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Artykuły w czasopismach na temat "Quantitative Inheritance"
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LAGERVALL, P. MATS. "QUANTITATIVE INHERITANCE AND DOMINANCE". Hereditas 46, nr 3-4 (9.07.2010): 481–96. http://dx.doi.org/10.1111/j.1601-5223.1960.tb03095.x.
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LAGERVALL, P. MATS. "QUANTITATIVE INHERITANCE AND DOMINANCE". Hereditas 47, nr 2 (2.09.2009): 197–202. http://dx.doi.org/10.1111/j.1601-5223.1961.tb01770.x.
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LAGERVALL, P. MATS. "QUANTITATIVE INHERITANCE AND DOMINANCE". Hereditas 47, nr 1 (2.09.2009): 111–30. http://dx.doi.org/10.1111/j.1601-5223.1961.tb01862.x.
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LAGERVALL, P. MATS. "QUANTITATIVE INHERITANCE AND DOMINANCE". Hereditas 47, nr 1 (2.09.2009): 131–59. http://dx.doi.org/10.1111/j.1601-5223.1961.tb01863.x.
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LAGERVALL, P. MATS. "QUANTITATIVE INHERITANCE AND DOMINANCE". Hereditas 49, nr 1-2 (2.09.2009): 167–84. http://dx.doi.org/10.1111/j.1601-5223.1963.tb01873.x.
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Coman, M. S., i A. N. Popescu. "INHERITANCE OF SOME STRAWBERRY QUANTITATIVE TRAITS". Acta Horticulturae, nr 439 (wrzesień 1997): 81–88. http://dx.doi.org/10.17660/actahortic.1997.439.7.
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WEXELSEN, H. "QUANTITATIVE INHERITANCE AND LINKAGE IN BARLEY". Hereditas 18, nr 3 (9.07.2010): 307–48. http://dx.doi.org/10.1111/j.1601-5223.1934.tb02618.x.
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Hofmanová, B., L. Vostrý, I. Majzlík i H. Vostrá-Vydrová. "Characterization of greying, melanoma, and vitiligo quantitative inheritance in Old Kladruber horses". Czech Journal of Animal Science 60, No. 10 (15.07.2016): 443–51. http://dx.doi.org/10.17221/8524-cjas.
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Novoselovic, D., Marijana Baric, G. Drezner, J. Gunjaca i A. Lalic. "Quantitative inheritance of some wheat plant traits". Genetics and Molecular Biology 27, nr 1 (2004): 92–98. http://dx.doi.org/10.1590/s1415-47572004000100015.
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Khalipsky, Anatoly N., Andrey A. Churakov, Natalia M. Popova i Olga A. Rozhanskaya. "QUANTITATIVE TRAITS INHERITANCE IN HYBRID POTATO POPULATIONS". Bulletin of KSAU, nr 11 (2021): 93–99. http://dx.doi.org/10.36718/1819-4036-2021-11-93-99.
Pełny tekst źródłaRozprawy doktorskie na temat "Quantitative Inheritance"
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Roberts, Robert Caradog. "Studies in quantitative inheritance and their implications for animal breeding". Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/14300.
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Maniatis, Nikolaos. "Quantitative genetic analyses of growth traits in sheep under different models of inheritance". Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341920.
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Miyake, Takeshi. "STATISTICAL GENETIC EVALUATION OF ANIMALS FOR QUANTITATIVE TRAITS UNDER POLYGENIC MODEL AND MIXED INHERITANCE MODEL". Kyoto University, 1999. http://hdl.handle.net/2433/181392.
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Tashtemirov, Behzod. "Inheritance of Partial Resistance to White Mold in Field Pea (Pisum sativum L.)". Thesis, North Dakota State University, 2012. https://hdl.handle.net/10365/26387.
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Sclerotinia sclerotiorum causes white mold and severe yield losses of pea. 484 accessions from the Pisum core collection were screened for resistance using a mini-agar plug technique. 49, 41, and 13 accessions were identified with partial resistance based on lesion expansion inhibition (LEI), nodal transmission inhibition (NTI), and both traits combined, respectively. A genetic linkage map based on F2 DNA from the cross, Lifter/PI240515, was developed with 78 markers on 9 linkage groups (LG) spanning 734 cM. Two quantitative trait loci (QTL) were identified based on phenotypic data from F2:3 and F3:4 families. A single QTL on LGIII explained 34.1% of the phenotypic variation for LEI, while a second QTL on LGII(b) explained 2.5% of the phenotypic variation for NTI. This is the first report of QTL for S. sclerotiorum resistance in pea which will be useful in development of resistant pea varieties.
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Mustafa, A. M. "Quantitative inheritance of resistance to bacterial blight (Xanthomonas oryzae pv. oryzae) in some cultivars of rice". Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262082.
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Hallsson, Lára R. "Quantitative Trait Evolution in a Changing Environment in a Seed Beetle". Doctoral thesis, Uppsala universitet, Zooekologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-159284.
