children affected by Cow Milk Protein Allergy (CMPA) because of its close chemical composition with human milk, mainly due to its low protein and low mineral content. Milk vitamin content is highly variable among mammalian species and it is strictly correlated with the vitamin status and the diet administered to the mother. Fat-soluble vitamins content in donkey milk is, on average, lower compared to ruminants’ milk, while vitamin C content determined in donkey milk is higher compared to dairy cows’ milk, showing a great similarity with human milk. In donkey milk, the content of vitamins of the B-complex such as thiamine, riboflavin, niacin, pyridoxine, and folic acid is higher compared to human milk. The use of donkey milk as a new functional food must be further evaluated in interdisciplinary clinical trials in which pediatricians, dietitians, and food scientists must be involved to deepen the knowledge about the positive health impact of donkey milk in different sensitive people, especially children and the elderly.

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Starostina, L. S. "Vitamin and mineral supply in children: a pediatrician’s view". Russian Journal of Woman and Child Health 3, nr 4 (2020): 319–25. http://dx.doi.org/10.32364/2618-8430-2020-3-4-319-325.

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The important role of vitamins for bodily functions was described for the first time by Russian pediatrician N.I. Lunin as early as in 1880. Since then, doctors, biologists, researchers, and other experts have focused on the effects of vitamins on human body and their role in various processes. In 2017, the Union of Pediatricians of Russia has developed “National program of the optimization of vitamin and mineral supply of Russian children” based on the monitoring of child nutrition. Treatment of multivitamin deficiency involves additional intake of missing substances as well as the improvement of their absorption and their synthesis in human body. The vast majority of vitamin and mineral supplements contain daily-recommended amounts of essential vitamins and microelements. However, not all substances are completely absorbed since patients with multivitamin deficiency often have gut microbiome abnormalities resulting in poor availability of supplemented vitamins and minerals. This paper discusses the rationale of additional vitamins, their role in bodily functions, and signs of vitamin deficiency. KEYWORDS: children, prevention, vitamins, microelements, macroelements, micronutrients, harmonious development, immunity, microbiota, Bifidobacterium. FOR CITATION: Starostina L.S. Vitamin and mineral supply in children: a pediatrician’s view. Russian Journal of Woman and Child Health. 2020;3(4):319–324. DOI: 10.32364/2618-8430-2020-3-4-319-325.

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Пономарева, Елена, Elena Ponomareva, Андрей Кривошеев, Andrey Krivosheev, Светлана Лукина, Svetlana Lukina, Надежда Алехина i in. "Breadsticks with enhanced nutritional value for salt-free nutrition". Food Processing: Techniques and Technology 48, nr 1 (10.01.2019): 114–24. http://dx.doi.org/10.21603/2074-9414-2018-1-114-124.

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At present moment it is essential to produce food which not only satisfies people’s needs, but also has a particular nutritional value and vitamin and mineral content. Introduction of non-traditional types of plant materials in the recipes of baked goods for preventive and therapeutic nutrition is a promising direction for enhancing their nutritional value. Consumption of these products improves the balance of vitamins, amino acids, trace elements, macronutrients, food fibers and has a positive effect on human health. The article presents the development of breadstick recipe for salt-free nutrition using flax seed flour and grapeseed oil which guarantee overall enrichment of food recommended in case of such diseases as heart and renal failure, hypertension, osteoporosis, arthritis and arthrosis. Using flax seed flour in baked goods production will make it possible to increase the content of protein, food fibers, vitamins and mineral substances in them. Grapeseed oil has a lot of polyunsaturated fatty acids and biologically active substances which improve immune barrier. The article reveals the results of the determination of the table salt effect as well as the influence of non-traditional types of raw materials on organoleptic, physical and chemical parameters of the ready-to-use products, their microstructure and antioxidant activity. The author suggests using enzymatic composition instead of table salt in breadsticks recipe for salt-free nutrition. The article presents the results of the chemical composition determination and calculation of breadsticks nutritional value. The obtained data will help extend the product line of special-use baked goods with higher nutritional value.

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Kampuse, Solvita, Liene Ozola, Zanda Krūma, Dace Kļava, Ruta Galoburda, Evita Straumīte i Inese Siksna. "Nutritional Composition of Plant-Based Texture: Modified Foods for Dysphagia Patients". Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 76, nr 1 (1.02.2022): 22–29. http://dx.doi.org/10.2478/prolas-2022-0004.

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Abstract There are approximately 590 million people in the world with swallowing disorders (dysphagia), who need texture-modified foods to ensure nutritional intake on a daily basis. The aim of this research was to create new texture-modified products and to evaluate their bioactive and mineral compound concentration. Nine new products (five desserts and four puree-soups) were developed from plant-based ingredients with addition of a source of protein, canola oil, ascorbic acid, and other ingredients. Obtained samples were vacuum-cooked, sterilised at 115 °C for 5 min and tested for their bioactive compound concentration (total carotene and phenol concentration, and ABTS and DPPH radical scavenging activity), and concentration of seven vitamins and thirteen minerals important in human nutrition. The obtained data showed that bioactive compound concentration varied from sample to sample, which was expected due to the varied ingredients of each product. Mineral compound concentration analysis showed low levels of iodine, molybdenum, and selenium. The vitamin analysis showed traces of vitamin D3 and low levels of B group vitamins. Overall, the analysed product composition indicated that the natural background of these products is insufficient for ensuring the human body with all of the necessary vitamins and minerals, and the best solution could be the supplementation of these products with complexes of vitamins and minerals.

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Melanson, Kathleen J. "Nutrition Review: Diet, Nutrition, and Osteoarthritis". American Journal of Lifestyle Medicine 1, nr 4 (lipiec 2007): 260–63. http://dx.doi.org/10.1177/1559827607302033.

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Despite abundant lay claims regarding diet, nutrients, and osteoarthritis (OA), scientific study on these relationships is in its early stages. The strongest risk factor for OA, particularly of the knee, is overweight and obesity. Initial weight loss studies for the treatment of OA have shown promising results, but longer-term trials are needed. Potential roles of specific nutrients in OA prevention and treatment are under study, but to date, results are somewhat less clear. The ratio of dietary omega-6 to omega-3 fatty acids has been proposed to be related to OA because they are precursors of proinflammatory and anti-inflammatory eicosanoids and cytokines, respectively. However, human data are lacking to substantiate this relationship. Low serum levels of some vitamins, such as C and D, have been associated with OA in epidemiological research, but much more work must be conducted to understand the roles of these and other vitamins in OA prevention and treatment. Biological plausibility exists for the protective properties of antioxidants against OA, so continued research to assist in making specific dietary recommendations with respect to these is needed for OA patients. As the study of diet, nutrients, and OA evolves, it is prudent for practitioners to stay abreast of the research so that they can address patients' questions and recommend diets with adequate omega-3 fatty acids, vitamins, minerals, and antioxidants while avoiding megadoses.

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Bates, C. J., i H. Heseker. "Human Bioavailability of Vitamins". Nutrition Research Reviews 7, nr 1 (styczeń 1994): 93–127. http://dx.doi.org/10.1079/nrr19940008.

