Rozprawy doktorskie na temat „Transcription”
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Elzi, David John. "Transcriptional properties of the Kaiso class of transcription factors /". Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/5027.
Pełny tekst źródłaPombo, Ana Maria Pires. "Transcription factories : sites of transcriptional activity in mammalian nuclei". Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268165.
Pełny tekst źródłaXie, Yunwei. "Nucleosomes, transcription and transcription regulation in Archaea". Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1127830717.
Pełny tekst źródłaTitle from first page of PDF file. Document formatted into pages; contains xiv, 200 p.; also includes graphics (some col.). Includes bibliographical references (p. 167-197). Available online via OhioLINK's ETD Center
Xie, Yunwei. "nucleosome, transcription and transcription regulation in Archaea". The Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=osu1127830717.
Pełny tekst źródłaDennis, Jonathan Hancock. "Transcriptional regulation by Brn 3 POU domain containing transcription factors". Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249684.
Pełny tekst źródłaChambers, Anna Louise. "Transcription termination by a transcription-repair coupling factor". Thesis, University of Bristol, 2005. http://hdl.handle.net/1983/b95a2024-73ae-460d-89bf-3c064a780c78.
Pełny tekst źródłaYao, Ya-Li. "Regulation of yy1, a multifunctional transciption [sic] factor /". [Tampa, Fla.] : University of South Florida, 2001. http://purl.fcla.edu/fcla/etd/SFE0000626.
Pełny tekst źródłaBrehm, Alexander Jorg Georg. "Octamer-dependent transcriptional activation by the embryonal transcription factor Oct-4". Thesis, Open University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338344.
Pełny tekst źródłaAlbhilal, Waleed Sulaiman. "The Arabidopsis thaliana heat shock transcription factor A1b transcriptional regulatory network". Thesis, University of Essex, 2015. http://repository.essex.ac.uk/15732/.
Pełny tekst źródłaKwek, Kon Yew. "Regulation of general transcription factor IIH (TFIIH) in transcription". Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427628.
Pełny tekst źródłaToedling, Joern Michael. "Comprehensive analysis of high-throughput experiments for investigating transcription and transcriptional regulation". Thesis, University of Cambridge, 2009. https://www.repository.cam.ac.uk/handle/1810/267885.
Pełny tekst źródłaTruscott, Mary. "The molecular basis of transcriptional activation by the CDP/Cux transcription factor /". Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103187.
Pełny tekst źródłaCDP/Cux was originally described as a repressor of transcription. My goal was to verify whether CDP/Cux might also participate in transcriptional activation and characterize the molecular basis for transcriptional activation by CDP/Cux. Using the DNA polymerase alpha gene promoter as a model system, I showed that stimulation of a DNA pol alpha reporter correlated with DNA binding. Importantly, p110 CDP/Cux stimulated expression from the endogenous DNA pol alpha promoter. Linker-scanning analysis of the DNA pol alpha promoter identified a cis-element that was required for p110-mediated activation, yet was not bound by it. I determined that E2F1 and E2F2 cooperated with p110 in activating the DNA pol alpha promoter, and did so via this cis-element. Furthermore, CDP/Cux recruited these E2Fs to the promoter in chromatin immunoprecipitation experiments. Location array analysis revealed many targets common to p110 and E2F1. DNA metabolism and cell cycle targets were overrepresented, and further studies showed that p110 and E2F cooperated to activate many cell cycle genes.
I also described a second proteolytic event, which generated an isoform lacking two active repression domains in the C-terminus. Processing was observed in S phase, but not in early G1, suggesting that processing occurs in proliferating cells. I determined that caspases were responsible for this processing, and that this occurs in non-apoptotic conditions. A C-terminally-truncated CDP/Cux protein was a more potent activator of cell cycle-regulated promoters, and accelerated entry of Kit225 T cells into S phase, while uncleavable p110 CDP/Cux proteins were inactive in both assays. These results identified p110 CDP/Cux as a substrate of caspases in proliferating cells, and suggested a mechanism by which caspases may accelerate cell cycle progression.
Ching, Chi-yun Johannes, i 程子忻. "Transcriptional regulation of p16INK4a expression by the forkhead box transcription factor FOXM1". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29466192.
Pełny tekst źródłaCusack, Martin. "The role of DNA methylation on transcription factor occupancy and transcriptional activity". Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:7d0b7fe7-dee1-433f-8656-c9ee2a216d48.
Pełny tekst źródłaXu, Meng. "Specialised transcription factories". Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:a41d3243-c233-491a-916b-4e329cace434.
