Rozprawy doktorskie na temat „Pyruvate”
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Debebe, Tewodros, Monika Krüger, Klaus Huse, Johannes Kacza, Katja Mühlberg, Brigitte König i Gerd Birkenmeier. "Ethyl pyruvate". Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-212525.
Pełny tekst źródłaBlalock, LeeAnn Talarico. "Expression of pyruvate decarboxylase in a Gram positive host Sarcina ventriculi pyruvate decarboxylase versus other known pyruvate decarboxylases /". [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0002366.
Pełny tekst źródłaWalker, Dianne. "Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335572.
Pełny tekst źródłaWexler, Isaiah David. "Disorders of pyruvate metabolism". Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1057937741.
Pełny tekst źródłaPeng, YI. "Pyruvate formate lyase and pyruvate formate lyase activating enzyme spectroscopic characteristics, interaction and mechanism /". Diss., Connect to online resource - MSU authorized users, 2008.
Znajdź pełny tekst źródłaJohnson, Sam. "Insulin regulation of pyruvate dehydrogenase". Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390644.
Pełny tekst źródłaBurthier, Jean Michel. "Les déficits en pyruvate déshydrogénase". Paris 5, 1990. http://www.theses.fr/1990PA05P176.
Pełny tekst źródłaCassady, Alan Ian. "Pyruvate carboxylase : a molecular biological study /". Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phc343.pdf.
Pełny tekst źródłaChen, Yiyuan. "Regulation studies on human pyruvate kinases". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33175.
Pełny tekst źródłaRobinson, Andrew James Cave. "Pyruvate kinase & glycolysis in potato". Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335799.
Pełny tekst źródłaHildyard, John Carl Westgarth. "Identification of the mitochondrial pyruvate carrier". Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410146.
Pełny tekst źródłaBurnett, Paul. "Intramitochondrial Ca'2'+ and pyruvate dehydrogenase". Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389169.
Pełny tekst źródłaCheung, Wing Yee. "A yeast pyruvate decarboxylase regulatory gene". Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37659.
Pełny tekst źródłaNaik, Sharon S. "Regulation of the pyruvate dehydrogenase complex". Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1062509957.
Pełny tekst źródłaJitrapakdee, Sarawut. "Characterisation of the pyruvate carboxylase gene and studies on the regulation of its expression in rat /". Title page, contents and summaryn only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phj6117.pdf.
Pełny tekst źródłaWorku, Netsanet, August Stich, Arwid Daugschies, Iris Wenzel, Randy Kurz, Rene Thieme, Susanne Kurz i Gerd Birkenmeier. "Ethyl pyruvate emerges as a safe and fast acting agent against Trypanosoma brucei by targeting pyruvate kinase activity". Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-179599.
Pełny tekst źródłaKhew-Goodall, Yee Sim. "Pyruvate carboxylase: its interactions with acetyl CoA /". Title page, table of contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phk454.pdf.
Pełny tekst źródłaMistry, Sharad C. "Longer term regulation of pyruvate dehydrogenase kinase". Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335116.
Pełny tekst źródłaRidout, Cheryl Kathleen. "Splicing mutations in pyruvate dehydrogenase subunit genes". Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526109.
Pełny tekst źródłaLovell, Simon Christopher. "Structural studies of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337172.
Pełny tekst źródłaDunford, Robin. "Pyruvate kinase and glycolytic control in potatoes". Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259704.
Pełny tekst źródłaMitchell, Rosie. "The regulation of human M2 pyruvate kinase". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21690.
Pełny tekst źródłaPotter, Simon. "Evaluation of pyruvate kinase as a potential phylogenetic marker : studies on the pyruvate kinase of the archaebacterium Thermoplasma acidophilum". Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20117.
Pełny tekst źródłaSeyda, Agnieszka. "Pyruvate dehydrogenase complex, correlation between structure and function". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ58921.pdf.
Pełny tekst źródłaZhong, Wenhe. "Biochemical and structural studies on trypanosomatid pyruvate kinases". Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/7725.
Pełny tekst źródłaSmolle, Michaela. "Molecular architecture of the human pyruvate dehydrogenase complex". Thesis, University of Glasgow, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439249.
Pełny tekst źródłaJones, Bethan Sian. "Regulation of pyruvate dehydrogenase complex by reversible phosphorylation". Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315644.
Pełny tekst źródłaMullick, Abdul. "Engineering the cooperativity of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388329.
Pełny tekst źródłaScotney, Pierre David. "The catalytic mechanism of Bacillus stearothermophilus pyruvate kinase". Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266959.
Pełny tekst źródłaWilliams, K. P. "Studies on pyruvate : ferredoxin oxidoreductase from Trichomonas vaginalis". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234978.
Pełny tekst źródłaAl-Amodi, Hiba Saeed Ahmed Bagader. "Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex". Connect to e-thesis, 2007. http://theses.gla.ac.uk/139/.
