Gotowe bibliografie tematyczne / Premature ageing / Artykuły w czasopismach

Artykuły w czasopismach na temat „Premature ageing”

Kliknij ten link, aby zobaczyć inne rodzaje publikacji na ten temat: Premature ageing.
Autor: Grafiati
Data publikacji: 20 lipca 2024

Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych

Wybierz rodzaj źródła:

Sprawdź 50 najlepszych artykułów w czasopismach naukowych na temat „Premature ageing”.

Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.

Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.

Przeglądaj artykuły w czasopismach z różnych dziedzin i twórz odpowiednie bibliografie.

1

Villanueva, M. Teresa. "Slowing premature ageing". Nature Reviews Cancer 15, nr 5 (24.04.2015): 259. http://dx.doi.org/10.1038/nrc3956.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
2

Joss, Nicola, J. Michael Boulton‐Jones i Ian More. "Premature ageing and glomerulonephritis". Nephrology Dialysis Transplantation 16, nr 3 (1.03.2001): 615–18. http://dx.doi.org/10.1093/ndt/16.3.615.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
3

Smith, Michael. "Premature Ageing: History and Biology". Journal of the Royal Society of Medicine 87, nr 7 (lipiec 1994): 425–27. http://dx.doi.org/10.1177/014107689408700720.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
4

Biesalski, H. K., M. Berneburg, T. Grune, M. Kerscher, J. Krutmann, W. Raab, J. Reimann, T. Reuther, L. Robert i T. Schwarz. "Oxidative and premature skin ageing". Experimental Dermatology 12, s3 (grudzień 2003): 3–15. http://dx.doi.org/10.1111/j.0906-6705.2003.00148.x.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
5

Dokal, Inderjeet. "A disease of premature ageing". Lancet 358 (grudzień 2001): S27. http://dx.doi.org/10.1016/s0140-6736(01)07040-4.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
6

Silverstein, Janet H. "Does diabetes cause premature AGEing?" Journal of Pediatrics 172 (maj 2016): 1–4. http://dx.doi.org/10.1016/j.jpeds.2016.03.011.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
7

Testori, Alessandro. "Short telomere syndromes, premature ageing syndromes, and biological ageing". Hong Kong Medical Journal 26, nr 1 (22.01.2020): 76–77. http://dx.doi.org/10.12809/hkmj187782.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
8

Lehmann, Alan. "Ageing: Repair and Transcription Keep Us from Premature Ageing". Current Biology 12, nr 16 (sierpień 2002): R550—R551. http://dx.doi.org/10.1016/s0960-9822(02)01050-3.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
9

DYER, CHRISTOPHER A. E., i ALAN J. SINCLAIR. "The premature ageing syndromes: insights into the ageing process". Age and Ageing 27, nr 1 (1998): 73–80. http://dx.doi.org/10.1093/ageing/27.1.73.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
10

Swanton, Alexander, i Tim Child. "Reproduction and ovarian ageing". British Menopause Society Journal 11, nr 4 (1.12.2005): 126–31. http://dx.doi.org/10.1258/136218005775544200.

Pełny tekst źródła
Streszczenie:
Female fertility rates are inherently linked to a woman's age, which is in turn related to ovarian function. Reproductive potential declines gradually until 37–38 years of age, from when the rate of decline hastens. Approximately 1% of women suffer from premature ovarian ageing, and many may not have completed their families. This paper reviews the physiology and fertility consequences of ovarian ageing, premature ovarian failure, measures of ovarian reserve and methods of fertility preservation.
Style APA, Harvard, Vancouver, ISO itp.
11

Bhimani, Bhagyashri, Ankita Viroja i D. V. Patel. "PREMATURE AGEING (AKALAJA JARA): AYURVEDIC VIEW". Journal of Biological & Scientific Opinion 4, nr 1 (16.03.2016): 26–28. http://dx.doi.org/10.7897/2321-6328.0417.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
12

Coppede, Fabio. "Mutations Involved in Premature-Ageing Syndromes". Application of Clinical Genetics Volume 14 (czerwiec 2021): 279–95. http://dx.doi.org/10.2147/tacg.s273525.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
13

