Artykuły w czasopismach na temat „Somatic gain of mutation STAT3”
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Koskela, Hanna, Samuli Eldfors, Henrikki Almusa, Emma Andersson, Pekka Ellonen, Henrik Edgren, Pirjo Koistinen i in. "Recurrent Missense Mutations in the STAT3 Gene in LGL Leukemia Provide Insights to Pathogenetic Mechanisms and Suggest Potential Diagnostic and Therapeutic Applications". Blood 118, nr 21 (18.11.2011): 936. http://dx.doi.org/10.1182/blood.v118.21.936.936.
Pełny tekst źródłaChomczynski, Peter W., Michael J. Clemente, Srinivasa Reddy Sanikommu, Alek d. Nielsen, Cassandra M. Hirsch, Hanna Rajala, Mikkael A. Sekeres i in. "Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals". Blood 128, nr 22 (2.12.2016): 2731. http://dx.doi.org/10.1182/blood.v128.22.2731.2731.
Pełny tekst źródłaLesmana, Harry, Marcela Popescu, Sara Lewis, Sushree Sangita Sahoo, Charnise Goodings-Harris, Mihaela Onciu, John Kim Choi, Clifford Takemoto, Kim E. Nichols i Marcin Wlodarski. "Germline Gain-of-Function JAK3 Mutation in Familial Chronic Lymphoproliferative Disorder of NK Cells". Blood 136, Supplement 1 (5.11.2020): 9–10. http://dx.doi.org/10.1182/blood-2020-142078.
Pełny tekst źródłaRajala, Hanna L. M., Thomas Olson, Sonja Lagström, Pekka Ellonen, Syed Arshi Uz Zaman, Emma I. Andersson, Michael J. Clemente i in. "Multiple STAT3 Mutations In Different Lymphocyte Clones Of Large Granular Lymphocytic Leukemia Patients". Blood 122, nr 21 (15.11.2013): 2559. http://dx.doi.org/10.1182/blood.v122.21.2559.2559.
Pełny tekst źródłaNabhani, Schafiq, Hagit Miskin, Cyrill Schipp, Dan Harlev, Shoshana Revel-Vilk, Michael Gombert, Sebastian Ginzel, Arndt Borkhardt, Polina Stepensky i Ute Fischer. "Activating Mutation of STAT3 Protects Lymphocytes from Apoptosis and Leads to a Clinical Phenotype Resembling the Autoimmune Lymphoproliferative Syndrome". Blood 126, nr 23 (3.12.2015): 2218. http://dx.doi.org/10.1182/blood.v126.23.2218.2218.
Pełny tekst źródłaWang, T. Tiffany, Jun Yang, Shubha Dighe, Matthew W. Schmachtenberg, Nathan T. Leigh, Emily Farber, Suna Onengut-Gumuscu i in. "Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation". Cancers 12, nr 1 (3.01.2020): 126. http://dx.doi.org/10.3390/cancers12010126.
Pełny tekst źródłaKim, Daehong, Mikko Myllymäki, Matti Kankainen, Timo Jarvinen, Giljun Park, Roberta Bruhn, Edward L. Murphy i Satu Mustjoki. "Somatic STAT3 Mutations in CD8+ T Cells of HTLV-2 Positive Blood Donors". Blood 138, Supplement 1 (5.11.2021): 3133. http://dx.doi.org/10.1182/blood-2021-146326.
Pełny tekst źródłaKunter, Ghada M., Fulu Liu, Maxwell Krem i Daniel Link. "G-CSF Receptor Mutations Found in Patients with Severe Congenital Neutropenia Confer a Strong Competitive Growth Advantage at the Hematopoietic Stem Cell Level That Is Mediated by STAT5 Activation." Blood 108, nr 11 (16.11.2006): 632. http://dx.doi.org/10.1182/blood.v108.11.632.632.
Pełny tekst źródłaMailloux, Adam W., Jeff Painter, Eric Padron, Thomas P. Loughran i Pearlie K. Epling-Burnette. "Common γ Chain (γc) Cytokine Hypersensitivity Leads To T-Cell Homeostatic Deregulation Independent Of STAT3 Mutation In Large Granular Lymphocyte Leukemia". Blood 122, nr 21 (15.11.2013): 1628. http://dx.doi.org/10.1182/blood.v122.21.1628.1628.
