Artykuły w czasopismach: „Tuberculosis”

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Das, Anirban, Sibes Kumar Das, Abhijit Mandal i Arup Kumar Halder. "Cerebral tuberculoma as a manifestation of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis". Journal of Neurosciences in Rural Practice 03, nr 03 (wrzesień 2012): 350–54. http://dx.doi.org/10.4103/0976-3147.102622.

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ABSTRACTExpansion of cerebral tuberculomas or their new appearance as a manifestation of paradoxical reaction in patients under antituberculous chemotherapy is well documented. Distinguishing paradoxical reaction from disease progression or treatment failure is an important issue in tuberculosis management. Five cases of cerebral tuberculomas are reported here as manifestations of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis on antituberculous treatment. Case 1 and 2 had tuberculous meningitis, Case 3 had miliary tuberculosis, Case 4 had miliary tuberculosis and destructive vertebral lesions, and Case 5 had pulmonary tuberculosis. Continuation of antituberculous drugs and addition of steroids led to full recovery of all patients.

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N., Rajeshwari, i Savitha A. "Tuberculosis: a great masquerader". International Journal of Contemporary Pediatrics 7, nr 7 (24.06.2020): 1651. http://dx.doi.org/10.18203/2349-3291.ijcp20202636.

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Central nervous system tuberculosis caused by Mycobacterium tuberculosis is the most severe form of tuberculosis, accounting for 1% of all TB cases. Intracranial tuberculosis can present as Tuberculous meningitis, Tuberculous encephalopathy, Tuberculous vasculitis, CNS tuberculomas and Tuberculous brain abscess. Here authors present a case of a 10-year-old girl who presented with insidious onset of early morning vomiting, excessive sleepiness with classical neuroimaging findings of intracranial tuberculosis. Authors emphasise that intracranial tuberculoma should be considered in the differential diagnosis of any intracranial space-occupying lesion with or without pulmonary involvement.

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Trianes, Juwy. "EDUCATION ON THE IMPORTANCE OF BTA EXAMINATION TO DETECT TUBERCULOSIS IN IMPROVING HEALTHY LIFE IN COMMUNITY". Khidmah 4, nr 1 (7.06.2022): 426–32. http://dx.doi.org/10.52523/khidmah.v4i1.372.

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Pemeriksaan BTA sangat penting dilakukan untuk membantu masyarakat menurunkan angka kejadian penyakit tuberculossis, kegiatan pemeriksaan untuk mendeteksi penyakit tuberculossis kepada masyarakat umumnya untuk memberikan pengetahuan tentang pentingnya mencegah penyakit tuerculossis. Penyuluhan pemeriksaan BTA untuk mendeteksi penyakit tuberculossis dilakukan di Desa Kertabayang dengan metode edukasi melalui media leaflet. Pada hasil penyuluhan pentingnya pemeriksaan BTA untuk mendeteksi penyakit tuberculossis di Desa Kertabayang telah mengetahui gejala-gejala penyakit tuberculosis sehingga jika terdapat gejala penyakit tuberculosis untuk dilakukan pemeriksaan BTA. Pemeriksaan BTA sangat berpengaruh untuk menurunkan angka kejadian terjadinya penyakit tubberculossis.

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Kaur, Harveen, Dilbag Singh, Amritpal Kaur, N. C. Kajal i Mukul Sharma. "Central nervous system Tuberculomas in a patient with disseminated multi-drug resistant tuberculosis; A case report". International Journal of Current Research in Medical Sciences 7, nr 1 (30.01.2021): 1–5. http://dx.doi.org/10.22192/ijcrms.2021.07.01.001.

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Tuberculosis (TB) is one of the leading causes of death worldwide, particularly in low- and middle-income countries. Although Mycobacterium tuberculosis can involve any organ, most commonly the lung, central nervous system (CNS) tuberculosis is the most devastating form of the disease. Tuberculoma is the most common parenchymal lesion in CNS tuberculosis which could be found in any portion of the intracranial space. The global rates and numbers of drug resistant TB are rising. With increasing globalization, the spread of drug-resistant strains of TB has become a mounting global public health concern. We present a case of 27-year-old male with disseminated multi-drug resistant (MDR) TB who presented with neurological symptoms and multiple CNS Tuberculomas. The patient was started on regimen for Multi-drug resistant tuberculosis (MDR-TB), which allowed the serial resolution of intracranial tuberculomas. Keywords: Tuberculosis (TB), Multi-drug resistant (MDR) TB, Central nervous system (CNS) TB, Tuberculoma, MRI brain

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Zlata, Hajric Zidan, Pasic Amela i Selimovic Selma. "Silent Brain Tuberculomas with Acute Miliary Tuberculosis in 13-Year Old Girl - Case Report". International Journal of Health Sciences and Research 11, nr 6 (10.06.2021): 145–47. http://dx.doi.org/10.52403/ijhsr.20210621.

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We describe iron deficiency and silent intracranial tuberculomas with pulmonary miliary tuberculosis in 13-year old girl which can be rare seen, particularly in immunocompetent children. She presented as respiratory infection with lack of menstrual bleeding. She didn’t receive BCG vaccination. Chest roentgenogram showed miliary pattern while MRI of brain revealed parenchymal tuberculomas. Empirical 4 antitubercular drug treatments were initiated. Control showed a decrease in size and number of brain tuberculomas. Silent brain tuberculomas with miliary tuberculosis could be rare seen, particularly in immunocompetent children. It remains an open question whether the irregular menstrual bleeding and iron deficiency was associated with the drop of her immunity and increased risk for military tuberculosis. Key words: BCG vaccination, irregular menstrual bleeding, MRI of endocranium.

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Tellez Bolaños, Vianey Guadalupe, Alejandra Lizbeth Salinas Atriano, Karla Daniela Salgado Guizar, Louis Fernando Robles Fernandez, Francisco Javier Pedraza Murillo i Roberto Camarena Álvarez. "Cerebral tuberculomas: manifestation of extrapulmonary tuberculosis in an immunocompromised patient. A case report". Iberoamerican Journal of Medicine 5, nr 4 (16.09.2023): 181–85. http://dx.doi.org/10.53986/ibjm.2023.0030.

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Tuberculosis (Tb) is, currently, the deadliest infectious disease and is caused by organisms of the Mycobacterium tuberculosis complex; the most common clinical manifestation is pulmonary involvement; however, it can also manifest as extrapulmonary affection in immunocompromised patients, especially in patients with human immunodeficiency virus (HIV) chronic infection up to 20% of the cases, despite being on adequate antiretroviral therapy. Within the extrapulmonary manifestations, affection of the central nervous system by hematogenous dissemination occurs in up to 5%, however, the finding of tuberculomas, which is a form of central nervous system involvement, is rare and an important cause in secondary hydrocephalus in these patients. We present the case of a male patient with a history of HIV infection and meningeal tuberculosis, who presented dysfunction of his ventriculoperitoneal shunt and in the imaging study multiple tuberculomas were found, a cerebrospinal fluid study was performed where multi-resistant tuberculosis (MDR) was documented, therefore despite adequate management of Tb, tuberculomas developed.

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Vidal, José E., Adrián V. Hernández, Augusto C. Penalva de Oliveira, Alexandre de Leite Souza, Geraldine Madalosso, Paula R. Marques da Silva i R. Dauar. "Cerebral tuberculomas in AIDS patients: a forgotten diagnosis?" Arquivos de Neuro-Psiquiatria 62, nr 3b (wrzesień 2004): 793–96. http://dx.doi.org/10.1590/s0004-282x2004000500010.

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The human immunodeficiency virus (HIV) infection epidemics increased the prevalence, multi-drug resistance and disseminated forms of tuberculosis. The central nervous system (CNS) tuberculosis has high mortality and morbidity, and it is usually divided into diffuse (meningitis) and localized (tuberculoma and abscess) forms. We report three cases of cerebral tuberculomas in AIDS patients: one with definitive diagnosis, confirmed with histopathology, and two with probable diagnosis, based on clinical information, radiological images, Mycobaterium tuberculosis isolation out of the CNS and adequate response to antituberculous treatment. Further, we discuss diagnostic, therapeutic and prognostic issues of tuberculomas, with emphasis in the distinction from cerebral tuberculous abscesses. Despite of their infrequent presentation, tuberculomas should be considered in the differential diagnosis of cerebral expansive lesions in patients with AIDS.