Kooman, Jeroen P., Peter Kotanko, Annemie M. W. J. Schols, Paul G. Shiels i Peter Stenvinkel. "Chronic kidney disease and premature ageing". Nature Reviews Nephrology 10, nr 12 (7.10.2014): 732–42. http://dx.doi.org/10.1038/nrneph.2014.185.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
14

MacNee, W. "Premature vascular ageing in cystic fibrosis". European Respiratory Journal 34, nr 6 (30.11.2009): 1217–18. http://dx.doi.org/10.1183/09031936.00155209.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
15

Andressoo, J. O., i J. H. J. Hoeijmakers. "Transcription-coupled repair and premature ageing". Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 577, nr 1-2 (wrzesień 2005): 179–94. http://dx.doi.org/10.1016/j.mrfmmm.2005.04.004.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
16

Jones, Bryony. "Heterochromatin disorganization associated with premature ageing". Nature Reviews Genetics 16, nr 6 (18.05.2015): 318. http://dx.doi.org/10.1038/nrg3958.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
17

Cenni, Vittoria, Maria Rosaria D’Apice, Paolo Garagnani, Marta Columbaro, Giuseppe Novelli, Claudio Franceschi i Giovanna Lattanzi. "Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing". Ageing Research Reviews 42 (marzec 2018): 1–13. http://dx.doi.org/10.1016/j.arr.2017.12.001.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
18

Sauzéat, Lucie, Anne Laurençon i Vincent Balter. "Metallome evolution in ageing C. elegans and a copper stable isotope perspective". Metallomics 10, nr 3 (2018): 496–503. http://dx.doi.org/10.1039/c7mt00318h.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
19

O'Neill, Mary, Fatima Núñez i David W. Melton. "p53 and a human premature ageing disorder". Mechanisms of Ageing and Development 124, nr 5 (maj 2003): 599–603. http://dx.doi.org/10.1016/s0047-6374(03)00007-1.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
20

Toussaint, Olivier, Véronique Royer, Michel Salmon i José Remacle. "Stress-induced premature senescence and tissue ageing". Biochemical Pharmacology 64, nr 5-6 (wrzesień 2002): 1007–9. http://dx.doi.org/10.1016/s0006-2952(02)01170-x.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
21

Stewart, Colin L., Alex Chojnowski, Rafidah Mutalif, Esther Wong i Oliver Dreesen. "Premature ageing mutations at the nuclear periphery". Mechanisms of Development 145 (lipiec 2017): S3. http://dx.doi.org/10.1016/j.mod.2017.04.521.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
22

Caravia, Xurde M., David Roiz-Valle, Alba Morán-Álvarez i Carlos López-Otín. "Functional relevance of miRNAs in premature ageing". Mechanisms of Ageing and Development 168 (grudzień 2017): 10–19. http://dx.doi.org/10.1016/j.mad.2017.05.003.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
23

Hull, J., R. Garrod, T. Ho, R. Knight, J. Cockcroft, D. Shale i C. Bolton. "P2.08 PREMATURE VASCULAR AGEING IN CYSTIC FIBROSIS?" Artery Research 2, nr 3 (2008): 108. http://dx.doi.org/10.1016/j.artres.2008.08.374.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
24

De la Fuente, Mónica. "Murine models of premature ageing for the study of diet-induced immune changes: improvement of leucocyte functions in two strains of old prematurely ageing mice by dietary supplementation with sulphur-containing antioxidants". Proceedings of the Nutrition Society 69, nr 4 (28.09.2010): 651–59. http://dx.doi.org/10.1017/s0029665110003848.

