Rozprawy doktorskie na temat „Pulmonary imaging”
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Yoshimaru, Eriko Suzanne. "Magnetic Resonance Imaging Techniques for Rodent Pulmonary Imaging". Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/293388.
Pełny tekst źródłaSaba, Tarek Sami. "The assessment of pulmonary haemodynamics with magnetic resonance imaging in pulmonary hypertension". Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/29346.
Pełny tekst źródłaSchuessler, Thomas Florian. "Advances in pulmonary monitoring and thoracic imaging". Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=34444.
Pełny tekst źródłaSchuessler, Thomas F. "Advances in pulmonary monitoring and thoracic imaging". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ30376.pdf.
Pełny tekst źródłaVan, Tassel Lora. "Imaging Evaluation of the Solitary Pulmonary Nodule". Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/221418.
Pełny tekst źródłaAn estimated 150,000 solitary pulmonary nodules (SPNs) are identified at chest radiography each year, making it important for physicians to understand how to characterize them and evaluate patients for potential malignancy. We performed an extensive literature search to identify risk factors, characteristics of SPNs, and available technologies used to identify and evaluate these nodules through a comprehensive literature search. Additionally, we present evidence-based management schemes for incidentally identified nodules. CONCLUSIONS: A number of features visible at thoracic CT are useful for determining whether an SPN is benign or malignant. FDG PET/CT plays an important role in the diagnosis and management of lung cancer and is an increasingly valuable tool for the characterization and management of SPNs. Unlike CT and MRI imaging, PET provides metabolic activity of a nodule. The information provided by PET/CT imaging allows for both morphological and anatomical characteristics as well as physiological data in the form of metabolism within the nodule itself. The information gained from PET is extremely useful for directing patient management and may obviate the need for invasive diagnostic procedures.
Johns, Christopher. "Improving the diagnostic pathway of pulmonary hypertension using cardio-pulmonary magnetic resonance imaging". Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/20207/.
Pełny tekst źródłaMcLeod, Karen A. "Intravascular ultrasound and magnetic resonance imaging of the pulmonary arteries in pulmonary hypertension". Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/28597.
Pełny tekst źródłaWang, Lei. "FDG-PET imaging of pulmonary vascular remodelling in PAH". Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/58197.
Pełny tekst źródłaWalvick, Ronn P. "Magnetic Resonance Imaging of Neural and Pulmonary Vascular Function". Digital WPI, 2010. https://digitalcommons.wpi.edu/etd-dissertations/372.
Pełny tekst źródłaMiele, Amy Caroline. "Comparative pulmonary fibrosis : imaging fibroproliferation in donkey and man". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/17885.
Pełny tekst źródłaRajaram, Smitha. "Imaging in pulmonary hypertension : the role of MR and CT". Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/6959/.
Pełny tekst źródłaSwift, Andrew J. "Developing the role of magnetic resonance imaging in pulmonary hypertension". Thesis, University of Sheffield, 2012. http://etheses.whiterose.ac.uk/3216/.
Pełny tekst źródłaJasinowodolinski, Dany. "Estudo da perfusão pulmonar por angiotomografia computadorizada em pacientes com hipertensão pulmonar". Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-01122014-144947/.
