Artykuły w czasopismach: „The Sentry Project Report”

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Hamer, Jenny, Celene Gonzalez i Garrison W. Cottrell. "The “A Day in the Life” Project: A Preliminary Report". Journal of Vision 19, nr 10 (6.09.2019): 60c. http://dx.doi.org/10.1167/19.10.60c.

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Nugraha, Yogi Adha, Muhammad Rizal Alfandhani, Ratnanto Aditiarno i Candra Mecca Sufyana. "PERANCANGAN SISTEM INFORMASI AKUNTANSI PENGELUARAN KAS ATAS BIAYA PERJALANAN DINAS DI SENTRA WYATA GUNA BANDUNG". Jurnal Indonesia : Manajemen Informatika dan Komunikasi 4, nr 3 (10.09.2023): 1714–22. http://dx.doi.org/10.35870/jimik.v4i3.364.

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A technical implementation unit of the Ministry of Social Affairs' Directorate General for Social Rehabilitation, Sentra Wyata Guna Bandung is involved in the social sector, which includes disaster response and other humanitarian efforts in various parts of Indonesia. A cash disbursement system is one of Sentra Wyata Guna Bandung's accounting methods. Where in this company's cash disbursement system does it meet the head office's operational requirements? The activities of officers on business trips or assignments as duty obligations at the Wyata Guna Sentra take place outside of the area where work operations are carried out. It is possible to say that business travel activities occur quite frequently, which results in frequent cash transfers for business travel expenses. One fact emerged from the study's findings: the manual nature of the cash disbursement report processing meant that official travel cash disbursement reports were susceptible to loss and error. calculation: the goal of this research for the final project is to learn about the use of a cash disbursement accounting system for official travel expenses and to learn about reports of cash disbursements on web-based computerized business trips.

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de la Rua, E. R., J. C. Pastor, I. Fernandez, M. R. Sanabria, J. Garcia-Arumi, V. Martinez-Castillo, R. Coco, L. Manzanas i I. Miranda. "Non-complicated retinal detachment management: variations in 4 years. Retina 1 project; report 1". British Journal of Ophthalmology 92, nr 4 (22.01.2008): 523–25. http://dx.doi.org/10.1136/bjo.2007.127688.

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Akbar, Gilang Nur, Gilang Ramadhan, Muthmainnah i Seliwati. "Manajemen Sistem Informasi Akuntansi Penjualan Menggunakan Microsoft Visual Studio 2019 di Café More Wyata Guna Bandung". Jurnal JTIK (Jurnal Teknologi Informasi dan Komunikasi) 6, nr 4 (15.05.2022): 616–23. http://dx.doi.org/10.35870/jtik.v6i4.619.

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Café more is a business project of the Indonesian Ministry of Social Affairs through the Center for Social Rehabilitation of Persons with Sensory Disabilities Netra Wyata Guna Bandung. The author's purpose of conducting this research is to compile a management design for sales accounting information system using Microsoft Visual Studio 2019 and database MySQL. In this study, the authors use qualitative methods with interview data collection methods, literature study data or observation. And also the system development method used is the prototype. From the results of this study, a problem was found, namely the processing of cafe more sales data reports is still manual so that sales reports are still irregular and prone to errors in making the report and the information presented is less accurate. With this sales information system management design, the author hopes to simplify the work of employees in managing sales data and sales reports quickly and accurately.

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Valberg, A., i P. Fosse. "Vision with Age-Related Macular Degeneration". Perception 26, nr 1_suppl (sierpień 1997): 21. http://dx.doi.org/10.1068/v970010.

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Visual Science at the Norwegian University of Science and Technology (NUST) includes activities in visual psychophysics and electrophysiology, clinical tests of vision, and low vision. In recent years the Tambartun National Resource Centre for the Visually Impaired, in cooperation with NUST, has been encouraging applied projects aimed at improving the quality of life of people with low vision. One such project, headed by Per Fosse, is devoted to the study of the visual capacity of elderly with age-related macular degeneration. Systematic assessments are made of acuity, contrast sensitivity (CS), colour vision, visual field, dark adaptation, and optimal illumination levels for reading and orientation. We report on some preliminary results for ten clients, which is about half the number of anticipated participants in the project. The differences in performance of the individuals that we have seen so far are large, particularly concerning their lighting requirements. Some clients preferred a relatively restricted optimum range of illumination, while others required very high levels. All clients profited from these extensive tests in orientation in real-life settings and in reading. Different CS tests and acuity measures have been compared in the course of the study, and some of these data are also presented.

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Pastor, J. C., I. Fernandez, E. R. de la Rua, R. Coco, M. R. S. R. Colmenares, D. S. Chicharro, R. Martinho i in. "Surgical outcomes for primary rhegmatogenous retinal detachments in phakic and pseudophakic patients: the Retina 1 Project--report 2". British Journal of Ophthalmology 92, nr 3 (26.02.2008): 378–82. http://dx.doi.org/10.1136/bjo.2007.129437.

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Pierce, Jennifer, Afton L. Hassett, Rick E. Harris, Jenna Goesling i Chad M. Brummett. "4385 The Pain and Social Experiences Project: Understanding the role of interpersonal trauma in pain". Journal of Clinical and Translational Science 4, s1 (czerwiec 2020): 113. http://dx.doi.org/10.1017/cts.2020.345.

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OBJECTIVES/GOALS: Traumatic interpersonal experiences are associated with higher rates of chronic pain, increased pain severity and poorer functioning. The objective of this ongoing project is to obtain prevalence rates for various forms of interpersonal trauma among individuals with chronic pain, and to explore the potential mediating effect of heightened sensory and social sensitivity on the experience of pain. METHODS/STUDY POPULATION: Patients at Michigan Medicine between the ages of 18 and 65 complete an online survey. Patients are being recruited through a tertiary-care, outpatient pain clinic, as well as through an online health research portal. We aim to recruit 700 participants; we currently have 59.6% of our goal (n = 417). Participants also have the option to be included in a registry from which we can recruit for future studies. Approximately 85% of our participants have agreed to be in the registry. RESULTS/ANTICIPATED RESULTS: Preliminary data show that, of the 263 (63.4%) participants for whom data on chronic pain is available, 167 (63.5%) report chronic or persistent pain over the previous 3 months. Of these, 54% reported some form of childhood abuse or neglect. Approximately 41% reported four or more adverse childhood experiences. Additionally, of the 122 participants (73%) who were in a current romantic relationship, 20% reported some form of physical violence victimization from their romantic partner. We anticipate that interpersonal trauma will be associated with poorer perceptions of social relationships, higher sensory sensitivity, and higher perceived stress. DISCUSSION/SIGNIFICANCE OF IMPACT: The PASE Project parent study will be used to better understand prevalence rates for various forms of interpersonal trauma in our chronic pain population. Future analyses and studies will explore alternative pathways linking interpersonal trauma to the experience of pain through sensory and social sensitivity, which will inform interventions aimed at reducing pain among patients with a history of trauma.

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Cox, Diane L. "Wheelchair Needs for Children and Young People: A Review". British Journal of Occupational Therapy 66, nr 5 (maj 2003): 219–23. http://dx.doi.org/10.1177/030802260306600506.