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During the last decades the climate has been changing more rapidly than in the preceding periods. This is for instance characterized by an increase in temperature. Interestingly, such changes in the environment are not necessarily constant over time as they often show high levels of fluctuation. Organisms are exposed to these changes and respond to them and a recent theoretical model predicts that fluctuations in the environment are important for populations’ response to climate change. The aim of this thesis is to investigate how populations respond to a changing environment, including fluctuations. My thesis is based on the previously mentioned theoretical model and I used a suite of laboratory experiments on the seed beetle Callsosobruchus maculatus, to test the model predictions in a quantitative genetic framework. First, I assessed the genetic architecture of several life history and morphological traits in order to verify that there is sufficient additive genetic variation for the population to respond to changes in the environment. Second, I tested the detailed model predictions explicitly, by investigating whether different types of environmental fluctuations matter for a population’s response. Third, I investigated changes in quantitative genetic variation after i) a rapid shift in temperature and ii) long term selection under increasing temperature including fluctuations. Fourth, I concentrated on sex differences in response to temperature, and finally, I assessed the relative importance of genetic and nongenetic inheritance for traits that differ in their plastic response to a change in the environment. I found that environmental fluctuations are highly important for a population’s response to environmental change. I could detect changes in a set of quantitative genetic parameters, suggesting that a population’s potential to respond to selection, environmental sensitivity and the evolution of phenotypic plasticity are affected by the selective past. I also found that sexes differ in additive genetic variation and plasticity and that parental effects may play an important role in the evolutionary process. Therefore, future studies would benefit greatly from considering details of the selective past and especially environmental fluctuations during attempts to predict how populations respond to a changing environment, particularly with regards to climate change.
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Narita, Akira. "A system for detection of multiple quantitative trait loci (QTL) under the mixed inheritance model in outbred populations". Kyoto University, 2004. http://hdl.handle.net/2433/147762.
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Kyoto University (京都大学)0048
新制・課程博士
博士(農学)
甲第10913号
農博第1419号
新制||農||891(附属図書館)
学位論文||H16||N3924(農学部図書室)
UT51-2004-G760
京都大学大学院農学研究科応用生物科学専攻
(主査)教授 佐々木 義之, 教授 守屋 和幸, 教授 広岡 博之
学位規則第4条第1項該当
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Mignerot, Laure. "Caractérisation cellulaire et génétique de la parthénogenèse chez l’algue brune Ectocarpus sp". Electronic Thesis or Diss., Sorbonne université, 2018. http://www.theses.fr/2018SORUS621.
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Bien que la reproduction sexuée soit prédominante chez les eucaryotes, plusieurs centaines d’organismes ont opéré une transition vers la reproduction asexuée. Les transitions entre reproduction sexuée et asexuée peuvent avoir une importance et des conséquences évolutives mais elles restent largement peu décrites au niveau écologique, moléculaire, génétique ou cytologique. La reproduction asexuée par parthénogenèse correspond au développement d’un organisme à partir de gamètes sans fécondation. Bien que beaucoup d’eucaryotes soient parthénogénétiques, nous connaissons très peu les bases génétiques, les causes et les conséquences évolutives conduisant à ce mode de reproduction asexuée. Les algues brunes sont un groupe d’eucaryotes multicellulaires qui présentent une incroyable diversité en termes de cycle de vie, de systèmes sexués ou mode de reproduction. Elles représentent d’excellents modèles pour étudier l’origine, l’évolution et les mécanismes de la parthénogenèse. Dans cette thèse, les nombreux outils génétiques et cellulaires développés pour l’algue brune modèle Ectocarpus ont permis de caractériser les loci impliqués dans la parthénogenèse et de mettre en lumière les causes et les conséquences de ce développement à l’échelle de l’organisme. Nos résultats soulignent le rôle clé des chromosomes sexuels en tant que régulateur majeur de la reproduction asexuée, ainsi que deux loci autosomaux. Des effets négatifs de la parthénogenèse sur la fitness des mâles ont été identifiés ainsi que des effets sur la fitness des générations du cycle de vie. Ces résultats indiquent que la parthénogenèse pourrait être à la fois sous sélection sexuelle et sous sélection antagoniste par rapport aux générations (polyploidallie) (Chapitre 2). La croissance des zygotes est significativement affectée par la capacité parthénogénétique des parents mâles et la transmission des mitochondries a été suivie afin de caractériser les retards de croissances observés (Chapitre 2 et 3). En parallèle, la transmission mitochondriale chez Ectocarpus sp.7 s’est révélé être non usuelle (Chapitre 3). Enfin, la carte génétique générée (Chapitre 2) pour l’espèce Ectocarpus siliculosus a été comparée à celle d’Ectocarpus sp.7 (génome de référence séquencé en 2010) et a révélé une synténie fortement conservé entre les deux espèces (Chapitre 4). En étudiant la parthénogenèse chez un organisme multicellulaire qui a évolué indépendamment des plantes et des animaux, ce travail a participé à approfondir les connaissances sur les mécanismes évolutifs conduisant à la parthénogenèseAlthough sexual reproduction predominates in eukaryotes, several hundred lineages have undergone the transition from sexuality to asexuality. Transitions between sexual and asexual reproduction are believed to have important evolutionary and ecological consequences, yet the molecular, genetic, and cytological foundations of such transitions remain elusive. One type of asexual reproduction is parthenogenesis, i.e., the development of an adult organism directly from gametes in the absence of fertilisation. Although many eukaryotes are capable of reproducing by parthenogenesis, we know very little about its genetic basis, and the evolutionary causes and consequences of transitions to asexuality are poorly understood. The brown algae are a group of multicellular eukaryotes, that show an extraordinary diversity of types of life cycle, sexual systems, modes of reproduction, and they provide excellent models to look at the origins, evolution and mechanisms underlying parthenogenesis. In this thesis, we have used a wide array of genomic and cell biology tools available for the model brown alga Ectocarpus to identify and characterize loci involved in parthenogenesis, shedding light on the causes and consequences of parthenogenesis at the organism level. Our results highlight the key role of the sex chromosome as a major regulator of asexual reproduction, together with two autosomal loci. Importantly, we identify several negative effects of parthenogenesis on male fitness, but also different fitness effects between parthenogenesis and life cycle generations, supporting the idea that parthenogenesis may be under both sexual selection and generation/ploidally-antagonistic selection (Chapter 2). Zygotic growth was significantly affected by the parthenogenetic capacity of the male parent and the putative role of mitochondrial inheritance patterns on the fitness of sporophytes was also investigated (Chapter 2 and 3). This work revealed an unusual transmission pattern of mitochondria specifically in Ectocarpus species 7 (Chapter 3). Finally, the QTL analysis (Chapter 2) required the construction of a genetic map for Ectocarpus siliculosus and a comparison with Ectocarpus species 7 genetic map (reference genome sequenced in 2010) showed that the synteny was highly conserved between the two species (Chapter 4). By investigating parthenogenesis in a multicellular organism that has independently evolved from plants and animals, the work presented in this thesis has helped to assess the diversity of evolutionary mechanisms that lead to parthenogenesis
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Taporoski, Tâmara Pessanha. "Herdabilidade das funções cognitivas em um estudo de coorte familiar: Projeto Corações de Baependi". Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-03072018-083447/.
