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Artykuły w czasopismach na temat "TREK1"
Levitz, Joshua, Perrine Royal, Yannick Comoglio, Brigitte Wdziekonski, Sébastien Schaub, Daniel M. Clemens, Ehud Y. Isacoff i Guillaume Sandoz. "Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels". Proceedings of the National Academy of Sciences 113, nr 15 (28.03.2016): 4194–99. http://dx.doi.org/10.1073/pnas.1522459113.
Pełny tekst źródłaKim, Seong-Seop, Jimin Park, Eunju Kim, Eun Mi Hwang i Jae-Yong Park. "β-COP Suppresses the Surface Expression of the TREK2". Cells 12, nr 11 (29.05.2023): 1500. http://dx.doi.org/10.3390/cells12111500.
Pełny tekst źródłaBai, Xilian, George J. Bugg, Susan L. Greenwood, Jocelyn D. Glazier, Colin P. Sibley, Philip N. Baker, Michael J. Taggart i Gregor K. Fyfe. "Expression of TASK and TREK, two-pore domain K+ channels, in human myometrium". Reproduction 129, nr 4 (kwiecień 2005): 525–30. http://dx.doi.org/10.1530/rep.1.00442.
Pełny tekst źródłaAfzali, Ali M., Tobias Ruck, Alexander M. Herrmann, Janette Iking, Claudia Sommer, Christoph Kleinschnitz, Corinna Preuβe i in. "The potassium channels TASK2 and TREK1 regulate functional differentiation of murine skeletal muscle cells". American Journal of Physiology-Cell Physiology 311, nr 4 (1.10.2016): C583—C595. http://dx.doi.org/10.1152/ajpcell.00363.2015.
Pełny tekst źródłaBlin, Sandy, Ismail Ben Soussia, Eun-Jin Kim, Frédéric Brau, Dawon Kang, Florian Lesage i Delphine Bichet. "Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties". Proceedings of the National Academy of Sciences 113, nr 15 (28.03.2016): 4200–4205. http://dx.doi.org/10.1073/pnas.1522748113.
Pełny tekst źródłaHermanstyne, T. O., K. Markowitz, L. Fan i M. S. Gold. "Mechanotransducers in Rat Pulpal Afferents". Journal of Dental Research 87, nr 9 (wrzesień 2008): 834–38. http://dx.doi.org/10.1177/154405910808700910.
Pełny tekst źródłaPeng, Yuanzhi, Qingqing Zhang, Hao Cheng, Saie Shen i Xiaojian Weng. "Activation of TREK1 Channel in the Anterior Cingulate Cortex Improves Neuropathic Pain in a Rat Model". Computational Intelligence and Neuroscience 2022 (30.09.2022): 1–6. http://dx.doi.org/10.1155/2022/1372823.
Pełny tekst źródłaKim, Seong-Seop, Yeonju Bae, Osung Kwon, Seung-Hae Kwon, Jong Bok Seo, Eun Mi Hwang i Jae-Yong Park. "β-COP Regulates TWIK1/TREK1 Heterodimeric Channel-Mediated Passive Conductance in Astrocytes". Cells 11, nr 20 (21.10.2022): 3322. http://dx.doi.org/10.3390/cells11203322.
Pełny tekst źródłaRoyal, Perrine, Pablo Ávalos Prado, Brigitte Wdziekonski i Guillaume Sandoz. "Canaux potassiques à deux domaines P (K2P) et migraine". Biologie Aujourd'hui 213, nr 1-2 (2019): 51–57. http://dx.doi.org/10.1051/jbio/2019020.
Pełny tekst źródłaBrohawn, Stephen G. "How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2". Annals of the New York Academy of Sciences 1352, nr 1 (31.08.2015): 20–32. http://dx.doi.org/10.1111/nyas.12874.
Pełny tekst źródłaRozprawy doktorskie na temat "TREK1"
Walsh, Yvonne. "Pharmacological regulation of TREK1, TREK2 and TRESK two pore domain potassium channels". Thesis, University of Kent, 2017. https://kar.kent.ac.uk/68081/.
Pełny tekst źródłaSATO, Jun, Kazue MIZUMURA, Ken TAKAHASHI, Kimiaki KATANOSAKA i Yasuko KOZAKI. "Increased C-fiber Activities to Cold in Adjuvant-monoarthritic Rats was not Accompanied by Increased Expression of TREK1 and CMR1 mRNAs(RIEM Conference II, 2002)". Research Institute of Environmental Medicine, Nagoya University, 2002. http://hdl.handle.net/2237/2809.
