Rozprawy doktorskie na temat „Radiotherapy and Nuclear Medicine”
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COSTA, ALESSANDRO M. da. "Metodos de calibracao e de intercomparacao de calibradores de dose utilizados em servicos de medicina nuclear". reponame:Repositório Institucional do IPEN, 1999. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10713.
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Dissertacao (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
Massicano, Felipe. "Modelagem de um sistema de planejamento em radioterapia e medicina nuclear com o uso do código MCNP6". Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/85/85133/tde-11032016-093447/.
Pełny tekst źródłaCancer therapy has many branches and one of them is the use of radiation sources as treatment leading method. Radiotherapy and nuclear medicine are examples of these treatment types. For using the ionization radiation as main tool for the therapy, there is the need of crafting many treatment simulation in order to maximum the tumoral tissue dose without throught the dose limit in health tissue surrounding. Treatment planning systems (TPS) are systems which have the purpose of simulating these therapy types. Nuclear medicine and radiotherapy have many distinct features linked to the therapy mode and consequently they have different TPS destined for each. The radiotherapy TPS is more developed than the nuclear medicine TPS and by that reason the development of a TPS that was similar to the radiotherapy TPS, but enough generic for include other therapy types, it will contribute with significant advances in nuclear medicine and in others therapy types with radiation. Based on this, the goal of work was to model a TPS that utilizes the Monte Carlo N-Particle Transport code (MCNP6) in order to simulate radiotherapy therapy, nuclear medicine therapy and with potential for simulating other therapy types too. The result of this work was the creation of a Framework in Java language, objectoriented, named IBMC which will assist in the development of new TPS with MCNP6 code. The IBMC allowed to develop rapidly and easily TPS for radiotherapy and nuclear medicine and the results were validated with systems already consolidated. The IBMC showed high potential for developing TPS by new therapy types.
Adjeiwaah, Mary. "Quality assurance for magnetic resonance imaging (MRI) in radiotherapy". Licentiate thesis, Umeå universitet, Institutionen för strålningsvetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-142603.
Pełny tekst źródłaMASSICANO, FELIPE. "Modelagem de um sistema de planejamento em radioterapia e medicina nuclear com o uso do código MCNP6". reponame:Repositório Institucional do IPEN, 2015. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26371.
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Tese (Doutorado em Tecnologia Nuclear)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
Shortkroff, Sonya. "The influence of radionuclides on synovitis and its assessment by MRI". Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326039.
Pełny tekst źródłaCOSTA, ALESSANDRO M. da. "Desenvolvimento de camaras de ionizacao Tandem para utilizacao em programas de controle da qualidade em radioterapia e radiodiagnostico". reponame:Repositório Institucional do IPEN, 2003. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11103.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Tese (Doutoramento)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
FAPESP:98/14763-4
Vouche, Michael. "Radiation Segmentectomy, Radiation Lobectomy and Response Assessment after 90Yttrium Radioembolization for Hepatocellular carcinoma: Imaging and Clinical Implications". Doctoral thesis, Universite Libre de Bruxelles, 2017. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/241979.
Pełny tekst źródłaDoctorat en Sciences médicales (Médecine)
info:eu-repo/semantics/nonPublished
Costa, Gustavo. "IRDose : un outil web de dosimétrie individualisée basé sur la méthode Monte Carlo pour les patients en thérapie avec le 177Lu". Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30027.
