Artykuły w czasopismach na temat „Province of Quebec Association of Architects”

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Hendri, Hendri, Rahma Evita Chaniago, Robihtho Dhia Shidqi, Dianny Putri Ramli i Rahdiansyah Rahdiansyah. "PENGATURAN PRAKTEK LAYANAN PROFESI ARSITEK ATAS ARSITEK ILEGAL DI PROVINSI RIAU". Mizan: Jurnal Ilmu Hukum 12, nr 2 (6.12.2023): 144. http://dx.doi.org/10.32503/mizan.v12i2.4476.

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The primary objective of this research is to examine the role of the architectural professional organization, namely the Indonesian Architects Association (IAI), in supervising the practices and services of the architectural profession in Riau Province. This research also aims to understand the problems related to illegal architects that occur in Riau Province and analyze the application of sanctions and solutions by IAI Riau Province to this problem. This research uses a normative juridical method which examines the implementation of positive legal provisions in each specific legal event that occurs in society, data obtained from interviews with related parties. IAI Riau has taken various efforts to supervise and develop professional architect service practice providers. This effort includes preventive and curative measures. To provide education to prospective architects regarding the applicable legal rules of the architectural profession. Apart from that, curative efforts are carried out by providing sanctions for violations of the professional code of ethics. Apart from that, IAI Riau Province also took a persuasive approach to the Provincial Government and the PUPR Service. This approach aims to align common goals and ensure that Undang-Undang No 6 of 2017 concerning architects can be fully enforced in the Riau Province Region. It is hoped that this research will provide better insight into how the regulation of architectural professional service practices can deal with the problem of illegal architects in Riau Province and optimize the role of IAI in overcoming this challenge.
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Guttman, Renata. "Architecture in Canada: French-language publishing, 1981-1995". Art Libraries Journal 21, nr 3 (1996): 4–28. http://dx.doi.org/10.1017/s0307472200009949.

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Interest in Canada’s built heritage flourished in the period following 1967, inspired by the centennial of Confederation and institutional support of heritage research. An already vibrant and officially sanctioned concern for cultural history in Canada’s mainly Francophone province Quebec and the Official Languages Act of 1969 resulted in a rich series of French-language publications devoted to Canadian architecture. The architecture of provinces, cities and towns, of individual styles, buildings and architects, architectural competitions and archaeology have all been explored in the literature. The contribution of scholars, cultural, academic, and governmental institutions, and publishers has created a strong body of work related to architecture in Canada.
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Ladouceur, Robert. "Prevalence Estimates of Pathological Gambling in Quebec". Canadian Journal of Psychiatry 36, nr 10 (grudzień 1991): 732–34. http://dx.doi.org/10.1177/070674379103601007.

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Pathological gambling was officially defined and recognized as a psychiatric illness by the American Psychiatric Association in 1980. This survey reports the results of a province-wide study in Quebec based on telephone interviews using standardized assessment instruments with 1,002 subjects. The current prevalence of pathological gambling is 1.2%. The results also show that 88% of the respondents have gambled at least once in their life. The implications of these results for the prevention and treatment of this debilitating disorder are discussed.
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Sexton, Jean. "Controlling Corruption in the Construction Industry: The Quebec Approach". ILR Review 42, nr 4 (lipiec 1989): 524–35. http://dx.doi.org/10.1177/001979398904200404.

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Between 1968 and 1975, the Province of Quebec instituted several laws to combat violence and corruption in its construction industry. Among them were a requirement that all construction workers belong to a union, and all contractors to the sole employers' association; province-wide coverage of construction workers and employers by a single collective agreement at any given time; the presumption of guilt of anyone charged with criminal activities in the industry; mandated multiple sources of manpower, to prevent monopolies in manpower allocation; mandatory elections of union stewards, to prevent abuses by appointed stewards; the barring from union office of those with criminal records; and government trusteeship of several union locals. The author credits these measures with dramatically reducing violence and corruption, but cautions that they might not be readily transferable to labor relations systems outside Quebec.
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Gagné, Thierry, Annie Pelekanakis i Jennifer L. O’Loughlin. "Do demographic and socioeconomic characteristics underpin differences in youth smoking initiation across Canadian provinces? Evidence from the Canadian Community Health Survey (2015–2018)". Health Promotion and Chronic Disease Prevention in Canada 42, nr 11/12 (listopad 2022): 457–65. http://dx.doi.org/10.24095/hpcdp.42.11/12.01.

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Introduction Youth initiation may drive differences in smoking prevalence across Canadian provinces. Provincial differences in initiation relate to tobacco control strategies and public health funding, but have also been attributed to population characteristics. We test this hypothesis by examining the extent to which seven characteristics—immigration, language, family structure, education, income, home ownership and at-school status—explain differences in initiation across provinces. Methods We used data from 16 897 youth aged 12 to 17 years in the Canadian Community Health Survey collected from 2015 to 2018. To examine the proportion of provincial differences explained by population characteristics, we compared average marginal effects (AMEs) from partially and fully adjusted models regressing “having ever initiated” on province and other characteristics. We also tested interactions to examine differences in the association between population characteristics and initiation across provinces. Results Initiation varied from 4% in British Columbia to 10% in Quebec. Being born in Canada, speaking French, not living in a two-parent household, being in the lowest household income quintile, having parents without postsecondary education, living in rented accommodation and not being in school were each associated with initiation. Taking these results into consideration, the AME of residing in another province compared with Quebec was attenuated by between 3% and 9%. Family structure and household income were more strongly associated with initiation in the Atlantic region and Manitoba, but not in Quebec. Conclusion Differences in initiation between Quebec and other provinces are unlikely to be substantially explained by their demographic or socioeconomic composition. Reprioritizing tobacco control and public health funding are likely key in attaining the “tobacco endgame” across provinces.
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Cutumisu, Nicoleta, Issouf Traoré, Marie-Claude Paquette, Linda Cazale, Hélène Camirand, Benoit Lalonde i Eric Robitaille. "Association between junk food consumption and fast-food outlet access near school among Quebec secondary-school children: findings from the Quebec Health Survey of High School Students (QHSHSS) 2010–11". Public Health Nutrition 20, nr 5 (24.11.2016): 927–37. http://dx.doi.org/10.1017/s136898001600286x.

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AbstractObjectiveWe investigated the association between junk food consumption at lunchtime (JCL) and fast-food outlet access near school among secondary-school children in Quebec.DesignA geographic information system database was used to characterize the food environment around a sub-sample of 374 public schools in which 26 655 students were enrolled. The outcome variable was JCL during the previous week, dichotomized into low JCL (none or once)v. high JCL (twice or more). Access to fast-food outlets near school was assessed using an existing database of fast-food outlets in Quebec. Covariates included student (age, sex and self-rated perceived health), family (familial status and parental education) and school (urban/rural status and deprivation) variables. Hierarchical logistic regression models were employed for analyses using PROC GLIMMIX of SAS version 9.3.SettingProvince of Quebec, Canada.SubjectsWe used data from the Quebec Health Survey of High School Students (QHSHSS) 2010–11, a survey of secondary-school Quebec students.ResultsExposure to two or more fast-food outlets within a radius of 750 m around schools was associated with a higher likelihood of excess JCL (OR=1·50; 95 % CI 1·28, 1·75), controlling for the characteristics of the students, their families and their schools.ConclusionsThe food environment surrounding schools can constitute a target for interventions to improve food choices among secondary-school children living in the province of Quebec. Transforming environments around schools to promote healthy eating includes modifying zoning regulations that restrict access to fast-food outlets around schools.
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Ngamini Ngui, André, Philippe Apparicio, Mathieu Philibert i Marie-Josée Fleury. "Neighborhood Characteristics Associated with the Availability of Alcohol Outlets in Quebec, Canada". Journal of Addiction 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/876582.

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Objectives. The objectives of this study were to examine the spatial accessibility to alcohol outlets in Quebec and to assess the association between neighborhood level characteristics and availability of alcohol outlets.Methods. The Tobit Model was used to assess the association between neighborhood level characteristics and the availability of alcohol outlets within 500, 1000, 2000, and 3000 metres, respectively.Results. Alcohol outlets were found to be most available in the two largest metropolitan areas of the province of Quebec (Montréal and Québec City). Within 1000 metres, alcohol outlets are more available in neighbourhoods with the following characteristics: highest concentration of men, least materially deprived highest concentration of persons aged 20 years or more, and location either in a metropolitan area or in a small town. Finally, the number of bars with video lottery terminals increases with the level of social and material deprivation.Conclusion. In Québec, there is no rule governing the location of alcohol outlets. Thus, there is an abundant literature indicating that the regulation of alcohol outlet density could be an effective means of controlling risk attributable to alcohol consumption.
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Castonguay, Mathias, Nawar Dakhallah, Marie-Laure Colaiacovo, Camille Jimenez-Cortes, Justin Desroches, Anne-Marie Claveau, Amer Yassine Hafsaoui i in. "COVID-19 and Sickle Cell Disease in the Province of Quebec: Morbidity and Mortality Rates Derived from the Provincial Registry". Blood 138, Supplement 1 (5.11.2021): 4064. http://dx.doi.org/10.1182/blood-2021-151361.

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Abstract Introduction Approximately 1500 people live with sickle cell disease (SCD) in the province of Quebec, Canada. Public health has recognized these patients as immunocompromised. SCD patients may be at higher risk of developing severe COVID-19 infection due to their underlying pro-inflammatory and thrombogenic state, splenic dysfunction and secondary organopathies. Descriptions about disease severity and mortality rates in SCD vary widely. From the SECURE-SCD registry, Mucalo et al. recently reported a 0.3% and 4.7% mortality rate in children and adults, respectively. In the French registry, Arlet and colleagues reported a 2.4% death rate among those hospitalized with COVID-19 and SCD, not different from the general population. As a result, the COVID-19 morbidity and mortality rates among the SCD population remain uncertain. Objectives The primary objectives of our study are to describe the epidemiology, baseline characteristics and clinical outcomes of SCD patients with COVID-19 infection in the province of Quebec. In addition, we aim to identify risk factors for hospitalization and severe forms of COVID-19. Methods We built a web-based SCD-COVID-19 registry regrouping 7 adult and 4 paediatric tertiary care hospitals in the province of Quebec in June 2020. All SCD patients with a confirmed SARS-CoV-2 infection by PCR test were included in the study. We compared the prevalence of infection and hospitalization rates of SCD patients to the general population of Quebec using the epidemiological data from the INSPQ (National Institute of Public Health of Quebec) public database. We retrospectively analyzed data included between March 11, 2020 to March 1, 2021. Relative risk was calculated using bilateral association measures (exact fisher, mid-p or chi-squared tests, as appropriate) to compare the incidence of infection and hospitalization of SCD patients to the population of Quebec and to assess risk factors of hospitalization among SCD patients. Results During the first 12 months of the pandemic, 74 patients were included in the registry. The male to female ratio was 1:1.12. Median age was 23 years, ranging from 8 months to 68 years old. SS-Sbeta 0 genotypes were present in 51% of cases, while 49% were SC or Sbeta +. The majority of patients were on disease modifying therapy: 54% were on hydroxyurea and 17.5% on exchange transfusion therapy. The incidence of reported COVID-19 infection was significantly higher in SCD patients compared to the general population (4.9% vs. 3.5% p=0,002) (Table 1). Even more strikingly, SCD had rate of hospitalization 10-times greater than the general population (33.8 vs 3.2%, p<0,001). Nevertheless, the risk of admission to the intensive care unit was similar between SCD patients and the general population (24.0% vs. 24.1%, p=0.99). No death was recorded amongst SCD patients with COVID-19 compared to a death rate in the general population in Quebec of less than 70 years old of 48-78 for 100 000 infections (male-female). A history of acute chest syndrome (ACS) in the last year (OR 2.6 [1.5-4.6], p=0.04) and arterial hypertension (OR 3.3 [2.3-4.8], p=0.01) were associated with a higher risk of hospitalization (Table 2). On the other hand, there was no statistically significant association with age, sex, genotype, ABO blood group, baseline SCD therapy, or other comorbidities (chronic renal disease, obesity, pulmonary hypertension, chronic lung disease and previous admission to ICU) in our cohort. Conclusions Similar to other reports, we found that SCD patients were at much greater risk of hospitalization compared to the general population. We however found no increased risk of mortality or disease complication. This contrasts with results from other registries. A history of ACS and hypertension were associated with a higher risk of hospitalization. Whether social determinants of health could explain some of the outcome variability between different countries merit further investigation. Furthermore, we believe that registries are critical to monitor the impact of preventive measures. As vaccination is ongoing, it will be important to consider its impact on hospitalization and death rate among SCD population. Recruitment to the registry is ongoing and updated data will be presented at the meeting. Figure 1 Figure 1. Disclosures Soulieres: BMS: Membership on an entity's Board of Directors or advisory committees; Novartis: Research Funding. Forté: Novartis: Honoraria; Canadian Hematology Society: Research Funding; Pfizer: Research Funding.
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Wardle, Richard J., Donald T. James, David J. Scott i Jeremy Hall. "The southeastern Churchill Province: synthesis of a Paleoproterozoic transpressional orogen". Canadian Journal of Earth Sciences 39, nr 5 (1.05.2002): 639–63. http://dx.doi.org/10.1139/e02-004.