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Mewes, Louisa, Carina Knappe, Christian Graetz, Juliane Wagner, Tobias J. Demetrowitsch, Julia Jensen-Kroll, Karim Mohamed Fawzy El-Sayed i in. "Vitamin C and Omega-3 Fatty Acid Intake Is Associated with Human Periodontitis—A Nested Case-Control Study". Nutrients 14, nr 9 (5.05.2022): 1939. http://dx.doi.org/10.3390/nu14091939.

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Vitamins and omega-3 fatty acids (Ω3FA) modulate periodontitis-associated inflammatory processes. The aim of the current investigation was to evaluate associations of oral nutrient intake and corresponding serum metabolites with clinical severity of human periodontitis. Within the Food Chain Plus cohort, 373 periodontitis patients—245 without (POL) and 128 with tooth loss (PWL)—were matched to 373 controls based on sex, smoking habit, age and body mass index in a nested case-control design. The amount of oral intake of vitamins and Ω3FAs was assessed from nutritional data using a Food Frequency Questionnaire. Oral intake and circulatory bioavailability of vitamins and Ω3FA serum metabolomics were compared, using ultra-high-resolution mass spectrometry. Periodontitis patients exhibited a significantly higher oral intake of vitamin C and Ω3FA Docosapentaenoic acid (p < 0.05) compared to controls. Nutritional intake of vitamin C was higher in PWL, while the intake of Docosapentaenoic acid was increased in POL (p < 0.05) compared to controls. In accordance, serum levels of Docosapentaenoic acid were also increased in POL (p < 0.01) compared to controls. Vitamin C and the Ω3FA Docosapentaenoic acid might play a role in the pathophysiology of human periodontitis. Further studies on individualized nutritional intake and periodontitis progression and therapy are necessary.

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Campos, Paixão i Ferraz. "Fat-Soluble Vitamins in Human Lactation". International Journal for Vitamin and Nutrition Research 77, nr 5 (1.09.2007): 303–10. http://dx.doi.org/10.1024/0300-9831.77.5.303.

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Lactation has three distinct phases: colostrum, transition, and mature, with the quantity of fat-soluble vitamins and carotenoids tending to decline while the total fat content increases. The number of deliveries seems to be directly related to higher concentrations of beta-carotene and vitamin E in colostrum. Little is known about vitamin quantities during the other phases. In the present study, vitamin A and E concentrations during different phases of lactation were measured in primiparous and multiparous mothers to analyze the variation and suitability for the diet of a breastfed child. Phase of lactation and number of deliveries were highly significant for log mean vitamin A while only one phase showed significance for log mean vitamin E. There was a sharp decline in the levels of vitamin A and E in the course of the initial phase of lactation. The variability between measurements declined as colostrum transitioned to mature milk. There were significant measurable inter-group differences in retinol levels in milk obtained during early lactation. Vitamin A and E content can reach 2.5 and 1.4 times of levels recommended intake, respectively.

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Vitkova, Tsvetelina, Rositsa Enikova, Milena Karcheva i Plamen Saraliev. "EGGS IN THE HUMAN DIET - FACTS AND CHALLENGES". Journal of IMAB - Annual Proceeding (Scientific Papers) 30, nr 1 (18.01.2024): 5314–22. http://dx.doi.org/10.5272/jimab.2024301.5314.

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Eggs are a good source of balanced nutritional and biologically active substances - proteins, lipids, some irreplaceable nutritional components such as amino acids, polyunsaturated fatty acids, vitamins, macro- and microelements, etc. It is identified as the cheapest animal source of proteins, lipids, vitamins A, B12, riboflavin, choline, iron, zinc, phosphorus and calcium. At the same time, the dangers to human health that eggs can carry are also taken into account. Material/Methods: The literature used is based on databases PubMed, Embase and as well as data from own studies. Review Results: In the present review, we provide data on the importance of the composition of eggs in human nutrition are presented and the risk of their use is evaluated. Conclusions: The high biological and nutritional value of eggs are grounds for their use in the daily life of healthy people, without additional restrictions of cardiovascular diseases. There is a risk of food poisoning, which can be limited to acceptable levels by following good hygiene practices.

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Juszczak, Aleksandra Beata, Maciej Kupczak i Tomasz Konecki. "Does Vitamin Supplementation Play a Role in Chronic Kidney Disease?" Nutrients 15, nr 13 (23.06.2023): 2847. http://dx.doi.org/10.3390/nu15132847.

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Although the role of vitamins in the human body is proven, guidelines for patients with chronic kidney disease (CKD) remain unclear. This narrative review summarizes the findings of 98 studies of CKD and the effects of vitamin D, B, C, A, E, and K supplementation on patients on dialysis for CKD, with the aim of summarizing the existing guidelines. The findings are promising, showing the potential effectiveness of vitamin supplementation with, for example, vitamins B, D, or C. However, recommendations are still ambiguous, especially in the case of vitamins A and K, due to the potential toxicity associated with higher doses for patients. Continued research is needed to rigorously evaluate the effectiveness and carefully consider the potential risks of some vitamin supplementation for patients with CKD.

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Csapó, J., Cs Albert i J. Prokisch. "The role of vitamins in the diet of the elderly II. Water-soluble vitamins". Acta Universitatis Sapientiae, Alimentaria 10, nr 1 (1.10.2017): 146–66. http://dx.doi.org/10.1515/ausal-2017-0010.

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AbstractFollowing a presentation of humans’ water-soluble vitamin requirements, the authors will discuss in detail the role these vitamins play in human organism and outline those major biochemical processes that are negatively affected in the body in case of vitamin deficiency. They point out that in the elderly population of developed countries cases of water-soluble vitamin deficiency are extremely rare and they are due to the lack of dietary vitamin, but mostly to the vitamin being released from its bindings, the difficulty of free vitamin absorption, gastrointestinal problems, medication, and often alcoholism. Among water-soluble vitamins, B12is the only one with a sufficient storage level in the body, capable of preventing deficiency symptoms for a long period of time in cases of vitamin-deficient nutrition. Each type of vitamin is dealt with separately in discussing the beneficial outcomes of their overconsumption regarding health, while the authors of the article also present cases with contradictory results. Daily requirements are set forth for every water-soluble vitamin and information is provided on the types of nutrients that help us to the water-soluble vitamins essential for the organism.

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Dounousi, Evangelia, i Vasillios Liakopoulos. "Editorial for the Special Issue “Vitamin K in Chronic Disease and Human Health”". Nutrients 14, nr 13 (23.06.2022): 2595. http://dx.doi.org/10.3390/nu14132595.

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Nguyen, My Tuyen Thi, Jieun Kim, Hyunjun Lee, Soyoon Won, Yongki Kim, Ji A. Jung, Dan Li i in. "A Comparison of Vitamin and Lutein Concentrations in Breast Milk from Four Asian Countries". Nutrients 12, nr 6 (17.06.2020): 1794. http://dx.doi.org/10.3390/nu12061794.