Pełny tekst źródłaNuclear medicine is a medical specialty that uses a radiopharmaceutical whose administration generally allows to visualize an organ function by detecting the gamma (γ) emissions of the targeted radioisotope. When the goal of this practice is molecular radiotherapy, isotopes emitting short-range radiation (α, β or electron Augers) are preferred. In general, treatments using 177Lu-DOTATATE still uses the historical practice of a fixed administration of 7.4 GBq per cycle, regardless the sex, age or inter-patient fixation variability. This causes a large fluctuation of the absorbed dose delivered to organs at risk and tumour targets, and therefore a great difficulty in predicting the treatment results. Recent studies suggest that treatment planning based on individual dosimetry is a way to optimize the treatment. The objective of this work is to contribute to the development of clinical dosimetry in molecular radiotherapy, in particular by developing a web tool based on the Monte Carlo method GATE dedicated to individualised internal dosimetry of patients treated with 177Lu. First of all, a study on the modelling of the SPECT systems by the Monte Carlo toolkit, GATE was realized, as well as the optimization of these simulations, where different methods were used in order to reduce simulation time. These techniques reduced simulation time by up to 85, and some of them were used in the comparison between simulated and experimental tomographic acquisitions. This comparison allowed the modelling of an experimental context which was used for the web tool validation. Finally, the web page was designed using the Django framework where a sequence of scripts in Python and Bash perform the calculation of the absorbed dose by GATE simulations. The absorbed doses obtained were compared with OLINDA versions 1 and 2, and the results show differences between 0.3% and 6.1%, depending on OLINDA's version
MARTINS, ELAINE W. "Desenvolvimento e aplicação de um simulador pediátrico craniano para dosimetria em tomografia computadorizada". reponame:Repositório Institucional do IPEN, 2016. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26608.
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Para avaliar os níveis de exposição e a dose absorvida em pacientes submetidos a exames de tomografia computadorizada, TC, é necessário calcular os índices de dose em medições com um simulador de PMMA, ou cheio de água. O simulador deve ser capaz de reproduzir as características de absorção e espalhamento do corpo ou parte do corpo humano em um campo de radiação. As grandezas específicas em TC: índice de kerma livre no ar (Ca,100), índice de kerma no ar ponderado (CW), índice de kerma no volume total (Cvol) e produto kerma no ar-comprimento (PKL) devem ser determinadas e comparadas com os níveis de referência já existentes na literatura. Neste trabalho foi desenvolvido um simulador pediátrico craniano, já que no Brasil os níveis de referência para diagnósticos (NRDs) disponíveis foram determinados baseados em um simulador padrão adulto. O simulador desenvolvido inovou em sua construção apresentando materiais que simulam a calota craniana em osso cortical (alumínio) e osso esponjoso (PVC). O seu interior foi preenchido com água destilada. As dimensões foram escolhidas de acordo com as recomendações da Organização Mundial da Saúde e do International Commission on Radiation Units, para o tamanho da cabeça de uma criança de 0 a 5 anos: 160 mm de diâmetro e 155 mm de altura. A calota craniana tem uma espessura de 4 mm e diâmetro interno de 111,9 mm. Para avaliar seu comportamento foram realizados testes em laboratórios e em feixes clínicos. Os resultados apresentaram uma atenuação de até 23% na utilização dos materiais que simulam a calota craniana evidenciando que os valores adotados para os cálculos de NRD podem estar superestimando a dose recebida por pacientes pediátricos. Percebe-se que a dose recebida em exames de crânio apresenta uma distribuição diferente por ser parcialmente atenuada e/ou retroespalhada pela calota craniana, o que não é considerado ao se utilizar o simulador constituído apenas de PMMA.
Tese (Doutorado em Tecnologia Nuclear)
IPEN/T
Instituto de Pesquisas Energéticas e Nucleares - IPEN-CNEN/SP
Sjögren, Adam. "The impact of metallic cranial implants on proton-beam radiotherapy treatment plans for near implant located tumours : A phantom study on the physical effects and agreement between simulated treatment plans and the resulting treatment for near implant located cranial tumours". Thesis, Umeå universitet, Institutionen för fysik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-149530.
Pełny tekst źródłaMairs, Robert J. "Targeted radiotherapy of cancer". Thesis, University of Glasgow, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248190.
Pełny tekst źródłaMurphy, Caroline Claire Scanlon. "A history of radiotherapy to 1950 : cancer and radiotherapy in Britain 1850-1950". Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278710.