Pełny tekst źródłaYoung, David Alan. "Plant mitochondrial transcription". Thesis, University of East Anglia, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338216.
Pełny tekst źródłaTucker, Nicholas Peter. "Regulation of transcription by the nitric oxide sensing transcription factor NorR". Thesis, University of East Anglia, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426424.
Pełny tekst źródłaLin, Charles Yang. "c-Myc regulates transcriptional pause release and is a global amplifier of transcription". Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/77782.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references (p. 203-226).
Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression and poor clinical outcome. However, the predominant mechanism by which c-Myc regulates global transcription in both healthy and tumor cells is poorly understood. In this thesis, I present evidence that c-Myc is a global regulator of RNA Polymerase II (RNA Pol II) transcriptional pause release. Transcriptional pausing occurs when additional regulatory steps are required to promote elongation of genes after transcription has initiated. Chapter 2 identifies transcriptional pausing as a general feature of transcription by RNA Pol II in mammalian cells. c-Myc is identified as having a major role in promoting release from pause at its target genes. Chapter 3 finds in tumor cells with elevated c-Myc, the transcription factor binds to promoters and enhancers of most actively transcribed genes. The predominant effect of c-Myc binding is to produce higher levels of transcription by promoting RNA Pol II transcriptional pause release. Thus, c-Myc accumulates in the promoter regions of active genes across the cancer cell genome and causes transcriptional amplification, producing increased levels of transcripts within the cells gene expression program. These results imply that transcriptional amplification can reduce rate-limiting constraints for tumor cell growth and proliferation.
by Charles Yang Lin.
Ph.D.
SICILIANO, DILETTA. "ANALYSIS OF THE TRANSCRIPTIONAL REGULATION OF MTORC1 ACTIVITY BY MIT/TFE TRANSCRIPTION FACTORS". Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/607642.
Pełny tekst źródłaImmarigeon, Clément. "Role of mediator complex subunits in transcriptional regulation by GATA and FOG transcription factors during Drosophila development". Toulouse 3, 2014. http://thesesups.ups-tlse.fr/2654/.
Pełny tekst źródłaA major aim of today's research in Biology is to understand how the thousands of genes composing the genome are regulated in order to be expressed in the right cells at the right time. This regulation occurs in large part before gene transcription, at the pre-initiation step. This process results of the concerted action of many proteins, including the large Mediator complex (MED, ~30 protein subunits, >1. 5 MDa), which plays a conserved and crucial role in the regulation of protein-coding genes transcription by RNA polymerase II (PolII), from yeast to humans. This modular complex makes direct core contacts with PolII and general transcription factors, while some subunits can bind to DNA-bound specific transcription factors (TFs). TFs recognize and bind specific regulatory DNA sequences, and drive the tissue-specific expression of their target genes during development. The ubiquitously expressed MED is thought to integrate a cell-specific STF "code" to regulate PolII recruitment and activity at gene promoters. Drosophila melanogaster is a valuable animal model that provides many genetic tools - such as mutant strains and transgenic lines - to address important biological questions in vivo, such as how gene transcription is regulated. A family of TFs, the GATAs, is involved in diverse developmental processes in both Drosophila and vertebrates. They are both activator and repressor TFs, depending on the target gene and the available cofactors, such as Friend Of GATA (FOG) family proteins. The work presented here aimed to understand how GATA TFs use the MED to regulate their target genes both positively and negatively. During the course of this work we generated the first Drosophila mutants for Med1, and investigated the functions of this important subunit in vivo, known as a cofactor of GATAs in vertebrates. We identified a subset of Drosophila MED subunits (including Med1, 12, 13, 15, 19) which are required for proper GATA-dependent processes, such as haematopoiesis, notum morphogenesis and dorso-central (DC) mechanosensory bristle emergence. The last two processes depend on Pannier (Pnr), a GATA-type TF, which directly activates achaete-scute (ac-sc) proneural genes transcription singly, and represses it in presence of its FOG partner U-shaped (Ush). Clonal analysis in vivo showed that Med1, Med15 and Med19, along with Med12/13 subunits of the detachable "CDK8" module of the MED, are critical for ac-sc activation in a cell-autonomous manner, suggesting functional interactions with Pnr. Interestingly, CycC and Cdk8 subunits from CDK8 module are not involved in ac-sc activation, but are required to ensure ac-sc inhibition in surrounding cells, underscoring the diversity of MED subunits functions in vivo. Moreover, we show that Med19 binds physically to Pnr. Thus, Med19 might be the anchor point by which Pnr recruits the MED at Pnr-activated genes. Furthermore, the FOG factor U-shaped inhibits Med19-Pannier interaction by heterodimerizing with Pannier. Thus, the competition for Pnr binding between Med19 (coactivator) and Ush (corepressor) could be responsible for the antagonistic roles of Pnr on the transcription of its target genes. Interestingly, Med19 is also required for transactivation by another GATA factor: Serpent (Srp, cf. Gobert et al. , 2010). Here we show that Med19 also interacts physically with Srp, suggesting that Med19 could be a general cofactor of GATAs in drosophila. On the other hand, Med1 showed no affinity for Drosophila GATAs (contrary to vertebrate Med1), raising questions about the way MED-TF interactions are acquired and maintained, or not, during evolution. This work highlights the interplay between Med19, GATA-Pnr and FOG-Ush, allowing a mechanistic understanding of Pnr actions as both an activator and a repressor of gene transcription. This PhD thesis is an important step towards appreciating how combinatorial codes of TFs are integrated by the MED to regulate gene transcription during development
Talvik, Gertrud. "Transcription regulation in Plasmodium falciparum : functional characterisation of general transcription factor IIB". Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20616.