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INTRODUÇÃO: Muitos são os fatores que contribuem para o desempenho cognitivo, porém o peso dos fatores genético, ambiental e sociodemográfico na composição das funções cognitivas ainda é pouco conhecido, especialmente em amostras brasileiras. Portanto, como o cálculo de herdabilidade estima a proporção da variância total do fenótipo atribuída ao fator genético, o presente trabalho avaliou a herdabilidade do desempenho em diferentes testes cognitivos em uma coorte de famílias com o propósito de melhor investigar os aspectos biológicos associados à performance cognitiva. MÉTODOS: Foram avaliados 1 717 indivíduos (60% mulheres, idades entre 18 e 91 anos e, 0 a 23 anos de escolarização), todos participantes do \'Projeto Corações de Baependi\'. Os domínios cognitivos foram avaliados por meio dos testes de lista de palavras (usando três escores diferentes), fluência verbal semântica - categoria animais (escores total e particionados por quartis de minuto) - e o teste de trilhas - parte B. As estimativas de herdabilidade, bem como o impacto de covariáveis sobre o desempenho nos testes, foram calculadas utilizando-se o modelo misto poligênico implementado no software SOLAR. RESULTADOS: Os valores de herdabilidade e respectivas covariáveis de influência significativa para os fenótipos (melhor modelo ajustado) foram os seguintes: teste de lista de palavras - escore total (h2= 0,30; idade, sexo e escolaridade), teste de lista de palavras - primeira evocação (h2= 0,22; idade, escolaridade, cronotipo e horário do dia) -, teste de fluência verbal (h2= 0,21; sexo, idade, escolaridade e horário do dia) - apresentando 4 quartis de minuto, o primeiro quartil (h2= 0,17; idade, escolaridade e horário do dia), o segundo quartil (h2= 0,09; escolaridade e horário do dia), o terceiro quartil (h2= 0,12; escolaridade e horário do dia) e o quarto quartil (h2= 0,0003; escolaridade e sexo) -, teste de lista de palavras - evocação tardia (h2= 0,28; idade e escolaridade) e teste de trilhas (h2= 0,42; sexo, idade e escolaridade). CONCLUSÕES: Os resultados indicaram que o teste de trilhas apresentou o componente genético mais alto de todos os testes e foi mais fortemente influenciado por idade. Testes de lista de palavras estimaram herdabilidades intermediárias e o teste de fluência verbal indicou a menor variância genética dentre os fenótipos e foi expressivamente impactado por escolaridade. O primeiro quartil de minuto do teste de fluência verbal apresentou maior componente herdável sugerindo que processos cognitivos automáticos são melhor explicados por componentes genéticos do que os demais. Efeitos de idade e escolaridade indicaram exercer influência significativa sobre todos os fenótipos e, por consequência, sobre o desempenho cognitivo de uma maneira geral. Maiores graus de escolaridade indicaram melhores performances e o avanço da idade indicou declínio no desempenho cognitivo. As estimativas do componente genético das funções cognitivas podem ser exploradas em estudos de associação genômica amplaINTRODUCTION: Many factors contribute to cognitive performance. The specific contribution of genetic, environmental or sociodemographic factors in the composition of cognitive functions is still unclear, especially in Brazilian samples. The calculation of heritability estimates the proportion of the total variance of the phenotype which is attributed to its genetic component. Thus, in order to better investigate the biological aspects associated to cognitive performance, this work assessed the heritability of performance in different cognitive tests in a family-based cohort. METHODS: 1,717 participants in the Baependi Heart Study were evaluated (60% women, ages between 18 and 91 years-old, 0 to 23 years of schooling). Cognitive domains were assessed using the words list test (immediate and delayed recall), semantic verbal fluency - category animals (total score and partitioned in quartiles of minute) and the trail making test - part B. The heritability estimates, as well as the impact of covariates over the performance, were calculate using the SOLAR software. RESULTS: The heritability values and the respective covariates of significant influence to the phenotypes (best-fit model) were as follows: Words list test (h2= 0,30; age and schooling), words list test - firs trial recall (h2= 0,22; age, schooling, chronotype and time of day), verbal fluency test (h2= 0,21; sex, age, schooling and time of day), quartiles of minute of the verbal fluency test - first quartile (h2= 0,17; age, schooling and time of day), second quartile (h2= 0,09; schooling and time of day), third quartile (h2= 0,12; schooling and time of day), fourth quartile (h2= 0,0003; schooling and sex), words list test - delayed recall (h2= 0,28; age and schooling and, trail making test (h2= 0,42; sex, age and, schooling). The results indicated that the trail making test - part B presented the highest genetic component of all tests and that it was strongly influenced by age. Words list tests showed intermediate heritability, and the verbal fluency test reflected the lowest heritability amongst the phenotypes, being markedly influenced by schooling. The first quartile of minute of the verbal fluency test presented the highest heritable component, suggesting that automatic cognitive processes are better explained by genetic component then the following ones. Effects of age and schooling influenced significantly all phenotypes and, as a consequence, cognitive performance as a whole. Higher education level was associated with better performances and advanced age with a decrease in cognitive performance. Our findings of genetic components for cognitive functions can be exploited in genome-wide association studies
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Khanal, Sarita. "Inheritance and Quantitative Trait Loci Analysis of Folate Content in Dry Beans". Thesis, 2012. http://hdl.handle.net/10214/3626.
