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Rozprawy doktorskie na temat „PTX”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 11 marca 2023

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1

Atkinson, Allen Bradley Jr. "A Model for the PTX Properties of H2O-NaCl." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/34376.

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In many geologic environments, fluids have compositions that are approximated by the H<sub>2</sub>O-NaCl system. When minerals grow in the presence of such fluids, some of the solution is trapped in the growing mineral as fluid inclusions. The salinity, temperature of homogenization, and pressure of homogenization are required to predict the trapping conditions of the fluid inclusion. In the laboratory the salinity and the temperature of homogenization of the trapped fluid are easily determined however, the pressure of homogenization cannot be determined directly, and must be calculated from

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2

Burgess, Vanessa Anne, and n/a. "Toxicology Investigations With The Pectenotoxin-2 Seco Acids." Griffith University. School of Public Health, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030905.090222.

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Pectenotoxins (PTXs) are a group of large cyclic polyether compounds associated with diarrhetic shellfish poisoning (DSP) as they are often found in combination with other DSPs such as okadaic acid (OA) and dinophysis toxins (DTXs) in shellfish. Although classified and regulated with the DSPs, there is debate over whether these toxins should be classified with DSP toxins. To date, ten different analogues of PTXs have been identified from shellfish and algae, and of these, the pectenotoxin-2 seco acids (PTX2-SAs) are of particular interest as they have previously been implicated in a shellfish

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3

Burgess, Vanessa Anne. "Toxicology Investigations With The Pectenotoxin-2 Seco Acids." Thesis, Griffith University, 2003. http://hdl.handle.net/10072/365382.

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Pectenotoxins (PTXs) are a group of large cyclic polyether compounds associated with diarrhetic shellfish poisoning (DSP) as they are often found in combination with other DSPs such as okadaic acid (OA) and dinophysis toxins (DTXs) in shellfish. Although classified and regulated with the DSPs, there is debate over whether these toxins should be classified with DSP toxins. To date, ten different analogues of PTXs have been identified from shellfish and algae, and of these, the pectenotoxin-2 seco acids (PTX2-SAs) are of particular interest as they have previously been implicated in a shellfish

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4

Lee, Mei Ki. "Chemokine signaling via PTX-insensitive G proteins : activation of transcription factors and chemotaxis /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?BICH%202007%20LEE.

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Santos, Paulo Carlos Ferreira dos. "Extração de informações de desempenho em GPUs NVIDIA." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/45/45134/tde-02042013-090806/.

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O recente crescimento da utilização de Unidades de Processamento Gráfico (GPUs) em aplicações científicas, que são voltadas ao desempenho, gerou a necessidade de otimizar os programas que nelas rodam. Uma ferramenta adequada para essa tarefa é o modelo de desempenho que, por sua vez, se beneficia da existência de uma ferramenta de extração de informações de desempenho para GPUs. Este trabalho cobre a criação de um gerador de microbenchmark para instruções PTX que também obtém informações sobre as características do hardware da GPU. Os resultados obtidos com o microbenchmark foram validados atr

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6

Gumbrecht, Rene [Verfasser], and Paul [Akademischer Betreuer] Müller. "Development of customized pTx MR excitation methods and their safe application / Rene Gumbrecht. Gutachter: Paul Müller." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2013. http://d-nb.info/1075474167/34.

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7

Lanctôt, Christian. "Rôle des gènes à boîte homéo de la famille Ptx au cours de l'embryogénèse de la souris." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0009/NQ39757.pdf.

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8

Schneider, Rainer [Verfasser], Jens [Akademischer Betreuer] Haueisen, Jürgen [Akademischer Betreuer] Reichenbach, and Josef [Akademischer Betreuer] Pfeuffer. "Selective Excitation MR Imaging with Parallel Transmission (pTx) / Rainer Schneider. Gutachter: Jürgen Reichenbach ; Josef Pfeuffer. Betreuer: Jens Haueisen." Ilmenau : Universitätsbibliothek Ilmenau, 2015. http://d-nb.info/1072072882/34.

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Schneider, Rainer Verfasser], Jens [Akademischer Betreuer] [Haueisen, Jürgen [Akademischer Betreuer] Reichenbach, and Josef [Akademischer Betreuer] Pfeuffer. "Selective Excitation MR Imaging with Parallel Transmission (pTx) / Rainer Schneider. Gutachter: Jürgen Reichenbach ; Josef Pfeuffer. Betreuer: Jens Haueisen." Ilmenau : Universitätsbibliothek Ilmenau, 2015. http://nbn-resolving.de/urn:nbn:de:gbv:ilm1-2015000033.

