Artykuły w czasopismach na temat „'SBS Independent'”
Kliknij ten link, aby zobaczyć inne rodzaje publikacji na ten temat: 'SBS Independent'.
Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych
Sprawdź 50 najlepszych artykułów w czasopismach naukowych na temat „'SBS Independent'”.
Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.
Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.
Przeglądaj artykuły w czasopismach z różnych dziedzin i twórz odpowiednie bibliografie.
1
Joni, Joni, Jahja Hamdani Widjaja, Maria Natalia i Ivan Junius Salim. "The value of political independent supervisory boards: Evidence from Indonesian dual board setting". ACRN Journal of Finance and Risk Perspectives 10, nr 1 (2021): 128–38. http://dx.doi.org/10.35944/jofrp.2021.10.1.008.
Pełny tekst źródłaStreszczenie:
We investigate whether political independent supervisory boards (political I-SBs) help companies to reduce their corporate risks in the setting of Indonesian two-tier board system. This study is different from other studies in several ways. First, while most prior studies examine the effectiveness of independent boards in one-tier board setting, we use dual board system. This system promotes the strategic role of political I-SBs. Second, we use two measures of corporate risks: operating and market risks. Based on 1,176 firm-year observations for operating risk analysis and 1,254 firm-year observations for market risk analysis, we find that firms with political I-SBs have lower operating and market risks than firms with non- politically connected independent SBs. We also control for endogeneity problem using GMM (Generalized Method of Moments) method, and the results are still consistent.
2
Smaill, Belinda. "Commissioning Difference? The Case of SBS Independent and Documentary". Media International Australia 107, nr 1 (maj 2003): 105–16. http://dx.doi.org/10.1177/1329878x0310700111.
Pełny tekst źródłaStreszczenie:
SBS Independent (SBSI) is the arm of SBS Television responsible for commissioning new work. Since 1994, SBSI has been working in conjunction with other screen funding bodies to commission feature film, short drama, animation and documentary. The charter that dictates the practices of SBS Television also provides guidelines for SBSI, which is consequently required to focus on work that is innovative and concerned with Indigenous issues and cultural diversity. This article focuses on the case of documentary in Australia and the impact of SBSI on a filmmaking community and contemporary documentary culture with particular reference to the Australia by Numbers and Hybrid Life series of half-hour programs. The focus on diversity, and the fact that this is the first Australian television institution to adopt an outsourcing model for almost all production, means that SBSI has formed a unique relationship with independent documentary. Here I examine the specificity and efficacy of this relationship.
3
Gordeev, A. A., V. F. Efimkov, I. G. Zubarev i S. I. Mikhailov. "Phasing of independent laser channels under impact SBS excitation". Quantum Electronics 45, nr 10 (31.10.2015): 899–903. http://dx.doi.org/10.1070/qe2015v045n10abeh015886.
Pełny tekst źródła
4
Gangadharan, G. R., i Erwin Fielt. "Analyzing Requirements and Approaches for Sourcing Software Based Services". International Journal of Applied Logistics 1, nr 2 (kwiecień 2010): 53–63. http://dx.doi.org/10.4018/jal.2010040104.
Pełny tekst źródłaStreszczenie:
Increasingly, software is no longer developed as a single system, but rather as a smart combination of so-called software services. Each of these provides an independent, specific and relatively small piece of functionality, which is typically accessible through the Internet from internal or external service providers. There are no standards or models that describe the sourcing process of these software based services (SBS). The authors identify the sourcing requirements for SBS and associate the key characteristics of SBS (with the sourcing requirements introduced). Furthermore, this paper investigates the sourcing of SBS with the related works in the field of classical procurement, business process outsourcing, and information systems sourcing. Based on the analysis, the authors conclude that the direct adoption of these approaches for SBS is not feasible and new approaches are required for sourcing SBS.
5
Yang, Jianbo, Haifeng Sun, Songlin Wan, Gulsudum Mamtawla, Xuejin Gao, Li Zhang, Yousheng Li, Xinying Wang i Jieshou Li. "Risk Factors for Nephrolithiasis in Adults with Short Bowel Syndrome". Annals of Nutrition and Metabolism 75, nr 1 (2019): 47–54. http://dx.doi.org/10.1159/000502329.
Pełny tekst źródłaStreszczenie:
Introduction: Patients with short bowel syndrome (SBS) commonly develop nephrolithiasis. However, the risk factors for nephrolithiasis in patients with SBS remain unclarified. The present study aimed to identify the risk factors for nephrolithiasis in adults with SBS. Methods: All eligible adults diagnosed with SBS and admitted to a tertiary referral center from December 2008 to 2018 were retrospectively identified from a prospectively maintained database. Patients’ demographic and clinical characteristics were analyzed using univariate and multivariate analyses to identify the risk factors for nephrolithiasis. Results: Of 231 adults with SBS, 42 (18.2%) developed nephrolithiasis. The mean age was 46.4 ± 17.8 years, the mean body mass index was 18.2 ± 3.8 kg/m2, and median duration of SBS was 11 months (range 2–324 months). Multivariate binary logistic regression analysis revealed that the independent risk factors for nephrolithiasis in adults with SBS were jejuno-ileal anastomosis and colon-in-continuity (OR 4.335; 95% CI 1.175–16.002; p = 0.028), prolonged duration of SBS (OR 1.008; 95% CI 1.002–1.014; p = 0.010), and increased serum creatinine concentration (OR 1.005; 95% CI 1.001–1.009; p = 0.012). Conclusions: Nephrolithiasis is common in adults with SBS. As nephrolithiasis can have adverse clinical consequences, patients with SBS should be closely monitored, and prophylactic interventions should be considered.
6
Kang, Yang, Dunhong Zhou, Qiang Wu, Fuyan Duan, Rufang Yao i Kun Cai. "Fully Atomistic Molecular Dynamics Computation of Physico-Mechanical Properties of PB, PS, and SBS". Nanomaterials 9, nr 8 (29.07.2019): 1088. http://dx.doi.org/10.3390/nano9081088.
Pełny tekst źródłaStreszczenie:
The physical properties—including density, glass transition temperature (Tg), and tensile properties—of polybutadiene (PB), polystyrene (PS) and poly (styrene-butadiene-styrene: SBS) block copolymer were predicted by using atomistic molecular dynamics (MD) simulation. At 100 K, for PB and SBS under uniaxial tension with strain rate ε ˙ = 1010 s−1 and 109 s−1, their stress–strain curves had four features, i.e., elastic, yield, softening, and strain hardening. At 300 K, the tensile curves of the three polymers with strain rates between 108 s−1 and 1010 s−1 exhibited strain hardening following elastic regime. The values of Young’s moduli of the copolymers were independent of strain rate. The plastic modulus of PS was independent of strain rate, but the Young’s moduli of PB and SBS depended on strain rate under the same conditions. After extrapolating the Young’s moduli of PB and SBS at strain rates of 0.01–1 s−1 by the linearized Eyring-like model, the predicted results by MD simulations were in accordance well with experimental results, which demonstrate that MD results are feasible for design of new materials.
7
Liu, Rui-Qiang, Xiao-Xiong Wang, Jie Fu, Qian-Qian Zhang, Wei-Zhi Song, Yuan Xu, You-Qiang Chen, Seeram Ramakrishna i Yun-Ze Long. "Preparation of Nanofibrous PVDF Membrane by Solution Blow Spinning for Mechanical Energy Harvesting". Nanomaterials 9, nr 8 (30.07.2019): 1090. http://dx.doi.org/10.3390/nano9081090.
Pełny tekst źródłaStreszczenie:
Self-powered nanogenerators composed of poly(vinylidene fluoride) (PVDF) have received much attention. Solution blow spinning (SBS) is a neoteric process for preparing nanofiber mats with high efficiency and safely, and SBS is a mature fiber-forming technology that offers many advantages over conventional electrospinning methods. Herein, we adopted the SBS method to prepare independent PVDF nanofiber membranes (NFMs), and successfully employed them as nanogenerators. Finally, we tested the change in the output current caused by mechanical compression and stretching, and studied its durability and robustness by charging the capacitor, which can drive tiny electronic devices. The results show that the PVDF nanogenerators by using this SBS equipment can not only be used in wearable electronic textiles, but are also suitable for potential applications in micro-energy harvesting equipment.
8
Martins, Luís Roberto Marcondes, Mario Vedovello Filho, Suzy H. A. Martins, Heloísa C. Valdrighi, Silvia Amélia S. Vedovello, Mayury Kuramae, Adriana Simoni Lucato i Eloisa Marcantonio Boeck. "Evaluation of Bonded Orthodontics Brackets Using Different Adhesive Systems after a Cariogenic Challenge". Journal of Contemporary Dental Practice 11, nr 1 (styczeń 2010): 41–48. http://dx.doi.org/10.5005/jcdp-11-1-41.
Pełny tekst źródłaStreszczenie:
Abstract Aim The aims of this study were to evaluate the prevention of enamel demineralization and the shear bond strength (SBS) of orthodontic brackets bonded with fluoride and no fluoride conventional and selfetching adhesives and to analyze the characteristics of enamel near the bond area using a polarized light microscope (PLM) following demineralization and remineralization cycling (Des Re). Methods and Materials Fifty bovine incisors were selected and divided into five groups according to the adhesive system used during the bonding process: G1, Transbond™ XT Adhesive; G2, Single Bond 2 Adhesive; G3, Optibond Solo Plus; G4, Clearfil SE Bond; and G5, Clearfil Protect Bond. Transbond™ XT was used to fix the brackets to the teeth in all groups. After bonding, the groups were separated into cycling and control subgroups. The specimens were submitted to SBS testing and evaluated under a PLM. The results were submitted to ANOVA and Tukey's post hoc tests (p<.05). Results There were no significant differences for SBS after Des-Re cycling. The Clearfil Protect Bond showed the SBS to be statistically lower than the other adhesives used for the control groups. After a cariogenic challenge, the Single Bond adhesive showed an SBS significantly lower than Transbond XT. The Des-Re cycling increased the enamel demineralization induced after the cariogenic challenge. Conclusions The cariogenic challenge did not reduce the SBS. Optibond Solo Plus and Transbond™ XT adhesives presented the highest SBS while Clearfil Protect Bond had the lowest. The PLM showed that the cariogenic challenge increased the enamel demineralization for all adhesives evaluated, independent of the presence of fluoride. Clinical Significance An alternative material with the ability to prevent enamel demineralization should be used in orthodontic patients due to the higher accumulation of plaque around orthodontic brackets. Citation Filho MV, Martins SHA, Valdrighi HC, Vedovello SAS, Kuramae M, Lucato AS, Boeck EM, Martins LRM. Evaluation of Bonded Orthodontics Brackets Using Different Adhesive Systems after a Cariogenic Challenge. J Contemp Dent Pract [Internet]. 2010 Jan; 11(1):041-048. Available from: http://www.thejcdp.com/journal/ view/volume11-issue1-filho.