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The Paleoproterozoic southeastern Churchill Province (SECP) is located in the northeastern Canadian Shield of Labrador and Quebec. The SECP formed through the oblique collisions of the Archean Nain and Superior cratons with a third intervening Archean block, the core zone. The belt has a tripartite structure, comprising the Torngat Orogen (TO) formed by Nain craton – core zone collision in the east, the core zone in the centre, and the New Quebec Orogen (NQO) formed by Superior craton – core zone collision in the west. The SECP thus records transpressional development on the flanks of the Superior and Nain cratons as they indented northwards to form the larger Trans-Hudson – Nagssugtoqidian orogenic belt to the north. Principal stages of tectonic development were (1) 2.2–2.1 Ga crustal rifting of Nain and Superior cratons; (2) ca. 1.9 Ga subduction under eastern Nain craton; (3) ca. 1.87–1.85 Ga collision of Nain craton and core zone to form the TO; (4) 1.845–1.820 Ga sinistral transpression in the TO, and subduction under the western core zone; and (5) 1.82–1.77 Ga collision of Superior craton and core zone to form the NQO, in association with dextral transpression. Crustal-scale cross sections of the SECP have been developed from reflection and refraction seismic data. The western part of the NQO is dominantly west-vergent and associated with an imbricate thick-skinned thrust stack that ramps from the base of the crust. The core zone is characterized by a 35–40 km thick crust and pervasive east-dipping fabrics related to westerly thrusting. The TO is a narrow, doubly vergent belt, associated with a 48 km thick crust that forms a crustal root with a Moho relief of 12 km. The root is interpreted to result from attempted subduction of the core zone under the Nain craton, possibly as a result of mid-crustal wedging by the Nain craton. The TO was the site of intense convergence that resulted in excision of juvenile crust, possibly including tectonic removal of the axial magmatic arc. As a result, the middle to lower levels of the SECP consist largely of refractory Archean lithosphere. This may account for the lack of widespread post-collisional plutonism in the SECP and the preservation of the TO root.
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Poder, Thomas G., Liang Wang i Nathalie Carrier. "EQ-5D-5L and SF-6Dv2 utility scores in people living with chronic low back pain: a survey from Quebec". BMJ Open 10, nr 9 (wrzesień 2020): e035722. http://dx.doi.org/10.1136/bmjopen-2019-035722.

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ObjectiveTo describe how chronic low back pain (CLBP) impacts on utility scores and which patients’ characteristics most affect these scores in the province of Quebec.SettingsProvince of Quebec, Canada.Participants569 adult patients with CLBP.Methods and outcomesAn online survey on low back pain was conducted between October 2018 and January 2019. The EuroQol Five Dimensions (EQ-5D-5L) and the Short Form Six Dimensions version 2 (SF-6Dv2) are two generic preference-based measures used to evaluate health-related quality of life (HRQoL) and provide quality-adjusted life-year utility values.ResultsThe number of subjects who agreed to participate was 610, but 41 were excluded because 8 had low back pain for less than 3 months and 33 did not start the survey. A total of 569 subjects were analysed, but only 410 completed the survey up to the EQ-5D-5L or SF-6Dv2 sections. Median (range) of EQ-5D-5L was 0.622 (−0.072 to 0.905), and mean (range) of SF-6Dv2 and EQ-Visual Analogue Scale was 0.561 (0.301–0.829) and 51.0 (0–100), respectively. In all multivariate models, health or life satisfaction increased the health utility score, while pain reduced it. Co-occurring health problems were present for a majority (68%) of participants, mainly fatigue/insomnia (57.4%), musculoskeletal disorder (56.2%) and mental disorder (44%).ConclusionThis study provided utility scores with EQ-5D-5L and SF-6Dv2 in patients with CLBP in Quebec, and results were similar to other studies conducted in different settings. These values were well below those reported in the Quebec general population and highlight the association between CLBP and HRQoL.
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Morin, Diane, i Virginie Cobigo. "Reliability of the Supports Intensity Scale (French Version)". Intellectual and Developmental Disabilities 47, nr 1 (1.02.2009): 24–30. http://dx.doi.org/10.1352/2009.47:24-30.

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Abstract The definition of intellectual disability, according to the American Association on Intellectual and Developmental Disabilities, includes the assumption that adequate supports should improve a person's functioning. Consequently, support needs have to be assessed to plan services for persons with intellectual disability. The Supports Intensity Scale (SIS; J. R. Thompson et al., 2004) is a standardized instrument for assessing support needs and their intensity. This study was designed to estimate the interrespondent, interinterviewer coefficients of the French version of the SIS. Approximately 40 persons with intellectual disabilities from Quebec, a Canadian province, participated in this study. For each participant, 2 respondents and 2 interviewers were identified and 3 French SIS questionnaires were filled out. Results are presented and discussed compared with those obtained with the original, English-based SIS.
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Klose, Glen, Colleen Mooney i Doug McLeod. "Re-integration: a new standard in first responder peer support". Journal of Community Safety and Well-Being 2, nr 2 (28.06.2017): 55. http://dx.doi.org/10.35502/jcswb.47.

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Since its inception, the Edmonton Police Service (EPS) Re-integration Program has grown in its capacity, impact, and service to members within EPS. It has also attracted increasing attention among—and emulation by—other first responder communities in the province of Alberta. Most recently, the program was the subject of a featured segment during the joint Canadian Association of Chiefs of Police (CACP) and Mental Health Commission of Canada (MHCC) international conference, “The Mental Health of Police Personnel: What We Know & What We Need to Know and Do”, held in February 2017. Based on the strong reception and interest generated among conference delegates, the Journal of CSWB invited the program’s architects to develop the following Practice Guideline article, with a view to bringing wider awareness to this unique peer-supported program. The EPS program connects conventional counselling and support resources with aspects of recovery and re-integration that are more closely tied to the equipment and operational realities of first responders.
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Roy, Carmella A., Mark Zoccolillo, Reut Gruber, Michel Boivin, Daniel Pérusse i Richard E. Tremblay. "Construct Validity of an Instrument to Assess Major Depression in Parents in Epidemiologic Studies". Canadian Journal of Psychiatry 50, nr 12 (październik 2005): 784–91. http://dx.doi.org/10.1177/070674370505001208.

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Objective: The Longitudinal Study of Child Development in Quebec (LSCDQ) is a community study of children that examines the risk factors, such as parental depression, linked to childhood psychopathology and maladaptive functioning. Our goal was to test the construct validity of an instrument to assess major depression in the parents. Method: Parents of a representative sample of 2120 infants born in the province of Quebec in 1998 were selected. The major depression instrument was administered to the parents when the infants were aged 29 months. We tested the construct validity of the instrument by examining 1) sex differences in symptoms and prevalence, 2) the rank order of the prevalence of symptoms, 3) the clustering of symptoms, and 4) the association of depression with functional impairment and treatment-seeking behaviour. Results: Depression was twice as common in mothers as in fathers. Most mothers and fathers who reported ever being depressed for 2 or more weeks had also experienced at least 4 additional depression symptoms. The rank order of symptom prevalence was comparable to that found in other studies. At least 50% of parents reported having talked to a professional and that suffering from depression had interfered with their functioning. Conclusions: The expected sex differences, the rank order of symptom prevalence, the symptom clustering, and the associations with functional impairment and treatment-seeking behaviour support the construct validity of a brief questionnaire on parental major depression.
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Wang, Caroline H.-Y., Christine Loignon i Catherine Hudon. "Uncovering social and psychosocial health factors through participatory qualitative research with low-income adults in a suburb of Montreal, Quebec". BMJ Open 10, nr 2 (luty 2020): e030193. http://dx.doi.org/10.1136/bmjopen-2019-030193.

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ObjectivesThe association between social status and health is well established, but the psychosocial factors and mechanisms underlying this association are not fully understood. This study aims to identify and describe social and psychosocial factors that may harm the health of low-income adults.DesignParticipatory qualitative research using a problem-posing method based on Freire’s pedagogy.SettingCommunity organisation in a low-income district in the metropolitan area of Montreal, in the province of Quebec, Canada.ParticipantsEight low-income adults using food bank services provided by the community organisation. Participants had to reside in the community organisation’s service area, have insufficient income to cover living expenses, be aged 18 years or older, and be able to participate in group sessions.MethodsEight weekly group sessions (average of 2.5 hours per session) were held using problem-posing method, which included activities such as presentation of representative stories or images and role-playing. Five additional sessions were held for thematic data analysis with participants.ResultsA main factor identified as harming the health of participants was the dissonance between perceived current circumstances and the ideal of circumstances conceived early in life. This dissonance follows a loss or a failure to achieve the ideal of circumstances and generates profound malaise. Other main factors identified were the current circumstances as a social trap and the lack of love and support from an early age.ConclusionsThis study identifies a new psychosocial factor, namely, the dissonance between perceived current circumstances and the ideal of circumstances conceived early in life. Larger studies should examine the influence of this factor on health.
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Auger, Nathalie, Caroline Quach, Jessica Healy-Profitós, Anne-Marie Lowe i Laura Arbour. "Congenital microcephaly in Quebec: baseline prevalence, risk factors and outcomes in a large cohort of neonates". Archives of Disease in Childhood - Fetal and Neonatal Edition 103, nr 2 (4.07.2017): F167—F172. http://dx.doi.org/10.1136/archdischild-2016-311199.

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ObjectiveWe assessed baseline prevalence, risk factors and outcomes of microcephaly in a large population of neonates.DesignRetrospective cohort study.SettingAll hospitals in the province of Quebec, Canada.Participants794 microcephalic and 1 944 010 non-microcephalic infants born between 1989 and 2012.Main outcome measuresBaseline prevalence of microcephaly and occurrence of other congenital anomalies. We estimated the association of (1) pregnancy risk factors including TORCH infections (toxoplasmosis, rubella, cytomegalovirus, herpes, other), exposure to teratogens, diabetes and maternal congenital anomalies with risk of microcephaly, and (2) microcephaly with risk of infant mortality and severe morbidity, adjusted for maternal characteristics.ResultsThe overall prevalence of microcephaly was 4.1 per 10 000, ranging between 3.0 and 5.3 per 10 000 over time. Only 37% of microcephalic infants presented with other congenital anomalies. Maternal infection during pregnancy was the strongest risk factor, with 32 times the risk of microcephaly (prevalence ratio 32.38; 95% CI 22.42 to 46.75) compared with no infection. Exposure to teratogens was the next most important risk factor, with three times greater risk (prevalence ratio 3.10; 95% CI 2.37 to 4.07). Microcephaly was associated with 20 times the risk of infant mortality compared with no microcephaly (prevalence ratio 20.52; 95% CI 15.57 to 27.04) and significantly greater infant morbidity.ConclusionsIn Canada, infectious exposure during pregnancy is a strong risk factor for microcephaly, and affected infants are at higher risk of poor birth outcomes. Better monitoring of microcephaly is needed in the event that Zika or other novel viruses affect future risk.
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Carbonneau, Elise, Benoît Lamarche, Véronique Provencher, Sophie Desroches, Julie Robitaille, Marie-Claude Vohl, Catherine Bégin i in. "Associations Between Nutrition Knowledge and Overall Diet Quality: The Moderating Role of Sociodemographic Characteristics—Results From the PREDISE Study". American Journal of Health Promotion 35, nr 1 (9.06.2020): 38–47. http://dx.doi.org/10.1177/0890117120928877.

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Purpose: To assess how nutrition knowledge is associated with global diet quality and to investigate whether sociodemographic characteristics (ie, sex, age, education, income, marital status, and living with children or not) moderate this association. Design: Cross-sectional web-based study. Participants: The PREDISE study aims at identifying correlates of adherence to healthy eating guidelines in French-speaking adults from the Province of Quebec, Canada. Subjects: A probability sample of 1092 participants (50% female). Measures: The Nutrition Knowledge Questionnaire and 24-hour food recalls from which the Canadian Healthy Eating Index (C-HEI) was calculated. Analysis: Multiple linear regressions performed to assess how nutrition knowledge is associated with the C-HEI. Interaction terms tested to evaluate whether sociodemographic characteristics moderate the association between nutrition knowledge and the C-HEI. Results: Nutrition knowledge (B = 0.141 [95% CI: 0.075-0.208], P < .0001) was identified as a significant correlate of the C-HEI. Education significantly moderated the association between nutrition knowledge and the C-HEI ( P interaction = .0038), with a significative association among participants with a lower education level (B = 0.295 [95% CI: 0.170-0.421], P < .0001) but not among participants with a higher education level (B = 0.077 [95% CI: −0.004 to 0.157], P = .06). Whether participants lived with or without children also significantly moderated the association ( P interaction = 0.0043); nutrition knowledge was associated with the C-HEI only in participants who were not living with children (B = 0.261 [95% CI: 0.167 to 0.355], P < .0001). Conclusion: This study suggests that the association between nutrition knowledge and adherence to healthy eating guidelines is not the same in different subgroups of the population. Interventions aiming at increasing nutrition knowledge may be a promising approach to improve diet quality, especially among individuals with a lower education.
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Rochefort, Sophie, Yves Desjardins, David J. Shetlar i Jacques Brodeur. "Establishment and Survival of Endophyte-infected and Uninfected Tall Fescue and Perennial Ryegrass Overseeded into Existing Kentucky Bluegrass Lawns in Northeastern North America". HortScience 42, nr 3 (czerwiec 2007): 682–87. http://dx.doi.org/10.21273/hortsci.42.3.682.

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Overseeding of tall fescue and perennial ryegrass into pre-existing stands of kentucky bluegrass is viewed as a strategy to enhance the quality and durability of turfgrass lawns. In a 3-year study, the authors investigated the winter survival and establishment of tall fescue (‘Bonsai 2000’), with or without Neotyphodium coenophialum, and perennial ryegrass (‘Palmer III’), with or without N. lolii, in the province of Quebec, Canada (≈lat., 54ºN), a region characterized by rigorous winter conditions. Grass species were overseeded in June 2003 at two different rates (90 and 180 kg·ha−1), in experimental plots from two bioclimatological conditions: Quebec City and Boucherville. Turfgrass establishment and endophyte infection were evaluated during the following two spring and fall periods. Both tall fescue and perennial ryegrass had the capacity to establish and survive winter conditions, but performed best when snow cover was thick and present throughout the winter. The proportion of overseeded plants in the turfgrass stand rarely reached 30% over the years. Although the proportion of tall fescue and perennial ryegrass plants was much reduced in the spring, some tillers survived and were able, later in the season, to compete with kentucky bluegrass as tall fescue and perennial ryegrass populations returned to initial establishment populations each summer in mixed stands. Overwinter endophyte survival was species specific, with N. lolii being able to survive the cold winter but not N. coenophialum, which had a low percent of infection. For the perennial ryegrass–N. lolii association, competition with kentucky bluegrass is a primary factor limiting the increase over time in the proportion of endophyte-infected plants in a turfgrass mixture. Seeding rates did not influence the establishment of either grass species.
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MARTINEZ, JOHN LASER M. "EFFICIENCY OF HUMAN RESOURCES MANAGEMENT IN THE CONSTRUCTION INDUSTRIES IN CEBU". Cognizance Journal of Multidisciplinary Studies 3, nr 8 (30.08.2023): 352–534. http://dx.doi.org/10.47760/cognizance.2023.v03i08.011.