Pełny tekst źródłaShah, Sheila Marie Alojipan. "Studies on RNA polymerase III transcription : Structural organization of transcription factor IIIb /". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2001. http://wwwlib.umi.com/cr/ucsd/fullcit?p3025949.
Pełny tekst źródłaLi, Yuxin. "The DEC1 transcription factor : oncogenic involvement and molecular mechanisms on transcription regulation /". View online ; access limited to URI, 2003. http://0-wwwlib.umi.com.helin.uri.edu/dissertations/dlnow/3115632.
Pełny tekst źródłaJohansson, Kajsa. "Transcription of Historical Encrypted Manuscripts : Evaluation of an automatic interactive transcription tool". Thesis, Uppsala universitet, Institutionen för lingvistik och filologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-385254.
Pełny tekst źródłaSydow, Jasmin F. "Structural basis of transcription". Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-107071.
Pełny tekst źródłaMin, Mi-Kyung. "Baculovirus vector transcription analyses". Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279873.
Pełny tekst źródłaRennick, L. J. "Transcription attenuation in morbilliviruses". Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403206.
Pełny tekst źródłaHennigan, Aidan Noel. "Transcription in Methanococcus vannielii /". The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487841975356207.
Pełny tekst źródłaAn, Sungwhan. "Mechanism of coronavirus transcription /". Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.
Pełny tekst źródłaFerrara, Giovanni Antonio. "Studies of transcriptional regulation by the vitamin D3 receptor and cAMP-responsive transcription factors". Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69734.
Pełny tekst źródłaKiosses, Theodore. "DNA binding specificity and transcriptional regulation of Six4 : a myotonic dystrophy associated transcription factor". Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/3948.
Pełny tekst źródłaRheinheimer, Brenna Ann. "Alternative Transcription Of The SLIT2/Mir-218-1 Transcriptional Axis Mediates Pancreatic Cancer Invasion". Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/605118.
Pełny tekst źródłaSmith, Richard LeRoy. "Cis-regulatory Sequence and Co-regulatory Transcription Factor Functions in ERα-Mediated Transcriptional Repression". BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/2261.
Pełny tekst źródłaChery, Alicia. "Rôle de la transcription pervasive antisens chez Saccharomyces cerevisiae dans la régulation de l'expression des gènes". Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066191/document.
Pełny tekst źródłaIn the cell, gene expression is finely tuned and is submitted to different quality-controls. Gene are regulated at different expression levels in order to guarantee a proper synthesis of functional products, and to ensure an optimal adaptation to environmental changes. In particular, transcriptional regulations are critical for gene expression level and kinetics.Pervasive transcription, defined as a generalized non-coding and unstable transcription, was discovered in the yeast Saccharomyces cerevisiae. Although its regulatory potential was punctually shown, the question of its global functionality still remained. During my PhD, I could show the existence of numerous transcriptional interference mechanisms involved in the co-regulation of a group of genes between exponential phase and quiescence. Indeed, non-coding transcription in antisense to genes promoter leads to its repression in conditions where they have to be switched off. The repression mechanism is allowed by chromatin modifications.Hence, budding yeast that lacks RNA interference machinery has developed a fine regulation system using pervasive transcription
Qingquan, Liu. "Investigating the mechanisms of growth factor independence-1 (Gfi-1)-mediated transcriptional repression of p21Cip1 and MBP". Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1241726388.