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This work was commissioned by a charity, the Physical Disability and Sensory Impairment Forum, owing to local parental concerns relating to the assessment for and provision of mobility equipment. The project was set up as a preliminary investigation to consider those concerns. A literature review was carried out in order to establish current practice in the National Health Service wheelchair service in England, the role of the wheelchair in children's mobility, the wheelchair and seating needs of children and the met and unmet need. A questionnaire was distributed to children and their parents to gain their views. The response rate was disappointingly poor and, therefore, the results are not presented. However, the full report is available from the author.

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Pizzi, Laura T., Michael Waisbourd, Lisa Hark, Harjeet Sembhi, Paul Lee, John E. Crews, Jinan B. Saaddine, Deon Steele i L. Jay Katz. "Costs of a community-based glaucoma detection programme: analysis of the Philadelphia Glaucoma Detection and Treatment Project". British Journal of Ophthalmology 102, nr 2 (27.06.2017): 225–32. http://dx.doi.org/10.1136/bjophthalmol-2016-310078.

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BackgroundGlaucoma is the foremost cause of irreversible blindness, and more than 50% of cases remain undiagnosed. Our objective was to report the costs of a glaucoma detection programme operationalised through Philadelphia community centres.MethodsThe analysis was performed using a healthcare system perspective in 2013 US dollars. Costs of examination and educational workshops were captured. Measures were total programme costs, cost/case of glaucoma detected and cost/case of any ocular disease detected (including glaucoma). Diagnoses are reported at the individual level (therefore representing a diagnosis made in one or both eyes). Staff time was captured during site visits to 15 of 43 sites and included time to deliver examinations and workshops, supervision, training and travel. Staff time was converted to costs by applying wage and fringe benefit costs from the US Bureau of Labor Statistics. Non-staff costs (equipment and mileage) were collected using study logs. Participants with previously diagnosed glaucoma were excluded.Results1649 participants were examined. Mean total per-participant examination time was 56 min (SD 4). Mean total examination cost/participant was $139. The cost/case of glaucoma newly identified (open-angle glaucoma, angle-closure glaucoma, glaucoma suspect, or primary angle closure) was $420 and cost/case for any ocular disease identified was $273.ConclusionGlaucoma examinations delivered through this programme provided significant health benefit to hard-to-reach communities. On a per-person basis, examinations were fairly low cost, though opportunities exist to improve efficiency. Findings serve as an important benchmark for planning future community-based glaucoma examination programmes.

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IWANIUK, ANDREW N., JANELLE M. P. PAKAN, CRISTIÁN GUTIÉRREZ-IBÁÑEZ i DOUGLAS R. WYLIE. "Expression of calcium-binding proteins in cerebellar- and inferior olivary-projecting neurons in the nucleus lentiformis mesencephali of pigeons". Visual Neuroscience 26, nr 3 (maj 2009): 341–47. http://dx.doi.org/10.1017/s0952523809090087.

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AbstractIn the avian brain, the optokinetic response is controlled by two retinal-recipient nuclei: the nucleus of the basal optic root (nBOR) of the accessory optic system and the pretectal nucleus lentiformis mesencephali (LM). Although considered sister nuclei because of their similar response properties and function, there are both similarities and differences with respect to efferent projections and neurochemistry. Both nBOR and LM project to the cerebellum (Cb) directly as mossy fibers but also indirectly via the inferior olive (IO). In a previous report, we showed that the cerebellar- and inferior olivary-projecting neurons in nBOR of pigeons differentially express the calcium-binding proteins calretinin (CR) and parvalbumin (PV). Both CR and PV are expressed in the somata of LM neurons, although the latter is not as prevalent, and whether expression of CR and PV reflects cerebellar and IO projections is not known. In this report, by combining retrograde neuronal tracing from the Cb and IO with fluorescent immunohistochemistry, we examined the expression of these calcium-binding proteins in the pigeon LM. Half (52%) of the cerebellar-projecting neurons were CR+ve, but only 15% were PV+ve. Almost all (>95%) these PV+ve cells also expressed CR. In contrast, few of the IO-projecting neurons expressed CR or PV (≤5%). This is strikingly similar to what we observed in nBOR and reveals that calcium-binding protein expression is concordant with projection patterns in two nuclei that share similar functions.

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Zhang, Amanda, Kristen Wroblewski, Martha McClintock, Louise Hawkley i Jayant Pinto. "VIDEO CALLING REDUCES LONELINESS FOR HEARING IMPAIRED OLDER US ADULTS DURING THE COVID-19 PANDEMIC". Innovation in Aging 6, Supplement_1 (1.11.2022): 31–32. http://dx.doi.org/10.1093/geroni/igac059.117.

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Abstract Older adults with hearing impairment (HI) experience communication challenges that may result in increased loneliness exacerbated by social distancing during COVID-19. Video-calling may mitigate isolation-related loneliness. We addressed this hypothesis in the National Social Life, Health, and Aging Project (NSHAP), a longitudinal, nationally representative study of home-dwelling older US adults. Hearing ability was determined by interviewer-rating and loneliness/video-calling use by self-report. Fewer older adults (≥55 years) with HI (n=221) reported regular use of video-calling during the pandemic vs. those without HI (n=2337) (14% vs. 30%, p<0.001). Older adults with HI reported greater loneliness during COVID-19 (p=0.031), with video calls mitigating this relationship through a dose-dependent effect in adjusted analyses (interaction p=0.001). Video-calling decreases HI-related loneliness, despite potential barriers those with sensory impairment face using this technology. Promoting greater adoption of video-calling could be a strategy to protect against HI-related loneliness in aging.

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Sábado, Javier, Anna Casanovas, Olga Tarabal, Marta Hereu, Lídia Piedrafita, Jordi Calderó i Josep E. Esquerda. "Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis". BioMed Research International 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/852163.

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Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive neurodegenerative disease affecting upper and lower motoneurons (MNs). Although the motor phenotype is a hallmark for ALS, there is increasing evidence that systems other than the efferent MN system can be involved. Mutations ofsuperoxide dismutase 1(SOD1) gene cause a proportion of familial forms of this disease. Misfolding and aggregation of mutant SOD1 exert neurotoxicity in a noncell autonomous manner, as evidenced in studies using transgenic mouse models. Here, we used theSOD1G93Amouse model for ALS to detect, by means of conformational-specific anti-SOD1 antibodies, whether misfolded SOD1-mediated neurotoxicity extended to neuronal types other than MNs. We report that large dorsal root ganglion (DRG) proprioceptive neurons accumulate misfolded SOD1 and suffer a degenerative process involving the inflammatory recruitment of macrophagic cells. Degenerating sensory axons were also detected in association with activated microglial cells in the spinal cord dorsal horn of diseased animals. As large proprioceptive DRG neurons project monosynaptically to ventral horn MNs, we hypothesise that a prion-like mechanism may be responsible for the transsynaptic propagation of SOD1 misfolding from ventral horn MNs to DRG sensory neurons.

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Changizi, Mark A., i David M. Widders. "Latency Correction Explains the Classical Geometrical Illusions". Perception 31, nr 10 (październik 2002): 1241–62. http://dx.doi.org/10.1068/p3412.