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Vitamins are the essential elements for human life and, particularly, for infant health. Human milk is the best source of nutrients for newborns, however, the information of vitamins in Asian maternal milk is still limited. In this study, we have collected 580 Asian maternal milk samples from Korea (n = 254), China (n = 137), Pakistan (n = 92), and Vietnam (n = 97). The vitamin concentrations, including vitamin B-groups (8 vitamins), fat-soluble vitamin (retinol, D, E, K) and lutein in the breast milk of were investigated. The concentration of thiamin (B1), biotin (B7), and folic acid (B9) in mother’s milk of four countries were not considerably different, while riboflavin (B2), pantothenic acid (B5), and pyridoxine (B6) level in Vietnam samples were significantly lower than those in other countries. In contrast, retinol (A) and tocopherol (E) were found to be higher levels in Vietnamese maternal milk. Korean and Chinese maternal milk had low concentrations of retinol that may cause vitamin A deficiency in children. However, Chinese mother’s milk was distinguished with a high concentration of lutein. Pakistani mother’s milk was observed as having a significant problem of folic acid (B9) deficiency. Regardless of the country, vitamin B12, K, and D did not seem to be provided sufficiently through maternal milk. The moderate positive correlations were found between vitamin concentrations in each country and the pooled sample. The data obtained in this study were able to provide vital information to assess the nutritional status of breast milk in Asian countries and contributed to the efforts of ensuring the best nutrition for Asian children.

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Amarowicz, Ryszard. "Legume Seeds as an Important Component of Human Diet". Foods 9, nr 12 (7.12.2020): 1812. http://dx.doi.org/10.3390/foods9121812.

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Hampel, Daniela, Setareh Shahab-Ferdows, Kerry Schulze i Lindsay Allen. "Comprehensive Analysis of B-vitamins in Human Milk". Current Developments in Nutrition 6, Supplement_1 (czerwiec 2022): 766. http://dx.doi.org/10.1093/cdn/nzac063.008.

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Abstract Objectives B-vitamins are metabolic co-factors and an inadequate supply to the exclusively breast-fed infant can affect healthy growth and development. We developed a UPLC-MS/MS method for analyzing thiamin (T), thiamin-monophosphate, riboflavin, flavin adenine dinucleotide, flavin mononucleotide, nicotinamide, nicotinic acid, nicotinamide mononucleotide, nicotinamide dinucleotide, nicotinamide riboside, nudifloramide, pantothenic acid, pyridoxal, pyridoxal 5-phosphate, pyridoxamine, pyridoxine, 4-pyridoxic acid, biotin, 5-methyl-tetrahydrofuran (5MeTHF), and tryptophan in human milk. Methods Optimized results were obtained using a Phenomenex NX-C18 column, 250 × 3 mm, 3 µm, and a gradient of an aqueous solution of 10 mM ammonium formate + 0.05% ammonium hydroxide (A) and acetonitrile (B) from 99% to 5% A in a 12 min run (SCIEX ExionLC-AD -QTRAP6500+). Defatted and deproteinized milk (100 µL) was used and quantified by area ratio responses (external to internal standards). 50 milk samples from community-dwelling rural Bangladeshi mothers at 3.2 ± 0.2 months postpartum were analyzed and results were compared to the Adequate Intakes (AI) for infants 0–6 months. Results Analyte recoveries in pooled human milk ranged from 65–130% across vitamins with an overall process efficiency from 81–92% (T: 190%). Additional analytes were detectable but not yet quantifiable: nicotinamide dinucleotidephosphate, pyridoxamine 5-phosphate, 4-deoxypyridoxine, folic acid, and thiamin-diphosphate. 5MeTHF was detectable but given the sample preparation, only as a small concentration. Milk from Bangladeshi mothers had a large range of vitamin concentrations within and between analytes, including for samples meeting the AI. One sample (2%) reached the AI for vitamin B1, none for B2; 14% for niacin, 98% for pantothenic acid, 72% for B6, and 34% for biotin. Conclusions This method enables a comprehensive evaluation of milk B-vitamin concentrations to assess status and effects of maternal interventions on milk B-vitamins. Future application will be expanded to other matrices with further validation of the analytes currently only ascertainable qualitatively. Funding Sources Bill & Melinda Gates Foundation (OPP1148405), USDA/ARS Intramural Project (5306-51,530-019-00).

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Levêques, Antoine, Jean-Marie Oberson, Emeline Alexandra Tissot, Karine Redeuil, Sagar K. Thakkar i Esther Campos-Giménez. "Quantification of Vitamins A, E, and K and Carotenoids in Submilliliter Volumes of Human Milk". Journal of AOAC INTERNATIONAL 102, nr 4 (1.07.2019): 1059–68. http://dx.doi.org/10.5740/jaoacint.19-0016.

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Abstract Background: Human milk is the optimal nutrition for all newborns in the first 6 months of life. In order to assess the nutritional needs of the breastfed infant, human milk is often characterized for multiple nutrients. Objective: To ensure that we minimize the volume of milk dedicated for research and optimize the number of nutrients characterized, we developed analytical methodologies for the determination of vitamins A (retinol), E (alpha and gamma tocopherol), K (phylloquinone and menaquinone-4), and five carotenoids (β-carotene, lycopene, β-cryptoxanthin, lutein, and zeaxanthin) using <1 mL human milk. Method: Vitamins E and K and carotenoids are simultaneously isolated from 750 μL milk by liquid–liquid extraction (LLE). Tocopherols and carotenoids are determined by normal-phase LC with fluorescence and ultraviolet detection respectively. Vitamin K is analyzed on the same extracts after resuspension and clean-up by reversed phase liquid chromatography coupled to tandem MS. The analysis of vitamin A involves saponification of 200 μL milk followed by LLE and determination by normal-phase LC with UV detection. Results: Full single-laboratory validation at four different concentration levels is presented. Recovery rates were within 90–105% in all except one case (retinol at 1.9 μg/mL, 88% recovery), with RSDs of repeatability and intermediate reproducibility below 10 and 15%, respectively for all the compounds. Conclusions and Highlights: To the best of best knowledge, this is the first report that allows for the characterization and quantification of vitamins A, E, and K and five carotenoids in <1 mL human milk.

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Barnokhon, Sattarova, Utanova Nazira i Makhmudova Aziza. "THE IMPORTANCE OF ENRICHMENT OF BAKERY PRODUCTS WITH VITAMINS AND MINERALS ON HUMAN HEALTH". International Journal of Advance Scientific Research 02, nr 04 (1.04.2022): 34–42. http://dx.doi.org/10.37547/ijasr-02-04-07.

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Graulet, Benoît. "Ruminant milk: A source of vitamins in human nutrition". Animal Frontiers 4, nr 2 (1.04.2014): 24–30. http://dx.doi.org/10.2527/af.2014-0011.

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Osman, Dina El-Rabie, Brandon Wee Siang Phon, Muhamad Noor Alfarizal Kamarudin, Stephen Navendran Ponnampalam, Ammu Kutty Radhakrishnan i Saatheeyavaane Bhuvanendran. "Biomarkers Regulated by Lipid-Soluble Vitamins in Glioblastoma". Nutrients 14, nr 14 (13.07.2022): 2873. http://dx.doi.org/10.3390/nu14142873.

