Rozprawy doktorskie na temat „Primary shools”

The main purpose of this dissertation is to analyse why three New South Wales primary schools were successful in implementing and managing educational technology. Responding to this research focus four specific questions were considered: Why have these schools been successful in implementing and managing educational technology? What factors have helped and/or hindered the successful implementation and management of educational technology within the selected schools? What are the indicators of successful implementation of educational technology? What were the particular contributions of leadership to the successful implementation and management of educational technology within the selected schools? This qualitative research study is based on the assumption that valuable data are gathered by studying schools that have been successful with the implementation and management of technology. In particular, the study provided a description and analysis of the best practice in three New South Wales Primary schools that had successfully implemented and managed educational technology. An interactive and cyclical process of data analysis was employed with data collection, data analysis and theory development proceeding simultaneously. To reduce and display data gathered from in-depth interviews, document study and non- participant observation the qualitative data analysis program QSR NUD*IST was utilised. The development and validation of the study’s conceptual framework shaped the study leading to the formulation of the SupportIF Model of Implementation. This model posits that success with implementation and management of educational technology is closely related to the level of interdependence between the implementation factors. The study results also endorsed the prime importance of a supportive work environment in each of the studied schools and linked this environment to the level of success realised with the implementation and management of technology and the utilisation of educational technology to enhance the achievement of student learning outcomes. The study contends that the sustainability of a school based technology initiative rests with a school’s ability to dynamically balance the key implementation factors and to redesign in light of shared practice. Tantamount to this process is a supportive work environment in each school which is the critical variable that facilitates interdependence between leadership, resources, relationships and teaching and learning factors.

PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO
CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
Sob a perspectiva do design social, esta tese desenvolveu um sistema de projetação e produção distribuída (SPPD) que congrega a indústria e os meios de produção local como solução para a produção e distribuição de produtos (basicamente de segurança, higiene, proteção da saúde, auxilio na vida diária. vestuário, educação e lazer) de média complexidade para atenção básica em territórios diversos. A pesquisa iniciou pela revisão teórica sobre a dimensão da inovação tecnológica social (ITS) e as estratégias do design social para a formação de rede de atores sob a lógica da THDS (Tríplice Hélice Dupla complementares para a sustentabilidade). Na sequência, foi realizada uma investigação sobre as experiências projetuais do design social, brasileiras e holandesas, e as do movimento de tecnologia social no Brasil. Por fim, foi desenvolvido o SPPD que visa a união de empresas e artesãos para produção territorializada de forma a atender suas demandas utilizando recursos locais e assim impulsionar o desenvolvimento local. O SPPD valoriza a atuação governamental ou de agentes sociais como impulsionador da demanda, e depende da constituição de um capital social e produtivo com agentes locais, que se mostrou o maior desafio do sistema. Quando aplicado ao calçado escolar, o SPPD evidenciou o papel crucial do designer para atender os parâmetros da projetação e produção distribuída em função das particularidades de cada local.
From the perspective of social design, this thesis developed a designing and distributed manufacturing system (DDMS) that gathers industry and local tasks (crafts) as a solution for the manufacturing and distribution of products (basically of safety, hygiene, health protection, assistance daily, clothing, education and leisure) of medium complexity for basic care in different territories. The research started by the theoretical review of the social dimension of technological innovation (STI) and strategies of social design for the network structure of players under the logic of THDs (Triple Helix Twin to sustainability). Following these, an investigation was carried out about Brazilian and Dutch social design experiences, as well as movement of social technology in Brazil. In the end, it was developed the DDMS aiming at the union of companies and craftsmen to implement a territorialized production in order to meeting their demands using local resources and thus achieve local development. The DDMS values governmental action or social actors as demand drivers, and depends on the creation of social capital and manufacturing group with local actors, which proved to be the biggest challenge system. When applied to the scholar shoes issue, DDMS highlighted the crucial role of the designer to meeting the designing requirements and distributed manufacturing According to circumstances of each local.

The interest in the use of fiscal policy as an effective economic policy tool has been revived recently, since the global recession of 2008 hit the world. In spite of a large empirical literature, there remains substantial uncertainty about the size and even the direction of the effects of discretionary fiscal policy. This thesis seeks to investigate the macroeconomic effects of discretionary fiscal policy in the short term, highlighting several methodologies for identifying discretionary fiscal policy. In Chapters 2 and 3, we suggest a new instrument based on the narrative approach for identifying exogenous government spending shocks: natural disaster damages and the subsequent government emergency spending. While applying our methodology to the Korean and the U.S data, we find that our instrument is not only powerful but also superior to military build-ups used by most of the literature. The relief expenditure in the wake of natural disaster has several advantages such as the similarity in scope to general government activity and the easy applicability beyond the U.S. compared to military build-ups. In the analysis of Korean fiscal policy, using our narrative method and the Structural Vector Autoregression (SVAR) model, we find that government spending shocks increase GDP, consumption, and real wage, which is in line with the New Keynesian model. We also find that the timing is crucial in identifying government spending shocks due to the anticipation effects of fiscal policy. Furthermore, while analyzing the U.S. fiscal policy both at the state as well as national level, we estimate two kinds of non-defense spending multipliers: federal (1.4~1.7) and state (1.5~2.5), which exceed the defense spending multiplier obtained in the literature using military building-ups. In Chapter 4, in regard to the study of effects of fiscal adjustment, we develop the approach based on changes in cyclically adjusted primary balance (CAPB) by including fluctuations of asset price in the CAPB measure and allowing for individual country heterogeneity in the definition of fiscal adjustment. Using our new CAPB in 20 OECD countries, we find that fiscal adjustments have contractionary effects on economic activity in the short term, which is consistent with the result based on the narrative approach. Nevertheless, our results suggest that fiscal adjustments that rely predominantly on spending cuts are less contractionary than those involving tax increases.