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There is a significant delay between the time when light hits the retina and the time of the consequent percept. It has been hypothesized that the visual system attempts to correct for this latency by generating a percept representative of the way the world probably is at the time the percept is elicited, rather than a percept of the recent past. Here we show that such a ‘perceiving the present’ hypothesis explains a number of classical geometrical illusions: the Hering, Orbison, Müller-Lyer, Double Judd, Poggendorff, Corner, and Upside-down-T illusions. Each stimulus is perceived as it would project in the next moment were the observer moving through the scene the stimulus probably represents. We also examine one general class of predictions made by the hypothesis, and report psychophysical experiments confirming the predictions.

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Goldman, Alyssa, i Jayant Pinto. "NEIGHBORHOOD CHARACTERISTICS AND INEQUALITIES IN SENSORY HEALTH AMONG OLDER ADULTS IN THE UNITED STATES". Innovation in Aging 7, Supplement_1 (1.12.2023): 109. http://dx.doi.org/10.1093/geroni/igad104.0355.

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Abstract Sensory function plays a crucial role in older adults’ navigation of the environment, maintenance of personal safety, and in quality of everyday life. The residential neighborhood context is a significant social determinant of later life health and health disparities, but it has been understudied with respect to sensory function. We consider that residential neighborhoods are key sites of social and economic resources, social engagement, and environmental stimulation that could influence sensory health and inequalities in sensory impairment. We use data from 2,251 older adults who were interviewed at Rounds 1 and 2 of the National Social Life, Health and Aging Project in a series of longitudinal random effects models that examine how self-reported and objectively measured neighborhood characteristics are associated with self-rated vision and hearing. We find that older adults who reside in census tracts with higher levels of concentrated disadvantage report significantly worse self-rated vision and hearing compared with older adults who live in areas with less concentrated disadvantage. Residing in a more densely populated tract, however, is associated with better self-rated hearing. Black and Hispanic older adults’ self-rated hearing benefits significantly more from living in a densely populated tract than does White older adults’ self-rated hearing. In cross-sectional models, higher perceptions of neighborhood safety and social ties are associated with better self-rated vision. Our findings prompt a more nuanced understanding of how the social environment affects sensory health and highlight sensory function as a potential underexplored pathway through which neighborhood characteristics shape health disparities in later life.

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Valente, João, Leonor Godinho, Cristina Pintado, Cátia Baptista, Veronika Kozlova, Luís Marques, Ana Fred i Hugo Plácido da Silva. "Neuroorganoleptics: Organoleptic Testing Based on Psychophysiological Sensing". Foods 10, nr 9 (24.08.2021): 1974. http://dx.doi.org/10.3390/foods10091974.

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There is an increasing interest, in consumer behaviour research related to food and beverage, in taking a step further from the traditional self-report questionnaires and organoleptic properties assessment. With the growing availability of psychophysiological data acquisition devices, and advancements in the study of the underlying signal sources seeking affective state assessment, the use of psychophysiological data analysis is a natural evolution in organoleptic testing. In this paper we propose a protocol for what can be defined as neuroorganoleptic analysis, a method that combines traditional approaches with psychophysiological data acquired during sensory testing. Our protocol was applied to a case study project named MobFood, where four samples of food were tested by a total of 83 participants, using preference and acceptance tasks, across three different sessions. Best practices and lessons learned regarding the laboratory setting and the acquisition of psychophysiological data were derived from this case study, which are herein described. Preliminary results show that certain Heart Rate Variability (HRV) features have a strong correlation with the preferences self-reported by the participants.

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Benardete, Ethan A., Ehud Kaplan i Bruce W. Knight. "Contrast gain control in the primate retina: P cells are not X-like, some M cells are". Visual Neuroscience 8, nr 5 (maj 1992): 483–86. http://dx.doi.org/10.1017/s0952523800004995.

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AbstractPrimate retinal ganglion cells that project to the magnocellular layers of the lateral geniculate nucleus (M) are much more sensitive to luminance contrast than those ganglion cells projecting to the parvocellular layers (P). We now report that increasing contrast modifies the temporal-frequency response of M cells, but not of P cells. With rising contrast, the M cells' responses to sinusoidal stimuli show an increasing attenuation at low temporal frequencies while the P cells' responses scale uniformly. The characteristic features of M-cell dynamics are well described by a model originally developed for the X and Y cells of the cat, where the hypothesized nonlinear feedback mechanism responsible for this behavior has been termed the contrast gain control (Shapley & Victor, 1978, 1981; Victor, 1987, 1988). These data provide further physiological evidence that the M-cell pathway differs from the P-cell pathway with regard to the functional elements in the retina. Furthermore, the similarity in dynamics between primate M cells and cat X and Y retinal ganglion cells suggests the possibility that P cells, being different from either group, are a primate specialization not found in the retinae of lower mammals.

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Stephen, Jennifer M., Mark A. Toleman, Timothy R. Walsh i Ronald N. Jones. "Salmonella bloodstream infections: report from the SENTRY Antimicrobial Surveillance Program (1997–2001)". International Journal of Antimicrobial Agents 22, nr 4 (październik 2003): 395–405. http://dx.doi.org/10.1016/s0924-8579(03)00063-3.

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Meredith, M. Alex, Mark T. Wallace i H. Ruth Clemo. "Do the Different Sensory Areas Within the Cat Anterior Ectosylvian Sulcal Cortex Collectively Represent a Network Multisensory Hub?" Multisensory Research 31, nr 8 (2018): 793–823. http://dx.doi.org/10.1163/22134808-20181316.

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Abstract Current theory supports that the numerous functional areas of the cerebral cortex are organized and function as a network. Using connectional databases and computational approaches, the cerebral network has been demonstrated to exhibit a hierarchical structure composed of areas, clusters and, ultimately, hubs. Hubs are highly connected, higher-order regions that also facilitate communication between different sensory modalities. One computationally identified network hub is the visual area of the Anterior Ectosylvian Sulcal cortex (AESc) of the cat. The Anterior Ectosylvian Visual area (AEV) is but one component of the AESc since the latter also includes the auditory (Field of the Anterior Ectosylvian Sulcus — FAES) and somatosensory (Fourth somatosensory representation — SIV) areas. To better understand the nature of cortical network hubs, the present report reviews the biological features of the AESc. Within the AESc, each area has extensive external cortical connections as well as among one another. Each of these core representations is separated by a transition zone characterized by bimodal neurons that share sensory properties of both adjoining core areas. Finally, core and transition zones are underlain by a continuous sheet of layer 5 neurons that project to common output structures. Altogether, these shared properties suggest that the collective AESc region represents a multiple sensory/multisensory cortical network hub. Ultimately, such an interconnected, composite structure adds complexity and biological detail to the understanding of cortical network hubs and their function in cortical processing.

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Kotaka, Masahito, Takeharu Yamanaka, Takayuki Yoshino, Dai Manaka, Tetsuya Eto, Junichi Hasegawa, Akinori Takagane i in. "Safety data from the phase III Japanese ACHIEVE trial: part of an international, prospective, planned pooled analysis of six phase III trials comparing 3 versus 6 months of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer". ESMO Open 3, nr 3 (kwiecień 2018): e000354. http://dx.doi.org/10.1136/esmoopen-2018-000354.