Pełny tekst źródłaPastore, Friederike, Aishwarya Krishnan, Henrik M. Hammarén, Olli Silvennoinen, Benedict Yan i Ross L. Levine. "JAK2S523L, a novel gain-of-function mutation in a critical autoregulatory residue in JAK2V617F− MPNs". Blood Advances 4, nr 18 (21.09.2020): 4554–59. http://dx.doi.org/10.1182/bloodadvances.2019001283.
Pełny tekst źródłaMasle-Farquhar, Etienne, Kathryn Payne, Mandeep Singh, Geetha Rao, Ghamdan Al-Eryani, Christopher Jara, Katherine Jackson i in. "The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cells". Journal of Immunology 204, nr 1_Supplement (1.05.2020): 142.35. http://dx.doi.org/10.4049/jimmunol.204.supp.142.35.
Pełny tekst źródłaMilosevic Feenstra, Jelena D., Harini Nivarthi, Heinz Gisslinger, Emilie Leroy, Elisa Rumi, Ilyas Chachoua, Klaudia Bagienski i in. "Whole Exome Sequencing Identifies Novel MPL and JAK2 M utations in Triple Negative Myeloproliferative Neoplasms". Blood 126, nr 23 (3.12.2015): 606. http://dx.doi.org/10.1182/blood.v126.23.606.606.
Pełny tekst źródłaLukes, Julius, Eliska Potuckova, Julia Starkova, Jan Stary, Jan Zuna, Jan Trka i Marketa Zaliova. "Chromosome 21 Gain Is Dispensable for Transient Myeloproliferative Disorder (TMD) Development". Blood 132, Supplement 1 (29.11.2018): 2764. http://dx.doi.org/10.1182/blood-2018-99-112078.
Pełny tekst źródłaViganò, Elena, Gerben Duns, Daisuke Ennishi, Randy D. Gascoyne, Ryan D. Morin, David W. Scott i Christian Steidl. "Recurrent IL4R Somatic Mutations in Diffuse Large B-Cell Lymphoma Lead to an Altered Gene Expression Profile and Changes in Tumor Microenvironment Composition". Blood 132, Supplement 1 (29.11.2018): 669. http://dx.doi.org/10.1182/blood-2018-99-110473.
Pełny tekst źródłaGerbaulet, Alexander, Claudia Wickenhauser, Julia Scholten, Katrin Peschke, Sebastian Drube, Hans-Peter Horny, Thomas Kamradt i in. "Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit". Blood 117, nr 6 (10.02.2011): 2012–21. http://dx.doi.org/10.1182/blood-2008-11-189605.
Pełny tekst źródłaManshouri, Taghi, Zeev Estrov, Alfonso Quintas-Cardama, Jorge Cortes, Francis Giles, David Harris, Waldemar Priebe, Hagop Kantarjian i Srdan Verstovsek. "WP1066 Inhibits Growth of Human Cells Carrying the JAK2 V617F Mutation." Blood 108, nr 11 (16.11.2006): 4885. http://dx.doi.org/10.1182/blood.v108.11.4885.4885.
Pełny tekst źródłaGeorgescu, Maria-Magdalena. "TAMI-32. TEMPOROSPATIAL INVASION AND GENETIC EVOLUTION FROM INFRATENTORIAL TO SUPRATENTORIAL COMPARTMENT IN DIFFUSE MIDLINE GLIOMA". Neuro-Oncology 22, Supplement_2 (listopad 2020): ii220. http://dx.doi.org/10.1093/neuonc/noaa215.920.
Pełny tekst źródłaLee, Jeong Seok, Yohan An, Christopher J. Yoon, Jeong Yeon Kim, Kyung Hwan Kim, Alexandra F. Freeman, Jae-Joon Yim i in. "Germline gain-of-function mutation of STAT1 rescued by somatic mosaicism in immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like disorder". Journal of Allergy and Clinical Immunology 145, nr 3 (marzec 2020): 1017–21. http://dx.doi.org/10.1016/j.jaci.2019.11.028.
Pełny tekst źródłaMikulasova, Aneta, Brian A. Walker, Christopher P. Wardell, Eileen M. Boyle, Alexander Murison, Zuzana Kufova, Ludek Pour, Petr Kuglik, Roman Hajek i Gareth J. Morgan. "Somatic Mutation Spectrum in Monoclonal Gammopathy of Undetermined Significance Compared to Multiple Myeloma". Blood 124, nr 21 (6.12.2014): 3346. http://dx.doi.org/10.1182/blood.v124.21.3346.3346.