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Dry beans (Phaseolus vulgaris L.) contain high levels of folates. These compounds are essential vitamins and folate deficiencies may lead to a number of health problems. The objectives of this study were to examine the mode of inheritance of folate content and identify quantitative trait loci (QTL) associated with folate content in dry beans. Inheritance of folate content was studied in the F1 hybrids of one-way diallel crosses among Othello, AC Elk, Redhawk and Taylor, and an F2 population of the cross between Redhawk and Othello. Total folate content and 5 methyltetrahydrofolate (5MTHF) were measured twice within a one hour interval. Significant variation in folate content was observed among the parental genotypes, their F1 hybrids, and the F2 individuals of a cross between Redhawk and Othello, ranging from 147 to 345 µg/100g. Reductions in the 5MTHF content and total folate content values in the second measurement from samples were highly variable for all four parental lines ranging from 5 to 30% and 7 to 33%, respectively. A single marker QTL analysis identified at least three QTL for folate content in the F2 population. For the majority of identified QTL, dominance effects appeared to be the major genetic effect.
Książki na temat "Quantitative Inheritance"
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Sriyoheswaran, S. Quantitative inheritance of some agronomic characters of three wide crosses of rice. Birmingham: University of Birmingham, 1995.
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Fahim, Mohammed. Quantitative inheritance of agronomic characters and comparison of different breeding methods in rice (Oryza sativa L.). Birmingham: University of Birmingham, 1995.
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Thompson, Aron. Human Quantitative Inheritance. University of Cambridge ESOL Examinations, 2000.
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Strier, Karen, R. A. Foley, Aron Thompson, C. G. Nicholas Mascie-Taylor i Nina Jablonski. Human Quantitative Inheritance. University of Cambridge ESOL Examinations, 2000.
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Correlated Inheritance of Quantitative and Qualitative Characters in Oats; 202. Creative Media Partners, LLC, 2021.
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Bahjat, Frances Rena. Characterization and genetic analysis of the resistance of nonobese diabetic mice to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and lethality. 2002.
Znajdź pełny tekst źródłaCzęści książek na temat "Quantitative Inheritance"
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Kowles, Richard. "Quantitative Inheritance". W Solving Problems in Genetics, 189–218. New York, NY: Springer New York, 2001. http://dx.doi.org/10.1007/978-1-4613-0205-6_6.
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Poehlman, John Milton. "Quantitative Inheritance in Plant Breeding". W Breeding Field Crops, 64–86. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-015-7271-2_4.
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Lipkin, Ehud, i Morris Soller. "Quantitative Trait Loci in Domestic Animals - Complex Inheritance Patterns". W Comparative Genomics, 123–51. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-4657-3_6.
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Xiong, Li-Yang, i Guo-An Tang. "Investigation of Loess Landform Inheritance by Using Quantitative Terrain Indexes". W Springer Geography, 135–68. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6404-4_5.
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Badu-Apraku, Baffour, M. A. B. Fakorede, A. O. Talabi, E. Obeng-Bio, S. G. N. Tchala i S. A. Oyekale. "Quantitative genetics, molecular techniques and agronomic performance of provitamin a maize in sub-Saharan Africa." W Quantitative genetics, genomics and plant breeding, 276–324. Wyd. 2. Wallingford: CABI, 2020. http://dx.doi.org/10.1079/9781789240214.0276.
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Abstract This chapter focuses on quantitative genetics, screening of germplasm collection at the International Institute of Tropical Agriculture, genetic diversity, genetic variation of provitamin A content in maize. Inheritance, heritability, genotype-by-environment for carotenoid content, population improvement, development of open-pollinated varieties were also discussed. Agronomic performance, stress tolerance, combining ability, heterosis were also conducted in sub-Saharan Africa. It may be concluded that maize in sub-Saharan Africa can be effectively subjected to genetic enhancement of provitamin A, along with other mineral components of the kernel and the plant traits for sustainable, high-quality food sufficiency to drastically reduce hunger and malnutrition.
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Schubiger, Franz Xaver, i B. Boller. "Inheritance of Crown Rust Resistance in a Perennial Ryegrass Genotype of the Cultivar Arvella". W Quantitative Traits Breeding for Multifunctional Grasslands and Turf, 249–53. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9044-4_34.
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Carson, S. D., i M. J. Carson. "Breeding for Durable Resistance to Red Band Needle Blight Caused by Dothistroma Pini Assuming Quantitative Inheritance". W Durability of Disease Resistance, 309. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2004-3_37.
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Fukui, Hideo. "Real Estate and the Legal System of Japan". W New Frontiers in Regional Science: Asian Perspectives, 3–7. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-8848-8_1.