Pełny tekst źródłaBackground: Pulmonary arterial hypertension (PAH) is a severe disease of the pulmonary circulation. Right heart catheterization (RHC) is crucial for diagnosis and management of these patients. High-resolution computed tomography (CT) and CT angiography play a crucial role in the diagnostic work-up of pulmonary hypertension. Dual energy computed tomography (DECT) is a technique of acquisition of modern CT scanners that allows obtaining a computed tomography of the pulmonary arteries with low iodine dose, and providing an estimation of iodine distribution in the lungs. Although the search for non-invasive methods for evaluation of PAH is developing, data concerning application of DECT on PAH patients remain scarce. Objectives: To evaluate the iodine distribution in the lungs obtained by DECT in PAH patients and a control group and compare to the hemodynamic profile, and prognostic markers of PAH patients. Methods: 21 patients followed at the Pulmonary Circulation Unit (InCor-HCFMUSP) and submitted to CT angiography were evaluated by DECT. A matched control group was composed by patients routinely referred to CT angiography to rule out pulmonary embolism with negative results and also a normal echocardiogram obtained at the same day. Eight circular 1cm2 ROIs were placed along the anteroposterior axis, at the middle of the right lung and at predetermined levels to measure the Iodine concentration in the lungs. Measurements of the pulmonary artery (PA), ascending aorta (AO), right ventricle (RV) and left ventricles (LV) were obtained, as well as enhancement of the PA (PAenh). Results were compared to the control group, and correlated with hemodynamic parameters in the PAH group. Results: PAH patients averaged 42 y/o, female/male ratio of 7/1, NYA functional classes I/II. Statistically significant differences between PAH patients and controls were found regarding measurements of PA (p < 0,01), RV (p < 0,01), LV (p=0,01), PA/AO (p < 0,01) and RV/LV (p < 0,01). PA diameter greater than 2,9 cm and PA/AO ratio greater 1,1 were diagnostic for pulmonary hypertension with sensitivity/specifity of 90,5%/100% and 87,5%/100%. PAenh showed no statistical difference between PAH patients and controls . A characteristic anteroposterior Iodine concentration gradient was found in all subjects, both PAH patients showed lower Iodine concentration diffusely (p < 0,01). When corrected by PAenh, Iodine gradients showed no statistical difference between PAH patients and controls. PAenh correlates with cardiac output (r=-0,661), and mPaP correlates with PA/AO ratio (r=0,676), RV/LV ratio VD/VE ratio (r=0,679), and p<0,01. Conclusion: Anteroposterior Iodine concentration gradient is preserved in PAH in comparison with controls, but with lower magnitude. This difference was corrected through the multiplication of individual Iodine measurements by PAenh, suggesting that this could be explained by lower blood flow to the lungs of PAH patients. PAenh correlates with cardiac output, mean pulmonary arterial pressure correlates with PA/AO and RV/LV in PAH patients. DECT provided conventional anatomic measurements and allowed the characterization of preserved anteroposterior Iodine gradients in PAH patients, with decreased magnitude in comparison with controls, that could be atributed to a lower CO of these patients
Nilsson, Tage. "Pulmonary embolism : validation of diagnostic imaging methods in the clinical setting /". Stockholm : Karolinska institutets bibl, 2002. http://diss.kib.ki.se/2002/91-7349-346-5.
Pełny tekst źródłaBlyth, Kevin G. "Magnetic resonance imaging of the right ventricle in human pulmonary hypertension". Thesis, Connect to e-thesis, 2008. http://theses.gla.ac.uk/248/.
Pełny tekst źródłaMD. thesis submitted to the Faculty of Medicine, Division of Cardiovascular and Medical Sciences, 2007. Includes bibliographical references. Print version also available.
Karmouty, Quintana Harry. "Experimental pulmonary disease assessed non-invasively by magnetic resonance imaging (MRI)". Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437768.
Pełny tekst źródłaNeal, Mary Agnes. "19F-MRI of inhaled perfluoropropane for quantitative imaging of pulmonary ventilation". Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3963.
Pełny tekst źródłaStecker, Ian. "Optimizing Quantitative Methods in Murine Pulmonary Imaging with UTE 1H MR". University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592135581719325.
Pełny tekst źródłaConway, Joy Helen. "The assessment of intra-pulmonary deposition of aerosols using multi-modality imaging". Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242562.
Pełny tekst źródłaNamati, Eman, i eman@namati com. "Pre-Clinical Multi-Modal Imaging for Assessment of Pulmonary Structure, Function and Pathology". Flinders University. Computer Science, Engineering and Mathematics, 2008. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20081013.044657.
Pełny tekst źródłaLivieratos-Petratos, George N. "Neural networks for computer aided diagnosis of pulmonary images in nuclear medicine". Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295017.