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Sarwar, SM, i Masroor Rahman. "Isolated tuberculous thyroiditis". Bangladesh Journal of Otorhinolaryngology 22, nr 1 (22.01.2020): 62–64. http://dx.doi.org/10.3329/bjo.v22i1.45087.

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Tuberculosis is a widespread infectious disease caused by various strains of Mycobacteria, usually Mycobacterium tuberculosis1.Tuberculosis generally affects the lungs ,but can also affect other parts of the body. Tuberculosis of the thyroid gland is an extremely rare condition. We report a case of a 35 years old female patient with isolated Tuberculous Thyroiditis presented as diffuse tenderness and pain in lower part of anterior neck with no visible neck swelling. Fine needle aspiration cytology (FNAC) from the thyroid gland revealed caseatingepitheloid granulomas consistent with tuberculosis. Bangladesh J Otorhinolaryngol; April 2016; 22(1): 62-64

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B H, Parameshwar Keerthi, Anil Kumar Sakalecha, Varun S, Shivaprasad G. Savagave i Raveesha Raveesha. "An interesting case of disseminated tuberculoma of brain and spinal cord". JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 9, nr 2 (15.06.2019): 50–52. http://dx.doi.org/10.58739/jcbs/v09i2.1.

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Tuberculosis is a public health problem worldwide causing significant morbidity and mortality. Manifestations of tuberculo-sis are widely classified as pulmonary and extra pulmonary. Tuberculoma is one of the CNS manifestations, which on imag-ing shows ring enhancing lesions. Although intracranial tuberculomas are common, spinal tuberculomas are rare and consti-tute only 2% of CNS tuberculomas. We present a case of both intra-axial and spinal tuberculoma in the same patient. Keywords: Tuberculosis, CNS, Tuberculoma, Ring enhancing lesion, MRI

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Smirnov, G. A. "Variants of destructive pulmonary tuberculosis and the necessity of their differentiated treatment". Kazan medical journal 75, nr 6 (15.11.1994): 408–12. http://dx.doi.org/10.17816/kazmj100065.

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The results of observations of 1196 patients being first ill with destructive pulmonary tuberculosis are analysed. By quantitative and qualitative characteristics of destructive pulmonary process, 5 categories are revealed differing widely in rate and terms of the decay cavities close and results by the action of chemotherapy. pulmonary tuberculosis with minimum destruction, bounded destructive, tuberculomas with decay and fibrocavernous pulmonary tuberculosis. The necessity to develop the differenciated therapy methods of destructive pulmonary tuberculosis depending on its quantitative and qualitative characteristics is stressed.

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Adiego, M. I., J. Millán, J. Royo, L. Dománguez, M. A. Castellote, J. I. Alfonso i H. Vallés. "Unusual association of secondary tonsillar and cerebral tuberculosis". Journal of Laryngology & Otology 108, nr 4 (kwiecień 1994): 348–49. http://dx.doi.org/10.1017/s0022215100126738.

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AbstractThe patient was a 50-year-old alcoholic man with a left palatine tonsillar ulcer. Histopathological and bacteriological studies established the diagnosis of tonsillar tuberculosis with asymptomatic advanced pulmonary tuberculosis and multiple cerebral supra- and infratentorial tuberculomas previously unnoticed.

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Álvarez-Jaramillo, Juliana, Ana María Ortiz-Zableh, Pamela Tarazona-Jiménez i Alfredo Ortíz-Azuero. "Hidrocele como manifestación inicial de tuberculosis genitourinaria y miliar". MedUNAB 22, nr 1 (30.07.2019): 71–78. http://dx.doi.org/10.29375/01237047.3534.

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Introducción. La tuberculosis es una enfermedad infectocontagiosa que puede afectar cualquier órgano del cuerpo, incluyendo el sistema genitourinario, representando el 33.7-45.5 % de las tuberculosis extrapulmonares. El objetivo de este trabajo es reportar el caso de un paciente con hidrocele como manifestación inicial de tuberculosis genitourinaria y miliar, enfermedad que no se sospechaba. Presentación del caso. Paciente masculino previamente sano, que consulta a urgencias por orquialgia e hidrocele bilateral, con secreción purulenta por escroto, requiriendo manejo antibiótico intravenoso e hidrocelectomía derecha, con hallazgos intraoperatorios de engrosamiento del epidídimo derecho, y drenaje de material caseoso y purulento. Se realizó epididimectomía ipsilateral, se solicitaron pruebas de detección de bacilos tuberculosos en espécimen y derivado proteico purificado, que fueron positivas. En el postoperatorio presentó sintomatología respiratoria; paraclínicos evidenciaron compromiso pulmonar, pleural y de la vía urinaria por bacilos tuberculosos. Se inicia manejo antituberculoso con evolución satisfactoria. Discusión. El genitourinario es considerado el segundo sistema con mayor afectación de tuberculosis extrapulmonar. El órgano más afectado es el riñón (en un 80 % con respecto a los demás) y el órgano genital es el epidídimo (22 - 55 %). Debe sospecharse en pacientes con síntomas urinarios crónicos sin causa aparente. Se asocia a una alta tasa de morbimortalidad por infertilidad y falla renal. Conclusiones. A pesar de su sintomatología inespecífica y de tratarse de una entidad poco sospechada, la tuberculosis genitourinaria debe descartarse al existir tuberculosis pulmonar. Su diagnóstico y tratamiento oportuno serán de gran importancia para evitar complicaciones secundarias.

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Rodríguez Cajiao, Felipe. "Tuberculoma intracerebral en gestante inmunocompetente". Revista de la Facultad de Ciencias Médicas (Quito) 43, nr 2 (1.12.2018): 175–82. http://dx.doi.org/10.29166/rfcmq.v43i2.2837.

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la tuberculosis causada por la bacteria Mycobacterium tuberculosis, se encuentra entre las 10 primeras causas de mortalidad a nivel mundial; la presentación extrapulmonar se produce por siembra vía hematógena o linfática desde un foco primario, correspondiendo a la afectación de sistema nervioso central el 5% de infecciones por TB y se presenta con menor frecuencia en personas inmunocompetentes. Las formas de tuberculosis de SNC son meningitis, tuberculosis espinal y tuberculomas que corresponden al 1% de infecciones por TB. El tratamiento se basa en la terapia antifímica, reservando el manejo neuroquirúrgico para puntuales indicaciones como deterioro neurológico, hidrocefalia o mala respuesta al tratamiento farmacológico.

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Rodríguez Cajiao, Felipe. "Tuberculoma intracerebral en gestante inmunocompetente". Revista de la Facultad de Ciencias Médicas (Quito) 43, nr 2 (1.12.2018): 175–82. http://dx.doi.org/10.29166/rfcmq.v43i2.2837.

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la tuberculosis causada por la bacteria Mycobacterium tuberculosis, se encuentra entre las 10 primeras causas de mortalidad a nivel mundial; la presentación extrapulmonar se produce por siembra vía hematógena o linfática desde un foco primario, correspondiendo a la afectación de sistema nervioso central el 5% de infecciones por TB y se presenta con menor frecuencia en personas inmunocompetentes. Las formas de tuberculosis de SNC son meningitis, tuberculosis espinal y tuberculomas que corresponden al 1% de infecciones por TB. El tratamiento se basa en la terapia antifímica, reservando el manejo neuroquirúrgico para puntuales indicaciones como deterioro neurológico, hidrocefalia o mala respuesta al tratamiento farmacológico.

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Hwang, Sook Min, Ji Young Rho, Seung Min Yoo, Hae Kyoung Jung i Sang Ho Cho. "Atypical pleural tuberculosis presenting as an isolated pleural tuberculoma". Acta Radiologica 53, nr 1 (luty 2012): 49–52. http://dx.doi.org/10.1258/ar.2011.110384.

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Pleural tuberculosis is the most common extrapulmonary manifestation of tuberculosis, and is generally characterized by an effusion. The effusion is usually unilateral and residual pleural thickening or calcification is also observed in some cases. Manifestations of multiple pleural tuberculomas without associated effusion and history of tuberculosis or antituberculous therapy are rare and an isolated pleural tuberculoma is exceedingly rare. Herein, we report the first documented case of an isolated pleural tuberculoma, diagnosed by chest CT and pathological findings. Although rare, an isolated pleural tuberculoma should be added to the differential diagnosis of focal nodular pleural tumors, particularly in areas of high tuberculosis prevalence.

