Artykuły w czasopismach na temat „Small inhibitory compounds”
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Alvarez-Gonzalez, Juan Antonio, Robert Maul, Rahul M. Kohli i Patricia J. Gearhart. "Small molecule inhibitors of Activation-Induced Deaminase". Journal of Immunology 200, nr 1_Supplement (1.05.2018): 48.18. http://dx.doi.org/10.4049/jimmunol.200.supp.48.18.
Pełny tekst źródłaYan, Hua, Tomoko Chiba Mizutani, Nobuhiko Nomura, Tadakazu Takakura, Yoshihiro Kitamura, Hideka Miura, Masako Nishizawa, Masashi Tatsumi, Naoki Yamamoto i Wataru Sugiura. "A Novel Small Molecular Weight Compound with a Carbazole Structure That Demonstrates Potent Human Immunodeficiency Virus Type-1 Integrase Inhibitory Activity". Antiviral Chemistry and Chemotherapy 16, nr 6 (grudzień 2005): 363–73. http://dx.doi.org/10.1177/095632020501600603.
Pełny tekst źródłaAsai, Takashi, Tsutomu Takeuchi, Jeff Diffenderfer i L. David Sibley. "Identification of Small-Molecule Inhibitors of Nucleoside Triphosphate Hydrolase in Toxoplasma gondii". Antimicrobial Agents and Chemotherapy 46, nr 8 (sierpień 2002): 2393–99. http://dx.doi.org/10.1128/aac.46.8.2393-2399.2002.
Pełny tekst źródłaPatkar, Chinmay G., Martha Larsen, Michael Owston, Janet L. Smith i Richard J. Kuhn. "Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput Assay". Antimicrobial Agents and Chemotherapy 53, nr 10 (3.08.2009): 4103–14. http://dx.doi.org/10.1128/aac.00074-09.
Pełny tekst źródłaHan, Chun, Jiahong Ren, Feng Su, Xiaoqin Hu, Mengyao Li, Zhijun Wang i Lintao Wu. "Hybrids of Quinoline and Anilinopyrimidine: Novel EGFRT790M Inhibitors with Antiproliferative Activity against Non-Small Cell Lung Cancer Cell Lines". Anti-Cancer Agents in Medicinal Chemistry 20, nr 6 (14.06.2020): 724–33. http://dx.doi.org/10.2174/1871520620666200302113206.
Pełny tekst źródłaAbramić, Marija, i Dejan Agić. "Survey of Dipeptidyl Peptidase III Inhibitors: From Small Molecules of Microbial or Synthetic Origin to Aprotinin". Molecules 27, nr 9 (7.05.2022): 3006. http://dx.doi.org/10.3390/molecules27093006.
Pełny tekst źródłaNoueiry, Amine O., Paul D. Olivo, Urszula Slomczynska, Yi Zhou, Ben Buscher, Brian Geiss, Michael Engle i in. "Identification of Novel Small-Molecule Inhibitors of West Nile Virus Infection". Journal of Virology 81, nr 21 (22.08.2007): 11992–2004. http://dx.doi.org/10.1128/jvi.01358-07.
Pełny tekst źródłaLefas, Georgia, i George Chaconas. "High-Throughput Screening Identifies Three Inhibitor Classes of the Telomere Resolvase from the Lyme Disease Spirochete". Antimicrobial Agents and Chemotherapy 53, nr 10 (13.07.2009): 4441–49. http://dx.doi.org/10.1128/aac.00529-09.
Pełny tekst źródłaErcan-Fang, Nacide, Miriam R. Taylor, Judith L. Treadway, Carolyn B. Levy, Paul E. Genereux, E. Michael Gibbs, Virginia L. Rath, Younggil Kwon, Mary C. Gannon i Frank Q. Nuttall. "Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors". American Journal of Physiology-Endocrinology and Metabolism 289, nr 3 (wrzesień 2005): E366—E372. http://dx.doi.org/10.1152/ajpendo.00264.2004.