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BackgroundThe International Duration Evaluation of Adjuvant chemotherapy project investigated whether a shorter duration of oxaliplatin-based adjuvant chemotherapy was as effective as 6 months of identical chemotherapy for resected stage III colon cancer. As part of this project, we report safety data from the Japanese ACHIEVE study (JFMC47-1202-C3).Patients and methodsACHIEVE was an open-label, multicentre trial randomising patients with stage III colon cancer to receive 3 m or 6 m of mFOLFOX6/CAPOX after surgery. Choice of regimen was declared before randomisation by a site investigator.ResultsBetween August 2012 and June 2014, 1313 patients were enrolled and, of those, 1277 were analysed for the safety analysis, with 635 in arm 6 (mFOLFOX6, n=158; CAPOX, n=477) and 642 in arm 3 (mFOLFOX6, n=161; CAPOX, n=481). Grade 3 or worse peripheral sensory neuropathy (PSN) developed in 5%/0.6% of patients receiving mFOLFOX6 in arm 6/3 (p=0.019) and 6%/1% of those receiving CAPOX in arm 6/3 (p<0.001). Similarly, grade 2 or worse PSN developed in 36%/11% of patients receiving mFOLFOX6 in arm 6/3 (p<0.001) and 37%/14% of those receiving CAPOX in arm 6/3 (p<0.001). An association between baseline creatinine clearance (CCr) and adverse events (AEs) was found that patients with CAPOX were significantly more likely to develop AEs ≥grade 3 when they had a CCr ≤50 (OR 1.67; p=0.048).ConclusionsWe confirmed in the Japanese population that the shorter duration of adjuvant chemotherapy resulted in a significant reduction of PSN. In patients with CAPOX, renal function was significantly related to severe AEs.Trial registration numberUMIN000008543, Results.

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Briggs, A., K. Logan i P. Alberto. "Achieving Educational Change through Technical Assistance". Journal of Visual Impairment & Blindness 88, nr 4 (lipiec 1994): 310–16. http://dx.doi.org/10.1177/0145482x9408800407.

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This article reports on a survey of recipients of 51 technical assistance projects in 18 states and territories provided by the Teaching Research Assistance to Children Experiencing Sensory Impairments project. On the basis of the respondents’ assessments of factors that result in the most effective provision of technical assistance by consultants in educational settings, the authors present a systematic approach to the achievement of desired individual, programmatic, and systemwide changes through technical assistance.

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Dar, Saba Nadeem, Nehzat Zehra, Fatima Javed, Minahil Fatima, Sana Saleem, Kiran Firdous, Anum Firdous i Aqsa Nadeem. "DEVELOPMENT OF COST-EFFECTIVE AND NUTRITIOUS SNACK BAR FROM LOCALLY AVAILABLE INGREDIENTS". International Journal of Pharmacy & Integrated Health Sciences 4, nr 2 (1.09.2023): 112–17. http://dx.doi.org/10.56536/ijpihs.v4i2.101.

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Background: The development of ready-to-eat meal replacement bars that provide health benefits, such as low-calorie content and increased levels of protein, fiber, and antioxidants, is essential given current consumer trends. Objectives: This project aimed to evaluate the acceptability of a snack bar made with local ingredients. This study aimed to manufacture a snack bar nutritionally enriched with local ingredients such as "roasted black chickpeas", nuts, and underutilized seeds. Methodology: It was an Experimental study. The proximate analysis of the snack bar was performed. At least 30 snack bars were formed, and their sensory qualities were subsequently evaluated by the 40 members of an expert panel using 9 points hedonic scale. Results: The weight of the sample is 40 g and proximate analysis was done. The samples' nutrient content and sensory properties were assessed. According to the proximate analysis report, the snack bar has a dry matter of 83.42%, moisture of 16.58%, crude protein of 16.65%, a crude fiber of 11.72%, ether extract of 31.27%, ash of 3.03%, and nitrogen free extract 37.34%. Conclusion: In conclusion, snack bars can easily be enriched with roasted chickpeas. The proximate analysis of the bar indicated that it was rich in macronutrients. The cost analysis of the bar revealed that by using local ingredients inexpensive healthy snack bars can be produced.

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Mutnick, Alan H., Victoria Enne i Ronald N. Jones. "Linezolid Resistance since 2001: SENTRY Antimicrobial Surveillance Program". Annals of Pharmacotherapy 37, nr 6 (czerwiec 2003): 769–74. http://dx.doi.org/10.1345/aph.1c437.

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BACKGROUND: The oxazolidinone class of antimicrobials has demonstrated remarkable activity against gram-positive cocci. Linezolid has proven to be a first-line therapeutic option for vancomycin-resistant strains. Linezolid clinical trial results and subsequent published case reports cite rare resistance emerging in patients receiving prolonged therapy. OBJECTIVE: To report the initial linezolid-resistant organisms from cases obtained through the SENTRY Antimicrobial Surveillance Program, after screening >40 000 gram-positive cocci without resistance between 1998 and 2000. METHODS: During 2001–2002, 8 resistant strains (from 8 different patients) located in 6 states from 7 different participating SENTRY institutions in the US were identified among bloodstream, respiratory, skin and soft tissue, and urinary tract infection isolates of Enterococcus faecalis, Enterococcus faecium, Staphylococcus epidermidis, and Streptococcus oralis. Resistance was detected by reference broth microdilution methods and confirmed by identical results using Etest (AB BIODISK, Solna, Sweden) and the standardized disk diffusion method. RESULTS: Minimum inhibitory concentration (MIC) and disk diffusion tests showed elevated MICs (≥8 μg/mL) and small inhibitory zone diameters (≤15 mm) for all strains to both linezolid and the investigational oxazolidinone AZD2563. Vancomycin resistance was detected in 2 of the 8 linezolid-resistant strains. All enterococci and the viridans-group streptococcus ( S. oralis) strain showed resistance to erythromycin. E. faecium strains were resistant to penicillins, but susceptible to quinupristin/dalfopristin. Only 3 of the patients had previously received the drug. CONCLUSIONS: Linezolid resistance remains rare, with only 8 isolates among 9833 (0.08%) monitored isolates identified between January 1, 2001, and June 30, 2002. Resistance, however, was no longer limited to enterococci. Clinical laboratories should test linezolid more widely to detect emerging resistance, especially for patients receiving oxazolidinone therapy. Longitudinal surveillance programs are warranted to detect a trend in the development of resistance, determine the molecular mechanism of resistance, and recommend alternative therapies or epidemiologic interventions.

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Lontis, Eugen Romulus, Ken Yoshida i Winnie Jensen. "Non-Invasive Sensory Input Results in Changes in Non-Painful and Painful Sensations in Two Upper-Limb Amputees". Prosthesis 6, nr 1 (19.12.2023): 1–23. http://dx.doi.org/10.3390/prosthesis6010001.