Pełny tekst źródła
Streszczenie:
Several immune functions are markers of health, biological age and predictors of longevity. A chronic oxidative and inflammatory state is the main cause of ageing and the immune system is involved in the rate of ageing. Thus, several murine models of premature ageing have been proposed owing to their early immunosenescence and oxidative stress, such as ovariectomised rats and mice, obese rats and anxious mice. In the last model, the most extensively studied by us, mice showing anxiety have an aged immune function and redox status as well as a shorter longevity in comparison with animals without anxiety of the same chronological age, being denominated prematurely ageing mice. A confirmation of the above is that the administration of diets supplemented with antioxidants improves the redox status and immune functions and increases the longevity of prematurely ageing mice. Antioxidant precursors of glutathione such as thioproline or N-acetylcysteine, which have a relevant role in ageing, have been the most widely investigated in adult prematurely ageing mice in our laboratory. In the present work, we have studied the effects of the ingestion for 5 weeks of a diet supplemented with 0·1% (w/w) thioproline+N-acetylcysteine on several functions of leucocytes from chronological old (69–73 weeks of age) prematurely ageing mice of two strains (Swiss and BALB/c). The results show an improvement of the immune functions, with their values becoming closer to those in adult animals (24±2 weeks). Thus, an adequate nutrition with antioxidants, even in aged subjects, could be a good strategy to retard ageing.
Style APA, Harvard, Vancouver, ISO itp.
25

WALLIS, CORRIN V., i RICHARD G. A. FARAGHER. "Telomeres, Telomerase, and Premature Aging". Journal of Anti-Aging Medicine 3, nr 4 (styczeń 2000): 365–72. http://dx.doi.org/10.1089/rej.1.2000.3.365.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
26

E. Bauer, Moisés. "Premature immunosenescence: role of stress-related factors". PNEI REVIEW, nr 2 (listopad 2021): 20–33. http://dx.doi.org/10.3280/pnei2021-002003.

Pełny tekst źródła
Streszczenie:
The ageing of the immune system, immunosenescence, is associated with important remodelling changes in all lymphoid organs and its cells. However, the pace of ageing differs between people with the same chronological age, indicating that it may be thus influenced by extrinsic factors, including the chronic stress. In fact, young adults under chronic psychosocial stress may present immunosenescence features similarly to those found in older adults. Immunosenescence contributes to the onset and clinical course of age-related diseases such as neurodegenerative disorders, cancer, rheumatoid arthritis, cardiovascular and metabolic diseases. This article reviews that premature immunosenescence is observed in adults under chronic psychological stress as well as in healthy adolescents with history of childhood maltreatment. Superimposing stress during ageing is associated with further decline in adaptive immunity, increased inflammaging, accelerated cellular senescence and increased susceptibility to infections. This is of great interest for the COVID-19 pandemic, making the chronically stressed older adults of particular risk for worsen disease outcomes and poor vaccine responses.
Style APA, Harvard, Vancouver, ISO itp.
27

Kubben, Nard, i Tom Misteli. "Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases". Nature Reviews Molecular Cell Biology 18, nr 10 (9.08.2017): 595–609. http://dx.doi.org/10.1038/nrm.2017.68.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
28

Yu, Xin, Quantao Liu, Pei Wan, Jiangkai Song, Huan Wang, Feiyang Zhao, Yafei Wang i Jinyi Wu. "Effect of Ageing on Self-Healing Properties of Asphalt Concrete Containing Calcium Alginate/Attapulgite Composite Capsules". Materials 15, nr 4 (14.02.2022): 1414. http://dx.doi.org/10.3390/ma15041414.

Pełny tekst źródła
Streszczenie:
Calcium alginate capsules within asphalt concrete can gradually release interior asphalt rejuvenator under cyclic loading to repair micro cracks and rejuvenate aged asphalt in-situ. However, asphalt pavement will become aged due to environmental and traffic factors during the service period. In view of this, this paper investigated the effect of ageing on the healing properties of asphalt concrete containing calcium alginate/attapulgite composite capsules under cyclic loading. The capsules were fabricated using the orifice-bath method and the morphological structure, mechanical strength, thermal stability, oil release ratios and healing levels of capsules in fresh, short-term ageing and long-term ageing asphalt concrete were explored. The results indicated that the different ageing treatments would not damage the multi-chamber structure nor decrease the mechanical strength of capsules but would induce the capsules release oil prematurely. The premature oil released from capsules in turn can offset the ageing effect owing to ageing treatment. The short-term ageing and long-term ageing plain asphalt mixtures gained strength recovery ratios of 39.3% and 34.2% after 64,000 cycles of compression loading, while the strength recovery ratios of short-term ageing and long-term ageing asphalt mixtures containing capsules were 63.5% and 54.8%, respectively.
Style APA, Harvard, Vancouver, ISO itp.
29