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AbstractIn Part I, entitled Real Estate and the Legal System, we analyze owner-unknown land issues, land acquisitions, and real estate auctions.The use and value of real estate such as land and buildings are significantly affected by public laws and regulations related to urban planning and construction, the environment, and taxation; for example, contract laws such as the Act on Land and Building Leases; private laws regulating torts, collateral enforcement, and so on; tax laws that regulate transfer taxes, ownership taxes, and transaction taxes; and regulations surrounding land use and urban infrastructure development. This paper discusses, therefore, the relationships between these laws and real estate, identifies problems in the laws associated with real estate in Japan, and proposes improvements.First, in recent years, owner-unknown land issues have become a serious concern in Japan. The Japanese registry does not always reflect the actual rightful owner, primarily because such registration is only a perfection requirement in civil law and registration involves a great deal of time and money. For example, because a large extent of land is registered to owners from nearly 100 years ago, it has changed hands many times through inheritance, which means that today, it is extremely difficult to determine the actual owner (inheritor) without spending a great deal of time and money. However, if the profits to be obtained from the land do not justify such expense, the land remains unused as “owner-unknown land.”Buying and selling land under Japanese civil law requires an agreement from all landowners including in the case of shared ownerships; therefore, even if the land has high returns, if it is “owner-unknown land,” it cannot be used effectively. With a focus on unknown-owner land, in this section, four writers provide multifaceted perspectives on the causes thereof, the defects in the current system, and the possible solutions.Eminent domain, the system which allows the acquisition of land against the land owner’s will for public projects, is widely institutionalized in many countries. It works to mitigate the owner-unknown land issues as far as lands are acquired by public projects.Further, real estate auctions are often held when liens are placed on land and/or residences for housing loan defaults. The Japanese civil auction system, which was institutionalized at the end of the nineteenth century, stipulates that a tenancy that is behind on a mortgage may resist a purchase unconditionally as long as the mortgage default period is within 3 years (short-term lease protection system/former Civil Code Article 395). This system was intended to avoid the unstable use of mortgaged properties and to promote the effective use of real estate; however, because the majority of users and the beneficiaries of this system were in fact anti-social groups, it was used to demand money unjustly from debtors and buyers, thus preventing the effective use of the mortgaged properties.When the protection of short-term leases was abolished in 2004, these types of interferences are said to have decreased drastically. However, successful bids for auctioned real estate properties continue to be lower than in general transactions. Therefore, here, we provide a quantitative analysis of these situations and propose further auction system improvements.Below, we introduce the outlines of each theory in Part I.
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Pollak, E. "Quantitative Inheritance". W Encyclopedia of Genetics, 1595–97. Elsevier, 2001. http://dx.doi.org/10.1006/rwgn.2001.1057.
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Gai, J. "Quantitative Inheritance ☆". W Reference Module in Life Sciences. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809633-8.06989-2.
Pełny tekst źródłaStreszczenia konferencji na temat "Quantitative Inheritance"
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Mouhoubi, K., J. L. Bodnar, J. L. Nicolas, V. Detalle, J. M. Vallet i T. Duvaut. "Contribution to the local thermophysical characterization of murals paintings of the inheritance by stimulated infrared thermography". W 2014 Quantitative InfraRed Thermography. QIRT Council, 2014. http://dx.doi.org/10.21611/qirt.2014.123.
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Senthil, Velan S. "Quantitative Assessment of Inheritance Hierarchies for Aspect Oriented Software Development using a proposed Aspect Inheritance Reusability Model". W 2019 International Conference on Automation, Computational and Technology Management (ICACTM). IEEE, 2019. http://dx.doi.org/10.1109/icactm.2019.8776775.
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Jackson, C. W., N. K. Hutson, S. A. Steward i H. H. Edwards. "THE WISTAR-FURTH RAT: AN ANIMAL MODEL OF HEREDITARY MACRO THROMBOCYTOPENIA". W XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643925.
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The mechanisms which determine and regulate platelet size are unknown. By phase microscopy, we serendipitously observed that Wistar/Furth (W/F) rats had macrothrombocytopenia. In this study, we have characterized and compared platelets and megakaryocytes (MK) of W/F rats to those of Wistar (W), Long-Evans hooded (LE) and Sprague-Dawley (SD) rats. In addition, we have examined the mode of inheritance of this W/F rat platelet abnormality. Average platelet count of W/F rats was only 312 ± 57 x 103/mm3 compared to 1086 ± 68, 868 ± 91 and 926 ± 82 x 103/mm3 respectively for W, LE and SD rats. Mean platelet volume (MPV) of W/F rats (8.1 ± 1.4 fl) was twice that of W (4.0 ± 0.2 fl), LE (4.2 ± 0.3 f1) and SD (4.1 ± 0.2 f1) rats. However, average MK diameter and DNA content distribution of W/F rats were not significantly different than those of LE rats. Average MK concentration was somewhat lower (4.5 MK/high power field) in the W/F strain compared to that of LE rats (6.6 MK/HPF). Maze-like membrane formations were observed in W/F MK and platelets by electron microscopy. Reciprocal crosses of W/F and LE rats resulted in offspring with MPVs (4.2 fl) and platelet counts like those of LE rats, indicating that the macrothrombocytopenic trait is recessive in its inheritance. Reciprocal marrow transplants between the W/F and LE strains resulted in MPVs like those of the donor strain indicating that the macrothrombocytopenia is an intrinsic marrow abnormality of the W/F strain. Analysis of W/F platelets by two-dimensional polyacrylamide gel electrophoresis revealed two readily detectable differences from those of W and LE rats: (1) absence of a protein of MW of 41,000 and pi of 6.35 and (2) presence of a protein of MW of 35,000 and pi of 5.9. In summary, the W/F rat has a hereditary macrothrombocytopenia which is recessive in nature and not due to differences in MK size or DNA content. These results suggest that the macrothrombocytopenia of W/F rats results from formation of fewer platelets per MK, possibly due to a qualitative or quantitative defect in some component necessary for proper subdivision of megakaryocyte cytoplasm into platelets.