How should Australian criminal trial courts treat evidence deriving from illegally or improperly obtained evidence? The fact that derivative evidence gives rise to factors distinct from primary evidence makes it deserving of an examination of its peculiarities. In doing so, the assumption may be put aside that derivative evidence falls wholly within the established general discourse of illegally or improperly obtained evidence. Just as the judicial response to primary evidence must be intellectually rigorous, disciplined and principled, so must be the response to derivative evidence. As such, a principled analysis of how Australian courts should approach derivative evidence can significantly contribute to the discourse on the law with respect to the exclusion of illegally or improperly obtained evidence. This thesis provides that principled analysis by arguing that the principles which underpin and inform the discretionary exclusionary frameworks within Australia require an approach which is consistent as between illegally obtained derivative evidence and illegally obtained primary evidence.

La première partie de la thèse se compose d'une recherche empirique visant à examiner si les producteurs de produits primaires s'adaptent mieux après un choc d'offre sous un régime de taux de change flottant. À l'aide d'un modèle VAR, j'ai trouvé que les régimes de taux de change flexible n'effectuent pas mieux à isoler l'économie des chocs externes. Par conséquent, la deuxième partie de la thèse vise à établir ou non si les régimes de taux de change fournissent certains avantages pour les pays exportateurs de produits primaires tels que le fait d'attirer les investissements directs a l'étranger. À l'aide de différentes estimations économétriques, les résultats montrent que les régimes de taux de change influencent les investissements directs à l'étranger et en particulier, les régimes de change fixes plutôt que les régimes plus flexibles
The first part of dissertation consists of an empirical research aiming at investigating whether primary commodity producers perform better after a real shock with floating exchange rate regimes. Using a VAR model I found that flexible exchange rate regimes do not perform better at insulating the output from external shocks. Therefore, the second part of the dissertation aims at establishing whether or not exchange rate regimes provide certain benefit for those countries such as attracting foreign direct investments. Using panel data estimation techniques, I found that exchange rate regimes matters in attracting FDI and in particular fixed regimes rather than flexible regimes

Thesis (MNutr)--Stellenbosch University, 2012.
ENGLISH ABSTRACT: Introduction and Objectives: Schools can serve as a supportive environment for the promotion of healthy eating in order to prevent childhood overweight and obesity and the development of noncommunicable diseases such as cardiovascular diseases, type 2 diabetes mellitus, fatty liver disease, muscoskeletal disorders and some cancers. Tuck shops at schools often offer unhealthy items that are energy dense and high in fat and/or sugar with a low content of vitamins, minerals and dietary fibre. The availability of unhealthy items in tuck shops prevents learners from making healthy food choices, since children tend to choose unhealthy foods when given a choice. In addition to unhealthy items offered by tuck shops, learners also bring unhealthy items to school in their lunchboxes. The aim of the study was to investigate the influence of a nutritionally-regulated tuck shop on primary school learners’ perceptions, attitudes and behaviour towards healthy eating in a Bloemfontein, Afrikaans medium, co-education primary school, and compare it to learners of a school with a conventional tuck shop. Methods: In a cross-sectional survey with an analytical component, grade 2 to 7 learners in a school with a nutritionally-regulated tuck shop (n=116) and a school with a conventional tuck shop (n=141) completed a questionnaire. Six learners per grade also took part in focus group discussions. Questions related to lunchbox contents and perceptions, attitudes and behaviour towards the tuck shop and healthy eating. Nutritional information of the items available for purchase at each of the school tuck shops was collected. Results: The lunchboxes of learners in the school with a nutritionally-regulated tuck shop contained significantly (p<0.05) more healthy items (fruit, water and muffins), as well as significantly more unhealthy items (sweets and chips). The items offered by the nutritionally-regulated tuck shop contained approximately half the kilojoules compared to items offered by the conventional tuck shop. Learners in the school with a nutritionally-regulated tuck shop liked certain fruits and vegetables significantly (p<0.05) more than learners in the school with a conventional tuck shop. Statistical significant differences (p<0.05) between different grades and gender showed that grade 2 learners in both schools had a less positive attitude towards certain fruit and vegetables compared to the older learners, while girls in both schools were more positive towards certain fruits and vegetables compared to boys. Younger learners had a more positive attitude towards their nutritionally-regulated tuck shop than older learners. In both schools learners had similar perceptions regarding the particular school’s tuck shop and healthy eating. Conclusion: The hypothesis that learners in a school with a nutritionally-regulated tuck shop have positive attitudes, perceptions and behaviour towards healthy eating was rejected. The availability of healthier items in a school tuck shop had a positive influence on certain behaviours and attitudes of learners, but the potential value of controlling the type of items available for purchase at schools might be counteracted by lunchbox contents, certain fixed eating patterns, perceptions of learners and previous exposure to a conventional tuck shop. Recommendations include a multi-pronged approach such as the Health Promoting Schools concept.
AFRIKAANSE OPSOMMING: Inleiding en doelwitte: Skole bied ‘n omgewing waar goeie eetgewoontes bevorder kan word ten einde oorgewig en vetsug in kinders te voorkom, asook die ontwikkeling van nie-oordraagbare siektes soos kardiovaskulêre siektes, tipe-2 diabetes mellitus, lewervervetting sindroom, ortopediese komplikasies en sekere soorte kanker. Snoepies in skole voorsien meestal ongesonde items met ‘n hoë energie, vet- en/of suikerinhoud en wat laag is in vitamiene, minerale en dieetvesel. Die beskikbaarheid van ongesonde items in snoepies verhoed dat leerders gesonde voelselkeuses uitoefen, omdat kinders geneig is om voorkeur aan ongesonde kos te gee as hulle 'n keuse gebied word. Benewens die ongesonde items wat snoepies aanbied, neem leerders boonop ongesonde kos in hul kosblikke skooltoe. Die doel van die studie was om by 'n Afrikaans dubbelmedium laerskool in Bloemfontein die invloed van ‘n voedingkundig-gereguleerde snoepie op leerders se persepsies, houdings en gedrag teenoor gesonde eetgewoontes te ondersoek en te vergelyk met leerders in 'n skool met 'n konvensionele snoepie. Metodes: In ‘n deursnit-opname met ‘n analitiese komponent, het graad 2 tot 7 leerders in ‘n skool met ‘n voedingkundig-gereguleerde snoepie (n=116) en ‘n skool met ‘n konvensionele snoepie (n=141), ‘n vraelys ingevul. Ses leerders in elke graad in elk van die skole het ook aan fokusgroepbesprekings deelgeneem. Vrae het oor die inhoud van kosblikke, asook persepsies, houding en gedrag teenoor die snoepie en gesonde eetgewoontes, gehandel. Voedingsinligting rakende die items wat in elk van die skole se snoepies verkoop word, is ook ingesamel. Resultate: Die kosblikke van leerders in ‘n skool met ‘n voedingkundig-gereguleerde snoepie het statisties beduidend (p<0.05) meer gesonde items bevat (vrugte, water en muffins), maar ook beduidend meer ongesonde items (lekkergoed en aartappelskyfies). Voedsel-items wat in die voedingkundig-gereguleerde snoepie beskikbaar was, het omtrent die helfte minder energie bevat as voedsel-items wat in die konvensionele snoepie beskikbaar was. Leerders in ‘n skool met ‘n voedingkundig-gereguleerde snoepie het beduidend (p<0.05) meer van sekere groente en vrugte gehou as leerders in ‘n skool met ‘n konvensionele snoepie. Statisties beduidende (p<0.05) verskille tussen verskillende grade en die houding van verskillende geslagte dui daarop dat graad 2 leerders in albei skole minder positief gevoel het oor sekere groente en vrugte as ouer leerders, terwyl meisies in albei skole ‘n meer positiewe houding teenoor sekere groente en vrugte getoon het as seuns. Jonger leerders het ‘n meer positiewe houding teenoor hulle voedingkundig-gereguleerde snoepie getoon as ouer leerders. In albei skole het leerders soortgelyke persepsies rondom hul onderskeie skole se snoepies en gesonde eetgewoontes openbaar. Gevolgtrekking: Die hipotese dat leerders in ‘n skool met ‘n voedingkundig-gereguleerde snoepie positiewe persepsies, houding en gedrag teenoor gesonde eetgewoontes toon is nie aanvaar nie. Die beskikbaarheid van gesonder items in ‘n skoolsnoepie het 'n positiewe invloed op sekere eetgewoontes en houdings van die leerders, maar die potensiële waarde daarvan om die tipes voedsel wat by skole te koop aangebied word te reguleer mag egter teengewerk word deur kosblikke se inhoud asook sekere vaste eetpatrone, persepsies van leerders en vorige blootstelling aan ‘n konvensionele snoepie. ‘n Veelvoudige benadering soos die konsep van ‘n Gesondheidbevorderingskool word aanbeveel.