Harte, Alison L., Nancy F. da Silva, Michelle A. Miller, Francesco P. Cappuccio, Ann Kelly, Joseph P. O’Hare, Anthony H. Barnett i in. "Telomere Length Attrition, a Marker of Biological Senescence, Is Inversely Correlated with Triglycerides and Cholesterol in South Asian Males with Type 2 Diabetes Mellitus". Experimental Diabetes Research 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/895185.

Pełny tekst źródła
Streszczenie:
South Asians have a higher risk of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) than white Caucasians, for a given BMI. Premature biological ageing, assessed by reduction in telomere length (TL), may be mediated by factors resulting from altered metabolic profiles associated with obesity. We hypothesise that ethnicity and metabolic status represent detrimental factors contributing to premature biological ageing. Therefore we assessed TL in two South Asian, age and BMI-matched cohorts [T2DM (n=142) versus non-T2DM (n=76)] to determine the effects of BMI, gender, lipid and CVD profile on biological ageing. Genomic DNA was obtained from the UKADS cohort; biochemical and anthropometric data was collected and TL was measured by quantitative real-time PCR. Our findings indicated a gender-specific effect with reduced TL in T2DM men compared with non-T2DM men (P=0.006). Additionally, in T2DM men, TL was inversely correlated with triglycerides and total cholesterol (r=−0.419,P<0.01;r=−0.443,P<0.01). In summary, TL was reduced amongst South Asian T2DM men and correlated with triglycerides and total cholesterol. This study highlights enhanced biological ageing among South Asian, T2DM men, which appears to be tracked by changes in lipids and BMI, suggesting that raised lipids and BMI may directly contribute to premature ageing.
Style APA, Harvard, Vancouver, ISO itp.
30

Roushan, Rakesh. "Association of Self Perception of Pre-Mature Ageing and Human Constitution (Prakriti) - A Cross-Sectional Study". Epidemiology International 7, nr 4 (31.12.2022): 5–11. http://dx.doi.org/10.24321/2455.7048.202214.

Pełny tekst źródła
Streszczenie:
Introduction: Premature ageing is a process associated with a progressive accumulation of deleterious changes over time, an impairment of physiologic functions, an increase in the risk of disease and death. In Ayurveda, all human beings are categorised into basic sub-seven types based on their constitution. Along with this, ageing can be accelerated by lifestyle choices and environmental conditions to which our genes are exposed. The primary objective of the cross-sectional analysis was to find the association between prakriti and self-perception of premature ageing. Methodology: For the present study, a total of 100 participants, who were found positive for self-perception of pre-mature ageing and were fulfilling the other inclusion criteria, were eligible. The analysis of self-perception of pre-mature ageing was done by using The Brief Ageing Perception Questionnaire (B-APQ). The assessment of prakriti was done with a validated Prakriti Analysis Pro forma prepared by the Central Council for Research in Ayurvedic Sciences (CCRAS), New Delhi, India. Result: The prevalence of self-perception of pre-mature ageing was maximum among vata prakriti (58, 58%) and minimum in kapha prakriti (18, 18%). A significant association of male and female participants was found with three questions of B-APQ by applying Fisher Exact test. No significant association was found between the group of vata, pitta and kapha dominant prakriti with individual B-APQ on applying independent-samples Kruskal-Wallis test. As per descriptive analysis, vata prakriti individuals were more vulnerable to the self-perception of premature ageing as per B-APQ while kapha prakriti was the least. The distribution of individual B-APQ was the same across all categories of prakriti.
Style APA, Harvard, Vancouver, ISO itp.
31

Albarrati, A., N. Gale, S. Enright, M. Munnery, I. Munnery, S. Saikia, J. Cockcroft i D. Shale. "M139 Frailty And Premature Cardiovascular Ageing In Copd". Thorax 69, Suppl 2 (10.11.2014): A212—A213. http://dx.doi.org/10.1136/thoraxjnl-2014-206260.434.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
32