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Designs of active prostheses attempt to compensate for various functional losses following amputation. Integration of sensory feedback with the functional control re-enables sensory interaction with the environment through the prosthetic. Besides the functional and sensory loss, amputation induces anatomical and physiological changes of the sensory neural pathways, both peripherally and centrally, which can lead to phantom limb pain (PLP). Additionally, referred sensation areas (RSAs) likely originating from peripheral nerve sprouting, regeneration, and sensory reinnervation may develop. RSAs might provide a non-invasive access point to sensory neural pathways that project to the lost limb. This paper aims to report on the sensory input features, elicited using non-invasive electrical stimulation of RSAs that over time alleviated PLP in two upper-limb amputees. The distinct features of RSAs and sensation evoked using mechanical and electrical stimuli were characterized for the two participants over a period of 7 and 9 weeks, respectively. Both participants received transradial and transhumeral amputation following traumatic injuries. In one participant, a relatively low but stable number of RSAs provided a large variety of types of evoked phantom hand (PH) sensations. These included non-painful touch, vibration, tingling, stabbing, pressure, warmth/cold as well as the perception of various positions and movements of the phantom hand upon stimulation. Discomforting and painful sensations were induced with both mechanical and electrical stimuli. The other participant had a relatively large number of RSAs which varied over time. Stimulation of the RSAs provided mostly non-painful sensations of touch in the phantom hand. Temporary PLP alleviation and a change in the perception of the phantom hand from a tight to a more open fist were reported by both participants. The specificity of RSAs, dynamics in perception of the sensory input, and the associated alleviation of PLP could be effectively exploited by designs of future active prostheses. As such, techniques for the modulation of the sensory input associated with paradigms from interaction with the environment may add another dimension of protheses towards integrating personalized therapy for PLP.

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Wittich, Walter, Fiona Höbler, Jonathan Jarry i Katherine S. McGilton. "Recommendations for successful sensory screening in older adults with dementia in long-term care: a qualitative environmental scan of Canadian specialists". BMJ Open 8, nr 1 (styczeń 2018): e019451. http://dx.doi.org/10.1136/bmjopen-2017-019451.

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ObjectivesThis study aimed to identify screening tools, technologies and strategies that vision and hearing care specialists recommend to front-line healthcare professionals for the screening of older adults in long-term care homes who have dementia.SettingAn environmental scan of healthcare professionals took place via telephone interviews between December 2015 and March 2016. All interviews were audio recorded, transcribed, proofed for accuracy, and their contents thematically analysed by two members of the research team.ParticipantsA convenience sample of 11 professionals from across Canada specialising in the fields of vision and hearing healthcare and technology for older adults with cognitive impairment were included in the study.Outcome measuresAs part of a larger mixed-methods project, this qualitative study used semistructured interviews and their subsequent content analysis.ResultsFollowing a two-step content analysis of interview data, coded citations were grouped into three main categories: (1) barriers, (2) facilitators and (3) tools and strategies that do or do not work for sensory screening of older adults with dementia. We report on the information offered by participants within each of these themes, along with a summary of tools and strategies that work for screening older adults with dementia.ConclusionsRecommendations from sensory specialists to nurses working in long-term care included the need for improved interprofessional communication and collaboration, as well as flexibility, additional time and strategic use of clinical intuition and ingenuity. These suggestions at times contradicted the realities of service provision or the need for standardised and validated measures.

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Cannon, Sheila, Thomas Connelly, Susan DeSanto-Madeya, Jacqueline Fawcett, Laura L. Hayman, Kathleen Hickson i Haeok Lee. "Project Report". Journal of Family Nursing 17, nr 2 (29.04.2011): 270–71. http://dx.doi.org/10.1177/1074840711404160.

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Grundmann, Christoffer H. "Project Report". Mission Studies 13, nr 1 (1996): 335–37. http://dx.doi.org/10.1163/157338396x00221.

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Best, K. ‐H, i G. Altmann. "Project report". Journal of Quantitative Linguistics 3, nr 1 (kwiecień 1996): 85–88. http://dx.doi.org/10.1080/09296179608590067.

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Kolar, Miriam A., Doyuen Ko i Sungyoung Kim. "Preserving Human Perspectives in Cultural Heritage Acoustics: Distance Cues and Proxemics in Aural Heritage Fieldwork". Acoustics 3, nr 1 (3.03.2021): 156–76. http://dx.doi.org/10.3390/acoustics3010012.

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We examine the praxis implications of our working definition of aural heritage: spatial acoustics as physically experienced by humans in cultural contexts; aligned with the aims of anthropological archaeology (the study of human life from materials). Here we report on human-centered acoustical data collection strategies from our project “Digital Preservation and Access to Aural Heritage via a Scalable, Extensible Method,” supported by the National Endowment for the Humanities (NEH) in the USA. The documentation and accurate translation of human sensory perspectives is fundamental to the ecological validity of cultural heritage fieldwork and the preservation of heritage acoustics. Auditory distance cues, which enable and constrain sonic communication, relate to proxemics, contextualized understandings of distance relationships that are fundamental to human social interactions. We propose that source–receiver locations in aural heritage measurements should be selected to represent a comprehensive range of proxemics according to site-contextualized spatial-use scenarios, and we identify and compare acoustical metrics for auditory distance cues from acoustical fieldwork we conducted using this strategy in three contrasting case-study heritage sites. This conceptual shift from architectural acoustical sampling to aural heritage sampling prioritizes culturally and physically plausible human auditory/sound-sensing perspectives and relates them to spatial proxemics as scaled architecturally.

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Bartolo, Michelangelo, Domenico Intiso i Chiara Zucchella. "Neurorehabilitation in brain tumours: evidences and suggestions for spreading of knowledge and research implementation". Current Opinion in Oncology 35, nr 6 (14.09.2023): 543–49. http://dx.doi.org/10.1097/cco.0000000000000999.

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Purpose of review The last few decades have seen an increase in life expectancy in brain tumour patients; however, many patients report sensory-motor and cognitive disabilities due to the tumour itself, but also to the effect of anticancer treatments (surgery, radiotherapy, chemotherapy), supportive treatments, as well as individual patient factors. This review outlines the principles on which to base neurorehabilitation treatments, with the aim of stimulating an early rehabilitative management, in order to reduce disability and functional limitation and improve the quality of life of the persons affected by brain tumour. Recent findings Although not definitive, evidences suggest that an early neurorehabilitative evaluation, performed with a multidisciplinary approach, may identify the different functional impairments that can affect people with brain tumour. Furthermore, identifying and classifying the person's level of functioning is useful for designing achievable recovery goals, through the implementation of tailored multidisciplinary rehabilitation programs. The involvement of different professional figures allows to treat all the components (physical, cognitive, psychological and participation) of the person, and to redesign one's life project, lastly improving the quality of life. Summary Overall, the evidences suggest a critical need for the development of this clinical area by spreading the concept of rehabilitation among neuro-oncologists and producing high quality research.

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Sader, Helio S., Ronald N. Jones, Ana C. Gales, Juliana B. Silva i Antonio C. Pignatari. "SENTRY antimicrobial surveillance program report: latin american and brazilian results for 1997 through 2001". Brazilian Journal of Infectious Diseases 8, nr 1 (luty 2004): 25–79. http://dx.doi.org/10.1590/s1413-86702004000100004.

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Toleman, Mark A., Doug Biedenbach, David M. C. Bennett, Ronald N. Jones i Timothy R. Walsh. "Italian metallo-β-lactamases: a national problem? Report from the SENTRY Antimicrobial Surveillance Programme". Journal of Antimicrobial Chemotherapy 55, nr 1 (1.01.2005): 61–70. http://dx.doi.org/10.1093/jac/dkh512.

