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Callahan, Bryan Thomas. "Syphilis and civilization a social and cultural history of sexually transmitted disease in colonial Zambia and Zimbabwe, 1890-1960 /". [S.l. : s.n.], 2002. http://books.google.com/books?id=JQnbAAAAMAAJ.
Pełny tekst źródłaParsonson, Ian M. "Syphilis and AIDS historical and social comparisons /". Connect to this title online, 1992. http://tux.lib.deakin.edu.au/adt-VDU/public/adt-VDU20031118.111824/.
Pełny tekst źródłaJulienne, Isabelle. "La syphilis congénitale précoce". Caen, 1990. http://www.theses.fr/1990CAEN3049.
Pełny tekst źródłaMeyer, Michael Peter. "Congenital syphilis and rheumatoid factor". Doctoral thesis, University of Cape Town, 1990. http://hdl.handle.net/11427/26298.
Pełny tekst źródłaSabisch, Katja. "Das Weib als Versuchsperson medizinische Menschenexperimente im 19. Jahrhundert am Beispiel der Syphilisforschung". Bielefeld Transcript, 2007. http://deposit.d-nb.de/cgi-bin/dokserv?id=3015478&prov=M&dok_var=1&dok_ext=htm.
Pełny tekst źródłaMercier, Cassandre Stalder Jean-François. "Epidémie de syphilis dans la région nantaise à propos de 39 cas /". [S.l.] : [s.n.], 2004. http://theses.univ-nantes.fr/thesemed/PHmercier.pdf.
Pełny tekst źródłaFournier, Alfred. "De la contagion syphilitique thèse pour le doctorat en médecine présentée et soutenue le 14 février 1860 /". Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1860x024.
Pełny tekst źródłaBOURRIERES, CATHERINE. "Histoire de la syphilis maligne precoce". Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20090.
Pełny tekst źródłaDobson, Simon R. M. "Immune responses in congenital syphilis". Thesis, University of Newcastle Upon Tyne, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352919.
Pełny tekst źródłaBrou-Paris, Akoua Dellion Sophie. "Recrudescence de la syphilis cas du centre hospitalier intercommunal de Villeneuve-Saint-Georges dans le Val de Marne /". Créteil : Université de Paris-Val-de-Marne, 2006. http://doxa.scd.univ-paris12.fr:80/theses/th0236687.pdf.
Pełny tekst źródłaDasaah, Edward Tieru. "Evaluation of access to antenatal syphilis screening and the performance of syphilis sentinel surveillance in Ghana". Thesis, London School of Hygiene and Tropical Medicine (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558358.
Pełny tekst źródłaGROSREY, ROUSSEAU CATHERINE. "La syphilis acquise precoce de l'enfant en milieu non endemique". Lyon 1, 1989. http://www.theses.fr/1989LYO1M457.
Pełny tekst źródłaCLARIOND, YVES. "Les hepatites au cours de la syphilis secondaire : a propos de trois observations". Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20137.
Pełny tekst źródłaLinöcker, Melanie. "Der Unzucht und Lastern derbey entspringende Krankheit Syphilis und deren Bekämpfung in der Frühen Neuzeit am Beispiel des Wiener Bürgerspitals St. Marx". Saarbrücken VDM Verlag Dr. Müller, 2006. http://d-nb.info/988567938/04.
Pełny tekst źródłaBircks, Anna [Verfasser]. "Syphilis - eine szientometrische Analyse / Anna Bircks". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023784750/34.
Pełny tekst źródłaSamson, Gregory Raymond. "An immune study of newborn infants with congenital syphilis". Thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/26182.
Pełny tekst źródłaMESSA, JEAN-LOUIS. "Syphilis congenitale precoce : etude a propos de 65 cas". Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20136.
Pełny tekst źródłaLin, Luyang. "The transmission and control of syphilis in Guangzhou". Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41711191.
Pełny tekst źródłaFroidefond, Claudine. "Syphilis congénitale : à propos d'une observation à IGM initialement négatives chez un enfant adopté, avec syndrome néphrotique, anémie pseudoleucémique, neuro-syphilis, atteinte hépatique et osseuse : mise au point sur les données de la littérature". Bordeaux 2, 1991. http://www.theses.fr/1991BOR2M106.
Pełny tekst źródłaTissot-Guerraz, Françoise. "Contribution a l'étude de la biologie des tréponématoses". Lyon 1, 1991. http://www.theses.fr/1991LYO1H096.