Pełny tekst źródłaYoo, Jihye, Darong Kim, Jiyoung Park, Young-Kook Kim, Hea-Young Park Choo i Hyun Ae Woo. "Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β". Molecules 27, nr 9 (22.04.2022): 2696. http://dx.doi.org/10.3390/molecules27092696.
Pełny tekst źródłaRamesh, Priyanka, i Shanthi Veerappapillai. "Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer—Fragment Based Drug Design Strategy". Molecules 27, nr 5 (28.02.2022): 1590. http://dx.doi.org/10.3390/molecules27051590.
Pełny tekst źródłaGong, Mengdie, Mingyan Tu, Hongxia Sun, Lu Li, Lili Zhu, Honglin Li, Zhenjiang Zhao i Shiliang Li. "Design, Synthesis, and Structure–Activity Relationship Study of Potent MAPK11 Inhibitors". Molecules 27, nr 1 (29.12.2021): 203. http://dx.doi.org/10.3390/molecules27010203.
Pełny tekst źródłaTian, Tao, Guo-Ying Chen, Hao Zhang i Feng-Qing Yang. "Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose". Molecules 26, nr 15 (30.07.2021): 4638. http://dx.doi.org/10.3390/molecules26154638.
Pełny tekst źródłaFlaumenhaft, Robert, Lynn VerPlank, James R. Dilks, Price S. Blair, Albert Mairuhu, Joseph Negri, Jason Burbank i in. "A Chemical Genetic Analysis of Platelet Activation." Blood 114, nr 22 (20.11.2009): 4009. http://dx.doi.org/10.1182/blood.v114.22.4009.4009.
Pełny tekst źródłaChoi, Ryan, Mowei Zhou, Roger Shek, Jesse W. Wilson, Logan Tillery, Justin K. Craig, Indraneel A. Salukhe i in. "High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity". PLOS ONE 16, nr 4 (22.04.2021): e0250019. http://dx.doi.org/10.1371/journal.pone.0250019.
Pełny tekst źródłaRuseva, Nina, Hristina Sbirkova-Dimitrova, Mariyana Atanasova, Ana Marković, Žaklina Šmelcerović, Andrija Šmelcerović, Adriana Bakalova i Emiliya Cherneva. "Synthesis and DNase I Inhibitory Properties of New Squaramides". Molecules 28, nr 2 (5.01.2023): 538. http://dx.doi.org/10.3390/molecules28020538.
Pełny tekst źródłaHuang, Yuting, Zhaoxing Li, Yuan Ma, Qianqian Wu, Jianping Kong, Lijuan Zhao, Shunxiang Li i Juan Li. "Screening for Active Compounds of Acorus calamus against SARS-CoV-2 Viral Protease and Mechanism Prediction". Pharmaceuticals 17, nr 3 (1.03.2024): 325. http://dx.doi.org/10.3390/ph17030325.
Pełny tekst źródłaSato, Yoshiaki, Ikuo Kashiwakura, Masaru Yamaguchi, Hironori Yoshino, Takeshi Tanaka, Ken Ikeda, Zhengmao Ye, Hirotsugu Komatsu, Takao Matsuzaki i Masato Hosoda. "Discovery of a Novel Small-molecule Interleukin-6 Inhibitor Through Virtual Screening Using Artificial Intelligence". Medicinal Chemistry 18, nr 6 (lipiec 2022): 694–700. http://dx.doi.org/10.2174/1573406418666211116144243.
Pełny tekst źródłaPaiboonrungruang, chorlada. "Abstract 6237: Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia". Cancer Research 83, nr 7_Supplement (4.04.2023): 6237. http://dx.doi.org/10.1158/1538-7445.am2023-6237.