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Randell, Elizabeth, Melissa Wright, Sarah Milosevic, David Gillespie, Lucy Brookes-Howell, Monica Busse-Morris, Richard Hastings i in. "Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT". Health Technology Assessment 26, nr 29 (czerwiec 2022): 1–140. http://dx.doi.org/10.3310/tqge0020.

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Background Carers report unmet need for occupational therapy services addressing sensory difficulties in autism, yet insufficient evidence exists to recommend a therapeutic approach. Objectives Our aim was to determine the clinical effectiveness and cost-effectiveness of sensory integration therapy for children with autism and sensory difficulties across behavioural, functional and quality-of-life outcomes. Design We carried out a parallel-group randomised controlled trial, incorporating an internal pilot and a process evaluation. Randomisation utilised random permuted blocks. Setting and participants Children were recruited via services and self-referral in Wales and England. Inclusion criteria were having an autism diagnosis, being in mainstream primary education and having definite/probable sensory processing difficulties. Exclusion criteria were having current/previous sensory integration therapy and current applied behaviour analysis therapy. Intervention The intervention was manualised sensory integration therapy delivered over 26 weeks and the comparator was usual care. Outcomes The primary outcome was problem behaviours (determined using the Aberrant Behavior Checklist), including irritability/agitation, at 6 months. Secondary outcomes were adaptive behaviour, functioning and socialisation (using the Vineland Adaptive Behavior Scales); carer stress (measured using the Autism Parenting Stress Index); quality of life (measured using the EuroQol-5 Dimensions and Carer Quality of Life); functional change (according to the Canadian Occupational Performance Measure); sensory processing (determined using the Sensory Processing Measure™ at screening and at 6 months to examine mediation effects); and cost-effectiveness (assessed using the Client Service Receipt Inventory). Every effort was made to ensure that outcome assessors were blind to allocation. Results A total of 138 participants were randomised (n = 69 per group). Usual care was significantly different from the intervention, which was delivered with good fidelity and adherence and minimal contamination, and was associated with no adverse effects. Trial procedures and outcome measures were acceptable. Carers and therapists reported improvement in daily functioning. The primary analysis included 106 participants. There were no significant main effects of the intervention at 6 or 12 months. The adjusted mean difference between groups on the Aberrant Behavior Checklist – irritability at 6 months post randomisation was 0.40 (95% confidence interval –2.33 to 3.14; p = 0.77). Subgroup differences in irritability/agitation at 6 months were observed for sex of child (intervention × female = 6.42, 95% confidence interval 0.00 to 12.85; p = 0.050) and attention deficit hyperactivity disorder (intervention × attention deficit hyperactivity disorder = –6.77, 95% confidence interval –13.55 to –0.01; p = 0.050). There was an effect on carer stress at 6 months by region (intervention × South England = 7.01, 95% confidence interval 0.45 to 13.56; p = 0.04) and other neurodevelopmental/genetic conditions (intervention × neurodevelopmental/genetic condition = –9.53, 95% confidence interval –18.08 to –0.98; p = 0.030). Carer-rated goal performance and satisfaction increased across sessions (p < 0.001), with a mean change of 2.75 (95% confidence interval 2.14 to 3.37) for performance and a mean change of 3.34 (95% confidence interval 2.63 to 4.40) for satisfaction. Health economic evaluation suggests that sensory integration therapy is not cost-effective compared with usual care alone. Limitations Limitations included variability of the intervention setting (i.e. NHS vs. private), delay for some receiving therapy, an error in administration of Vineland Adaptive Behavior Scales and no measurement of comparator arm goal performance. Conclusions The intervention did not demonstrate clinical benefit above standard care. Subgroup effects are hypothesis-generating only. The intervention is likely to be effective for individualised performance goals, although it is unclear whether effects were in addition to standard care or were maintained. Future work Further investigation of subgroup effects is needed. Trial registration This trial is registered as ISRCTN14716440. Funding This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 26, No. 29. See the NIHR Journals Library website for further project information.

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McCormick, Catherine A., Shannon Gallagher, Evan Cantu-Hertzler i Scarlet Woodrick. "Mechanosensory Lateral Line Nerve Projections to Auditory Neurons in the Dorsal Descending Octaval Nucleus in the Goldfish, Carassius auratus". Brain, Behavior and Evolution 88, nr 1 (2016): 68–80. http://dx.doi.org/10.1159/000447943.

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The nucleus medialis is the main first-order target of the mechanosensory lateral line (LL) system. This report definitively demonstrates that mechanosensory LL inputs also terminate in the ipsilateral dorsal portion of the descending octaval nucleus (dDO) in the goldfish. The dDO, which is the main first-order auditory nucleus in bony fishes, includes neurons that receive direct input from the otolithic end organs of the inner ear and project to the auditory midbrain. There are two groups of such auditory projection neurons: medial and lateral. The medial and the lateral groups in turn contain several neuronal populations, each of which includes one or more morphological cell types. In goldfish, the exclusively mechanosensory anterior and posterior LL nerves terminate only on specific cell types of auditory projection neurons in the lateral dDO group. Single neurons in the lateral dDO group may receive input from both anterior and posterior LL nerves. It is possible that some of the lateral dDO neurons that receive LL input also receive input from one or more of the otolithic end organs. These results are consistent with functional studies demonstrating low frequency acoustic sensitivity of the mechanosensory LL in teleosts, and they reveal that the anatomical substrate for sensory integration of otolithic and LL inputs is present at the origin of the central ascending auditory pathway in an otophysine fish.

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Thomas, Lucretia, Renate Reniers, Lénie Torregrossa i Clara Humpston. "Exploring unusual bodily experiences, basic self disturbances and multimodal hallucinations in the non-clinical population: a cross-sectional study". BJPsych Open 7, S1 (czerwiec 2021): S296. http://dx.doi.org/10.1192/bjo.2021.784.

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AimsPsychosis research has largely focused on symptoms which are easier to define. Symptoms which are challenging to detect and articulate, including disturbances in the basic- and bodily-self, may not be volunteered by patients, despite causing significant distress. Increased understanding of such symptoms, which may present in the prodromal phase of psychosis and persist following the remission of positive symptoms, may allow patients who experience these to be better supported.This study aims to explore how disturbances in the basic- and bodily-self relate to multimodal hallucinations. Through sampling a non-clinical population, this study takes the continuum approach to psychosis, where individuals experience sub-clinical psychotic symptoms which do not cause distress or functional impairment.It is hypothesised that individuals with greater hallucination proneness will exhibit greater severity of ambiguous and imprecise mapping of bodily experiences, and will report greater levels of basic and bodily-self disturbance. This project also aims to evaluate Audiograph as a newly developed tool for creating representations of visual hallucinations.MethodThis is a two-stage cross-sectional study. In stage one, participants completed the Multi-Modality Unusual Sensory Experiences Questionnaire to assess hallucination-proneness. In stage two, all participants were invited to complete seven further validated questionnaires which assessed basic- and bodily self-disturbances alongside co-variates including anxiety and depression symptoms, delusion-proneness and loneliness. Participants also completed emBODY, a computer-based task which allows participants to map the bodily sensations they experience during 13 different emotional states. Participants with high-hallucination proneness also completed the Audiograph task. Hierarchical linear regression, conducted using Stata, will be used to model the influence of hallucination proneness on measures of basic- and bodily-self disturbance. MATLAB will be used to generate topographical maps of the data from emBODY; maps will be compared between different emotional states using linear discriminant analysis, and between high and low hallucination proneness groups using Spearman's test.ResultCurrently, 50 of the 104 stage one participants have completed stage two.Since this project comprises a compulsory component of the presenting author's intercalated degree, data collection will cease on the 29th of March in advance of their poster and write-up submission deadlines in May.ConclusionAlthough basic- and bodily-self disturbances have been assessed in previous studies using various techniques, no single study has assessed these alongside multimodal hallucinations to link these concepts together as a whole, especially not in a general population sample. The added value of this project is to precisely address this gap in knowledge.