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The research was conducted at Cebu Contractors Association, Cebu Province, Philippines in order to implement the efficiency of Human Resources Management in the construction industries in Cebu during Fiscal Year 2021. The efficiency of Human Resources Management in the construction industries in Cebu was evaluated on the effectiveness of its Planning, Leading, Organizing and Controlling, and evaluation. Qualitative method particularly survey research was employed on this study. Questionnaires were given to 20 Human Resource Management Personnel, 40 Civil Engineers & Architects, 10 Safety Practitioners, and 80 Construction Workers in Cebu City and Provinces, Philippines for evaluation. Gathered data were treated using total weighted points, weighted mean. Based on the findings and after a careful analysis and interpretation of the study, it is concluded that the efficiency of Human Resources Management in the construction industries in Cebu. It was found out that the efficiency of Human Resources Management in the construction industries in Cebu was Highly Effective in terms of effectiveness of its project planning, project leading, project organizing, project controlling, and evaluation. It is recommended that the efficiency of Human Resources Management in the construction industries in Cebu be adopted and practiced.
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Alsabbagh, Mhd Wasem, Michael A. Beazely i Leona Spasik. "Association Between Opioid-Related Mortality and History of Surgical Procedure: A Population-Based Case-Control Study". Annals of Surgery Open 5, nr 2 (5.04.2024): e412. http://dx.doi.org/10.1097/as9.0000000000000412.

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Objective: This study examined whether there is an association between opioid-related mortality and surgical procedures. Methods: A case-control study design using deceased controls compared individuals with and without opioid death and their exposure to common surgeries in the preceding 4 years. This population-based study used linked death and hospitalization databases in Canada (excluding Quebec) from January 01, 2008 to December 31, 2017. Cases of opioid death were identified and matched to 5 controls who died of other causes by age (±4 years), sex, province of death, and date of death (±1 year). Patients with HIV infection and alcohol-related deaths were excluded from the control group. Logistic regression was used to determine if there was an association between having surgery and death from an opioid-related cause by estimating the crude and adjusted odds ratios (ORs) with the corresponding 95% confidence interval (CI). Covariates included sociodemographic characteristics, comorbidities, and the number of days of hospitalization in the previous 4 years. Results: We identified 11,865 cases and matched them with 59,345 controls. About 11.2% of cases and 12.5% of controls had surgery in the 4 years before their death, corresponding to a crude OR of 0.89 (95% CI: 0.83–0.94). After adjustment, opioid mortality was associated with surgical procedure with OR of 1.26 (95% CI: 1.17–1.36). Conclusions: After adjusting for comorbidities, patients with opioid mortality were more likely to undergo surgical intervention within 4 years before their death. Clinicians should enhance screening for opioid use and risk factors when considering postoperative opioid prescribing.
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Myran, Daniel T., Peter Tanuseputro, Nathalie Auger, Lauren Konikoff, Robert Talarico i Yaron Finkelstein. "Pediatric Hospitalizations for Unintentional Cannabis Poisonings and All-Cause Poisonings Associated With Edible Cannabis Product Legalization and Sales in Canada". JAMA Health Forum 4, nr 1 (13.01.2023): e225041. http://dx.doi.org/10.1001/jamahealthforum.2022.5041.

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ImportanceCanada legalized cannabis in October 2018 but initially prohibited the sale of edibles (eg, prepackaged candies). Starting in January 2020, some provinces permitted the sale of commercial cannabis edibles. The association of legalizing cannabis edibles with unintentional pediatric poisonings is uncertain.ObjectiveTo evaluate changes in proportions of all-cause hospitalizations for poisoning due to cannabis in children during 3 legalization policy periods in Canada’s 4 most populous provinces (including 3.4 million children aged 0-9 years).Design, Setting, and ParticipantsThis repeated cross-sectional study included all hospitalizations in children aged 0 to 9 years in Ontario, Alberta, British Columbia, and Quebec between January 1, 2015, and September 30, 2021.ExposuresPrelegalization (January 2015 to September 2018); period 1, in which dried flower only was legalized in all provinces (October 2018 to December 2019); and period 2, in which edibles were legalized in 3 provinces (exposed provinces) and restricted in 1 province (control province) (January 2020 to September 2021).Main Outcomes and MeasuresThe primary outcome was the proportion of hospitalizations due to cannabis poisoning out of all-cause poisoning hospitalizations. Data analysis was performed using descriptive statistics and Poisson regression models.ResultsDuring the 7-year study period, there were 581 pediatric hospitalizations for cannabis poisoning (313 [53.9%] boys; 268 [46.1%] girls; mean [SD] age, 3.6 [2.5] years) and 4406 hospitalizations for all-cause poisonings. Of all-cause poisoning hospitalizations, the rate per 1000 due to cannabis poisoning before legalization was 57.42 in the exposed provinces and 38.50 in the control province. During period 1, the rate per 1000 poisoning hospitalizations increased to 149.71 in the exposed provinces (incidence rate ratio [IRR], 2.55; 95% CI, 1.88-3.46) and to 117.52 in the control province (IRR, 3.05; 95% CI, 1.82-5.11). During period 2, the rate per 1000 poisoning hospitalizations due to cannabis more than doubled to 318.04 in the exposed provinces (IRR, 2.16; 95% CI, 1.68-2.80) but remained similar at 137.93 in the control province (IRR, 1.18; 95% CI, 0.71-1.97).Conclusions and RelevanceThis cross-sectional study found that following cannabis legalization, provinces that permitted edible cannabis sales experienced much larger increases in hospitalizations for unintentional pediatric poisonings than the province that prohibited cannabis edibles. In provinces with legal edibles, approximately one-third of pediatric hospitalizations for poisonings were due to cannabis. These findings suggest that restricting the sale of legal commercial edibles may be key to preventing pediatric poisonings after recreational cannabis legalization.
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Martin i Schumann. "A Silicocarbonatitic Melt and Spinel-Bearing Dunite of Crustal Origin at the Parker Phlogopite Mine, Notre-Dame-du-Laus, Quebec, Canada". Minerals 9, nr 10 (6.10.2019): 613. http://dx.doi.org/10.3390/min9100613.

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The Parker phlogopite mine, located near Notre-Dame-du-Laus, Quebec, 74 km north of Ottawa, is well known among mineral collectors for its centimetric euhedral crystals of black spinel. Among the dozens of phlogopite mines active in the early 1900s in the Mont-Laurier–Bancroft corridor in the Central Metasedimentary Belt of the Grenville Province, the Parker mine is exceptional because of the association of forsterite + spinel with phlogopite. Euhedral crystals of these minerals are found “frozen” in a carbonate matrix. The carbonate dike and segregations are associated with spinel-rich dunite that contains accessory diopside, phlogopite, and pargasite, as well as ilmenite and apatite. The interstitial melt crystallized to calcite + dolomite. Hematite appeared as flakes in the melt owing to net loss of hydrogen, and the spinel underwent oxidation-induced exsolution. Our spinel crystal entrapped a domain of carbonate during growth. It also entrapped globules of boundary-layer melt that crystallized to a carbonate + sulfate + phosphate + silicate + oxide assemblage. Such globules, where present in the cumulate, are more pristine than in the coarse crystal of spinel, i.e., less affected by a hydrothermal overprint. We contend that the carbonate melt ultimately formed by the hydrous melting of marble, as supported by oxygen-isotope data on all major minerals. Melting occurred 1140 million years ago, at a time of tectonic relaxation following the Shawinigan compressive stresses.
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Romain, Ahmed Jérôme, Jacques Marleau i Aurelie Baillot. "Association between physical multimorbidity, body mass index and mental health/disorders in a representative sample of people with obesity". Journal of Epidemiology and Community Health 73, nr 9 (14.06.2019): 874–80. http://dx.doi.org/10.1136/jech-2018-211497.

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BackgroundObesity is known to be associated with poor mental health. Studies suggested that multimorbidity might explain the consequences of obesity on mental health. The objective of the present study was to examine to what extent physical multimorbidity and the severity of obesity were associated with mental health and with mental disorders.MethodsCross-sectional study including a weighted representative sample of individuals in obesity from the province of Quebec included in the 2013–2014 Canadian Community Health Survey (N=1315) and test of the replicability of the association in the three previous cycles (2011–2012, N=1180; 2009–2010, N=1166; 2007–2008, N=1298).ResultsAdjusted logistic regressions showed that when obesity classes and physical multimorbidity were considered, the latter was preferentially associated with poor perceived mental health (OR 3.58, 95% CI 2.07 to 6.22), psychological distress (OR 3.71, 95% CI 2.14 to 6.42), major depressive episode (OR 5.16, 95% CI 2.92 to 9.13), mood disorders (OR 2.31, 95% CI 1.41 to 3.78) and anxiety disorders (OR 2.46, 95% CI 1.46 to 4.16). The same associations were confirmed in the previous cycles. Obesity class was only associated with stress (OR 2.05, 95% CI 1.36 to 3.07), but this association was not confirmed in the other cycles. Both physical multimorbidity and severe obesity were associated with mental multimorbidity.ConclusionAmong people with obesity, physical multimorbidity is preferentially associated with poor mental health/disorders. There is an existence of a somatic-mental multimorbidity which should be assessed and prevented in the management of obesity.
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Sambaraju, Kishan R., Pierre DesRochers i Danny Rioux. "Factors Influencing the Regional Dynamics of Butternut Canker". Plant Disease 102, nr 4 (kwiecień 2018): 743–52. http://dx.doi.org/10.1094/pdis-08-17-1149-re.

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Butternut (Juglans cinerea) is an important component of native biodiversity in eastern North America. Of urgent concern is the survival of butternut, whose populations are declining rapidly, in large part due to an exotic pathogen, Ophiognomonia clavigignenti-juglandacearum, that causes butternut canker. The disease presently occurs throughout the range of butternut in North America, causing branch and stem cankers, dieback, and tree mortality. Despite the existential threat posed by O. clavigignenti-juglandacearum to butternut, a detailed understanding of the factors that drive cross-scale disease patterns is lacking. Therefore, we investigated the association of a range of factors, including tree attributes, topography, and weather, with butternut canker spatial dynamics at different scales using data collected in the province of Quebec, Canada. Trunk canker damage and dieback showed distinct geographic patterns. Bark phenotype was not significantly associated with trunk canker damage. Results suggest that open or dominant trees may show less dieback than intermediate or suppressed trees. Probability of the presence of trunk canker and percent dieback were proportional to the tree diameter at breast height. Temperature was positively associated with disease severity at a 1-km2 scale. Our results provide strong evidence that multiple factors, notably weather, influence butternut canker epidemiology.
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Lentz, David. "Radioelement distribution in U, Th, Mo, and rare-earth-element pegmatites, skarns, and veins in a portion of the Grenville Province, Ontario and Quebec". Canadian Journal of Earth Sciences 28, nr 1 (1.01.1991): 1–12. http://dx.doi.org/10.1139/e91-001.

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Gamma-ray spectrometer measurements were obtained at and in the vicinity of 104 of the 124 U, Th, Mo, and rare-earth-element (REE) occurrences examined in the Central Metasedimentary Belt of the Grenville Province. Spatial, temporal, mineralogical, and geochemical relationships among granitic pegmatites, phlogopite – scapolite – Ca pyroxene skarns, and fluorite – apatite – calcite veins hosting U, Th, Mo, and REE minerals indicate a common magmatic–hydrothermal origin. Quartz–feldspar gneisses in the Central Metasedimentary Belt (n = 54) have low abundances of uranium (1–7 ppm) and thorium (4–27 ppm) suggesting that partial melting, fractional crystallization, and volatile phase separation were responsible for the enrichment of uranium (2–37 ppm) and thorium (5–102 ppm) in uncontaminated granitic pegmatites (n = 163) derived during ultrametamorphism. The U/Th ratio is probably inherited from the source quartz–feldspar gneiss protolith and enhanced during fractionation.Average U and Th concentrations and U/Th ratios at numerous localities show significant positive correlations among pegmatites, skarns, and veins, providing further evidence for a related origin. The interaction of the pegmatite-derived hydrothermal fluids with host rocks produced a spectrum of types and styles of alteration, which include (i) hybridization and (or) endoskarnification along pegmatite margins; (ii) marble- and clinopyroxenite-hosted exoskarn; and (iii) fluorite–apatite–calcite veins. The deposition of U, Th, Mo, and REE from the evolving hydrothermal fluid is responsible for the heterogeneous distribution of U, Th, and REE minerals and molybdenite within pegmatites, skarns, and veins at each locality. Secondary enrichment of uranium in association with hematitized sheared pegmatites and veins may be responsible for the observed large variation in U/Th ratios at some sites.
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Kaboré, Jean-Luc, M. Gabrielle Pagé, Lise Dassieu, Éric Tremblay, Mike Benigeri, Denis A. Roy, Anaïs Lacasse i Manon Choinière. "Doctor shopping among chronic noncancer pain patients treated with opioids in the province of Quebec (Canada): incidence, risk factors, and association with the occurrence of opioid overdoses". PAIN Reports 6, nr 3 (wrzesień 2021): e955. http://dx.doi.org/10.1097/pr9.0000000000000955.

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Stan, Simona, Emile Levy, Edgard E. Delvin, James A. Hanley, Benoît Lamarche, Jennifer O’Loughlin, Gilles Paradis i Marie Lambert. "Distribution of LDL Particle Size in a Population-Based Sample of Children and Adolescents and Relationship with Other Cardiovascular Risk Factors". Clinical Chemistry 51, nr 7 (1.07.2005): 1192–200. http://dx.doi.org/10.1373/clinchem.2004.046771.