Pełny tekst źródłaBrewis, Melanie J. "Imaging right ventricular function to predict outcome in patients treated for pulmonary hypertension". Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/7888/.
Pełny tekst źródłaLiu, Yifei. "A Correlative Workflow for Imaging Murine Extracellular Matrix to Determine Pulmonary Valve Biomechanics". The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1619095019644309.
Pełny tekst źródłaJose, Arun. "Value of Baseline Cardiac Magnetic Resonance Imaging for Predicting Adverse Outcomes in Treatment-naive Pulmonary Hypertension Patients". University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1560866307524617.
Pełny tekst źródłaISHIGAKI, TAKEO, MITSUHIKO HIROSE, KIYOKO NAKAMURA, MITSURU IKEDA, KENGO ITO i NICOLAS MILLA. "FUNDAMENTAL AND CLINICAL EVALUATION OF CHEST COMPUTED TOMOGRAPHY IMAGING IN DETECTABILITY OF PULMONARY NODULE". Nagoya University School of Medicine, 1994. http://hdl.handle.net/2237/16074.
Pełny tekst źródłaCederlund, Kerstin. "Radiological imaging of pulmonary emphysema : preoperative evaluation of candidates for lung volume reduction surgery /". Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-195-0.
Pełny tekst źródłaSauret, Veronique. "Topology and morphology of pulmonary anatomical features for aerosol deposition applications using medical imaging". Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342803.
Pełny tekst źródłaLee, Namheon. "Assessment of Pulmonary Insufficiency using Energy-Based Endpoints and 4D Phase Contrast MR Imaging". University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1384865927.
Pełny tekst źródłaCrawley, Stephen F. "Cardiac magnetic resonance imaging in the diagnosis and determination of outcome of pulmonary hypertension". Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7431/.
Pełny tekst źródłaKannan, Arun, Chithra Poongkunran, Mahendran Jayaraj i Rajesh Janardhanan. "Role of Strain Imaging in Right Heart Disease: A Comprehensive Review". Elmer, 2014. http://hdl.handle.net/10150/621330.
Pełny tekst źródłaWang, Maisie S. "Ultra-high resolution imaging and artery-vein separation of blood pool contrast-enhanced MRA /". Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8094.
Pełny tekst źródłaStone, Ian. "Effects of COPD and its treatment on cardiovascular structure and function assessed through advanced imaging techniques". Thesis, Queen Mary, University of London, 2016. http://qmro.qmul.ac.uk/xmlui/handle/123456789/23199.
Pełny tekst źródłaJardim, Carlos Viana Poyares. ""Avaliação da distensibilidade da artéria pulmonar através da ressonância magnética e sua relação com a resposta ao teste agudo com vasodilatador em pacientes com hipertensão arterial pulmonar"". Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-12092005-103213/.
Pełny tekst źródłaPulmonary arterial hypertension is characterized by an increase in pulmonary vascular resistance, eventually leading to hemodynamic failure. We assessed whether pulmonary artery distensibility (evaluated by magnetic resonance) correlated with acute vasodilator test response. A statistically significant difference was found in terms of pulmonary artery distensibility in responders and non-responders. A ROC curve showed that 10% distensibility could discriminate responders from non-responders with 100%sensitivity and 56% specificity
Wielopolski, Piotr Alfred. "Three-dimensional magnetic resonance imaging of the pulmonary vascular system with rapid gradient echo acquisitions". Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1060277751.
Pełny tekst źródłaUnglert, Carolin [Verfasser]. "Quantitative optical coherence tomography for imaging healthy and emphysematous pulmonary alveoli in vivo / Carolin Unglert". Lübeck : Zentrale Hochschulbibliothek Lübeck, 2014. http://d-nb.info/1050912241/34.
Pełny tekst źródłaMatin, Tahreema Nihad Hashmi. "Functional lung assessment using hyperpolarised xenon gas magnetic resonance imaging". Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:61e77bfb-67d9-4221-b246-4a5cd66b5144.