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10

Vietta, Giovanna Grünewald. "Caracterização dos níveis da pentraxina-3 (PTX-3) em amostra de pacientes com cardiopatia isquêmica estável na população brasileira." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/17435.

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Introdução: A Pentraxina-3 (PTX-3), produzida principalmente por macrófagos e células da vasculatura endotelial em resposta aos primeiros sinais pró-inflamatórios, tem sido apontada como um novo marcador de eventos coronarianos. Este estudo objetiva caracterizar os níveis plasmáticos de PTX-3 em pacientes com doença arterial coronariana estável em uma população brasileira, bem como sua relação com outros marcadores de risco cardiovascular e manifestação clínica de doença arterial coronariana (DAC). Métodos: Caracterização dos fatores de risco cardiovascular clássicos, e determinação dos níveis

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11

Thiébaut, Stéphanie. "Influence de la duree de stockage sur les proprietes thermodynamiques, structurales et microstructurales des systemes pd 100-(x + y) ptx rhy - t2 (d2)." Paris 6, 1996. http://www.theses.fr/1996PA066709.

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Cette etude a montre que la substitution du palladium par quelques pour-cent atomiques de platine et/ou de rhodium modifie largement les proprietes de stockage du tritium et les phenomenes lies au vieillissement de ces systemes. A l'etat initial, les pressions d'equilibre dependent uniquement du taux de substitution global et pas du tout de la nature des substituants. Au cours du vieillissement, la diminution des pressions de plateaux est plus forte pour les alliages pd-pt, et surtout pour l'alliage ternaire pd#9#0pt#5rh#5. On explique cet effet par une difference du type des defauts crees lor

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12

Friedlander, Jonathan. "Deconstructing the Paxillin-GIT-PIX-PAX complex." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610099.

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13

Haselwarter, Kathrin. "Langzeit-Outcome nach chirurgischer Therapie von pT3- und pT4-Schilddrüsenkarzinomen." kostenfrei, 2008. http://www.opus-bayern.de/uni-regensburg/volltexte/2009/1172/.

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14

Dvořák, Petr. "Porovnání konvenčních PTP a PTN s proudovými a napěťovými senzory." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-400564.

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The diploma thesis deals with conventional transformers and current and voltage sensors. The first half of thesis describes mainly the basic concepts and accuracy classes of these converters used in electrical substations. The emphasis is given primarily on the differences. In the second half of thesis is presented an exact type of converters, which are installed in the substation Medlánky. There is an analysis of measured data from long – term monitoring from this substation and comparing the results from conventional transformers compared to the results from more modern sensors.

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15

Twieg, Michael D. "APPLICATIONS OF GALLIUM NITRIDE FETS TO RF ARRAYS FOR MAGNETIC RESONANCE IMAGING." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1459253932.

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16

Buhl, Stephanie [Verfasser]. "Retrospektive Analyse zum operativen, onkologischen und funktionellen Ergebnis von Patienten mit Nierenzellkarzinom im Stadium pT1/pT2 / Stephanie Buhl." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1160515247/34.

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17

WETZEL, OLIVIER. "Prevention des recidives des tumeurs superficielles de vessie (pta, pt1, ptis) par instillations endovesicales de bcg : 55 patients." Nantes, 1992. http://www.theses.fr/1992NANT126M.

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18

Artico, Fausto. "Performance Optimization Of GPU ELF-Codes." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3424532.

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GPUs (Graphic Processing Units) are of interest for their favorable ratio $\frac{GF/s}{price}$. Compared to the beginning - early 1980's - nowadays GPU architectures are more similar to general purpose architectures but with (much) larger numbers of cores - the GF100 architecture released by NVIDIA in 2009-2010, for example, has a true hardware cache hierarchy, a unified memory address space, double precision performance and has a maximum of 512 cores. Exploiting the computational power of GPUs for non-graphics applications - past or present - has, however, always been hard. Initially, in t

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19

Beije, Gustav. "Pix." Thesis, Mittuniversitetet, Institutionen för informationssystem och –teknologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-36478.