Pełny tekst źródłaJiang, Suping, Sean T. Prigge, Lan Wei, Yu-e. Gao, Thomas H. Hudson, Lucia Gerena, John B. Dame i Dennis E. Kyle. "New Class of Small Nonpeptidyl Compounds BlocksPlasmodium falciparum Development In Vitro by Inhibiting Plasmepsins". Antimicrobial Agents and Chemotherapy 45, nr 9 (1.09.2001): 2577–84. http://dx.doi.org/10.1128/aac.45.9.2577-2584.2001.
Pełny tekst źródłaMoi, Davide, Alessandro Deplano, Andrea Angeli, Gianfranco Balboni, Claudiu T. Supuran i Valentina Onnis. "Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity". Molecules 27, nr 17 (23.08.2022): 5370. http://dx.doi.org/10.3390/molecules27175370.
Pełny tekst źródłaAl-Sanea, Mohammad M. "Synthesis and biological evaluation of small molecule modulators of CDK8/Cyclin C complex with phenylaminoquinoline scaffold". PeerJ 8 (13.03.2020): e8649. http://dx.doi.org/10.7717/peerj.8649.
Pełny tekst źródłaGao, Yinghong, Stephen P. Davies, Martin Augustin, Anna Woodward, Umesh A. Patel, Robert Kovelman i Kevin J. Harvey. "A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery". Biochemical Journal 451, nr 2 (28.03.2013): 313–28. http://dx.doi.org/10.1042/bj20121418.
Pełny tekst źródłaCruz-Migoni, Abimael, Peter Canning, Camilo E. Quevedo, Carole J. R. Bataille, Nicolas Bery, Ami Miller, Angela J. Russell, Simon E. V. Phillips, Stephen B. Carr i Terence H. Rabbitts. "Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds". Proceedings of the National Academy of Sciences 116, nr 7 (25.01.2019): 2545–50. http://dx.doi.org/10.1073/pnas.1811360116.
Pełny tekst źródłaRamshini, Hassan, Reza Tayebee, Alessandra Bigi, Francesco Bemporad, Cristina Cecchi i Fabrizio Chiti. "Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation". International Journal of Molecular Sciences 20, nr 22 (7.11.2019): 5558. http://dx.doi.org/10.3390/ijms20225558.
Pełny tekst źródłaMinhas, Richa, i Yogita Bansal. "iNOS inhibitors: Benzimidazole-coumarin derivatives to combat inflammation". European Journal of Chemistry 13, nr 3 (30.09.2022): 307–18. http://dx.doi.org/10.5155/eurjchem.13.3.307-318.2282.
Pełny tekst źródłaChattopadhyay, Shrikanta, Alison L. Stewart, Siddhartha Mukherjee, Cherrie Huang, Kimberly A. Hartwell, Peter G. Miller, Leigh Carmody i in. "Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma". Blood 120, nr 21 (16.11.2012): 571. http://dx.doi.org/10.1182/blood.v120.21.571.571.
Pełny tekst źródłaAdachi, Ryutaro, Tsuyoshi Ishii, Shinichi Matsumoto, Takuya Satou, Junichi Sakamoto i Tomohiro Kawamoto. "Discovery of Human Intestinal MGAT Inhibitors Using High-Throughput Mass Spectrometry". SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, nr 4 (8.10.2016): 360–65. http://dx.doi.org/10.1177/1087057116673181.
Pełny tekst źródłaMavridis, Evangelos, Eleftherios Bermperoglou, Eleni Pontiki i Dimitra Hadjipavlou-Litina. "5-(4H)-Oxazolones and Their Benzamides as Potential Bioactive Small Molecules". Molecules 25, nr 14 (11.07.2020): 3173. http://dx.doi.org/10.3390/molecules25143173.
Pełny tekst źródłaTrenholme, Katharine, Linda Marek, Sandra Duffy, Gabriele Pradel, Gillian Fisher, Finn K. Hansen, Tina S. Skinner-Adams i in. "Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules". Antimicrobial Agents and Chemotherapy 58, nr 7 (14.04.2014): 3666–78. http://dx.doi.org/10.1128/aac.02721-13.