9
Hikmat, Yudi Prana, Ismail Wellid, Kasni Sumeru, Salma Dzakiyah Az-zahro i Mohamad Firdaus bin Sukri. "Relationship Between Indoor Air Quality and Sick Building Syndrome in Post Office Building in Bandung". Current Journal: International Journal Applied Technology Research 2, nr 2 (1.10.2021): 136–45. http://dx.doi.org/10.35313/ijatr.v2i2.53.
Pełny tekst źródłaStreszczenie:
Sick building syndrome (SBS) is a collection of symptoms experienced by buildings occupants such as headaches, mucous, membrane irritation, respiratory problems and fatigue. A building is claimed to have SBS if more than 20% of building occupants experience symptoms. Poor indoor air quality contributes to SBS in the building. This study aims to investigate the correlation between indoor air quality and SBS symptoms in 1st and 2nd floors of the Post office building in Bandung. The study used quantitative methods with a cross sectional study design. Data collection was carried out using particle counter, thermometer, lux meter and anemometer to measure the indoor air quality, while the questionnaire utilized random sampling technique with 119 respondents. The results of the primary data were compared with the air quality standard from Minister of Health No. 1077, 2021. The results of the Statically Compare Means and Independent T-test showed that the p-values of the temperature on the 1st floor and 2nd floors were 0.437 and 0.000, respectively. Meanwhile the p-values of PM10 and PM2.5 on the 1st and 2nd floors were 0.005 and 0.290 and 0.004 and 0.364, respectively, and the p-values of the lighting on the 1st and 2nd floors were 0.002 and 0.015. It indicates that there is a significant relationship between concentrations of PM10 and PM2.5 on the 1st floor with SBS symptoms and the temperature and humidity on the 2nd with SBS symptoms. Since 29 peoples (24% of the building’s occupants) experienced SBS, the building was considered to have a significant potential to cause SBS to its occupant.
10
MV, Gentilini, Doeyo M, Ortega M, Illidge Perez L, Rumbo C, Arriola Benitez PC, Crivelli A, Rumbo M, Solar H i Gondolesi GE. "Successful pregnancy in a patient with short bowel syndrome after surgical rehabilitation and sGLP-2 treatment: novel report on endogenous GLP-2 levels at delivery and during breastfeeding". Therapeutic Advances in Gastroenterology 15 (styczeń 2022): 175628482211297. http://dx.doi.org/10.1177/17562848221129787.
Pełny tekst źródłaStreszczenie:
Pregnant patients with short bowel syndrome (SBS) and chronic intestinal failure (CIF) can successfully reach to term their pregnancies while on parenteral nutrition (PN) but with high rates of complications. The combination of rehabilitation surgery, combined with the use of novel treatment with enterohormones, especially semisynthetic glucagon-like peptide 2 (sGLP-2), has increased the chances to achieve intestinal sufficiency. Here, we report the case of a 33-year-old female with SBS/CIF (anatomy type 2), weaned off PN using sGLP-2 for 3.7 years, discontinued when she became pregnant. She was able to carry the pregnancy to term without any additional PN support. Considering that, we queried if the endogenous GLP-2 (eGLP-2) levels in this SBS patient, during the pregnancy and breastfeeding period, could be like those presented in healthy pregnant women and in non-pregnant SBS patients. Also, we inquired if there was any passage or increase in the plasmatic eGLP-2 from the fetus to the mother. Thus, we determined eGLP-2 levels in paired neonatal (cord blood) and maternal plasma samples from the SBS pregnant patient ( n = 1), healthy pregnant women (controls, n = 2), and non-pregnant SBS patients ( n = 12). The results indicated that the SBS pregnant patient showed higher eGLP-2 levels than non-SBS pregnant patients and healthy pregnant women along all the period studied. Furthermore, we found that the maternal sample had higher eGLP-2 levels than the neonatal sample, suggesting that fetal contribution to maternal eGLP2 levels would be minor. In conclusion, this study not only reports for the first time a case of a patient with SBS that was able to achieve intestinal adaptation after combining the use of autologous reconstructive surgery and sGLP-2, but also enlightens the possibility of carrying out an uneventful pregnancy and lactation without any nutritional support and remaining independent of sGLP-2.
11
Alhowaish, Latifa, Fouad Salama, Mohammed Al-Harbi i Mohamad Abumoatti. "Shear Bond Strength of a Resin Composite to Six Pulp Capping Materials Used in Primary Teeth". Journal of Clinical Pediatric Dentistry 44, nr 4 (1.08.2020): 234–39. http://dx.doi.org/10.17796/1053-4625-44.4.4.
Pełny tekst źródłaStreszczenie:
Aim: The purpose of this in vitro study was to assess the shear bond strength (SBS) and bond failure types of a resin-composite to six pulp-capping materials used in primary teeth. Study design: Eight-disc specimens from each pulp-capping material (6 groups) to bond to Filtek™ Z350 XT Flowable using a standard PVC tube (2×2mm). All groups were prepared according to the instruction of the manufacturer. The SBS was measured with a crosshead speed of 0.5 mm/min using a universal testing machine. Failure mode evaluation was completed using Digital Microscope by two independent examiners. Results: Urbical LC® showed the highest SBS (Mean±SD) followed by ProRoot® MTA and TheraCal LC® (35.422±2.910, 22.114±2.515, and 21.175±1.983) respectively. ANOVA showed significant differences between all groups (P=0.0001). Urbical LC® and Photac™ Fil QuickAplicap™ were statistically significant different from all other pulp-capping materials groups. ProRoot® MTA was statistically significant different than Biodentine® (P=0.0001) and Photac™ Fil (P=0.0001). The total number of bond failure was recorded for cohesive B failure/cohesive in the pulp-capping material (14) and adhesive failure (14). Conclusion: Most of the tested pulp-capping materials bonded to Filtek™ Z350 XT demonstrated clinically acceptable and high SBS. Urbical LC showed the highest SBS while Biodentine® showed the lowest SBS.
12
Xing, Chen, Changjian Ke, Ke Zhang, Zhen Guo, Yibo Zhong i Deming Liu. "Polarization- and wavelength-independent SBS-based filters for high resolution optical spectrum measurement". Optics Express 25, nr 18 (21.08.2017): 20969. http://dx.doi.org/10.1364/oe.25.020969.
Pełny tekst źródła
13
Aljdaimi, Abtesam, Hugh Devlin i Mark Dickinson. "Effect of the Er: YAG laser on the shear bond strength of conventional glass ionomer and BiodentineTM to dentine". European Journal of Dentistry 12, nr 03 (lipiec 2018): 380–85. http://dx.doi.org/10.4103/ejd.ejd_410_17.
Pełny tekst źródłaStreszczenie:
ABSTRACTObjectives: The purpose of this study was to determine if Er: YAG laser etching improves the shear bond strength (SBS) of Biodentin™ and GC Fuji IX® to dentine. Materials and Methods: Forty human dentine specimens were standardized and embedded in stone. The specimens were randomized into four groups (n = 10). Twenty samples were treated with the Er: YAG laser radiation and 10 of these restored with GC Fuji IX® and 10 with Biodentine™. The remaining 20 specimens acted as controls (no laser treatment); 10 were restored with GC Fuji IX® and 10 with Biodentin™. All samples were then stored in an incubator at 37.5°C and 100% humidity for 7 days. The SBS was determined using a Zwick universal testing machine. A two-way analysis of variance test was used to evaluate the statistical difference in SBS between the groups. An independent sample t-test was used to determine the statistical significance of differences between control and lased groups within the same material. Results: A highly statistically significant difference in SBS was found with the laser treatment (P = 0.0001) and material (i.e., Biodentin™ or Fuji IX® (P = 0.0001). The GC Fuji IX® group recorded the highest mean SBS required to dislodge the material from the laser-treated dentine surface (1.77 ± 0.22 Mega-Pascal [MPa]). The mean SBS of Biodentin™ to dentine following the laser radiation (1.12 ± 0.16 MPa) was significantly greater compared to the nonlased dentine (0.53 ± 0.09). Pearson Chi-square test indicated a nonsignificant relation between shear strength and mode of failure (P = 0.467). Conclusion: Laser etching of the dentine surfaces yielded a significant increase in the bond strength for both GC Fuji IX® and Biodentin™. The SBS of Biodentin™ to dentine is greater than with conventional glass ionomer (Fuji IX®).
14
Kang, Hyeon, Min-Kyung Ji, Hoon-Sung Cho, Sang-Won Park, Kwi-Dug Yun, Chan Park i Hyun-Pil Lim. "Effect of Plasma Surface Treatment on Shear Bond Strength with Denture Base Resin in Co–Cr Alloy, Ti–6Al–4V Alloy, and CP–Ti Alloy". Journal of Nanoscience and Nanotechnology 20, nr 9 (1.09.2020): 5771–74. http://dx.doi.org/10.1166/jnn.2020.17630.
Pełny tekst źródłaStreszczenie:
The purpose of this study was to examine the effect of plasma treatment by treating the surface of Co–Cr alloy, Ti–6Al–4V alloy, and CP–Ti alloy as a material for denture metal frameworks with non-thermal atmospheric pressure plasma (NTAPP) and measuring their shear bond strength (SBS) with a heat-cured resin. 20 specimens were prepared for each of Co–Cr, Ti–6Al–4V, and CP–Ti alloys. Each metal alloy group was divided into the following subgroups depending on NTAPP treatment: C (Co–Cr alloy without plasma), T (CP–Ti without plasma), A (Ti–6Al–4V alloy without plasma), CP (Co–Cr alloy with plasma), TP (CP–Ti with plasma) and AP (Ti–6Al–4V alloy with plasma). Specimens were treated with a metal conditioner and bonded to a denture base resin. SBS was measured using a universal testing machine. All data obtained were statistically analyzed using two-way analysis of variance (ANOVA), Tukey’s honestly significant difference (HSD) test, and independent t-test. The mean values (SD) of SBS (MPa) were: 10.31 (1.19) for C group; 12.43 (0.98) for T group; 13.75 (2.02) for A group; 13.53 (1.61) for CP group; 16.87 (1.55) for TP group; 17.46 (1.65) for AP group. The SBS of the AP group was the highest while that of the C group was the lowest. SBS of specimen treated with NTAPP was significantly increased regardless of metal alloy types (p < 0.001). Within the limitations of this study, NTAPP can increases the SBS of Co–Cr alloy, CP–Ti alloy, and Ti–6Al–4V alloy with a denture base resin.
15
Hatf, Ahmed D., i Mustafa M. AL-Khatieeb. "Effect of ageing media on shear bond strength of metal orthodontic brackets bonded with different adhesive systems (A comparative in-vitro study)". Journal of Baghdad College of Dentistry 32, nr 4 (15.12.2020): 5–11. http://dx.doi.org/10.26477/jbcd.v32i4.2912.
