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Artykuły w czasopismach na temat "Translation regulatory network"
Pérez-Morales, Deyanira, Jessica Nava-Galeana, Roberto Rosales-Reyes, Paige Teehan, Helen Yakhnin, Erika I. Melchy-Pérez, Yvonne Rosenstein, Miguel A. De la Cruz, Paul Babitzke i Víctor H. Bustamante. "An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella Typhimurium". PLOS Pathogens 17, nr 5 (28.05.2021): e1009630. http://dx.doi.org/10.1371/journal.ppat.1009630.
Pełny tekst źródłaBarbuti, Roberto, Pasquale Bove, Roberta Gori, Damas Gruska, Francesca Levi i Paolo Milazzo. "Encoding Threshold Boolean Networks into Reaction Systems for the Analysis of Gene Regulatory Networks". Fundamenta Informaticae 179, nr 2 (10.03.2021): 205–25. http://dx.doi.org/10.3233/fi-2021-2021.
Pełny tekst źródłaKalous, Jaroslav, i Daria Aleshkina. "Multiple Roles of PLK1 in Mitosis and Meiosis". Cells 12, nr 1 (2.01.2023): 187. http://dx.doi.org/10.3390/cells12010187.
Pełny tekst źródłaChang, Lynne, Yaron Shav-Tal, Tatjana Trcek, Robert H. Singer i Robert D. Goldman. "Assembling an intermediate filament network by dynamic cotranslation". Journal of Cell Biology 172, nr 5 (27.02.2006): 747–58. http://dx.doi.org/10.1083/jcb.200511033.
Pełny tekst źródłaGoldenkova-Pavlova, Irina, Olga Pavlenko, Orkhan Mustafaev, Igor Deyneko, Ksenya Kabardaeva i Alexander Tyurin. "Computational and Experimental Tools to Monitor the Changes in Translation Efficiency of Plant mRNA on a Genome-Wide Scale: Advantages, Limitations, and Solutions". International Journal of Molecular Sciences 20, nr 1 (21.12.2018): 33. http://dx.doi.org/10.3390/ijms20010033.
Pełny tekst źródłaSudalagunta, Praneeth Reddy, Rafael Renatino Canevarolo, Mark Meads, Maria Coelho Silva, Xiaohong Zhao, Raghunandan Reddy Alugubelli, Joon-hyun Song i in. "Abstract 4313: A novel gene regulatory network model identifies master regulators in cancer". Cancer Research 83, nr 7_Supplement (4.04.2023): 4313. http://dx.doi.org/10.1158/1538-7445.am2023-4313.
Pełny tekst źródłaFarley, Brian M., i Sean P. Ryder. "POS-1 and GLD-1 repress glp-1 translation through a conserved binding-site cluster". Molecular Biology of the Cell 23, nr 23 (grudzień 2012): 4473–83. http://dx.doi.org/10.1091/mbc.e12-03-0216.
Pełny tekst źródłaZamani, Zahra, Amirhossein Hajihosseini i Ali Masoudi-Nejad. "Computational Methodologies for Analyzing, Modeling and Controlling Gene Regulatory Networks". Biomedical Engineering and Computational Biology 2 (styczeń 2010): BECB.S5594. http://dx.doi.org/10.4137/becb.s5594.
Pełny tekst źródłaSpirov, Alexander V., Ekaterina M. Myasnikova i David M. Holloway. "Sequential construction of a model for modular gene expression control, applied to spatial patterning of theDrosophilagenehunchback". Journal of Bioinformatics and Computational Biology 14, nr 02 (kwiecień 2016): 1641005. http://dx.doi.org/10.1142/s0219720016410055.
Pełny tekst źródłaAlshabi, Ali Mohamed, Basavaraj Vastrad, Ibrahim Ahmed Shaikh i Chanabasayya Vastrad. "Identification of Crucial Candidate Genes and Pathways in Glioblastoma Multiform by Bioinformatics Analysis". Biomolecules 9, nr 5 (24.05.2019): 201. http://dx.doi.org/10.3390/biom9050201.