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Santos, Rose Mary Corrêa, Mauricio Morishi Ogusku, José de Moraes Miranda, Maria Cristina dos-Santos i Julia Ignez Salem. "Avaliação da reação em cadeia da polimerase no diagnóstico da tuberculose pulmonar em pacientes indígenas e não indígenas". Jornal Brasileiro de Pneumologia 32, nr 3 (czerwiec 2006): 234–40. http://dx.doi.org/10.1590/s1806-37132006000300010.

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OBJETIVO: Avaliar a acurácia dos métodos bacteriológicos e da reação em cadeia da polimerase com oligonucleotídeos específicos para a IS6110 do complexo Mycobacterium tuberculosis, em amostras de escarro de indígenas e não indígenas. MÉTODOS: Analisaram-se 214 amostras de escarro (154 de indígenas e 60 de não indígenas) quanto à acurácia da baciloscopia direta e pós-concentração, cultivo e reação em cadeia da polimerase. RESULTADOS: Ambos os métodos baciloscópicos, quando comparados com o cultivo ou a reação em cadeia da polimerase foram de baixa sensibilidade. A especificidade variou de 91% a 100%, sendo a baciloscopia pós-concentração menos específica. Nas amostras indígenas constataram-se três vezes mais isolamentos de micobactérias não tuberculosas do que nas não indígenas. Resultados da reação em cadeia da polimerase aparentemente falsos-positivos e negativos foram encontrados com maior freqüência na população indígena. CONCLUSÃO: Baciloscopias positivas para bacilos álcool-acidorresistentes com isolamento de micobactérias não tuberculosas e reação em cadeia da polimerase positiva estabelecem as hipóteses de: existência na Amazônia de espécies de micobactérias não tuberculosas com regiões do DNA homólogas à IS6110 ou ainda que possuam a IS6110, até então só descrita no complexo M. tuberculosis; impossibilidade de isolamento do M. tuberculosis pelo crescimento mais rápido de micobactérias não tuberculosas presentes nas amostras de escarro, por colonização da orofaringe ou da lesão tuberculosa; presença de DNA de M. tuberculosis devida a antecedente de tuberculose. A ausência de positividade em resultados bacteriológicos com reação em cadeia da polimerase positiva sugere questões técnicas inerentes aos métodos bacteriológicos ou precedentes de tuberculose.

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Tripathi, Anuj Kumar, Zahwa Rizwan, Shagufta Tahir Mufti i Gyanendra Prakash. "Intramedullary tuberculoma of thoracic spine: A rare location of an endemic disease". IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain 8, nr 1 (15.04.2022): 15–18. http://dx.doi.org/10.18231/j.ijashnb.2022.005.

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Tuberculosis (TB) is endemic in India, alone contributing for two thirds of total cases worldwide. Spinal tuberculosis accounts for 1-2% of all cases of tuberculosis. However, spinal intramedullary tuberculoma occurs in as few as 2 out of 1000 cases of tuberculosis involving central nervous system. This may present in form of meningitis, tubercular spondylitis, arachnoididtis or tuberculomas mostly. The most common site of involvement is found to be the thoracic region of spine affecting relatively younger age groups and often seen in association with extraspinal tuberculosis disease. The source of intramedullary tuberculosis is mostly hematogenous spread from a site of primary TB elsewhere in the body which is usually the lungs.Due to rarity of the disease misdiagnosis is frequent.Magnetic Resonance Imaging is the investigation of choice and histopathological examination and culture are confirmatory methods for diagnosis of tuberculosis.Microsurgical resection is better option for rapidly progressing intramedullary tuberculosis cases. Here we report a rare case of isolated spinal intramedullary tuberculoma of thoracic spinal region.

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Akritidis, Nikolaos, Eftichia Galiatsou, John Kakadellis, Konstantinos Dimas i Konstantinos Paparounas. "Brain Tuberculomas Due to Miliary Tuberculosis". Southern Medical Journal 98, nr 1 (styczeń 2005): 111–13. http://dx.doi.org/10.1097/01.smj.0000149409.38256.14.

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Bruyn, G. W. "Tuberculous meningitis: Tuberculomas and spinal tuberculosis". Journal of the Neurological Sciences 86, nr 2-3 (wrzesień 1988): 361. http://dx.doi.org/10.1016/0022-510x(88)90110-4.

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Biyani, Dr Garima. "Congenital Tuberculosis -A Rare Form of Tuberculosis". Journal of Medical Science And clinical Research 04, nr 12 (20.12.2016): 14762–65. http://dx.doi.org/10.18535/jmscr/v4i12.73.

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Kemer Aktaş, Zeynep, i Tuğçe Tural Kara. "Bağışıklanmamış İki Kardeşte Farklı Tüberküloz Klinikleri: Kaviter Akciğer Tüberkülozu ve Tüberküloz Plörezisi". Journal of Pediatric Infection 16, nr 4 (14.12.2022): 280–84. http://dx.doi.org/10.5578/ced.20229626.

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Kiady, Ravahatra, Rakotondrabe Iantsotiana Davidson, Rasoafaranirina Marie Odette, Tiaray Harison Michel, Nandimbiniaina Anjara i Rakotoson Joëlson Lovaniaina. "Profil De Résistance Des Mycobabcterium Tuberculosis Des Malades En Retraitement Dans La Région De Haute Matsiatra, Madagascar". European Scientific Journal, ESJ 13, nr 18 (30.06.2017): 465. http://dx.doi.org/10.19044/esj.2017.v13n18p465.

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Introduction: Relapse, failure and defaulted treatment are a risk factor for Mycobacterium tuberculosis resistance to anti-tuberculosis. The objective of our study is to determine the resistance profile of Mycobacterium tuberculosis of patients in retreatment at the Haute Matriatra area. Method: This is a retrospective, descriptive study carried out on the basis of the data contained in the register of the Haute Matsiatra Regional Tuberculosis Laboratory of the University Hospital of Fianarantsoa, from May 2014 to December 2016 (31 months). We included patients with retreatment in the study. Results: We found 138 patients in retreatment. The average age was 39.32 years with a sex ratio of 2.11. Resistance to Rifampicin and Isoniazid was respectively 2.17% and 2.82%, The prevalence of multidrug-resistant tuberculosis was 0.72%. Conclusion: Tuberculosi resistance, monoresistance or multidrug resistance is a reality in the region of Haute Matsiatra with a prevalence that is still low, reflecting the effectiveness of the tuberculosis control program. However, monoresistances require special attention and monitoring to avoid the emergence of multidrug resistant strains.

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Asriyani, Sri, Erlin Syahril i Nelly. "Multiple organ tuberculomas in infant". Journal of Clinical Imaging Science 12 (3.06.2022): 30. http://dx.doi.org/10.25259/jcis_212_2021.

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Tuberculoma is a space-occupying lesion resulting from the containment of the inflammatory process in metastatic tuberculosis, which most commonly occur in the brain and lungs. This form of tuberculosis is commonly found in adults, but rarely seen in children. Here we reported a case of an infant with multiple organ tuberculomas. The patient had unspecific signs and symptoms. There were also multiple cervical lymph nodes enlargement and weakness in both lower limbs and right hand. Chest radiograph showed a left pulmonary mass which was further evaluated by thorax CT imaging and revealed pulmonary tuberculoma, mediastinal lymphadenopathies, and pneumonia. Cervical ultrasound showed multiple cervical lymphadenites and brain MRI with contrast showed multiple intracranial tuberculomas with focal meningitis. A microscopic examination from gastric lavage sampling revealed a positive acid-fast bacillus smear and a biopsy of a lump in the neck demonstrated a picture of chronic granulomatous lymphadenitis that supports tuberculosis infection. Through this case, we emphasize the importance of the various appearance of pulmonary and extrapulmonary tuberculosis in infants.

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Muro, Denys Janet Gonzales, Gerardo Campos Siccha i Raulins Ramírez Gutiérrez. "Características clínicas de la tuberculosis mamaria en pacientes atendidas en un servicio de ginecoobstetricia, 2002- 2011". Revista Peruana de Ginecología y Obstetricia 59, nr 2 (29.07.2013): 107–13. http://dx.doi.org/10.31403/rpgo.v59i5.