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Glioblastoma (GBM), a highly lethal form of adult malignant gliomas with little clinical advancement, raises the need for alternative therapeutic approaches. Lipid-soluble vitamins have gained attention in malignant brain tumors owing to their pleiotropic properties and their anti-cancer potential have been reported in a number of human GBM cell lines. The aim of this paper is to systematically review and describe the roles of various biomarkers regulated by lipid-soluble vitamins, such as vitamins A, D, E, and K, in the pathophysiology of GBM. Briefly, research articles published between 2005 and 2021 were systematically searched and selected from five databases (Scopus, PubMed, Ovid MEDLINE, EMBASE via Ovid, and Web of Science) based on the study’s inclusion and exclusion criteria. In addition, a number of hand-searched research articles identified from Google Scholar were also included for the analysis. A total of 40 differentially expressed biomarkers were identified from the 19 eligible studies. The results from the analysis suggest that retinoids activate cell differentiation and suppress the biomarkers responsible for stemness in human GBM cells. Vitamin D appears to preferentially modulate several cell cycle biomarkers, while vitamin E derivatives seem to predominantly modulate biomarkers related to apoptosis. However, vitamin K1 did not appear to induce any significant changes to the Raf/MEK/ERK signaling or apoptotic pathways in human GBM cell lines. From the systematic analysis, 12 biomarkers were identified that may be of interest for further studies, as these were modulated by one or two of these lipid-soluble vitamins.

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Matasar, I. T., L. M. Petryschenko i A. V. Chernyshov. "Water-soluble vitamins: their physiological significance, role in life of humans and their content in the nutrition of the population suffered as a result of Chernobyl accident". One Health and Nutrition Problems of Ukraine 53, nr 2 (10.11.2020): 55–79. http://dx.doi.org/10.33273/2663-9726-2020-53-2-55-79.

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Aim of the Research. Generalization of information about the properties and history of discovery of water-soluble vitamins, their up-to-date classification, sources of their intake and daily consumption by people of different ages and for people affected by the Chernobyl accident and living in environmentally hazardous areas. The article describes the results and data of long-term studies of the actual consumption of water-soluble vitamins by the population living in radioactively contaminated areas as a result of the Chernobyl accident. Materials and Methods. The presented data of the academic literature on the history of discovery of vitamins reveal their main characteristics and significance for the functioning of the human body. The information about physiological needs and the main sources of vitamins intake are presented. Conclusions. The article is relevant for family doctors, hygienists, nutritiologists, nutritionists and others as a scientific information material on the prevention and correction of vitamin deficiency. Key Words: water-soluble vitamins, vitamin deficiency, daily intake of vitamins, population of environmentally fragile regions, Chernobyl accident.

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van Wijk, Nick, Carol J. Watkins, Mark Böhlke, Timothy J. Maher, Robert J. J. Hageman, Patrick J. G. H. Kamphuis, Laus M. Broersen i Richard J. Wurtman. "Plasma choline concentration varies with different dietary levels of vitamins B6, B12and folic acid in rats maintained on choline-adequate diets". British Journal of Nutrition 107, nr 10 (15.09.2011): 1408–12. http://dx.doi.org/10.1017/s0007114511004570.

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Choline is an important component of the human diet and is required for the endogenous synthesis of choline-containing phospholipids, acetylcholine and betaine. Choline can also be synthesisedde novoby the sequential methylation of phosphatidylethanolamine to phosphatidylcholine. Vitamins B6, B12and folate can enhance methylation capacity and therefore could influence choline availability not only by increasing endogenous choline synthesis but also by reducing choline utilisation. In the present experiment, we determined whether combined supplementation of these B vitamins affects plasma choline concentration in a rat model of mild B vitamin deficiency which shows moderate increases in plasma homocysteine. To this end, we measured plasma choline and homocysteine concentrations in rats that had consumed a B vitamin-poor diet for 4 weeks after which they were either continued on the B vitamin-poor diet or switched to a B vitamin-enriched diet for another 4 weeks. Both diets contained recommended amounts of choline. Rats receiving the B vitamin-enriched diet showed higher plasma choline and lower plasma homocysteine concentrations as compared to rats that were continued on the B vitamin-poor diet. These data underline the interdependence between dietary B vitamins and plasma choline concentration, possibly via the combined effects of the three B vitamins on methylation capacity.

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Crăciun, Isabela. "Comparative Study of Liposoluble Vitamins and Fatty Acids from Sea Buckthorn Oil, Wheat Germ Oil and Fish Oil". Acta Universitatis Cibiniensis. Series E: Food Technology 22, nr 2 (1.12.2018): 85–90. http://dx.doi.org/10.2478/aucft-2018-0016.

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Abstract An important role in human nutrition is played by fats, both of plant and animal origin. Fats are a category of foods rich in liposoluble vitamins and fatty acids. They are widely used in nutrition, in cosmetics, in the content of creams as well as in pharmaceutical products, in the form of dietary supplements, such as capsules with oils rich in fatty acids and the addition of liposoluble vitamins. The objective of this paper was to study the content in vitamins and fatty oils of two vegetable oils (wheat germ and sea buckthorn oils) and an animal oil (fish oil). The results show that these oils are rich in liposoluble vitamins, omega-3 fatty acids and omega-6 fatty acids. Hence, these oils can be used successfully in daily nutrition as substitutes for synthetic vitamins.

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Godswill, Awuchi Godswill, Igwe Victory Somtochukwu, Amagwula O. Ikechukwu i Echeta Chinelo Kate. "Health Benefits of Micronutrients (Vitamins and Minerals) and their Associated Deficiency Diseases: A Systematic Review". International Journal of Food Sciences 3, nr 1 (7.01.2020): 1–32. http://dx.doi.org/10.47604/ijf.1024.

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The research focused on the benefits of micronutrients (vitamins and minerals) and their associated deficiency diseases and health complications. Micronutrients are essential elements required by human and other organisms in varying quantities throughout life to coordinate a range of physiological functions for health maintenance. For human nutrition, micronutrients are required in amounts generally below 100 milligrams per day, while macronutrients are required in gram amounts daily. Vitamins and minerals are essential micronutrients. Essential nutrients cannot be synthesized in humans, either at all or may be in insufficient amounts, and therefore must be obtained by the diet. Vitamin C can be synthesized by some organisms but not by others; it is not a vitamin in the first instance but is in the second. In humans there are 13 vitamins: 9 water-soluble (8 B vitamins and vitamin C) and 4 fat-soluble (A, D, E, and K). Vitamins A and D can amass in the body, which may result in dangerous hypervitaminosis. Anti-vitamins inhibit the actions or absorption of vitamins; avidin inhibits biotin absorption, although it is deactivated by cooking; Pyrithiamine inhibits enzymes that use vitamin B1. The four key structural elements in human body (oxygen, hydrogen, carbon, and nitrogen) by weight, are often not included in the lists of major nutrient minerals (nitrogen is a "mineral" for plants, as it is often included in fertilizers). These four key elements compose around 96% of the weight of human body, and the major minerals (macrominerals) and minor minerals (trace elements) compose the remaining percent. The five major minerals in the the human body are calcium, phosphorus, potassium, sodium, and magnesium (macrominerals or macroelements). The trace elements with specific biochemical function in human body are iodine, sulfur, zinc, iron, chlorine, cobalt, copper, manganese, molybdenum, and selenium. Calcium makes up 920 to 1200 g of body weight (about 1.5% of body weight) of an adult, with 99% of it contained in the bones and teeth. Phosphorus occurs in amounts of around 2/3 of calcium, and makes up approximately 1% of an individual's body weight. The other macroelements (potassium, sodium, magnesium, chlorine, and sulfur) make up only around 0.85% of the body weight

