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Artykuły w czasopismach na temat "Short-peptide Derivative"

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Sugiura, Takumi, Takurou Kanada, Daisuke Mori, et al. "Chemical stimulus-responsive supramolecular hydrogel formation and shrinkage of a hydrazone-containing short peptide derivative." Soft Matter 16, no. 4 (2020): 899–906. http://dx.doi.org/10.1039/c9sm01969c.

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Belyaeva, Veronika S., Yulia V. Stepenko, Igor I. Lyubimov, et al. "Non-hematopoietic erythropoietin-derived peptides for atheroprotection and treatment of cardiovascular diseases." Research Results in Pharmacology 6, no. 3 (2020): 75–86. http://dx.doi.org/10.3897/rrpharmacology.6.58891.

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Relevance: Cardiovascular diseases continue to be the leading cause of premature adult death. Lipid profile and atherogenesis: Dislipidaemia leads to subsequent lipid accumulation and migration of immunocompetent cells into the vessel intima. Macrophages accumulate cholesterol forming foam cells – the morphological substrate of atherosclerosis in its initial stage. Inflammation and atherogenesis: Pro-inflammatory factors provoke oxidative stress, vascular wall damage and foam cells formation. Endothelial and mitochondrial dysfunction in the development of atherosclerosis: Endothelial mitochond
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Belyaeva, Veronika S., Yulia V. Stepenko, Igor I. Lyubimov, et al. "Non-hematopoietic erythropoietin-derived peptides for atheroprotection and treatment of cardiovascular diseases." Research Results in Pharmacology 6, no. (3) (2020): 75–86. https://doi.org/10.3897/rrpharmacology.6.58891.

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Relevance: Cardiovascular diseases continue to be the leading cause of premature adult death. Lipid profile and atherogenesis: Dislipidaemia leads to subsequent lipid accumulation and migration of immunocompetent cells into the vessel intima. Macrophages accumulate cholesterol forming foam cells – the morphological substrate of atherosclerosis in its initial stage. Inflammation and atherogenesis: Pro-inflammatory factors provoke oxidative stress, vascular wall damage and foam cells formation. Endothelial and mitochondrial dysfunction in the development of atherosclerosis: Endothelial mitochond
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Mei, Jingjing, Xiaoli Zhang, Meifeng Zhu, Jianing Wang, Ling Wang та Lianyong Wang. "Barium-triggered β-sheet formation and hydrogelation of a short peptide derivative". RSC Adv. 4, № 3 (2014): 1193–96. http://dx.doi.org/10.1039/c3ra45023f.

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Radzishevsky, Inna S., Shahar Rotem, Fadia Zaknoon, Leonid Gaidukov, Arie Dagan, and Amram Mor. "Effects of Acyl versus Aminoacyl Conjugation on the Properties of Antimicrobial Peptides." Antimicrobial Agents and Chemotherapy 49, no. 6 (2005): 2412–20. http://dx.doi.org/10.1128/aac.49.6.2412-2420.2005.

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ABSTRACT To investigate the importance of increased hydrophobicity at the amino end of antimicrobial peptides, a dermaseptin derivative was used as a template for a systematic acylation study. Through a gradual increase of the acyl moiety chain length, hydrophobicity was monitored and further modulated by acyl conversion to aminoacyl. The chain lengths of the acyl derivatives correlated with a gradual increase in the peptide's global hydrophobicity and stabilization of its helical structure. The effect on cytolytic properties, however, fluctuated for different cells. Whereas acylation graduall
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Giannecchini, Simone, Armida Di Fenza, Anna Maria D'Ursi, Donatella Matteucci, Paolo Rovero, and Mauro Bendinelli. "Antiviral Activity and Conformational Features of an Octapeptide Derived from the Membrane-Proximal Ectodomain of the Feline Immunodeficiency Virus Transmembrane Glycoprotein." Journal of Virology 77, no. 6 (2003): 3724–33. http://dx.doi.org/10.1128/jvi.77.6.3724-3733.2003.

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ABSTRACT Feline immunodeficiency virus (FIV) provides a valuable animal model by which criteria for lentivirus control strategies can be tested. Previous studies have shown that a 20-mer synthetic peptide of the membrane-proximal ectodomain of FIV transmembrane glycoprotein, designated peptide 59, potently inhibited the growth of tissue culture-adapted FIV in feline fibroblastoid CrFK cells. In the present report we describe the potential of this peptide to inhibit the replication of primary FIV isolates in lymphoid cells. Because antiviral activity of peptide 59 was found to map to a short se
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Bai, Fengwei, Terrence Town, Deepti Pradhan, et al. "Antiviral Peptides Targeting the West Nile Virus Envelope Protein." Journal of Virology 81, no. 4 (2006): 2047–55. http://dx.doi.org/10.1128/jvi.01840-06.

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ABSTRACT West Nile virus (WNV) can cause fatal murine and human encephalitis. The viral envelope protein interacts with host cells. A murine brain cDNA phage display library was therefore probed with WNV envelope protein, resulting in the identification of several adherent peptides. Of these, peptide 1 prevented WNV infection in vitro with a 50% inhibition concentration of 67 μM and also inhibited infection of a related flavivirus, dengue virus. Peptide 9, a derivative of peptide 1, was a particularly potent inhibitor of WNV in vitro, with a 50% inhibition concentration of 2.6 μM. Moreover, mi
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Falla, T. J., and R. E. Hancock. "Improved activity of a synthetic indolicidin analog." Antimicrobial Agents and Chemotherapy 41, no. 4 (1997): 771–75. http://dx.doi.org/10.1128/aac.41.4.771.