Pełny tekst źródłaMillin, Anthony. "Verification of stereotactic radiotherapy". Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/12287/.
Pełny tekst źródłaScaife, Lucy. "Proteomic identification of putative biomarkers of radiotherapy resistance". Thesis, University of Hull, 2012. http://hydra.hull.ac.uk/resources/hull:6870.
Pełny tekst źródłaBook, Lynn Novella. "Surface imaging for patient setup and monitoring for breast radiotherapy". Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/41311.
Pełny tekst źródłaIncludes bibliographical references (p. 66-67).
Approximately one in eight women will get breast cancer at some point in their lives. A promising new treatment is partial breast irradiation, in which multiple radiation beams cross at the tumor site within the patient. This method of radiotherapy treats only a portion of the breast for a relatively small number of treatments with a high dose per treatment. This method requires much higher accuracy of patient alignment as the tumor site must be correct targeted. This study examined the possibility of using the VisionRT (London, UK) software and cameras for surface visualization to align patients for this treatment. A portable, single pod, the "Mini Cam" was found to be able to generate images for translations less than 2.5-5.5 cm, depending on the direction of translation. Calibration was a key aspect to ensuring accurate results. Eight patients were studied for deformation, breathing motion and day to day alignment. Surface images were taken at several points during regular treatment. Deformation was found to be small and never exceeded and average value of 2 mm. No correlation was found between the amount of deformation and the breast size or planning treatment volume. The average peak-to-peak breathing motion was 0.99-2.16 mm. Variability was discovered in the gating function of the VisionRT software. Aligning patients based on the first treatment session was found to be more accurate than aligning to a CT image taken weeks earlier.
by Lynn Novella Book.
S.M.
Davidson, Susan Elizabeth. "Potential prognostic indicators for the radiotherapy of cervical carcinoma". Thesis, University College London (University of London), 1991. http://discovery.ucl.ac.uk/1348985/.
Pełny tekst źródłaObeidat, Mohammad Ali. "Radiotherapy Measurements with a Deoxyribonucleic Acid Doublestrand-Break Dosimeter". Thesis, The University of Texas Health Science Center at San Antonio, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10281552.
Pełny tekst źródłaMany types of dosimeters are used in the clinic to measure radiation dose for therapy but none of them directly measures the biological effect of this dose. The overall purpose of this work was to develop a dosimeter that measures biological damage in the form of double-strand breaks to deoxyribonucleic acid. This dosimeter could provide a more biologically relevant measure of radiation damage than the currently utilized dosimeters. A pair of oligonucleotides was designed to fabricate this dosimeter. One is labeled with a 5’-end biotin and the other with a 5’-end 6 Fluorescein amidite (fluorescent dye excited at 495?nanometer, with a peak emission at 520 nanometer). These were designed to adhere to certain locations on the pRS316 vector and serve as the primers for polymerase chain reactions. The end product of this reaction is a 4 kilo-base pair double strands deoxyribonucleic acid fragment with biotin on one end and 6 Fluorescein amidite oligonucleotide on the other attached to streptavidin beads. The biotin end connects the double strands deoxyribonucleic acid to the streptavidin bead. These bead-connected double strands deoxyribonucleic acid were suspended in 50 microliter of phosphate-buffered saline and placed into a tube for irradiation. Following irradiation of the deoxyribonucleic acid dosimeter, we take advantage of the magnetic properties of the streptavidin bead by placing our sample microtube against a magnet. The magnetic field pulls the streptavidin beads against the side of the tube. If a double-strand-break has occurred for a double strands deoxyribonucleic acid, the fluorescein end of the double strands deoxyribonucleic acid becomes free and is no longer attached to the bead or held against the side of the microtube. The free fluorescein following a double-strand-break in double strands deoxyribonucleic acid is referred to here as supernatant. The supernatant is extracted and