Pełny tekst źródłaSoerensen, Dennis Dam. "Optimization and Analysis of The Total Cavo-Pulmonary Connection". Thesis, Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/10444.
Pełny tekst źródłaAl, Jefairi Nora. "Leads to improve atrial fibrillation ablation, catheters, imaging and mapping guidance". Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0834/document.
Pełny tekst źródłaAtrial fibrillation (AF) is the most common form of cardiac arrhythmia in Humans. Pulmonary vein isolation (PVI) by radiofrequency (RF) ablation is the mainstay treatment for patients with symptomatic and drug refractory paroxysmal atrial fibrillation (PAF) as ectopic beats (triggers) from pulmonary veins (PVs) initiate AF, however PVI alone had limited role in treating patients with persistent atrial fibrillation (PsAF), due to additional involvement in left atrium (LA) by electrical and anatomical remodeling, creating more complex substrate (fibrosis) that maintain AF and therefore necessitate non-PV sites ablation to modify the arhythmogenic substrate. Atrial fibrillation recurrence mainly due to pulmonary vein (PV) electrical reconnection is common and remains the current issue that limits long term procedural success and generates extra costs due to repeated hospital admissions and repeated procedures. Point by point ablation using single tip catheter can be challenging, complex and time consuming, enhancing electrical reconnection as stable lesions are difficult to achieve. To overcome these limitations, new type of catheters such as balloon (cryoablation) and multi-electrode circular ablation catheters like PVAC and nMARQ, are now available. However, cryoablation balloon is limited by inability to adapt to anatomic PV variability and to ablate non-PV sites. This means that an additional ablation catheter has to be used for non-PV targets, and it certainly adds to the costs. The PVAC catheter lacks of irrigation increases the risk of thromboembolic complications. On contrary, nMARQ is an irrigated circular ablation catheter which in addition to its role in PVI, allows for non-PV/LA substrate ablation. Cardiac mapping and imaging tools are now commonly used to plan and guide AF ablation, such as invasive (Carto 3) and noninvasive (ECVUE) electroanatomic mapping (EAM), computed tomography (CT) and magnetic resonance imaging (MRI), respectively. We hypothesized that different strategies and technologies could improve PVI procedure and outcome by producing better lesions and by allowing for direct visualization of lesions. We therefore, assessed the role of circular, irrigated mapping and ablation catheter (nMARQ) in PAF and PsAF with or without noninvasive ECGi guidance, and advanced imaging technologies (MRI) after PVI. For that purpose, PVI data were obtained and processed acutely and at 3 months. Clinical follow up was evaluated at 1 year. The thesis consists of 3 parts: Part 1: How to improve pulmonary vein isolation lesion formation in patients with paroxysmal atrial fibrillation? Part 2: Circular catheter and persistant atrial fibrillation ablation. Part 3: The role for magnetic resonance imaging in assessing pulmonary vein reconnection after pulmonary vein isolation?
Akinyi, Teckla G. "An Affordable Open-Source Small Animal MR and Hyperpolarized Gas Compatible Ventilator: Feasibility in preclinical imaging". University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1490354672385997.
Pełny tekst źródłaBlé, François-Xavier Frossard Nelly Beckmann Nicolau. "Lung magnetic resonance imaging as a non-invasive alternative to assess experimental pulmonary diseases in small rodents". Strasbourg : Université Louis Pasteur, 2008. http://eprints-scd-ulp.u-strasbg.fr:8080/996/01/BLE_FrancoisX2_2007.pdf.
Pełny tekst źródłaBlé, François-Xavier. "Lung magnetic resonance imaging as a non-invasive alternative to assess experimental pulmonary diseases in small rodents". Université Louis Pasteur (Strasbourg) (1971-2008), 2007. https://publication-theses.unistra.fr/public/theses_doctorat/2007/BLE_Francois-Xavier_2007.pdf.