Resent research has demonstrated that age does not play as big a part in second language (L2) acquisition as was previously thought. However, L2 acquisition is markedly affected by: (i) the amount of L2 in a pupil’s daily life, (ii) how well teachers are trained in teaching a new language to young learners and (iii) how many hours are given to the subject each week. In Swedish schools there is great variation around when and how English is taught. In order to ensure future equality in L2 teaching we need to find out why this variation exists. One important step towards doing this is to obtain primary school teachers’ views on teaching English. Using a questionnaire, I gathered views from Swedish primary school teachers regarding their own English teaching skills and when they believe English should be taught. The findings show that views on when to start teaching English differ markedly among teachers, varying from year 1 to year 3, as does any relevant guidance from schools/municipalities. It is also apparent that many teachers, 65% of the respondents in this study to be exact, have not had English as an obligatory part of their teacher training. The findings offer a valuable insight into potential underlying reasons for the variability that exists in L2 teaching.
Forskningen under senare år har visat att ålder inte har en lika stor roll i andraspråksinlärning som man tidigare trott. Dock påverkas andraspråksinlärning märkbart av: (i) hur mycket av ett andraspråk som finns med i elevernas dagliga liv, (ii) hur utbildade lärare är inom området för att lära ut ett nytt språk till yngre elever och (iii) hur många timmar som ges till ämnet varje vecka. En stor variation finns inom den svenska skolan när det gäller när och hur engelska lärs ut. För att försäkra oss om en likvärdig utbildning i framtiden så måste vi undersöka varför det är en sådan variation. En viktig del i detta är att få reda på lågstadielärarnas egna åsikter om att lära ut engelska. Genom ett frågeformulär samlade jag in åsikter från svenska lågstadielärare när det gäller deras lärarkunskaper inom engelska och när de anser att engelska bör läras ut. Resultaten visar att det finns delade åsikter inom lärarprofessionen angående när undervisning i engelska bör påbörjas, allt från åk 1 till åk 3, detta gäller även vägledning från skolor/kommuner. Det är också tydligt att många lärare, 65% av respondenterna i denna studie för att vara mer precis, inte har haft engelska som en obligatorisk del av sin lärarutbildning. Resultaten ger en viktig inblick i eventuella bakomliggande orsaker till variabiliteten som existerar när det gäller andraspråksundervisning.