Pełny tekst źródłaParsonson, Ian Malcolm, i kimg@deakin edu au. "SYPHILIS AND AIDS: HISTORICAL AND SOCIAL COMPARISONS". Deakin University. School of Humanities, 1992. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20031118.111824.
Pełny tekst źródłaMOULY, PAU ISABELLE. "Un cas d'atteinte syphilitique non anevrysmale de l'aorte sous renale". Toulouse 3, 1991. http://www.theses.fr/1991TOU31104.
Pełny tekst źródłaСулим, Анатолій Григорович, Анатолий Григорьевич Сулим i Anatolii Hruhorovych Sulym. "Випадок помилкової діагностики вторинного свіжого сифілісу". Thesis, Видавництво СумДУ, 1997. http://essuir.sumdu.edu.ua/handle/123456789/24770.
Pełny tekst źródłaКутова, В. В., О. М. Білоконь i В. М. Волкославська. "Специфічні скринінгові дослідження на сифіліс". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/64425.
Pełny tekst źródłaComparative evaluation of the effectiveness of specific diagnostic tests for treponemа population screening diagnosis of syphilis.
MAY, REGINE. "De la syphilis au sida, de la paralysie cerebrale a la demence du sida". Lille 2, 1994. http://www.theses.fr/1994LIL2M085.
Pełny tekst źródła林路洋 i Luyang Lin. "The transmission and control of syphilis in Guangzhou". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41711191.
Pełny tekst źródłaPlumb, Ellen Joyce. "Syphilis and AIDS in Uganda: an historical perspective". Thesis, Boston University, 2002. https://hdl.handle.net/2144/27745.
Pełny tekst źródłaPLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
2031-01-02
Randall, Lesa Beth. "Representations of syphilis in sixteenth-century French literature". Diss., The University of Arizona, 1999. http://hdl.handle.net/10150/284029.
Pełny tekst źródłaEsselaar, Annette. "Congenital syphilis : a study at Provincial Hospital Uitenhage". Master's thesis, University of Cape Town, 1998. http://hdl.handle.net/11427/27002.
Pełny tekst źródłaGUERIN, BOUCKAERT MARIE-FRANCOISE, i Philippe Guérin. "Maladies infectieuses et toxicomanie : vih, vhb, vhd, syphilis". Lille 2, 1989. http://www.theses.fr/1989LIL2M421.
Pełny tekst źródłaLaFond, Rebecca E. "Variability of tprK and the immune response to tprK variants during Treponema pallidum infection /". Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/9298.
Pełny tekst źródłaRubi, Gérald. "Neurosyphilis révélatrice d'une co-infection à VIH : à propos d'un cas". Montpellier 1, 1997. http://www.theses.fr/1997MON11151.
Pełny tekst źródłaMagalhães, Daniela Mendes dos Santos [UNESP]. "Fatores sócio-demográficos e antecedentes obstétricos relacionados à sífilis na gestação em uma amostra de gestantes do Distrito Federal". Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/99203.
Pełny tekst źródłaFundação de Ensino e Pesquisa em Ciências da Saúde (FEPECS)
A sífilis na gestação é um grave problema de saúde pública, responsável por altos índices de morbimortalidade intrauterina. Estima-se que leve, em pelo menos 50% das gestações acometidas, a desfechos perinatais adversos. Esses dados remetem à falta de controle das doenças sexualmente transmissíveis (DST) e à deficiência na assistência pré-natal. O objetivo deste estudo transversal foi conhecer o perfil sócio-demográfico e os antecedentes obstétricos das gestantes com VDRL reagentes no DF no ano de 2010. Verificou-se o percentual de gestantes que tiveram acesso ao pré-natal e foram inadequadamente tratadas de acordo com as recomendações do MS. Foram entrevistadas 67 gestantes/ puérparas notificadas no SINAN, em cinco maternidades públicas do DF e consultadas as informações do prontuário e cartão da gestante quando disponível. Foram avaliados dados sóciodemográficos, obstétricos, informações relacionadas ao diagnóstico e tratamento da gestante/puérpara e parceiro. Apenas 41,8% gestantes foram adequadamente tratadas e o principal motivo para a inadequação do tratamento foi a falta (83,6%) ou inadequação do tratamento do parceiro (88,1%). Foi constatada a necessidade de novo tratamento da gestante na maternidade por falta de documentação do tratamento realizado no pré-natal. Os dados demonstram que a qualidade do pré-natal recebido pela gestante não é suficiente para garantir o controle da sífilis congênita e o atingimento da meta de controle da doença