Uziel, Orit, Meir Lahav, Liat Shargian, Einat Beery, Oren Pasvolsky, Uri Rozovski, Pia Raanani i Moshe Yeshurun. "Premature ageing following allogeneic hematopoietic stem cell transplantation". Bone Marrow Transplantation 55, nr 7 (24.02.2020): 1438–46. http://dx.doi.org/10.1038/s41409-020-0839-z.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
33

Wood, Heather. "Premature cellular ageing limits remyelination in progressive MS". Nature Reviews Neurology 15, nr 6 (9.04.2019): 309. http://dx.doi.org/10.1038/s41582-019-0187-z.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
34

Cupit-Link, Margaret C., James L. Kirkland, Kirsten K. Ness, Gregory T. Armstrong, Tamar Tchkonia, Nathan K. LeBrasseur, Saro H. Armenian, Kathryn J. Ruddy i Shahrukh K. Hashmi. "Biology of premature ageing in survivors of cancer". ESMO Open 2, nr 5 (listopad 2017): e000250. http://dx.doi.org/10.1136/esmoopen-2017-000250.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
35

Hamzelou, Jessica. "Italy's ‘triangle of Death’ linked to premature ageing". New Scientist 214, nr 2860 (kwiecień 2012): 10. http://dx.doi.org/10.1016/s0262-4079(12)60934-8.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
36

Morocutti, A., K. A. Earle, H. P. Rodemann i G. C. Viberti. "Premature cell ageing and evolution of diabetic nephropathy". Diabetologia 40, nr 2 (28.01.1997): 244–46. http://dx.doi.org/10.1007/s001250050670.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
37

Ebert, Thomas, Sven-Christian Pawelzik, Anna Witasp, Samsul Arefin, Sam Hobson, Karolina Kublickiene, Paul G. Shiels, Magnus Bäck i Peter Stenvinkel. "Inflammation and Premature Ageing in Chronic Kidney Disease". Toxins 12, nr 4 (4.04.2020): 227. http://dx.doi.org/10.3390/toxins12040227.

Pełny tekst źródła
Streszczenie:
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status, reduced quality of life, and premature mortality in chronic kidney disease (CKD). Because there is a huge global burden of disease due to CKD, treatment strategies targeting inflammation and premature ageing in CKD are of particular interest. Several distinct features of the uremic phenotype may represent potential treatment options to attenuate the risk of progression and poor outcome in CKD. The nuclear factor erythroid 2-related factor 2 (NRF2)–kelch-like erythroid cell-derived protein with CNC homology [ECH]-associated protein 1 (KEAP1) signaling pathway, the endocrine phosphate-fibroblast growth factor-23–klotho axis, increased cellular senescence, and impaired mitochondrial biogenesis are currently the most promising candidates, and different pharmaceutical compounds are already under evaluation. If studies in humans show beneficial effects, carefully phenotyped patients with CKD can benefit from them.
Style APA, Harvard, Vancouver, ISO itp.
38

Kooman, Jeroen P., Peter Stenvinkel i Paul G. Shiels. "Fabry Disease: A New Model of Premature Ageing?" Nephron 144, nr 1 (27.09.2019): 1–4. http://dx.doi.org/10.1159/000503290.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
39

Martens, Dries S., Harald Mischak, Tim S. Nawrot i Jan A. Staessen. "A urinary proteomic marker indicative of premature ageing". Blood Pressure Monitoring 27, Suppl 1 (25.11.2022): e9-e9. http://dx.doi.org/10.1097/01.mbp.0000905240.53184.3c.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
40

Zhang, Kexiong, Lihui Wang, Xiaojing Hong, Hao Chen, Yao Shi, Yingying Liu, Jun Liu i Jun-Ping Liu. "Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice". Cells 10, nr 11 (26.10.2021): 2892. http://dx.doi.org/10.3390/cells10112892.