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Abstract Background: Smaller, denser LDL particles are associated with an increased risk for cardiovascular diseases (CVD). In youths, data on the distribution of LDL particle size and on its association with other CVD risk factors are limited. Methods: We determined LDL peak particle size by nondenaturing 2%–16% gradient gel electrophoresis in a representative sample of 2249 youths 9, 13, and 16 years of age who participated in a school-based survey conducted in 1999 in the province of Quebec, Canada. Standardized clinical measurements and fasting plasma lipid, glucose, and insulin concentrations were available. Results: The LDL peak particle size distribution was gaussian. The 5th, 50th (median), and 95th percentiles by age and sex were 255.5–258.6, 262.1–263.2, and 268.1–269.5 Å, respectively. The prevalence of the small, dense LDL phenotype (LDL peak particle size ≤255 Å) was 10% in participants with insulin resistance syndrome (IRS), in contrast to 1% in those without IRS. In a multiple regression analysis, the association of LDL size with other CVD risk factors [apolipoprotein B, HDL-cholesterol (HDL-C), triglyceride (TG), and insulin concentrations, and body mass index] was strongest with TG and HDL-C concentrations: a 1 SD increase in loge-transformed TG concentration was associated with a 1.2 Å reduction in LDL size, and a 1 SD increase in HDL-C was associated with a 1.1 Å increase in LDL size. Conclusions: Although the small, dense LDL phenotype is less prevalent in youths than adults, its prevalence is clearly increased in childhood IRS. Metabolic correlates of LDL size are similar in youths and adults.
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Lambert, Marie, Edgard E. Delvin, Gilles Paradis, Jennifer O’Loughlin, James A. Hanley i Emile Levy. "C-Reactive Protein and Features of the Metabolic Syndrome in a Population-Based Sample of Children and Adolescents". Clinical Chemistry 50, nr 10 (1.10.2004): 1762–68. http://dx.doi.org/10.1373/clinchem.2004.036418.

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Abstract Background: C-Reactive protein (CRP) is a risk marker for type 2 diabetes and cardiovascular diseases. In youth, limited data are available on the distribution of high-sensitivity CRP as well as on its association with components of the metabolic syndrome. Methods: In 1999, we conducted a school-based survey of a representative sample of youths 9, 13, and 16 years of age in the province of Quebec, Canada. Standardized clinical measurements and fasting plasma lipid, glucose, insulin, and CRP concentrations were available for 2224 individuals. Results: The distribution of CRP was positively skewed. The median and 95th percentile values by age and sex ranged from &lt;0.2 to 0.56 mg/L and from 2.72 to 6.28 mg/L, respectively. A total of 7.7% of 9-year-olds, 5.5% of 13-year-olds, and 12.8% of 16-year-olds had CRP concentrations &gt;3.0 mg/L, the threshold defining the adult high-risk category. We observed a strong relationship between CRP concentrations and both body mass index (BMI) and fasting insulin values. The association between CRP and insulin concentration was markedly attenuated after adjustment for BMI, whereas that between CRP and BMI remained unchanged after adjustment for insulin: a 1 SD increase in BMI was associated with a 52% increase in CRP concentration. An increased CRP concentration was independently associated with a worsening of the lipid profile, whereas the association between increased CRP values and high systolic blood pressure was no longer statistically significant after adjustment for BMI. Conclusions: The metabolic correlates of excess weight, including a state of low-grade systemic inflammation, are detectable early in life. Their health impact in adults remains to be fully examined.
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Pitrou, Isabelle, Djamal Berbiche i Helen-Maria Vasiliadis. "Mental health and satisfaction with primary care services in older adults: a study from the patient perspective on four dimensions of care". Family Practice 37, nr 4 (23.03.2020): 459–64. http://dx.doi.org/10.1093/fampra/cmaa019.

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Abstract Background Few studies have examined the association between mental health and satisfaction with primary care services in community-dwelling older adults. Objective To examine the association between mental health in older adults and low satisfaction with primary care services within four dimensions of care. Methods This secondary data analysis included 1624 older adults participating in the ‘Étude sur la Santé des Aînés Services’ (ESA-Services study) and recruited in primary care practices between 2011 and 2013 in the province of Quebec. Patient satisfaction and experience with care were assessed during face-to-face interviews with questions adapted from the Primary Care Assessment Survey. Self-reported mental health indicators included depression, anxiety, suicidal ideation, psychological distress and cognition. We conducted four logistic regressions to examine the associations between mental health and low satisfaction in the following dimensions of care: continuity of care, provider–patient interactions, adequacy of care and physical environment. Results Nearly half of participants (48.5%) reported low satisfaction in at least one dimension of care examined. High psychological distress was associated with low satisfaction with provider–patient interactions [odds ratio (OR) = 1.02; 95% confidence interval (CI) = 1.00–1.04] and adequacy of care (OR = 1.04; 95% CI = 1.01–1.06). The presence of an anxiety disorder was associated with low satisfaction in adequacy of care (OR = 1.64; 95% CI = 1.00–2.72). Worse cognitive functioning was associated with low satisfaction in continuity of care, provider–patient interaction and adequacy of care. Conclusions Mental health was consistently associated with low satisfaction within dimensions of care. Results support the need for increased attention when delivering care to older adults with mental health problems.
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Gamache, Pierre-Luc, Ikhlass Haj Salem, Noémie Roux-Dubois, Jacques Le Bouthillier, Ziv Gan-Or i Nicolas Dupré. "Exposure to Pesticides and Welding Hastens the Age-at-Onset of Parkinson’s Disease". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 46, nr 6 (25.07.2019): 711–16. http://dx.doi.org/10.1017/cjn.2019.248.

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ABSTRACT:Background:The age-at-onset (AAO) of Parkinson’s disease (PD) is thought to be influenced by environmental factors and polygenic predispositions. Professional exposures to pesticides and toxic metals were shown to be associated with an earlier onset in small sample studies.Aim of Study:The aim of this study was to confirm the association between professional exposures to pesticides and toxic metals and the AAO of PD, on a larger cohort of patients, defined with a clinic-based ascertainment scheme.Methods:We used an incident cohort of 290 patients recruited through three designated movement disorder clinics in the province of Quebec, Canada. Patients completed a detailed questionnaire regarding professional exposures to pesticides and toxic metals. We compared the AAO in patients without prior professional exposure (N = 170) and those with exposure to pesticides (N = 53) or toxic metals through welding (N = 30). We further subdivided patients exposed to pesticides according to the frequency and proximity of their contacts.Results:Patients with prior exposure to pesticides (AAO = 54.74 years) or toxic metals (54.27 years) had a significantly earlier AAO compared to the control group (59.26 years) (p = 0.003). In those exposed to pesticides, closer (p = 0.03) and more frequent (p = 0.02) contacts were negatively correlated with AAO.Conclusion:Exposure to pesticides and toxic metals were both associated with an earlier onset of PD, an effect that was greater with higher levels of exposure, both in terms of frequency and proximity.
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Sirois, Caroline, Véronique Boiteau, Yohann Chiu, Rodica Gilca i Marc Simard. "Exploring the associations between polypharmacy and COVID-19-related hospitalisations and deaths: a population-based cohort study among older adults in Quebec, Canada". BMJ Open 12, nr 3 (marzec 2022): e060295. http://dx.doi.org/10.1136/bmjopen-2021-060295.

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ObjectivesTo study the association between polypharmacy and the risk of hospitalisation and death in cases of COVID-19 in the population over the age of 65.DesignPopulation-based cohort study.SettingQuebec Integrated Chronic Disease Surveillance System, composed of five medico-administrative databases, in the province of Quebec, Canada.Participants32 476 COVID-19 cases aged over 65 whose diagnosis was made between 23 February 2020 and 15 March 2021, and who were covered by the public drug insurance plan (thus excluding those living in long-term care). We counted the number of different medications they claimed between 1 April 2019 and 31 March 2020.Outcome measuresRobust Poisson regression was used to calculate relative risk of hospitalisation and death associated with the use of multiple medications, adjusting for age, sex, chronic conditions, material and social deprivation and living environment.ResultsOf the 32 476 COVID-19 cases included, 10 350 (32%) were hospitalised and 4146 (13%) died. Compared with 0–4 medications, polypharmacy exposure was associated with increased hospitalisations, with relative risks ranging from 1.11 (95% CI 1.04 to 1.19) for those using 5–9 medications to 1.62 (95% CI 1.51 to 1.75) for those using 20+. Similarly, the risk of death increased with the number of medications, from 1.13 (95% CI 0.99 to 1.30) for those using (5–9 medications to 1.97 (95% CI 1.70 to 2.27) (20+). Increased risk was mainly observed in younger groups.ConclusionsPolypharmacy was significantly associated with the risk of hospitalisations and deaths related to COVID-19 in this cohort of older adults. Polypharmacy may represent a marker of vulnerability, especially for younger groups of older adults.
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Boudreault, Catherine, Pierre Drapeau, Mathieu Bouchard, Martin-Hugues St-Laurent, Louis Imbeau i Yves Bergeron. "Contrasting responses of epiphytic and terricolous lichens to variations in forest characteristics in northern boreal ecosystems". Canadian Journal of Forest Research 45, nr 5 (maj 2015): 595–606. http://dx.doi.org/10.1139/cjfr-2013-0529.

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The main environmental factors that drive lichen communities are still poorly known in northern boreal ecosystems. This study compares the effects of forest stand characteristics (height, canopy cover, and age) on fruticose epiphytic and terricolous lichen communities across a large region located at the interface between closed-crown boreal forests and northern open woodlands in the province of Quebec (Canada). The dataset consists of 875 plots spread across a 242 000 km2 territory that ranges from the eastern to the western extremities of the province. The biomass of fruticose epiphytic lichens (Alectoria, Bryoria, Evernia, and Usnea) was evaluated at the branch, tree, and plot levels, and terricolous lichen cover (Cladonia spp.) was evaluated at the plot level. The results indicate that epiphytic and terricolous lichens respond significantly but differently to variations in forest characteristics. At the plot level, epiphytic lichen biomass was highest in the oldest stands (>100 years) and lowest in stand with low canopy cover (<25%) or in stands dominated by relatively short trees (<7 m). By contrast, terricolous lichen cover was highest in stands dominated by short (<7 m) or mid-sized (7–12 m) trees and lowest in stands with a relatively high canopy cover (>40%) or stands of intermediate age (60 to 100 years old). Species composition of epiphytic communities was also examined, and some species or genera exhibit a strong association with older stands (Alectoria sarmentosa (Ach.) Ach., Bryoria spp.) or with specific regions along the ca. 1500 km east–west gradient (Evernia mesomorpha Nyl. in the western part, Bryoria spp. in the central part, and A. sarmentosa in the eastern part). In terms of conservation, these results indicate that epiphytic lichens communities are potentially sensitive to the preferential logging of older stands. Both epiphytic and terricolous lichen communities are also potentially sensitive to expected climate change effects such as increased fire frequencies or increased forest growth.
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Gotfrit, Joanna, Ashley Jackson, John J. W. Shin, David J. Stewart, Ranjeeta Mallick i Paul Wheatley-Price. "Determinants of the Cancer Drug Funding Process in Canada". Current Oncology 29, nr 3 (15.03.2022): 1997–2007. http://dx.doi.org/10.3390/curroncol29030162.

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Background: Canada has a publicly funded healthcare system with a complex drug funding process. After Health Canada approval to market a drug, the pan-Canadian Oncology Drug Review (pCODR) (now renamed the CADTH reimbursement review) makes a non-binding funding recommendation to the Canadian provinces (except Quebec), which each then decide whether the drug will be publicly funded. We identified the determinants of funding in this process. Methods: We analyzed drugs for advanced lung (n = 15), breast (n = 8), colorectal (CRC) (n = 7), melanoma (n = 10), and neuroendocrine (NET) (n = 3) cancers undergoing the funding decision process from 2011 to 2019. Determinants of funding assessed in the model included list price, cancer type, drug class, and pCODR recommendation. The primary outcome was the correlation between list price and time to funding (TTF: Health Canada approval to first provincial funding). Secondary outcomes included an exploratory analysis of predictors of drug funding. Results: We analyzed 43 drugs: targeted agents 72%, immunotherapy 20%, chemotherapy 7%. A total of 72% were funded in at least one province. Median TTF was 379 days (IQR 203–601). Median list price (28-day course) was CAD 8213 (IQR CAD 5391–9445). Higher list price was not correlated with TTF (correlation coefficient −0.20, p = 0.28). There was no association between list price and pCODR recommendation or the decision to fund in at least one province. A positive pCODR recommendation correlated with the provinces’ funding decisions (p < 0.001), where 89% of drugs with a positive recommendation were funded and 100% of drugs with a negative recommendation were not funded. Tumor type was predictive of TTF (p < 0.001): CRC drugs were the slowest at a median of 2541 days (IQR 702–4379), and NETs were the quickest at a median of 0 days (IQR 0–502). Cancer type predicted decision to fund in at least one province (p = 0.005), with funding for 100% of NET drugs at the high end and 29% of CRC drugs at the low end. Drug class was predictive of TTF (p = 0.01): 465 days (IQR 245–702) for targeted agents, 443 days (IQR 298–587) for chemotherapy, and 339 days (IQR 164–446) for immunotherapy. Conclusions: Determinants of drug funding included cancer type, drug class, and pCODR recommendation but not list price. Factors other than cost were more heavily weighted in the funding decisions of cancer drugs in Canadian provinces.
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Li, Muzi, Kieran J. O'Donnell, Jean Caron, Carl D'Arcy i Xiangfei Meng. "Impact of parental socioeconomic status on offspring’s mental health: protocol for a longitudinal community-based study". BMJ Open 11, nr 2 (luty 2021): e038409. http://dx.doi.org/10.1136/bmjopen-2020-038409.

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IntroductionSocioeconomic status (SES) affects physical and mental health and cognitive functioning. The association between SES changes (SES mobility) and health has ethical and political implications in that the pernicious effects of inequality and the differential impact on social classes of economic and social policies. There is a lack of research conducted to explore the intergenerational transmission of parental SES changes on the offspring’s mental health and cognitive functioning. We aim to fill this gap and identify roles of parental SES changes in offspring’s mental health and cognitive outcomes.Methods and analysisThis study will be based on a longitudinal cohort from the most populous municipality in the Canadian province of Quebec. Participants and their biological offspring will be invited to this study. For those with informed consent, we will collect their information on mental health, psychiatric disorders, cognitive functioning and early life experiences for offspring. Latent class growth analysis will be used to identify parental SES mobility groups. Multivariate regression analyses will be used to explore the roles of early life stress, parental SES mobility and their interactions in psychiatric disorders and cognitive functioning. Subgroup analyses (males and females) are also planned.Ethics and disseminationThis study has been given ethical approval by the Research Ethics Board of the Douglas Mental Health University Institute (IUSMD-18/17). Each participant will provide informed consent on participation. We will disseminate research findings through publication in peer-reviewed academic journals and presentations at conferences. Lay summaries of major research findings will also be shared annually with our partners in the health system and community agencies located in the catchment area.
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Garneau, A. P., A. A. Marcoux, R. Frenette-Cotton, F. Mac-Way, J. L. Lavoie i P. Isenring. "Molecular insights into the normal operation, regulation, and multisystemic roles of K+-Cl− cotransporter 3 (KCC3)". American Journal of Physiology-Cell Physiology 313, nr 5 (1.11.2017): C516—C532. http://dx.doi.org/10.1152/ajpcell.00106.2017.

