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Artykuły w czasopismach na temat "Synthèse de peptides"
Kraus, Jean Louis. "Synthèse d'azamacrocycles polysubstitués par des peptides biologiquement actifs". Journal of Heterocyclic Chemistry 22, nr 5 (wrzesień 1985): 1307–12. http://dx.doi.org/10.1002/jhet.5570220532.
Pełny tekst źródłaDuvallet, Emilie, Mathilde Boulpicante i Sébastien Apcher. "Synthèse des peptides antigéniques du CMH-I dans le noyau". médecine/sciences 30, nr 3 (marzec 2014): 229–31. http://dx.doi.org/10.1051/medsci/20143003002.
Pełny tekst źródłaLE FLOC’H, N., i B. SEVE. "Le devenir des protéines et des acides aminés dans l’intestin du porc : de la digestion à l’apparition dans la veine porte". INRAE Productions Animales 13, nr 5 (22.10.2000): 303–14. http://dx.doi.org/10.20870/productions-animales.2000.13.5.3798.
Pełny tekst źródłaSalvadori, S. "Peptides opioides: synthèse et propriétés biologiques d'hexapeptides apparents à la dermorphine". European Journal of Medicinal Chemistry 25, nr 2 (marzec 1990): 171–77. http://dx.doi.org/10.1016/0223-5234(90)90025-x.
Pełny tekst źródłaRousseau, F., V. Fuentes, C. Corbel, E. Bissac, F. Eb i J. Orfila. "Intérêt des peptides de synthèse dans le sérodiagnostic d'infections à Chlamydia". La Revue de Médecine Interne 17 (styczeń 1995): S107. http://dx.doi.org/10.1016/0248-8663(96)86610-0.
Pełny tekst źródłaMichel, Andre G., Chakib Ameziane-Hassani, Gaston Boulay i Gilles Lajoie. "Étude structurale de la liaison thioamide: Synthèse et conformation de dérivés de la thioalanine et de la thioglycine". Canadian Journal of Chemistry 67, nr 8 (1.08.1989): 1312–18. http://dx.doi.org/10.1139/v89-202.
Pełny tekst źródłaCollet, C., S. Lamandé-Langle, F. Chrétien, F. Maskali, S. Poussier, P. Y. Marie, G. Karcher i Y. Chapleur. "Synthèse de nouveaux [18F]fluoro-sucres pour le radiomarquage de peptides : application en imagerie TEP". Médecine Nucléaire 38, nr 3 (maj 2014): 159. http://dx.doi.org/10.1016/j.mednuc.2014.03.115.
Pełny tekst źródłaZineddine, H., M. Asso, R. Panossian, M. Guiliano i D. Benlian. "Synthèse et structure de complexes d'ions métalliques et de peptides à résidus aspartyl et tyrosyl". Journal of Molecular Structure 192, nr 1-2 (styczeń 1989): 95–106. http://dx.doi.org/10.1016/0022-2860(89)87009-7.
Pełny tekst źródłaRuzycki, Shannon Marie, i Michael Prystajecky. "Point-Counterpoint: Perioperative Cardiac Biomarkers". Canadian Journal of General Internal Medicine 14, nr 4 (19.11.2019): e14-e22. http://dx.doi.org/10.22374/cjgim.v14i4.347.
Pełny tekst źródłaRauscher, A., P. Baumgartner, F. Lacoeuille, A. Cahouet-Vannier, C. Ansquer, C. Rousseau, F. Kraeber-Bodéré i A. Faivre-Chauvet. "Comparaison de deux techniques de pré-purification des éluats de 68GA pour le marquage de peptides par automate de synthèse". Médecine Nucléaire 38, nr 3 (maj 2014): 160–61. http://dx.doi.org/10.1016/j.mednuc.2014.03.120.
Pełny tekst źródłaRozprawy doktorskie na temat "Synthèse de peptides"
Zerkout, Saïd. "Synthèse d'hydrazino peptides". Vandoeuvre-les-Nancy, INPL, 1994. http://www.theses.fr/1994INPL052N.
Pełny tekst źródłaTroalen, Frédéric. "Utilisation de la synthèse peptidique en immunochimie : application à l'étude de protéines présentant différents niveaux d'organisation structurale". Paris 5, 1989. http://www.theses.fr/1989PA05P618.
Pełny tekst źródłaMcMath, Andrew. "Synthèse d'analogues cyclopropaniques de peptides". Paris 5, 1997. http://www.theses.fr/1997PA05P608.