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Deshpande, Lalitagauri M., Mirela Flonta, Ronald N. Jones i Mariana Castanheira. "Detection of NDM-1-producing Enterobacteriaceae in Romania: report of the SENTRY Antimicrobial Surveillance Program". Journal of Medical Microbiology 63, nr 3 (1.03.2014): 483–84. http://dx.doi.org/10.1099/jmm.0.070334-0.

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Mendes, Rodrigo E., Patricia Garcia, Manuel Guzman, Mark A. Toleman, Ronald N. Jones, Mariana Castanheira i Timothy R. Walsh. "First Isolation of blaVIM-2 in Latin America: Report from the SENTRY Antimicrobial Surveillance Program". Antimicrobial Agents and Chemotherapy 48, nr 4 (kwiecień 2004): 1433–34. http://dx.doi.org/10.1128/aac.48.4.1433-1434.2004.

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Johnson, David M., Matthew G. Stilwell, Thomas R. Fritsche i Ronald N. Jones. "Emergence of multidrug-resistant Streptococcus pneumoniae: report from the SENTRY Antimicrobial Surveillance Program (1999–2003)". Diagnostic Microbiology and Infectious Disease 56, nr 1 (wrzesień 2006): 69–74. http://dx.doi.org/10.1016/j.diagmicrobio.2005.12.008.

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Jones, R., J. Bell, J. Turnidge i D. Mathai. "Multicenter Evaluation of Tigecycline Activity in India: Report from the SENTRY Antimicrobial Surveillance Program (2006)". International Journal of Infectious Diseases 12 (grudzień 2008): e402. http://dx.doi.org/10.1016/j.ijid.2008.05.1060.

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Wittich, Walter, Jonathan Jarry, Fiona Höbler i Katherine S. McGilton. "Agreement on the use of sensory screening techniques by nurses for older adults with cognitive impairment in long-term care: a mixed-methods consensus approach". BMJ Open 9, nr 9 (wrzesień 2019): e027803. http://dx.doi.org/10.1136/bmjopen-2018-027803.

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ObjectiveBased on two scoping reviews and two environmental scans, this study aimed at reaching consensus on the most suitable sensory screening tools for use by nurses working in long-term care homes, for the purpose of developing and validating a toolkit.SettingA mixed-methods consensus study was conducted through two rounds of virtual electronic suitability rankings, followed by one online discussion group to resolve remaining disagreements.ParticipantsA 12-member convenience panel of specialists from three countries with expertise in sensory and cognitive ageing provided the ranking data, of whom four participated in the online discussion.Outcome measuresAs part of a larger mixed-methods project, the consensus was used to rank 22 vision and 20 hearing screening tests for suitability, based on 10 categories from the Quebec User Evaluation of Satisfaction with Assistive Technology questionnaire. Panellists were asked to score each test by category, and their responses were converted to z-scores, pooled and ranked. Outliers in assessment distribution were then returned to the individual team members to adjust scoring towards consensus.ResultsIn order of ranking, the top 4 vision screening tests werehand motion,counting fingers,confrontation visual fieldsand theHOT-V chart, whereas the top 4 hearing screening tests were theHearing Handicap Inventory for the Elderly, theWhisper Test, theMeasure of Severity of Hearing Lossand theHyperacusis Questionnaire, respectively.ConclusionsThe final selection of vision screening tests relied on observable visual behaviours, such as visibility of tasks within the central or peripheral visual field, whereas three of the four hearing tests relied on subjective report. Next, feasibility will be tested by nurses using these tools in a long-term care setting with persons with various levels of cognitive impairment.

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Werkmeister, Raymond F., i Donn E. Hancher. "Paris–Lexington Road Project: Project Report". Transportation Research Record: Journal of the Transportation Research Board 1761, nr 1 (styczeń 2001): 130–36. http://dx.doi.org/10.3141/1761-17.

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Gregori i Cifre, J. M. "Catalonia project report". Early Music 43, nr 2 (2.04.2015): 367–68. http://dx.doi.org/10.1093/em/cav018.

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Nowak, Katarzyna, Halina Muzaj, Halina Nawrocka i Piotr Sobaniec. "Evaluation of the effectiveness of MNRI therapy in children with autism based on the ATEC test – a preliminary report". Rehabilitacja Medyczna 22, nr 3 (23.10.2018): 20–34. http://dx.doi.org/10.5604/01.3001.0012.6899.

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Autism (ASD) is a multiform disorder of unexplored etiology. Therapeutic treatment is therefore symptomatic0 and due to the complexity and variety of symptoms, it must be individualized. Therapists reach for various methods and forms of work with an autistic patient. In this situation, there is also a need to evaluate the therapeutic procedure and the choice of methods that will help assess the effectiveness of therapy. One of the proposed activities is therapeutic modality MNRI (Masgutova Neurosensorimotor Reflex Integration), while the standard ATEC test is used to assess the effectiveness of therapy. The MNRI method deals with the functioning of basic reflexes, the movement system and its impact on the developmental and learning processes. The MNRI method is aimed at restoring normal neurosensoric development and integration of reflex patterns, motor coordination systems and skills enabling movement functioning, behavioural regulation, emotional and cognitive functions. Therapy consists in activating reflex patterns to stimulate the natural resources of the brain, the body, strengthening memory and neurosensotimotive as well as motor integration. The aim of the study was to evaluate the effectiveness of MNRI therapy in children with autism based on the ATEC test. The study involved 60 children diagnosed with autism (F84.0) according to ICD-10 criteria. The average age of patients was 10.7 years. Each participant of the project took an active part in the 11-day rehabilitation process according to the MNRI programme. The standardized ATEC test was used to assess the effectiveness of therapy. Analysis of the results of the ATEC test before and after the 11-day rehabilitation in autistic patients showed positive effects of MNRI therapy among 43.5% of the subjects. These effects included, for part I - in terms of communication, an increase was noted by 9.2%; for part II – socialization0 58.3%; part III - sensory feeling, cognitive awareness, 47.2% and in part IV - physical health, emotions, behaviour, 57.9%. MNRI therapy positively influenced the examined group of autistic patients. Particularly noticeable improvement was expressed in the reduction of self-inflicted harm (65%), reduced hypersensitivity and improvement in sound tolerance (80%), improvement of awareness of one’s own body's (60%); greater calmness, self-control (80%). The therapy is safe, painless, has no negative effects. This article is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. null

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Jolliff, Jeffrey C., Jackie Ho, Jeremiah Joson, Arash Heidari i Royce Johnson. "Treatment of Polymicrobial Osteomyelitis with Ceftolozane-Tazobactam: Case Report and Sensitivity Testing of Isolates". Case Reports in Infectious Diseases 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/1628932.