Pełny tekst źródłaDolcemascolo, Axel. "Laser à semi-conducteur pour modéliser et contrôler des cellules et des réseaux excitables". Thesis, Université Côte d'Azur (ComUE), 2018. http://www.theses.fr/2018AZUR4208/document.
Pełny tekst źródłaExcitable systems are everywhere in Nature, and among them the neuron, which responds to an external stimulus with an all-or-none type of response, is often regarded as the most typical example. This excitability behaviour is clearly established as to be one of the underlying operating mechanisms of the nervous system and its analysis in model systems (being them mathematical of physical) can, from one hand, shed some light on the dynamics of neural networks, and from the other, open novel ways for a neuro-mimetic treatment of information. The work presented in this PhD thesis was realized in this perspective. In this dissertation we will consider systems based on semiconductor lasers both for modelling excitable systems or coupled neuromorphic networks and for controlling (in an optogenetic outlook) ionic channels that are involved in the emission of action potentials of neurons in mammals. During the first chapter, we will briefly present the dynamical concepts on which we will build our understanding for the rest of the manuscript. Thereafter, we will describe the context of this work from the point of view of synchronized systems, in particular excitable cells. Finally, we will discuss in this context the applications potential of this work, namely the possibility of using “neuromimetic” photonic systems as a was to treat information. In chapter 2 we will firstly analyse from a theoretical and bibliographical standpoint the excitable character of a laser with coherent injection. Later, we will firstly detail our results, firstly experimental and subsequently numerical and theoretical, on the response of this “neuromimetic” system to perturbations repeated in time. Whereas the simplified mathematical model envisions an integrator behaviour in response to repeated perturbations, we will show that the system often acts as a resonator, thus imparting the remarkable property of being able to emit a single pulse only if it receives two perturbations that are separated by a specific time interval. We will also illustrate how this system can convert perturbations of different intensity in a series of all identical pulses whose number depends on the intensity of the incoming perturbation. In the third chapter we will analyse, first experimentally and later numerically and theoretically, the dynamical behaviour of a network of coupled semiconductor lasers in a slow-fast chaotic regime. We will rely on a previous study documenting that a single such element can present a neuromimetic dynamics (in particular, the emission of chaotic pulses originating from a canard phenomenon). Surprisingly for a system having such a large number of degrees of freedom, we observe a dynamics which seems low dimensional chaotic. We will examine the impact of statistical properties of the selected population on the dynamics, and we will link our experimental and numerical observations to the existence of a slow manifold for the mean field, computable analytically, and towards whom the dynamics converges thanks to the slow-fact nature of the system. Finally, in chapter 4 we will present a short experimental study on the response of biological cells to light perturbations. Indeed, optogenetic techniques enables to render the cells (in particular neurons) sensitive to light due to the optical control of the opening and closing of ionic channels. Hence, after having studied in the previous chapters optical systems on the basis of observations derived from biological systems, we will physically transfer an optical system towards a biological one. Here we lay the groundwork of a photonic system which allows, with a moderate complexity, to realize cell measurements in response to spatially localized optical perturbations
Schön, Anna. "Utopia Trek : utopibegreppets resa genom Star Trek". Thesis, Linköping University, Department of Thematic Studies, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2539.
Pełny tekst źródłaHumanity has always dreamed about a better world. These dreams has manifested themselves in the vision of Utopia - the good place, but also the non-existing place. Up until World War II man still wrote optimistic descriptions of this ideal world, and spread the idea through literature. In the aftermath of the atomic bomb and under the influence of the cold war, these publications seized to surface in literary surroundings. Despite this utopia did not die - it has only changed. Today you can find utopia, not primarily in books, but in Science Fiction. TV’s biggest Science Fiction-series, Star Trek, is perhaps the best example of this. The Master's thesis "Utopia Trek - a travel through Star Trek with the concept of utopia" takes you through the history of utopia and into its new habitat, Star Trek, where the essence of a utopia for the 21th century is found, discussed and reevaluated.