Syphilis during pregnancy is a serious public health problem responsible for high rates of intrauterine mortality. It is estimated that in at least 50% of pregnancies affected, adverse perinatal outcomes happen. These findings reflect the lack of control of sexually transmitted diseases (STDs) and disability in prenatal care. The goal of this survey was to understand the epidemiological profile of women with VDRL reagents in the Federal District in 2010. The study verified the percentage of pregnant women who had access to prenatal care and were inadequately treated in accordance with the recommendations of the Ministry of Health. We interviewed 67 pregnant and postpartum women who reported to the SINAN, users of five public hospitals of the DF and consulted information from medical records and from prenatal care charts, when available. Data were collected on sociodemographic, obstetric, information related to diagnosis and treatment of pregnant and puerperal women and their partners. Only 28 (41.8%) patients were adequately treated and the main reason for inadequacy was the lack of treatment (83.6%) or inadequate treatment of the partner (88.1%). The study demonstrated the need for new treatment of the mother at the hospital for lack of documentation of the treatment in prenatal care. Our data demonstrates that the quality of prenatal care received by pregnant women is not sufficient to ensure control of congenital syphilis and reaching the goal of controlling the disease
Ussher, Greg. "'The medical gaze and the watchful eye' : the treatment, prevention and epidemiology of venereal diseases in New South Wales c.1901 - 1925". University of Sydney, 2007. http://hdl.handle.net/2123/3565.
Pełny tekst źródłaFrom Federation in 1901 through the first three decades of the twentieth century there was a perceptible shift in modes of rule in New South Wales (NSW) related to the management of venereal diseases. At the beginning of the twentieth century a medicopenal approach was central. By 1925, persuasion and ‘responsibilisation’ were becoming important modes, and young people rather than ‘case-hardened prostitutes' were assessed as being a ‘venereal’ risk. Framing this period were three important legislative developments which informed, and were informed by, these shifts: the NSW Prisoners Detention Act 1909, the NSW Select Committee into the Prevalence of Venereal Diseases 1915 and the NSW Venereal Diseases Act 1918. At its core this thesis is concerned with examining shifting modes of rule. This thesis closely examines each. I suggest that these modes of rule can be viewed through the lens of biopolitics, and following Foucault, deploy the ‘medical gaze’ and the ‘watchful eye’ as constructs to examine the relationship between the government of self, government of others and government of the state. I use the medical gaze to describe not only the individual venereal patient attending a hospital and the body of the patient diagnosed with syphilis and/or gonorrhoea, but most importantly to describe the power relationship between the medical practitioner, the teaching hospital and the patient. I use the watchful eye in a more overarching way to suggest the suite of techniques and apparatus deployed by government to monitor and regulate the venereal body politic, both the populations perceived to be posing a venereal risk, and populations at risk of venereal infection. In relation to the venereal body and the venereal body politic, I analyse three fundamental aspects of the management of venereal diseases: treatment, prevention and epidemiology. Treatment: Over this period, treatment moved from lock institutions to outpatient clinics. Embodied in this change was a widespread institutional ambivalence towards treating venereal patients. I contend that treatment of venereal diseases was painful, prolonged and punitive precisely because of the moral sickness perceived to be at the iv heart of venereal infection. I track this ambivalence to a systemic fear of institutional ‘venerealisation’, which decreased perceptibly across the period. Closely analysing surviving patient records, I argue that in their conduct, venereal patients were often compliant, conscientious and responsible. Prevention: I argue that preventative approaches to venereal diseases became increasingly complex, and operated in three domains – preventative medicine (diagnosis, treatment and vaccination); public health prevention (notification, isolation and disinfection); and prevention education (social purity campaigns and sex hygiene). An emerging plethora of community-based organisations and campaigns began to shift the sites and practices of power. Epidemiology: I suggest that there was a shift from danger to risk in the conceptualisation of venereal diseases. This shift necessitated a focus on factors affecting populations, as opposed to factors affecting individuals. This in turn led to the deployment of various techniques to monitor the conduct of venereal populations. The NSW Venereal Diseases Act 1918 created two important new venereal categories: the ‘notified person’ and the ‘defaulter,’ both of which came to permeate renditions of venereal patients throughout the 20th century.
Chan, Cucciniello Christine. "Les comportements psychosociaux face a deux maladies : la syphilis avant le xxeme siecle et le sida". Clermont-Ferrand 1, 1991. http://www.theses.fr/1991CLF13012.