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Objetivos: Determinar las características clínicas de la tuberculosis mamaria en pacientes atendidas en un Servicio de Gineco-Obstetricia. Diseño: Estudio observacional, descriptivo, retrospectivo. Institución: Servicio de Gineco-Obstetricia, Hospital Nacional Docente Madre Niño San Bartolomé, Lima, Perú. Participantes:Pacientes con tuberculosis mamaria. Intervenciones: Se revisó 40 historias clínicas de pacientes que tuvieron el diagnostico clínico de tuberculosis mamaria, durante el periodo 2002 a 2011. Principales medidas de resultados: Características clínicas de mujeres con tuberculosis mamaria. Resultados: Se encontró 29 casos de tuberculosis mamaria, correspondiendo a 2,9% de incidencia anual. La mayoría procedía del Rímac, San Martin de Porres y Cercado de Lima. La edad promedio fue 32,8 ± 8,2 años de edad y con promedio de 2,3 ± 1,2 gestaciones; 51,7% tenía sobrepeso y 13,8% obesidad. El tiempo de enfermedad fue dos a cuatro meses en 70%. El 72,4% presentó tumor mamario, 31% nodularidad dolorosa y 13,8% linfoadenopatía axilar. Un 10,7% se encontraba gestando o dando de lactar al momento del diagnóstico; 10,3% de los casos estaba asociado a tuberculosis pulmonar, 7,1% a tuberculosis extrapulmonar y 14,3% tuvo contacto con pacientes tuberculosos. El 68% recibió tratamiento antituberculoso. Solo 31% de las pacientes fue sometida a intervención quirúrgica. La respuesta al tratamiento en 96,6% de los casos fue buena. Conclusiones: De las pacientes con tuberculosis mamaria atendidas, una de cada seis estuvo asociada a tuberculosis pulmonar y extrapulmonar. Los procedimientos más utilizados para el diagnóstico fueron la biopsia, mamografía, ecografía mamaria y radiografía de tórax. Se requiere tener en cuenta la posibilidad de tuberculosis mamaria en gestantes y madres lactantes. Palabras clave: Tuberculosis mamaria, mastitis crónica, características clínicas.

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Gami Vinit Patel, Payal. "Chest Wall Tuberculosis - An Extension of Mediastinal Tuberculosis". International Journal of Science and Research (IJSR) 12, nr 1 (5.01.2023): 269–70. http://dx.doi.org/10.21275/sr23105232822.

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González Olaechea, Max. "Neumonía hiperplásica tuberculosa". Anales de la Facultad de Medicina 4 (19.11.2014): 81. http://dx.doi.org/10.15381/anales.v4i0.10669.

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La tuberculosis inflamatoria dice PONCET, es aquella forma de tuberculosis en la cual la toxina bacilar más o menos atenuada produce en los tejidos las reacciones comunes de la inflamación; está pues desprovista de la especificidad anatómica : folículos tuberculosos, células gigantes, etc. considerados antes como indispensables para manifestar el origen bacilar de una lesión. Ella ataca bajo los aspectos clínicos más variados, los más inesperados, todos los tejidos, todos los aparatos, todos los órganos.

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Nisa Ul husna, Nisaulhusna, Suharmadji Suharmadji, Wulan Sari, Agus Alamsyah i Zulmeriza Rasyid. "Faktor Risiko Kejadian Tuberculosis Paru Di Wilayah Kerja Puskesmas Rumbai Kecamatan Rumbai Pesisir Tahun 2019". Jurnal Kesehatan Komunitas 6, nr 2 (2.10.2020): 211–17. http://dx.doi.org/10.25311/keskom.vol6.iss2.410.

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Tuberculosis (TB Paru) adalah penyakit menular yang di sebabkan oleh Mycobacterium Tuberculosis, yang dapat menyerang paru dan organ lainnya. Puskesmas Rumbai Kecamatan Rumbai Pesisir mengalami peningkatan kasus tuberculosis paru setiap tahun dengan jumlah pada tahun 2018-2019 terdapat 78 kasus (35,8%). Tujuan penelitian ini untuk mengetahui risiko faktor status gizi, perilaku, riwayat kontak, dan kepadatan hunian terhadap kejadian tuberculosis paru. Jenis penelitian ini menggunakaan metode kuantitatif obsevasional dengan desain case control. Lokasi penelitian dilakukan di Wilayah Kerja Puskesmas Rumbai Kecamatan Rumbai Pesisir pada bulan Juni-Juli 2019. Populasi penelitian ini sebagian penderita TB Paru dan yang bukan penderita TB Paru yang terdaftar dalam catatan rekam medis Puskesmas Rumbai. Responden dalam penelitian ini yaitu sebanyak 90 responden dilakukan dengan cara wawancara dan observasi kepada 45 responden kasus tuberculosis paru dan 45 responden kontrol yang bukan penderita tuberculoisis paru yang dipilih menggunakan teknik systematic random salmpling. Pengumpulan data menggunakan kuesioner dan cross cek. Analisis yang digunakan adalah analisis univariat dan bivariat dengan uji chi-square dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa status gizi (p-value = 0,000, OR = 25,107 CI 95% = 8,268 – 76,245), riwayat kontak (p-value = 0,000, OR = 13,000 CI 95% = 4,505 – 37,510) dan perilaku (p-value = 0,009, OR = 3,532 CI 95% = 1,440 – 8,665) merupakan faktor risiko kejadian tuberculosis paru. Disarankan kepada puskesmas untuk meningkatkan informasi terkait tentang pecegahan terjadinya kejadian tuberculosis paru dan melakukan surveilans aktif untuk memutus mata rantai penularan penyakit tuberculosis paru.

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Migone, Oscar, i Boris Blank. "La tuberculosis hematógena en el estado grávido puerperal control obstétrico y tisiológico en 15 casos". Revista Peruana de Ginecología y Obstetricia 11, nr 2 (9.07.2015): 201–5. http://dx.doi.org/10.31403/rpgo.v11i1265.

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La tuberculosis hematógena se presenta en porcentajes más altos en los embarazadas que en las no gestantes; 10% de los casos de tuberculosis en las primeras y 5 % en estas últimas. Este estudio fue realizado en dos grupos de 150 y 200 pacientes respectivamente, en condiciones similares para ambos. Se han controlado 15 pacientes que presentaron formas hematógenos de tuberculosis pulmonar, en forma sistemático y permanente, durante y después del estado grávidopuerperal, por un período no menor de 4 años en total, con un tratamiento que implico: internación permanente y régimen higiénico-dietético-medicamentoso adecuado. Se ha observado en estos pacientes una patología obstétrica similar a la de las tuberculosas no hematógenas muy avanzadas: interrupción prematura del embarazo, anemias verdaderas; hipodinomias en el trabajo de parto; subinvolución uterino en el puerperio; etc., en porcentajes más elevados que lo habitual. Pero no se han observado hemorragias genitales en ningún caso, hecho muy llamativo por la circunstancia de ser frecuentes en el alumbramiento de las tuberculosas no hematógenas. Otras características obstétricas no se dosificaron por su escaso número o gran variación.

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Laskar, Nourjahan, Md Akram Hossain, Jannatul Fardows i Mominur Rahman. "GeneXpert MTB/RIF Assay for Rapid Identification of Mycobacterium Tuberculosis and Rifampicin Resistance Directly from Sputum Sample". Journal of Enam Medical College 7, nr 2 (4.06.2017): 86–89. http://dx.doi.org/10.3329/jemc.v7i2.32653.

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Background: The World Health Organization has endorsed the use of molecular methods for the detection of tuberculosis (TB) and drug resistant TB as a rapid method. In Bangladesh, the Xpert MTB/RIF assay has been implemented into reference laboratories for diagnosis of TB and also MDR TB.Objective: Drug resistant tuberculosis has long been a common problem prevailing in our country. The present study focused on the rapid identification of Mycobacterium tuberculosis as well as drug resistance.Materials and Methods: Sputum samples from a total of 107 cases, assumed as multi-drug resistance tuberculosis, were studied through GeneXpert assay.Results: Out of 107 cases, 91 (85.05%) were detected having M. tuberculosis ? 64 (59.81%) were rifampicin sensitive and 27 (25.23%) were rifampicin resistant. The sensitivity and specificity of the GeneXpert are 87.64% and 75% respectively.Conclusion: GeneXpert assay can be considered for the rapid diagnosis of drug resistant tuberculosis.J Enam Med Col 2017; 7(2): 86-89

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Elfarissi, Mohammed Alamine, Mohamed Dahamou, Younes Dehneh, Mohammed Lhamlili, Mohamed Khoulali, Noureddine Oulali i Faycal Moufid. "Pediatric sellar-suprasellar tuberculosis: A case report and review of the literature". Surgical Neurology International 14 (27.10.2023): 379. http://dx.doi.org/10.25259/sni_476_2023.