placed in another microtube, while the unbroken double strands deoxyribonucleic acid remain attached to the beads and stay in the microtube (Fig. 4). Those beads were re-suspended with 50 microliter of phosphate-buffered saline again (called beads), then we placed both supernatant and beads in a reader microplate and we read the fluorescence signal for both with a fluorescence reader (BioTek Synergy 2). These beads and supernatant fluorescence signals are denoted by B and S, respectively. The relative amount of supernatant fluorescence counts is proportional to the probability of a double-strand-break. The probability of double-strand-break was calculated with the following equation:
(S-BG)/(S+B-2BG) (1)
where S was the supernatant fluorescence intensity (related to the number of double strands deoxyribonucleic acid with double-strand breaks), B was the re-suspended beads fluorescence intensity (related to the number of double strands deoxyribonucleic acid without double-strand breaks), and BG was the phosphate-buffered saline fluorescence intensity (related to the background signal). There are two advantages that this type of dosimeter has over the gel separation technique. First, it is important to irradiate deoxyribonucleic acid in a solution that has similar osmolarity and ion concentrations to that in a human, such as phosphate-buffered saline. A gel dosimeter would require a transfer to gel to separate deoxyribonucleic acid, whereas our dosimeter can be separated in this solution. Currently, we use pipettes to manually perform this separation, but this step could be automated. Second, the magnetic deoxyribonucleic acid separation technique is much faster than that for gel electrophoresis. Calibration of radiotherapy equipment isn’t something that happens in national science laboratories, with only world-leading experts. This is something that happens locally at every cancer clinic, with physicists that do not have the luxury of focusing solely on this one measurement. For this reason, ease of use is critical for this type of technology. (Abstract shortened by ProQuest.)
Cufflin, Rebecca Sian. "Verification of Intensity Modulated Radiotherapy". Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/25873/.
Pełny tekst źródłaSooriyajeevan, M. J. S. J. "Image filtering in nuclear medicine". Thesis, University of Aberdeen, 1996. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU090122.
Pełny tekst źródłaWang, Silas Lancelot. "Clinical characteristics and treatment response to radiotherapy of optic nerve sheath meningiomas". [New Haven, Conn. : s.n.], 2007. http://ymtdl.med.yale.edu/theses/available/etd-08282007-150948/.
Pełny tekst źródłaSöderlund, Leifler Karin. "DNA repair pathways and the effect of radiotherapy in breast cancer". Doctoral thesis, Linköpings universitet, Onkologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17955.
Pełny tekst źródłaMehmood, Sajid. "Identification of predictive biomarkers of resistance to radiotherapy in rectal cancer". Thesis, University of Hull, 2013. http://hydra.hull.ac.uk/resources/hull:10110.
Pełny tekst źródłaKhoo, Vincent. "A study of conformal radiotherapy methods for brain and prostate cancer". Thesis, Institute of Cancer Research (University Of London), 2000. http://publications.icr.ac.uk/9718/.
Pełny tekst źródłaFarajollahi, Ali Reza. "An investigation into the applications of polymer gel dosimetry in radiotherapy". Thesis, Online version, 1998. http://ethos.bl.uk/OrderDetails.do?did=1&uin=uk.bl.ethos.284699.
Pełny tekst źródłaZhou, Tingyang. "Redox Mechanisms in Radiotherapy and Hypoxic Preconditioning". The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1469019913.
Pełny tekst źródłaMishra, Nishikant. "A novel case-based reasoning approach to radiotherapy dose planning". Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/29347/.
Pełny tekst źródłaDavies, Elizabeth. "The quality of survival of patients with malignant cerebal glioma following radiotherapy". Thesis, Queen Mary, University of London, 1998. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1664.
Pełny tekst źródłaParker, Alexandra. "Risk stratification in rectal cancer : identifying tumours resistant to pre-operative radiotherapy". Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/3157.
Pełny tekst źródłaJammal, Ghada. "Multiscale image restoration in nuclear medicine". Phd thesis, [S.l.] : [s.n.], 2001. http://elib.tu-darmstadt.de/diss/000100/GJammal.pdf.