Pełny tekst źródłaLAGRANGE, JEAN-PIERRE. "Relation entre la syphilis et le risque d'hépatite B en Loire-Atlantique". Nantes, 1988. http://www.theses.fr/1988NANT159M.
Pełny tekst źródłaSWIADER, LAURE. "Pheochromocytome malin et aortite vegetante : discussion nosologique". Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20806.
Pełny tekst źródłaPEREZ, LAUREAU CHRISTINE. "Neurosyphilis et infection par le virus de l'immunodeficience humaine". Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20112.
Pełny tekst źródłaDallé, Jessica. "Sífilis em gestantes e o tratamento do parceiro sexual". reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/159600.
Pełny tekst źródłaIntroduction: Syphilis in pregnant women is a public health problem, with increasing cases each year. Treatment of the sexual partner of the pregnant women with syphilis is very important because the lack of treatment may invalidate all control measures imposed during prenatal care. Objective: to describe the occurrence of treatment of the sexual partner and evaluate maternal factors that favor the realization of the treatment of the sexual partner of pregnant women with gestational syphilis treated in Hospital Fêmina. Method: This is a cross-sectional descriptive study, in which were described the cases of patients diagnosed with gestational syphilis in the Obstetrics Department of Hospital Fêmina, and their partners, from January 1st 2007 to December 31st 2014. Data collection was done through the data sent by the Department of Infection Control to Department of Health Surveillance of Porto Alegre in syphilis, along with the records of patients. Ethical principles will be were respected. The project had approval of the ethics committee of Grupo Hospitalar Conceição under protocol number 47914815.2.0000.5530. Results: 771 cases of syphilis in pregnant women were identified. No information on the treatment of the sexual partners was available in 570 of these cases. Among the 201 cases presenting information about the partners treatment, 25 (12.44%) of them were adequately treated. In the univariate analysis comparing women whose partners were treated for syphilis with those untreated demonstrates the associated characteristics as: a) more than eight years of study (p =0.022); b) adequate prenatal care (p= 0.010) and diagnosis of syphilis in prenatal care (p= 0.003). Conclusion: The years of study, the early diagnosis of syphilis and an adequate prenatal care appear to be determining factors for appropriate partner treatment and prevention of the vertical transmission of the disease.
Kitayama, Ken, Eddy R. Segura, Jordan E. Lake, Amaya G. Perez-Brumer, Catherine E. Oldenburg, Bethany A. Myers, Paria Pourjavaheri, Chinomnso N. Okorie, Robinson L. Cabello i Jesse L. Clark. "Syphilis in the Americas: a protocol for a systematic review of syphilis prevalence and incidence in four high-risk groups, 1980–2016". Biomed Central Ltd, 2017. http://hdl.handle.net/10757/622278.
Pełny tekst źródłaArmour, Patricia. "Usefulness of the Captia Syphilis IgG EIA test method and reverse algorithm for detection of syphilis infection in a public health setting". VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5341.
Pełny tekst źródłaSilva, Vivian Sauer Torres da [UNESP]. "Os (Des) caminhos da sífilis congênita em Botucatu/São Paulo". Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/138179.