Si l’école française veut faire réussir tous les élèves qu’ils soient issus de milieux favorisés ou défavorisés, elle se doit de leur donner le plus tôt possible des outils intellectuels permettant de se comprendre, de comprendre les autres et le monde au travers de la construction des savoirs scolaires. L’objectif majeur poursuivi par cette thèse est de construire des pistes afin d’arrêter la construction inexorable des inégalités scolaires et des différences d’efficience liés à l’accès aux savoirs scolaires. Cette recherche est construite sur l’hypothèse que s’il est possible d’identifier des variables, des composantes dans l’activité enseignante qui peuvent dans certaines situations avoir un impact plus important sur les progrès et les performances des élèves en compréhension de textes lus ou entendus que d’autres, qui peuvent être à même d’expliquer la variabilité des acquisitions des élèves, cela signifie que l’école pourrait être en capacité de lutter contre les disparités sociales et culturelles. Elle ne serait plus un simple révélateur mais jouerait un rôle dans l’amélioration des acquisitions des élèves. Faire réussir tous les élèves en compréhension de textes lus ou entendus quel que soit leur milieu d’origine serait donc possible.Des variables qualitatives et quantitatives voient donc le jour.Les liens entre les variables quantitatives sont étudiés à l’aide du coefficient de corrélation de Spearman lequel mesure la force de la corrélation et indique également son sens. Et les liens entre une variable qualitative et une variable quantitative sont étudiés par un test de Student ou un test non paramétrique de Wilcoxon.L’ensemble des résultats met en évidence certaines variables à même de jouer un effet significatif dans les progrès des élèves. Ce sont :- les moments de temps d’enseignement de la lecture accompagnée portant sur les habiletés de compréhension et l’étude de la langue,- les questions ouvertes, sans raté lexical, syntaxique et d’élocution portant sur l’élucidation du sens et l’étude de la langue- et le traitement de l’erreur.Ce travail statistique révèle, aussi, l’existence de certaines combinaisons mieux à même d’exercer un effet significatif sur les progrès des élèves et d’identifier des pratiques qui seraient caractéristiques d’options didactiques-clefs. Le traitement de l’erreur constitue l’un des élèments fondamentaux du processus d’apprentissage. Elle en est une composante structurelle, la variable clé à même d’expliquer les configurations didactiques dans la progression relative des performances des élèves en compréhension de textes lus ou entendus.La doxa selon laquelle il existerait une fatalité héréditaire aux inégalités sociales et culturelles, peut être à nouveau dénoncée au regard de ces résultats
If french schools want all students to succeed, whether they come from advantaged or disadvantaged backgrounds, they must give them as early as possible the intellectual tools to understand themselves, others and the world through the construction of this school knowledge. The main objective is to identify ways to stop the inexorable construction of school inequalities and differences in efficiency linked to access to school knowledge.This research is based on the hypothesis that if it is possible to identify variables, components in the teaching activity that can in certain situations have a greater impact on student's progress and performance in reading and listening comprehension than others, which may be able to explain the variability in student's acquisition, it means that the school could be able to fight against social and cultural disparities. It would no longer be a mere revealing factor but would play a role in improving student learning. It would therefore be possible to make all students succeed in reading or hearing texts regardless of their background.Qualitative and quantitative variables are emerging.The links between the quantitative variables are studied using the Spearman correlation coefficient which measures the strength of the correlation and also indicates its direction. And the links between a qualitative and a quantitative variable are studied by a Student test or a non-parametric Wilcoxon test.All the results presented by this doctoral research highlight certain variables capable of having a significant effect on pupils' progress. These are :- the amount of time spent teaching on comprehension skills and language study,- open-ended, lexical, syntactic and elocution questions for elucidation of meaning and study of language- and treatment of error.This statistical work then reveals the existence of certain combinations that are better able to have a significant effect on student progress and to identify practices that would be characteristic of key didactic options.The treatment of error is one of the fundamental elements of the learning process. It is a structural component, the key variable that can explain the didactic configurations in the relative progression of students' performance in understanding texts read or heard.The doxa, according to which there is a hereditary fatality to social and cultural inequalities, can again be denounced in the light of these results

L'etude des formations volcaniques associees au bassin stephanien de la chapelle-sous-dun (charollais) permet de preciser les relations entre phenomenes magmatiques et post-magmatiques d'une part, et les indices ou anomalies geochimiques (u. F. ) d'autre part. Les formations volcaniques font partie d'un ensemble plutono-volcanique complexe. La localisation de ces phenomenes est guidee par le contexte structural et, en particulier, l'existence de zones de type pull-apart dans un contexte compressif generalise. Les phenomenes post-magmatiques, en particulier la devitrification des roches volcaniques, sont fonction des natures lithologiques initiales. Les phenomenes d'evolution post-magmatique de la pile volcanique ont amene une liberation de l'u et son piegeage dans les biotites chloritisees, elles aussi associees aux processus secondaires. Toutefois, le mecanisme du piegeage de l'u n'a pu etre precise. Des phenomenes limites de remobilisations hydrothermales ou supergenes peuvent etre a l'origine des indices reconnus dans le stephanien

Une prospection geologique systematique de ces terrains a conduit a la reconnaissance de quatre principaux types de mineralisations dans le socle, le devonien inferieur et le cretace : 1 - une mineralisation stratiforme a zn-pb-ba-f de type sedimentaire - exhalatif omnipresente au sommet de la barre calcaire emsienne (devonien inferieur). 2 - de nombreux filons de types b. P. G. C. A gangue de siderite avec, pour certains, presence importante de barytine ou de fluorine ; ces filons correspondent a une phase de mineralisation tardi-hercynienne, probablement en liaison avec une phase tectonique compressive impliquant un contexte decrochant a composante cisaillante senestre, evoluant progressivement vers une distension nord-sud. 3 - des amas metasomatiques a mg-fe dans la barre calcaire emsienne, pouvant representer le sommet du systeme hydrothermal responsable des filons tardi-hercyniens du socle. 4 - la dissemination de galene dans les calcaires du santonien et de petits amas decimetriques de barytine secants sur la dolomie greseuse du cenomanien ; ces indices traduisent la remobilisation de filons tardi-hercyniens principalement d'apres l'identite des compositions isotopiques du plomb.