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Mochulska, O. M., O. R. Boyarchuk, M. I. Kinash, T. O. Vorontsova i L. A. Volianska. "The effects of vitamins A, E, D, disorders of their metabolism and the assessment of level of vitamin security in children (literature review)". Modern pediatrics. Ukraine, nr 2(114) (27.03.2021): 58–66. http://dx.doi.org/10.15574/sp.2021.114.58.

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Vitamins are a group of biologically highly active, low molecular weight organic compounds of various chemical nature, which are practically not synthesized in the human body or are synthesized in insufficient quantities, mainly income with food, and are vital to ensure for the flow and regulation of metabolic processes in the body. Vitamins are micronutrients that are among the essential (essential) factors of nutrition, their content in food is small, usually in the range from 10 to 100 mg/100 g. Vitamins have an exceptional property — the ability to high biological activity in small doses, without being a source of energy or plastic material, act as biological catalysts for vital body functions. According to physicochemical properties and solubility, vitamins A, E, D belong to fat-soluble, are characterized by thermal stability, resistant to cysts and alkalis, their main characteristic is the ability to promote the assimilation of mаcro- and microelements. Vitamins A, E, D are needed at all stages of growth and development of the child's body, the processes of adaptation. The main types of vitamins metabolism disorders are vitamin deficiency, hypo-, hyper- and dysvitaminosis, polyvitaminosis. It is important to constantly monitor the sufficient content of each vitamins in the daily diet of children. The following methods of assessing vitamin supply are known: clinical, biochemical, calculation of vitamin content. Purpose — to increase knowledgment about the effects of vitamins A, E, D, their importance in metabolism, to analyze the main types of their metabolism disorders, to present possible methods for assessing the supply of vitamins in children. Conclusions. The child's body needs a constant supply of vitamins to maintain their amount at the required level. All vital processes take place in the body during the direct participation of vitamins. Future research in the field of the vitamins A, E, D effects will contribute to a better understanding of their role in ensuring the optimal functioning in a human body. Screening and elimination of vitamin A, E, D deficiency in children can not only improve health, but also help increase the life quality. No conflict of interest was declared by the authors. Key words: vitamins A, E, D, vitamin deficiency, hypovitaminosis, hypervitaminosis, dysvitaminosis, polyvitaminosis, children.

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Kulshrestha, Kalpana. "HORTICULTURAL CROPS VALUE ADDITION FOR NUTRITIONAL SECURITY". International Journal of Research -GRANTHAALAYAH 6, nr 10 (31.10.2018): 110–20. http://dx.doi.org/10.29121/granthaalayah.v6.i10.2018.1168.

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Nutritional well-being is a sustainable force for health and development of people and maximization of human genetic potential. From the beginning of human history, food has been considered as the major factor in maintaining well-being and health of individuals. Active ingredients in food which are effective in promoting human health include amino acids, fats dietary fiber, antioxidants, pigments, vitamins and minerals which are present in different food groups such as pulses, cereals, legumes, oilseeds, fruits and vegetables. Among all these food groups, fruits and vegetables play a significant role in human nutrition, especially as a source of vitamins, minerals and dietary fiber. The different fruits and vegetables like carrots, tomatoes potatoes, ginger, green leafy vegetables and the like are important protective foods because of their nutritional value and antioxidant properties. Value addition of such fruits and vegetables by formulation of different value-added products are an important source of nutritional security.

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Altemimi, Ammar B., Halgord Ali M. Farag, Tablo H. Salih, Farhang H. Awlqadr, Alaa Jabbar Abd Al-Manhel, Italo Rennan Sousa Vieira i Carlos Adam Conte-Junior. "Application of Nanoparticles in Human Nutrition: A Review". Nutrients 16, nr 5 (25.02.2024): 636. http://dx.doi.org/10.3390/nu16050636.

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Nanotechnology in human nutrition represents an innovative advance in increasing the bioavailability and efficiency of bioactive compounds. This work delves into the multifaceted dietary contributions of nanoparticles (NPs) and their utilization for improving nutrient absorption and ensuring food safety. NPs exhibit exceptional solubility, a significant surface-to-volume ratio, and diameters ranging from 1 to 100 nm, rendering them invaluable for applications such as tissue engineering and drug delivery, as well as elevating food quality. The encapsulation of vitamins, minerals, and antioxidants within NPs introduces an innovative approach to counteract nutritional instabilities and low solubility, promoting human health. Nanoencapsulation methods have included the production of nanocomposites, nanofibers, and nanoemulsions to benefit the delivery of bioactive food compounds. Nutrition-based nanotechnology and nanoceuticals are examined for their economic viability and potential to increase nutrient absorption. Although the advancement of nanotechnology in food demonstrates promising results, some limitations and concerns related to safety and regulation need to be widely discussed in future research. Thus, the potential of nanotechnology could open new paths for applications and significant advances in food, benefiting human nutrition.

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Swastawati, Fronthea, Putut Har Riyadi, Retno Ayu Kurniasih, Aninditya Artina Setiaputri i Defita Faridlotus Sholihah. "The Chemical Composition, Microbiology and Micronutrients Changes of Fresh Barracuda Fish and Smoked Barracuda Fish using Different Smoking Methods". Proceedings of The International Halal Science and Technology Conference 14, nr 1 (10.03.2022): 67–77. http://dx.doi.org/10.31098/ihsatec.v14i1.487.

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Fish play an essential role in human nutrition and ensure about 20% of protein intake for one-third of the world's population, especially in developing countries. Fish is consumed because of its nutritional benefits, such as protein, essential amino acids, fats, and micronutrients (vitamins and minerals). Micronutrients can prevent disease disorders due to micronutrient deficiencies. But behind its nutritional advantages, fish are very easy to spoil. Fish preservation and processing methods explore ways to stop or slow down spoilage. One method of preserving and processing fish that can be applied is smoking. This study aimed to evaluate the moisture content, total fat, heavy metals, vitamin A, and microbiology of fresh and smoked barracuda fish with different smoking methods, namely traditional smoking, and liquid smoke. Fresh barracuda fish is smoked using the traditional smoking method and liquid smoke. Fresh and smoked barracuda fish were then analyzed, including water content, total fat content, heavy metals (Cd, Hg, Sn, As), histamine, micronutrients (vitamins A and D), and microbial contamination. The levels of heavy metals, histamine, and microbial contamination have met the quality standard of smoked fish (SNI 2725: 2013). Vitamin A in fresh barracuda and smoked barracuda was < 15.85 mcg/100 g, while vitamin D was not detected in either fresh barracuda or smoked barracuda.