Pełny tekst źródłaTypescript. "Submitted as partial fulfillment of the requirements for The Doctor of Philosophy in Biology." "A dissertation entitled"--at head of title. Title from title page of PDF document. Bibliography: p. 84-97.
Zandvakili, Arya. "The Role of Affinity and Arrangement of Transcription Factor Binding Sites in Determining Hox-regulated Gene Expression Patterns". University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535708748728472.
Pełny tekst źródłaNgondo, Richard Patryk. "Caractérisation du potentiel régulateur du facteur de transcription ZNF143". Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAJ078.
Pełny tekst źródłaNumerous data were suggesting that the transcription factor ZNF143 regulates the expression of thousand of genes. However, nothing was known about the genome wide regulatory networks, biological processes and transcriptional mechanisms involving this factor.For my PhD thesis I was interested in exploring the regulatory potential of the ZNF143 transcription factor in human. The goal of my project was to identify all the genomic targets of this factor and functionally characterize this ZNF143-DNA interactome. The results I obtained allowed us to identify more than 3000 genes targeted by ZNF143, mainly involved in biological processes linked to cell proliferation. My work also led us to discover new transcriptional mechanisms involving ZNF143. We demonstrated that the transcription factors ZNF143, THAP11 and Notch1 modulate the expression of a common set f gene via overlapping DNA binding sites. Moreover, we also showed that ZNF143 in essential for the divergent expression of genes from bidirectional promoters and that its expression is regulated through auto-regulatory feedback loop
MacKinnon-Roy, Christine. "The role of transcription elongation factor IIS in transcription-coupled nucleotide excision repair". Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28454.
Pełny tekst źródłaBarthel, Kristen Kara Bjorkman. "Mammalian strategies to regulate transcription: Transcription factor sumoylation and cis-regulatory region identification". Connect to online resource, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3284477.
Pełny tekst źródłaTrevett, Julie A. "Teacher-transcription and self-transcription as aids for teaching and learning jazz improvisation". Thesis, University of Exeter, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421583.
Pełny tekst źródłaRoberts, Karen. "Regulation of melanocyte-specific transcription by the transcription factors BRN-2 and microphthalmia". Thesis, Institute of Cancer Research (University Of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286144.
Pełny tekst źródłaBriand, Jean-Baptiste. "Etude du contrôle de la transcription envahissante par la terminaison de la transcription". Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112079/document.
Pełny tekst źródłaTranscription termination is essential, both for the 3’ end formation of functional transcripts and to avoid transcriptional interference between adjacent transcription units. This is particularly important in a compact genome such as S. cerevisiae. Termination is also one of the main strategies used by the cell to control and limit the “pervasive” or “hidden” transcription. In S. cerevisiae, RNA pol II is responsible for the transcription of the mRNAs and numerous non-coding RNA families such as the sn(o)RNAs and the CUTs (Cryptic Unstable Transcripts). CUTs represent a large fraction of the “pervasive” or “hidden” transcription. There are two canonical transcription termination pathways for this RNA polymerase. They involve the cleavage and polyadenylation complex (CPF-CF), in particular for the mRNAs termination, or the NNS complex for sn(o)RNAs and CUTs termination. During my thesis I studied two aspects or the transcription termination: 1) the motifs involved in the NNS complex recruitment on RNA and 2) the identification and the characterization of a new termination pathway by Rap1. CPF-CF and NNS complex are both recruited on the nascent transcript and on the RNA pol II. The NNS complex binds the RNA through its subunits Nrd1 and Nab3 which recognize specific motifs. Nonetheless, even if these motif sequences are now known, their presence does not elicit the certain identification of NNS dependent terminators. To clarify the NNS dependent terminator structure and the organization of the motifs bound by Nrd1 and Nab3 I looked for the sequences involved in a specific CUT termination doing a random mutagenesis experiment and I identified by SELEX the Nrd1-Nab3 dimer optimal binding motifs. A second part of my thesis concerns the characterization of a new transcription termination pathway dependent on the Rap1 factor. Rap1 is important for the telomere structure and it is also a transcription factor that targets hundred of promoters. It activates or represses transcription initiation recruiting chromatin remodeling complexes on the targeted promoters. Surprisingly, the Rap1 binding motifs have been identified among sequences eliciting termination isolated in the laboratory. My work has led to the characterization of the termination mechanism by Rap1 and distinguished this pathway from the two canonical pathways. This factor, bound to DNA, acts as a barrier blocking the RNA pol II progression by a road-block mechanism. These arrested polymerases are targeted by a pathway responsible for the elimination of RNA pol II blocked by DNA damages, implying their ubiquitination and probably their degradation by the proteasome. The released RNAs are polyadenylated by the poly(A) polymerase Trf4 and degraded by the nuclear exosome. This termination mechanism is used in a natural context since I identified S. cerevisiae endogenous transcripts terminated by this pathway. We propose that the Rap1 termination contributes to the pervasive transcription control. This factor could elicit, on its bound promoters, a double function of both transcription factor and protection of these promoters against transcriptional interference
Burton, Elliot N. "Functional Consequences of mtDNA Methylation on Mitochondrial Transcription Factor Binding and Transcription Initiation". VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4185.