Pełny tekst źródła
Streszczenie:
Pulmonary premature ageing and fibrogenesis as in idiopathic pulmonary fibrosis (IPF) occur with the DNA damage response in lungs deficient of telomerase. The molecular mechanism mediating pulmonary alveolar cell fates remains to be investigated. The present study shows that naturally occurring ageing is associated with the DNA damage response (DDR) and activation of the p53 signalling pathway. Telomerase deficiency induced by telomerase RNA component (TERC) knockout (KO) accelerates not only replicative senescence but also altered differentiation and apoptosis of the pulmonary alveolar stem cells (AEC2) in association with increased innate immune natural killer (NK) cells in TERC KO mice. TERC KO results in increased senescence-associated heterochromatin foci (SAHF) marker HP1γ, p21, p16, and apoptosis-associated cleaved caspase-3 in AEC2. However, additional deficiency of the tumour suppressor p53 in the Trp53−/− allele of the late generation of TERC KO mice attenuates the increased senescent and apoptotic markers significantly. Moreover, p53 deficiency has no significant effect on the increased gene expression of T1α (a marker of terminal differentiated AEC1) in AEC2 of the late generation of TERC KO mice. These findings demonstrate that, in natural ageing or premature ageing accelerated by telomere shortening, pulmonary senescence and IPF develop with alveolar stem cell p53-dependent premature replicative senescence, apoptosis, and p53-independent differentiation, resulting in pulmonary senescence-associated low-grade inflammation (SALI). Our studies indicate a natural ageing-associated molecular mechanism of telomerase deficiency-induced telomere DDR and SALI in pulmonary ageing and IPF.
Style APA, Harvard, Vancouver, ISO itp.
41

Li, Zirui, Zhiqiang Chen, Lianghao Zhao, Jiaqi Sun, Lin Yin, Yuwei Jiang, Xiaotong Shi, Ziye Song i Lu Zhang. "Lack of T04C9.1, the Homologue of Mammalian APPL2, Leads to Premature Ageing and Shortens Lifespan in Caenorhabditis elegans". Genes 15, nr 6 (22.05.2024): 659. http://dx.doi.org/10.3390/genes15060659.

Pełny tekst źródła
Streszczenie:
Ageing has been identified as an independent risk factor for various diseases; however, the physiological basis and molecular changes related to ageing are still largely unknown. Here, we show that the level of APPL2, an adaptor protein, is significantly reduced in the major organs of aged mice. Knocking down APPL2 causes premature ageing of human umbilical vein endothelial cells (HUVECs). We find that a lack of T04C9.1, the homologue of mammalian APPL2, leads to premature ageing, slow movements, lipid deposition, decreased resistance to stresses, and shortened lifespan in Caenorhabditis elegans (C. elegans), which are associated with decreased autophagy. Activating autophagy by rapamycin or inhibition of let-363 suppresses the age-related alternations, impaired motility, and shortened lifespan of C. elegans, which are reversed by knocking down autophagy-related genes. Our work provides evidence that APPL2 and its C. elegans homologue T04C9.1 decrease with age and reveals that a lack of T04C9.1 bridges autophagy decline and ageing in C. elegans.
Style APA, Harvard, Vancouver, ISO itp.
42

Tsunoda, Koichi, Minako Takanosawa, Yukiko Kurikawa, Kenji Nosaka i Seiji Niimi. "Hoarse voice resulting from premature ageing in Werner’s syndrome". Journal of Laryngology & Otology 114, nr 1 (styczeń 2000): 61–63. http://dx.doi.org/10.1258/0022215001903708.

Pełny tekst źródła
Streszczenie:
Werner’s syndrome is characterized by clinical signs of premature ageing. A 42-year-old man presented with three-year history of hoarseness. Also noted were skin atrophy of the face and hands, ulcerations around the ankles, and a history of cataracts. A clinical diagnosis of Werner’s syndrome was made. Laryngoscopy revealed bowed vocal folds resulting in a spindle-shaped defect with glottal incompetence during phonation. Examination also revealed decreased maximum phonation time and vocal fatigue. At surgery, atrophy of the vocalis muscle was noted. Furthermore, degeneration of muscle fibres was noted in the temporalis muscle. The atrophic changes in the vocal folds that occur with ageing and result in an increased fundamental frequency were seen in this patient. The characteristic hoarseness of Werner’s syndrome appears to be the result of premature ageing of the vocal folds.
Style APA, Harvard, Vancouver, ISO itp.
43

Manna, Samprikta, Cathal McCarthy i Fergus P. McCarthy. "Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction". Oxidative Medicine and Cellular Longevity 2019 (22.05.2019): 1–11. http://dx.doi.org/10.1155/2019/3095383.