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Kumar, Akhilesh, Pringchinoramarak, Saket Mishra, Shashi Kant Ekka, Reena Kujur i Johnson Lakra. "A Review on the Nutritional Value of Some Leafy Vegetables used in India". Asian Journal of Biology 20, nr 1 (6.02.2024): 26–31. http://dx.doi.org/10.9734/ajob/2024/v20i1383.

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This review explores the nutritional profiles of leafy vegetables commonly used in Indian cuisine, emphasizing their significance in promoting human health and well-being. Leafy greens play a pivotal role in traditional Indian diets, contributing essential vitamins, minerals, and antioxidants. The low calorific value of leafy vegetables makes them ideal for human weight balance. The good nutrition profile of leafy vegetables are beneficial in reducing the risk of major diseases such as cardiovascular and cancer. Anti nutritional factors are chemical compounds in plant tissues, which deter the absorption of nutrients in humans. From all the findings it was suggested that consumption of leafy vegetables fulfills the nutrition reqiurements and avoid from malnutrition.

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BARTKOWICZ, JOANNA. "EDIBLE INSECTS AS A SOURCE OF NUTRIENTS THE HUMAN NUTRITION". sj-economics scientific journal 30, nr 3 (30.09.2018): 23–35. http://dx.doi.org/10.58246/sjeconomics.v30i3.83.

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The aim of the study is to analyze the state of knowledge about the nutrient content of edible insects and utilization for human consumption of the West. The article uses the latest reports published in scientific journals in the world. The paper presents the content of nutrients (proteins, lipids, vitamins, carbohydrates, minerals, fiber) in the analyzed edible insects. The results show a huge potential of edible insects. For many population of the world edible insects ate the primary source of nutrients and is not due to a lack of other food but because of the special taste and are treated almost as delights. Entomophagy (eating insects) is practiced mainly in the subtropical climate zone. In terms of protein, fatty acids, vitamins and minerals, edible insects surpass previously known to us foods and may become an unconventional and alternative source of food for Europe.

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Best, Cora M., Devon V. Riley, Thomas J. Laha, Hannah Pflaum, Leila R. Zelnick, Simon Hsu, Kenneth E. Thummel i in. "Vitamin D in human serum and adipose tissue after supplementation". American Journal of Clinical Nutrition 113, nr 1 (12.11.2020): 83–91. http://dx.doi.org/10.1093/ajcn/nqaa295.

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ABSTRACT Background Serum 25-hydroxyvitamin D [25(OH)D] concentration is an indicator of vitamin D exposure, but it is also influenced by clinical characteristics that affect 25(OH)D production and clearance. Vitamin D is the precursor to 25(OH)D but is analytically challenging to measure in biological specimens. Objectives We aimed to develop and validate a liquid chromatography–tandem mass spectrometry (LC-MS/MS) method for quantification of vitamins D3 and D2 in serum and to explore the potential of circulating vitamin D as a biomarker of exposure in supplementation trials. Methods The method was validated using guideline C62-A from the Clinical and Laboratory Standards Institute and was applied in 2 pilot clinical trials of oral vitamin D3 supplementation. Pilot study 1 included 22 adults randomly assigned to placebo or 2000 IU/d. Blood was collected at baseline, 1, 3, 6, and 12 mo. Pilot study 2 included 15 adults randomly assigned to 2000 or 4000 IU/d. Blood and subcutaneous (SUBQ) adipose tissue were collected at baseline and 3 mo. Results In study 1, mean change (baseline to 3 mo) in serum vitamin D3 was −0.1 ng/mL in the placebo group and 6.8 ng/mL in the 2000 IU/d group (absolute difference: 6.9; 95% CI: 4.5, 9.3 ng/mL). In study 2, mean change (baseline to 3 mo) in serum vitamin D3 was 10.4 ng/mL in the 2000 IU/d group and 22.2 ng/mL in the 4000 IU/d group (fold difference: 2.15; 95% CI: 1.40, 3.37). Serum and adipose tissue vitamin D3 concentrations were correlated, and the dose-response of vitamin D3 in adipose mirrored that in serum. Conclusions We validated a sensitive, robust, and high-throughput LC-MS/MS method to quantify vitamins D3 and D2 in serum. Serum and SUBQ adipose tissue vitamin D3 concentrations increased proportionally to dose with 3 mo of daily supplementation. These trials were registered at clinicaltrials.gov as NCT00552409 (pilot study 1) and NCT01477034 (pilot study 2).

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Vincenzetti, Silvia, Stefania Pucciarelli, Giuseppe Santini, Yulia Klimanova, Valeria Polzonetti i Paolo Polidori. "B-Vitamins Determination in Donkey Milk". Beverages 6, nr 3 (23.07.2020): 46. http://dx.doi.org/10.3390/beverages6030046.

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Background: Donkey milk is used in infant nutrition for the treatment of children affected by cow’s milk protein allergy, thanks to its hypo-allergenicity, mainly due to its protein profile, which is very close to that of human milk. Furthermore, donkey milk is characterized by the presence of a fair amount of bioactive proteins, that may have a positive impact on human health. Despite the presence of numerous articles that describe the chemical composition and nutraceutical properties of donkey milk, few works have been performed to determine its vitamin profile; therefore, the purpose of this work is to give further information on the B-vitamins profile of donkey milk. Methods: B-vitamins have been determined through a reversed-phase liquid chromatography analysis. Results: The results indicated that donkey milk (DM) contains thiamine 0.661 ± 0.26 μM, riboflavin 0.168 ± 0.04 μM, nicotinic acid 18.75 ± 1.92 μM, pyridoxine 5.38 ± 3.3 5μM, and folic acid 0.83 ± 0.08 μM. Conclusions: Donkey milk contains a high quantity of nicotinic acid, known for its lipid-lowering effect, and a good amount of vitamin B6 and folic acid, the latter very important for children’s growth. To notice, vitamin B6 has been determined for the first time in donkey milk.

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Lammi-Keefe, Carol J., i Robert G. Jensen. "Fat-Soluble Vitamins in Human Milk". Nutrition Reviews 42, nr 11 (27.04.2009): 365–71. http://dx.doi.org/10.1111/j.1753-4887.1984.tb02264.x.

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Carretero-Krug, Alejandra, Ana Montero-Bravo, Carmen Morais-Moreno, Ana M. Puga, Mª de Lourdes Samaniego-Vaesken, Teresa Partearroyo i Gregorio Varela-Moreiras. "Nutritional Status of Breastfeeding Mothers and Impact of Diet and Dietary Supplementation: A Narrative Review". Nutrients 16, nr 2 (19.01.2024): 301. http://dx.doi.org/10.3390/nu16020301.