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A sífilis congênita é um evento sentinela e um dos mais graves desfechos adversos que podem ser prevenidos durante a gestação. Sua eliminação configura-se como desafio diretamente ligado ao controle da sífilis na gestação, tanto pela atenção à saúde da gestante, quanto à de seus parceiros. A alta prevalência da transmissão vertical vem apontando perdas de oportunidades durante todas as fases da doença na gestação, justificando o presente estudo que teve por objetivo analisar o itinerário terapêutico percorrido por mães que tiveram filhos notificados como caso de sífilis congênita no Sistema de Informação de Agravos de Notificação e propor fluxo de cuidados a gestantes diagnosticadas com sífilis no âmbito da Atenção Primária à Saúde. Trata-se de pesquisa exploratória de cunho qualitativo embasada no referencial teórico do Itinerário Terapêutico. Fizeram parte do estudo 17 mães que tiveram filhos nascidos no período de janeiro de 2013 a dezembro de 2014. Os dados foram obtidos por consulta as ficha de notificação de sífilis em gestante e de sífilis congênita, ficha de acompanhamento domiciliar de sífilis congênita do Programa Municipal de Doenças Sexualmente Transmissíveis/Aids, prontuários e por meio de entrevista semiestruturada com as mães. A análise dos dados foi realizada segundo a técnica de Análise de Conteúdo de Bardin, na vertente Temática. Predominaram as mães que tinham alto nível de escolaridade, baixa renda, multiplicidade de parceiros sexuais na vida, multiparidade e antecedente de sífilis. Verificou-se que houve o uso de drogas ilícitas durante o período gestacional por duas mães investigadas. A maioria das mães realizou o pré-natal em unidades básicas de saúde do município, com seis ou mais consultas, entretanto, cinco mães iniciaram o pré-natal no terceiro trimestre de gestação, sete tiveram o diagnóstico de sífilis no terceiro trimestre de gestação e uma no parto, seis mães não finalizaram o tratamento em até 30 dias antes do parto, e ocorreram dois óbitos fetais. A maioria dos bebês apresentou sinais clínicos e/ou alterações laboratoriais sugestivas de sífilis congênita. A maior parte dos parceiros não foi tratada. A análise das entrevistas permitiu a exploração de três temas e seus respectivos núcleos de sentido: Tema 1 - Foi muito difícil ter sífilis na gestação; Tema 2 - Foi bem doloroso ver meu bebê ficar internado e Tema 3 - Apesar de tudo, ainda sei pouco sobre sífilis. Pela análise do itinerário terapêutico das mães, pôde-se depreender que este foi marcado por preocupação, medo, decepção, dor, violência institucional e cuidado desumanizado que implicaram sofrimento, superado com apoio de familiares e profissionais de saúde. Com base nos achados deste estudo foi elaborada uma proposta de fluxo de cuidados dirigido as gestantes com sífilis focado no processo de trabalho das equipes da rede de atenção primária à saúde, desde o diagnóstico até o nascimento. Por fim, considera-se que este estudo vem contribuir para o planejamento de ações mais abrangentes voltadas ao cuidado integral de gestantes com diagnóstico de sífilis e à prevenção da sífilis congênita, uma vez que revela dificuldades enfrentadas por mulheres que tiveram filhos notificados como caso de sífilis congênita, além de aspectos da vulnerabilidade individual, social e programática que devem ser abordados na atenção integral à saúde deste grupo populacional.
Congenital syphilis is a sentinel event and one of the most severe adverse outcomes that can be prevented during pregnancy. Its elimination represents a challenge directly linked to syphilis control during pregnancy, because of the care for the pregnant woman’s and her partners’ health. The high prevalence of vertical transmission has appointed the loss of opportunities during all phases of the disease during pregnancy, justifying this study, which was intended to analyze the therapeutic itinerary of mothers whose infants were notified as cases of congenital syphilis in the Reportable Disease Information System and to propose a care flow for pregnant women diagnosed with syphilis in Primary Health Care. An exploratory and qualitative research was undertaken based on the theoretical framework of the Therapeutic Itinerary. The study participants were 17 mothers who had children born between January 2013 and December 2014. The data were collected by consulting the notification forms for syphilis in pregnant women and congenital syphilis, as well as the domestic monitoring form of congenital syphilis of the Municipal Program for Sexually Transmitted Diseases/Aids, patient histories and semistructured interviews with the mothers. The data were analyzed using Bardin’s Thematic Content Analysis. Mothers were predominant with a high education level, low income, multiple sexual partners in life, multiple births and a history of syphilis. Two of the mothers had used illegal drugs during pregnancy. Most of the mothers received antenatal care at primary health care services in the cities, with six or more consultations, but five mothers started antenatal care in the third pregnancy term, seven were diagnosed with syphilis in the third term and one when giving birth, six mothers did not get treatment in the first 30 days after birth and two fetal deaths occurred. Most of the infants presented clinical signs and/or laboratory changes suggesting congenital syphilis. Most of the partners were not treated. The analysis of the interviews permitted exploring three themes and their respective central meanings: Theme 1 – It was very difficult to have syphilis during pregnancy; Theme 2 – It was very difficult to see my baby in hospital and Theme 3 – Despite everything, I still know little about syphilis. Based on the analysis of the mothers’ therapeutic itinerary, it could be inferred that it was marked by concern, fear, deceit, pain, institutional violence and dehumanized care, which implied suffering, overcome with the support of family members and health professionals. Based on these study findings, a care flow proposal was elaborated focused on the pregnant women with syphilis. Finally, this study contributes to the planning of more comprehensive actions focused on integral care delivery to pregnant women diagnosed with syphilis and on the prevention of congenital syphilis, as it reveals difficulties faced by women with children notified as cases of congenital syphilis, besides aspects of individual, social and program vulnerability, which should be addressed in integral health care for this population group.