Pełny tekst źródłaRozprawy doktorskie na temat "Translation regulatory network"
Freschi, Luca. "Post-translational modifications regulatory networks : evolution, mechanisms et implications". Doctoral thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/25812.
Pełny tekst źródłaPost-translational modifications (PTMs) are chemical modification of proteins that allow the cell to finely tune its functions as well as to encode and integrate environmental signals. The recent advancements in the experimental and bioinformatic techniques have allowed us to determine the PTM profiles of entire proteomes as well as to identify the molecules that write or erase PTMs to/from each protein. This data have made possible to define cellular PTM regulatory networks. Here, we study the evolution of these networks to get new insights about how they may contribute to increase organismal complexity and diversity and to better understand their molecular mechanisms of functioning. We first address the question of how and to which extent a PTM network can be rewired after a gene duplication event, by studying how the budding yeast phosphoregulatory network was rewired after a whole genome duplication event that occurred 100 million years ago. Our results highlight the role of gene duplication as a key mechanism to innovate and complexify PTM regulatory networks. Then, we address the question of how PTM networks may contribute to organismal diversity by comparing the human and mouse phosphorylation profiles. We find that there are substantial differences in the PTM profiles of these two species that have the potential to explain, at least in part, the phenotypic differences observed between them. Moreover, we find evidence supporting the idea that PTMs can jump to new positions during evolution and still regulate the same biological functions. This phenomenon should be taken into account when comparing the PTM profiles of different species, in order to avoid overestimating the divergence in PTM regulation. Finally, we investigate how multiple and alternative PTMs that affect the same residues interact with each other to control proteins functions. We focus on two of the most studied PTMs, protein phosphorylation and O-GlcNAcylation, that affect serine and threonine residues and we study their potential mechanisms of interactions in human and mouse. Our results support the hypothesis that these two PTMs control multiple biological functions rather than a single one. Globally this work provides new findings that elucidate the evolutionary dynamics, the functional mechanisms and the biological implications of PTMs.
Pontheaux, Florian. "Activité traductionnelle et dynamique mitotique induites par la fécondation chez l’oursin". Electronic Thesis or Diss., Sorbonne université, 2022. http://www.theses.fr/2022SORUS209.
Pełny tekst źródłaFine tuning of translation for cell cycle dynamics remains an important topic in cell research. During my thesis, I analyzed the relationships between mRNA translational activity and mitotic cell division using sea urchin embryos. Egg fertilization triggers the activation of the translational machinery, which is required for resuming the first mitotic division, independently of any transcription. A Translational Regulatory Network (TlRN) remains to be identified and characterized upstream of the cell cycle actors. Seeking mitotic activities that can help visualize spatial dynamics inside isolated eggs, I obtained original data showing the spatial and dynamic activity of the mitotic complex CyclinB/CDK1 and the phosphorylation of histone H3 at threonine 3 (pH3T3) during embryonic mitosis. Then, I analyzed the in vivo role of specific 5’UTR for controlling the mRNA recruitment onto active polysome following fertilization. Finally, I showed that the translation of the mRNA encoding for eIF4B (eukaryotic Initiation Factor 4B) controls the translational activity and dynamics of the first two mitotic divisions induced by fertilization. I propose that eIF4B acts as a positive regulator within the TlRN. These data will allow to study the potential effect of eIF4B acting upstream the spatial dynamics of CDK1 and pH3T3 activities
Tan, Elizabeth E.-Lyn. "Immuno-metabolism in Metabolic (dysfunction) associated fatty liver disease (MAFLD)". Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27978.
Pełny tekst źródłaEckmann, Christian R., Mark Schmid, Adam P. Kupinski, Britta Jedamzik, Martin Harterink i Agata Rybarska. "GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-184095.
Pełny tekst źródłaEckmann, Christian R., Mark Schmid, Adam P. Kupinski, Britta Jedamzik, Martin Harterink i Agata Rybarska. "GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions". PLOS Genetics, 2009. https://tud.qucosa.de/id/qucosa%3A28993.