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Adequate nutrition during breastfeeding is crucial for ensuring the good health of mothers and babies. Despite the high energy and nutrient demands of breastfeeding, lactating women are often vulnerable from a nutritional perspective. The nutritional focus during breastfeeding tends to be on the newborn, often neglecting the mother’s diet. Therefore, in the present narrative review, nutrient intakes were compared with the dietary reference values (DRVs) proposed by the European Food Safety Authority (EFSA) as well as by the World Health Organization/Food and Agriculture Organization (WHO/FAO). In the diets of lactating mothers, dietary inadequacies were observed in the intake of some vitamins, such as folic acid, vitamin B12, vitamin A, and vitamin D, and in the intake of certain minerals like calcium, iron, and iodine; polyunsaturated omega-3 fatty acid deficiencies, primarily in eicosapentaenoic acid and docosahexaenoic acid, were also observed. On the other hand, the debate on the necessity of supplementation during lactation continues; the need for nutritional supplementation during lactation depends on many factors, such us mothers’ eating habits. There seems to be a positive association between nutritional supplementation of the lactating mother and the concentration of certain nutrients in human milk. The present narrative review provides an update on the nutritional status (fatty acids and micronutrients) of breastfeeding mothers and the impact of diet and dietary supplementation on human milk composition.

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Hamilton, Iona M. J., William S. Gilmore, Iris F. F. Benzie, Clive W. Mulholland i J. J. Strain. "Interactions between vitamins C and E in human subjects". British Journal of Nutrition 84, nr 3 (wrzesień 2000): 261–67. http://dx.doi.org/10.1017/s0007114500001537.

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Despite convincingin vitroevidence, a vitamin C–E interaction has not been confirmedin vivo. This study was designed to examine the effects of supplementation with either vitamin C or E on their respective plasma concentrations, other antioxidants, lipids and some haemostatic variables. Fasting blood was collected before and after intervention from thirty healthy adults in a double-blinded crossover study. Baselines for measured variables were established after 2 weeks of placebo supplementation, followed by daily supplementation with 73·5 mgRRR-α-tocopherol acetate or 500 mg ascorbic acid, and placebo, for 6 weeks. A 2 month washout preceded supplement crossover. Mean values showed that plasma lipid standardised α-tocopherol increased with ascorbic acid supplementation: from 4·09 (SEM 0·51) TO 4·53 (sem 0·66) μmol/mmol total cholesterol plus triacylglycerol (P< 0·05), and plasma ascorbic acid increased from 62·8 (sem 14·9) to 101·3 (sem 22·2) μmol/l (P< 0·005). Supplementation with (RRR)-α-tocopherol acetate increased plasma α-tocopherol from 26·8 (sem 3·9) to 32·2 (sem 3·8) μmol/l (P< 0·05), and lipid-standardised α-tocopherol from 4·12 (sem 0·48) to 5·38 (sem 0·52) μmol/mmol (P< 0·001). Mean plasma ascorbic acid also increased with vitamin E supplementation, from 64·4 (sem 13·3) to 76·4 (sem 18·4) μmol/l (P< 0·05). Plasma ferric reducing (antioxidant) power and glutathione peroxidase (U/g haemoglobin) increased in both groups, while urate, total cholesterol and triacylglycerol levels decreased (P< 0·05 throughout). Results are supportive of anin vivointeraction between vitamins C and E.

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Brancaccio, Mariarita, Cristina Mennitti, Arturo Cesaro, Fabio Fimiani, Martina Vano, Biagio Gargiulo, Martina Caiazza i in. "The Biological Role of Vitamins in Athletes’ Muscle, Heart and Microbiota". International Journal of Environmental Research and Public Health 19, nr 3 (23.01.2022): 1249. http://dx.doi.org/10.3390/ijerph19031249.

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Physical activity, combined with adequate nutrition, is considered a protective factor against cardiovascular disease, musculoskeletal disorders, and intestinal dysbiosis. Achieving optimal performance requires a significantly high energy expenditure, which must be correctly supplied to avoid the occurrence of diseases such as muscle injuries, oxidative stress, and heart pathologies, and a decrease in physical performance during competition. Moreover, in sports activities, the replenishment of water, vitamins, and minerals consumed during training is essential for safeguarding athletes’ health. In this scenario, vitamins play a pivotal role in numerous metabolic reactions and some muscle biochemical adaptation processes induced by sports activity. Vitamins are introduced to the diet because the human body is unable to produce these micronutrients. The aim of this review is to highlight the fundamental role of vitamin supplementation in physical activity. Above all, we focus on the roles of vitamins A, B6, D, E, and K in the prevention and treatment of cardiovascular disorders, muscle injuries, and regulation of the microbiome.

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Penkert, Rhiannon R., Melissa Azul, Robert E. Sealy, Bart G. Jones, Jola Dowdy, Randall T. Hayden, Li Tang, A. Catharine Ross, Jane S. Hankins i Julia L. Hurwitz. "Hypothesis: Low Vitamin A and D Levels Worsen Clinical Outcomes When Children with Sickle Cell Disease Encounter Parvovirus B19". Nutrients 14, nr 16 (19.08.2022): 3415. http://dx.doi.org/10.3390/nu14163415.

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Human parvovirus B19 causes life-threatening anemia due to transient red cell aplasia (TRCA) in individuals with sickle cell disease (SCD). Children with SCD experiencing profound anemia during TRCA often require red blood cell transfusions and hospitalization. The prevalence of vitamin deficiencies in SCD is high and deficiencies are associated with respiratory and pain symptoms, but the effects of vitamins on acute infection with parvovirus B19 remain unclear. We performed a clinical study in which 20 SCD patients hospitalized with parvovirus B19 infections (Day 0) were monitored over a 120-day time course to query relationships between vitamins A and D and clinical outcomes. There were significant negative correlations between Day 0 vitamin levels and disease consequences (e.g., red blood cell transfusion requirements, inflammatory cytokines). There were significant positive correlations (i) between Day 0 vitamins and peak virus-specific antibodies in nasal wash, and (ii) between Day 0 virus-specific serum plus nasal wash antibodies and absolute reticulocyte counts. There was a significant negative correlation between Day 0 virus-specific serum antibodies and virus loads. To explain the results, we propose circular and complex mechanisms. Low baseline vitamin levels may weaken virus-specific immune responses to permit virus amplification and reticulocyte loss; consequent damage may further reduce vitamin levels and virus-specific immunity. While the complex benefits of vitamins are not fully understood, we propose that maintenance of replete vitamin A and D levels in children with SCD will serve as prophylaxis against parvovirus B19-induced TRCA complications.

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Viña, Jose, Mari-Carmen Gomez-Cabrera i Consuelo Borras. "Fostering antioxidant defences: up-regulation of antioxidant genes or antioxidant supplementation?" British Journal of Nutrition 98, S1 (październik 2007): S36—S40. http://dx.doi.org/10.1017/s0007114507839596.