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A novel cationic peptide, CP-11, based on the structure of the bovine neutrophil peptide indolicidin, was designed to increase the number of positively charged residues, maintain the short length (13 amino acids), and enhance the amphipathicity relative to those of indolicidin. CP-11, and especially its carboxymethylated derivative, CP-11C, demonstrated improved activity against gram-negative bacteria and Candida albicans, while it maintained the activity of indolicidin against staphylococci and demonstrated a reduced ability to lyse erythrocytes. In Escherichia coli, CP-11 was better able tha
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Praveen, Praveen, Chao Wang, Thomas N. G. Handley, et al. "A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity." International Journal of Molecular Sciences 24, no. 7 (2023): 6616. http://dx.doi.org/10.3390/ijms24076616.

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Human relaxin-2 (H2 relaxin) is therapeutically very important due to its strong anti-fibrotic, vasodilatory, and cardioprotective effects. Therefore, relaxin’s receptor, relaxin family peptide receptor 1 (RXFP1), is a potential target for the treatment of fibrosis and related disorders, including heart failure. H2 relaxin has a complex two-chain structure (A and B) and three disulfide bridges. Our laboratory has recently developed B7-33 peptide, a single-chain agonist based on the B-chain of H2 relaxin. However, the peptide B7-33 has a short circulation time in vitro in serum (t1/2 = ~6 min).
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Rosa, Elisabetta, Enrico Gallo, Teresa Sibillano, et al. "Incorporation of PEG Diacrylates (PEGDA) Generates Hybrid Fmoc-FF Hydrogel Matrices." Gels 8, no. 12 (2022): 831. http://dx.doi.org/10.3390/gels8120831.

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Generated by a hierarchical and multiscale self-assembling phenomenon, peptide-based hydrogels (HGs) are soft materials useful for a variety of applications. Short and ultra-short peptides are intriguing building blocks for hydrogel fabrication. These matrices can also be obtained by mixing low-molecular-weight peptides with other chemical entities (e.g., polymers, other peptides). The combination of two or more constituents opens the door to the development of hybrid systems with tunable mechanical properties and unexpected biofunctionalities or morphologies. For this scope, the formulation,
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Rozprawy doktorskie na temat "Short-peptide Derivative"

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Lin, Tao. "Self-Assembly of Short Peptide Derivatives." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu161012283431265.

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Conte, Maria Paola. "Directing the self-assembly of short peptide derivatives." Thesis, University of Strathclyde, 2017. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=28511.

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Self-assembly of molecular building blocks has attracted increasing interest as an effective bottom-up approach for the design of functional nanomaterials. Amongst the variety of known molecular building blocks, very short (di- and tri-) peptides and their derivatives are of particular relevance in this context due to their chemical simplicity, low cost and remarkable properties. In this thesis, we first investigate the behaviour of the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) in a predominantly aqueous environment. We demonstrate that thes
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Nanda, Jayanta. "Synthetic Amino Acids and Peptides Based Gels." Thesis, 2019. http://hdl.handle.net/10821/8239.

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The research embodied in the present thesis entitled “SYNTHETIC AMINO ACID AND PEPTIDE BASED GELS” deals with the synthesis, characterization and gelation study of several synthetic self-assembling amino acid and short-peptide derivative and their various applications. Chapter 1 is the general introduction which provides the comprehensive literature survey on low molecular weight supramolecular gels. This chapter highlights structural and morphological features of amino acid and peptide based supramolecular hydrogels and organogels and their different applications. Gel based various nanohybrid
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Basak, Shibaji. "Self Assembling Peptides and Amino Acids based Soft Materials: Functional Gels and Charge Transfer Complexes." Thesis, 2019. http://hdl.handle.net/10821/8244.

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This thesis describes the formation of supramolecular hydrogels and organogels from different synthetic amino acid based amphiphiles and semiconducting organic moiety named naphthalenediimide appended peptide based derivatives. Amino acid and peptide derivatives have been synthesized, purified, characterized and studied in details. Their gelation ability in different aqueous and organic (aromatic/aliphatic) solvents has been studied extensively. These gelator molecules self-associated using various non-covalent interactions including intermolecular hydrogen bonds, electrostatic interactions, -
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Części książek na temat "Short-peptide Derivative"

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Monaco, John J. "Molecular tnechanistns of antigen processing." In Molecular Immunology. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780199633791.003.0005.

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Abstract The mammalian immune system has developed methods for the surveillance of both extracellular and intracellular compartments for 'non-self'. This surveillance is effected by antigen-specific receptors on T lymphocytes, whose natural ligands are short peptides complexed with major histocompatibility complex (MHC) encoded class I or class II molecules. MHC molecules are integral membrane proteins, specifically designed-to bind a diverse set of peptides and to deliver them to the cell surface for recognition by T cells. The structural features of MHC molecules and their peptide binding sp
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