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Background: Pediatric sellar-suprasellar tuberculosis is a rare form of tuberculosis that affects the pituitary gland and surrounding areas in the brain. It can be difficult to diagnose based on clinical and radiological signs alone, as they can be similar to other pituitary masses. A combination of biological, hormonal, and imaging examinations can aid in making an accurate diagnosis. It is important to consider tuberculosis in the differential diagnosis of sellar-suprasellar masses in the pediatric population, especially in areas with a high prevalence of tuberculosis. Case Description: A 17-year-old male with no history of illness showed up with a series of symptoms, including headaches and vision problems. A sellar-suprasellar lesion was seen on imaging, along with several minor lesions. The diagnosis of tuberculosis meningitis with cerebral and pituitary tuberculoma was made after cerebrospinal fluid analysis revealed the presence of tuberculosis. Treatment with anti-tuberculosis drugs led to clinical improvement and lesion resolution. Conclusion: Children’s sellar tuberculomas can be difficult to diagnose since they resemble other pituitary tumors. It is essential to take them into account in the differential diagnosis, especially in regions with a high incidence of tuberculosis. Long-term chemotherapy is the recommended course of treatment, and monthly follow-up visits are necessary to check hormone levels and evaluate whether a permanent hormone replacement is necessary.

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Ceylan, Erkan, i Mehmet Gencer. "Miliary Tuberculosis Associated with Multiple Intracranial Tuberculomas". Tohoku Journal of Experimental Medicine 205, nr 4 (2005): 367–70. http://dx.doi.org/10.1620/tjem.205.367.

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Mansour, Ahmad M., i Robert Haymond. "Choroidal tuberculomas without evidence of extraocular tuberculosis". Graefe's Archive for Clinical and Experimental Ophthalmology 228, nr 4 (1990): 382–83. http://dx.doi.org/10.1007/bf00920066.

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Momen, Abdul Basit Ibne, Furial Quraishi Twinkle i Firoz Ahmed Quraishi. "Inferior Venacaval Thrombosis in Active Tuberculosis". Anwer Khan Modern Medical College Journal 11, nr 2 (10.08.2020): 137–39. http://dx.doi.org/10.3329/akmmcj.v11i2.62761.

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Approximately one third of the world's population is infected with Mycobacterium tuberculosis. TuberculosisJ has several mechanisms that induce a hypercoagulable state and can lead to thromboembolic complications. A variety of factors have been postulated to predispose patients with tuberculosis to venous thrombosis that include local stasis due to venous compression by lymph nodes and relative immobility caused by respiratory, alteration in coagulation factors and reactive thrombocytosis. Only a few case reports showing similar findings. We present a case, man of 26 years old, who presented deep vein thrombus of inferior vena cava from its origin extending up to the entrance of the liver revealed signal changes on L2 vertebrae and CT guided FNAC was negative for malignancy but suggestive of tuberculosis. There might be a possible association between deep venous thrombosis and use of Rifampicin but this does not contraindicate the use of Rifampicin but these patient may need close monitoring. AKMMC J 2020; 11(2) : 137-139

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Hammi, Sanae, Naima Zimed, Khalid Bouti i Jamal Eddine Bourkadi. "Paradoxical reactions during Antituberculosis therapy - A single-center prospective analysis". International Journal of Medicine and Surgery 2, nr 2 (26.12.2015): 32–35. http://dx.doi.org/10.15342/ijms.v2i2.75.

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[1] Hawkey CR, Yap T, Pereira J, Moore DA, Davidson RN, Pasvol G, et al. Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis. Clinical infectious diseases. 2005;40(9):1368-71. [2] Breton G. Syndrome inflammatoire de reconstitution immune (IRIS) associé à la tuberculose. Journal des Anti-infectieux. 2012;14(4):180-5. [3] Cheng V, Ho P, Lee R, Chan K, Woo P, Lau S, et al. Clinical spectrum of paradoxical deterioration during antituberculosis therapy in non-HIV-infected patients. European Journal of Clinical Microbiology and Infectious Diseases. 2002;21(11):803-9. [4] Al-Majed S. Study of paradoxical response to chemotherapy in tuberculous pleural effusion. Respiratory medicine. 1996;90(4):211-4. [5] Campbell I, Dyson A. Lymph node tuberculosis: a comparison of various methods of treatment. Tubercle. 1977;58(4):171-9. [6] Memish Z, Mah M, Mahmood SA, Bannatyne R, Khan M. Clinico‐diagnostic experience with tuberculous lymphadenitis in Saudi Arabia. Clinical microbiology and infection. 2000;6(3):137-41. [7] Choremis C, Padiatellis C, ZOU MLD, Yannakos D. Transitory exacerbation of fever and roentgenographic findings during treatment of tuberculosis in children. American review of tuberculosis. 1955;72(4):527. [8] Orlovic D, Smego J. Paradoxical tuberculous reactions in HIV-infected patients. The International Journal of Tuberculosis and Lung Disease. 2001;5(4):370-5. [9] Park I-S, Son D, Lee C, Park JE, Lee J-S, Cheong M-H, et al. Severe paradoxical reaction requiring tracheostomy in a human immunodeficiency virus (HIV)-negative patient with cervical lymph node tuberculosis. Yonsei medical journal. 2008;49(5):853-6. [10] Martinez V, Bricaire F. Réactions paradoxales. La Presse Médicale. 2006;35(1):1753-6. [11] Narita M, Ashkin D, Hollender ES, Pitchenik AE. Paradoxical worsening of tuberculosis following antiretroviral therapy in patients with AIDS. American journal of respiratory and critical care medicine. 1998;158(1):157-61. [12] Vidal CG, Garau J. Systemic steroid treatment of paradoxical upgrading reaction in patients with lymph node tuberculosis. Clinical infectious diseases. 2005;41(6):915-6. [13] Rakotoarivelo R, Vandenhende M-A, Michaux C, Morlat P, Bonnet F. Réactions paradoxales sous traitement antituberculeux chez des personnes non infectées par le VIH: quatre nouvelles observations et revue de la littérature. La Revue de médecine interne. 2013;34(4):202-8. [14] Cheng V, Yam W, Woo P, Lau S, Hung I, Wong S, et al. Risk factors for development of paradoxical response during antituberculosis therapy in HIV-negative patients. European Journal of Clinical Microbiology and Infectious Diseases. 2003;22(10):597-602. [15] Rao GP, Nadh BR, Hemaratnan A, Srinivas T, Reddy PK. Paradoxical progression of tuberculous lesions during chemotherapy of central nervous system tuberculosis: report of four cases. Journal of neurosurgery. 1995;83(2):359-62. [16] Fontanilla J-M, Barnes A, Von Reyn CF. Current diagnosis and management of peripheral tuberculous lymphadenitis. Clinical Infectious Diseases. 2011;53(6):555-62. [17] Guinchard A-C, Pasche P. Lymphadénite tuberculeuse cervicale et réaction paradoxale: diagnostic et traitement. ORL. 2012;356(34):1860-5. [18] Colebunders R, John L, Huyst V, Kambugu A, Scano F, Lynen L. Syndrome inflammatoire de reconstitution immunitaire de la tuberculose dans les pays à ressources limitées. Int J Tuberc Lung Dis. 2006;10(9):946-53. [19] Malone J, Paparello S, Rickman L, Wagner K, Monahan B, Oldfield E. Intracranial tuberculoma developing during therapy for tuberculous meningitis. Western Journal of Medicine. 1990;152(2):188. [20] Valdez LM, Schwab P, Okhuysen PC, Rakita RM. Paradoxical subcutaneous tuberculous abscess. Clinical infectious diseases. 1997;24(4):734-. [21] Bouchez B, Arnott G, Colover J. Paradoxical expansion of intracranial tuberculomas during chemotherapy. The Lancet. 1984;324(8400):470-1. [22] [Recommendations of the French Language Pneumology Society for tuberculosis management in France: consensus conference. Nice, France, 23 January 2004]. Revue des maladies respiratoires. 2004;21(3 Pt 2):S3-104. [23] Rabar D, Issartel B, Petiot P, Boibieux A, Chidiac C, Peyramond D. Tuberculomes et méningoradiculite tuberculeuse d’évolution paradoxale sous traitement. La Presse Médicale. 2005;34(1):32-4. [24] Chambers S, Record C, Hendrickse W, Rudge P, Smith H. Paradoxical expansion of intracranial tuberculomas during chemotherapy. The Lancet. 1984;324(8396):181-4. [25] Safdar A, Brown AE, Kraus DH, Malkin M. Paradoxical reaction syndrome complicating aural infection due to Mycobacterium tuberculosis during therapy. Clinical infectious diseases. 2000;30(3):625-7. [26] Hejazi N, Hassler W. Multiple intracranial tuberculomas with atypical response to tuberculostatic chemotherapy: literature review and a case report. Infection. 1997;25(4):233-9.