Pełny tekst źródłaPh.D. thesis submitted to the Division of Biochemistry & Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, 2007. Includes bibliographical references. Print version also available.
Brown, Audrey Elaine. "Constructing a recombinant model of the human pyruvate dehydrogenase complex". Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248119.
Pełny tekst źródłaBowker-Kinley, Melissa M. "Pyruvate dehydrogenase kinase Kinetics, site-directed mutagenesis, and regulation /". [Bloomington, Ind.] : Indiana University, 2005. http://wwwlib.umi.com/dissertations/fullcit/3183930.
Pełny tekst źródłaSource: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3690. Chair: Robert A. Harris. Title from dissertation home page (viewed Oct. 5, 2006).
Yazdanpanah, Mehrdad. "Pyruvate improves myocardial functional recovery after ischemia and reperfusion". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0028/MQ34078.pdf.
Pełny tekst źródłaHan, Hongmei. "Molecular characterization of pyruvate ferredoxin oxidoreductase from Helicobacter pylori". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ36459.pdf.
Pełny tekst źródłaHu, Liangyan. "Characterization of human pyruvate dehydrogenase kinase isoform 2 (PDHK2". Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/856.
Pełny tekst źródłaGao, Xueliang. "Nuclear Pyruvate Kinase M2 Functional Study in Cancer Cells". Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/biology_diss/89.
Pełny tekst źródłaPulido-Cejudo, Gabriel. "Chemical and biological properties of iron-pyruvate-transferrin complexes". Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74529.
Pełny tekst źródłaDenyer, G. "Regulation of hepatic pyruvate dehydrogenase complex by reversible phosphorylation". Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233529.
Pełny tekst źródłaDay, S. E. "Detection of tumour treatment response using hyperpolarized 13C pyruvate". Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598434.
Pełny tekst źródłaAbayomi, Louise Anike. "Disposable pyruvate biosensors for routine assessment of onion flavour". Thesis, Cranfield University, 2007. http://dspace.lib.cranfield.ac.uk/handle/1826/5663.
Pełny tekst źródłaStewart, Melanie Ann. "Fatty acids and the regulation of pyruvate dehydrogenase interconversion". Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:d05910c0-f7a1-4363-ac2c-a9a1eb857964.
Pełny tekst źródłaWard, Jason David. "Targeting, assembly and regulation of the pyruvate dehydrogenase complex". Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264108.
Pełny tekst źródłaDave, Emma. "The physiology of the Escherichia coli pyruvate dehydrogenase complex". Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364242.
Pełny tekst źródłaCanas, Ana. "Acetoin production from pyruvate in Leuconostoc mesenteroides NCDO 518". Thesis, University of Reading, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319244.
Pełny tekst źródłaPoole, Robert C. "Transport of lactate and pyruvate across mammalian plasma membranes". Thesis, University of Bristol, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330043.
Pełny tekst źródłaAllen, Mark Devin. "Interaction of protein domains in pyruvate dehdrogenase multienzyme complex". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242899.
Pełny tekst źródłaTulloch, Lindsay B. "Pyruvate kinase from Leishmania mexicana as a chemotherapeutic target". Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/14592.
Pełny tekst źródłaMcNally, Teresa. "Studies on the allosteric control of yeast pyruvate kinase". Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/19133.
Pełny tekst źródłaSeyran, Sevde Berfin. "Metabolic functions of the multifunctional protein E4F1 in skin homeostasis". Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT024/document.
Pełny tekst źródłaThe multifunctional protein E4F1 is an essential regulator of normal skin homeostasis. During my Phd, I demonstrated that E4f1 inactivation in adult skin results in stem cell autonomous defects causing exhaustion of the epidermal stem cell (ESC) pool. At the molecular level, I identified E4F1 as a new regulator of the pyruvate dehydrogenase complex (PDC) in keratinocytes, an essential mitochondrial complex that converts pyruvate into Acetyl-CoEnzyme A. Using genetically engineered mouse models, I showed that E4F1-mediated control of PDH activity is required to maintain normal skin homeostasis. Consistently, E4F1 deficiency in basal keratinocytes resulted in deregulated expression of dihydrolipoamide acetlytransferase (Dlat), a gene encoding the E2 subunit of the PDC, and impaired PDH activity. The metabolic reprogramming of E4f1 KO keratinocytes associated with the redirection of the glycolytic flux towards lactate production and increased lactate secretion in their microenvironment, leading to enhanced activity of extra-cellular-matrix remodelling proteases Finally, these defects ended in alterations of the basement membrane, ESC mislocalization and the exhaustion of the ESC pool. In the second part of my thesis, I have evaluated the role of E4F1-mediated control of the PDC in melanocytes and showed that the metabolic activities of E4F1 are important for melanocyte function. Consistently, mice with E4f1-deficient melanocytes exhibited hair graying and skin pigmentation defects. Altogether, my data demonstrate the importance of E4f1-mediated control of pyruvate metabolism for normal skin homeostasis