La present tesi doctoral s’ha centrat en el repte d’aconseguir, mitjançant Fabricació Additiva (FA), models per a assaig quirúrgic, sota la premissa que els equips per fer-los haurien de ser accessibles a l’àmbit hospitalari. L’objectiu és facilitar l’extensió de l’ús dels prototips com a eina de preparació d’operacions quirúrgiques, transformant la pràctica mèdica actual de la mateixa manera que en el seu moment ho van fer tecnologies com les que van facilitar l’ús de radiografies. El motiu d’utilitzar FA, en lloc de tecnologies més tradicionals, és la seva capacitat de materialitzar de forma directa les dades digitals obtingudes de l’anatomia del pacient mitjançant sistemes d’escanejat tridimensional, fent possible l’obtenció de models personalitzats. Els resultats es centren en la generació de nou coneixement sobre com aconseguir equipaments d’impressió 3D multimaterials accessibles que permetin l’obtenció de models mimètics respecte als teixits vius. Per facilitar aquesta buscada extensió de la tecnologia, s’ha focalitzat en les tecnologies de codi obert com la Fabricació per Filament Fos (FFF) i similars basades en líquids catalitzables. La recerca s’alinea dins l’activitat de desenvolupament de la FA al CIM UPC, i en aquest àmbit concret amb la col·laboració amb l’Hospital Sant Joan de Déu de Barcelona (HSJD). El primer bloc de la tesi inclou la descripció de l’estat de l’art, detallant les tecnologies existents i la seva aplicació a l’entorn mèdic. S’han establert per primer cop unes bases de caracterització dels teixits vius -sobretot tous- per donar suport a la selecció de materials que els puguin mimetitzar en un procés de FA, a efectes de millorar l’experiència d’assaig dels cirurgians. El caràcter rígid dels materials majoritàriament usats en impressió 3D els fa poc útils per simular tumors i altres referències anatòmiques. De forma successiva, es tracten paràmetres com la densitat, la viscoelasticitat, la caracterització dels materials tous a la indústria, l’estudi del mòdul elàstic de teixits tous i vasos, la duresa d’aquests, i requeriments com l’esterilització dels models. El segon bloc comença explorant la impressió 3D mitjançant FFF. Es classifiquen les variants del procés des del punt de vista de la multimaterialitat, essencial per fer models d’assaig quirúrgic, diferenciant entre solucions multibroquet i de barreja al capçal. S’ha inclòs l’estudi de materials (filaments i líquids) que serien més útils per mimetitzar teixits tous. Es constata com en els líquids, en comparació amb els filaments, la complexitat del treball en processos de FA és més elevada, i es determinen formes d’imprimir materials molt tous. Per acabar, s’exposen sis casos reals de col·laboració amb l’HJSD, una selecció d’aquells en els que el doctorand ha intervingut en els darrers anys. L’origen es troba en la dificultat de l’abordatge d’operacions de resecció de tumors infantils com el neuroblastoma, i a la iniciativa del Dr. Lucas Krauel. Finalment, el Bloc 3 té per objecte explorar nombrosos conceptes (fins a 8), activitat completada al llarg dels darrers cinc anys amb el suport dels mitjans del CIM UPC i de l’activitat associada a treballs finals d’estudis d’estudiants de la UPC, arribant-se a materialitzar equipaments experimentals per validar-los. La recerca ampla i sistemàtica al respecte fa que s’estigui més a prop de disposar d’una solució d’impressió 3D multimaterial de sobretaula. Es determina que la millor via de progrés és la de disposar d’una pluralitat de capçals independents a fi de capacitar la impressora 3D per integrar diversos conceptes estudiats, materialitzant-se una possible solució. Cloent la tesi, es planteja com seria un equipament d’impressió 3D per a models d’assaig quirúrgic, a fi de servir de base per a futurs desenvolupaments.
La presente tesis doctoral se ha centrado en el reto de conseguir, mediante Fabricación Aditiva (FA), modelos para ensayo quirúrgico, bajo la premisa que los equipos para obtenerlos tendrían que ser accesibles al ámbito hospitalario. El objetivo es facilitar la extensión del uso de modelos como herramienta de preparación de operaciones quirúrgicas, transformando la práctica médica actual de la misma manera que, en su momento, lo hicieron tecnologías como las que facilitaron el uso de radiografías. El motivo de utilizar FA, en lugar de tecnologías más tradicionales, es su capacidad de materializar de forma directa los datos digitales obtenidos de la anatomía del paciente mediante sistemas de escaneado tridimensional, haciendo posible la obtención de modelos personalizados. Los resultados se centran en la generación de nuevo conocimiento para conseguir equipamientos de impresión 3D multimateriales accesibles que permitan la obtención de modelos miméticos respecto a los tejidos vivos. Para facilitar la buscada extensión de la tecnología, se ha focalizado en las tecnologías de código abierto como la Fabricación por Hilo Fundido (FFF) y similares basadas en líquidos catalizables. Esta investigación se alinea dentro de la actividad de desarrollo de la FA en el CIM UPC, y en este ámbito concreto con la colaboración con el Hospital Sant Joan de Déu de Barcelona (HSJD). El primer bloque de la tesis incluye la descripción del estado del arte, detallando las tecnologías existentes y su aplicación al entorno médico. Se han establecido por primera vez unas bases de caracterización de los tejidos vivos – principalmente blandos – para dar apoyo a la selección de materiales que los puedan mimetizar en un proceso de FA, a efectos de mejorar la experiencia de ensayo de los cirujanos. El carácter rígido de los materiales mayoritariamente usados en impresión 3D los hace poco útiles para simular tumores y otras referencias anatómicas. De forma sucesiva, se tratan parámetros como la densidad, la viscoelasticidad, la caracterización de materiales blandos en la industria, el estudio del módulo elástico de tejidos blandos y vasos, la dureza de los mismos, y requerimientos como la esterilización de los modelos. El segundo bloque empieza explorando la impresión 3D mediante FFF. Se clasifican las variantes del proceso desde el punto de vista de la multimaterialidad, esencial para hacer modelos de ensayo quirúrgico, diferenciando entre soluciones multiboquilla y de mezcla en el cabezal. Se ha incluido el estudio de materiales (filamentos y líquidos) que serían más útiles para mimetizar tejidos blandos. Se constata como en los líquidos, en comparación con los filamentos, la complejidad del trabajo en procesos de FA es más elevada, y se determinan formas de imprimir materiales muy blandos. Para acabar, se exponen seis casos reales de colaboración con el HJSD, una selección de aquellos en los que el doctorando ha intervenido en los últimos años. El origen se encuentra en la dificultad del abordaje de operaciones de resección de tumores infantiles como el neuroblastoma, y en la iniciativa del Dr. Lucas Krauel. Finalmente, el Bloque 3 desarrolla numerosos conceptos (hasta 8), actividad completada a lo largo de los últimos cinco años con el apoyo de los medios del CIM UPC y de la actividad asociada a trabajos finales de estudios de estudiantes de la UPC, llegándose a materializar equipamientos experimentales para validarlos. La investigación amplia y sistemática al respecto hace que se esté más cerca de disponer de una solución de impresión 3D multimaterial de sobremesa. Se determina que la mejor vía de progreso es la de disponer de una pluralidad de cabezales independientes, a fin de capacitar la impresora 3D para integrar diversos conceptos estudiados, materializándose una posible solución. Para cerrar la tesis, se plantea cómo sería un equipamiento de impresión 3D para modelos de ensayo quirúrgico, a fin de servir de base para futuros desarrollos.