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Cristea, Cristiana, Cornel Popescu, Mihaela Voicu, Stela Mereuţă, Maria Nica, Cristiana Oprea i Emanoil Ceauşu. "Disseminated tuberculosis in a pregnant HIV negative woman with 12 weeks of pregnancy obtained through in vitro fertilization". Romanian Journal of Infectious Diseases 18, nr 4 (31.12.2015): 164–70. http://dx.doi.org/10.37897/rjid.2015.4.8.

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Information on the outcome of extrapulmonary tuberculosis in pregnant women is limited. We present particular clinical and outcome aspects in a pregnant HIV negative woman (with pregnancy after in vitro fertilization) with tuberculosis at multiple extrapulmonary sites. In addition, we will describe the paradoxical reaction with appearance of cerebral tuberculomas after 7 months of antituberculous therapy initiation, most probably in the context of a immune reconstitution inflammatory syndrome (IRIS).

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Liu, E., P. Kakodkar, H. Pan, A. Zhou, C. Wan, RN Auer, S. Sanche, A. Vitali i J. Radic. "P.075 Pediatric intracranial tuberculoma: case report and review of literature". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 50, s2 (czerwiec 2023): S79. http://dx.doi.org/10.1017/cjn.2023.177.

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Background: Tuberculosis is an airborne disease caused by Mycobacterium Tuberculosis. Intracranial tuberculoma is a rare complication of extrapulmonary tuberculosis due to hematogenous spread to subpial and subependymal regions. Intracranial tuberculoma can occur with or without meningitis. Methods: A 3-year-old male who recently emigrated from Sudan presented to the emergency department with right-sided seizures lasting 30 minutes which were aborted with levetiracetam and midazolam. CT head revealed a multilobulated left supratentorial mass, with solid and cystic components measuring 8.0 x 4.8 x 6.5 cm. The patient had successful surgical resection of the mass which was positive for Mycobacterium Tuberculosis. He was started on rifampin, isoniazid, pyrazinamide, ethambutol, and fluoroquinolone and discharged home in stable condition. Results: Literature review on pediatric intracranial tuberculoma was performed which included 48 studies (n=49). The mean age was 8.8 ± 5.4 years with slight female predilection (59%). Predominant solitary tuberculomas (63%) were preferentially managed with both surgical resection and antitubercular therapy (ATT) compared to multifocal tuberculomas that were preferentially managed with ATT. Conclusions: Intracranial tuberculoma is a rare but treatable cause of space-occupying lesions in children. Clinicians should maintain high-level of suspicion in patients from endemic regions and involve infectious disease service early in patient’s care.

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Kakar, Iftikhar Ali, Nasir Azim, Abdul Baqi, Yasir Arfat, Ayesha Abbas, Khalid Shahab i Muhammmad Idrees. "Frequency of Tuberculosis in Cervical Lymphadenopathy at Tertiary Care Hospital". Pakistan Journal of Medical and Health Sciences 16, nr 12 (31.12.2022): 394–96. http://dx.doi.org/10.53350/pjmhs20221612394.

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Background: Tuberculosis is a major public health concern, and it is the most prevalent cause of infectious disease that infects the lymphoid tissue of the body. Clinicians have a diagnostic challenge when treating chronic enlargement of cervical lymph node since it may be a sign of a more serious condition. Objective: To assess the frequency of tuberculosis in cervical lymphadenopathy at tertiary care hospital Methodology: This descriptive study was undertaken at the Department of Pulmonology, Fatima Jinnah Institute of Chest Diseases and Sheikh Khalifa Bin Zayyed Al Nahyan Medical Complex Quetta from October 2021 to October 2022. A complete physical examination was performed after taking a detailed medical history from each patient. A pre-designed proforma was used for the collection of all required data. SPSS version 23 was used to analyze all of the data. Results: In the current study, 140 patients were enrolled. There were 84 (60%) male participants while female participants were 56 (40%). The overall frequency of tuberculosis in patients with cervical lymphadenopathy was 98 (70%). Conclusion: Our study concludes that tuberculosis is the prevalent cause of cervical lymphadenopathy. All the patients with cervical lymphadenopathy must be diagnosed for tuberculosis. Keywords: Frequency; tuberculosi; csservical lymphadenopathy

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Matvyeyeva, S. L., i O. S. Shevchenko. "Thyroid tuberculosis: rare location or rarely diagnosed? Literature review". Tuberculosis, Lung Diseases, HIV Infection, nr 3 (27.09.2022): 78–84. http://dx.doi.org/10.30978/tb-2022-3-78.

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Objective — to study of the frequency, clinical picture, diagnosis and treatment of tuberculosis of thyroid gland. Materials and methods. Analyses the date of the world experience and own observations. Results and discussion. Thyroid tuberculosis is a less frequent localization of this disease. Currently, most authors believe that thyroid tuberculosis is diagnosed in 0.1–1 % of all known cases of tuberculosis. Clinical observations have found that the thyroid gland is more often involved in the tuberculous process with a generalized miliary process, and, as previously thought, in this case there are no clinical signs of damage to the thyroid gland. A variable clinical presentation of thyroid tuberculosis was demonstrated. It is usually presented with local symptoms associated with diffuse enlargement of the thyroid gland. It is difficult to estimate the quantity of diagnosed cases due to insufficient knowledge of the doctors about this pathology and difficulties of tuberculosis etiology diagnosis. Tuberculous etiology must be ruled out in all lesions on the median surface of the neck. Fine-needle biopsy can help to confirm the diagnosis of thyroid tuberculosis, but the final diagnosis is possible only with histological or cytological studies. The diagnosis of thyroid tuberculosis requires the use of most of all the methods used in the diagnosis of tuberculosis: from the simplest (such as X-ray or Mantoux test (with 2 international units of tuberculin) methods to modern rapid molecule-genetic tests XpertMTB/Rif that detect specific fragments of MTB DNA in serum or plasma). Ultrasound and computer tomography also help the clearing of the diagnosis. Surgical treatment in combination with antimycobacterial chemotherapy is effective. Conclusions. Further investigations are needed to understand the definition, diagnosis and treatment of tuberculosis among other diseases of thyroid.

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Álvarez, Adriana. "La experiencia de ser un 'niño débil y enfermo' lejos de su hogar: el caso del Asilo Marítimo, Mar del Plata (1893-1920)". História, Ciências, Saúde-Manguinhos 17, nr 1 (marzec 2010): 13–31. http://dx.doi.org/10.1590/s0104-59702010000100002.

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Este trabajo tiene como objetivo analizar la vida cotidiana de los 'niños tuberculosos', provenientes de la ciudad de Buenos Aires, que fueron internados en el Hospital Marítimo, ubicado a 400km de la metrópolis, en la localidad marítima de Mar del Plata. En 1893, surgió la idea en la Sociedad de Beneficencia de la Capital Federal de fundar un hospital y el Asilo Marítimo destinado a niños enfermos de tuberculosis ósea en general, a niños débiles y convalecientes y también al tratamiento de pacientes con tuberculosis extra-pulmonar. En este artículo, se pretende avanzar en la comprensión de dos problemáticas vinculadas entre sí: por un lado las características de la ingerencia institucionalizada de la Sociedad de Beneficencia y por el otro, la experiencia que estos niños tuberculosos vivieron en ese ámbito.