Mänskligheten har alltid drömt om en bättre värld. Dessa drömmar har manifesterats i visionen om Utopia - den goda platsen, men också platsen som inte existerar. Fram till andra världskriget skrev man fortfarande optimistiska beskrivningar av denna idealvärld, och spred idén via litteraturen. Efter hotet från atombomben och under påverkan av det kalla kriget, slutade dessa publikationer att dyka uppi litterära sammanhang. Trots detta dog inte drömmen utopia - det har bara förändrats. Idag kan man finna utopia, inte företrädesvis i böcker, utan i science fiction. Tv:s största science fiction-serie, Star Trek, är kanske det bästa exemplet på detta. Magisteruppsatsen "Utopia Trek - utopibegreppets resa genom Star Trek" tar dig genom utopias historia och in i dess nya hemvist, Star Trek, där essensen av ett utopia för 2000-talet upptäcks, diskuteras och omvärderas.
Geraghty, Lincoln. "Living with Star Trek : utopia, community, self-improvement and the Star Trek universe". Thesis, University of Nottingham, 2005. http://eprints.nottingham.ac.uk/10982/.
Pełny tekst źródłaValverde, Estrella Lorena. "TREX1 and SAMHD1, and Aicardi-Goutières Syndrome". Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/291940.
Pełny tekst źródłaLa síndrome d'Aicardi-Goutières (AGS), és una malaltia autoimmunitària recessiva que mimetitza una infecció vírica intrauterina, i la qual és caracteritzada per calcificacions intracranials, atròfia cerebral i augment d'IFN-alfa al líquid cefaloraquidi. L'AGS és una malaltia genètica heterogènia associada amb mutacions al gen que codifica per a l'exonucleasa TREX1, a qualsevol dels gens codificants per a les components de la ribonucleasa RNASE H2, a la fosfohidrolasa SAMHD1, a la deaminasa ADAR1 o al sensor citoplasmàtic MDA5. El coneixement d'aquestes funcions és fonamental per tal d'entendre la patogènesi de l'AGS. En aquesta tesi s'ha aprofundit en el coneixement del mecanisme regulador de la transcripció de Samhd1. Hem vist que Samhd1 es troba expressat en diferents òrgans sense necessitat de cap estímul previ, com el pàncrees, l’intestí prim i els macròfags derivats de moll d’os, i en diferents quantitats en altres òrgans de ratolí. Donada la important afectació que té l’AGS al cervell, també es va analitzar la seva expressió en neurones i cèl·lules de la micròglia. També hem vist que Samhd1 es troba induït en presència de citocines proinflamatòries, però no es troba afectada la seva expressió en presència de citocines antiinflamatòries així com tampoc en presència de TNF-gamma. Utilitzant macròfags derivats de ratolins deficients en STAT1, hem pogut demostrar que l’expressió de Samhd1 per IFN-alfa és a través d’STAT1, ja que la seva expressió es troba completament reprimida en aquestes cèl·lules. Ens vam centrar en la inducció de Samhd1 i per la seva comprensió vam focalitzar en l’estudi del seu promotor. Es van clonar 1500 parells de bases del promotor de Samhd1 en un plasmidi reporter de luciferasa, i es va veure que aquest fragment era suficient per induir l’expressió de luciferasa. A partir d’aquest constructe, es van realitzar llavors noves construccions delecionant cada vegada una regió del promotor. Es va veure que en delecionar una regió específica de 161pb, l’expressió de luciferasa es trobava completament reprimida, indicant que aquesta regió del promotor és crítica per a la inducció de Samhd1. Experiments de retard en gel (EMSA) van mostrar que Samhd1 es troba reprimit en condicions basals per una proteïna que no hem arribat a caracteritzar, i experiments de precipitació de cromatina (ChIP) van mostrar que IRF1 es troba involucrada en la inducció de Samhd1 per IFN-alfa. La nostra hipòtesi doncs, és que l’expressió de Samhd1 té un mecanisme de regulació doble: en condicions basals es troba reprimit i en presència d’IFN-alfa s’indueix una via de senyalització independent d’STAT1 que fa saltar el complex repressor del promotor, i també s’indueix una via de senyalització dependent d’STAT1, que indueix l’expressió d’IRF1 i que activa la transducció de Samhd1. Fins ara no hem caracteritzat la proteïna o complex de proteïnes que reprimeix l’expressió de Samhd1 en condicions basals, però s’està investigant mitjançant anàlisis proteòmics. En aquesta tesi també s’ha fet la construcció d’un ratolí KO condicional per a TREX1. Una vegada aconseguit aquest animal condicional, el qual conté el gen de Trex1 flanquejat per dues dianes LoxP, aquest s’està encreuant amb diferents soques que expressen CRE sota regulació de diferents Socs2 promotors. Els ratolins homozigots KO i que expressen CRE, tenen un fenotip similar al fenotip que mostren els ratolins KO totals de TREX1. Estem en el procés d’obtenció de ratolins homozigots KO i que expressen CRELysM però, donat a problemes amb la penetrància d’aquest al·lel, hem tingut algunes dificultats. Els resultats d’aquesta tesi en conjunt poden ajudar a entendre una mica més el funcionament de l'AGS.