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This thesis is about the creation of a new game framework named Pix and a comparison between it and the game engine Godot. The purpose is to create a game framework that focuses on making the workflow streamlined for the pro- grammer and at the same time giving the programmer a lot of creative power. Pix uses C# as programming language which runs on the .NET Core platform. Pix is built with Entity Component System (ECS) design which means that the design is data-oriented and that it focuses on composition. Thus the ECS design brings with it a clear separation between logic and data. The ECS de

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20

Jallad, Samer. "Biomedical markers of response to intravesical BCG treatment in high-grade non-muscle invasive (PTA and PT1) transitional cell carcinoma of the bladder." Thesis, University of Brighton, 2015. https://research.brighton.ac.uk/en/studentTheses/9dab009b-4eaa-4f3a-a14c-a941f3948ccb.

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Intravesical Bacillus Calmette–Guérin (BCG) immunotherapy is the main treatment for bladder high-grade non-muscle invasive transitional cell carcinoma (HGNMITCC) following initial resection. Unfortunately, about 30% of patients will not respond to treatment and they carry a high risk of disease progression. The alternative, radical cystectomy, has major risks with high morbidity and mortality. The ability to predict the response to BCG treatment would be a useful tool in the selection of appropriate treatment modalities. This study investigated a variety of detectable immune responses in blood

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21

Robison, Heidi Joan. "Phonation Threshold Pressure and Phonation Threshold Flow in Rabbits Treated With Inhaled Corticosteroids Versus Controls." BYU ScholarsArchive, 2021. https://scholarsarchive.byu.edu/etd/8936.

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This thesis is part of a larger series of studies being conducted by Kristine Tanner, PhD, Associate Professor in the Department of Communication Disorders at Brigham Young University (BYU). The larger project is funded by the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health. This thesis primarily investigated the effects of combination inhaled corticosteroids (ICs) on aerodynamic measures of the voice. In recent years, an increase in the localized laryngeal side effects from IC treatment, including dysphonia, have been reported. This study

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22

Jones, Clare Alexa. "Molecular pharmacology of P2X{sub4} and P2X{sub6} receptors for ATP." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620195.

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23

Rodrigues, José Antonio. "Demodulador Argos III compatível com sinais PTT-A2 e PTT-A3." Instituto Nacional de Pesquisas Espaciais (INPE), 2018. http://urlib.net/sid.inpe.br/mtc-m21c/2018/08.01.12.38.

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Atualmente, o alerta prévio de desastres naturais e ambientais iminentes, a previsão acurada do clima e compreensão detalhada do status dos recursos hídricos globais são assuntos cotidianos extremamente importantes para a comunidade global. Os Serviços Nacionais de Meteorologia e Hidrologia em todo o mundo são responsáveis por fornecer essas informações, que são necessárias para a proteção do meio ambiente, desenvolvimento econômico (transporte, energia, agricultura, etc.) e a segurança da vida e da propriedade. Neste contexto, um dos serviços amplamente utilizado mundialmente é o Sistema Inte

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24

Van, Zyl Leonardo Joaquim. "Analysis of the mobilization region of the broad host-range IncQ-like plasmid, pTC-F14, and its ability to interact with a related plasmid, pTF-FC2." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/70109.

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Thesis (MSc)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: The 14.2 kb plasmid pTC-FI4 was isolated from the moderately thermophilic (45°- 50°C), highly acidophilic (pH 1.5 to 2.5), chemolithotrophic bacterium Acidithiobacil/us caldus and has a replicon that is closely related to the promiscuous, broad host-range, IncQ-family of plasmids. The region containing the mobilization genes was sequenced and encoded five Mob proteins and an origin of transfer, which are related to the DNA processing (Tral) region of IncPI plasmids, rather than to the three Mob protein systems of the I

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25

Tonon, Sandrine. "La toxine de Bordetella pertussis active les cellules dendritiques et les lymphocytes T CD4 naïfs chez l'homme." Doctoral thesis, Universite Libre de Bruxelles, 2006. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210749.

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La toxine de pertussis (PTX) est une A-B protéine considérée comme l’un des principaux facteurs de virulence de Bordetella pertussis, l’agent bactérien responsable de la coqueluche. Aujourd’hui, cette maladie représente encore un réel danger pour les nouveaux-nés et les<p>nourrissons non ou partiellement immunisés. Actuellement, la coqueluche provoque encore la<p>mort d’environ 350.000 individus par an. La toxicité de la PTX est liée à l’activité<p>enzymatique de sa sous-unité A capable d’inhiber les voies de signalisation associées aux<p>protéines Gi. La partie B, quant à elle, permet l’entré

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26

Grenier, Denis. "De la Pax Romana à la Pax Senensis : Ambrogio Lorenzetti et l'Antiquité." Master's thesis, Université Laval, 1993. http://hdl.handle.net/20.500.11794/17657.