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Stenotrophomonas maltophiliais an inherently multidrug resistant (MDR) opportunistic pathogen with many mechanisms of resistance. SENTRY studies reveal decreasing sensitivities ofS. maltophiliato trimethoprim-sulfamethoxazole and fluoroquinolones. Ceftolozane-tazobactam (Zerbaxa, Merck & Co., Inc.) a novel intravenous combination agent of a third-generation cephalosporin andβ-lactamase inhibitor was demonstrated to havein vitroactivity against many Gram-positive, Gram-negative, and MDR organisms. Data for ceftolozane-tazobactam’s use outside of Food and Drug Administration (FDA) approved indications has been limited thus far to two case reports which demonstrated its efficacy in pan-resistantPseudomonas aeruginosapneumonia. Herein, we describe the first published case of treatment of MDRS. maltophiliain polymicrobial osteomyelitis with long-term (>14 days) ceftolozane-tazobactam and metronidazole. Ceftolozane-tazobactam may offer a possible alternative for clinicians faced with limited options in the treatment of resistant pathogens including MDRS. maltophilia.

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Davis, Lissa, i Cordelia Running. "The Gummy Flavor Game Protocol: Gamifying Vegetable Flavor Exposure to Increase Liking". Current Developments in Nutrition 6, Supplement_1 (czerwiec 2022): 1137. http://dx.doi.org/10.1093/cdn/nzac072.009.

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Abstract Objectives Vegetable consumption in the U.S. population is well below recommendations, which relates to poorer health outcomes. Both adults and children report that unpleasant flavor is a common reason for avoiding vegetables. This flavor problem, however, should be manageable, as myriad studies indicate that repeated exposure to flavors, even unpleasant vegetable flavors, improves acceptability. Yet, increasing exposure to vegetables is difficult, as vegetables are often less convenient to consume and less available than other foods. We propose to address this barrier to repeated exposure through use of a game, challenging players to identify flavors in vegetable flavored gummy candies. Methods This pilot project will test the efficacy of our game in college students. Baseline testing will collect sensory ratings (bitterness, sweetness, and disliking/liking) of pureed and chopped target (exposed in game) and non-target (not exposed in game) vegetables. Baseline testing will also ask about habitual intake and attitudes toward fruits and vegetables. Participants will then complete a 2-week game phase, where they will play the game once per day, with sensory evaluation of the pureed/chopped vegetables repeated at the beginning, middle, and end of the game phase. Participants will be randomly assigned to a control group (non-vegetable flavors) or a vegetable group (vegetable flavors). Results At the end of the experiment, we will have data on how liking and sensation of vegetables change after 2 weeks of playing the game, and whether baseline or changes in sensory ratings are influenced by dietary intake of and attitudes towards fruits and vegetables. We expect the vegetable group to show improved sensory ratings for the target vegetables, with lesser/no changes in ratings for the non-target vegetables. Additionally, we expect to see no or minimal changes in any sensory ratings for the control group. Conclusions This work will test an innovative approach to improve vegetable acceptance. As a result, we will have initial data on whether this approach might be useful for helping people improve their diets. Future work will build on this, using the game in tandem with approaches to improve access to vegetables and preparation skills. Funding Sources Purdue University College of Health and Human Sciences

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Fritsche, Thomas R., Helio S. Sader, Mark A. Toleman, Timothy R. Walsh i Ronald N. Jones. "Emerging Metallo‐β‐Lactamase–Mediated Resistances: A Summary Report from the Worldwide SENTRY Antimicrobial Surveillance Program". Clinical Infectious Diseases 41, s4 (15.08.2005): S276—S278. http://dx.doi.org/10.1086/430790.

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Deshpande, Lalitagauri M., Ronald N. Jones, Thomas R. Fritsche i Helio S. Sader. "Occurrence and Characterization of Carbapenemase-Producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program (2000–2004)". Microbial Drug Resistance 12, nr 4 (grudzień 2006): 223–30. http://dx.doi.org/10.1089/mdr.2006.12.223.

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Deshpande, Lalitagauri M., Thomas R. Fritsche i Ronald N. Jones. "Molecular epidemiology of selected multidrug-resistant bacteria: A global report from the SENTRY Antimicrobial Surveillance Program". Diagnostic Microbiology and Infectious Disease 49, nr 4 (sierpień 2004): 231–36. http://dx.doi.org/10.1016/j.diagmicrobio.2004.03.014.

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Messer, S. A., R. N. Jones i T. R. Fritsche. "International Surveillance of Candida spp. and Aspergillus spp.: Report from the SENTRY Antimicrobial Surveillance Program (2003)". Journal of Clinical Microbiology 44, nr 5 (1.05.2006): 1782–87. http://dx.doi.org/10.1128/jcm.44.5.1782-1787.2006.

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Farrell, D. J., H. Sader, S. D. Putnam i R. N. jones. "Multicenter evaluation of tigecycline activity in Latin America: Report from the SENTRY antimicrobial surveillance program (2009)". International Journal of Infectious Diseases 14 (marzec 2010): e344-e345. http://dx.doi.org/10.1016/j.ijid.2010.02.386.

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Valicente, Vinicius (Vinnie), Nana Gletsu-Miller i Cordelia Running. "Study Protocol: Sensory Effects of Replacing Sugar Sweetened Sodas With Unsweetened, Flavored Sparkling Water". Current Developments in Nutrition 6, Supplement_1 (czerwiec 2022): 1160. http://dx.doi.org/10.1093/cdn/nzac072.032.

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Abstract Objectives Excess sugar consumption contributes to numerous chronic diseases. Prior work has typically emphasized replacing sugar-sweetened beverages, a key source of excess dietary sugar, with low-calorie sweetened beverages. Our protocol aims to instead replace sugar sodas with unsweetened, flavored sparkling water products, which are available in the same containers and at comparable prices to sugary sodas. Methods Participants who consume at least 2 sugar-sweetened sodas per day are being recruited for this project. Flavored, unsweetened sparkling waters will be provided to participants for 2 weeks, with sensory evaluations at baseline, 1 week, and 2 weeks. At the end of the 2-week intervention, we will provide participants with information on the costs and how to find the flavored, unsweetened sparkling water products. Two weeks post intervention, participants will be asked whether they continued to consume the sparkling waters or if they reverted back to sugar-sweetened soda consumption. We will use linear mixed models with subject as a repeated measure to determine the effect of replacement of sugar-sweetened sodas beverages with sparkling waters on: liking of sweetness in soda-like beverages, “just about right” concentration of sugar/intensity of sweetness in soda-like beverages, and post-intervention beverage selection. Results As this is a protocol abstract, results have yet to be obtained. However, we hypothesize that participants who comply with substituting sparkling waters for sweetened sodas will exhibit sensory shifts to prefer lower concentrations of sugar and liking for lower sweetness intensity in beverages. We expect these participants will also report continuing to consume the sparkling water products at 2 weeks post intervention. Conclusions Data from this study will inform future work on whether commercially available water products could shift sensory preferences for sweetness, which could aid in interventions to curb added sugar intake. Funding Sources This study is supported by a Pilot and Feasibility Award within the Indiana CTSI/CDMD, an initiative funded by the NIH/NIDDK.

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