Pełny tekst źródłaStreszczenie:
Background: The aim of this study was to evaluate the shear bond strength (SBS) and adhesive remnant index (ARI) of different orthodontic adhesive systems after exposure to aging media (water storage and acid challenge). Materials and methods: Eighty human upper premolar teeth were extracted for orthodontic purposes and randomly divided into two groups (40 teeth each): the first group in which the bonded teeth were stored in distilled water for 30 days at 37°C, and the second group in which the bonded teeth were subjected to acid challenge. Each group was further subdivided into four subgroups (10 teeth each) according to the type of adhesive system that would be bonded to metal brackets: either non-fluoride releasing adhesive (NFRA), fluoride releasing adhesive (FRA), Fluoride releasing bond with self-etching primer (FRBSP), or powder and liquid orthodontic fluoride releasing adhesive (PLFRA). After 30 days of water storage and acid challenge ageing procedures, the SBS was determined using Instron testing machine with a crosshead speed of 1 mm/min. The ARI was assessed using a stereomicroscope with 10 X magnification. Result: The SBS testing revealed significant differences (p< 0.05) among the four tested adhesive systems in water storage and acid challenge groups using ANOVA F-test. In both groups, the NFRA subgroup exhibited the highest mean SBS value, followed by FRASP, then FRA subgroups, while the PLFRA subgroup had the lowest value of mean SBS. The independent t-test showed non-significant differences in mean SBS values between water storage and acid challenge groups. In respect to the ARI analysis, the Chi-square test showed significant differences among the tested adhesive systems. Conclusion: The shear bond strength of the fluoride releasing adhesive system was less than that of the non-fluoride releasing adhesive system, but still above the clinically acceptable range.
16
Kocakaya, Serhat, i Ferit Kocakaya. "A Structural Equation Modeling on Factors of How Experienced Teachers Affect the Students’ Science and Mathematics Achievements". Education Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/490371.
Pełny tekst źródłaStreszczenie:
The main purpose of this study was to propose a model for how elementary school students’ science and mathematics achievements in their schools and in Level Determination Exam (SBS) depend on the number of teachers and expert teachers in their schools. The sample of the study was 5672 elementary students for the purpose of the study, the number of teachers and expert teachers who worked in sample schools has been defined as independent variables, and students’ science and mathematics achievements in their schools and in SBS exam have been defined as dependent variables. The data obtained from school administrations were analyzed using structural equation modeling to analyze relations among students’ science and mathematics grades in their schools and science and mathematics achievements in SBS exam and the number of teachers and expert teachers in their school. As a result of the analysis, it has been observed that established model has acceptable fit indices and an increasing number of teachers and expert teachers have positive effects on students' science and mathematics achievements.
17
Coletta, Riccardo, Bashar Aldeiri i Antonino Morabito. "Institutional Experience with Spiral Intestinal Lengthening and Tailoring". European Journal of Pediatric Surgery 29, nr 05 (19.06.2018): 412–16. http://dx.doi.org/10.1055/s-0038-1660850.
Pełny tekst źródłaStreszczenie:
Aim The aim of this study was to report our initial experience using spiral intestinal lengthening and tailoring (SILT) technique in selected cases of short bowel syndrome (SBS). Materials and Methods We analyzed all cases of SBS underwent SILT in our unit since the introduction of the procedure in 2012. We retrospectively analyzed patients' demographics, pre- and postprocedure bowel length, surgical complications, and postoperative parenteral nutrition (PN) requirements. Data were compared using independent samples, Mann–Whitney's U-test. Results Five children with SBS underwent SILT between 2012 and 2017. Median age at procedure was 8.3 months (4.5–16). Preoperative small bowel length measured a median of 22 cm (17.5–50) with a median diameter of 4 cm (3.5–4.6). SILT allowed a median increase in length of 56% (10–15 cm; p = 0.03) and tailoring of the dilated segment providing a reduction in diameter of 50% (4.3–2.1 cm; p = 0.01). No major complications related to SILT were encountered and none of the children required further surgical intervention following a median follow-up of 26 months (14.5–41). Interestingly, we observed a significant reduction of PN requirement at 6 months (p = 0.008) associated with liver function preservation during the follow-up period. Conclusion In our experience, SILT is a promising adjunct in the surgical management of SBS. It can be used to tailor and lengthen mildly dilated segments of the bowel where other procedures are technically challenging, with a view to reduce the risk of intestinal failure associated liver disease and thereby improving chances for quality survival. Further studies are needed to investigate long-term outcomes of SILT in pediatric SBS.
18
Qanber, Lubna M., i Thekra I. Hamad. "Effect of plasma treatment on the bond of soft denture liner to conventional and high impact acrylic denture materials". Journal of Baghdad College of Dentistry 33, nr 3 (15.09.2021): 9–17. http://dx.doi.org/10.26477/jbcd.v33i3.2948.
Pełny tekst źródłaStreszczenie:
Background: The main drawback of soft lining materials was that they debonded from the denture base after a certain period of usage. Therefore, the purpose of this research was to determine the impact of oxygen and argon plasma treatment on the shear bonding strength of soft liners to two different kinds of denture base materials: conventional acrylic resin and high impact acrylic resin. Materials and Methods: Heat cure conventional and high impact acrylic blocks (40 for each group) were prepared. A soft liner connected the final test specimen of two blocks of each acrylic material. Shear bond strength (SBS) was assessed using universal testing machine. Additional blocks were also prepared for analyzing Vickers microhardness, contact angle, FTIR and AFM. The results were statistically analyzed using paired-sample T-test and independent-samples T-test (α=0.05). Results: The results showed a highly significant increase in SBS following plasma treatment with the highest mean value observed in plasma treated high impact acrylic specimen. Along with a significant rise in wettability, while microhardness was preserved. Conclusion: In conclusion, oxygen and argon plasma treatment was significantly effective in enhancing the SBS between soft liner and acrylic materials.
19
do Nascimento Simões, Braga Aluska, Valdeci Bosco dos Santos, Gomes Déborah dos Santos, Simões Veruska do Nascimento, Neves Gelmires de Araújo i Romualdo Rodrigues Menezes. "Evaluation of Processing Parameters in the Synthesis of Silica Nanofibers Doped with Silver by the Solution Blow Spinning Method". Materials Science Forum 958 (czerwiec 2019): 135–40. http://dx.doi.org/10.4028/www.scientific.net/msf.958.135.
Pełny tekst źródłaStreszczenie:
The ceramic fibers can be obtained from different techniques. Due to the technological development, searches are performed to improve the existing fibers. Thus, recent studies have enabled the development of an unprecedented synthesis route for the production of nanofibers, the Solution Blow Spinning (SBS). In this context, the present work proposes to develop silica nanofibers doped with silver by the SBS method, evaluating parameters such as: silver content and acidification of solutions. The fibers were characterized by X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). The results of XRD showed that the samples with 4% silver that were not acidified showed the most defined and intense characteristic peaks. The SEM showed the formation of fibers with diameters in the nanometer range independent of acidification or not of the solutions, with reduction of the agglomerates in the samples with 2% silver.
20
Asiri, Abdulmajeed Ali, Rawaiz Khan, Sultan Saeed Alzahrani, Sajjad Haider, Salah Ud-Din Khan, Essa Ali Mousa Asiri, Maha Fayez Alamri, Ashfaq Ahmad i Muhammad Mubushar. "Comparative Analysis of the Shear Bond Strength of Flowable Self-Adhering Resin-Composites Adhesive to Dentin with a Conventional Adhesive". Coatings 11, nr 3 (25.02.2021): 273. http://dx.doi.org/10.3390/coatings11030273.
Pełny tekst źródłaStreszczenie:
This study aimed to measure and compare the shear bond strength (SBS) of a self-adhering flowable resin composite to dentin with a conventional flowable composite, and evaluate the various modes of failure. Thirty human premolar teeth (n = 30) were randomly allocated to two groups (Group I: Vertise™ Flow; Group II: Filtek Ultimate + Single Bond Universal) of 15 specimens each, and SBS was measured for specimens from each group by applying a shear load using a universal testing machine (UTM). Modes of failure were observed with an optical microscope. An independent-samples T-test was performed to test Levene’s assumption of homogeneity of variance across both groups, with the critical value set at 0.05. The results revealed, that the self-adhering flowable composite (Group I: Vertise™ Flow) resulted in a lower shear bond strength compared with the conventional adhesive system composite (Group II: Filtek Ultimate + Single Bond Universal). Moreover, group I predominantly exhibited non-cohesive failure, which reflects poor bonding to dentin. On the other hand, Group II showed mixed failure for most of the samples, which demonstrated strong adhesive bonding. Therefore, it could be concluded that the self-adhering flowable resin composite (Group I) results in lower SBS to dentin compared with a conventional adhesive system.
21
Xavier, Maria Teresa, Ana Luísa Costa, Francisco José Caramelo, Paulo Jorge Palma i João Carlos Ramos. "Evaluation of the Interfaces between Restorative and Regenerative Biomaterials Used in Vital Pulp Therapy". Materials 14, nr 17 (3.09.2021): 5055. http://dx.doi.org/10.3390/ma14175055.
Pełny tekst źródłaStreszczenie:
Background: Calcium-silicate-based cements (CSC) have gained an increasing scientific and clinical relevance, enabling more conservative approaches, namely pulp preservation and regeneration therapies. This research aims to study the influence of four clinical variables on the interfaces between CSC and composite adhesive restoration, concerning shear bond strength (SBS) and ultra-morphological patterns. Methods: SBS tests were performed in 320 specimens divided in 16 groups (n = 20) according to: two CSC (NuSmile® NeoMTA, BiodentineTM); two adhesive systems (ClearfilTM SE Bond 2 (CSEB2), ClearfilTM Universal Bond Quick (CUBQ)); optional application of an additional hydrophobic bonding layer (HBL); two restoration times (immediate, seven days). Scanning electron microscopy (SEM) was performed to conduct the ultra-morphology interface analysis in 32 deciduous molars prepared and randomly allocated into the 16 groups. Results: Globally, SBS tests showed higher bond strength of CUBQ compared to CSEB2 (p < 0.001), as with an additional HBL application (p = 0.014) and delayed restoration (p < 0.001). SEM showed the interpenetration between adhesive systems and CSC forming a hybrid layer, whose depth and thickness depended on the restoration time and adhesive strategy. Conclusions: The independent clinical variables adhesive system, application of an additional HBL and restoration time affected the bond performance and ultra-morphological interface between composite adhesive restoration and CSC.
22
Akarsu, Serdar, Suleyman Kutalmış Buyuk i Ahmet Serkan Kucukekenci. "Effects of adhesive systems at different temperatures on the shear bond strength of orthodontic brackets". Journal of Dental Research, Dental Clinics, Dental Prospects 13, nr 2 (14.08.2019): 103–8. http://dx.doi.org/10.15171/joddd.2019.016.
