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Artykuły w czasopismach na temat "RNA-binding protein"
Sawicka, Kirsty, Martin Bushell, Keith A. Spriggs i Anne E. Willis. "Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein". Biochemical Society Transactions 36, nr 4 (22.07.2008): 641–47. http://dx.doi.org/10.1042/bst0360641.
Pełny tekst źródłaSingh, Arunima. "RNA-binding protein kinetics". Nature Methods 18, nr 4 (kwiecień 2021): 335. http://dx.doi.org/10.1038/s41592-021-01122-6.
Pełny tekst źródłaOttoz, Diana S. M., i Luke E. Berchowitz. "The role of disorder in RNA binding affinity and specificity". Open Biology 10, nr 12 (grudzień 2020): 200328. http://dx.doi.org/10.1098/rsob.200328.
Pełny tekst źródłaEck, Andrew G., Kevin J. Lopez i Jeffrey O. Henderson. "RNA-binding Motif Protein 45 (Rbm45)/Developmentally Regulated RNA-binding Protein-1 (Drbp1): Association with Neurodegenerative Disorders". Journal of Student Research 7, nr 2 (31.12.2018): 33–37. http://dx.doi.org/10.47611/jsr.v7i2.417.
Pełny tekst źródłaPopper, Bastian, Tom Scheidt i Rico Schieweck. "RNA-binding protein dysfunction in neurodegeneration". Essays in Biochemistry 65, nr 7 (grudzień 2021): 975–86. http://dx.doi.org/10.1042/ebc20210024.
Pełny tekst źródłaChoi, Kwang-Ho, Seong-Ryul Kim, Sung-Wan Kim, Tae-Won Goo, Seok-Woo Kang i Seoung-Won Park. "Characterization of the RNA binding protein-1 gene promoter of the silkworm silk grands". Journal of Sericultural and Entomological Science 52, nr 1 (30.04.2014): 39–44. http://dx.doi.org/10.7852/jses.2014.52.1.39.
Pełny tekst źródłaDeLisle, A. J. "RNA-Binding Protein from Arabidopsis". Plant Physiology 102, nr 1 (1.05.1993): 313–14. http://dx.doi.org/10.1104/pp.102.1.313.
Pełny tekst źródłaStrack, Rita. "Predicting RNA–protein binding affinity". Nature Methods 16, nr 6 (30.05.2019): 460. http://dx.doi.org/10.1038/s41592-019-0445-4.
Pełny tekst źródłaPurnell, B. A. "Noncoding RNA helps protein binding". Science 350, nr 6263 (19.11.2015): 923–25. http://dx.doi.org/10.1126/science.350.6263.923-o.
Pełny tekst źródłaChen, Xiuzhen, i Christine Mayr. "A working model for condensate RNA-binding proteins as matchmakers for protein complex assembly". RNA 28, nr 1 (27.10.2021): 76–87. http://dx.doi.org/10.1261/rna.078995.121.
Pełny tekst źródłaRozprawy doktorskie na temat "RNA-binding protein"
Crombie, Catriona Ann. "Histone hairpin binding protein, an RNA binding protein, essential for development". Thesis, University of Aberdeen, 2003. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602058.
Pełny tekst źródłaZhong, Jun. "A double-stranded RNA binding protein that is important for murine spermatogenesis and growth /". Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/10301.
Pełny tekst źródłaKok, Kin-hang. "Roles of human double-stranded RNA binding proteins TRBP and PACT in RNA interference". Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B38523218.
Pełny tekst źródłaKok, Kin-hang, i 郭健恆. "Roles of human double-stranded RNA binding proteins TRBP and PACT in RNA interference". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B38523218.
Pełny tekst źródłaPrichard, Lisa. "The role of the IQ motif, a protein kinase C and calmodulin regulatory domain, in neuroplasticity, RNA processing, and RNA metabolism /". Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/6302.
Pełny tekst źródłaLoushin, Newman Carrie Lee. "Characterization of QKI RNA binding function /". Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004323.
Pełny tekst źródłaDavies, Holly Gibs. "MSY4, a sequence-specific RNA binding protein expressed during mouse spermatogenesis /". Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/10307.
Pełny tekst źródłaWolf, Joshua Jaeger. "Post-transcriptional coordination by an RNA-binding protein". Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57893.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references.