Pełny tekst źródłaMagnetic resonance imaging (MRI) is able to detect water content in the biological tissue and thus to non-invasively assess on a regional basis infiltrated water and/or secreted fluids and/or tissue densification. In pulmonary diseases such as asthma, chronic obstructive pulmonary diseases or fibrosis, plasma exudation, mucus secretion and thickening of the lung tissue constitute hallmarks of the pathological status that directly contribute to functional impairment. These features are well conserved in experimental pulmonary disease models in the small rodents. A particular interest is given to murine models that have provided, in parallel to the technological progress in genetic engineering and molecular biology, a reliable in vivo support for lung disease understanding and investigation. Nowadays, routine methods used to evaluate disease state of the lung in these models are either terminal or gives functional estimation of the global airways. Therefore, we have set up a method using MRI technique to non-invasively depict different hallmarks occurring in a murine model of asthma. In this thesis, we have demonstrated that proton MRI provides a relevant mean to assess and follow signals associated with the plasma leakage and mucus secretions in the lung, which are both important features of the inflammatory response following allergenic provocation. To further confirm these findings, we have also validated in this model the effect of pharmacological tools. We chose to study sphingosine-1-phosphate (S1P) pharmacology on the basis of recent publications indicating a possible implication of this endogenous mediator in inflammation and lung barrier integrity in models of asthma. In two studies examining the effects of the general S1P agonist FTY720 and of the S1P2 antagonist JTE013, the incidence of plasma leakage on fluid signal detection was highlighted in our murine model of airway inflammation and confirmed by histology and BAL fluid analyses. Additionally, since the technique had been previously set up in the rat, we extended the knowledge in this species. In this regard, we achieved the selective detection and monitoring of mucus dynamics by MRI with the use of a specific contrast agent in a model of endotoxin-induced mucus hypersecretion. Besides, we also demonstrated the capabilities of MRI to follow the hydration of airway secretions. In this non-inflammatory model, the formation of MRI fluid signals were induced by hypertonic saline instillation and dose-dependently enhanced by different compounds that interact directly or indirectly with epithelial Na+ channel (ENaC), a major regulator of airway surface liquid hydration. These studies have been successfully performed in the rat with the perspective of future translation to murine models for transgenic application. Finally, we have partially validated the application of this technique to a less acute model, the murine bleomycin-induced fibrosis. This model has been chosen regarding its admitted relevance to mimic global characteristics of human pulmonary fibrosis in addition to its simplicity to be set up. In this study, we have been able to follow by MRI the course of edematous, mucous and/or fibrotic features in correlation with histological findings. In summary, the present work is bringing evidence of possible contributions of MRI in pulmonary disease investigations in mouse and rat, and postulates for its use to complete and/or replace the methods used nowadays to evaluate experimental murine models
McLure, Lindsey Elizabeth Robertson. "The role of cardiac magnetic resonance imaging in the assessment of right ventricular function in pulmonary hypertension". Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6884/.
Pełny tekst źródłaBoulate, David. "L'évaluation du ventricule droit dans l'hypertension pulmonaire". Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS500/document.