碩士
臺北市立教育大學
自然科學系碩士班
99
The purpose of this study was to explore the propriety of changing the photosynthesis learning stage of Grade 1-9 C.G. and the feasibility of designing photosynthesis concepts to merge the current “aquatic unit” of the fourth grade in Science and Technology. Firstly, the documentary analysis was used to compare the difference of primary photosynthesis curriculum among United States, Japan and Taiwan. Secondly, the researcher developed two questionnaires: EPCQ and TPCQ. The EPCQ was to investigate the opinions of 17 professors of Education Universities, including scientific scholars, subject experts and curriculum experts, etc. The TPCQ was to investigate the perspective of 51 primary teachers about Grade 1-9 C.G. of photosynthesis curriculum. The researcher designed an instruction unit that the “aquatic unit” of the fourth grade curriculum which merged with the photosynthesis concepts, and two questionnaires, G4PCQ and G4FQ. The experimental method was one group pretest-posttest design to exam 61 the fourth graders’ learning results on the photosynthesis unit. Findings as follows: The scientific scholars agreed: (1) Photosynthesis curriculum should be added to the primary stage of G1-9 C.G. (2) For primary stage, teaching the phenomenon of photosynthesis is appropriate. (3) Disagreeing the phenomenon of photosynthesis were moved to junior stage. The primary teachers approved: (1) For primary students, understanding of photosynthesis is one of the important scientific literacy in this era. (2) Teaching the phenomenon of photosynthesis on primary stage will enable students to understand about photosynthesis basically. (3) According to students’ cognitions, spiral photosynthesis curriculum design should be shown up appropriatly in the primary and junior stages. The average scores of pre and post test of G4PCQ had significant differences. Except for “the role of sunshine", “the gas raw material of photosynthesis", “the gas product of photosynthesis", “plants need water", and “respiration and photosynthesis", these average scores of post-test were higher than pre-test ones. The average scores of pre and post test of five dimensions also reached significant differences. Before teaching the photosynthesis unit, “the role of the sunshine” was the best performance among other dimensions. After teaching, “the gas product of photosynthesis” made great progress. The results of G4FQ: (1) almost 95% respondents agreed that understand "photosynthesis" was helpful for them. (2) 98.3% respondents consented “Energy Saving and Carbon Reduction” were very popular and important issues at this time. (3) almost 90% respondents considered that photosynthesis curriculum was very interesting. According to the findings, the researcher suggested that the phenomenon of photosynthesis may be taught during the primary stage of G1-9 C.G. in the future. The relationship of the photosynthesis conceps of “Oxygen” and “Sun” may be learmed on the second stage of the primary school. The relationship of “Carbon Dioxide” and “Oxygen”could be taughted on the third stage of the primary school.

M.Ed. (Mathematics in Education)
Primary school learners need to extend their knowledge of numbers to include common fractions. Common fraction concepts are important but learners find it more complicated and difficult to understand than whole numbers, they experience it as particularly challenging. Fraction consists of sub constructs which is adding to the complexity of fractions. The aim of this study was twofold, firstly, to identify the conceptual and procedural knowledge about common fractions that learners need to acquire from grade four to seven to enable them to be able to do calculations with fractions. The second aim was identifying effective teaching strategies to enhance learners’ conceptual and procedural knowledge about common fractions. Primary school learners are mainly in the concrete operational stage of development according to Piaget’s stages of cognitive development. Although the learner can reason, the ability to reason is based on tangible objects and direct experiences. The obstacles that learners encounter in developing deep understanding of fractions can be due to the nature of fractions or due to the instructional approaches employed by the teachers. Learners are able to understand at a concrete level, their reasoning is consistent with respect to real objects. To enable learners to develop meaning and understanding of fractions, learners should be provided with many experiences in partitioning quantities into equal parts. Teachers must ensure learners make the connections between the concrete models, manipulatives and pictures that are equally divided. Learners need to be able to represent numbers using words, models, diagrams and symbols and be able to make the connections between the representations. From a constructivist view learners construct their own knowledge and the learning of subject matter is the product of an interaction between what they are taught and the knowledge they bring to the learning situation.