Pełny tekst źródłaStreszczenie:
Background. The temperature might affect the physical and mechanical properties of adhesive materials by reducing the polymerization rate. The present study aimed to evaluate the effect of temperature on the shear bond strength of metallic orthodontic brackets using various adhesive resin systems. Methods. Extracted human premolar teeth were randomly assigned to 8 groups (n=10) for bonding with the two available orthodontics adhesive systems (Transbond XT and NeoBond) at different temperatures: refrigeration temperature (4°C), room temperature (20°C), human body temperature (36°C) and high temperature (55°C). The shear bond strength (SBS) test was performed using a universal testing machine at a crosshead speed of 0.5 mm/min. The adhesive remnant index (ARI) was assigned to the fractured orthodontic brackets. Data were analyzed with one-way ANOVA, post hoc Tukey tests and independent t-test. Results. Transbond XT exhibited higher SBS values compared to Neobond at all the tested temperatures; however, a statistically significant difference was not observed (P>0.05). The SBS results were minimum at 4°C and maximum at 36°C in both the adhesive groups (P<0.05). Conclusion. Pre-heating orthodontic adhesives up to the body temperature prior to bonding the brackets in orthodontic treatment increased the bond strength of orthodontic brackets.
23
Anggraeni, Anita, i Luciana Spica Almilia. "Model Belief Adjustment dalam Pengambilan Keputusan Investasi Berdasarkan Informasi Nonakuntansi". Jurnal Ekonomi dan Bisnis 20, nr 1 (17.07.2017): 149. http://dx.doi.org/10.24914/jeb.v20i1.923.
Pełny tekst źródłaStreszczenie:
<p><em>The purpose of this study is to examine is there any difference on investment decision making among participant that received good news information followed by bad news compared with participant that received bad news information followed by good news on the SbS and EoS information disclosure pattern, also long and short information series. The experiment design in this study is 2x2x2 mix design subject, which is the information disclosure pattern (step by Step and End of Sequence), information order (good news followed by bad news), and information series (long and short infomation series). The Independent Sample t-test used to examined the research hypothesis. The amount of participant involved on this study are 96 college students in STIE Perbanas Surabaya in Accountant and Management major. The result show that there were difference on investment decision making among participant that received good news information followed by bad news compared with participant that received bad news information followed by good news on the SbS information disclosure pattern and long information series and also occurs recency effect.</em></p><p align="center"><strong>Abstrak <br /></strong></p><p>Tujuan penelitian ini adalah menguji perbedaan keputusan investasi antara partisipan yang menerima informasi good news diikuti bad news dibandingkan dengan partisipan yang menerima informasi bad news diikuti good news, baik pada pola penyajian SbS maupun EoS dan seri informasi panjang dan pendek. Penelitian ini menggunakan metoda eksperimen 2x2x2 mix design, yaitu pola penyajian (step by step dan end of sequence) dan urutan informasi (good news diikuti bad news dan bad news diikuti good news) dan seri informasi (informasi panjang dan informasi pendek). Independent Sample t test digunakan untuk menguji hipotesis penelitian. Jumlah partisipan dalam penelitian ini adalah 96 mahasiswa Akuntansi dan Manajemen STIE Perbanas Surabaya. Hasil penelitian menunjukkan bahwa terdapat perbedaan dalam pengambilan keputusan investasi dan terjadi recency effect bagi partisipan yang menerima good news diikuti bad news dibandingkan dengan partisipan yang menerima informasi bad news diikuti bad news pada pola penyajian SbS dan seri informasi panjang.<em><br /></em></p>
24
Abdullah, Huda Abbas, Zahraa Abdulaali Al-Ibraheemi, Zanbaq Azeez Hanoon i Julfikar Haider. "Evaluation of Shear Bond Strength of Resin-Based Composites to Biodentine with Three Types of Seventh-Generation Bonding Agents: An In Vitro Study". International Journal of Dentistry 2022 (30.07.2022): 1–9. http://dx.doi.org/10.1155/2022/2830299.
Pełny tekst źródłaStreszczenie:
Background and Aim. Biodentine refers to a bioactive material commonly applied for dental restoration in clinical practice, but poor adhesion of the Biodentine to the restorative materials could affect the quality and long-term integrity of the final restoration. The study aimed to assess shear bond strength (SBS) of two resin-based composites to Biodentine using three commercially available 7th generation bonding agents. Methods. Forty-eight acrylic blocks having central holes with a nominal diameter of 4 mm and a depth of 2 mm were prepared. The holes of the acrylic blocks were filled with Biodentine, which was prepared following the guidelines provided by the manufacturer. Then, the specimens were divided into six groups (n = 8). Groups 1, 2, and 3, Tetric N-Ceram composite bonded to Biodentine with Tetric N-bond, Xeno V+, Bond Force bond, respectively. Group 4, 5, and 6, Filtek Z350 bonded to Biodentine with the same three adhesives. The specimens were placed in distilled water for 24 hours and tested for the SBS in a universal testing machine at a crosshead speed of 1 mm/min. The test data were listed in a table and independent samples t-test and analysis of variance (ANOVA) were conducted as a part of the statistical analysis. Results. The Tetric N bonding agent achieved the highest SBS followed by Bond Force, and Xeno V and highly significant difference was found. On the other hand, an overall increase in the SBS values of the Tetric N-Ceram resin was noticed in comparison with the Filtek Z350 and the differences was statistically significant. Although the specimens failed in adhesive, cohesive and mixed fracture modes but the cohesive was found to be the dominant failure mode in all groups. Conclusion. Among the tested bonding agents and resin composites, the Tetric N-Ceram composite bonded by Tetric N-bond self-etch adhesive with the Biodentine showed the highest SBS compared to the other combinations.
25
Satriani, Arbaiyah. "Framing Analysis of News Article about Clashes between Police and Terrorist Prisoners in Indonesia Publishing by ABC.net.au and SBS.com". Mediator: Jurnal Komunikasi 11, nr 2 (15.12.2018): 248–55. http://dx.doi.org/10.29313/mediator.v11i2.3947.
Pełny tekst źródłaStreszczenie:
In 10 May 2018, six policemen had been killed in clashes between Indonesian police and prisoners in the jail in the Mobile Police Brigade (Brimob) headquarters in Depok, West Java. It was located in outskirts of Jakarta. The incident had attracted people’s attention from all around the world. One of the reasons was because it taken place in the headquarters of the police. It can be said as a dramatic tragedy. Another reason that it magnetized public’s awareness was because it involved so call terrorist prisoners. Two of online media that distributed news article about it in Australia were ABC and SBS new sites. Both of them are independent media and have difference focus of publication in their media. The aim of this paper is to explore how the two media, ABC and SBS new sites, frame the event in their publication. It is interesting to observe how the media in Australia which has special attention to the issues of Indonesia published the news article related to a hot topic in Indonesia
26
Sa’ada, Maiada Mohammad Ahmad, Nagwa Mohammed Ali Khattab i Maha Ishaq Amer. "Effect of Silver Diamine Fluoride Pretreatment on Shear Bond Strength of Resin Modified Glass Ionomer Cement to Primary Dentin". Open Access Macedonian Journal of Medical Sciences 9, nr D (20.09.2021): 243–47. http://dx.doi.org/10.3889/oamjms.2021.7093.
Pełny tekst źródłaStreszczenie:
AIM: The aim of the study was to evaluate effect of silver diamine fluoride (SDF) on the shear bond strength (SBS) of glass ionomer restoration to primary dentine. MATERIALS AND METHODS: Twenty extracted primary molars with no restorations or developmental anomalies were only chosen for the study. Twenty dentine slices with 2 mm thickness were prepared and then randomly allocated into two groups (n = 10 per group). For Group 1 (experimental): Dentine surfaces were treated with 38% *SDF solution (Elevate oral care, USA) for 3 min using micro-brush, followed by a 30 s rinse with water and Group 2 (Control): Dentine surfaces were treated with distilled water for 3 min then rinsed for 30 s. The cavity conditioner was applied to flat dentin of both groups for 10 s then washed and dried gently with compressed air. All the specimens were restored with *RMGIC (Riva Light Cure, SDI, Australia). SBS was determined using a Universal Testing machine and Failure mode was evaluated using stereomicroscope. Data were collected and statistically analyzed. Independent t test was used to assess differences in SBS between study groups and mode of failure was analyzed using Fisher’s exact test. Level of significance was set at p ≤ 0.05. IBM SPSS statistical software (version 26) was used to analyze the data. RESULTS: The experimental group had significantly higher mean of shear bond (11.92 ± 3.35) strength than the control group (6.99 ± 2.98) (p = 0.003). CONCLUSIONS: Primary dentin pre-treatment with 38% SDF increases the shear bond strength between RMGIC and primary dentin according to the results of this in vitro study.
27
Gibson, Nelson, i Xinjun Li. "Characterizing Cracking of Asphalt Mixtures with Fiber Reinforcement". Transportation Research Record: Journal of the Transportation Research Board 2507, nr 1 (styczeń 2015): 57–66. http://dx.doi.org/10.3141/2507-07.
Pełny tekst źródłaStreszczenie:
This study characterized the cracking resistance of two independent sets of mixtures from the FHWA full-scale accelerated loading facility and a Pennsylvania Department of Transportation trial section. Both sets had the same selection of three types of comparative materials: an unmodified control mixture, a mixture with a binder modified with styrene–butadiene–styrene (SBS), and the same control mixture modified with synthetic fiber reinforcement. Two methods of cracking characterization that can be conducted with the Asphalt Mixture Performance Tester were evaluated: simplified viscoelastic continuum damage cyclic fatigue and direct tension monotonic strength. Dynamic modulus results showed that fiber modification had less of an effect than did polymer modification. Cyclic fatigue test results predicted that both SBS- and fiber-modified mixes performed better than did the control mixes in both sets of materials. Furthermore, the cyclic fatigue tests also indicated that the SBS-modified mix performed better than did fiber under smaller fatigue strains, but the fiber-reinforced mix performed better at higher strains. Recent performance data from the FHWA full-scale accelerated loading facility agreed with the laboratory observation. The pattern where the fiber mixtures exhibited a strain-dependent performance benefit was also observed when the same continuum damage models were used but with data from a different testing methodology by means of monotonic direct tension tests. When all test data are considered, the performance benefits of fiber modification for crack resistance appear to be subtle when observed in the laboratory, but benefits are likely at relatively higher strains.
28
Deng, S., KH Chung, DCN Chan i C. Spiekerman. "Evaluation of Bond Strength and Microleakage of a Novel Metal-titanate Antibacterial Agent". Operative Dentistry 41, nr 3 (1.05.2016): E48—E56. http://dx.doi.org/10.2341/14-257-l.