Pełny tekst źródłaRight heart failure is the leading cause of mortality in patients with pulmonary hypertension (PH). At early stage of PH the right ventricle (RV) remodels to adapt to the increased pulmonary vascular resistances. This adaptation is characterized by morphological, functional and myocardial changes. The evaluation of these changes may be applied for screening, prognosis evaluation and follow-up of patients with PH. However, the pathophysiology of the transition from adaptive to maladaptive phenotypes remains unclear; and identification of RV therapeutic targets and noninvasive methods for its evaluation remains to developed. The aim of this thesis was to evaluate non-invasive screening of PH with echocardiography and to study the pathophysiology of acute right heart failure in the setting of chronic PH by performing precise phenotyping of a new large animal model. A wide review of anatomic, embryologic and physiologic concepts was performed to help for the understanding of parameters of RV evaluation; then published and ongoing original studies were presented.In a first study, we investigated PH screening with echocardiography in patients with advanced lung disease. In this study, we showed that enlargement of the RV and of the right atrium, as well as function parameters of the RV were associated with PH. When the tricuspid regurgitation was available (52% of cases), RV morphology and function parameters did not improve PH diagnosis. Abnormal RV morphology and function without available tricuspid regurgitation provided moderate detection value; whereas 20% of patients without PH presented enlargement of the RV. In a large animal model with progressive increase in pulmonary artery mechanical obstruction, enlargement of the RV was the earliest RV parameter associated with PH development. This study highlights the need for more specific RV indices of PH.In a second study we investigated right ventricular changes in a new large animal model of acute right heart failure occurring on chronic PH; a situation associated with around 40% mid term mortality or transplantation. We characterized right ventricular changes during acute volume and pressure overload and after hemodynamic restauration in a large animal model of chronic thromboembolic PH. The RV was evaluated with parameters derived from pressure-volume loops, echocardiography, right heart catheterism and with circulating biomarkers. Pathological and proteins content analyzes of the RV around 3 hours after hemodynamic restauration showed acute subendocardial and subepicardial focal ischemic lesions as well as signs of autophagy activation. We found similar ischemic lesions in RV of 5 patients who underwent a heart-lung transplantation for PH in the setting of hemodynamic compromise. Preliminary data suggest that these lesions are associated with end-organ injury and poor overall survival after heart-lung transplantation in patients with PH.In conclusion, abnormal echocardiographic right heart metrics may be observed in patients with advanced lung disease without PH limiting their use for PH screening in this population. This highlight the need for more specific right heart metrics associated with PH. At the other extreme of the spectrum of PH severity, we described for the first time a large animal model of acute right heart failure in chronic PH. We reproduced and described the main morphological and functional features observed in acute right heart failure on PH and we showed for the first time that acute right ventricular ischemic lesions may develop within few hours despite hemodynamic restauration with dobutamine. These data provide a strong rational to develop specific biomarkers to evaluate tissue lesions of the right ventricle and determine their clinical implications
Sweers, Lynelle. "The scintigraphic evaluation of the pulmonary perfusion pattern of dogs hospitalised with babesiosis". Diss., Electronic thesis, 2007. http://upetd.up.ac.za/thesis/available/etd-05082008-153547/.
Pełny tekst źródłaTonelotto, Bruno Francisco de Freitas. "Determinação da PEEP ideal e avaliação de atelectasia pulmonar com o uso da ultrassonografia durante intraoperatório de cirurgias eletivas". Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-27022019-151124/.
Pełny tekst źródłaPurpose: Intraoperative atelectasis occurs immediately after anaesthetic induction and can be detected by lung ultrasound (LUS). However, LUS is considered as unable to assess pulmonary hyperinflation. In this study, we propose a method to detect pulmonary hyperinflation using LUS. Electrical impedance tomography (EIT) was the reference method. Methods: We included 18 patients, 63 ± 6-year old, with normal lungs, undergoing lower abdominal surgery. The following protocol was used: EIT was calibrated, followed by anaesthetic induction, intubation and mechanical ventilation. To reverse posterior atelectasis, a recruitment maneuver - positive end-expiratory pressure (PEEP) 20 cmH20 and plateau airway pressure 40 cmH2O during 120 sec was performed. PEEP titration was then obtained during a descending trial: 20, 18, 16, 14,12,10, 8, 6 and 4 cmH2O. Ultrasound and EIT data were collected at each PEEP level and analyzed by two independent observers. The number of H lines was counted using a special filter. Spearman correlation test and ROC curve were used to compare LUS and EIT data. Results: The number of H lines increased linearly with PEEP: from 3 at PEEP 4 cmH2O to 10 at PEEP 20 cmH2O. Five H lines was the threshold for detecting pulmonary hyperinflation, defined as a mean decrease in maximum EIT compliance >= 24,5 %. The area under the ROC curve was 0.947 (CI 95% 0.901-0.976). Conclusion: Intraoperative transthoracic LUS can detect pulmonary hyperinflation during a PEEP descending trial. Five or more H lines can be considered as indicating pulmonary hyperinflation in normally aerated lung regions
Santos, Vitor Vasquez dos. "Semi-quantificação cintilográfica de defeitos perfusionais em portadores de Doença Falciforme. Comparação com sintomas clínicos". Botucatu, 2019. http://hdl.handle.net/11449/182321.