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Faust, Eberhard. "Pax Christi et Pax Caesaris : religionsgeschichtliche, traditionsgeschichtliche und sozialgeschichtliche Studien zum Epheserbrief /." Freiburg : Göttingen : Schweiz : Universitätsverlag ; Vandenhoeck & Ruprecht, 1993. http://catalogue.bnf.fr/ark:/12148/cb355768183.

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Alhabashneh, Mohammad Abad Alhameed. "Protect team handler (PTH)." Thesis, University West, Department of Technology, Mathematics and Computer Science, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-567.

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<p>There is always a need for easy-to-follow processes that enable accurate and non-time consuming solutions. Nowadays we see a lot of different approaches to development processes in software engineering. This project is concerned with how to manage a software development process in a reliable, secure and efficient way. Software is available which provides some help for project managers / administrators to work more productively, with effective communication. Using such systems, it is possible to keep track of all the phases of development, including task distribution, making maximum use of p

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29

Borden, J. Benjamin. "New-fangled copper pox /." Available to subscribers only, 2007. http://proquest.umi.com/pqdweb?did=1328049371&sid=17&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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30

Simmler, Urs. "PTC Creo Simulate 3.0." Universitätsbibliothek Chemnitz, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-171761.

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31

Büttner, Rene. "PTC Mathcad Prime 3.1." Universitätsbibliothek Chemnitz, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-172536.

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Wüst, Michael, and Steffen Förster. "PTC Mathcad Prime : Überblick." Universitätsbibliothek Chemnitz, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-142117.

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33

Agarwal, Asit. "PTC Creo Simulate updates." Technische Universität Chemnitz, 2018. https://monarch.qucosa.de/id/qucosa%3A21379.

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34

Vilímek, Hynek. "Převod PPTX do HTML." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2016. http://www.nusl.cz/ntk/nusl-255407.

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PowerPoint is an excellent tool for creating presentations and people are accustomed to using it. Its only handicap is that it is not installed everywhere and it exists in numerous versions. But there is an application that is installed almost everywhere and that application is the web browser. This work aims to create the PowerPoint presentation viewer for the web browser. With the internet as the environment, it may have a wide range of applications from the content sharing point of view. The solution is a web application that allows to upload the PowerPoint file and then the application dis

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35

Maxwell, Megan Amanda, and n/a. "PEX1 Mutations in Australasian Patients with Disorders of Peroxisome Biogenesis." Griffith University. School of Biomolecular and Biomedical Science, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040219.100649.

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The peroxisome is a subcellular organelle that carries out a diverse range of metabolic functions, including the b-oxidation of very long chain fatty acids, the breakdown of peroxide and the a-oxidation of fatty acids. Disruption of peroxisome metabolic functions leads to severe disease in humans. These diseases can be broadly grouped into two categories: those in which a single enzyme is defective, and those known as the peroxisome biogenesis disorders (PBDs), which result from a generalised failure to import peroxisomal matrix proteins (and consequently result in disruption of multiple metab

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Maxwell, Megan Amanda. "PEX1 Mutations in Australasian Patients with Disorders of Peroxisome Biogenesis." Thesis, Griffith University, 2004. http://hdl.handle.net/10072/366184.

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The peroxisome is a subcellular organelle that carries out a diverse range of metabolic functions, including the b-oxidation of very long chain fatty acids, the breakdown of peroxide and the a-oxidation of fatty acids. Disruption of peroxisome metabolic functions leads to severe disease in humans. These diseases can be broadly grouped into two categories: those in which a single enzyme is defective, and those known as the peroxisome biogenesis disorders (PBDs), which result from a generalised failure to import peroxisomal matrix proteins (and consequently result in disruption of multiple metab

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37

Simmler, Urs. "Mechanism-News in PTC Creo." Universitätsbibliothek Chemnitz, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-141525.

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Der Vortrag gibt einen Überblick der Neuerungen im Werkzeug Mechanism der Creo Versionen 1.0 und 2.0. Zudem werden 10 hilfreiche "Tips und Tricks" vorgestellt, welche den Mechanismuseinsatz vereinfachen.

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Sibley, David N. "Viscoelastic flows of PTT fluid." Thesis, University of Bath, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518114.

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Ormond, Susan Jane. "Trafficking of heteromeric P2X purinoreceptors." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614886.