Roy, André 1963. "Une lecture politique de Star trek /". Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61800.
Pełny tekst źródłaHawkey, Kate. "Beginning and becoming : a narrative trek". Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684911.
Pełny tekst źródłaLyons, Reneé C. "Trips and Treks: Teaching Endangered Species Through Literature". Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2367.
Pełny tekst źródłaInnamaa, Anni. "Expression and function of the two pore potassium (K2P) channels TREK-1, TREK-2 and TASK-3 in ovarian cancer". Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606812.
Pełny tekst źródłaKsiążki na temat "TREK1"
Trek. London: Corgi, 2007.
Znajdź pełny tekst źródłaPaul, Stewart. Trek. London: Cape, 1991.
Znajdź pełny tekst źródłaTrek. Rearsby: W F Howes, 2009.
Znajdź pełny tekst źródłaLondon, Jack. Serdt︠s︡a trekh. Kharʹkov: Folio, 1998.
Znajdź pełny tekst źródłaNorris, Dorothy Tinnin. Tinnin treks. Houston, Mo: D.T. Norris, 1989.
Znajdź pełny tekst źródłaDunham, Judith. Backcountry treks. Singapore: Discovery Communications, 2000.
Znajdź pełny tekst źródłaMerezhkovsky, Dmitry Sergeyevich. Taĭna trekh. Moskva: Izd-vo "Respublika", 1999.
Znajdź pełny tekst źródłaJudith, Dunham, red. Backcountry treks. Bethesda, MD: Discovery Communications, 2000.
Znajdź pełny tekst źródłaDunham, Judith. Backcountry treks. Singapore: Discovery Communications, 2000.
Znajdź pełny tekst źródłaChernomorskiĭ flot v trekh voĭnakh i trekh revoli︠u︡t︠s︡ii︠a︡kh. Moskva: AST, 2007.
Znajdź pełny tekst źródłaCzęści książek na temat "TREK1"
Šiljak, Harun. "Normed Trek". W Murder on the Einstein Express and Other Stories, 3–10. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29066-9_1.
Pełny tekst źródłaDewdney, Alexander Keewatin. "The Trek". W The Planiverse, 83–106. New York, NY: Springer New York, 2000. http://dx.doi.org/10.1007/978-1-4613-0199-8_6.
Pełny tekst źródłaTahan, Mary R. "Snow Trek". W Roald Amundsen’s Sled Dogs, 387–414. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-02692-9_29.
Pełny tekst źródłaArtzt, Karen, i Jiang I. Wu. "Star Trek". W Advances in Experimental Medicine and Biology, 1–24. Boston, MA: Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-7005-3_1.
Pełny tekst źródłaHark, Ina Rae. "Trekker’s Log, Stardate 1908200.7". W Star Trek, 1–7. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_1.
Pełny tekst źródłaHark, Ina Rae. "Course Plotted and Laid In". W Star Trek, 8–20. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_2.
Pełny tekst źródłaHark, Ina Rae. "Star Trek: This Side of Paradise". W Star Trek, 21–57. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_3.
Pełny tekst źródłaHark, Ina Rae. "Star Trek: The Next Generation: The Best of Both Worlds". W Star Trek, 58–87. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_4.
Pełny tekst źródłaHark, Ina Rae. "Star Trek: Deep Space Nine: Necessary Evil". W Star Trek, 88–115. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_5.
Pełny tekst źródłaHark, Ina Rae. "Star Trek: Voyager: Time and Again". W Star Trek, 116–34. London: British Film Institute, 2008. http://dx.doi.org/10.1007/978-1-349-92226-0_6.
Pełny tekst źródłaStreszczenia konferencji na temat "TREK1"
Fickas, Stephen, McKay Sohlberg i Jason Prideaux. "TREK". W the 7th international conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1463689.1463717.
Pełny tekst źródłaMarques, Leonardo, Mauro Amazonas, Thais Castro, Willian Assuncao, Luciana Zaina, Bruno Gadelha i Tayana Conte. "UX trek". W IHC '20: XIX Brazilian Symposium on Human Factors in Computing Systems. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3424953.3426547.