Autosomal recessive primary microcephaly (MCPH) is a congenital neurodevelopmental disorder characterised by a reduced occipital-frontal head circumference (OFC) of less than -3 SDs below the population mean for age and sex. It is a genetically heterogeneous disorder caused by mutations in one of the following 10 MCPH genes: MCPH1 (microcephalin 1), WDR62 (WD repeat domain 62), CDK5RAP2 (cyclin-dependent kinase 5 regulatory associated protein 2), CASC5 (cancer susceptibility candidate 5), CEP152 (centrosomal protein 152 kDa), ASPM (asp [abnormal spindle] homolog, microcephaly associated [Drosophila]), CENPJ (centromeric protein J), STIL (SCL/TAL1-interrupting locus), CEP135 (centrosomal protein 135 kDa) and CEP63 (centrosomal protein 135 kDa). The MCPH1 (microcephalin 1) gene is located on chromosome 8p23.1. Microsatellite analysis has previously shown LOH at the markers D8S518 and D8S277 flanking the MCPH1 locus in 1/21 oral tumors. Furthermore, LOH at the markers D8S1742 and D8S277 flanking the MCPH1 locus has also been observed in 2/32 hepatocellular carcinomas. MCPH1 has been found to be mutated in breast and endometrial cancers. Additionally, it was found to be downregulated at the transcript level in 19/30 ovarian cancer tissues and the protein level in 93/319 breast cancer tissues. Decreased MCPH1 protein levels are associated with triple negative breast cancers and a lower transcript level of MCPH1 correlates with lesser time for metastasis to occur in breast cancer patients. Interestingly, MCPH1 knockout mice in a null TP53 background show susceptibility to cancer.So far, studies have indicated that MCPH1 is a DNA repair protein. MCPH1 is required for the formation of DNA repair foci, chromatin relaxation, HR and NHEJ. It regulates G1/S and G2/M cell cycle checkpoints. Also, depletion of MCPH1 leads to genomic instability and centrosome amplification. Hence, the defect in the function of MCPH1 can lead to plethora of anomalies including cancer. Based on these observations, we hypothesized that MCPH1 may also function as a tumor suppressor (TS) gene, in addition to its role in the brain development. The purpose of this study was to test if MCPH1 also functions as a TS gene using different approaches in OSCC (oral squamous cell carcinoma). OSCC is the sixth most common type of cancer. It includes the cancer of the lips, anterior 2/3rd of the tongue, buccal mucosa, floor of the mouth, retromolar trigone and gingiva. Despite the advances in the treatment of oral cancer, the five-yr survival rate has not increased. Hence, the effective treatment of OSCC requires the identification of molecular targets to design appropriate therapeutic strategies. LOH, mutations and promoter methylation in tumors are the hallmarks of TS genes. In order to ascertain the TS roles of MCPH1, we carried out LOH analysis in 81 matched blood/normal and tumor oral tissues using D8S1819, D8S277 and D8S1798 markers flanking the MCPH1 locus. The results showed LOH at one or more markers in 14/71 (19.72%) informative samples across the tumor stages from T1 to T4. The entire coding region and the exon-intron junctions of the MCPH1 gene were sequenced for mutations in 15 OSCC samples and 5 cancer cell lines (viz., A549, HeLa, KB, SCC084 and SCC131). In total, three mutations namely c.1561G>T(p.Glu521X), c.321delA(p.Lys107fsX39) and c.1402delA(p.Thr468fsX32) were identified. The expression of MCPH1 was analysed at both the transcript and protein levels by real-time quantitative RT-PCR and immunohistochemistry, respectively, in OSCC samples. MCPH1 was downregulated in 51.22% (21/41) of OSCC samples at the transcript level. The MCPH1 protein was downregulated in 76% (19/25) of the OSCC samples. In order to elucidate if the MCPH1 promoter was methylated in OSCC tissues, we retrieved the MCPH1 promoter from the database TRED (Transcriptional Regulatory Element Database). The promoter was analysed for the presence of CpG islands using the CpG Plot/CpG Report program. Two CpG islands (CpGI and CpGII) were identified within the MCPH1 promoter. Both the CpG islands were analysed for methylation in 40 OSCC samples by COBRA (Combined Bisulfite Restriction Analysis). CpGI showed no methylation in 40 OSCC samples. However, CpGII showed methylation in 4/40 (10%) OSCC samples and the methylation was absent in their corresponding normal oral tissues. To analyse the methylation of the MCPH1 promoter in cancer cell lines, HeLa, KB, SCC084 and SCC131 cells were treated with 5’-2-deoxy azacytidine (AZA), a methyltrasferase inhibitor. HeLa and KB cells did not show any change in the MCPH1 transcript level after the AZA treatment. However, SCC084 and SCC131 cells showed upregulation of MCPH1 after the treatment, suggesting methylation of the MCPH1 promoter. To validate these observations, we examined the methylation status of both the CpG islands in these cell lines. We found methylation of CpGII only in SCC084 cells. HeLa, KB and SCC131 cells showed no methylation of CpGI and CpGII. The results obtained by COBRA in these cell lines were further confirmed by bisulfite sequencing of CpGI and CpGII islands. Further, the upregulation of MCPH1 after azacytidine treatment in SCC131 cells can be attributed to a promoter independent mechanism or due to methylation of the CpG sites not examined by us. To elucidate the biological effects of MCPH1 in a cancer cell line, we generated stable clones overexpressing MCPH1 in KB cells. The results showed that MCPH1 overexpression decreased cellular proliferation, cell invasion, anchorage-independent growth in soft-agar and tumor growth in nude mice. Further, MCPH1 overexpression lead to apoptosis. A low frequency of LOH, mutations and promoter methylation suggested that they might not be the major mechanisms of downregulation of MCPH1 in OSCC. We then speculated that MCPH1 could be regulated by miRNAs. We therefore used five miRNA target prediction softwares to identify miRNAs targeting MCPH1. The programs identified two binding sites for miR-27a within the 5.4 kb region of the 3’-UTR of MCPH1. The luciferase assay showed that both the seed regions of MCPH1 were binding to miR-27a. In addition, transient transfection of the premiR-27a construct in KB cells decreased the protein level of MCPH1. Additionally, in a small panel of 10 OSCC samples, there was a negative correlation between the levels of miR-27a and MCPH1. To the best of our knowledge, this is the first report showing any miRNA regulating the MCPH1 gene. It is important to note that tumor suppressors can serve as potential biomarkers with prognostic value. Hence, we analysed the correlation of the expression levels of MCPH1 with clinico-pathological parameters such as TNM, gender, age and site of the cancer by Fischer’s exact test. No statistical correlation was observed between the transcript or protein levels with any of the clinico-pathological parameters. In summary, the results of the present study have suggested that the primary microcephaly gene MCPH1 shows several hallmarks of TS genes and functions as a tumor suppressor in OSCC, in addition to its role in brain development. We have for the first time shown that miR-27a targets MCPH1 and regulates its level. It is interesting to note that none of the other 10 MCPH genes have been shown to be regulated by any miRNA yet. Our study will be useful in designing novel therapeutic methods for the treatment of OSCC either by overexpression of MCPH1 or reducing the level of miR-27a by an antagomir.