Pełny tekst źródłaStreszczenie:
SUMMARY Objectives: To evaluate the effect on both bond strength and microleakage of incorporation of a novel antibacterial nanoparticulate metal-titanate complex (nMT) into a dental adhesive system. Materials and Methods: Eighty extracted human molars were prepared to determine whether incorporation of nMT into bonding agents can affect shear bond strength (SBS) and adhesive strength fatigue. SBS was measured with a universal testing machine, and the peak force at failure was recorded. An electromechanical fatigue machine was used for cyclic loading treatment of specimens. Differences in the SBS values among groups were identified using analysis of variance and Tukey post hoc analyses (α=0.05). Twenty standard Class V cavities were restored to examine microleakage when the primer/bonding resin was modified with 10 wt% nMT. Microleakage at the enamel and dentin margins was calculated as a percentage of the full length of the cavity. Results of the microleakage experiment were analyzed with paired and independent sample t-tests (α=0.05). Results: The mean (± standard deviation) shear bond strength values of before fatigue and after fatigue ranged from 21.9 (2.5) MPa to 23.9 (3.8) MPa and from 17.1 (2.5) MPa to 17.7 (2.5) MPa respectively. No statistically significant differences in failure force were observed among groups (p=0.70). Microleakage under all conditions was significantly greater in the dentin margins than in the enamel margins (p<0.05). There was no evidence that microleakage differed between the experimental groups with modified primer and bonding resin. Conclusions: Incorporating nMT into a dental adhesive system will not compromise the resin composite's tooth bonding and sealing ability.
29
Wu, Jiantao, Haoan Wang, Quan Liu, Yangming Gao i Shengjie Liu. "A Temperature-Independent Methodology for Polymer Bitumen Modification Evaluation Based on DSR Measurement". Polymers 14, nr 5 (22.02.2022): 848. http://dx.doi.org/10.3390/polym14050848.
Pełny tekst źródłaStreszczenie:
Owing to the continuous increase of traffic loads, bitumen modification has been manifested as an efficient methodology to enhance asphaltic pavement performance. Currently, the modification index, defined as the ratio of mechanical properties (e.g., complex modulus) before and after bitumen modification, is extensively adopted to evaluate the modification degree. However, bituminous materials behave as temperature-dependent, which indicates that the mechanical property varies with measured temperatures. As a result, the calculated modification index also shows temperature-dependent property, which inhibits the use of modification index. For this reason, this study introduced a method to eliminate the temperature-dependency of the modification index. In specific, a mathematical model considering the properties of modifiers was firstly established to predict the modification index-temperature curve (MI-T curve). In what follows, the temperature-dependency of modification index was analyzed to verify the proposed model on three types of modifiers, which were graphene, Styrene-Butadiene-Styrene (SBS), and Ethyl-Vinyl-Acetate (EVA), respectively. The results indicated that the developed model could efficiently predict the MI-T curves. Besides, the effective modification area (EMA) and optimal modification index (OMI) were two reasonable indicators that evaluate the bitumen modification without considering the temperature-dependency.
30
BREZO, JELENA, JOEL PARIS, RICHARD TREMBLAY, FRANK VITARO, MARK ZOCCOLILLO, MARTINE HÉBERT i GUSTAVO TURECKI. "Personality traits as correlates of suicide attempts and suicidal ideation in young adults". Psychological Medicine 36, nr 2 (7.12.2005): 191–202. http://dx.doi.org/10.1017/s0033291705006719.
Pełny tekst źródłaStreszczenie:
Background. Adults in their twenties appear to be at high risk for suicidal behaviors (SBs) and there is substantial evidence suggesting that certain personality traits may increase individual vulnerability to suicide.Method. We investigated relationships of personality traits with two SBs in a cohort (n=1140) of 21- to 24-year-old adults, representative of the general population of Quebec. Subjects were assessed using a series of structured diagnostic and personality trait questionnaires. Multivariate logistic regression analyses were employed to identify personality trait correlates of suicide-attempt history and serious suicidal ideation in the context of other known risk factors, such as psychopathology and experiences of childhood sexual and physical abuse.Results. Traits of conduct problems contributed to both suicide attempts [odds ratio (OR) 1·03, 95% confidence interval (CI) 1·01–1·06] and suicidal ideation (OR 1·04, 95% CI 1·02–1·07), while identity problems (OR 1·10, 95% CI 1·07–1·13) and gender-moderated impulsivity contributed exclusively to suicidal ideation.Conclusions. Personality traits may make independent contributions to current suicidal ideation and previous suicide attempts in certain subgroups of suicidal individuals. In order to further explore their utility as markers of suicide risk and targets of intervention further investigation in clinical samples and other cultural and age groups is necessary.
31
Berlin, Peggy, Johannes Reiner, Maria Witte, Jakob Wobar, Sabeth Lindemann, Israel Barrantes, Bernd Kreikemeyer i in. "Nod2 deficiency functionally impairs adaptation to short bowel syndrome via alterations of the epithelial barrier function". American Journal of Physiology-Gastrointestinal and Liver Physiology 317, nr 5 (1.11.2019): G727—G738. http://dx.doi.org/10.1152/ajpgi.00117.2019.
Pełny tekst źródłaStreszczenie:
Nucleotide-binding oligomerization domain-containing protein 2 ( NOD2) gene mutations are a risk factor for Crohn’s disease and also associated with worse outcome in short bowel syndrome (SBS) patients independent of the underlying disease. The aim of this study was to analyze the effect of Nod2 deficiency on barrier function and stool microbiome after extensive ileocecal resection in mice. Male C57BL6/J wild-type (WT) and Nod2-knockout (KO) mice underwent 40% ileocecal resection. Sham control mice received simple transection of the ileum. Clinical outcome was monitored daily. Barrier function was measured with Ussing chambers using FITC-4-kDa-Dextran flux, transmucosal electrical resistance, and dilution potentials. Immunofluorescence of claudin-2 was studied. Composition of the stool microbiome was assessed by 16S rRNA gene sequencing. Resected Nod2-KO mice had impaired clinical outcome compared with resected WT mice. This was accompanied by increased stool water contents and increased plasma aldosterone. Histomorphological adaptation was independent of Nod2. Barrier function studies revealed impaired sodium to chloride permeability and altered claudin-2 localization in the absence of Nod2. Resection induced decreases of bacterial diversity and a shift of bacteriodetes-to-firmicutes ratios. Ileum and cecum resection-induced increase in proteobacteria was absent in Nod2-deficient mice. Verrucomicrobia were temporarily increased in Nod2-KO mice. Nod2 deficiency functionally impairs adaptation to short bowel syndrome via a lesser increase of epithelial sodium pore permeability, altered epithelial barrier function, and the microbiome. NEW & NOTEWORTHY NOD2 gene mutations are associated with the development of severe short bowel syndrome and intestinal failure. The influence of Nod2 mutations on intestinal adaptation in experimental short bowel syndrome has not been studied yet. Here, we provide data that Nod2 deficiency worsens clinical outcome and functional adaptation under SBS conditions in mice, indicating that NOD2 is required for successful adaptation after ileocecal resection.
32
Tohidkhah, Saba, Elham Ahmadi, Mahdi Abbasi, Reza Morvaridi Farimani i Ladan Ranjbar Omrani. "Effect of Bioinductive Cavity Liners on Shear Bond Strength of Dental Composite to Dentin". BioMed Research International 2022 (18.03.2022): 1–8. http://dx.doi.org/10.1155/2022/3283211.
Pełny tekst źródłaStreszczenie:
Background. The aim of the current study was to evaluate and compare the influence of Dycal, Lime-Lite, TheraCal LC, Biodentine, resin-modified glass ionomer cement (RMGIC), and Activa BioActive as the pulp capping material on the shear bond strength of resin composite to dentin. Methods. A total of 70 extracted caries-free molars were randomly assigned to seven groups. Six test groups were covered with various protective liners: Dycal, TheraCal LC, Lime-Lite, Activa BioActive, Biodentine, and RMGIC. The control group received no liner pretreatment. Each sample was bonded to resin composite using the total-etch Tetric N bond adhesive. The samples were then tested for shear bond strength using the universal testing machine at a cross-head speed of 1 mm/min until bond failure occurred. The data were analyzed using the one-way ANOVA test followed by the Tamhane post hoc test for pairwise comparisons of the groups. Results. Independent of the type of the applied liner, all groups exhibited inferior SBS to dentin compared to the control group. TheraCal and RMGIC showed significantly higher shear bond strength than Biodentine and Dycal, which showed the lowest shear bond strength. Lime-Lite and Activa also had significantly lower SBS results than TheraCal. The mode of fracture was predominantly cohesive in Dycal, Biodentine, and TheraCal and adhesive in Activa. Conclusion. This present study concludes that the bond strength of resin composite to dentin can be affected differently using various types of liners.
33
Balbino, Vanessa, Mariana Assad, Juliana Carvalho Machado, Júlio Sérgio Marchini, Maria do Rosário Del Lama de Unamuno i Vivian Marques Miguel Suen. "Clinical and Nutritional characterization of patients with massive intestinal resection in Ribeirão Preto, SP, Brazil". International Journal of Nutrology 06, nr 01 (styczeń 2013): 010–14. http://dx.doi.org/10.1055/s-0040-1705665.
Pełny tekst źródłaStreszczenie:
ABSTRACT Background: Short bowel syndrome (SBS) is a clinical situation due to extensive intestinal resection or dysfunction of the absorptive system of the small intestine. When these patints are not submitted to nutritional therapy their maximum survival is six months. In Brazil there are few reference centers for the treatment and follow-up of these patients and information about their characterization is scarce. Objective: To describe enterectomized patients attended during the period from 1996 to 2007. Methods: All medical records of the patients attended at the Nutrology service of HCFMRP-USP were analyzed retrospectively. Data were collected and analyzed descriptively using the contingency test and the Wilcoxon- Mann-Whitney test for independent samples. Results: Thirty-eight patients with a mean age of 52 years at the time of enterectomy were analyzed, 47% of them males and 53% females. The main etiology of SBS was mesenteric ischemia (73%). Of these patients, 67% had some risk factor associated with atherosclerosis. No significant differences in eating habits were detected between the period before and after surgery. After surgery, 39% of the patients developed a significant weight loss and 79% developed some type of complication, surgical in 34%, infectious in 66% and of both types in 21%. Survival was 9.5 years. Conclusion: Extensive resections of the small bowel may be associated with atherosclerosis and represent an important nutritional risk, with a significant weight loss during the first year, which seems to be related to increased morbidity. Adequate nutritional therapy is associated with increased survival.
34
Atmaca, Zeynep, Mutahhar Ulusoy i Cagri Ulusoy. "Evaluation of Different Adhesive Resin Removal Methods after Debonding Ceramic Orthodontic Molar Tubes: A Scanning Electron Microscope Study". Scanning 2022 (16.11.2022): 1–7. http://dx.doi.org/10.1155/2022/4853035.