Pełny tekst źródłaCampbell, Pearl. "Pou5f1 Post-translational Modifications Modulate Gene Expression and Cell Fate". Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23607.
Pełny tekst źródłaSurappa-Narayanappa, Ananth Prakash. "The evolution, modifications and interactions of proteins and RNAs". Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/269851.
Pełny tekst źródłaGhaffari, Noushin. "Genomic Regulatory Networks, Reduction Mappings and Control". Thesis, 2012. http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10726.
Pełny tekst źródłaDey, Souvik. "Transcriptional regulation of ATF4 is critical for controlling the Integrated Stress Response during eIF2 phosphorylation". Thesis, 2012. http://hdl.handle.net/1805/3041.
Pełny tekst źródłaIn response to different environmental stresses, phosphorylation of eIF2 (eIF2P) represses global translation coincident with preferential translation of ATF4. ATF4 is a transcriptional activator of the integrated stress response, a program of gene expression involved in metabolism, nutrient uptake, anti-oxidation, and the activation of additional transcription factors, such as CHOP/GADD153, that can induce apoptosis. Although eIF2P elicits translational control in response to many different stress arrangements, there are selected stresses, such as exposure to UV irradiation, that do not increase ATF4 expression despite robust eIF2P. In this study we addressed the underlying mechanism for variable expression of ATF4 in response to eIF2P during different stress conditions and the biological significance of omission of enhanced ATF4 function. We show that in addition to translational control, ATF4 expression is subject to transcriptional regulation. Stress conditions such as endoplasmic reticulum stress induce both transcription and translation of ATF4, which together enhance expression of ATF4 and its target genes in response to eIF2P. By contrast, UV irradiation represses ATF4 transcription, which diminishes ATF4 mRNA available for translation during eIF2∼P. eIF2P enhances cell survival in response to UV irradiation. However, forced expression of ATF4 and its target gene CHOP leads to increased sensitivity to UV irradiation. In this study, we also show that C/EBPβ is a transcriptional repressor of ATF4 during UV stress. C/EBPβ binds to critical elements in the ATF4 promoter resulting in its transcriptional repression. The LIP isoform of C/EBPβ, but not the LAP version is regulated following UV exposure and directly represses ATF4 transcription. Loss of the LIP isoform results in increased ATF4 mRNA levels in response to UV irradiation, and subsequent recovery of ATF4 translation, leading to enhanced expression of its target genes. Together these results illustrate how eIF2P and translational control, combined with transcription factors regulated by alternative signaling pathways, can direct programs of gene expression that are specifically tailored to each environmental stress.
Części książek na temat "Translation regulatory network"
Miyamoto-Sato, Etsuko. "Next-Generation Sequencing Coupled with a Cell-Free Display Technology for Reliable Interactome of Translational Factors". W Transcription Factor Regulatory Networks, 23–32. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0805-9_3.
Pełny tekst źródłaCheok, Yi Ying, Suhailah Abdullah i Won Feng Wong. "Transcriptional regulatory network associated with multiple sclerosis pathogenesis". W Transcription and Translation in Health and Disease, 359–68. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-99521-4.00018-0.
Pełny tekst źródłaYousefi, Mohammadmahdi Rezaei. "Optimal Intervention Methods for Markovian Gene Regulatory Networks". W Data Analytics in Medicine, 1110–47. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1204-3.ch057.
Pełny tekst źródłaCarvalho, P., G. Elias da Silva i N. J. M. Saibo. "Understanding the genetics of C3 photosynthesis in crop plants". W Understanding and improving crop photosynthesis, 31–72. Burleigh Dodds Science Publishing, 2023. http://dx.doi.org/10.19103/as.2022.0119.03.
Pełny tekst źródłaDang, Nitika. "Current Practice of Sleep Medicine in India". W The Practice of Sleep Medicine Around The World: Challenges, Knowledge Gaps and Unique Needs, 181–94. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815049367123010018.