Pełny tekst źródłaDarwesh, Reem. "Motion correction in nuclear medicine imaging". Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664310.
Pełny tekst źródłaJose, Romina Marie Johnston. "Analysis of renal nuclear medicine images". Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342249.
Pełny tekst źródłaWhalley, D. R. "Image processing techniques in nuclear medicine". Thesis, Open University, 1989. http://oro.open.ac.uk/57292/.
Pełny tekst źródłaGardner, Joseph. "EPID-based Dose Verification for Adaptive Radiotherapy". VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2941.
Pełny tekst źródłaRoyle, Georgina. "Towards quantitative intra-nuclear dose mapping of auger emitting radionuclides used for targeted radiotherapy". Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:83c94d40-91a2-4175-b208-b5ea1bd5a207.
Pełny tekst źródłaElFadl, Dalia. "Proteomic identification and validation of biomarkers associated with resistance to radiotherapy in breast cancer". Thesis, University of Hull, 2012. http://hydra.hull.ac.uk/resources/hull:13996.
Pełny tekst źródłaRoussakis, Yiannis G. "Strategies for adaptive radiotherapy : towards clinically efficient workflows". Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6611/.
Pełny tekst źródłaPAIVA, FABIO de. "Estudo das respostas de TLD tipo LiF para caracterização de campos mistos". reponame:Repositório Institucional do IPEN, 2016. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26930.
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A Terapia por Captura de Nêutrons, NCT (Neutron Capture Therapy) é uma técnica radioterápica em que a energia útil do tratamento vem da energia liberada em uma reação nuclear e não do feixe primário, como comumente utilizado em outros procedimentos radioterápicos. O Boro, por constituir-se em um elemento de baixa toxicidade e por apresentar um isótopo (10B) com alta seção de choque para a reação 10B(n,α)7Li tem sido o elemento mais utilizado nas pesquisas que visam o aprimoramento e a promoção desta técnica, derivando daí o termo BNCT (Boron Neutron Capture Therapy). Para fins de pesquisa em BNCT foi construída ao longo de um dos extratores de feixes (BH - Beam Hole) do reator IEA-R1 uma instalação, onde filtros e moderadores são posicionados entre o núcleo do reator e a posição de irradiação com o objetivo de modular o feixe de irradiação, otimizando a componente útil do feixe, os nêutrons térmicos, e reduzindo os contaminantes, raios gama e nêutrons em outras faixas energéticas. Tem-se realizado estudos visando a implementação de melhorias na caracterização e otimização do feixe obtido nesse arranjo instalado no BH-3. Atualmente a monitoração dos nêutrons é feita através de folhas de ativação, e a componente gama pelo TLD-400. Uma nova metodologia de monitoração tem sido estudada pelo grupo. A referida técnica consiste em usar TLDs de tipos diferentes, ou seja, que possuam sensibilidades distintas aos nêutrons térmicos, em virtude de diferenças na concentração dos isótopos de Lítio. No estudo dessa nova metodologia têm sido usados os TLD-600 e TLD-700. Este trabalho propõe uma metodologia usando o par TLD-100 e TLD-700. Inicialmente foi verificada a reprodutibilidade das respostas dos TLDs 700, 400 e 100 frente a campos gama puro e campos mistos, gama e nêutron. Campos estes obtidos em arranjos usando fontes de 60Co e 241AmBe. A partir de simulações usando o VI MCNP5 foi projetado e construído um Irradiador de campos mistos, que permitiu expor os dosímetros em campos mistos com diferentes espectros energéticos. As condições criadas no irradiador permitiram verificar, como a resposta do TLD é modificada pelas mudanças no espectro energético de um campo misto gama e nêutrons de baixo fluxo. O irradiador de campo misto permitiu condições para estabelecer uma relação entre o formato da curva termoluminescente e a composição do campo misto. A relação estabelecida relaciona o fluxo relativo e a razão entre a resposta das duas regiões de interesse dos TLDs 700 e 100. A partir de campos mistos com condições controladas, esse trabalho permitiu verificar a viabilidade do uso do par de TLD-100 e TLD-700 para monitoração de nêutrons térmicos na instalação de BNCT.