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Ortiz Faucheux, Ricardo Ernesto, Cristina Hermelinda Llosa Rodríguez i Yanela Elízabeth Paredes Espejo. "Adherencia terapéutica en pacientes con tuberculosis en el centro de salud Ciudad Nueva, Tacna – 2016". Revista Médica Basadrina 11, nr 2 (9.05.2019): 26–29. http://dx.doi.org/10.33326/26176068.2017.2.620.

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INTRODUCCION: La tuberculosis se perpetúa como un grave problema de salud pública en el Perú y nuestra región a pesar de contar con programas enérgicos para combarla. El diagnóstico temprano y la adherencia al tratamiento son factores clave para el programa de prevención y control de la tuberculosis; sin embargo, la falta de adherencia terapéutica es común con las consecuentes tasas bajas de curación. El objetivo fue determinar la adherencia terapéutica en pacientes con tuberculosis en Centro de Salud Ciudad Nueva de Tacna. MATERIAL Y MÉTODOS: Estudio básico, descriptivo. Se trabajó con el total de la población, 23 pacientes tuberculosos atendidos en el Centro de Salud Ciudad Nueva. Para la evaluación se utilizó el Test de Morisky Levine. Se utilizó estadísticas descriptivas. RESULTADOS: las edades de los pacientes atendidos en este programa fluctúan entre 18 a 29 años de los cuales más del 52% no respondieron positivamente a la evaluación. CONCLUSION: La mayoría de pacientes con tuberculosis atendidos en el Centro de Salud Ciudad Nueva en el año 2016, presentan mala adherencia al tratamiento.

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Li, Duo, Pingxin Lv, Yan Lv, Daqing Ma i Jigang Yang. "Magnetic resonance imaging characteristics and treatment aspects of ventricular tuberculosis in adult patients". Acta Radiologica 58, nr 1 (20.07.2016): 91–97. http://dx.doi.org/10.1177/0284185116633913.

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Background Ventricular involvement in neurotuberculosis is rare. The literature regarding the characteristics of magnetic resonance imaging (MRI) in ventricular tuberculosis is very limited. Purpose To describe MRI characteristics of ventricular tuberculosis and discuss the medical treatment along with the clinical outcome. Material and Methods Ten patients (6 men, 4 women; average age, 39 years) were diagnosed with ventricular tuberculosis during a period of 3 years. Four patients had the history of pulmonary/pleural tuberculosis. The clinical and MRI features of these patients were reviewed retrospectively. Results On a brain MRI, three patients showed ependymitis associated with contrast enhancement of the ependymal lining of the ventricular walls. One patient had choroid plexitis associated with prominent swollen and marked enhancement of the choroid plexus. One patient had intraventricular tuberculoma associated with an intraventricular nodule. Two patients had both ependymitis and choroid plexitis. Three patients had both intraventricular tuberculoma and choroid plexitis. Four patients had hydrocephalus. All patients underwent intrathecal injection of isoniazid and dexamethasone combined with multidrug anti-tuberculosis treatment. All patients had a good clinical recovery, except for one who developed hemi-paralysis due to cerebral infarction. On the repeated MRI of eight patients after therapy, all lesions disappeared or decreased in size, apart from in one patient who showed ventricular separation. Conclusion MRI characteristics of ventricular tuberculosis included ependymal enhancement, swelling, and enhancement of the choroid plexus and intraventricular tuberculomas. Intrathecal injection of isoniazid and dexamethasone along with multidrug chemotherapy showed good efficacy in ventricular tuberculosis.

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Saxena, Suvinay, Palak Patel, Drushi Patel i Ankur Shah. "Tuberculosis or Not Tuberculosis: Temporal Evolution of Patellar Tuberculosis". Indian Journal of Musculoskeletal Radiology 2 (29.06.2020): 62–65. http://dx.doi.org/10.25259/ijmsr_5_20-19.

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Patellar tuberculosis (TB) is an uncommon occurrence and has been sparsely reported in the literature. Imaging plays a key role in its diagnosis, as clinical symptoms vary and are often unspecific. We present two cases of isolated patellar tuberculosis, its classical imaging features, and follow-up serial imaging.

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Druzhinin, V. G., E. D. Baranova, P. S. Demenkov, Ju V. Zakharova, M. B. Lavryashina, A. V. Larionov, L. V. Matskova, A. V. Shabaldin i T. V. Pyanzova. "Composition of bacterial microbiome in sputum of patients with localized forms of pulmonary tuberculosis". PULMONOLOGIYA 33, nr 5 (6.09.2023): 645–56. http://dx.doi.org/10.18093/0869-0189-2023-33-5-645-656.

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Recent studies have shown that the respiratory bacterial microbiome has an impact on the development of pulmonary tuberculosis. Changes in the composition of the microbiome have been associated with the pathogenesis of Mycobacterium tuberculosis infection, response to therapy, and clinical outcomes of the disease. To date, the composition of the respiratory microbiome has not been studied in patients with localized forms of pulmonary tuberculosis. Methods. In the present study, the taxonomic composition of the sputum microbiome of 14 patients with localized forms of pulmonary tuberculosis (tuberculomas) and 14 healthy donors in the comparison group was analyzed by sequencing (NGS) of the V3 – V4 region of the bacterial gene encoding 16S rRNA. Results. The sputum microbiomes of the patients and the control group did not have significant differences in the species richness index (Shannon). However, the patients showed a decrease in the uniformity index, another parameter of alpha diversity. Bacterial community structures (beta diversity) did not differ significantly between patients with localized forms of tuberculosis and healthy subjects. In patients with limited forms of tuberculosis, contrary to the decrease in the content of representatives of the phyla Fusobacteria, TM7, Tenericutes, Spirochaetes, and SR1, and of the genera Dialister, Mycoplasma, and Filifactor in the sputum, no clear dominance of any bacterial taxon was observed. Conclusion. Certain alpha and beta diversity parameters that characterize the sputum microbiome of patients with localized forms of pulmonary tuberculosis need to be confirmed in independent large-scale studies to further understand the role of the sputum microbiota in the development of localized forms of pulmonary tuberculosis. Determination of Prevotella titers in the sputum of these patients holds promise for the diagnosis of localized forms of pulmonary tuberculosis and the search for their genomic markers.

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Rahayu, Devi Agustini, Keyshia N. Yazid i Bermansyah Burhan. "Pulmonary tuberculoma, to resect or not to resect: a systematic review". Intisari Sains Medis 14, nr 3 (29.12.2023): 1254–58. http://dx.doi.org/10.15562/ism.v14i3.1900.

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Introduction: Pulmonary tuberculomas usually present as a solitary pulmonary nodule. Pulmonary tuberculoma is difficult to differentiate from lung cancer. The treatment should follow the multiple disciplinary teams. Method: This systematic review aims to summarize the effectiveness of pulmonary tuberculoma treatment, including the response to anti-tuberculosis treatment or surgical resection. PubMed, Wiley, Cochrane, ProQuest, and ScienceDirect were searched for any design study that showed the cure rate of pulmonary tuberculoma treatment, with surgical resection or the used of anti-tuberculosis treatment. Result: Four studies were identified and analyzed from 288 initial articles. Data were then extracted from the studies and summarized descriptively. Two hundred eighty-eight articles were screened, and four studies were identified and eventually selected. The cure rate of pulmonary tuberculoma increased in patients with surgical procedures compared with medical treatment (only anti-tuberculosis treatment). Pulmonary tuberculoma responds poorly to anti-tuberculosis treatment and often requires long-term treatment. Conclusion: The treatment of tuberculoma with surgical resection works effectively, with better short- and long-term effects for tuberculoma. Surgical resection was effective in increasing the cure rate of pulmonary tuberculoma. Pulmonary resection in combination with post-operative anti-tuberculosis treatment results in excellent cure rate.

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STOREY, Christine, i Júlia Ignez SALEM. "LAY USE OF AMAZONIAN PLANTS FOR THE TREATMENT OF TUBERCULOSIS". Acta Amazonica 27, nr 3 (wrzesień 1997): 175–82. http://dx.doi.org/10.1590/1809-43921997273182.