RNA-binding proteins can regulate the stability, localization, and translation of their target mRNAs. Post-transcriptional regulation can orchestrate dynamic changes in gene expression, and can coordinate multiple cellular processes in response to various stimuli. Filamentous growth in Saccharomyces cerevisiae is a morphogenetic switch that occurs in response to nitrogen starvation and requires alterations in cell growth, cell cycle, and cell wall functions. Tyl element retrotransposition is also induced under conditions of nitrogen starvation. I describe a role for the RNA-binding protein Khdl in regulating these two responses to environmental stress through its mRNA targets. I identified the RNA targets of Khdl using in vivo crosslinking and immunoprecipitation (CLIP), combined with deep sequencing. This produced a high-resolution map of Khdl binding sites across the transcriptome, and provided unprecedented insight into its biological functions. Khdl regulates multiple post-transcriptional regulatory loops to coordinate the components of filamentous growth and Tyl retrotransposition. Although similar mechanisms were known to transcriptionally regulate these processes, the posttranscriptional coordination is a novel discovery. The feed-forward regulation that Khdl confers on FLO11, which encodes a protein required for filamentous growth, enables asymmetric expression between mother and daughter cells to switch between filamentous and yeast form growth. In this thesis, I describe regulation of gene expression by RNA-binding proteins, methods to identify their target transcripts and recognition sequences, the KH domain, known functions of Khdl, and the phenotypes it coordinates. My work represents the first application of CLIP to budding yeast, and the growing understanding of RNA-binding proteins in this organism facilitated the placement of Khdl into its posttranscriptional regulatory network. While many questions remain regarding the role Khdl plays in regulating cellular activities, this thesis addresses its direct role in key processes.
by Joshua Jaeger Wolf.
Ph.D.
Zinnall, Ulrike. "Functional characterization of the RNA-binding protein HDLBP". Doctoral thesis, Humboldt-Universität zu Berlin, 2021. http://dx.doi.org/10.18452/23301.
Pełny tekst źródłaThe secretory pathway is essential for proper cell functioning and starts when mRNAs encoding membrane and secretory proteins are targeted to the endoplasmic reticulum (ER). However, little is known about the contribution of RNA-binding proteins to the recognition, localization and translation of ER-localized mRNAs. In this work, we characterized the human RNA-binding protein HDLBP. We identified that HDLBP binds to more than 80% of all ER-localized mRNAs by PAR-CLIP, cell fractionation and RNA-sequencing experiments. Analysis of the HDLBP binding motif showed that it predominantly binds to a CU-containing motif and forms high affinity multivalent interactions primarily in the coding sequence (CDS) of ER-localized mRNAs. In contrast, we identified that cytosolic HDLBP mRNA targets show less HDLBP binding sites randomly distributed between the CDS or 3’ untranslated regions. This indicates that ER-localized mRNAs per se differ from cytosol-localized mRNAs in their sequence composition with regard to HDLBP binding sites. Further PAR-CLIP analysis revealed that HDLBP interacts with RNA components of the signal recognition particle (SRP) and the 40S ribosomal subunit. We identified by BioID experiments proteins in close proximity to HDLBP and confirmed the association of HDLBP with components of the translational apparatus and the SRP. Functional studies using CRISPR-Cas9 HDLBP knockout (KO) cell lines in combination with ribosome profiling demonstrated that HDLBP promotes the translation of its ER-localized target mRNAs. We validated this finding by pSILAC experiments and detected the corresponding decrease in protein synthesis of proteins encoded by mRNAs that are bound by HDLBP and ER-localized. Lastly, in vivo experiments with nude mice showed that HDLBP KO resulted in a decrease of lung tumor formation highlighting the relevance of HDLBP for tumor progression. Overall, these results demonstrate a general function for HDLBP in the translation of ER-localized mRNAs.
Moro, Alberto Maria. "Functional characterization of the RNA binding protein RALY". Doctoral thesis, University of Trento, 2013. http://eprints-phd.biblio.unitn.it/1086/1/Albertomaria_Moro_thesis_Final_version.pdf.
Pełny tekst źródłaKsiążki na temat "RNA-binding protein"
Ren-Jang, Lin, red. RNA-protein interaction protocols. Wyd. 2. Totowa, N.J: Humana, 2008.
Znajdź pełny tekst źródłaSymposium on RNA Biology (2nd 1997 North Carolina Biotechnology Center). Symposium on RNA Biology: RNA tool and target : held at North Carolina Biotechnology Center, Research Triangle Park, North Carolina, USA, October 17-19, 1997. [Oxford]: Oxford University Press, 1997.
Znajdź pełny tekst źródłaRen-Jang, Lin, red. RNA-protein interaction protocols. Wyd. 2. Totowa, N.J: Humana, 2008.
Znajdź pełny tekst źródłaTsai, Yueh-Lin. Function and Regulation of ALS/FTD-associated RNA Binding Protein FUS. [New York, N.Y.?]: [publisher not identified], 2021.