Dissertação (Mestrado em Tecnologia Nuclear)
IPEN/D
Instituto de Pesquisas Energéticas e Nucleares - IPEN-CNEN/SP
Valastyán, Iván. "Applications of tomographic imaging in nuclear medicine". Licentiate thesis, KTH, Physics, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4187.
Pełny tekst źródłaValastyán, Iván. "Applications of tomographic imaging in nuclear medicine /". Stockholm : School of engineering sciences, Royal Institute of Technology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4187.
Pełny tekst źródłaEskin, Joshua Daniel 1960. "Semiconductor gamma-ray detectors for nuclear medicine". Diss., The University of Arizona, 1997. http://hdl.handle.net/10150/288740.
Pełny tekst źródłaOliveira, V. A. "Maximum entropy image restoration in nuclear medicine". Thesis, University of Southampton, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235282.
Pełny tekst źródłaHanvey, Scott Lewis. "Magnetic resonance imaging to improve structural localisation in radiotherapy planning". Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/5117/.
Pełny tekst źródłaCarr, Simon David. "Assessing the effects of radiotherapy on head and neck squamous cell carcinoma using microfluidic techniques". Thesis, University of Hull, 2013. http://hydra.hull.ac.uk/resources/hull:8396.
Pełny tekst źródłaCoetzee, Nicolene. "A phantom based evaluation on the effects of patient breathing motion on Stereotactic Body Radiotherapy treatment volumes". Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32181.
Pełny tekst źródłaAguwa, Kasarachi. "Radiation Dose Study in Nuclear Medicine Using GATE". Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/593601.
Pełny tekst źródłaHarvey, Darren Keith. "Design of a Compton camera for nuclear medicine". Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284644.
Pełny tekst źródłaTeles, Patricia Rebello. "Hadronterapia: abordagem semiclássica da perda de energia, efeitos da fragmentação nuclear e taxa de reação". Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-27112014-081805/.
Pełny tekst źródłaThe aim of radiation therapy is to deliver the dose as high and as uniform as possible to diseased tissue sparing all the other parts, that is healthy and critical tissues, without causing unwanted and unnecessary side effects for the patient. Difficults to achieve this goal start with the determination of the three dimensional volumes of interest and end up in realizing a three-dimensional uniform and maximal as possible, the dose distribution. The technique of intensity-modulated radiotherapy (IMRT) as form of conformation in conventional radiation therapy is a real revolution. On the other hand, the use of therapeutic charged particles, as protons and carbon íons, is the technology of the actual future which is really the challenge in conformation of dose to targets, thanks to energy deposition characteristics of hadronic beams. The aim of this work is to review the basic physics concerning the treatment of localized tumors with charged particles by applying a semi-classical approach to obtain a dispersion in the equation of energy loss, originally derived by Hans Bethe and Felix Bloch. On a second moment we use statistical methods (Goldhaber statistic model) to estimate the energy of fragment after nuclear fragmentation processes and, in addition, we obtain a expression for the nuclear reaction rate to introduce how the temperature on tumor region would affect it.
Enblom, Anna. "Nausea and vomiting in patients receiving acupuncture, sham acupuncture or standard care during radiotherapy". Doctoral thesis, Linköpings universitet, Omvårdnad, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17237.
Pełny tekst źródłaWidita, Rena Physics Faculty of Science UNSW. "Simultaneous optimization of beam positions for treatment planning and for image reconstruction in radiotherapy". Awarded by:University of New South Wales. School of Physics, 2006. http://handle.unsw.edu.au/1959.4/25774.
Pełny tekst źródłaNguyen, Son Hung 1966. "Topographic classification of nuclear medicine images for tumor detection". Thesis, The University of Arizona, 1992. http://hdl.handle.net/10150/278117.
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