碩士
國立體育學院
運動科學研究所
92
In the nowadays world the pool fighting method is extremely important. The purpose of this research is to discuss the relationship among primary school grade five male students’ forehand-drive cognition, drive skill and number of shots. Meanwhile, this research attempts to establish analysis method of forehand-drive skills, cognition test systems, and skill observation tables. This research adopts random sampling method, and 90 male students of primary school have been chosen as sampling frame. Pearson correlation analysis(α=.05) has been applied to test the relationship among variables.As a consequence, this research has significant findings summarized as below: 1. Figure of Table tennis forehand-drive skill analysis has been established. Table of forehand-drive skill observation has been established.3. Forehand-drive cognition test system has been established. 2. There is a significant relationship between forehand-drive skill and number of shots.3. There is a significant relationship between forehand-drive cognition and number of shots.There is a significant relationship between forehand-drive cognition and forehand-drive skill.

碩士
大葉大學
造形藝術學系碩士在職專班
96
ABSTRACT The objective of this paper is to discuss the relation of study motivation and satisfaction for elementary students in ChagHua district, especially for students in grades 5 and 6. Total samples are 630. The papers used referenced are “Art and the chart of personal motivation” and “Art and the chart of satisfaction”. All data was collected through questionnaires and personal interviews. Sample tests were also used with SPSS Windows 10.0 Chinese version. Analysis of single factor and Fisher multiple data was compared. The results are as follows: 1st: Based on the analysis of statistical variation in population, there are large variances for the study motivation of elementary students in ChangHua county within the categories of “Gender”, “Grade”, “The behaviour of the art class” and “Previous attendance of art class”. 2nd: Based on the analysis of statistical variation in population, there are large variances for the study satisfaction of elementary students in ChangHua county within the categories of “Gender”, “Grade”, “The behaviour of the art class” and “Previous attendance of art class”. 3rd: Based on the analysis of statistical variation in population, there are large variances for the study motivation in artistic areas for elementary students in ChangHua county, especially within the categories of “Teacher's gender”, “Teacher's seniority” and “The subject major for the teacher being art”. 4th: Based of the analysis of statistical variation in population, there are large variances for the study satisfaction in artistic areas for elementary students in ChangHua county, especially within the categories of “Teacher's gender”, “Teacher's seniority” and “The subject major for the teaching being art”. Key words: Art and Culture for Elementary schools; Learning Motivation; Learning Satisfaction

Thesis (M. Tech. Dept. of Hospitality, Tourism and PR Management)--Vaal University of Technology, 2009.
Background: Approximately 45% of South Africans are overweight, including 20% of children under six years of age. Snack foods are now targeted in the food industry, globally, as an obesity prevention initiative, focusing on children to ensure the adoption of a healthy lifestyle from an early age. Objectives: The purpose of this study was to determine the nutritional status and snack consumption patterns of children (n=290) 9 to 13 years old in the Vaal Region at two purposively selected primary schools in order to develop a healthy snack food item that will address obesity in children from a very young age. Methods: A baseline survey included a pre-tested questionnaire, administered by trained fieldworkers to determine snack food consumption patterns. Anthropometric measurements included weight and height. A snack food item was developed to meet certain criteria identified from the literature and baseline survey. The methods included: snack food development and preparation, chemical analyses to determine actual content, microbiological tests to determine shelf life and sensory analyses to determine acceptability. Study design: Cross-sectional analytical study. Data analyses: Data of the questionnnaires were captured and analysed for descriptive statistics (frequencies, means and standard deviations). The anthropometric data were captured and analysed using the World Health Organisation (WHO) standards for 2007. Results: The results showed that the children in the sample knew the meaning of healthy snacks, although the majority (66.8%) consumed unhealthy snacks, especially from school tuck shops. The top ten snack foods most commonly consumed daily were: coffee (48.3%), tea (46.1%), crispy chips (39.1%), fruit juice (38.0%), chicken (35.1%), fried potato chips (33.6%), carbonated drinks (26.9%), biscuits (26.2%), toffees (26.2%) and yoghurt (25.8%). The majority (56.8%) of the respondents indicated that they receive between R2 and R5 per week for tuck shop money, besides their monthly pocket money (64.6%). Most of the respondents (45.4%) spend their pocket money on snack food items and these are mainly consumed while watching television (36.9%) and when bored (29.5%). The anthropometric results indicated that 11.7% of the group were underweight, 12.1% of the group were stunted; in addition 20% were at risk of underweight, and 23.4% at risk of being stunted. A significantly higher percentage of girls (16.81) were stunted compared with the boys (5.0%). Also 7.6% of the group were overweight. More girls were overweight compared with boys. A snack food item was developed to address obesity in this region. The criteria met were that it was affordable, at cost of R0.55 per 30g portion, was low in fat and had high-density nutritional value, with at least 20% of the DRI for protein and iron, had a shelf life of 28 days and was generally acceptable to the majority of the respondents. Conclusion and recommendations: This study showed that obesity is becoming a problem amongst children in the Vaal Region. Although primary school children knew healthy snack foods, their behaviour indicated a large consumption of unhealthy snack foods. A low-fat, low-energy, low-cost and acceptable snack food item was successfully developed to address the obesity problem in the region. Further research is recommended where this snack food item is implemented in an intervention study to measure its impact on the nutritional status of obese primary school children.
National Research Foundation