Pełny tekst źródłaPavlov, Nikola. "Synthèse asymétrique d’analogues de β2-tryptophane et application en synthèse peptidique". Thesis, Montpellier 2, 2011. http://www.theses.fr/2011MON20186/document.
Pełny tekst źródłaTryptophan, an essential amino acid, both functions as a building block in protein biosynthesis and as a biochemical precursor. It is abundantly found in most biologically active peptides that exhibit various physiological properties in particular hormonal and antimicrobial activities. Some of its natural derivatives like serotonin, tryptamine, and also unnatural derivatives such as sumatriptan, have neurophysiologic effects. Tryptophan analogues are also important building blocks for the synthesis of peptidomimetics, natural products and biologically active compounds. Another important property of tryptophan and tryptophan analogues is related to the fluorescence of the indole ring that can be used to study conformational changes in protein and in protein-membrane interactions. The asymmetric Friedel-Crafts alkylation of various indoles with a chiral nitroacrylate provides optically active beta-tryptophan analogues after reduction of the nitro group and removal of the chiral auxiliary. This reaction generally occurs in good yield and high diastereoselectivity (up to 90:10). We have established a new route to prepare enantiopure beta-tryptophan analogues ((S)-2-indolyl-beta-alanines). We showed that beta-nitroacrylate (R)-2 is a good chiral auxiliary for asymmetric Friedel-Crafts alkylation of indoles. (R)-2-indolyl--alanines were obtained by the same synthetic route by using the chiral compound (S)-2. beta-tryptophan analogues are delivered in their N-Fmoc-protected form, ready to use for instance in solid phase peptide synthesis, which is one of the most popular method for peptide synthesis. This study provides a new example of asymmetric beta-tryptophan analogues preparation and further studies concerning their applications in medicinal chemistry and in organic synthesis are now in progress
Charbonnier-Gérardin, Christine. "Nouvelles applications en synthèse des acides 2-dialkylphosphonoalcanoique : préparation de phosphonopeptides inhibiteurs de peptidases". Nancy 1, 1991. http://www.theses.fr/1991NAN10063.
Pełny tekst źródłaBeretta, Margaux. "Synthèse d'analogues de la gougérotine à visée antifongique". Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS484/document.
Pełny tekst źródłaIn the current context of the world demographic explosion, agricultural yields need to be as high as possible. The use of efficient and environment friendly pesticides has therefore become essential. In the framework of the discovery of new compounds, natural products remain an important source of inspiration. Among them, we focused on gougerotin, a peptidylnucleoside isolated from a bacteria in the 60’s which possess a broad spectrum of biologic activities. In order to improve antifungal potential and decrease the phytotoxicity of gougerotin, several analogues have been synthesized replacing the natural nucleobase. N-glycosylation is one of the key-reaction in peptidylnucleoside synthesis. During the synthesis of the analogues, a study of the N-glycosylation was carried out with three different donors and several bases. Protectives tests were realized with many pathogens to evaluate antifungal activity of our compounds and a structure-activity relationship was established
Merhi, Ghada. "Synthèse et évaluation de nouveaux muramyl peptides". Paris 11, 1996. http://www.theses.fr/1996PA114809.
Pełny tekst źródłaBarra, Marielle. "Synthèse et étude de bêta-peptides glycoconjugués". Clermont-Ferrand 2, 2009. http://www.theses.fr/2009CLF21998.
Pełny tekst źródłaGiribaldi, Julien. "Synthèse de peptides bioactifs inspirés des venins". Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTS124.
Pełny tekst źródłaNatural extracts such as animal venoms are an important source of bioactive peptides for therapeutic purposes. Peptides derived from venoms currently used in medicine include Eptifibatide, an antiplatelet drug developed from echistatin, a toxin isolated from a viper, Ziconotide, a potent analgesic identified in the venom of a cone snail and Exenatide , a glucagon-like peptide 1 receptor agonist isolated from the saliva of the Gila monster and used for the treatment of type 2 diabetes. These disulfide-rich venom peptides exhibit a constrained three-dimensional structure and increased plasma stability compared to linear peptides. Conservation of prey / predator receptors with human receptors makes venom peptides a unique source of lead compounds for the design of pharmacological tools and therapeutic compounds. It is estimated that less than 1% of the venom peptides have been pharmacologically characterized. Thus, this project aims to explore the pharmacology of novel venom-isolated peptides using solid phase peptide synthesis based on Fmoc chemistry (Fmoc-SPPS) as well as oxidative and regioselective folding strategies to produce the correctly folded and biologically active peptide for subsequent characterization. While the first part of this project is dedicated to the synthesis of linear and disulfide-poor venom peptides, the second part will be dedicated to the synthesis of disulfide-rich peptides via oxidative and regioselective folding strategies. Finally, we will use proteomic approaches integrated with transcriptomic data for the identification of new sequences from venoms. Overall, this project provides a better understanding of the pharmacology of venom peptides and identifies leads for the development of new pharmacological tools and potential drug candidates
Alcaro, Maria Claudia. "Synthèse de peptides contraints cycliques et linéaires". Cergy-Pontoise, 2003. http://www.theses.fr/2003CERG0178.