Sampson, Lynne Arlene Miller William C. "Screening for syphilis and HIV in North Carolina jails". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1980.
Pełny tekst źródłaTitle from electronic title page (viewed Dec. 11, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Epidemiology." Discipline: Epidemiology; Department/School: Public Health.
Watson-Jones, Deborah Lindsay. "Impact of syphilis on outcome of pregnancy and evaluation of syphilis screening strategies for the reduction of adverse pregnancy outcomes in Mwanza, Tanzania". Thesis, London School of Hygiene and Tropical Medicine (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246851.
Pełny tekst źródłaAlmeida, Anelisa Soares de. "Gestantes notificadas com sífilis e ocorrência de sífilis congênita estudo de coorte retrospectiva /". Botucatu, 2018. http://hdl.handle.net/11449/157351.
Pełny tekst źródłaResumo: A sífilis é doença causada pelo Treponema pallidium e transmitida por via sexual, hematogênica ou vertical. Sua forma congênita ocorre quando a gestante com sífilis não tratada ou tratada inadequadamente transmite a doença para o recém-nascido. Tem-se por objetivo investigar a ocorrência e a influência de fatores maternos e relativos ao pré-natal sobre a sífilis congênita. Trata-se de estudo de coorte retrospectiva, formada por 158 casos de sífilis em gestantes notificados no período de 2013 a 2015, com seguimento realizado pelo Programa de DST/Aids de município de médio porte do interior paulista. A análise estatística foi realizada descritivamente e por regressão logística múltipla, sendo considerado p crítico <0,05. A maior parte das gestantes notificadas em decorrência da sífilis era branca, tinha nove ou mais anos de escolaridade e trabalho não remunerado; quase a totalidade havia feito pré-natal (96,8%). Do total de gestantes incluídas na coorte, 74 (46,8%) tiveram recém-nascido classificado com sífilis. A análise univariada evidenciou que a chance de sífilis congênita foi menor entre as mulheres com maior escolaridade, maior número de consultas e realização de acompanhamento pré-natal em Unidade de Saúde da Família e foi maior quanto maior a idade gestacional no início do tratamento e quanto maior a titulação do exame não treponêmico materno (p<0,20). Essas variáveis foram incluídas em modelo de regressão logística final, que evidenciou ser o número de consultas pré-na... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Syphilis is a recent disease caused by Treponema pallidium and transmitted sexually, hematogenously or vertically. Its congenital form occurs when a pregnant woman with syphilis is not treated or treated improperly to make the newborn. It aims to investigate the occurrence and influence of maternal and prenatal factors on congenital syphilis. This is a retrospective study, formatted for 158 cases of syphilis in pregnant women reported in the period from 2013 to 2015, with follow-up performed by the STD / AIDS Program of a medium-sized municipality in the state of São Paulo. Statistical analysis was performed descriptively and by regression, with the announcement of p <0.05. The majority of the pregnant women noticed the result of syphilis was white, superior or superior to schooling and unpaid work; already had a prenatal care (96.8%). Of the total number of pregnant women included in the cohort, 74 (46.8%) had newborns classified as having syphilis. The univariate analysis showed that the chance of congenital syphilis was lower among women with higher schooling, higher number of visits and prenatal follow-up in the Family Health Unit, and the higher the greater the gestational age at the beginning of treatment and the maternal non-treponemal test (p <0.20). These variables were included in a final logistic regression model, which showed that the number of prenatal consultations was the only factor independently associated with the occurrence of congenital syphilis, with a lo... (Complete abstract click electronic access below)
Mestre
Sandes, Valcieny de Souza. "Análise de nova metodologia na triagem sorológica para sífilis em doadores de sangue". Niterói, 2017. https://app.uff.br/riuff/handle/1/3050.