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Hibell, Amanda Dawn. "Functional characteristics of P2X₇ receptors." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621665.

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Alhabashneh, Mohammad Abad Alhameed. "Project and team handler (PTH)." Thesis, Högskolan Väst, Institutionen för teknik, matematik och datavetenskap, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-567.

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There is always a need for easy-to-follow processes that enable accurate and non-time consuming solutions. Nowadays we see a lot of different approaches to development processes in software engineering. This project is concerned with how to manage a software development process in a reliable, secure and efficient way. Software is available which provides some help for project managers / administrators to work more productively, with effective communication. Using such systems, it is possible to keep track of all the phases of development, including task distribution, making maximum use of prev

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42

Coronado, Jose. "PTC Creo Simulate 4 Roadmap." Universitätsbibliothek Chemnitz, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-206764.

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Roberts, Arwel W. "BaTiO₃ ceramics for PTC applications." Thesis, Durham University, 1994. http://etheses.dur.ac.uk/1428/.

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Chavan, Arun T. "PTC CREO SIMULATE ENGINE UPDATES." Universitätsbibliothek Chemnitz, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-225870.

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Zheng, Wenxuan. "Properties of mammalian P2X₇ receptors." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/properties-of-mammalian-p2x7-receptors(1ff23f4a-47eb-4d06-b54c-bd7488c9700c).html.

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To establish comprehensive pharmacology of P2X₇ receptors, membrane current recording, intracellular calcium transient recording and ethidium bromide uptake were carried out to examine several selective (A-740003, A- 438079) and non-selective (suramin) P2X₇ antagonists across mammalian P2X₇ receptors (human, mouse and rat). These P2X₇ receptors demonstrated species-dependent sensitivities to antagonists. In each species, A-740003 revealed variant IC50 values with different assays, indicating the assay- dependent pharmacology of P2X₇ receptors. Conventionally, pharmacology can be used to define

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46

Silva, Villablanca Oscar. "Puerto terrestre de Casablanca : PTC." Tesis, Universidad de Chile, 2006. http://repositorio.uchile.cl/handle/2250/100956.

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Vlk, Bronislav. "Možnosti videokonferencí v PBX Asterisk." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219738.

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This thesis deals with the possibilities of video conferencing in Asterisk PBX and their use in practice. They also described the contingencies and how its configuration. Particular attention is paid to the protocols SIP, IAX and H.323, which are described in one of the chapters. The thesis was created by the Asterisk PBX, which demonstrates cooperation with videoconferencing clients. The thesis describes the configuration files so that the central set. Conclusion the work assesses the use of codecs for different clients.

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Selldén, Magnus. "Estimering av laster på PTO-kraftuttag." Thesis, Linköpings universitet, Fordonssystem, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-68660.

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För att utöka ett fordons användningsområde kan det utrustas med olika typer av arbetsredskap och lasthanteringsutrustning. För att driva dessa finns möjlighet till kraftuttag (PTO - Power Take-Off) från ett antal anslutningar vid motor och drivlina. I dagsläget saknar motorns styrsystem information om dessa laster vilket kan påverka styrningen negativt. I detta arbete presenteras en metod för att estimera det okända lastmomentet på kraftuttaget. Metoden utgår från Newtons andra lag för svänghjulet och det drivande momentet till drivlinan beskrivs av en dynamisk modell. Genom att beräkna hur m

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Straukaitė, Erika. "UAB "PTA Group" vartotojų lojalumo tyrimas." Bachelor's thesis, Lithuanian Academic Libraries Network (LABT), 2010. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100903_001321-49819.

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SANTRAUKA Bakalauro baigiamajame darbe pateikiama užsienio ir lietuvių autorių suformuotos vartotojų lojalumo sampratos ir esmė, atskleisti ir analizuojami vartotojų lojalumą formuojantys veiksniai, lojalių klientų nauda įmonei, nagrinėjami lojalumo tipai ir lojalumo matavimo metodai. Remiantis išanalizuota literatūra lojalumo formavimo aspektu ir naudojantis lojalumo ekspertų F. Reicheldo bei J. J. Ellingo ir S. Jorgenseno lojalumo matavimo metodais atlikta UAB „PTA Group“ vartotojų lojalumo analizė. Šio bakalauro sudedamosios dalys: 1. vartotojų lojalumo sampratų, formavimo, naudos ir mata

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Rolf, Michael George. "P2X₁ receptors and human platelet function." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621241.

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