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Long before the molecular identity of the Na+-dependent K+-Cl− cotransporters was uncovered in the mid-nineties, a Na+-independent K+-Cl− cotransport system was also known to exist. It was initially observed in sheep and goat red blood cells where it was shown to be ouabain-insensitive and to increase in the presence of N-ethylmaleimide (NEM). After it was established between the early and mid-nineties, the expressed sequence tag (EST) databank was found to include a sequence that was highly homologous to those of the Na+-dependent K+-Cl− cotransporters. This sequence was eventually found to code for the Na+-independent K+-Cl− cotransport function that was described in red blood cells several years before. It was termed KCC1 and led to the discovery of three isoforms called KCC2, KCC3, and KCC4. Since then, it has become obvious that each one of these isoforms exhibits unique patterns of distribution and fulfills distinct physiological roles. Among them, KCC3 has been the subject of great attention in view of its important role in the nervous system and its association with a rare hereditary sensorimotor neuropathy (called Andermann syndrome) that affects many individuals in Quebec province (Canada). It was also found to play important roles in the cardiovascular system, the organ of Corti, and circulating blood cells. As will be seen in this review, however, there are still a number of uncertainties regarding the transport properties, structural organization, and regulation of KCC3. The same is true regarding the mechanisms by which KCC3 accomplishes its numerous functions in animal cells.
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Gelfond, Anna L. "The Concept of Potential Spatial Frameworks of Historical Settlements". Scientific journal “ACADEMIA. ARCHITECTURE AND CONSTRUCTION”, nr 1 (18.03.2019): 26–34. http://dx.doi.org/10.22337/2077-9038-2019-1-26-34.

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The topic of the article arose on the basis of the current promises of recent times, which largely determine the creative tasks of both practicing architects and scientists in the field of theory and history of architecture: the implementation of the priority project "The formation of a comfortable urban environment", the all-Russian contest "Historical settlements and small towns", the formation in the Russian Federation of a newlist of historical settlements, which is being worked on by the Association "Russian province" scientific and expert Council. The article introduces the concept of "potential spatial framework of historical settlement", which is formed as an integral one on the basis of natural-ecological, historical- cultural, social and business spatial frameworks of the city. Depending on the "dominant" dictating a particular type of potential spatial framework, it can be museum and exhibition, cultural and educational, pilgrimage, tourist, ethnographic, etc. Frameworks nodes fix respectively valuable natural landscapes, objects of cultural heritage, elements of the system of service. Axes - transport and pedestrian communications carried out at different hierarchical levels: connection of cultural heritage objects in a historical settlement; connection of transit public spaces; communication within districts; connection of historical settlements with each other; their connection with a large city. Public space is considered as a typological unit of the architectural environment; which merged its natural, historical and social components. In the creation of potential spatial frameworks in small historical cities and historical centers oflarge cities, where the basis of spatial development are monuments of architecture and it is possible to implement the principle of continuity of the public spaces, the approach to the revitalization of historical settlements is seen.
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Ramos, Élodie, Martin St-André, Évelyne Rey, Driss Oraichi i Anick Bérard. "Duration of antidepressant use during pregnancy and risk of major congenital malformations". British Journal of Psychiatry 192, nr 5 (maj 2008): 344–50. http://dx.doi.org/10.1192/bjp.bp.107.042523.

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BackgroundAntidepressant use during the gestational period is a controversial topic.AimsTo determine whether duration of antidepressant use during the first trimester increases the risk of major congenital malformations in offspring of women diagnosed with psychiatric disorders.MethodA case-control study was performed among women who had been pregnant between January 1998 and December 2002. Data were obtained from a Medication and Pregnancy registry, built by linking three databases from the province of Quebec, and a self-administered questionnaire. Women eligible for this study had to be 15–45 years old at the beginning of pregnancy, have at least one diagnosis of psychiatric disorder before pregnancy, have used antidepressants for ≥ 30 days in the year prior to pregnancy and have a pregnancy ending with a delivery. Cases were defined as any major congenital malformation diagnosed in the offspring's first year of life. Odds ratios, adjusted for relevant confounders, were estimated using logistic regression.ResultsAmong the 2329 women meeting the inclusion criteria, 189 (8.1%) infants were born with a major congenital malformation. Duration of antidepressant use during the first trimester of pregnancy was not associated with an increased risk of major congenital malformations: 1–30 days v. 0 day, adjusted OR=1.23 (95% CI 0.77–1.98); 31–60 days v. 0 day, adjusted OR=1.03 (95% CI 0.63–1.69); ≥ 61 days v. 0 day, adjusted OR=0.92 (95% CI 0.50–1.69).ConclusionsThese data do not support an association between duration of antidepressant use during the first trimester of pregnancy and major congenital malformations in the offspring of women with psychiatric disorders. These findings should help clinicians decide whether to continue antidepressant therapy during pregnancy.
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Farhat, Imen, Lynne Moore, Teegwendé Valérie Porgo, Marie-Pier Patton, Pier-Alexandre Tardif, Catherine Truchon, Simon Berthelot i in. "Resource use for older people hospitalised due to injury in a Canadian integrated trauma system: a retrospective multicenter cohort study". Age and Ageing 48, nr 6 (22.08.2019): 867–74. http://dx.doi.org/10.1093/ageing/afz097.

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Abstract Background Injuries represent one of the leading causes of preventable morbidity and mortality. For countries with ageing populations, admissions of injured older patients are increasing exponentially. Yet, we know little about hospital resource use for injured older patients. Our primary objective was to evaluate inter-hospital variation in the risk-adjusted resource use for injured older patients. Secondary objectives were to identify the determinants of resource use and evaluate its association with clinical outcomes. Methods We conducted a multicenter retrospective cohort study of injured older patients (≥65 years) admitted to any trauma centres in the province of Quebec (2013–2016, N = 33,184). Resource use was estimated using activity-based costing and modelled with multilevel linear models. We conducted separate subgroup analyses for patients with trauma and fragility fractures. Results Risk-adjusted resource use varied significantly across trauma centres, more for older patients with fragility fractures (intra-class correlation coefficients [ICC] = 0.093, 95% CI [0.079, 0.102]) than with trauma (ICC = 0.047, 95% CI = 0.035–0.051). Risk-adjusted resource use increased with age, and the number of comorbidities, and varied with discharge destination (P < 0.001). Higher hospital resource use was associated with higher incidence of complications for trauma (Pearson correlation coefficient [r] = 0.5, 95% CI = 0.3–0.7) and fragility fractures (r = 0.5, 95% CI = 0.3–0.7) and with higher mortality for fragility fractures (r = 0.4, 95% CI = 0.2–0.6). Conclusions We observed significant inter-hospital variations in resource use for injured older patients. Hospitals with higher resource use did not have better clinical outcomes. Hospital resource use may not always positively impact patient care and outcomes. Future studies should evaluate mechanisms, by which hospital resource use impacts care.
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Liu, S., J. Rouleau, JA León, R. Sauve, KS Joseph i JG Ray. "Impact of pre-pregnancy diabetes mellitus on congenital anomalies, Canada, 2002–2012". Health Promotion and Chronic Disease Prevention in Canada 35, nr 5 (lipiec 2015): 79–84. http://dx.doi.org/10.24095/hpcdp.35.5.01.

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Objective To examine the impact of pre-pregnancy diabetes mellitus (DM) on the population birth prevalence of congenital anomalies in Canada. Methods We carried out a population-based study of all women who delivered in Canadian hospitals (except those in the province of Quebec) between April 2002 and March 2013 and their live-born infants with a birth weight of 500 grams or more and/or a gestational age of 22 weeks or more. Pre-pregnancy type 1 or type 2 DM was identified using ICD-10 diagnostic codes. The association between DM and all congenital anomalies as well as specific congenital anomaly categories was estimated using adjusted odds ratios; the impact was calculated as a population attributable risk percent (PAR%). Results There were 118 892 infants with a congenital anomaly among 2 839 680 live births (41.9 per 1000). While the prevalence of any congenital anomaly declined from 50.7 per 1000 live births in 2002/03 to 41.5 per 1000 in 2012/13, the corresponding PAR% for a congenital anomaly related to pre-pregnancy DM rose from 0.6% (95% confidence interval [CI]: 0.4–0.8) to 1.2% (95% CI: 0.9–1.4). Specifically, the PAR% for congenital cardiovascular defects increased from 2.3% (95% CI: 1.7–2.9) to 4.2% (95% CI: 3.5–4.9) and for gastrointestinal defects from 0.8% (95% CI: 0.2–1.9) to 1.4% (95% CI: 0.7–2.6) over the study period. Conclusion Although there has been a relative decline in the prevalence of congenital anomalies in Canada, the proportion of congenital anomalies due to maternal prepregnancy DM has increased. Enhancement of preconception care initiatives for women with DM is recommended.
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Magier, Megan, Karen A. Patte, Katelyn Battista, Adam G. Cole i Scott T. Leatherdale. "Are School Substance Use Policy Violation Disciplinary Consequences Associated with Student Engagement in Cannabis?" International Journal of Environmental Research and Public Health 17, nr 15 (31.07.2020): 5549. http://dx.doi.org/10.3390/ijerph17155549.

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Schools are increasingly concerned about student cannabis use with the recent legalization in Canada; however, little is known about how to effectively intervene when students violate school substance use policies. The purpose of this study is to assess the disciplinary approaches present in secondary schools prior to cannabis legalization and examine associations with youth cannabis use. This study used Year 6 (2017/2018) data from the COMPASS (Cannabis use, Obesity, Mental Health, Physical Activity, Alcohol use, Smoking, Sedentary behavior) study including 66,434 students in grades 9 through 12 and the 122 secondary schools they attend in British Columbia, Alberta, Ontario, and Quebec. Student questionnaires assessed youth cannabis use and school administrator surveys assessed potential use of 14 cannabis use policy violation disciplinary consequences through a (“check all that apply”) question. Regression models tested the association between school disciplinary approaches and student cannabis use with student- (grade, sex, ethnicity, tobacco use, binge drinking) and school-level covariates (province, school area household median income). For first-offence violations of school cannabis policies, the vast majority of schools selected confiscating the product (93%), informing parents (93%), alerting police (80%), and suspending students from school (85%), among their disciplinary response options. Few schools indicated requiring students to help around the school (5%), issuing a fine (7%), or assigning additional class work (8%) as potential consequences. The mean number of total first-offence consequences selected by schools was 7.23 (SD = 2.14). Overall, 92% of schools reported always using a progressive disciplinary approach in which sanctions get stronger with subsequent violations. Students were less likely to report current cannabis use if they attended schools that indicated assigning additional class work (OR 0.57, 95% CI (0.38, 0.84)) or alerting the police (OR 0.81, 95% CI (0.67, 0.98)) among their potential first-offence consequences, or reported always using the progressive discipline approach (OR 0.77, 95% CI (0.62, 0.96)) for subsequent cannabis policy violations. In conclusion, results reveal the school disciplinary context in regard to cannabis policy violations in the year immediately preceding legalization. Various consequences for cannabis policy violations were being used by schools, yet negligible association resulted between the type of first-offence consequences included in a school’s range of disciplinary approaches and student cannabis use.
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Palayew, Adam, Alexandra M. Schmidt, Sahar Saeed, Curtis L. Cooper, Alexander Wong, Valérie Martel-Laferrière, Sharon Walmsley, Joseph Cox i Marina B. Klein. "Estimating an individual-level deprivation index for HIV/HCV coinfected persons in Canada". PLOS ONE 16, nr 4 (19.04.2021): e0249836. http://dx.doi.org/10.1371/journal.pone.0249836.

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Background HIV-HCV coinfected individuals are often more deprived than the general population. However, deprivation is difficult to measure, often relying on aggregate data which does not capture individual heterogeneity. We developed an individual-level deprivation index for HIV-HCV co-infected persons that encapsulated social, material, and lifestyle factors. Methods We estimated an individual-level deprivation index with data from the Canadian Coinfection Cohort, a national prospective cohort study. We used a predetermined process to select 9 out of 19 dichotomous variables at baseline visit to include in the deprivation model: income >$1500/month; education >high school; employment; identifying as gay or bisexual; Indigenous status; injection drug use in last 6 months; injection drug use ever; past incarceration, and past psychiatric hospitalization. We fitted an item response theory model with: severity parameters (how likely an item was reported), discriminatory parameters, (how well a variable distinguished index levels), and an individual parameter (the index). We considered two models: a simple one with no provincial variation and a hierarchical model by province. The Widely Applicable Information Criterion (WAIC) was used to compare the fitted models. To showcase a potential utility of the proposed index, we evaluated with logistic regression the association of the index with non-attendance to a second clinic visit (as a proxy for disengagement) and using WAIC compared it to a model containing all the individual parameters that compose the index as covariates. Results We analyzed 1547 complete cases of 1842 enrolled participants. According to the WAIC the hierarchical model provided a better fit when compared to the model that does not consider the individual’s province. Values of the index were similarly distributed across the provinces. Overall, past incarceration, education, and unemployment had the highest discriminatory parameters. However, in each province different components of the index were associated with being deprived reflecting local epidemiology. For example, Saskatchewan had the highest severity parameter for Indigenous status while Quebec the lowest. For the secondary analysis, 457 (30%) failed to attend a second visit. A one-unit increase in the index was associated with 17% increased odds (95% credible interval, 2% to 34%) of not attending a second visit. The model with just the index performed better than the model with all the components as covariates in terms of WAIC. Conclusion We estimated an individual-level deprivation index in the Canadian Coinfection cohort. The index identified deprivation profiles across different provinces. This index and the methodology used may be useful in studying health and treatment outcomes that are influenced by social disparities in co-infected Canadians. The methodological approach described can be used in other studies with similar characteristics.
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Pongou, Roland, Bright Opoku Ahinkorah, Marie Christelle Mabeu, Arunika Agarwal, Stéphanie Maltais, Aissata Boubacar Moumouni i Sanni Yaya. "Identity and COVID-19 in Canada: Gender, ethnicity, and minority status". PLOS Global Public Health 3, nr 5 (24.05.2023): e0001156. http://dx.doi.org/10.1371/journal.pgph.0001156.