Pełny tekst źródłaMany researches have recently demonstrated the importance of peptides for medicinal chemistry. The development of new drugs based on peptide modification is an important goal, as peptides can mimic proteins. The synthesis of constrained peptides represents a very efficient strategy for structure-activity relationship studies, in order to characterize the protein active site. During this thesis, peptides were modified introducing different constraints. In the first part of these studies, a series of unnatural amino acids were synthesized. These amino acids were introduced in the peptide sequence of the potent BK antagonist HOE 140. These peptide analogues were synthesized by a solid-phase approach and were then tested for their biological activity. In the second part of this thesis an efficient solid-phase strategy for the synthesis of constrained cyclopeptides was set up
Książki na temat "Synthèse de peptides"
Chemistry of peptide synthesis. Boca Raton: Taylor & Francis/CRC Press, 2006.
Znajdź pełny tekst źródłaBenoiton, N. Leo. Chemistry of peptide synthesis. Boca Raton: Taylor & Francis/CRC Press, 2006.
Znajdź pełny tekst źródłaC, Sheppard R., red. Solid phase peptide synthesis: A practical approach. Oxford, England: IRL Press at Oxford University Press, 1989.
Znajdź pełny tekst źródłaBodanszky, Miklos. Principles of peptide synthesis. Wyd. 2. Berlin: Springer-Verlag, 1993.
Znajdź pełny tekst źródła1925-, Bodanszky A., red. The practice of peptide synthesis. Wyd. 2. Berlin: Springer-Verlag, 1994.
Znajdź pełny tekst źródłaBodanszky, M. Principles of peptide synthesis. Wyd. 2. Berlin: Springer-Verlag, 1993.
Znajdź pełny tekst źródłaAmino acid and peptide synthesis. Oxford: Oxford University Press, 1992.
Znajdź pełny tekst źródłaM, Kazmierski Wieslaw, red. Peptidomimetics protocols. Totowa, NJ: Humana Press, 1999.
Znajdź pełny tekst źródłaThe chemical synthesis of peptides. Oxford: Clarendon Press, 1991.
Znajdź pełny tekst źródłaservice), ScienceDirect (Online, red. Complex enzymes in microbial natural product biosynthesis: Polyketides, aminocoumarins and carbohydrates. London: Academic, 2009.
Znajdź pełny tekst źródłaCzęści książek na temat "Synthèse de peptides"
Rivier, J. E., A. G. Craig, E. Mahe, A. Rabinovich, D. Kirby, R. Kaiser, J. Porter i in. "Total Syntheses". W Peptides, 1081–84. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_366.
Pełny tekst źródłaKolasa, Teodozyj, i Marvin J. Miller. "Studies related to the syntheses of pseudobactin". W Peptides, 232–35. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_69.
Pełny tekst źródłaChen, Yun-Neng, Hisaya Kuroda, Yukako Itahara, Takushi X. Watanabe, Terutoshi Kimura i Shumpei Sakakibara. "Syntheses of iberiotoxin and its related peptides". W Peptides, 269–72. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_79.
Pełny tekst źródłaKodama, Hiroaki, Masaya Miyazaki, Michio Kondo, Kazuyasu Sakaguchi, Charles H. Stammer i Hao-Chia Chen. "Syntheses and chemotactic activities of [2,3-methanophenylalanine3]chemotactic peptides". W Peptides, 423–24. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_157.
Pełny tekst źródłaBalasubramaniam, A., S. Sheriff, M. Borchers, V. Renugopalakrishnan, M. Stein, W. T. Chance i J. E. Fischer. "Human and rat amylin: Syntheses, structures and binding sites". W Peptides, 66–68. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_19.
Pełny tekst źródłaBarany, George, Fernando Albericio, Sara Biancalana, Susan L. Bontems, Jane L. Chang, Ramon Eritja, Marc Ferrer i in. "Biopolymer syntheses on novel polyethylene glycol-polystyrene (PEG-PS) graft supports". W Peptides, 603–4. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_238.