Pełny tekst źródłaNagata, Yasunobu, Terukazu Enami, Kenji Kontani, Keisuke Kataoka, Mamiko Sakata-Yanagimoto, Akira Kitanaka, Aiko Sato i in. "Novel Biological Effects and Distinct Patterns of Rhoa Mutations in Adult T-Cell Leukemia/Lymphoma and Angioimmunoblastic T Cell Lymphoma". Blood 124, nr 21 (6.12.2014): 2215. http://dx.doi.org/10.1182/blood.v124.21.2215.2215.
Pełny tekst źródłaNothiger, R., M. Jonglez, M. Leuthold, P. Meier-Gerschwiler i T. Weber. "Sex determination in the germ line of Drosophila depends on genetic signals and inductive somatic factors". Development 107, nr 3 (1.11.1989): 505–18. http://dx.doi.org/10.1242/dev.107.3.505.
Pełny tekst źródłaNiemöller, Christoph, Sabine Bleul, Nadja Blagitko-Dorfs, Christine Greil, Kenichi Yoshida, Rainer Claus, Dietmar Pfeifer, Seishi Ogawa, Michael Lübbert i Heiko Becker. "Single Cell Genotyping of Inv(16) AML in CBL Mutated Clonal Hematopoiesis Characterizes Clonal Architecture and Evolution of Exome Sequencing-Identified Mutations in the Protein Tyrosine Phosphatase Ptprt and Other Genes". Blood 126, nr 23 (3.12.2015): 3834. http://dx.doi.org/10.1182/blood.v126.23.3834.3834.
Pełny tekst źródłaSingh, Manu, Raymond Louie, Claire Milthopre, Thiruni Adikari, Melinda Hardy, Megan Faulks, Matt Field i in. "Multi-omic profiling in coeliac disease reveals somatic driver mutations in rogue T cell clones". Journal of Immunology 210, nr 1_Supplement (1.05.2023): 234.12. http://dx.doi.org/10.4049/jimmunol.210.supp.234.12.
Pełny tekst źródłaMaterna-Kiryluk, Anna, Agnieszka Pollak, Karol Gawalski, Aleksandra Szczawinska-Poplonyk, Zuzanna Rydzynska, Anna Sosnowska, Bożena Cukrowska i in. "Mosaic IL6ST variant inducing constitutive GP130 cytokine receptor signaling as a cause of neonatal onset immunodeficiency with autoinflammation and dysmorphy". Human Molecular Genetics 30, nr 3-4 (30.01.2021): 226–33. http://dx.doi.org/10.1093/hmg/ddab035.
Pełny tekst źródłaMakishima, Kenichi, Kashima Yukie, Yuta Kuze, Sakurako Suma, Yoshiaki Abe, Yasuhito Suehara, Tatsuhiro Sakamoto i in. "Investigation of Clonal Hematopoiesis in New Japanese Cohort". Blood 142, Supplement 1 (28.11.2023): 5608. http://dx.doi.org/10.1182/blood-2023-181324.
Pełny tekst źródłaAl-Dewik, Nader I., Bruno Cassinat, Jean-Jacques Kiladjian, Alexander Knuth i Mohamed A. Yassin. "Targeted Exome Sequencing Identifies Novel Mutations in Familial Myeloproliferative Neoplasms Patients in the State of Qatar". Blood 124, nr 21 (6.12.2014): 5570. http://dx.doi.org/10.1182/blood.v124.21.5570.5570.
Pełny tekst źródłaStockklausner, Clemens, Christin Maria Duffert, Ziwei Zhou, Anne Christine Klotter, Isabelle Nadine Kuhlee i Andreas E. Kulozik. "Mpl Gain-of-Function Mutations Can be Classified By Differential Subcellular Processing, Molecular Mechanisms, Mode of Inheritance and Clinical Impact". Blood 126, nr 23 (3.12.2015): 1634. http://dx.doi.org/10.1182/blood.v126.23.1634.1634.
Pełny tekst źródłaSanders, Mathijs A., Annelieke Zeilemakers, Jasper Koenders, Remco Hoogenboezem, François Kavelaars, Rob Henderson, Bob Lowenberg i Peter J. M. Valk. "The Gene Encoding Nuclear Erythroid Factor 2 (NFE2) Is Recurrently Mutated in Acute Myeloid Leukemia". Blood 120, nr 21 (16.11.2012): 1392. http://dx.doi.org/10.1182/blood.v120.21.1392.1392.
Pełny tekst źródłaPrzychodzen, Bartlomiej, i Sandra Paulina Smieszek. "Preclinical evaluation of JAK2 specific investigational oligonucleotide for the treatment of MDS/PV." JCO Global Oncology 9, Supplement_1 (sierpień 2023): 122. http://dx.doi.org/10.1200/go.2023.9.supplement_1.122.