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Vitamins have traditionally been considered as food components that are required in the normal diet to prevent deficiencies. However, a newer concept of the function of vitamins in nutrition has taken them beyond simply prevention of deficiency symptoms. This concept considers that many vitamins, when taken in relatively larges doses, have important functions beyond preventing deficiencies. Linus Pauling was instrumental in putting forward this concept, particularly for vitamin C. Thus, relatively high intakes of vitamins, and in particular vitamins C and E which are antioxidants, are considered to be healthy for the human population. This may be true in some special situations such as, for instance, the prevention of Alzheimer's disease progression. However, recent epidemiological evidence has not supported the claim that antioxidant vitamins increase well-being and prolong life span. In fact, vitamin supplementation may be even detrimental and reduce life span. A new concept that we would like to put forward is that nutrients up-regulate the endogenous antioxidant defences. This is particularly true in the case of phytoestrogens for example, which bind to oestrogen receptors and eventually up-regulate the expression of antioxidant genes. In this review we discuss the pros and cons of antioxidant vitamin supplementation and also the possibility that the ingestion of some nutrients may be very effective in increasing antioxidant defences by up-regulating the activity of antioxidant enzymes which are normally present in the cell.

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Zharova, Yulia Sergeevna, Victoria Andreevna Dudareva, Maksim Leonidovich Maksimov, Irina Glebovna Dyadikova i Malika Anarbekovna Ismailova. "Features of nutrition and vitamin and mineral prevention in young people during the Covid-19 pandemic". Vrač skoroj pomoŝi (Emergency Doctor), nr 10 (1.10.2020): 49–61. http://dx.doi.org/10.33920/med-02-2010-04.

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Purpose of researh was making recommendations on diet for students in self-isolation mode, taking into account the analysis of their nutrition. Methods. A representative group was formed by random sampling. The study involved 40 students (23 women and 17 men) of Rostov State Medical University, average age 22.5 years ± 1 year (group 1). To create the database, we used the human nutritional analysis program, version 1.2.4., Registered by the Russian Agency for Patents and Trademarks 02/09/04 No. 2004610397 GUNII Nutrition RAMS. Comparison of the results was carried out with a similar group outside the conditions of self-isolation caused by the pandemic covid-19 (control group). Results. In the group of women surveyed, the energy value of the diet was 1832.77 kcal. The daily amount of incoming protein is 66.6 g, fat — 97.3 g (45 % more than the recommended amount), carbohydrates — 167.87 g (42 % lower than normal). The content of trace elements: sodium — 124 % more than normal, phosphorus — 43 %. At the same time, the content of other trace elements and vitamins is less than necessary: calcium — by 18 %, magnesium — by 39 %, vitamin B1 — by 55 %, vitamin B2 — by 35 %, niacin — by 45 %. In the group of men surveyed, the energy value of the diet was 1848.24 kcal; the amount of protein consumed — 66.93 g, fat — 97.7 g (20 % higher than normal), carbohydrates — 169.6 g (53 % less than the recommended amount). The content of trace elements: sodium — 123 % more than normal, phosphorus — 46 %. There is a lack of intake of many trace elements and vitamins: calcium — 15 % less than recommended, magnesium — 38 %, vitamin B1–54 %, vitamin B2–32 %, niacin — 45 %. Conclusion. In general, we can conclude that the nutrition of the students surveyed does not correspond to the current situation. Although the energy value of the daily diet is optimal, the ratio of macro- and micronutrients is violated. Recommendations are given to reduce the consumption of foods containing fats and phosphorus, in favor of foods containing complex carbohydrates, as well as vitamins B1, B2, niacin, magnesium and calcium. The need to minimize the consumption of salt, sugar, saturated and trans isomers of fatty acids is noted. It is also recommended in conditions of self-isolation to add specialized and fortified foods, as well as vitamin-mineral complexes, to the diet.

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Brown, B., K. R. Garvin, B. G. Hughes, M. D. Standing, K. L. O'Neill i B. K. Murray. "Induction of Apoptic Features in Human Colon Cancer Cells After Exposure to Specific Vitamin Combinations". Microscopy and Microanalysis 6, S2 (sierpień 2000): 892–93. http://dx.doi.org/10.1017/s1431927600036953.

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Proper nutrition and vitamin consumption have long been associated with lower risks for many human cancers. Data from recent studies have suggested that exposure to antioxidant vitamins and vitamin combinations can induce genetic programed cell death, apoptosis, in human cancer cells. ‘“3 In this study, we report on the induction of apoptosis in HT-29 human colon adenocarcinoma cells after exposure to low doses of 13- c/s-retinoic acid (RA) and vitamin E succinate (VES). Induction of apoptosis was seen only in cancerous colon cells and not in normal human colon cells when exposed to RA and VES in combination, but not when exposed to either vitamin alone.Cultures of HT-29 cells were seeded in 6 well plates at 10,000 cells/well and grown at 37°C, 5% C02 in RPMI 1640 medium supplemented with 10% fetal bovine serum.

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Ofoedu, Chigozie E., Jude O. Iwouno, Ebelechukwu O. Ofoedu, Chika C. Ogueke, Victory S. Igwe, Ijeoma M. Agunwah, Arinze F. Ofoedum i in. "Revisiting food-sourced vitamins for consumer diet and health needs: a perspective review, from vitamin classification, metabolic functions, absorption, utilization, to balancing nutritional requirements". PeerJ 9 (1.09.2021): e11940. http://dx.doi.org/10.7717/peerj.11940.

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The significant attention gained by food-sourced vitamins has provided insights into numerous current researches; for instance, the potential reversal of epigenetic age using a diet and lifestyle intervention, the balance between food and dietary supplements in the general population, the role of diet and food intake in age-related macular degeneration, and the association of dietary supplement use, nutrient intake and mortality among adults. As relevant literature about food-sourced vitamin increases, continuous synthesis is warranted. To supplement existing information, this perspective review discussed food-sourced vitamins for consumer diet and health needs, scoping from vitamin absorption, metabolic functions, utilization, to balancing nutritional requirements. Relevant literatures were identified through a search of databases like Google Scholar, Web of Science, the Interscience Online Library, ScienceDirect, and PubMed. We demonstrated that vitamins whether from plant- and animal-based sources are prerequisites for the metabolic functions of the human body. The fat- and water-soluble classification of vitamins remains consistent with their respective absorption and dissolution potentials, underpinned by numerous physiological functions. Vitamins, largely absorbed in the small intestine, have their bioavailability dependent on the food composition, its associated interactions, as well as alignment with their metabolic functions, which involves antioxidants, coenzymes, electron acceptor/donor, and hormones. Moreover, vitamin deficiencies, in every form, pose a serious threat to human health. Vitamin toxicities remain rare, but can still occur mainly from supplementation, although it appears much less in water-soluble vitamins of which some excesses get readily removed by the human body, different from the fat-soluble ones that are stored in tissues and organs. Besides discussions of absorption, transport, and cellular uptake of vitamins, this perspective review also included approaches to meeting vitamin requirements and therapeutic strategies against micronutrient deficiency and COVID-19. We have also attempted on how to strike the balance between food-sourced vitamins and dietary supplements.

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