Znajdź pełny tekst źródłaTravers, A. A. DNA-protein interactions. London: Chapman & Hall, 1993.
Znajdź pełny tekst źródłaSandberg, Kathryn, i Susan E. Mulroney, red. RNA Binding Proteins. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-6446-8.
Pełny tekst źródłaLehrer, Helaina. Investigating the role of the RNA binding protein TDP-43 in Amyotrophic Lateral Sclerosis using animal and cell-based models of disease. [New York, N.Y.?]: [publisher not identified], 2015.
Znajdź pełny tekst źródłaYeo, Gene W., red. Systems Biology of RNA Binding Proteins. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1221-6.
Pełny tekst źródłaB, Denman Robert, red. RNA binding proteins in development and disease. Trivandrum: Research Signpost, 2008.
Znajdź pełny tekst źródłaSteitz, Thomas A. Structural studies of protein-nucleic acid interaction: Thesources of sequence-specific binding. Cambridge: Cambridge University Press, 1993.
Znajdź pełny tekst źródłaCzęści książek na temat "RNA-binding protein"
Penalva, Luiz O. F. "RNA-binding Protein". W Encyclopedia of Systems Biology, 1875–76. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_313.
Pełny tekst źródłaReboll, Marc R. "Mapping of Protein Binding RNA Elements". W RNA Mapping, 187–94. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1062-5_16.
Pełny tekst źródłaGoodwin, Marianne, i Maurice S. Swanson. "RNA-Binding Protein Misregulation in Microsatellite Expansion Disorders". W Systems Biology of RNA Binding Proteins, 353–88. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1221-6_10.
Pełny tekst źródłaMatia-González, Ana M., i André P. Gerber. "Approaches for Dissecting RNA-Binding Protein Networks". W Fungal RNA Biology, 347–70. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05687-6_14.
Pełny tekst źródłaSharma, Shalini. "Isolation of a Sequence-Specific RNA Binding Protein, Polypyrimidine Tract Binding Protein, Using RNA Affinity Chromatography". W Methods in Molecular Biology, 1–8. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-475-3_1.
Pełny tekst źródłaBell, Thomas J., i James Eberwine. "Live Cell Genomics: RNA Exon-Specific RNA-Binding Protein Isolation". W Methods in Molecular Biology, 457–68. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2806-4_31.
Pełny tekst źródłaLiu, Zhi-Ping, i Luonan Chen. "Prediction of RNA Binding Sites in Proteins". W Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics, 153–70. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118567869.ch8.
Pełny tekst źródłaJain, Ritu, Tiffany Devine, Ajish D. George, Sridar V. Chittur, Timothy E. Baroni, Luiz O. Penalva i Scott A. Tenenbaum. "RIP-Chip Analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling". W RNA, 247–63. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-59745-248-9_17.
Pełny tekst źródłaCalnan, Barbara J., Sara Biancalana, Bruce Tidor, Derek Hudson i Alan D. Frankel. "RNA binding by the HIV-1 Tat protein". W Peptides, 685–87. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_273.
Pełny tekst źródłaKöster, Tino, i Dorothee Staiger. "RNA-Binding Protein Immunoprecipitation and High-Throughput Sequencing". W Methods in Molecular Biology, 453–61. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0880-7_23.
Pełny tekst źródłaStreszczenia konferencji na temat "RNA-binding protein"
Adamek, Maksimiljan. "Molecular Grammar of RNA-binding Protein Interactions in Formation and Function of Ribonucleoprotein Complexes". W Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.ii15.
Pełny tekst źródłaKralj, Sebastjan, Milan Hodošček, Marko Jukić i Urban Bren. "A comprehensive in silico protocol for fast automated mutagenesis and binding affinity scoring of protein-ligand complexes". W 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.674k.
Pełny tekst źródłaSankar, Kannan, Rasna R. Walia, Carla M. Mann, Robert L. Jernigan, Vasant G. Honavar i Drena Dobbs. "An analysis of conformational changes upon RNA-protein binding". W BCB '14: ACM-BCB '14. New York, NY, USA: ACM, 2014. http://dx.doi.org/10.1145/2649387.2660790.
Pełny tekst źródłaNieves, Bethsaida I., Shuang Niu, Dedeepya Vaka, Julia Salzman, Patrick Brown i Alejandro I. Sweet-Cordero. "Abstract 204: Molecular function of the RNA binding protein EWS in RNA processing". W Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-204.
Pełny tekst źródłaKim, Hyun Min, Mi Jin Jeon, Seo Young Park, Sang Hoon Ma i Young Hee Joung. "Functional Characterization of RNA-Binding Protein Isolated from Hot Pepper". W The 3rd World Congress on New Technologies. Avestia Publishing, 2017. http://dx.doi.org/10.11159/icbb17.123.