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Background During the COVID-19 pandemic, growing evidence from the United States, the United Kingdom, and China has demonstrated the unequal social and economic burden of this health crisis. Yet, in Canada, studies assessing the socioeconomic and demographic determinants of COVID-19, and how these determinants vary by gender and ethnic minority status, remain scarce. As new strains of COVID-19 emerge, it is important to understand the disparities to be able to initiate policies and interventions that target and prioritise the most at-risk sub-populations. Aim The objective of this study is to assess the socioeconomic and demographic factors associated with COVID-19-related symptoms in Canada, and how these determinants vary by identity factors including gender and visible minority status. Methods We implemented an online survey and collected a nationally representative sample of 2,829 individual responses. The original data collected via the SurveyMonkey platform were analysed using a cross-sectional study. The outcome variables were COVID-19-related symptoms among respondents and their household members. The exposure variables were socioeconomic and demographic factors including gender and ethnicity as well as age, province, minority status, level of education, total annual income in 2019, and number of household members. Descriptive statistics, chi-square tests, and multivariable logistic regression analyses were performed to test the associations. The results were presented as adjusted odds ratios (aORs) at p < 0.05 and a 95% confidence interval. Results We found that the odds of having COVID-19-related symptoms were higher among respondents who belong to mixed race [aOR = 2.77; CI = 1.18–6.48] and among those who lived in provinces other than Ontario and Quebec [aOR = 1.88; CI = 1.08–3.28]. There were no significant differences in COVID-19 symptoms between males and females, however, we did find a significant association between the province, ethnicity, and reported COVID-19 symptoms for female respondents but not for males. The likelihood of having COVID-19-related symptoms was also lower among respondents whose total income was $100,000 or more in 2019 [aOR = 0.18; CI = 0.07–0.45], and among those aged 45–64 [aOR = 0.63; CI = 0.41–0.98] and 65–84 [aOR = 0.42; CI = 0.28–0.64]. These latter associations were stronger among non-visible minorities. Among visible minorities, being black or of the mixed race and living in Alberta were associated with higher odds of COVID-19-related symptoms. Conclusion We conclude that ethnicity, age, total income in 2019, and province were significantly associated with experiencing COVID-19 symptoms in Canada. The significance of these determinants varied by gender and minority status. Considering our findings, it will be prudent to have COVID-19 mitigation strategies including screening, testing, and other prevention policies targeted toward the vulnerable populations. These strategies should also be designed to be specific to each gender category and ethnic group, and to account for minority status.
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Garuti, Giorgio, i Federica Zaccarini. "Naldrettite (Pd2Sb): A new find in Brazil and comparison with worldwide occurrences". Canadian Mineralogist 59, nr 6 (1.11.2021): 1801–20. http://dx.doi.org/10.3749/canmin.2000121.

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ABSTRACT Naldrettite (Pd2Sb) is a PGM discovered in 2005 in Mesamax Northwest deposit, Ungava region, Quebec, Canada. Before and after its approval, PGM with the naldrettite type composition have been reported from a number of localities worldwide. Most frequently, naldrettite has been documented in magmatic Ni–Cu–PGE sulfide deposits, hydrothermal veins in porphyry coppers of the Cu–Au type, and PGE deposits of Alaskan-type zoned intrusions. Naldrettite has been occasionally found in metasomatic Sb–As sulfide ore, metamorphic Ni–oxide ore, and podiform chromitites, although these occurrences have not been fully constrained by solid chemical analyses or paragenetic reconstruction. In this paper we report the first discovery of naldrettite in Brazil. This new finding occurs in a chromitite sample collected in the Luanga Complex, a Neo-archaean layered intrusion in the Carajás Mineral Province. Paragenetic association with alteration assemblages (ferrianchromite, Fe-hydroxides, chlorite) suggests precipitation of naldrettite from metamorphic hydrothermal fluids. The average composition of the Luanga sample (Pd1.76Pt0.24)Σ2.00(Sb0.57As0.43)Σ1.00 shows major substitution of Pt and As. These elements were derived from the breakdown of primary sperrylite, and were incorporated in naldrettite deposited by percolating fluids, at temperature below 350 °C (maximum temperature registered by the crystallization of associated chlorite). An overview of documented occurrences indicates that naldrettite can form in a variety of igneous rocks (ultramafic, mafic, felsic), even involving minimal concentrations of Pd and Sb. Crystallization of naldrettite generally occurs in the post-magmatic stage due to the activity of hydrothermal fluids containing volatile species Sb, As, Bi, Te, and Pd due to its higher mobility compared with the other PGE. A major issue concerns the origin of fluids that can be: (1) “residual”, after the main crystallization of the host magma, (2) “metamorphic”, during regional metamorphism or serpentinization, and (3) “metasomatic”, emanating from an exotic magma intrusion. The combination of two or three of these factors is the most likely process observed in the naldrettite-bearing complexes.
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Lacasse, Anaïs, Patricia Bourgault, Yannick Tousignant-Laflamme, Roxanne Courtemanche-Harel i Manon Choinière. "Development and Validation of the French-Canadian Chronic Pain Self-Efficacy Scale". Pain Research and Management 20, nr 2 (2015): 75–83. http://dx.doi.org/10.1155/2015/832875.

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BACKGROUND: Perceived self-efficacy is a non-negligible outcome when measuring the impact of self-management interventions for chronic pain patients. However, no validated, chronic pain-specific self-efficacy scales exist for studies conducted with French-speaking populations.OBJECTIVES: To establish the validity of the use of the French-Canadian Chronic Pain Self-efficacy Scale (FC-CPSES) among chronic pain patients.METHODS: The Chronic Disease Self-Efficacy Scale is a validated 33-item self-administered questionnaire that measures perceived self-efficacy to perform self-management behaviours, manage chronic disease in general and achieve outcomes (a six-item version is also available). This scale was adapted to the context of chronic pain patients following cross-cultural adaptation guidelines. The FC-CPSES was administered to 109 fibromyalgia and 34 chronic low back pain patients (n=143) who participated in an evidence-based self-management intervention (the PASSAGE program) offered in 10 health care centres across the province of Quebec. Cronbach’s alpha coefficients (α) were calculated to determine the internal consistency of the 33- and six-item versions of the FC-CPSES. With regard to convergent construct validity, the association between the FC-CPSES baseline scores and related clinical outcomes was examined. With regard to the scale’s sensitivity to change, pre- and postintervention FC-CPSES scores were compared.RESULTS: Internal consistency was high for both versions of the FC-CPSES (α=0.86 to α=0.96). Higher self-efficacy was significantly associated with higher mental health-related quality of life and lower pain intensity and catastrophizing (P<0.05), supporting convergent validity of the scale. There was a statistically significant increase in FC-CPSES scores between pre- and postintervention measures for both versions of the FC-CPSES (P<0.003), which supports their sensitivity to clinical change during an intervention.CONCLUSIONS: These data suggest that both versions of the FC-CPSES are reliable and valid for the measurement of pain management self-efficacy among chronic pain patients.
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Rahmayati, Y., F. Vanini, L. Rahmayani, R. Hendarti, W. Aghamdi, P. Andriany, I. Sundari, C. F. Novita i P. A. Sofya. "Designing the temporary dental clinic in the Covid-19 global pandemic". IOP Conference Series: Earth and Environmental Science 1026, nr 1 (1.05.2022): 012023. http://dx.doi.org/10.1088/1755-1315/1026/1/012023.

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Abstract Covid-19 pandemic has directed hospitals to concentrate services for patients who are positive or still in undefined status. Some countries are even forced to build temporary structures or utilize multifunctional buildings such as sports/public halls. On the other hand, hospitals still have to keep performing other routine services and this becomes a challenge for them. When global attention nowadays focuses more on how hospitals serve the Covid-19 cases, this research proposes another side of healthcare service needed by people in the pandemic, which is the dental clinic. The spread of Covid-19 through droplets puts both dental patients and practitioners at risk target of Covid-19 transmission. Therefore, particular standards and protocols are mandatory to be deployed. A prototype design of the temporary dental clinic is the main output from this research. The main objective is to provide service for the community without being afraid of contracting the pandemic as the clinic will be isolated from the regular hospital buildings. To achieve this objective, this research employed three approaches for the methodology. It was started with the desk study to review references on recent technology of temporary building structures. Followed by the online questionnaire using the Google platform distributed to 206 registered dental practitioners in Aceh, in collaboration with the Indonesian Dental Association, Aceh Province, Indonesia. The questionnaire collected the data related to the needs, standards, procedures, and dental service protocols under the Covid-19 pandemic as the main reference for the design process. The last approach was gathering feedback from dentists and international architects who are experts in building science and technology. This was done through a series of pre-design reviews. This research has a high degree of urgency globally, including Saudi Arabia, which is also impacted by the Covid-19 pandemic. It is also in line with Saudi Vision 2030 to enhance the standard quality and sustainability of healthcare services. The prototype design proposed in this research does not only contribute to the Covid-19 pandemic in particular but also post-Covid scenarios or other possible global pandemics in the future.
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Agostino, Holly, i Brett Burstein. "104 New Presentations of Anorexia Nervosa and Atypical Anorexia Nervosa In Adolescents During the COVID-19 Pandemic". Paediatrics & Child Health 26, Supplement_1 (1.10.2021): e74-e74. http://dx.doi.org/10.1093/pch/pxab061.084.

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Abstract Primary Subject area Adolescent Medicine Background The coronavirus (COVID-19) pandemic has had profound effects on adolescent mental health. Beginning in mid-March 2020, public health measures were implemented throughout the province of Quebec, including full school closure and confinement. Previous studies have demonstrated the association between stressful events and the exacerbation of anorexia nervosa (AN), however the association of the COVID-19 pandemic on new AN diagnoses remains unknown. Objectives To assess the incidence and severity of newly diagnosed AN or atypical AN (AAN) cases among adolescents during the COVID-19 pandemic compared to the five preceding years. Design/Methods We performed a retrospective analysis from Jan 1 2015 to Nov 15 2020 of new eating disorder assessments at an urban tertiary pediatric hospital. Baseline demographic information and clinical assessment variables were collected. The primary outcomes were the incidence of de novo AN or AAN diagnoses and hospitalization within 7 days of diagnosis. Event rate time trends were compared during the period of pandemic public health measures (March 2020 to November 2020) to the proceeding 5-years (January 2015 to February 2020) using an interrupted time series and logistic mixed modeling. Results Overall, 353 patients met inclusion criteria during the study period. Median patient age was 15.9 (IQR 13.8-16.9) years, 93% were female, and 65% of patients were diagnosed with atypical AN. For the full cohort at diagnosis, %mBMI was 92% (SD ±15%) and mean weight loss was 11 Kg (SD ±7Kg). In the 5 years preceding the pandemic, there were 4.5 new AN/AAN cases per month with a modest downward trend (ßcoeff=-0.016). During confinement, new diagnoses rose to 8.0/month with a steep upward trend (ßcoeff=1.417, p &lt; 0 .001). Similarly, hospitalizations for new cases increased from 0.8 to 2.6/month with a significant increase in linear tend (ßcoeff -0.012 vs. 0.500, p &lt; 0 .001). Moreover, patients diagnosed during COVID-19 confinement had a shorter duration of symptoms (6 months vs. 10 months, p=0.001), with a higher percentage of body weight loss (19% vs. 16%, p=0.03) at a faster rate (2.3kg/mo vs. 1.5Kg/mo, p=0.001). Bradycardia was more pronounced at diagnosis during the pandemic (55 bpm vs. 62 bpm, p=0.001) with a greater proportion meeting threshold for admission (38% vs. 19%, p=0.001). Conclusion During the COVID-19 confinement, new diagnoses of AN and AAN nearly doubled and hospitalizations for these patients more than tripled. Markers for disease severity were more pronounced and evolved more rapidly. Findings highlight the urgent need for increased community resources during the pandemic, as well as prospective research to understand drivers and prognosis for these patients more effectively.
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Sinclair, Douglas, Peter Toth, Alecs Chochinov, John Foote, Kirsten Johnson, Jill McEwen, David Messenger i in. "Health human resources for emergency medicine: a framework for the future". CJEM 22, nr 1 (26.11.2019): 40–44. http://dx.doi.org/10.1017/cem.2019.446.