Pełny tekst źródłaSinnott, Richard O. "Cloud Trek". W UCC '17: 10th International Conference on Utility and Cloud Computing. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3147213.3155014.
Pełny tekst źródłaHorta, Edson, Ho-Ren Chuang, Naarayanan Rao VSathish, Cesar Philippidis, Antonio Barbalace, Pierre Olivier i Binoy Ravindran. "Xar-trek". W Middleware '21: 22nd International Middleware Conference. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3464298.3493388.
Pełny tekst źródłaBalan, V. "CMP-Stack Trek". W 2016 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2016. http://dx.doi.org/10.7567/ssdm.2016.k-2-01.
Pełny tekst źródłaDatz, Suzanne. "Star Trek---the experience". W ACM SIGGRAPH 97 Visual Proceedings: The art and interdisciplinary programs of SIGGRAPH '97. New York, New York, USA: ACM Press, 1997. http://dx.doi.org/10.1145/259081.259492.
Pełny tekst źródłaDudak, Celal, Emrah Oncu, Koray Karakus, Neslin Ismailoglu i Volkan Akan. "Variations on the theme of TREKS-823". W 2013 6th International Conference on Recent Advances in Space Technologies (RAST). IEEE, 2013. http://dx.doi.org/10.1109/rast.2013.6581297.
Pełny tekst źródłaShimizu, Suguru. "Active polarimeter system for TREK experiment". W 2009 KAON International Conference. Trieste, Italy: Sissa Medialab, 2010. http://dx.doi.org/10.22323/1.083.0016.
Pełny tekst źródłaDjalali, Chaden, i TREK Collaboration. "The TREK program at J-PARC". W IX LATIN AMERICAN SYMPOSIUM ON NUCLEAR PHYSICS AND APPLICATIONS. AIP, 2012. http://dx.doi.org/10.1063/1.3688817.
Pełny tekst źródłaKohl, M., i TREK Collaboration. "The TREK/E36 experiment at J-PARC". W WORKSHOP TO EXPLORE PHYSICS OPPORTUNITIES WITH INTENSE, POLARIZED ELECTRON BEAMS AT 50-300 MEV. AIP, 2013. http://dx.doi.org/10.1063/1.4829396.
Pełny tekst źródłaRaporty organizacyjne na temat "TREK1"
Bruce Ohme. Deep Trek High Temperature Electronics Project. Office of Scientific and Technical Information (OSTI), lipiec 2007. http://dx.doi.org/10.2172/923033.
Pełny tekst źródłaBruce Ohme i Michael Johnson. Deep Trek Re-configurable Processor for Data Acquisition (RPDA). Office of Scientific and Technical Information (OSTI), czerwiec 2009. http://dx.doi.org/10.2172/982893.
Pełny tekst źródłaDesilets, Y., M. Fafard, M. Lasserre, S. Lebeau, M J Manore i B. Ramsay. RADARSAT Helps High-Tech Trek to the Magnetic North Pole. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1996. http://dx.doi.org/10.4095/218978.
Pełny tekst źródłaKohl, Michael. Closeout Report - Search for Time Reversal Symmetry Violation with TREK at J-PARC. Office of Scientific and Technical Information (OSTI), kwiecień 2015. http://dx.doi.org/10.2172/1212319.
Pełny tekst źródłaKevin D. Edgley, Fred L. Sabins i Larry T. Watters. Supercement for Annular Seal and Long-Term Integrity in Deep, Hot Wells "Deep Trek". Office of Scientific and Technical Information (OSTI), sierpień 2005. http://dx.doi.org/10.2172/908315.
Pełny tekst źródłaFrykman, P. N., E. A. Harman, J. F. Patton, P. K. Opstad i R. W. Hoyt. Effects of a World Record Unsupported Ski Trek Across Greenland (The G2 Expedition) on Physical Performance and Body Composition. Fort Belvoir, VA: Defense Technical Information Center, sierpień 2001. http://dx.doi.org/10.21236/ada396385.
Pełny tekst źródłaNjå, Ove, i Kirsti Russell Vastveit. Norske kommuners planlegging, gjennomføring og bruk av risiko- og sårbarhetsanalyse i forbindelse med samfunnssikkerhetsarbeidet. University of Stavanger, październik 2016. http://dx.doi.org/10.31265/usps.164.
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