Pełny tekst źródłaZhao, Hongchuan, Pu Sun, Wei Guo, Yi Wang, Ao Zhang, Linghua Meng i Chunyong Ding. "Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product". Molecules 24, nr 6 (18.03.2019): 1059. http://dx.doi.org/10.3390/molecules24061059.
Pełny tekst źródłaFurbish, Amelia B., Ahmed S. Alford, Pieter Burger, Yuri K. Peterson, Tracy Murray-Stewart, Robert A. Casero i Patrick M. Woster. "Identification and Characterization of Novel Small-Molecule SMOX Inhibitors". Medical Sciences 10, nr 3 (30.08.2022): 47. http://dx.doi.org/10.3390/medsci10030047.
Pełny tekst źródłaVENÄLÄINEN, Jarkko I., Risto O. JUVONEN, J. Arturo GARCIA-HORSMAN, Erik A. A. WALLÉN, Johannes A. M. CHRISTIAANS, Elina M. JARHO, Jukka GYNTHER i Pekka T. MÄNNISTÖ. "Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site". Biochemical Journal 382, nr 3 (7.09.2004): 1003–8. http://dx.doi.org/10.1042/bj20040992.
Pełny tekst źródłaKollár, Levente, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez, Tímea Imre, Ágnes Gömöry i in. "Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads". Cells 10, nr 12 (6.12.2021): 3431. http://dx.doi.org/10.3390/cells10123431.
Pełny tekst źródłaNordio, Giulia, Francesco Piazzola, Giorgio Cozza, Monica Rossetto, Manuela Cervelli, Anna Minarini, Filippo Basagni i in. "From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs". Molecules 28, nr 17 (29.08.2023): 6329. http://dx.doi.org/10.3390/molecules28176329.
Pełny tekst źródłaMoon, Sungho, Seon Yeon Cho, Minhye Kim, Soojeong Beak, Jinhyuk Kim, Yongchan Kim, Sungil Park i in. "Abstract B142: Discovery of novel and potent TEAD inhibitors, orally available small molecules with anti-tumor activity in hippo pathway- dysregulated cancers". Molecular Cancer Therapeutics 22, nr 12_Supplement (1.12.2023): B142. http://dx.doi.org/10.1158/1535-7163.targ-23-b142.
Pełny tekst źródłaRusina, Polina, Erik Gandalipov, Yana Abdusheva, Maria Panova, Alexandra Burdenkova, Vasiliy Chaliy, Maria Brachs i in. "Imidazole-4-N-acetamide Derivatives as a Novel Scaffold for Selective Targeting of Cyclin Dependent Kinases". Cancers 15, nr 15 (25.07.2023): 3766. http://dx.doi.org/10.3390/cancers15153766.
Pełny tekst źródłaFrancini, Cinzia, Francesca Musumeci, Anna Fallacara, Lorenzo Botta, Alessio Molinari, Roberto Artusi, Laura Mennuni, Adriano Angelucci i Silvia Schenone. "Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors". Molecules 23, nr 9 (17.09.2018): 2369. http://dx.doi.org/10.3390/molecules23092369.
Pełny tekst źródłaKulkarni, Amol A., Ayyiliath M. Sajith, Changwen Zhang, Jiukuan Hao i J. Phillip Bowen. "Small molecule prevents inflammation in microglia by targeting the NLRP3 inflammasome". Journal of Immunology 204, nr 1_Supplement (1.05.2020): 160.15. http://dx.doi.org/10.4049/jimmunol.204.supp.160.15.
Pełny tekst źródłaRampogu, Shailima, Ayoung Baek, Chanin Park, Shraddha Parate, Saravanan Parameswaran, Yohan Park, Baji Shaik, Ju Hyun Kim, Seok Ju Park i Keun Woo Lee. "Discovery of Small Molecules that Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies". Cells 8, nr 3 (21.03.2019): 269. http://dx.doi.org/10.3390/cells8030269.