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Pease, Larry R., Sara J. Felts, Adam D. Scheid, Xiaojia Tang i Krishna R. Kalari. "Abstract P4-09-03: Phenotypes of breast tumor cells and normal lymphocytes are determined by the integration of minor changes in expression of multiple genes: A new dimension in quantitative inheritance". W Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-p4-09-03.
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Oliveira, Evelyn, Thaís Hudson Carneiro, Tiffany Marques dos Santos, Everaldo Soares Muniz i Claudia Cristina Soares Silva-Muniz. "Influence of cardiovascular risk factors for hereditary hypertension in the homeless population of São Paulo, Brazil". W III SEVEN INTERNATIONAL MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/seveniiimulti2023-098.
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Introduction: Systemic arterial hypertension (SAH) is a public health problem, affecting about 30% of Brazilians. Due to the multifactorial condition, its development, in cases of genetic predisposition, results from the association of genes and environmental factors, such as: sedentary lifestyle, stress, diet, dyslipidemia, obesity, among others. The hypertensive risk factors (RF) in the homeless population (PSR) gain relevance, due to their situation of vulnerability. Objective: To highlight the impact of cardiovascular RF on the development of hereditary hypertension in the homeless. Methodology: Exploratory, cross-sectional and quantitative study. Conducted by pre-structured questionnaire, approved by the Institutional Ethics Committee, CAAE: 21519413.40000.5511, applied between November 2021 and July 2022, in the central region of São Paulo; evaluating the lifestyle and cardiovascular RF of 119 volunteers aged 18 to 60 years, chosen for convenience. Results and Discussion: It was identified that 51.26% reported a family history of SAH. Of these, the average blood pressure was 154x102 mmHg, reporting that 21% suffer from stress, 44% are sedentary and 43% consume high concentrations of sodium in food. Therefore, it is possible to show that the presence of RF determines the tendency to express a hypertensive gene. Such factors play a crucial role in the activation of the sympathetic nervous system and renin-angiotensin system; leading to chemical modifications in the genome, characterizing the onset of SAH in genetically predisposed individuals. Conclusion: We highlight behaviors in the RSP that contribute to the development of hereditary SAH. Consequently, a multidisciplinary approach becomes essential in an attempt to find effective ways to reintegrate this population, aiming to change lifestyle habits. Therefore, just as modifiable RFs influence the manifestation of the disease, environmental stimuli resulting from healthy habits will induce essential changes against the inheritance of the hypertensive trait. Thus, we envision new studies on this theme, strengthening existing public policies and implementing new ones, with the preventive purpose.
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Paltrinieri, Nicola, Gabriele Landucci i Pierluigi Salvo Rossi. "Real-Time Data for Risk Assessment in the Offshore Oil and Gas Industry". W ASME 2017 36th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/omae2017-61486.
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Recent major accidents in the offshore oil and gas (O&G) industry have showed inadequate assessment of system risk and demonstrated the need to improve risk analysis. While direct causes often differ, the failure to update risk evaluation on the basis of system changes/modifications has been a recurring problem. Risk is traditionally defined as a measure of the accident likelihood and the magnitude of loss, usually assessed as damage to people, to the environment, and/or economic loss. Recent revisions of such definition include also aspects of uncertainty. However, Quantitative Risk Assessment (QRA) in the offshore O&G industry is based on consolidated procedures and methods, where periodic evaluation and update of risk is not commonly carried out. Several methodologies were recently developed for dynamic risk analysis of the offshore O&G industry. Dynamic fault trees, Markov chain models for the life-cycle analysis, and Weibull failure analysis may be used for dynamic frequency evaluation and risk assessment update. Moreover, dynamic risk assessment methods were developed in order to evaluate the risk by updating initial failure probabilities of events (causes) and safety barriers as new information are made available. However, the mentioned techniques are not widely applied in the common O&G offshore practice due to several reasons, among which their complexity has a primary role. More intuitive approaches focusing on a selected number of critical factors have also been suggested, such as the Risk Barometer or the TEC2O. Such techniques are based on the evaluation of technical, operational and organizational factors. The methodology allows supporting periodic update of QRA by collecting and aggregating a set of indicators. However, their effectiveness relies on continuous monitoring activity and realtime data capturing. For this reason, this contribution focuses on the coupling of such methods with sensors of different nature located in or around and offshore O&G system. The inheritance from the Centre for Integrated Operations in the Petroleum Industries represents the basis of such study. Such approach may be beneficial for several cases in which (quasi) real-time risk evaluation may support critical operations. Two representative cases have been described: i) erosion and corrosion issues due to sand production; and ii) oil production in environmental sensitive areas. In both the cases, dynamic risk analysis may employ real-time data provided by sand, corrosion and leak detectors. A simulation of dynamic risk analysis has demonstrated how the variation of such data can affect the overall risk picture. In fact, this risk assessment approach has not only the capability to continuously iterate and outline improved system risk pictures, but it can also compare its results with sensor-measured data and allow for calibration. This can potentially guarantee progressive improvement of the method reliability for appropriate support to safety-critical decisions.
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Liu, Yuhan, i Baosheng Wang. "Promoting indigenous cultural awareness through participatory game design with children". W 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002406.