Pełny tekst źródłaBeusen, D. D., L. M. McDowell, A. Schmidt, E. R. Cohen i J. Schaefer. "Solid-state NMR determination of the geometry of substrate and inhibitor bound to EPSP synthase". W Peptides, 760–62. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_252.
Pełny tekst źródłaEchner, H., P. Yialouris, A. A. Haritos, G. Grübler i W. Voelter. "Structures and syntheses of thymosin β11 and β12". W Peptides 1992, 751–52. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1470-7_344.
Pełny tekst źródłaBeyermann, M., P. Henklein, Annerose Klose, R. Sohr i M. Bienert. "Effect of tertiary amine on carbodiimide-mediated peptide syntheses". W Peptides 1990, 59–61. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3034-9_21.
Pełny tekst źródłaKiso, Yoshiaki, Makoto Yoshida, Yoichi Fujiwara, Tooru Kimura, Kenichi Akaji i Haruaki Yajima. "Syntheses of Natriuretic Peptides Using a New S-Protecting Group, S-Trimethylacetamidomethyl (Tacm) Group". W Peptides, 27–37. Boston, MA: Birkhäuser Boston, 1994. http://dx.doi.org/10.1007/978-1-4615-8176-5_3.
Pełny tekst źródłaStreszczenia konferencji na temat "Synthèse de peptides"
Tuháčková, Zdena, Eva Šloncová, Jan Hlaváček, Vlasta Sovová i Jiří Velek. "Activation of the protein kinase B and glycogen synthase kinase-3 signalling pathway during transient differentiation of human colon cancer HT-29 cells". W VIth Conference Biologically Active Peptides. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199903019.
Pełny tekst źródłaSong, Yan, Zheng Wang, Hong-Li Lv, Zhen Guo i Xiu-Kun Lin. "Optimization of mRNA Display for Identifying Peptides that Bind with Thymidylate Synthase RNA". W 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5163156.
Pełny tekst źródłaSibrian-Vazquez, Martha, Timothy J. Jensen, Robert P. Hammer i M. Graça H. Vicente. "Syntheses and cellular studies of water soluble porphyrin-peptide conjugates". W Biomedical Optics (BiOS) 2007, redaktor David Kessel. SPIE, 2007. http://dx.doi.org/10.1117/12.698445.
Pełny tekst źródłaLopez, Alexandra C., Qian Chen, Brittany L. Deiling, Edward S. Iames, Robert Barsotti i Lindon H. Young. "The Effects of Modulating Endothelial Nitric Oxide Synthase (eNOS) Activity and Coupling in Extracorporeal Shock Wave Lithotripsy (ESWL)". W The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.058.
Pełny tekst źródłaCorreale, Pierpaolo, Pierpaolo Pastina, Cirino Botta, Serena Apollinari, Elena Bestoso, Antonella Fioravanti, Giacomo Maria Guidelli i in. "Abstract LB-229: Treatment of advanced cancer patients with a newest poly-epitope peptide vaccine to the thymidylate synthase(TSPP): a phase Ib (TSPP/VAC1) trial". W Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-lb-229.
Pełny tekst źródłaCorreale, Pierpaolo, Cirino Botta, Elodia Claudia Martino, Valerio Nardone, Cristina Ulivieri, Claudia Gandolfo, Tatiana Cosima Baldari i in. "Abstract 2232: Immune-inflammatory markers predict the outcome of metastatic colorectal cancer patients treated with the thymidylate synthase poly-epitope peptide (TSPP) vaccine: results from a multi-arm TSPP/VAC phase Ib program". W Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2232.
Pełny tekst źródłaAgüero-Chapin, Guillermin, Enrique García-Hernández, Yasser Ruiz-Blanco, Luis Ávila-Barrientos, Enrique Hernández-García i Agostinho Antunes. "Engineering protein fragments via evolutionary and protein-protein interaction algorithms: <em>De novo</em> design of peptide inhibitors for F<sub>O</sub>F<sub>1</sub>-ATP synthase". W MOL2NET'22, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 8th ed. - MOL2NET: FROM MOLECULES TO NETWORKS. Basel, Switzerland: MDPI, 2022. http://dx.doi.org/10.3390/mol2net-08-13936.
Pełny tekst źródłaRaporty organizacyjne na temat "Synthèse de peptides"
Cytryn, Eddie, Mark R. Liles i Omer Frenkel. Mining multidrug-resistant desert soil bacteria for biocontrol activity and biologically-active compounds. United States Department of Agriculture, styczeń 2014. http://dx.doi.org/10.32747/2014.7598174.bard.
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