Pełny tekst źródłaCoppe, Alessandro, Emma I. Andersson, Andrea Binatti, Vanessa R. Gasparini, Sabrina Bortoluzzi, Michael J. Clemente, Marco Herling, Jaroslaw P. Maciejewski, Satu Mustjoki i Stefania Bortoluzzi. "Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia". Blood 128, nr 22 (2.12.2016): 4117. http://dx.doi.org/10.1182/blood.v128.22.4117.4117.
Pełny tekst źródłaTakeda, Yusuke, Chiaki Nakaseko, Hiroaki Tanaka, Masahiro Takeuchi, Makiko Yui, Atsunori Saraya, Satoru Miyagi i in. "Direct Activation of STAT5 by TEL-Lyn Fusion Protein Promotes Induction of Myeloproliferative Neoplasms with Myelofibrosis". Blood 116, nr 21 (19.11.2010): 4114. http://dx.doi.org/10.1182/blood.v116.21.4114.4114.
Pełny tekst źródłaMambet, Cristina, Jean-Philippe Defour, Olga Babosova, Emilie Leroy, Laura Necula, Oana Stanca, Aurelia Tatic i in. "JAK2 R1063H Variant Enhances V617F Constitutive Signaling and Favors Development of Essential Thrombocythemia with Increased Hemoglobin and Neutrophils". Blood 132, Supplement 1 (29.11.2018): 3066. http://dx.doi.org/10.1182/blood-2018-99-117019.
Pełny tekst źródłaPrzychodzen, Bart, Sandra P. Smieszek, Christos M. Polymeropoulos, Mihael Polymeropoulos i Gunther Birznieks. "Preclinical Evaluation of JAK2 Specific Investigational Oligonucleotide for the Treatment of MPNs". Blood 142, Supplement 1 (28.11.2023): 7138. http://dx.doi.org/10.1182/blood-2023-183035.
Pełny tekst źródłaLukes, Julius, Petr Danek, Oriol Alejo, Eliska Potuckova, Ondrej Gahura, Dirk Heckl, Julia Starkova i in. "Characterization of a Novel JAK1 Pseudokinase Mutation in the First Case of Trisomy 21-Independent GATA1-Mutated Transient Abnormal Myelopoiesis". Blood 134, Supplement_1 (13.11.2019): 4208. http://dx.doi.org/10.1182/blood-2019-122168.
Pełny tekst źródłaHartert, Keenan, Saber Tadros, Alyssa Bouska, Dalia Moore, Christine Pak, Tayla Heavican, Chih Long Liu i in. "DNA Copy Number Gains of TCF4 (E2-2) Are Associated with Poor Outcome in Diffuse Large B-Cell Lymphoma". Blood 128, nr 22 (2.12.2016): 2686. http://dx.doi.org/10.1182/blood.v128.22.2686.2686.
Pełny tekst źródłaChapuy, Bjoern, Chip Stewart, Andrew Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel Kenneth Griffin i in. "Comprehensive Genomic Analysis of Primary Mediastinal B-Cell Lymphoma". Blood 132, Supplement 1 (29.11.2018): 1564. http://dx.doi.org/10.1182/blood-2018-99-118135.
Pełny tekst źródłaPapayannidis, Cristina, Anna Ferrari, Stefania Paolini, Carmen Baldazzi, Chiara Sartor, Abbenante maria Chiara, Giovanni Marconi i in. "Very Poor Outcome and Chemoresistance of Acute Myeloid Leukemia Patients with TP53 Mutations: Correlation with Complex Karyotype and Clinical Outcome". Blood 124, nr 21 (6.12.2014): 484. http://dx.doi.org/10.1182/blood.v124.21.484.484.
Pełny tekst źródłaGopisetty, Apurva, Aniello Federico, Didier Surdez, Yasmine Iddir, Sakina Zaidi, Alexandra Saint-Charles, Joshua Waterfall i in. "Abstract 234: ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput in vivo testing". Cancer Research 83, nr 7_Supplement (4.04.2023): 234. http://dx.doi.org/10.1158/1538-7445.am2023-234.
Pełny tekst źródłaCasolari, Debora A., Diana G. Iarossi, Carolyn M. Butcher, Sarah C. Bray, Wendy T. Parker, Chris N. Hahn, Susan Branford i in. "Aberrant Activation of Epidermal Growth Factor Receptor in MPN May Respond to the Kinase Inhibitor Gefitinib". Blood 124, nr 21 (6.12.2014): 1882. http://dx.doi.org/10.1182/blood.v124.21.1882.1882.