Pełny tekst źródłaRoss, John, Igor Schreiber i Marcel O. Vlad. "Mini-Introduction to Bioinformatics". W Determination of Complex Reaction Mechanisms. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780195178685.003.0015.
Pełny tekst źródłaAmenta, Valentina, Adriana Lazzaroni i Laura Abba. "Internet Identity and the Right to be Forgotten". W Handbook of Research on Redesigning the Future of Internet Architectures, 32–46. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-8371-6.ch002.
Pełny tekst źródłaTong, Ling, Shuanghao Yong, Wei Li, Xiao Yang i Xing Wang. "ARES-Kcr: A New Network Model Utilizing Attention Mechanism and Residual Structure for the Prediction of Lysine Crotonylation Sites". W Studies in Health Technology and Informatics. IOS Press, 2023. http://dx.doi.org/10.3233/shti230877.
Pełny tekst źródłaAltay, Halit Yusuf, Fatma Özdemir, İskalen Cansu Topçu Okan, Yeşim Tütüncü i Cavit Ağca. "Gen Düzenleyici Araçlar ve Bunların Translasyonel Yönleri". W Moleküler Biyoloji ve Genetik, 207–34. Türkiye Bilimler Akademisi, 2023. http://dx.doi.org/10.53478/tuba.978-625-8352-48-1.ch08.
Pełny tekst źródłaStreszczenia konferencji na temat "Translation regulatory network"
Liu, Yu, Yang Liu, Zhengtao Xiao i Xuerui Yang. "Abstract A2-54: DNA methylation-dependent transcription regulatory networks elucidate dynamics of transcription regulatory circuitry in cancers". W Abstracts: AACR Special Conference: Translation of the Cancer Genome; February 7-9, 2015; San Francisco, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.transcagen-a2-54.
Pełny tekst źródłaWu, Daniel Duanqing, Xiaohua Hu i Tingting He. "Exploratory Analysis of Protein Translation Regulatory Networks Using Hierarchical Random Graphs". W 2009 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2009. http://dx.doi.org/10.1109/bibm.2009.38.
Pełny tekst źródłaSingh, Abhyudai, i Joao Pedro Hespanha. "Reducing noise through translational control in an auto-regulatory gene network". W 2009 American Control Conference. IEEE, 2009. http://dx.doi.org/10.1109/acc.2009.5160206.
Pełny tekst źródłaFujita, Andre, Carme Camps, Jiannis Ragoussis, Satoru Miyano i Patricia Severino. "Abstract A18: Assessing microRNA regulatory networks for biomarker discovery in cancer". W Abstracts: AACR International Conference on Translational Cancer Medicine-- Jul 11-14, 2010; San Francisco, CA. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1078-0432.tcmusa10-a18.
Pełny tekst źródłaPires, Bruno R. B., Gerson M. Ferreira, Renata Binato i Eliana Abdelhay. "Abstract A45: Regulatory network of the metastatic process in breast cancer". W Abstracts: AACR International Conference held in cooperation with the Latin American Cooperative Oncology Group (LACOG) on Translational Cancer Medicine; May 4-6, 2017; São Paulo, Brazil. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1557-3265.tcm17-a45.
Pełny tekst źródłaAbate-Shen, Cory. "Abstract IA5: Using cross-species analysis of genome-wide regulatory networks to identify drivers of cancer malignancy". W Abstracts: AACR Special Conference: The Translational Impact of Model Organisms in Cancer; November 5-8, 2013; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1557-3125.modorg-ia5.
Pełny tekst źródłaRaporty organizacyjne na temat "Translation regulatory network"
Chen, Junping, Zach Adam i Arie Admon. The Role of FtsH11 Protease in Chloroplast Biogenesis and Maintenance at Elevated Temperatures in Model and Crop Plants. United States Department of Agriculture, maj 2013. http://dx.doi.org/10.32747/2013.7699845.bard.
Pełny tekst źródłaShale Gas: Strategic, Technical, Environmental and Regulatory Issues. Universidad de Deusto, 2016. http://dx.doi.org/10.18543/tszi1191.
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