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Introdução: Após 110 anos da descoberta do primeiro teste sorológico para sífilis, a doença continua sendo um problema de saúde pública. Os testes sorológicos desempenham papel fundamental no diagnóstico da doença. A evolução de vários testes e a introdução de novas metodologias de testes treponêmicos frequentemente geram dúvidas na hora da interpretação dos resultados. Nos bancos de sangue, resultados discordantes e falsos positivos geram desconforto na relação com o doador. O presente trabalho se propõe a fazer uma análise da introdução recente do teste treponêmico por quimioluminescência na triagem sorológica para sífilis em doadores de sangue do Serviço de Hemoterapia do Instituto Nacional de Câncer José Alencar Gomes da Silva no Rio de Janeiro. Metodologia: Trata-se de um estudo retrospectivo e exploratório a partir dos resultados de triagem e confirmatórios de testes para Sífilis no Laboratório de Sorologia do Serviço de Hemoterapia do INCA no período de Janeiro de 2010 a Junho de 2014. Na primeira parte do estudo, foi realizada uma revisão bibliográfica sobre sensibilidade e especificidade dos principais testes sorológicos para sífilis. A segunda parte foi dividida em três fases: i) uma análise comparativa do perfil de resultados na triagem sorológica utilizando os testes VDRL (Veneral Disease Research Laboratory) entre 2010 e 2011 e ChLIA (Chemiluminescent Immunoassay) entre 2012 e 2013); ii) análise das propriedades e concordância de dois testes ChLIA (Architect® Syphilis TP e Liaison® Treponema Scren) com o FTA-ABS (Fluorescent Treponemal Antibody-Absortion) como comparador; iii) e análise de possíveis associações das variáveis idade, gênero, estado civil, nível de escolaridade, utilização de medicamentos e concomitância de reatividade para outros agentes infecciosos com resultados positivos e/ou falsos positivos. Resultados: A revisão bibliográfica incluiu 49 artigos. A variação da sensibilidade e da especificidade encontrada foi: 62,2 – 83,7 e 83,9 – 100 para o VDRL; e 95,8 – 100 e 78,4 – 100 para o ChLIA, respectivamente. No período em que foi utilizado o VDRL, a taxa de reatividade para sífilis foi de 1,01% (N = 28.158). Dos inicialmente reativos, foi possível confirmar o resultado após coleta da segunda amostra de 65,96% (188) dos doadores. Já no período em que foi utilizado o ChLIA, foram triados 25.577 doadores e a taxa de reatividade para sífilis aumentou para 2,66%. Retornaram para coleta de segunda amostra 52,48% (360) doadores. Foi encontrado perfil de resultados semelhantes com taxas de falsos positivos de 40,5% para o VDRL e 37,4% para o ChLIA (p = 0,5266). Entre os testes ChLIA, o Liaison® Treponema Scren apresentou melhores resultados de concordância com o FTA-ABS e especificidade (81% e 87% respectivamente) do que o Architect® Syphilis TP (71% e 79%). Foi encontrada associação entre idade mais avançada e níveis de escolaridade mais baixos com os resultados positivos para sífilis. Conclusão: A nova metodologia introduzida na triagem sorológica apresentou desempenho inferior ao esperado quanto à especificidade. Este resultado sugere a importância de se investir em estudos para avaliar custo-efetividade de novas estratégias para redução das perdas de doadores em casos de falsos positivos
Introduction: Since the discovery of the first syphilis serological test 110 years ago, the disease remains a public health problem. Serologic tests play an important role in diagnosis of the disease. Various tests have become available and the introduction of new treponemal tests often raises questions at the time of interpretation. In blood banks, discordant and false positives results causing discomfort in the relationship with donor. This study analyzed the recent introduction of a treponemal chemiluminescent assay in syphilis screening in blood donors of the Hemotherapy Service/INCA/RJ. Methodology: A retrospective exploratory study was performed based on results of screening and confirmatory tests for syphilis in the Hemotherapy Service of INCA from January 2010 to June 2014. In the first part of the study, a literature review on sensitivity and specificity of the main serologic tests for syphilis was performed. The second part was divided into three phases: i) a comparative analysis of positives, negatives and false positives results in screening using the VDRL test (Venereal Disease Research Laboratory) between 2010 and 2011 and ChLIA (Chemiluminescent Immunoassay) between 2012 and 2013; ii) a concordance analysis of two ChLIA tests (Architect® Syphilis TP and Liaison® Treponema Scren) with the FTA-ABS (Fluorescent Treponemal Antibody-Absorption) as a comparator; iii) and an analysis of possible association of age, gender, marital status, educational level, use of medicines and reactivity for other infectious agents with positive and/or false positive test results. Results: The literature review includes 49 articles. The variation of sensitivity and specificity found was: 62.2 to 83.7 and from 83.9 to 100 for VDRL; and 95.8 - 78.4 and 100 - 100 for ChLIA respectively. In VDRL test period the reactivity rate for syphilis was 1.01% (N = 28 158). It was possible to confirm the result after collecting the second sample in 65.96% (188) of donors with initially reactive test results. In ChLIA period, 25,577 donors were screened and the reactivity rate for syphilis increased to 2.66%. Second samples were collected from 52.48% (360) donors. A similar profile was found with false positive rate of 40.5% for VDRL and 37.4% for ChLIA (p = 0.5266). In the ChLIA tests assessed, Liaison® Treponema Screen showed a better agreement with FTA-ABS and specificity (81% and 87% respectively) than the Architect® Syphilis TP (71% and 79%). An association between elderly and lower education status with positive results for syphilis was found. Conclusion: The new methodology introduced in serological screening showed a lower performance than expected in specificity. This result suggests the importance of investing in studies to evaluate cost-effectiveness of new strategies for reducing losses of donors in cases of false positives
Magalhães, Daniela Mendes dos Santos. "Fatores sócio-demográficos e antecedentes obstétricos relacionados à sífilis na gestação em uma amostra de gestantes do Distrito Federal /". Botucatu : [s.n.], 2011. http://hdl.handle.net/11449/99203.