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As urbanization progresses in China's rural areas, so do the severity of social issues, including the decline of social assets, the recession of agricultural industries, the lack of community cohesion, and a weak sense of belonging. A decline in cultural awareness is the reason behind such phenomena, which stems from changes to residents' lifestyles and a lack of cultural beliefs. This issue also results in insufficient cultural awareness, weak cultural inheritance, and neglect of cultural values among community residents. To this end, this paper aims to examine an educational model to enhance the cultural awareness of local community residents.At present, there are two types of education methods to enhance cultural awareness: passive types and active types. For example, passive education refers to the enhancement of participants’ cultural qualities through the problem-solving style lesson and ‘implicit’ curriculum, while an active education might use reflective writing or PD to promote cultural awareness. Of the two, active education, represented by PD, is more conducive to participants' acceptance of cultural knowledge. PD is also an effective method for developing humanitarianism in developing countries. It can be applied to the special scenario of rural communities in China as a new solution for raising the cultural awareness of residents. This paper shares a specific case study of enhancing residents' cultural awareness in community collective memory using participatory game design.A total of eight subjects were selected in this study. Since children are the future of the community's cultural development, the subjects included 6 children and 2 adults. Unlike traditional PD, this study focused on attracting the interests of subjects and enhancing their abilities to inherit traditional culture through participatory game design. The study consisted of three workshops: the cultural exploration workshop, the game design workshop, and the game testing workshop. Activity theory was used as a basis to guide the choice of time, location, and power dynamics, from which a framework of participatory activities covering the four approaches of "probing", "telling", "acting", and "making" was developed for the workshops. To further enhance collaboration, participants were also provided with a complete set of toolkits during the three workshops, including role-playing tools, game idea cards, house of cards, scaffolding, etc. At the end of each workshop, the Cultural Awareness Scale, which contains the three elements of cultural cognition, cultural heritage, and cultural values, was administered to measure the change in cultural awareness of the subjects. A mixed methods approach was used in analysis to uncover underlying cultural associations. The study qualitatively analyzed the transcribed spoken words and behaviors of the subjects using multimodal analysis, and quantitatively analyzed the variations in the word count of the text and the level of detail in the elaboration. In summary, this case study is important for examining cultural education models and improving the cultural awareness of the population. It also provides a framework of activities for participatory design workshops, which can serve as a reference for further research.
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Sas, G. "DEFECTS IN SERINE PROTEASE INHIBITORS". W XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643714.
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Several serine protease inhibitorsof plasma inhibit the activated coagulation enzymes but only antithrombin III(AT-III)and heparin cofactor II (HC-II) are implicated in the pathogenesisof the familial thrombosis. Since thefirst publication (1965) many thrombophilic families with reduced AT-III synthesis have been investigated. These studies have proved that the disorder is associated with a high risk forvenous thrombosis and the inheritanceis autosomal dominant. The AT-III activity in the plasma of the affected patients is about 50% of the normalvalue.In recent years the heterogeneity of the inherited AT-III deficiency has been verified. The various AT-III abnormalities are not mere interestingrarities but they provide naturally occurring models for the solution of theoretical problems such as the function of AT-III molecule, the physiological significance of heparin, etc. Furthermore, the clinical manifestationof the particular variants greatly differs from symptomless abnormality tosevere thrombotic cases.In the majority of cases, reduced functional activity is accompanied with a parallel decrease of antigen concentration of AT-III. This is the characteristic feature of the quantitative or Type I ("classical")AT-III deficiency. By means of crossed immunoelectrophoresis, electro-focussing and recombinant DNA techniques the heterogeneity of this group has been established. In one subgroup (Type la) AT-III molecules are normal as regards their biochemical characteristics. In Type lb, subnormal AT-IIIquantity is accompanied with decreased heparin affinity. Differentiation of these subgroups has practical consequences: therapeutic concentrations of heparin apparently does not decrease AT-III level in the plasma of patients with Type lb AT-III deficiency.The other main form is the qualitative deficiency of AT-III (Type II) which is characterised by reduced functional activity at normal antigen concentration. In general, two populations of AT-III molecules can be detected in the blood of these patients: a normal and an abnormal one. Up till now at least 24 different abnormalities were found and designatedwith toponymes. These disorders can be classified with relatively simple laboratory methods such as functional anti-IIaXaFirstDepartment of Medicine, Postgraduate Medical University, Budapest, Hungary.arin cofactor activity, crossed immunoelectrophoresiswith and without heparin, heparin-affinity chromatography. Type na is characterised by profound structural changes of the molecule,variably: reflected in reduced inactivation of F Ha and F Xa, abnormal heparin-AT-III reaction and aberrant immunochemical structure Seven different abnormalities fall into this group (Budapest I, Tokyo, MalmÖ, Chicago, Milano, Trento and Northwick Park). The last three abnormalities are very similar.In Type lib an isolated defect of protease inactivation can be detected and an isolated disturbance of the active centre ofthe molecule is assumed.Until now 6 apparently different variants belonging to this group have been described. (Aalborg, Vicenza, Denver, Hvidovre, Charleville, Milano 2.) Type lie abnormality is characterised by an isolated defect of the heparin-AT-III reaction. In these cases a disturbance of the heparin binding site(s) is assumed. Eleven families with this type of abnormality have been recorded (Ann Arbor, Basel, Paris 1 and 2, Toyama* Tours, Padova I and 2, Algers, Fontainebleu and Budapest 2). This subgroup is heterogeneous in respect ofheparin affinity: in the majority of cases the abnormal AT-III molecules have no heparin affinity at all while in rare cases (such as Basel, Budapest 2) they have reduced affinity.TheType lie AT-III deficiency has several distinctive features compared with the other subtypesJClinically, the thromboembolic complications are rare: in 4 families thrombosis has notoccurred at all. Only one member in each of 4 other families had thrombosis. In 3 families homozygous patients suffered severe thrombosis in young age and/or in unusual localisations (intraarterial, intracardiac, etc.) butthe other heterozygous members were free of thrombotic symptoms. No increased intravascular coagulation could be detected in Type lie heterozygous cases incontrast to the "classical" AT-III deficiency.These observations suggest a different mechanism and clinical manifestation of the deficiency of progressiveserine protease inactivation and of heparin cofactor activity. In case of progressive inactivation, reduction of 50% of the activity predisposes mainly to venous thrombosis as a consequence of the hypercoagulability of theblood. The isolated reduction of heparin cofactor activity seems to bringabout thrombosis in any part of the vascular system, but only if this reduction is as severe as that of the coagulant factors in case of coagulopathies.In accordance with this finding, rare cases of HCII deficiency give rise to thrombosis in both the arteries and the veins. Heparin cofactor activities may play an important role in the antithrombotic mechanism along theendothelial surface of the whole vascular system.