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ABSTRACTIn June of 2016, the Collaborative Working Group (CWG) on the Future of Emergency Medicine presented its final report at the Canadian Association of Emergency Physicians (CAEP) annual meeting in Quebec City. The CWG report made a number of recommendations concerning physician Human Health Resource (HHR) shortfalls in emergency medicine, specific changes for both the Royal College of Physicians and Surgeons of Canada (FRCPC) and the College of Family Physicians of Canada (CCFP-EM) training programs, HHR needs in rural and remote hospitals, future collaboration of the CCFP-EM and FRCPC programs, and directions for future research. All recommendations were endorsed by CAEP, the Royal College of Physicians and Surgeons of Canada (RCPSC), and the College of Family Physicians of Canada (CFPC). The CWG report was published in CJEM and has served as a basis for ongoing discussion in the emergency medicine community in Canada. The CWG identified an estimated shortfall of 478 emergency physicians in Canada in 2016, rising to 1071 by 2020 and 1518 by 2025 assuming no expansion of EM residency training capacity. In 2017, the CAEP board struck a new committee, The Future of Emergency Medicine in Canada (FEMC), to advocate with appropriate stakeholders to implement the CWG recommendations and to continue with this important work. FEMC led a workshop at CAEP 2018 in Calgary to develop a regional approach to HHR advocacy, recognizing different realities in each province and region. There was wide representation at this workshop and a rich and passionate discussion among those present. This paper represents the output of the workshop and will guide subsequent deliberations by FEMC. FEMC has set the following three goals as we work toward the overarching purpose to improve timely access to high quality emergency care: (1) to define and describe categories of emergency departments (EDs) in Canada, (2) define the full time equivalents required by category of ED in Canada, and (3) recommend the ideal combination of training and certification for emergency physicians in Canada. A fourth goal supports the other three goals: (4) urge further consideration and implementation of the CWG-EM recommendations related to coordination and optimization of the current two training programs. We believe that goals 1 and 2 can largely be accomplished by the CAEP annual meeting in 2020, and goal 3 by the CAEP annual meeting in 2021. Goal 4 is ongoing with both the RCPSC and the CFPC. We urge the EM community across Canada to engage with our committee to support improved access and EM care for all Canadians.
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Brière, Raphaëlle, Rogeh Habashi, Shaila Merchant, Lina Cadili, Zainab Alhumoud, Rebecca Lau, Nada Gawad i in. "2023 Canadian Surgery Forum01. Evaluation of physicians’ practices and knowledge regarding the treatment of acute uncomplicated diverticulitis03. What is the effect of rurality on outcomes for parathyroidectomy in a large North American jurisdiction?05. Characteristics of opioid providers for patients undergoing same-day breast surgery in Ontario, Canada06. Improving the management and outcomes of complex non-pedunculated colorectal polyps at a regional hospital in British Columbia10. Actinomycosis presenting as an anterior abdominal mass after laparoscopic cholecystectomy12. Prioritizing melanoma surgeries to prevent wait time delays and upstaging of melanoma during the COVID-19 pandemic13. Trust me, I know them: assessing interpersonal bias in general surgery residency interviews14. Current state of female and BIPOC representation in Canadian academic surgical societies15. Harnessing a province-wide network of surgical excellence and diverse talents for the continuous improvement of surgical care in BC16. Massive stone or is it glass: a curious case of porcelain gallbladder17. Choosing your endoscopist: a retrospective single-centre cohort study18. The local experience with endoscopic ampullectomy for noninvasive ampullary lesions at a single tertiary care centre19. Defining appropriate intraoperative patient blood management strategies in noncardiac surgery: the Ottawa Intraoperative Transfusion Consensus20. Postoperative gastrointestinal dysfunction after neuromuscular blockade reversal with sugammadex versus cholinesterase inhibitors in patients undergoing gastrointestinal surgery: a systematic review and meta-analysis21. Factors influencing recurrence in medial breast cancer after skin-sparing mastectomy and immediate breast reconstruction22. What is the role of fit in medical education? A scoping review23. 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Antibiotic prophylaxis and mechanical bowel preparation in elective colorectal surgery: a survey of Quebec general surgeons36. Identifying core deficiencies and needs in the surgical knot-tying curriculum: a single-centre qualitative analysis37. Spleen-preserving surgery for symptomatic benign splenic cyst: video case report38. Learning to manage power differentials and navigate uncertainty: a qualitative interview study about decision-making in surgery39. Surgical education checklist: a novel tool to improve uptake of Competence By Design in a residency program and surgical resident experience40. A comparative evaluation of management strategies and patient outcomes for acute appendicitis in the post-COVID era41. External benchmarking of colorectal resection outcomes using ACS-NSQIP: accurately categorizing procedures at risk of morbidity42. Role of thymectomy in surgical treatment of secondary and tertiary hyperparathyroidism43. Starting position during colonoscopy: a systematic review and meta-analysis of randomized controlled trials44. Enhanced Recovery After Surgery protocols following emergency intra-abdominal surgery reduces length of stay and postoperative morbidity: a systematic review and meta-analysis45. Competencies, privileging and geography: preparing general surgery residents for rural practice in British Columbia46. Holographic surgical skills training: Can we use holograms to teach hand ties and is it comparable to in-person learning?47. The association between gender and confidence in UBC general surgery residents48. Quality improvement in timeliness of EPA completion in general surgery residency49. Gastrointestinal system surgical outcomes in the highly active antiretroviral therapy (HAART)-era HIV-positive patient: a scoping review50. Joint rounds as a method to partner surgical residency programs and enhance global surgical training52. Preoperative frailty and mortality in medicare beneficiaries undergoing major and minor surgical procedures53. What’s going on out there? Evaluating the scope of rural general surgery in British Columbia54. Short-stay compared with long-stay admissions for loop ileostomy reversals: a systematic review and meta-analysis55. General surgeons’ right hemicolectomy costs proficiency and preferences56. Staple line with bioabsorbable reinforcement for gastropexy in hiatal hernia repair57. Impact of enhanced recovery pathways on patient-reported outcomes after abdominal surgery: a systematic review58. Evaluation of outcomes between rural, northern/remote, and urban surgical patients diagnosed with moderate to severe acute pancreatitis: a retrospective study59. Outcome of preoperative percutaneous drainage of intraabdominal abscess versus initial surgery in patients with Crohn disease60. Preliminary analysis: dexamethasone-supplemented TAP blocks may reduce opioid requirements after colorectal surgery: a multi-centre randomized controlled trial61. Preoperative skin preparation with chlorhexidine alcohol versus povidone–iodine alcohol for the prevention of surgical site infections: a systematic review and meta-analysis of randomized controlled trials62. “Why didn’t you call me?” Factors junior learners consider when deciding whether to call their supervisor63. Cost savings associated with general surgical consultation within remote Indigenous communities in Quebec: a costing evaluation64. Right lateral decubitis patient position during colonoscopy increases endoscopist’s risk of musculoskeletal injury65. Reducing re-visit to hospital rates among pediatric post-appendectomy patients: a quality-improvement project66. Exploring gender diversity in surgical residency leadership across Canada67. Operating room sustainability project: quantifying the surgical environmental footprint for a laparoscopic cholecystectomy in 2 major surgical centres68. ERCP under general anesthesia compared with conscious sedation (EUGACCS) study69. Complications requiring intervention following gastrostomy/gastrojejunostomy tube insertion: a retrospective analysis70. Equity, diversity and inclusion (EDI) in underrepresented in medicine (URiM) residents: Where are we and what now?71. Association between complications and death within 30 days after general surgery procedures: a Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) substudy72. What is the long-term impact of gastrograffin on adhesive small bowel obstruction? A systematic narrative review73. TRASH-CAN: Trainee-Led Research and Sudit for Sustainability in Healthcare Canada74. Representation and reporting of sociodemographic variables in BREAST-Q studies: a systematic review75. A scoping review: should tap water instead of sterile water be used for endoscopy of the colon and rectum?76. Laparoscopic revision of Nissen fundoplication with EndoFLIP intraoperative assistance: a video presentation77. Environmental sustainability in the operating room: perspectives and practice patterns of general surgeons in Canada78. The impact of COVID-19 on medical students applying to general surgery in the CaRMS matching process79. Novel approach to laparoscopic gastrostomy tube placement80. Using prucalopride for prevention of postoperative ileus in gastrointestinal surgery: a systematic review and meta-analysis of randomized controlled trials81. Assessment of environmental and economic sustainability of perioperative patient warming strategies83. Development of a Canadian colorectal robotic surgery program: the first three years84. Patient safety and quality improvement lessons from review of Canadian thyroid and parathyroid surgery malpractice litigation case law01. Changes in sarcopenia status predict survival among patients with resectable esophageal cancer02. The feasibility of near-infrared fluorescence-guided robotic-assisted minimally invasive esophagectomy using indocyanine green dye03. Does patient experience with robotic thoracic surgery influence their willingness to pay for it?04. Artificial intelligence–augmented endobronchial ultrasound-elastography is a useful adjunct for lymph node staging for lung cancer05. Preoperative mediastinal staging in early-stage lung cancer: targeted nodal sampling is not inferior to systematic nodal sampling06. The application of an artificial intelligence algorithm to predict lymph node malignancy in non-small cell lung cancer07. Pneumonectomy for non-small cell lung cancer: long-term overall survival from a 15-year experience09. Primary spontaneous pneumothorax occurred in pectus excavatum patients10. Optimizing management for early-stage esophageal adenocarcinoma: longitudinal results from a multidisciplinary program11. Needle decompressions in post-traumatic tension pneumothorax: boon or bane12. 10-year follow-up of endoscopic mucosal resection versus esophagectomy for esophageal intramucosal adenocarcinoma in the setting of Barrett esophagus: a Canadian experience13. Outcomes after thoracic surgery for malignancy in patients with severe and persistent mental illness15. Stage II/III esophageal cancer patients with complete clinical response after neoadjuvant chemoradiotherapy: a Markov decision analysis16. Development of a surgical stabilization of rib fractures program at a Level I trauma centre in Qatar: initial report17. Screening Criteria Evaluation for Expansion in Pulmonary Neoplasias (SCREEN) II18. Multi-centre study evaluating the risks and benefits of intraoperative steroids during pneumonectomy19. Prediction of esophageal cancer short-term survival using a pretreatment health-related quality of life measure20. Evaluating the impact of virtual care in thoracic surgery: patients’ perspective21. Virtual thoracic surgical outpatient encounters are non-inferior to in-person visits for overall patient care satisfaction in the post-COVID-19 era22. Concurrent minimally invasive esophagectomy and laparoscopic right hemicolectomy23. Assessing the impact of robotic-assisted thoracic surgery on direct carbon dioxide emissions — a retrospective analysis of a prospective cohort24. Young’s modulus of human lung parenchyma and tumours25. Thoracic surgery trauma: nail gun v. SVC26. Thymomatous myasthenia gravis after total thymectomy at a tertiary care surgical centre: a 15-year retrospective review27. Effectiveness of 18F-FDG-PET/CT in the stage diagnosis of non-small cell lung cancer (NSCLC): a diagnostic test accuracy systematic review and meta-analysis01. Emergency colon resection in the geriatric population: the modified frailty score as a risk factor of early mortality02. Laparoscopic ovarian transposition prior to pelvic radiation in young female patients with anorectal malignancies: a systematic review and meta-analysis of prevalence03. Using preoperative C-reactive protein levels to predict anastomotic leaks and other complications after elective colorectal surgery: a systematic review and meta-analysis04. Perioperative intravenous dexamethasone for patients undergoing colorectal surgery: a systematic review and meta-analysis05. Population-based study comparing time from presentation to diagnosis and treatment between younger and older adults with colorectal cancer06. The role of warmed-humidified CO2insufflation in colorectal surgery: a meta-analysis07. Total abdominal colectomy versus diverting loop ileostomy and antegrade colonic lavage for fulminantClostridioidescolitis: analysis of the national inpatient sample 2016–201908. Cutting seton for the treatment of cryptoglandular fistula-inano: a systematic review and meta-analysis09. Prognostic value of routine stain versus elastic trichrome stain in identifying venous invasion in colon cancer10. Anastomotic leak rate following the implementation of a powered circular stapler in elective colorectal surgeries11. Surgical technique and recurrence of Crohn disease following ileocolic resection12. Implementation of synoptic reporting for endoscopic localization of complex colorectal neoplasms: Can we reduce rates of repeat preoperative colonoscopy?13. Effects of diet and antibiotics on anastomotic healing: a mouse model study with varied dietary fibre and fat, and preoperative antibiotics14. Assessment of rectal surgery–related physical pain and conditioning: a national survey of Canadian rectal surgeons15. Does specimen extraction incision and transversus abdominis plane block affect opioid requirements after laparoscopic colectomy?16. Colorectal and therapeutic GI working together: What is the role for TAMIS for benign lesions?17. Impact of the COVID-19 pandemic on readmission rates following colorectal surgery18. More than the sum of its parts: the benefits of multidisciplinary conferences extend beyond patient care19. Multidisciplinary conference for rectal cancer — measuring patient care impact20. Patient outcomes in emergency colorectal cancer resections: a 15-year cohort analysis21. Enhanced Recovery after Surgery (ERAS) protocols in colorectal cancer resection: a 15-year analysis of patient outcomes22. Laparoscopic to open conversion in colorectal cancer resection: a 15-year analysis of postoperative outcomes23. Management of postoperative ileus in colorectal cancer resections: a 15-year evaluation of patient outcomes24. Timing of ostomy reversal and associated outcomes: a systematic review25. Fragility of statistically significant outcomes in colonic diverticular disease randomized trials26. Postoperative day 1 and 2 C-reactive protein values for predicting postoperative morbidity following colorectal surgery27. Bariatric surgery before colorectal surgery reduces postoperative morbidity and health care resource utilization: a propensity score matched analysis28. Ileocolic Crohn disease: a video vignette of the Kono-S anastomosis29. Association between patient activation and postoperative outcomes in rectal cancer survivors30. Understanding surgeon and nurse perspectives on the use of patient-generated data in the management of low anterior resection syndrome31. Characteristics of interval colorectal cancer: a Canadian retrospective population-level analysis from Newfoundland and Labrador32. Current rectal cancer survivorship care: unmet patient needs and fragmented specialist and family physician care33. Local excision for T1 rectal cancer: a population-based study of practice patterns and oncological outcomes34. Can nonoperative management of acute complicated diverticulitis be successfully treated with a future hospital at home program? A retrospective cohort study35. Does patient activation impact remote digital health follow-up and same-day discharge after elective colorectal surgery36. Parastomal hernia prevention, assessment and management: best practice guidelines37. Anastomotic leak rates in circular powered staplers versus manual circular staplers in left sided colorectal anastomoses: a systematic review38. The Gips procedure for pilonidal disease: a video presentation39. Local recurrence-free survival after transanal total mesorectal excision: a Canadian institutional experience40. The impact of operative approach for obese colorectal cancer patients: analysis of the national inpatient sample (2015–2019)41. Safety and feasibility of discharge within 24 hours of colectomy: a systematic review and meta-analysis42. Laparoscopic lateral lymph node dissection for an advanced rectal cancer: a video abstract43. “Dear diary”: challenges in adopting routine operative recording in surgical training44. Rectal cancer in the very young (age < 40) — more treatment, worse survival: a population-based study45. Surveillance following treatment for stage I–III rectal cancer in Ontario — a population-based descriptive study46. A 15-year institutional experience of trananal endoscopic microsurgery for local excision of benign and malignant rectal neoplasia47. Robotic approach to reoperative pelvic surgery48. A mucosa-adherent bacterium impairs colorectal anastomotic healing by upregulating interleukin-17: the role of low-grade inflammation as a driver of anastomotic leak49. High uptake of total neoadjuvant therapy for rectal cancer in Canada despite surgeon concerns for possible overtreatment and treatment-related toxicity50. Safety and feasibility of discharge within 24 hours of ileostomy reversal: a systematic review and meta-analysis51. Safety and efficacy of intravenous antifibrinolytic use in colorectal surgery: systematic review and meta-analysis52. Impact of ileal pouch anal anastomosis on fertility in female patients with uulcerative colitis: a systemic review53. Modulation of the gut microbiota with fermentable fibres and 5-aminosalicylate to prevent peri-anastomotic and metastatic recurrence of colorectal cancer54. Patients with locally advanced rectal cancer and a non-threatened circumferential resection margin may go straight to surgery and avoid radiation toxicities: the QuickSilver Trial55. Colonoscopies during the COVID-19 pandemic recovery period: Are we caught up on colorectal cancer detection and prevention? A single-institution experience56. Interim results of a phase II study evaluating the safety of nonoperative management for locally advanced low rectal cancer57. Assessing a tailored curriculum for endoscopic simulation for general surgery residency programs in Canada58. Modified Frailty Index for patients undergoing surgery for colorectal cancer: analysis of the National Inpatient Sample (2015–2019)59. Reducing postoperative bloodwork in elective colorectal surgery: a quality-improvement initiative60. A Nationwide Readmission Database (NRD) analysis assessing timing of readmission for complications following emergency colectomy: why limiting follow-up to postoperative day 30 underserves patients61. The same but different: clinical and Enhanced Recovery After Surgery outcomes in right hemicolectomy for colon cancer versus ileocecal resection in Crohn disease01. How reliable are postmastectomy breast reconstruction videos on YouTube?02. Knowledge, perceptions, attitudes, and barriers to genetic literacy among surgeons: a scoping review03. Exploring neutrophil-to-lymphocyte ratio as a predictor of postoperative breast cancer overall survival04. High β integrin expression is differentially associated with worsened pancreatic ductal adenocarcinoma outcomes05. Epidemiology of undifferentiated carcinomas06. An evidence-based approach to the incorporation of total neoadjuvant therapy into a standardized rectal cancer treatment algorithm07. Pushing the boundaries: right retroperitoneoscopic adrenalectomy after laparoscopic right nephrectomy08. The role of caspase-1 in triple negative breast cancer, the immune tumour microenvironment and response to anti-PD1 immunotherapy09. Perioperative neutrophil-to-lymphocyte ratio is associated with survival in patients undergoing colorectal cancer surgery10. Achievement of quality metrics in older adults undergoing elective colorectal cancer surgery11. Opportunities to improve the environmental sustainability of breast cancer surgical care12. Does margin status after biopsy matter in melanoma? A cohort study of micro- and macroscopic margin status and their impact on residual disease and survival13. Demonstration of D2 Lymph node stations during laparoscopic total gastrectomy14. Incidence of metastatic tumours to the ovary (Krukenberg) versus primary ovarian neoplasms associated with colorectal cancer surgery15. Spatial biomarkers in cancer16. How informed is the consent process for complex cancer resections?17. Adjuvant radiation therapy among immigrant and Canadian-born/long-term resident women with breast cancer18. Human peritoneal explant model reveals genomic alterations that facilitate peritoneal implantation of gastric cancer cells19. Preoperative breast satisfaction association with major complications following oncologic breast surgery20. Impact of geography on receipt of medical oncology consultation and neoadjuvant chemotherapy for triple negative andHER2positive breast cancer21. Comparison of radiation, surgery or both in women with breast cancer and 3 or more positive lymph nodes22. Impact of synoptic operative reporting as a quality indicator for thyroid surgery: a Canadian national study01. The Toronto management of initially unresectable liver metastases from colorectal cancer in a living donor liver transplant program02. Dissection of a replaced right hepatic artery arising from the superior mesenteric artery during a laparoscopic Whipple03. Implementing the HIBA index: a low-cost method for assessing future liver remnant function04. Oncologic outcomes after surgical resection versus thermoablation in early-stage hepatocellular carcinoma: a systematic review of randomized controlled trials with meta-analysis05. Robotic pancreatic necrosectomy and internal drainage for walled-off pancreatic necrosis06. Predicting diabetes mellitus after partial pancreatectomy: PRIMACY, a pilot study07. Bleed and save: patient blood management in hepatectomy08. Defining standards for hepatopancreatobiliary cancer surgery in Ontario, Canada: a population-based cohort study of clinical outcomes09. Laparoscopic choledochoduodenostomy for recurrent choledocholithiasis10. A comparison of daytime versus evening versus overnight liver transplant from a single Canadian centre11. Pilot study validating the line of safety as a landmark for safe laparoscopic cholecystectomy using indocyanine green and near-infrared imagine12. Effect of transversus abdominis plane catheters on postoperative opioid consumption in patients undergoing open liver resections — a single-centre retrospective review13. Comparing the RETREAT score to the Milan criteria for predicting 5-year survival in post-liver transplant hepatocellular carcinoma patients: a retrospective analysis14. Characterizing the effect of a heat shock protein-90 inhibitor on porcine liver for transplantation using ex-vivo machine perfusion15. Modulation by PCSK9 of the immune recognition of colorectal cancer liver metastasis17. Implementation of a preoperative ketogenic diet for reduction of hepatic steatosis before hepatectomy19. Trends in the incidence and management of hepatocellular carcinoma in Ontario20. Canadian coaching program leads to successful transition from open to laparoscopic hepatopancreatobiliary surgery21. The impact of a positive pancreatic margin analyzed according to LEEPP on the recurrence and survival of patients with pancreatic head adenocarcinoma22. Armed oncolytic virus VSV-LIGHT/TNFSF14 promotes survival and results in complete pathological and radiological response in an immunocompetent model of advanced pancreatic cancer23. Comparing the efficacy of cefazolin/metronidazole, piperacillin-tazobactam, or cefoxitin as surgical antibiotic prophylaxis in patients undergoing pancreaticoduodenectomy: a retrospective cohort study01. Not just jumping on the bandwagon: a cost-conscious establishment of a robotic abdominal wall reconstruction program in a publicly funded health care system02. Shouldice method brief educational video03. Laparoscopic recurrent hiatal hernia repair with mesh gastropexy04. Robotic transabdominal preperitoneal Grynfeltt lumbar hernia repair with mesh01. Substance abuse screening prior to bariatric surgery: an MBSAQIP cohort study evaluating frequency and factors associated with screening02. MBSAQIP risk calculator use in elective bariatric surgery is uncommon, yet associated with reduced odds of serious complications: a retrospective cohort analysis of 210 710 patients03. Short-term outcomes of concomitant versus delayed revisional bariatric surgery after adjustable gastric band removal04. Safety and outcomes of bariatric surgery in patients with inflammatory bowel disease: a systematic review and meta-analysis08. Prescription drug usage as measure of comorbidity resolution after bariatric surgery — a population-based cohort study09. Experiences and outcomes of Indigenous patients undergoing bariatric surgery: a mixed-methods scoping review10. Bariatric surgery reduces major adverse kidney events in patients with chronic kidney disease: a multiple-linked database analysis in Ontario11. Inter-rater reliability of indocyanine green fluorescence angiography for blood flow visualization in laparoscopic Roux-en-Y gastric bypass12. Characterization of small bowel obstructions following elective bariatric surgery13. Revision of bariatric surgery for gastroesophageal reflux disease: characterizing patient and procedural factors and 30-day outcomes for a retrospective cohort of 4412 patients14. Duodenal-jejunal bypass liners are superior to optimal medical management in ameliorating metabolic dysfunction: a systematic review and meta-analysis15. Characteristics and outcomes for patients undergoing revisional bariatric surgery due to persistent obesity: a retrospective cohort study of 10 589 patients01. Collateral damage: the impact of the COVID-19 pandemic on the severity of abdominal emergency surgery at a regional hospital02. Pseudoaneurysms after high-grade penetrating solid organ injury and the utility of delayed CT angiography03. Pseudoaneurysm screening after pediatric high-grade solid organ injury04. Witnessed prehospital traumatic arrest: predictors of survival to hospital discharge05. A tension controlled, noninvasive device for reapproximation of the abdominal wall fascia in open abdomens08. Delayed vs. early laparoscopic appendectomy (DELAY) for adult patients with acute appendicitis: a randomized controlled trial09. Days at home after malignant bowel obstructions: a patient-centred analysis of treatment decisions10. Polytrauma and polyshock: prevailing puzzle11. National emergency laparotomy audit: a 9-year evaluation of postoperative mortality in emergency laparotomy13. A comparison of stress response in high-fidelity and low-fidelity trauma simulation14. ASA versus heparin in the treatment of blunt cerebrovascular injury — a systematic review and meta-analysis15. Comparison of complication reporting in trauma systems: a review of Canadian trauma registries16. Benefits of the addition of a nurse practitioner to a high-volume acute care surgery service: a quantitative survey of nurses, residents and surgery attendings17. Examining current evidence for trauma recurrence preventions systems18. Disparities in access to trauma care in Canada: a geospatial analysis of Census data19. Fast-track pathway to accelerated cholecystectomy versus standard of care for acute cholecystitis: the FAST pilot trial20. Using the modified Frailty Index to predict postoperative outcomes in patients undergoing surgery for adhesive small bowel obstruction: analysis of the National Inpatient Sample, 2015–201921. Adequacy of thromboprophylaxis in trauma patients receiving conventional versus higher dosing regimens of low-molecular-weight heparin: a prospective cohort study22. The hidden epidemiology of trauma in Nunavik: a comparison of trauma registries as a call to action23. Mapping surgical services in rural British Columbia: an environmental scan". Canadian Journal of Surgery 66, nr 6 Suppl 1 (8.12.2023): S53—S136. http://dx.doi.org/10.1503/cjs.014223.