Pełny tekst źródłaStreszczenie:
Objectives. To evaluate and compare the impacts, bond strength, residual adhesive, and time invested on the enamel surface after debonding of recently introduced ceramic buccal molar tubes with different systems. Materials and Methods. Ceramic molar tubes were bonded to fifty-four maxillary molar teeth, and a shear bond strength (SBS) test was performed. The adhesive remnant index (ARI) scores were recorded, and the samples were divided into two groups for adhesive removal with low-speed instruments: tungsten carbide bur or diamond-coated micropolisher point. The time to clean the enamel surfaces was also noted down for each tooth. The enamel surfaces were investigated with scanning electron microscope (SEM) after adhesives were cleaned. Shapiro-Wilk’s, Kolmogorov-Smirnov’s, and Student’s independent t tests were used for statistical analysis. Results. The mean SBS value of the tested ceramic molar tubes was 9.78 ± 1.85 MPa, and the majority of the samples were scored as ARI 1 and ARI 2. No statistically significant difference between PoGo micropolisher and TCB was found in terms of time values for surface cleaning. The enamel surface characteristics of TCB for adhesive remnant removal resulted in a better enamel surface than the single-step diamond polisher when the samples were investigated by using SEM. Conclusions. Ceramic molar tubes may be an enamel-safe product for patients seeking for fully aesthetic orthodontic treatment, if used in carefully handled clinical conditions. One-step polishing systems utilised with low-speed instruments could be used confidentially for cleaning the resin remnants on enamel after orthodontic treatment.
35
Khan, Imran, i Syeda Nitasha Zahid. "The impact of Shari’ah and corporate governance on Islamic banks performance: evidence from Asia". International Journal of Islamic and Middle Eastern Finance and Management 13, nr 3 (19.06.2020): 483–501. http://dx.doi.org/10.1108/imefm-01-2019-0003.
Pełny tekst źródłaStreszczenie:
Purpose This study aims to investigate the impact of Shari’ah and corporate governance on Islamic banks performance in Asia. Design/methodology/approach The study uses hand collected data set on Shari’ah and corporate governance variables of 79 Islamic banks of 19 countries of Asia, for the period of 2011-2016. Augmented Mollah et al. (2017) composite corporate governance index into Islamic corporate governance (ICG) index by incorporate Shari’ah board’s (SBs) attributes. Two types of statistical analysis were performed; descriptive statistics, sample t-test and panel random effects regression. The analysis was further sub-sampled by considering the supervisory vs advisory, GCC vs non-GCC and large vs small effects of Shari’ah and corporate boards on Islamic banks performance. Findings The results of the baseline model reveal that Shari’ah governance-related variables are more influential in determining the financial performance of the Islamic banks. The sub-sampled data findings illustrated some interesting facts. Shari’ah supervisory vs advisory boards regression results show that the ICG index was found significant in both the models. However, when SBs are weak the general board dominates in determining the performance. GCC vs non-GCC results show a relatively good governance in non-GCC countries. While, in case of large vs small Islamic banks, banks having high total assets demonstrates sound governance characteristics. Research limitations/implications Independent, large and educated SB can play a significant role in removing the hurdles facing the Islamic banking industry and can also enhance stakeholders’ value. Originality/value This study enriches the understanding on Shari’ah governance, corporate governance and financial performance of Islamic banks in Asia.
36
Hamilton, Timothy S., Marco Berton, Sonia Antón, Lorenzo Busoni, Alessandro Caccianiga, Stefano Ciroi, Wolfgang Gässler i in. "Observations of the γ-ray-emitting narrow-line Seyfert 1, SBS 0846+513, and its host galaxy". Monthly Notices of the Royal Astronomical Society 504, nr 4 (16.04.2021): 5188–98. http://dx.doi.org/10.1093/mnras/stab1046.
Pełny tekst źródłaStreszczenie:
ABSTRACT The γ-ray-emitting galaxy SBS 0846+513 has been classified as a narrow-line Seyfert 1 (NLS1) from its spectroscopy, and on that basis would be thought likely to have a small central black hole hosted in a spiral galaxy. However, very few of the γ-ray NLS1s have high-resolution imaging of their hosts, so it is unknown how the morphology expectation holds up for the γ-emitting class. We have observed this galaxy in the J band with the Large Binocular Telescope’s LUCI1 camera and the ARGOS adaptive optics system. We estimate its black hole mass to lie between $4.2\times 10^7 \le \frac{\rm{\it{ M}}}{\text{M}_\odot } \le 9.7\times 10^7$, using the correlation with bulge luminosity, or $1.9\times 10^7 \le \frac{\rm{\it{ M}}}{\text{M}_\odot } \le 2.4\times 10^7$ using the correlation with Sérsic index. Our favoured estimate is 4.2 × 107 M⊙, putting its mass at the high end of the NLS1 range in general but consistent with others that are γ-ray emitters. These estimates are independent of the broad-line region viewing geometry and avoid any underestimates due to looking down the jet axis. Its host shows evidence of a bulge + disc structure, from the isophote shape and residual structure in the nuclear-subtracted image. This supports the idea that γ-ray NLS1 may be spiral galaxies, like their non-jetted counterparts.
37
Al-Jawad, Ola Abbas, i Shakir Al-Busaltan. "Statistical Modeling for the Characteristics of Open Graded Friction Course Asphalt". Journal of University of Babylon for Engineering Sciences 27, nr 1 (11.02.2019): 366–81. http://dx.doi.org/10.29196/jubes.v27i1.2176.
Pełny tekst źródłaStreszczenie:
An open-graded friction course (OGFC) is a special type surface layer of traditional Dense Graded Hot Mix Asphalts (DGHMA) pavement that is increasingly being used around the world due to its various benefits, such as, frictional, safety and environmental, etc. In this research, selective laboratory OGFC properties were statistically modeled depends on mix design inputs for two purposes or aims; mix inputs significant and prediction the OGFC properties according mix inputs. Principally, Indirect Tensile Strength (ITS), water sensitivity (TSR), and permeability (K) were selected from mechanical, durability, and volumetric properties, respectively as an output property; they represent the dependent variables for each model. While, fillers as conventional mineral filler or Ordinary Portland Cement (CMF, or OPC), binder content (BC), and polymer content (SBS) are represented inputs or the independent variables for all models. The generated models offered a vital achievable tool for prediction (e.g., their R² are 0.781, 0.82 1and 0.820, respectively, for the mentioned model’s properties), also it helped to scale the significant of each independent variable (e.g., filler type significantly affect water sensitivity properties, its correlation was 0.752). This study reveals that the statistical modeling is achievable and offers a dynamic tool to describe the characteristics and performance of OGFC mixture in term volumetric, mechanical and durability properties.
38
Siraj, Sarah, Tariq Masoodi, Abdul K. Siraj, Saud Azam, Zeeshan Qadri, Sandeep K. Parvathareddy, Rong Bu i in. "APOBEC SBS13 Mutational Signature—A Novel Predictor of Radioactive Iodine Refractory Papillary Thyroid Carcinoma". Cancers 14, nr 6 (21.03.2022): 1584. http://dx.doi.org/10.3390/cancers14061584.
Pełny tekst źródłaStreszczenie:
Standard surgery followed by radioactive iodine (131I, RAI) therapy are not curative for 5–20% of papillary thyroid carcinoma (PTC) patients with RAI refractory disease. Early predictors indicating therapeutic response to RAI therapy in PTC are yet to be elucidated. Whole-exome sequencing was performed (at median depth 198x) on 66 RAI-refractory and 92 RAI-avid PTCs with patient-matched germline. RAI-refractory tumors were significantly associated with distinct aggressive clinicopathological features, including positive surgical margins (p = 0.016) and the presence of lymph node metastases at primary diagnosis (p = 0.012); higher nonsilent tumor mutation burden (p = 0.011); TERT promoter (TERTp) mutation (p < 0.0001); and the enrichment of the APOBEC-related single-base substitution (SBS) COSMIC mutational signatures 2 (p = 0.030) and 13 (p < 0.001). Notably, SBS13 (odds ratio [OR] 30.4, 95% confidence intervals [CI] 1.43–647.22) and TERTp mutation (OR 41.3, 95% CI 4.35–391.60) were revealed to be independent predictors of RAI refractoriness in PTC (p = 0.029 and 0.001, respectively). Although SBS13 and TERTp mutations alone highly predicted RAI refractoriness, when combined, they significantly increased the likelihood of predicting RAI refractoriness in PTC. This study highlights the APOBEC SBS13 mutational signature as a novel independent predictor of RAI refractoriness in a distinct subgroup of PTC.
39
Juárez, D., S. Ferrándiz, R. Balart, M. J. Reig i M. A. Peydró. "Rheological Characterization and Mathematical Modeling of a SEBS Blend for Industrial Applications where Nowadays Liquid Silicone Rubber is Used". Key Engineering Materials 502 (luty 2012): 109–14. http://dx.doi.org/10.4028/www.scientific.net/kem.502.109.
Pełny tekst źródłaStreszczenie:
SEBS (styrene-ethylene/butylene-styrene) is a hydrogenated SBS used as a compatibilizer of other thermoplastic or as a blend to improve the properties (mainly impact). There is very little information about SEBSs research, independent of other materials. This study focuses on a blend from the providers SEBS extreme hardness (50% Shore-A 5 and 50% Shore-A 90) in order to analyze the miscibility of mixed materials from the storage of 2 references only. It has been used the thermoplastic elastomer Megol TA® SEBS, whose characteristics make it special due to the wide range of hardness and transparency, and can be obtained blend for industrial applications where nowadays liquid silicone rubber is used. Next step is rheological characterization of the blend, analyzing the viscosity for subsequent mathematical modeling. Finally, in order to reproduce the rheological behavior of materials during the injection process, Autodesk Moldflow Inside 2010 CAE (Computer Aided Engineering) tool has been used with Cross-WLF model parameters, and compared with tests injected.
40
Magdis, Georgios E. "Molecular gas across cosmic time". Proceedings of the International Astronomical Union 15, S352 (czerwiec 2019): 205–9. http://dx.doi.org/10.1017/s1743921319008469.
Pełny tekst źródłaStreszczenie:
AbstractWe have entered an era where the gas mass estimates of distant galaxies do not rely on a single tracer but rather on an inventory of different and independent methods, much like the case for the determination of the star formation rate (SFR) of the galaxies. This is crucial as the traditional Mgas tracers, i.e. low-J CO transition lines and dust continuum emission are becoming highly uncertain as we move to higher redshifts due to metallicity and CMB effects. Here, we present a homogeneous and statistically significant investigation of the use of atomic carbon as an alternative Mgas tracer (Valentino et al.2018) and provide evidence of optically thick far-IR emission in high−z starbursts that point towards higher dust temperatures and lower dust and gas mass estimates than previously inferred (Cortzen et al.2019, submitted). Finally, we present direct observations of the effect of the CMB on the far-IR SEDs of high-z SBs, manifested by unphyscally large (β = 2.5–3.5) apparent spectral indexes in R-J tail (Jin et al. 2019, submitted).
41
Yennu, Sriram, Dave Balachandran, Sandra L. Pedraza, Elyssa A. Berg, Gary B. Chisholm, Akhila Sunkepally Reddy, Janet L. Williams i Eduardo Bruera. "Frequency and characteristics of cancer-related drowsiness (CRD or excessive daytime sleepiness) in patients with advanced cancer: Results of a prospective survey at a tertiary cancer center." Journal of Clinical Oncology 32, nr 31_suppl (1.11.2014): 131. http://dx.doi.org/10.1200/jco.2014.32.31_suppl.131.