Raporty organizacyjne na temat "Quantitative Inheritance"
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Juvik, John A., Avri Bar Zur i Torbert R. Rocheford. Breeding for Quality in Vegetable Maize Using Linked Molecular Markers. United States Department of Agriculture, styczeń 1993. http://dx.doi.org/10.32747/1993.7568764.bard.
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Recently, the vegetable corn industry has shifted from the use of traditional cultivars with the sugary1 (su1) endosperm mutation to newer hybrids homozygous for the shrunken2 (sh2) or sugary enhancer1 (se1) genes. With greater kernel sucrose content, these hybrids are preferred by consumers and retain sugar for longer post harvest periods, providing the industry with more time to marker products with superior quality. Commercialization has been hindered, however, by reduced field emergence, and the establishment of stands with heterogeneous uniformity and maturities. This investigation was conducted to identify key biochemical and physiological characteristics in sh2 and se1 maize kernels associated with improved emergence, and stand establishment; and in immature ears at fresh harvest maturity, properties associated with eating quality. The location of genes or QTL controlling these kernel characteristics and other traits were then mapped to specific chromosomal regions by their linkage to molecular markers using two segregating F2:3 populations. This database was used to compare the efficiency of marker-assisted selection of key alleles with phenotypic selection for trait improvement. A model designed to uncover and quantify digenic interaction was applied to the datasets to evaluate the role of epistasis in the inheritance of quantitative traits.
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Fridman, Eyal, Jianming Yu i Rivka Elbaum. Combining diversity within Sorghum bicolor for genomic and fine mapping of intra-allelic interactions underlying heterosis. United States Department of Agriculture, styczeń 2012. http://dx.doi.org/10.32747/2012.7597925.bard.
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Heterosis, the enigmatic phenomenon in which whole genome heterozygous hybrids demonstrate superior fitness compared to their homozygous parents, is the main cornerstone of modern crop plant breeding. One explanation for this non-additive inheritance of hybrids is interaction of alleles within the same locus. This proposal aims at screening, identifying and investigating heterosis trait loci (HTL) for different yield traits by implementing a novel integrated mapping approach in Sorghum bicolor as a model for other crop plants. Originally, the general goal of this research was to perform a genetic dissection of heterosis in a diallel built from a set of Sorghum bicolor inbred lines. This was conducted by implementing a novel computational algorithm which aims at associating between specific heterozygosity found among hybrids with heterotic variation for different agronomic traits. The initial goals of the research are: (i) Perform genotype by sequencing (GBS) of the founder lines (ii) To evaluate the heterotic variation found in the diallel by performing field trails and measurements in the field (iii) To perform QTL analysis for identifying heterotic trait loci (HTL) (iv) to validate candidate HTL by testing the quantitative mode of inheritance in F2 populations, and (v) To identify candidate HTL in NAM founder lines and fine map these loci by test-cross selected RIL derived from these founders. The genetic mapping was initially achieved with app. 100 SSR markers, and later the founder lines were genotyped by sequencing. In addition to the original proposed research we have added two additional populations that were utilized to further develop the HTL mapping approach; (1) A diallel of budding yeast (Saccharomyces cerevisiae) that was tested for heterosis of doubling time, and (2) a recombinant inbred line population of Sorghum bicolor that allowed testing in the field and in more depth the contribution of heterosis to plant height, as well as to achieve novel simulation for predicting dominant and additive effects in tightly linked loci on pseudooverdominance. There are several conclusions relevant to crop plants in general and to sorghum breeding and biology in particular: (i) heterosis for reproductive (1), vegetative (2) and metabolic phenotypes is predominantly achieved via dominance complementation. (ii) most loci that seems to be inherited as overdominant are in fact achieving superior phenotype of the heterozygous due to linkage in repulsion, namely by pseudooverdominant mechanism. Our computer simulations show that such repulsion linkage could influence QTL detection and estimation of effect in segregating populations. (iii) A new height QTL (qHT7.1) was identified near the genomic region harboring the known auxin transporter Dw3 in sorghum, and its genetic dissection in RIL population demonstrated that it affects both the upper and lower parts of the plant, whereas Dw3 affects only the part below the flag leaf. (iv) HTL mapping for grain nitrogen content in sorghum grains has identified several candidate genes that regulate this trait, including several putative nitrate transporters and a transcription factor belonging to the no-apical meristem (NAC)-like large gene family. This activity was combined with another BARD-funded project in which several de-novo mutants in this gene were identified for functional analysis.