Pełny tekst źródłaGising, Johan, Saman Honarnejad, Maaike Bras, Gemma L. Baillie, Stuart P. McElroy, Philip S. Jones, Angus Morrison, Julia Beveridge, Mathias Hallberg i Mats Larhed. "The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds". International Journal of Molecular Sciences 25, nr 7 (6.04.2024): 4084. http://dx.doi.org/10.3390/ijms25074084.
Pełny tekst źródłaCurreli, Francesca, Shahad Ahmed, Sofia M. B. Victor, Aleksandra Drelich, Siva S. Panda, Andrea Altieri, Alexander V. Kurkin, Chien-Te K. Tseng, Christopher D. Hillyer i Asim K. Debnath. "Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays". Viruses 14, nr 1 (31.12.2021): 69. http://dx.doi.org/10.3390/v14010069.
Pełny tekst źródłaElsawi, Ahmed E., Mai I. Shahin, Hager A. Elbendary, Tarfah Al-Warhi, Fatma E. Hassan i Wagdy M. Eldehna. "1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking". Pharmaceuticals 17, nr 1 (8.01.2024): 81. http://dx.doi.org/10.3390/ph17010081.
Pełny tekst źródłaPorubin, Diana. "Inhibition of in Vitro Nitrosation of Nornicotine". Chemistry Journal of Moldova 2, nr 1 (grudzień 2007): 78–82. http://dx.doi.org/10.19261/cjm.2007.02(1).11.
Pełny tekst źródłaMontanari, Floriane, Anna Cseke, Katrin Wlcek i Gerhard F. Ecker. "Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors". SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, nr 1 (11.07.2016): 86–93. http://dx.doi.org/10.1177/1087057116657513.
Pełny tekst źródłaZhang, Hao, Feng-Qing Yang i Jian-Li Gao. "A Simple and Portable Personal Glucose Meter Method Combined with Molecular Docking for Screening of Lipase Inhibitors". Evidence-Based Complementary and Alternative Medicine 2022 (22.09.2022): 1–9. http://dx.doi.org/10.1155/2022/4430050.
Pełny tekst źródłaAlkhashrom, Sewar, Jintawee Kicuntod, Sigrun Häge, Johannes Schweininger, Yves A. Muller, Peter Lischka, Manfred Marschall i Jutta Eichler. "Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors". Viruses 13, nr 3 (12.03.2021): 471. http://dx.doi.org/10.3390/v13030471.
Pełny tekst źródłaYang, Cheng-Wei, Yung-Ning Yang, Po-Huang Liang, Chi-Min Chen, Wei-Liang Chen, Hwan-You Chang, Yu-Sheng Chao i Shiow-Ju Lee. "Novel Small-Molecule Inhibitors of Transmissible Gastroenteritis Virus". Antimicrobial Agents and Chemotherapy 51, nr 11 (20.08.2007): 3924–31. http://dx.doi.org/10.1128/aac.00408-07.
Pełny tekst źródłaLiargkova, Thalia, Nikolaos Eleftheriadis, Frank Dekker, Efstathia Voulgari, Constantinos Avgoustakis, Marina Sagnou, Barbara Mavroidi, Maria Pelecanou i Dimitra Hadjipavlou-Litina. "Small Multitarget Molecules Incorporating the Enone Moiety". Molecules 24, nr 1 (7.01.2019): 199. http://dx.doi.org/10.3390/molecules24010199.
Pełny tekst źródłaZhang, Yan, i Niefang Yu. "Design, Synthesis and Biological Evaluation: 5-amino-1H-pyrazole-1- carbonyl derivatives as FGFR Inhibitors". Letters in Drug Design & Discovery 17, nr 11 (23.10.2020): 1330–41. http://dx.doi.org/10.2174/1570180817999200608140628.
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