Pełny tekst źródłaStreszczenie:
131 Background: CRD is extremely distressing but treatable symptom to the advanced cancer patients (ACP). There are limited studies to evaluate the frequency and characteristics of CRD. The aim of this study was to identify the frequency, and factors associated with severity of CRD. Secondary aim was to determine the screening performance Edmonton Symptom Assessment Scale (ESAS)-drowsiness item against the Epworth Sleepiness Scale (ESS). Methods: We prospectively assessed 180 consecutive ACP at a tertiary cancer hospital. After obtaining signed consent, the patients completed ESAS, Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI); ESS (≥10 diagnostic of CRD), Hospital Anxiety Depression Scale (HADS), STOP-Bang Screening Scale (SBS), and Screening tool for RLS. We determined epidemiological performance, spearman correlations, regression analysis, receiver operated characteristics of CRD. Results: Of the180 patients assessed, 51% were female, CRD was found in 50% ACP, median scores(IQR) ESS: 11(7-14); ESAS- drowsiness item was 5 (2-6); PSQI was 8(5-11); ISI (13 (5-19); SBS 3(2-4); HADS-D 6(3-10). Sleep apnea was found in 61%; and RLS in 38%. ESAS-D was associated with other ESAS items[r, p-value] Sleep (0.38, < 0.0001); pain (0.3, < 0.0001); fatigue(0.51, < 0.0001); depression(0.39, < 0.0001); anxiety(0.44, < 0.0001); shortness of breath(0.32, < 0.0001); anorexia(0.36, < 0.0001), FWB(0.41, < 0.0001), and ESS (0.24, 0.001), Opioid dose [MEDD] (0.19, 0.01). Multivariate analysis found no independent predictors except ISI (OR 2.35; 0.036), ESAS Fatigue (OR 9.08, <0.0001), ESAS Anxiety (3.0, 0.009); feeling of well-being (OR 2.27, p=0.04). An ESAS- drowsiness cut-off score of ≥ 3(of 10) resulted in a sensitivity and specificity of 81% and 32% and of 70% and 44% in the training and validation samples, respectively. Conclusions: Clinically significant CRD was associated with increased fatigue, anxiety, sleep disturbance and worse feeling of well-being. These symptoms should be routinely assessed and treated in ACP with CRD. ESAS-drowsiness score of ≥3 of 10 is most useful for screening CRD.
42
Zeki, Mousa, i Shakir Al-Busaltan. "Developing Laboratory Performance Models for Thin Asphalt Overlay Mixtures". Journal of University of Babylon for Engineering Sciences 27, nr 1 (11.02.2019): 382–95. http://dx.doi.org/10.29196/jubes.v27i1.2186.
Pełny tekst źródłaStreszczenie:
Statistical modeling is utilized effectively to development relation/s between the dependent variables and independent variables. In other words, it describes how one or more random variables are related to one more other variables. Building verified models can help in predicting performance characteristics, and saving time and money. This study aims to present a statistical models which help to understand the significance of the different parameters in characterizing the performance of the Thin Asphalt Overlay (TAO). The experimental program included: design the thin asphalt overlay mixtures using one gradation type (9.5 Nominal Maximum Aggregate Size NMAS), three filler types (conventional mineral filler, Ordinary Portland Cement, and Quick lime), and five percentages of asphalt content to identify the optimum asphalt content. Then, Styrene Butadiene Styrene (SBS) modified polymer binder was introduced for performance enhancement. Performance tests were used to evaluate TAO mixture in term of some main namely, volumetric, mechanical, and durability properties are (bulk density, indirect tensile strength and tensile strength ratio). Statistical Product and Service Solutions (SPSS) software (Version 24) was used as a tool for models building. To find the most accurate statistical models, linear and nonlinear regression was achieved. This study demonstrates that the using statistical modeling is achievable and offer a vital tool to describe the characteristics and performance of the TAO mixture in term volumetric, mechanical and durability properties.
43
Zhang, Fang, Min Shi, Na Zhao, Peng Guo, Jun Hou i Yang Liu. "Whole exome sequencing facilitated diagnosis of patients with multiple mucinous neoplasms of the female genital tract." Journal of Clinical Oncology 40, nr 16_suppl (1.06.2022): e17513-e17513. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17513.
Pełny tekst źródłaStreszczenie:
e17513 Background: The differential diagnosis is challenging in clinical practice, especially among gastric-type AD of the cervix with ovarian metastases, multiple primary mucinous neoplasm in cervix and ovary, and synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT). Previous studies have revealed that next-generation sequencing might be a feasible tool in identifying the origin of tumor. Herein, whole exome sequencing (WES) was performed to distinguish patients with metastatic disease. Methods: WES analysis was performed on 28 tumors and 7 normal tissues derived from 8 patients. Each patient had one lesion of the cervix uteri. Most of them had lesions at other anatomical sites, including corpus uteri, ovary, oviduct, vermiform appendix and omentum. Mutations signatures and clonal evaluation inferred from single-nucleotide/copy number variants were explored. Results: Previous studies of multiple types of cancer have identified more than 40 single-base substitution (SBS) signatures. SBS3/6 referring to defective DNA mismatch repair and SBS10 reported in both uterus and colorectal AD were significantly enriched in this study. Next, we found no significant distribution of SBS3/6/10 among tumors at different anatomical sites. These findings indicate that primary cervical/ovarian AD with metastases other than multiple primary cancers was the predominant histology in 8 patients. The association of genomic alterations in POLE/ POLD1/HRR pathway with the distribution of SBS signatures was explored. SBS3 had a trend of significant distribution (p = 0.01) in four patients who had germline alterations in HRR pathway. Furthermore, SBS10 was significantly enriched (p = 0.009) in 2 patients with germline POLE/POLD1 alterations. Clonal evolution analyses revealed that 2 patients were identified as having SMMN-FGT, and other 6 patients had dominant clones in different tumors, which suggested a . Notably, besides the dominant clones and subclones, some tumors also exhibited extra independent clones, which might be the mixed histology of primary and metastatic tumor. In addition, we found the difference of overall survival in patients having gastric-type AD of the cervix with ovarian metastases and cervical AD patients with different FIGO stage disease based on SEER database data. Conclusions: Our study demonstrated that WES might be a feasible tool to distinguish patients having primary cervical AD with multiple metastases from those with multiple primary cancers of the female genital tract, which suggests that WES proved valuable in facilitating the diagnostic workup. A prospective, multi-center, large cohort study is needed to investigate the performance of WES in identifying the origin of tumors in patients with multiple tumors of the FGT.
44
Hoang, Tran, Gianfranco Bittar, Purnima Sravanti Teegavarapu, Martha P. Mims i Gustavo Rivero. "Tobacco Use Predicts Unique Mutagenesis Signature in Acute Myelogenous Leukemia". Blood 138, Supplement 1 (5.11.2021): 1297. http://dx.doi.org/10.1182/blood-2021-154173.
Pełny tekst źródłaStreszczenie:
Abstract Background: Endogenous and exogenous processes are active in leukemia initiation. Single-base substitution (SBS) data permits aggregation into mutational signatures [MS] with potential for clinical application. Acetaldehyde and Benzo [a] pyrene (BaP) are tobacco mutagens that "drive" signature SBS4 [Catalog of Somatic Mutations in Cancer (COSMIC) https://cancer.sanger.ac.uk/signatures/sbs/] in lung cancer characterized by C>A transversion. This specific MS is associated with favorable response to immune-checkpoint therapy (ICT). Previous epidemiologic data correlate smoking with cancer including leukemia. Tobacco mutagens are ubiquitously distributed in organs once inhaled. However, how mutagenicity develops in hemopoietic stem cell/progenitor is unknown. In this study, our primary objective was to investigate the incidence of MS among patients (pt) diagnosed with Acute Myelogenous Leukemia (AML) with smoking exposure. Methods: After IRB approval, we performed retrospective analysis using the BCM AML database. Data from 58 AML pt was available. For all analysis, current and past smoking were aggregated into "positive exposure". SBSs (C>A, C>G, C>T, T>C, T>G, G>C, G>A, GT and AG) in smokers and never smoker were annotated from ELN 2017 predefined subgroups [i.e. CEBPA, NPM1, P53, ASLX1, RUNX1 and FLT3ITD] and all additional mutations in individual pt. We used descriptive statistics to detect differential clinical predictors for smoking induced MS. Chi-square was used to determine association between SBSs and smoking history. Stepwise logistic regression allowed identification of independent MS that correlated with smoking. Results: Median age for 58 AML pt was 65.5 years [y] (range, 22-89) and 58.3% were male. Smokers were 26/58 (44.8%). Whites, African Americans, Hispanics and Asians comprised 35/60 (58.3%), 7/60 (7.1%), 16/60 (26.6%) and 2/60 (2.3%), respectively. 112 myeloid mutations [91 SBSs, 16 duplications, 16 deletions, and 3 insertions] were recorded. 32/58 (55.1%) had positive smoking exposure. Previous reports suggest that C>A [COSMIC=SBS4], G>C [COSMIC= SBS2 and SBS13] and T>C [COSMIC=SBS5] retain strong smoking association with cancer. However, in addition to C>A [HR=0.10 (0.01-0.6), p=0.02], our logistic model identified G>A, HR=0.12 (0.02-0.4), p=0.002, as predictors of exposure. C>A+G>A MS was observed in 19/25 (76%) of AML pt with smoking exposure, OR=6.56 (1.8-23.9), p=0.002. By ELN-2017 defined subgroups, P53, ASXL1, RUNX1, FLT3 and NPM1 mut were detected in 11/58 (18.9%), 5/58 (8.6%), 4/58 (6.8%), 13/58 (22.4%) and 5/58 (8.6%). RAS was seen in 12/58 (20.6%), IDH 12/58 (20.6%), DNMT3A 10/58 (17.2%) and TET2 7/58 (12%). Interestingly, among smokers exhibiting or not C>A+G>A SBP substitution, P53 was identified in 3/3 (100%) v 0/3 (0%), p=0.05 and RAS in 75% v 25%, p=0.08. Conclusions: Our data suggest that C>A and G>A SBS substitutions are frequently observed in AML pt with smoking exposure. Hemopoietic stem cell/progenitors exposed to smoking products may initiate similar SBSs substitutions as those observed in tobacco induced solid tumors. Previously, lung cancer studies demonstrated that TP53 and KRAS mutations tumors exhibited high rate of C>A transversion associated with tumor-infiltrating lymphocytes (TIL) and high program-death 1 ligand (PD-L1) expression. Further similar studies are needed in adult diagnosed with P53 AML. Figure 1 Figure 1. Disclosures Mims: IDEC: Current holder of individual stocks in a privately-held company; Biogen: Current holder of individual stocks in a privately-held company; Incyte: Research Funding; Pfizer: Research Funding; AVEO: Research Funding; Celgene: Research Funding.
45
Maniaty, Tony. "From Vietnam to Iraq: Negative trends in television war reporting". Pacific Journalism Review : Te Koakoa 14, nr 2 (1.09.2008): 89–101. http://dx.doi.org/10.24135/pjr.v14i2.946.