Pełny tekst źródłaAngeles, Christina V., Markus Hafner, Nicholas D. Socci, Penelope DeCarolis, Thomas Tuschl i Samuel Singer. "Abstract 3100: The RNA-binding protein insulin-like growth factor 2 mRNA-binding protein 3 is oncogenic in liposarcoma". W Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3100.
Pełny tekst źródłaLan, Lan, Hao Liu, Amber Smith, Carl Appelman, Jia Yu, Sarah Larsen, Rebecca Marquez i in. "Abstract 4817: Molecular cancer therapy targeting RNA-binding protein Musashi-1". W Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4817.
Pełny tekst źródłaLiu, Zhi-Ping. "Systematic identification of local structure binding motifs in protein-RNA recognition". W 2014 8th International Conference on Systems Biology (ISB). IEEE, 2014. http://dx.doi.org/10.1109/isb.2014.6990735.
Pełny tekst źródłaShen, Luhan, Chengxin He, Haiying Wang, Yuening Qu i Lei Duan. "DARE: Sequence-Structure Dual-Aware Encoder for RNA-Protein Binding Prediction". W 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2023. http://dx.doi.org/10.1109/bibm58861.2023.10385694.
Pełny tekst źródłaGomer, R. H., W. Chen i D. Pilling. "Inhibiting a RNA Motif Binding Protein Attenuates Pulmonary Fibrosis in Mice". W American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4707.
Pełny tekst źródłaRaporty organizacyjne na temat "RNA-binding protein"
Gafni, Yedidya, i Vitaly Citovsky. Inactivation of SGS3 as Molecular Basis for RNA Silencing Suppression by TYLCV V2. United States Department of Agriculture, listopad 2013. http://dx.doi.org/10.32747/2013.7593402.bard.
Pełny tekst źródłaLiao, Jianhua, Jingting Liu, Baoqing Liu, Chunyan Meng i Peiwen Yuan. Effect of OIP5-AS1 on clinicopathological characteristics and prognosis of cancer patients: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, październik 2022. http://dx.doi.org/10.37766/inplasy2022.10.0118.
Pełny tekst źródłaMorrison, Mark, i Joshuah Miron. Molecular-Based Analysis of Cellulose Binding Proteins Involved with Adherence to Cellulose by Ruminococcus albus. United States Department of Agriculture, listopad 2000. http://dx.doi.org/10.32747/2000.7695844.bard.
Pełny tekst źródłaWhitham, Steven A., Amit Gal-On i Tzahi Arazi. Functional analysis of virus and host components that mediate potyvirus-induced diseases. United States Department of Agriculture, marzec 2008. http://dx.doi.org/10.32747/2008.7591732.bard.
Pełny tekst źródłaWhitham, Steven A., Amit Gal-On i Victor Gaba. Post-transcriptional Regulation of Host Genes Involved with Symptom Expression in Potyviral Infections. United States Department of Agriculture, czerwiec 2012. http://dx.doi.org/10.32747/2012.7593391.bard.
Pełny tekst źródłaMawassi, Munir, i Valerian Dolja. Role of RNA Silencing Suppression in the Pathogenicity and Host Specificity of the Grapevine Virus A. United States Department of Agriculture, styczeń 2010. http://dx.doi.org/10.32747/2010.7592114.bard.
Pełny tekst źródłaPorat, Ron, Gregory T. McCollum, Amnon Lers i Charles L. Guy. Identification and characterization of genes involved in the acquisition of chilling tolerance in citrus fruit. United States Department of Agriculture, grudzień 2007. http://dx.doi.org/10.32747/2007.7587727.bard.
Pełny tekst źródłaAtasoy, Ulus, J. W. Davis i Tim Hoffman. RNA Binding Proteins Posttranscriptionally Regulate Genes Involved In Oncogenesis. Fort Belvoir, VA: Defense Technical Information Center, czerwiec 2010. http://dx.doi.org/10.21236/ada540837.
Pełny tekst źródłaEpel, Bernard, i Roger Beachy. Mechanisms of intra- and intercellular targeting and movement of tobacco mosaic virus. United States Department of Agriculture, listopad 2005. http://dx.doi.org/10.32747/2005.7695874.bard.
Pełny tekst źródłaGrumet, Rebecca, i Benjamin Raccah. Identification of Potyviral Domains Controlling Systemic Infection, Host Range and Aphid Transmission. United States Department of Agriculture, lipiec 2000. http://dx.doi.org/10.32747/2000.7695842.bard.
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