Pełny tekst źródłaResumo: Introdução: A doença falciforme (DF) é a doença monogênica herdada mais comum no mundo. Acometimentos cardiopulmonares de caráter progressivo associados à vaso oclusão e fenômenos embólicos assim como, as exacerbações de sintomas respiratórios são causas recorrentes de internações nessa população. A cintilografia de perfusão é método de imagem sensível e consagrado para avaliação hipoperfusão pulmonar, notadamente em processos embólicos. A semi-quantiticação da porcentagem de obstrução vascular de perfusão (POVF) apresenta relação segura com a angiografia. Objetivo: 1) Verificar a correlação entre os sintomas clínicos (Classes funcionais) versus Porcentagem de defeitos perfusionais (POVF%) em portadores de DF e 2) Verificar a associação entre POVF% e espirometria, avaliada pela porcentagem da capacidade vital forçada do predito (CVF%). Casuística e Metodologia Trata-se de estudo transversal observacional descritivo de 22 portadores de Doença Falciforme (DF), com coleta retrospectiva de dados clínicos e de espirometria, no período de 2017-2019 e semi-quantificação da cintilografia de perfusão pulmonar (POVF%), CF de I a IV e CVF% Análise estatística descritiva e inferenciais (Coeficiente de correlação – CC), com nível de significância com p<0,05. Resultados: Foram observados cinco subtipos de DF: SS (n=13), BSB0 (n=04), SS+alfatalassemia (n=02), SS+ fetal elevada (n=02) e SC (n=1). A cintilografia de perfusão pulmonar foi sensível identificando defeitos perfusionais em 91% da ... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: INTRODUCITON: Sickle cell disease (SCD) is the most common inherited monogenic disease in the world. Cardiopulmonary complications of a progressive character, associated with vessel occlusion and embolic phenomena, such as, exacerbations of respiratory symptoms are recurrent causes of hospitalization in this population. Perfusion scintigraphy is a sensitive and conspicuous imaging method for evaluating pulmonary hypoperfusion, especially in embolic processes. The semi-quantification of the percentage of vascular perfusion obstruction (POVF) presents a safe relationship with angiography. Objective: 1) To verify the correlation between clinical symptoms (functional classes- FC) versus percentage of perfusion defects (POVF%) in patients with CSD and 2) to verify the association between POVF% and spirometry, evaluated by the percentage of forced vital capacity predicted VCF%). MATERIALS AND METHODOLOGY This was a descriptive, observational cross-sectional study of 22 patients with SCD, with retrospective collection of clinical data and spirometry data for the period 2017-2019 and semi-quantification of pulmonary perfusion scintigraphy (POVF%) , FC from I to IV and VCF% Descriptive and inferential statistical analysis (Coefficient of correlation - CC), with level of significance with p <0.05. Results: Five subtypes of SCD: SS (n = 13), BSB0 (n = 04), SS + alphatassemia (n = 02), high fetal SS + (n = 02) and SC (n = 1) were observed. Pulmonary perfusion scintigraphy was sensitive b... (Complete abstract click electronic access below)
Mestre
Yaroshenko, Andriy [Verfasser], Franz [Akademischer Betreuer] [Gutachter] Pfeiffer i Axel [Gutachter] Haase. "X-ray dark-field imaging for diagnosis of pulmonary disorders / Andriy Yaroshenko. Betreuer: Franz Pfeiffer. Gutachter: Axel Haase ; Franz Pfeiffer". München : Universitätsbibliothek der TU München, 2015. http://d-nb.info/1103658328/34.
Pełny tekst źródłaVarghese, Juliet Jaison. "A Magnetic Resonance Imaging Method to Non-Invasively Measure Blood Oxygen Saturation". The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1471622211.
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