Pełny tekst źródłaEustis, Robyn Lynn. "The Role of Pyrococcus furiosus Transcription Factor E in Transcription Iniitiation". PDXScholar, 2015. https://pdxscholar.library.pdx.edu/open_access_etds/2522.
Pełny tekst źródłaPalagi, Alexandre. "Découverte et analyse d’inactivateurs de transcription chez la Drosophile agissant comme amplificateurs dans différents contextes cellulaires". Thesis, Université Côte d'Azur (ComUE), 2018. http://www.theses.fr/2018AZUR4006.
Pełny tekst źródłaA major challenge in biology is to understand how complex gene expression patterns in organismal development are encoded in the genome. While transcriptional enhancers have been studied extensively, few transcriptional silencers have been identified and they remain poorly understood. Here we used a novel strategy to screen hundreds of sequences for tissue-specific silencer activity in whole Drosophila embryos. Strikingly, 100% of the tested elements that we found to act as transcriptional silencers were also active enhancers in other cellular contexts. These elements were enriched in highly occupied target (HOT) region overlap (Roy et al., 2010) and specific transcription factor (TF) motif combinations. CRM bifunctionality complicates the understanding of how gene regulation is specified in the genome and how it is read out differently in different cell types. Our results challenge the common practice of treating elements with enhancer activity identified in one cell type as serving exclusively activating roles in the organism and suggest that thousands or more bifunctional CRMs remain to be discovered in Drosophila and perhaps 104-105 in human (Heintzman et al., 2009). Characterization of bifunctional elements should aid in investigations of how precise gene expression patterns are encoded in the genome
Greberg, Maria Hellqvist. "Cloning and characterization of FREACs, human forkhead transcription factors". Göteborg : Dept. of Cell and Molecular Biology, Göteborg University, 1997. http://catalog.hathitrust.org/api/volumes/oclc/39751934.html.
Pełny tekst źródłaGHNEIM, NADA. "Relations entre les codes de l'oral et de l'écrit : Contraintes et ambiguïtés". Grenoble 3, 1997. http://www.theses.fr/1997GRE39023.
Pełny tekst źródłaThe aim of this thesis is to study the bidrectionnal relations between the writing and the oral codes. The material is an orthographic-phonetic transcription grammar toph (letter-to-sound), and its inverse grammar of phonetic-orthographic transcription phot (sound-to-letter). The formalism of the grammar toph was extended in order to enlarge its field of coverage of the language. Different tools of toph grammars logical analysis were developed in order to trace and modify the grammar to insure the consistency between the rules. A quantitative analysis primitive was constructed in order to validate the grammars' adequacy to the corpora from which they were induced. The inversion of a toph grammar in a phot grammar arose problematics which were formally defined to give a linguistic interpretation of the inversion of the letter-to-sound rules. It is shown that contextual constraints similar in nature to the linguistic constraints and introduced to the french toph grammar, could be transliterated in phot grammar, and that it is therefore possible to limit the multiple homophonic solutions issued from this process, which prevent the production of linguistically aberrant solutions. Finally, was built a method and tools to study a corpus of orthographically deviant words, the orthotel corpus. The results of this treatment, which corroborate the socio-linguistical typology proposed in literature, allow to consider several spelling correction methods based on real human productions
Apostolov, Apostol. "Studying the posttranslational modifications of transcription factor Ikaros and their role in its function". Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00923158.
Pełny tekst źródłaLiu, Xun. "Transcription-dependent and transcription-independent functions of the classical progesterone receptor in Xenopus ovaries". Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26700.
Pełny tekst źródłaWu, Ming-Hsiao. "Temperature Dependent Transcription Initiation in Archaea: Interplay between Transcription Factor B and Promoter Sequence". PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/2021.
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