Pełny tekst źródłaStreszczenie:
In 1876, an American newspaperman with the US 7th Cavalry, Mark Kellogg, declared: ‘I go with Custer, and will be at the death.’ This overtly heroic pronouncement embodies what many still want to believe is the greatest role in journalism: to go up to the fight, to be with ‘the boys’, to expose yourself to risk, to get the story and the blood-soaked images, to vividly describe a world of strength and weakness, of courage under fire, of victory and defeat—and, quite possibly, to die. So culturally embedded has this idea become that it raises hopes among thousands of journalism students worldwide that they too might become that holiest of entities in the media pantheon, the television war correspondent. They may find they have left it too late. Accompanied by evolutionary technologies and breathtaking media change, TV war reporting has shifted from an independent style of filmed reportage to live pieces-to-camera from reporters who have little or nothing to say. In this article, I explore how this has come about; offer some views about the resulting negative impact on practitioners and the public; and explain why, in my opinion, our ‘right to know’ about warfare has been seriously eroded as a result.
Caption: The technology has improved, but the risks do not go away. Freelancer John Martinkus, author of A Dirty Little War about East Timor, seen here on assignment for SBS Dateline in Kunar province, Afghanistan, in 2005, was kidnapped in Iraq—but he managed to escape. Others have not been so fortunate.
46
Theofanidis, Dimitrios, Antigoni Fountouki, Christos Savopoulos, Apostolos Hatzitolios, Xenofon Fitsioris i Jiobst Rudolf. "Contemporary stroke care delivered in a specialised stroke bay, a neurology ward and a medical ward in Greece". Health & Research Journal 5, nr 4 (28.10.2019): 163. http://dx.doi.org/10.12681/healthresj.22070.
Pełny tekst źródłaStreszczenie:
Introduction: Currently in Greece there are only two ‘stroke bays’ (SBs) and their efficacy compared to standard ward treatment has not been evaluated.Aim: To provide baseline data on stroke case-mix and compare death rates in two Greek hospitals (A+B, i.e. with & without a SB).Material and Methods: One hundrend sixty four acute stroke patients from two hospitals were consecutively selected in order to explore approaches to stroke care in three different types of care delivery settings. A descriptive design with group comparisons was employedand data gathering included patient case mix, age and length of stay (LOS), neurological status and death rates. Kaplan-Meier curves we reused for survival analysis and independent samples t test and Z test for group comparisons at p<0.05.Results: Of the 164 patients, 88 (44.4%, female) werein hospital A and 76 (42.1%, female) in hospital B. The mean age was 65.7 and 69.1 years respectively, LOS was 7.6 (3-18) and 7.3 days (1-26), while death rate was 6.8% and 10.5% respectively.Discussion: Survival analysis for the two hospitalsshowed that there are no statistically significant differences regarding death and survival rates between the two hospitals, even when one had a SB. Yet, the SB shows a statistically significant reduction in overall LOS.Conclusions: In societies where stroke units are not yet established, a SB might be an economical way of making use of (limited) available resources and raising nursing and medical standards of care by motivating the full potential of staff involved.
47
Wu, Chien-Te, Hao-Chuan Huang, Shiuan Huang, I.-Ming Chen, Shih-Cheng Liao, Chih-Ken Chen, Chemin Lin i in. "Resting-State EEG Signal for Major Depressive Disorder Detection: A Systematic Validation on a Large and Diverse Dataset". Biosensors 11, nr 12 (6.12.2021): 499. http://dx.doi.org/10.3390/bios11120499.
Pełny tekst źródłaStreszczenie:
Major depressive disorder (MDD) is a global healthcare issue and one of the leading causes of disability. Machine learning combined with non-invasive electroencephalography (EEG) has recently been shown to have the potential to diagnose MDD. However, most of these studies analyzed small samples of participants recruited from a single source, raising serious concerns about the generalizability of these results in clinical practice. Thus, it has become critical to re-evaluate the efficacy of various common EEG features for MDD detection across large and diverse datasets. To address this issue, we collected resting-state EEG data from 400 participants across four medical centers and tested classification performance of four common EEG features: band power (BP), coherence, Higuchi’s fractal dimension, and Katz’s fractal dimension. Then, a sequential backward selection (SBS) method was used to determine the optimal subset. To overcome the large data variability due to an increased data size and multi-site EEG recordings, we introduced the conformal kernel (CK) transformation to further improve the MDD as compared with the healthy control (HC) classification performance of support vector machine (SVM). The results show that (1) coherence features account for 98% of the optimal feature subset; (2) the CK-SVM outperforms other classifiers such as K-nearest neighbors (K-NN), linear discriminant analysis (LDA), and SVM; (3) the combination of the optimal feature subset and CK-SVM achieves a high five-fold cross-validation accuracy of 91.07% on the training set (140 MDD and 140 HC) and 84.16% on the independent test set (60 MDD and 60 HC). The current results suggest that the coherence-based connectivity is a more reliable feature for achieving high and generalizable MDD detection performance in real-life clinical practice.
48
Chidambaram, S., KV Baburam Reddy, K. Supradeep Kumar, C. Hanumantha Rao, HC Girish i Sanjay Murgod. "Flowable Composite an Alternative Orthodontic Bonding Adhesive: An in vitro Study". Journal of Contemporary Dental Practice 14, nr 5 (2013): 883–86. http://dx.doi.org/10.5005/jp-journals-10024-1420.
Pełny tekst źródłaStreszczenie:
ABSTRACT Objective To determine the clinical applicability of Ormocer based flowable adhesive (Admira flow) in comparison with BisGMA based adhesive (Transbond XT) and Ormocer based packable adhesive (Admira). Materials and methods Sixty human premolars, divided into group I (n = 20) Transbond XT, group II (n = 20) Admira and group III (n = 20) Admira flow were bonded with metal brackets using adhesives. Brackets were debonded in shear on an Instron universal testing machine with a crosshead speed of 1 mm per minute. The mode of bond failure was determined by modified ARI index. Results The results obtained from SBS evaluation and modified ARI showed highest shear bond strength for Transbond XT (SD 11.64) 3.68 followed by Admira flow (SD 11.0) 2.87 and least for Admira (SD 9.42) 2.21. However, the difference was not statistically significant, but an intergroup comparison done using Independent student ‘t’ test, showed statically significant difference between Transbond XT and Admira. Kaplan-Meier survival analysis showed least survival median value for Admira, but the survival median value is not statistically significant among the three groups. All groups had modified ARI score of three (60-70%), suggestive of cohesive type of failure. Conclusion The in vitro study showed that flowable Ormocer can be an good alternative to commonly used BisGMA based adhesive but the its efficacy needs clinical assessment through a survival analysis. Clinical significance Admire flow can definitely be considered as an alternative bonding system due to their comparable bond strength and debonding characters and reported properties of biocompatibility. How to cite this article Kumar KS, Rao CH, Reddy KVB, Chidambaram S, Girish HC, Murgod S. Flowable Composite an Alternative Orthodontic Bonding Adhesive: An in vitro Study. J Contemp Dent Pract 2013;14(5):883-886.
49
Nichol, Donna, Siân Jones, Samuel V. Angiouli, Laurel Keefer, Monica Nesselbush, Naomi Sengamalay, James White i in. "Pan-Cancer assessment of tumor mutational burden using a comprehensive genomic profiling assay." Journal of Clinical Oncology 36, nr 5_suppl (10.02.2018): 157. http://dx.doi.org/10.1200/jco.2018.36.5_suppl.157.
Pełny tekst źródłaStreszczenie:
157 Background: Checkpoint inhibitors (CPIs) have been approved for frontline or subsequent therapies in several indications over the last few years. While patient response can be remarkably durable, many patients do not benefit. Current clinical biomarkers of response to CPIs include microsatellite instability (MSI) and PD-L1 expression. While a proportion of many solid tumors display microsatellite instability, the prevalence is often very low. Similarly, while clinically informative, PD-L1 expression alone is not sufficient to predict therapeutic outcomes with high accuracy. The lack of predictive biomarkers for response highlights the need for improved biomarkers with greater prevalence across tumor types to predict response to CPIs. Multiple clinical studies have revealed that high tumor mutational burden (TMB) is associated with improved clinical response. Methods: Here, we describe the development of a method that can be used to accurately infer mutational burden from a discrete set of targeted regions of interest across the exome. Initially, we performed an assessment of the accuracy across multiple bioinformatics methods for identification of individual sequence mutations (SBS/indels) using orthogonally validated data together with publicly available TCGA whole-exome sequencing data. The targeted regions were then isolated from these datasets to demonstrate analytical performance across several different solid tumor types. Finally, we evaluated independent non-small cell lung cancer (NSCLC) and colorectal carcinoma (CRC) cohorts to demonstrate the analytical accuracy of the assay and bioinformatics approach for determination of mutational burden when compared to whole exome sequencing. Results: In summary, high concordance was observed across a large dynamic range of mutations per megabase of coding sequence. Conclusions: Our data indicate that the assay can be used to accurately determine mutational burden in a range of tumor types, across a spectra of potential mutational burden cut-offs using automated, complex mutation identification algorithms.
50
H-H. Hsu-Hage, Bridget, K. C. Tang, Rebecca Jie Li, Vivian Lin, Tony Chow i Frank Thien. "A Qualitative Investigation into the Use of Health Services among Melbourne Chinese". Australian Journal of Primary Health 7, nr 3 (2001): 38. http://dx.doi.org/10.1071/py01044.
Pełny tekst źródłaStreszczenie:
Understanding health service utilisation by community groups can be used to enhance cost-effective service delivery planning. In an inquiry into general health needs, and experiences with health service utilisation by Chinese living in Melbourne, we conducted a series of focus group discussions to explore community health-seeking behaviour. Seven focus groups were drawn from community groups and bilingual health workers in the period September-October 1999. Discussions were carried out in dialect familiar to the participants, facilitated by trained multilingual researchers, tape recorded and transcribed in Chinese and then translated into English. Cross validation was carried out by an independent researcher. Themes that emerged from these discussions included common pathways to care seeking, barriers to the use of health care services, general health concerns, and perceived validity of health information sources. Participants opt for self care when feeling unwell if the condition is perceived as ?not severe?. Use of over-the-counter medication is usually the first course of action. There is a tendency to ?wait and see? when feeling unwell. The use of Traditional Chinese Medicine Practitioners (TCMP) is common, while continuing to see Orthodox Western Medicine practitioners. There are, however, common concerns about the quality of care provided by TCM practitioners and their qualifications. Language, transport, and cost are among other barriers that undermine the use of health care services. Participants reported diabetes, heart disease risk factors, peptic ulcer, hay fever and asthma, poor vision, dental problems, social isolation, and gambling among the most common health concerns. Participants accepted health information from a wide range of sources and placed greater trust in material disseminated by SBS Chinese Radio Programs and the Chinese Health Foundation; an established community organisation run by voluntary health professionals. In conclusion, the study confirmed a number of patterns by which the Chinese community sought and utilised health services and associated factors.