Pełny tekst źródłaPalomero, Teresa, Lucile Couronne, Hossein Khiabanian, Mi-Yeon Kim, Alberto Ambesi, Zachary Carpenter, Francesco Abate i in. "Recurrent Rhoa Mutations In Peripheral T-Cell Lymphoma". Blood 122, nr 21 (15.11.2013): 846. http://dx.doi.org/10.1182/blood.v122.21.846.846.
Pełny tekst źródłaYen, Katharine, Fang Wang, Jeremy Travins, Yue Chen, Hua Yang, Kim Straley, Sung Choe i in. "AG-221 Offers a Survival Advantage In a Primary Human IDH2 Mutant AML Xenograft Model". Blood 122, nr 21 (15.11.2013): 240. http://dx.doi.org/10.1182/blood.v122.21.240.240.
Pełny tekst źródłaBiancon, Giulia, Poorval Joshi, Torben Hunck, Yimeng Gao, Valentina Botti, Ashley Qin, Mukhtar Sadykov i in. "U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex". Blood 134, Supplement_1 (13.11.2019): 1230. http://dx.doi.org/10.1182/blood-2019-130759.
Pełny tekst źródłaAndersson, Emma I., Samuli Eldfors, Hanna L. M. Koskela, Pekka Ellonen, Thomas Olson, Andres Jerez, Michael J. Clemente i in. "Somatic PTPRT and ANGPT2 Mutations in Large Granulocyte Leukemia". Blood 120, nr 21 (16.11.2012): 1302. http://dx.doi.org/10.1182/blood.v120.21.1302.1302.
Pełny tekst źródłaSoekojo, Cinnie Yentia, Tae-Hoon Chung, Muhammad Shaheryar Furqan i Wee-Joo Chng. "Identifying the Genomic Profile of Functional High-Risk Multiple Myeloma Patients". Blood 136, Supplement 1 (5.11.2020): 51–52. http://dx.doi.org/10.1182/blood-2020-136553.
Pełny tekst źródłaWillekens, Christophe, Lucie Laplane, Tracy Dagher, Camélia Benlabiod, Catherine Lacout, Philippe Rameau, Cyril Catelain i in. "SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes". Blood 138, Supplement 1 (5.11.2021): 2544. http://dx.doi.org/10.1182/blood-2021-149757.
Pełny tekst źródłaSong, Jihyun, i Josef T. Prchal. "Ropeginterferon Alfa-2b Blunts Hyperactive JAK2 Activity in Polycythemia Vera and Essential Thrombocythemia". Blood 142, Supplement 1 (28.11.2023): 3162. http://dx.doi.org/10.1182/blood-2023-190172.
Pełny tekst źródłaMagee, Jeffrey A., Shaina Porter i Andrew Cluster. "FLT3-ITD Has Developmental Context Specific Effects on Hematopoiesis and Myeloid Leukemogenesis". Blood 126, nr 23 (3.12.2015): 843. http://dx.doi.org/10.1182/blood.v126.23.843.843.
Pełny tekst źródłaCline, Thomas W. "A FEMALE-SPECIFIC LETHAL LESION IN AN X-LINKED POSITIVE REGULATOR OF THE DROSOPHILA SEX DETERMINATION GENE, SEX-LETHAL". Genetics 113, nr 3 (1.07.1986): 641–63. http://dx.doi.org/10.1093/genetics/113.3.641.
Pełny tekst źródłaWang, Linghua, Sabina Swierczek, Kimberly Hickman, Soo-Jin Kim, David A. Wheeler i Josef Prchal. "Molecular Characterization Of Polycythemia Vera Based On The Relationship Of JAK2V617F and 9pUPD". Blood 122, nr 21 (15.11.2013): 1607. http://dx.doi.org/10.1182/blood.v122.21.1607.1607.
Pełny tekst źródłaMorgan, Elizabeth A., Mark N. Lee, Daniel J. DeAngelo, David P. Steensma, Richard M. Stone, Frank C. Kuo, Jon C. Aster, Christopher J. Gibson i R. Coleman Lindsley. "Systematic STAT3 Mutation Testing Identifies Patients with Unsuspected T-Cell Large Granular Lymphocytic Leukemia". Blood 128, nr 22 (2.12.2016): 919. http://dx.doi.org/10.1182/blood.v128.22.919.919.
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