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Chandler, Vincent, i Maryam Dilmaghani. "Competition and childcare quality: Evidence from Quebec". Journal of Social Policy, 20.06.2023, 1–26. http://dx.doi.org/10.1017/s0047279423000314.

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Abstract Since 1997, the Canadian province of Quebec has put in place a heavily subsidized universal childcare program for all children under the school age. The present paper examines how the level of competition among individual providers associates with the quality of childcare in Quebec. The quality of childcare is measured by the number of violations and penalties recorded in the inspections conducted by the Quebec Ministry of Family Affairs. The analysis indicates that the intensity of parental competition for daycare spots, as opposed to childcare centres’ competition to attract parents, negatively associates with the quality of childcare. Critically, this association is mainly driven by less affluent neighbourhoods. In addition, these associations are found to be stronger for more serious violations. The policy implications for both childcare quality and childcare equality are discussed.
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Lefebvre, Gabrielle, Slim Haddad, Dominique Moncion-Groulx, Mélanie Saint-Onge i André Dontigny. "Socioeconomic disparities and concentration of the spread of the COVID-19 pandemic in the province of Quebec, Canada". BMC Public Health 23, nr 1 (6.06.2023). http://dx.doi.org/10.1186/s12889-023-15983-3.

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Abstract Background Recent studies suggest that the risk of SARS-CoV-2 infection may be greater in more densely populated areas and in cities with a higher proportion of persons who are poor, immigrant, or essential workers. This study examines spatial inequalities in SARS-CoV-2 exposure in a health region of the province of Quebec in Canada. Methods The study was conducted on the 1206 Canadian census dissemination areas in the Capitale-Nationale region of the province of Quebec. The observation period was 21 months (March 2020 to November 2021). The number of cases reported daily in each dissemination area was identified from available administrative databases. The magnitude of inequalities was estimated using Gini and Foster-Greer-Thorbecke (FGT) indices. The association between transmission and socioeconomic deprivation was identified based on the concentration of transmission in socially disadvantaged areas and on nonparametric regressions relating the cumulative incidence rate by area to ecological indicators of spatial disadvantage. Quantification of the association between median family income and degree of exposure of dissemination areas was supplemented by an ordered probit multiple regression model. Results Spatial disparities were elevated (Gini = 0.265; 95% CI [0.251, 0.279]). The spread was more limited in the less densely populated areas of the Quebec City agglomeration and outlying municipalities. The mean cumulative incidence in the subsample made up of the areas most exposed to the pandemic was 0.093. The spread of the epidemic was concentrated in the most disadvantaged areas, especially in the densely populated areas. Socioeconomic inequality appeared early and increased with each successive pandemic wave. The models showed that areas with economically disadvantaged populations were three times more likely to be among the areas at highest risk for COVID-19 (RR = 3.55; 95% CI [2.02, 5.08]). In contrast, areas with a higher income population (fifth quintile) were two times less likely to be among the most exposed areas (RR = 0.52; 95% CI [0.32, 0.72]). Conclusion As with the H1N1 pandemics of 1918 and 2009, the SARS-CoV-2 pandemic revealed social vulnerabilities. Further research is needed to explore the various manifestations of social inequality in relation to the pandemic.
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Austin, Nichole, David Rudoler, Sara Allin, Lisa Dolovich, Richard H. Glazier, Agnes Grudniewicz, Elisabeth Martin, Caroline Sirois i Erin Strumpf. "Team-based primary care reforms and older adults: a descriptive assessment of sociodemographic trends and prescribing endpoints in two Canadian provinces". BMC Primary Care 24, nr 1 (10.01.2023). http://dx.doi.org/10.1186/s12875-022-01960-z.

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Abstract Background Team-based primary care reforms aim to improve care coordination by involving multiple interdisciplinary health professionals in patient care. Team-based primary care may support improved medication management for older adults with polypharmacy and multiple points of contact with the healthcare system. However, little is known about this association. This study compares sociodemographic and prescribing trends among older adults in team-based vs. traditional primary care models in Ontario and Quebec. Methods We constructed two provincial cohorts using population-level health administrative data from 2006–2018. Our primary exposure was enrollment in a team-based model of care. Key endpoints included adverse drug events (ADEs), potentially inappropriate prescriptions (PIPs), and polypharmacy. We plotted prescribing trends across the observation period (stratified by model of care) in each province. We used standardized mean differences to compare characteristics of older adults and providers, as well as prescribing endpoints. Results Formal patient/physician enrollment increased in both provinces since the time of policy implementation; team-based enrollment among older adults was higher in Quebec (47%) than Ontario (33%) by the end of our observation period. The distribution of sociodemographic characteristics was reasonably comparable between team-based and non-team-based patients in both provinces, aside from a persistently higher share of rural patients in team-based care. Most PIPs assessed either declined or remained relatively steady over time, regardless of model of care and province. Several PIPs were more common among team-based patients than non-team-based patients, particularly in Quebec. We did not detect notable trends in ADEs or polypharmacy in either province. Conclusions Our findings offer encouraging evidence that many PIPs are declining over time in this population, regardless of patients’ enrollment in team-based care. Rates of decline appear similar across models of care, suggesting these models may not meaningfully influence prescribing endpoints. Additional efforts are needed to understand the impact of team-based care among older adults and improve primary care prescribing practices.
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