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The Brazilian State of Amazonas has a high incidence of Tuberculosis, 91.4 in 10,000 habitants (SESAU, 1994) and resistant strains of Mycobacterium tuberculosis are frequently being found in the region (SALEM et.al, 1990). These problems have been associated with side effects caused by the antibiotics used to treat Tuberculosis, which have in rum been associated with treatment non-compliance (PATTISAPU, 1984). To resolve this problem a cost effective alternative treatment for Tuberculosis with few or no side effects, needs to be found. Amazonas has an abundance of plants, many of which are used by the lay population for medicinal purposes. A survey was carried out in five towns of the region, interviewing patients receiving treatment for Tuberculosis, to find out whether and which plants have been used to treat Tuberculosis. Results showed that the majority of patients in the sample had used medicinal plants before or after diagnosis of Tuberculoses. Thirteen different plants were recorded for this purpose. Chenopodium ambrosioides L, popularly known as Mastruz, was the most commonly used, followed by Caesalpinia ferrea Mart. Jucá and Spilanthes acmella DC. Jambu. This study concentrates on Mastruz as it was used more frequently than the other medicinal plants. No significant effects on baciloscopy test results were found when Mastruz was used before diagnosis. ln-vitro laboratory tests have also not shown any tuberculocidal effects for Mastruz. Further tests are being carried out on the other medicinal plants.

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Lima, Marco A., Antonio Aversa, Pericles Maranhão-Filho, Gabriela A. Lima, Andre Curi, Carolina A. Schmaltz i Flavia M. Santanna. "Optochiasmatic tuberculoma as the sole manifestation of late recurrent tuberculosis". Revista do Instituto de Medicina Tropical de São Paulo 54, nr 4 (sierpień 2012): 229–30. http://dx.doi.org/10.1590/s0036-46652012000400008.

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Brain tuberculomas account for 10-20% of space occupying brain lesions in developing countries. Most lesions are observed at time of tuberculosis diagnosis or soon after starting treatment. We herein describe a 32 year-old patient with a 14-month history of headache and progressive visual loss. Her past medical history revealed pulmonary tuberculosis treated eight years before. A brain MRI showed a T1- and T2-weighted isointense contrast-enhancing lesion in the optic chiasm. A presumptive diagnosis of optochiasmatic tuberculoma was made and isoniazid, rifampin, pyrazinamide, and ethambutol were started. Despite treatment, the patient evolved to blindness. The prompt recognition of this condition is extremely important since the presence of optochiasmal enhancement is associated with blindness in patients with tuberculosis.

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Hussain, Dr Hidayath. "Mediastinal Tuberculosis with Sternal Encroachment - A Rare Presentation of Tuberculosis". Journal of Medical Science and clinical Research 12, nr 01 (31.01.2024): 44–49. http://dx.doi.org/10.18535/jmscr/v12i01.07.

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Introduction Extra-pulmonary tuberculosis constitutes 15-20% of the total tuberculosis (TB) caseload in immunocompetent patients. Affliction of the skeletal system is rare with still rarer presentation of sternal tuberculosis. Sternum is one of the least common bones of the body to get infected (1) Sternal TB is predominantly seen in middle-aged adults although no age is immune and it has also been reported in an infant. It can arise primarily due to a hematogenous route or direct extension from the hilar lymph nodes and/or could be due to lymphatic disseminatio(2) . Sternal tuberculosis has also been reported after BCG vaccination in the pediatric age group (3-5) Here we present an unusual case of tuberculosis of the sternum, which presented with swelling and pain in the chest in a 9 year old boy. Keywords: Sternal tuberculosis, Manubrium sterni, Skeletal Tuberculosis, Pediatric sternal tuberculosis, Mediastinal Koch’s

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Серёгина, В. А., А. М. Будрицкий i Р. Г. Маханьков. "Social Portrait and Clinical Characteristics of the Patients Who Received Treatment at the Bogushevsk Regional Tuberculosis Hospital". Клиническая инфектология и паразитология, nr 3 (24.11.2020): 343–51. http://dx.doi.org/10.34883/pi.2020.9.3.033.

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Проблема туберкулеза остается актуальной в нашей стране и на современном этапе. В работе дана демографическая и социальная характеристика пациентов с наличием лекарственно-устойчивого туберкулеза (ЛУ-ТБ), получивших лечение в Богушевской областной противотуберкулезной больнице (БОТБ) с 2012 по 2016 г. Проанализирована динамика клинических форм, лекарственной чувствительности микобактерий туберкулеза (МБТ) у пациентов с туберкулезом легких при рассмотрении основных категорий пациентов: новые случаи, рецидивы, неудача в лечении, отрыв от лечения. Среди клинических форм туберкулеза легких преобладал инфильтративный туберкулез (68%). Среди пациентов, получивших лечение в Богушевской областной туберкулезной больнице, сельские и городские жители болели туберкулезом одинаково часто. Более чем у 80% пациентов с туберкулезом в анамнезе имелась зависимость от алкоголя и/или табакокурения. Среди пациентов с туберкулезом легких довольно высокий процент отрыва от лечения (14,5%). У пациентов с инфильтративным, диссеминированным туберкулезом легких и казеозной пневмонией преобладали впервые выявленные случаи. У пациентов с фиброзно-кавернозным туберкулезом легких преобладали случаи после неудачи в лечении и отрыва от лечения. Среди клинических форм туберкулеза туберкулемы встречались редко (2015 г. – 1 случай, 2016 г. – 2 случая). The problem of tuberculosis still remains relevant in our country currently. The research presents the demographic and social characteristics of patients with drug-resistant TB (DR-TB) who received treatment at the Bogushevsk Regional Tuberculosis Hospital from 2012 to 2016. The dynamics of clinical forms, drug sensitivity of mycobacterium tuberculosis (MBT) in patients with pulmonarytuberculosis were analyzed when considering the main categories of patients: new cases, relapses, treatment failures, separations from treatment. Among the clinical forms of pulmonary tuberculosis, infiltrative tuberculosis predominated (68%). Among the patients who received treatment at the Bogushevsk Regional Tuberculosis Hospital, rural and urban residents have tuberculosis equally often. More than 80% of patients that had tuberculosis had a history of alcohol and/or tobacco dependence. Among patients with pulmonary tuberculosis a relatively high percentage of separation from treatment (14.5%) was observed. In patients with infiltrative, disseminated pulmonary tuberculosis and caseous pneumonia, newly diagnosed cases prevailed. In patients with fibro-cavernous pulmonary tuberculosis, most cases occurred after treatment failures and separation from treatment. Among the clinical forms of tuberculosis, tuberculomas were rare (2015 – 1 case, 2016 – 2 cases).

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Vera Figueroa, Franco, Manuel Jara-Burgos, Eduardo López Ferrada, Jean Paul Caze Candia, Rafael Contreras Aguayo i Arnold Vargas Soto. "Tuberculoma frontal aislado como simulador de glioma en paciente inmunocompetente sin foco tuberculoso conocido previo. Revisión de literatura a propósito de un caso." Revista Chilena de Neurocirugía 49, nr 1 (25.08.2023): 32–37. http://dx.doi.org/10.36593/revchilneurocir.v49i1.371.

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Introducción: Los tuberculomas cerebrales son una forma presentación rara de tuberculosis (TBC) extrapulmonar, pudiendo simular diversos diferenciales incluidas las neoplasias intraaxiales (gliales y/o metastásicas). Presentación del caso: Varón, 39 años, previamente sano, consultó por cefalea y crisis convulsivas. Tomografía cerebral evidenció una lesión frontal derecha levemente hiperdensa espontáneamente; parcialmente captante de gadolinio en resonancia, informada por neuroradiólogo como “sugerente de glioma de bajo grado versus metástasis”. Tras descartar otra neoplasia primaria, se planificó y realizó cirugía para glioma (exéresis supramarginal). Resultado histológico-molecular compatible con Tuberculosis Cerebral. Paciente evolucionó sin focalidad, siendo evaluado por infectología y equipo de TBC, indicando tratamiento antituberculoso con dosis fija combinada por 50 veces. Discusión: La neuroimagen de tumores cerebrales suele ser compleja pudiendo los tuberculomas simular dichas patologías. Siendo Chile un país aún en vías de erradicación de TBC, es importante considerar a los tuberculomas dentro de las posibilidades diagnósticas.

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Lee, Seung Heon. "Tuberculosis Infection and Latent Tuberculosis". Tuberculosis and Respiratory Diseases 79, nr 4 (2016): 201. http://dx.doi.org/10.4046/trd.2016.79.4.201.

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