Pełny tekst źródłaBanca: Iracema de Mattos Paranhos Calderon
Banca: Maria do Socorro Nantua Evangelista
Resumo: A sífilis na gestação é um grave problema de saúde pública, responsável por altos índices de morbimortalidade intrauterina. Estima-se que leve, em pelo menos 50% das gestações acometidas, a desfechos perinatais adversos. Esses dados remetem à falta de controle das doenças sexualmente transmissíveis (DST) e à deficiência na assistência pré-natal. O objetivo deste estudo transversal foi conhecer o perfil sócio-demográfico e os antecedentes obstétricos das gestantes com VDRL reagentes no DF no ano de 2010. Verificou-se o percentual de gestantes que tiveram acesso ao pré-natal e foram inadequadamente tratadas de acordo com as recomendações do MS. Foram entrevistadas 67 gestantes/ puérparas notificadas no SINAN, em cinco maternidades públicas do DF e consultadas as informações do prontuário e cartão da gestante quando disponível. Foram avaliados dados sóciodemográficos, obstétricos, informações relacionadas ao diagnóstico e tratamento da gestante/puérpara e parceiro. Apenas 41,8% gestantes foram adequadamente tratadas e o principal motivo para a inadequação do tratamento foi a falta (83,6%) ou inadequação do tratamento do parceiro (88,1%). Foi constatada a necessidade de novo tratamento da gestante na maternidade por falta de documentação do tratamento realizado no pré-natal. Os dados demonstram que a qualidade do pré-natal recebido pela gestante não é suficiente para garantir o controle da sífilis congênita e o atingimento da meta de controle da doença
Abstract: Syphilis during pregnancy is a serious public health problem responsible for high rates of intrauterine mortality. It is estimated that in at least 50% of pregnancies affected, adverse perinatal outcomes happen. These findings reflect the lack of control of sexually transmitted diseases (STDs) and disability in prenatal care. The goal of this survey was to understand the epidemiological profile of women with VDRL reagents in the Federal District in 2010. The study verified the percentage of pregnant women who had access to prenatal care and were inadequately treated in accordance with the recommendations of the Ministry of Health. We interviewed 67 pregnant and postpartum women who reported to the SINAN, users of five public hospitals of the DF and consulted information from medical records and from prenatal care charts, when available. Data were collected on sociodemographic, obstetric, information related to diagnosis and treatment of pregnant and puerperal women and their partners. Only 28 (41.8%) patients were adequately treated and the main reason for inadequacy was the lack of treatment (83.6%) or inadequate treatment of the partner (88.1%). The study demonstrated the need for new treatment of the mother at the hospital for lack of documentation of the treatment in prenatal care. Our data demonstrates that the quality of prenatal care received by pregnant women is not sufficient to ensure control of congenital syphilis and reaching the goal of controlling the disease
Mestre
RIVAS, RUBEN. "Les gommes syphilitiques cerebrales : a propos d'une observation". Clermont-Ferrand 1, 1988. http://www.theses.fr/1988CLF13030.
Pełny tekst źródłaQuemar-Huilizen, Anne. "Conceptions actuelles du dépistage et de traitement de la syphilis de l'oreille : à propos de 4 observations". Nantes, 1985. http://www.theses.fr/1985NANT3393.
Pełny tekst źródłaБарановская, Ю. А., i М. Н. Лебедюк. "Эпидемиология сифилиса и гонореи у несовершеннолетних лиц Одесской области". Thesis, Издательство СумГУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/11308.
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