Pełny tekst źródła
Streszczenie:
Preeclampsia is a multisystemic pregnancy disorder and a major cause of maternal and neonatal morbidity and mortality worldwide. The exact pathophysiology of preeclampsia remains unclear; however, it is speculated that the various pathologies can be attributed to impaired vascular remodelling and elevated oxidative stress within the placenta. Oxidative stress plays a key role in cell ageing, and the persistent presence of elevated oxidative stress precipitates cellular senescence and mitochondrial dysfunction, resulting in premature ageing of the placenta. Premature ageing of the placenta is associated with placental insufficiency, which reduces the functional capacity of this critical organ and leads to abnormal pregnancy outcomes. The changes brought about by oxidative insults are irreversible and often lead to deleterious modifications in macromolecules such as lipids and proteins, DNA mutations, and alteration of mitochondrial functioning and dynamics. In this review, we have summarized the current knowledge of placental ageing in the aetiology of adverse pregnancy outcomes and discussed the hallmarks of ageing which could be potential markers for preeclampsia and fetal growth restriction.
Style APA, Harvard, Vancouver, ISO itp.
44

Anisimov, Vladimir. "Premature Ageing Prevention: Limitations and Perspectives of Pharmacological Interventions". Current Drug Targets 7, nr 11 (1.11.2006): 1485–503. http://dx.doi.org/10.2174/1389450110607011485.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
45

Varshney, Iti, Mohammad Adil, Syed Suhail Amin, Mohd Mohtashim, Annu Priya i Mahtab Alam. "Hutchinson-Gilford progeria syndrome: a rare premature ageing syndrome". Dermatology Review 107, nr 2 (2020): 179–83. http://dx.doi.org/10.5114/dr.2020.96361.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
46

Pashinyan, A. G., S. A. Heidar, G. B. Arutyunyan i Ye V. Dontsova. "Skin moisturizing as a factor preventing premature skin ageing". Vestnik dermatologii i venerologii 89, nr 4 (15.08.2013): 104–7. http://dx.doi.org/10.25208/vdv634.

Pełny tekst źródła
Streszczenie:
The authors describe issues related to age-related changes in the skin. They present data confirming the clinical efficacy of hydration cosmetic drugs belonging to the Noreva Aquareva line by Laboratoires Dermatologiques d’Uriage aimed at renewing the natural moisture-preserving epidermis structure in patients with dry skin within a short period of time.
Style APA, Harvard, Vancouver, ISO itp.
47

&NA;. "PUVA may induce premature ageing and nonmelanoma skin cancers". Reactions Weekly &NA;, nr 313 (sierpień 1990): 3. http://dx.doi.org/10.2165/00128415-199003130-00006.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
48

Green, Adèle C. "Premature ageing of the skin in a Queensland population". Medical Journal of Australia 155, nr 7 (październik 1991): 473–78. http://dx.doi.org/10.5694/j.1326-5377.1991.tb93845.x.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
49

Dotti, Maria Teresa, Gerald Salen i Antonio Federico. "Cerebrotendinous Xanthomatous as a Multisystem Disease Mimicking Premature Ageing". Developmental Neuroscience 13, nr 4-5 (1991): 371–76. http://dx.doi.org/10.1159/000112187.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
50

Trifunovic, Aleksandra, Anna Wredenberg, Maria Falkenberg, Johannes N. Spelbrink, Anja T. Rovio, Carl E. Bruder, Mohammad Bohlooly-Y i in. "Premature ageing in mice expressing defective mitochondrial DNA polymerase". Nature 429, nr 6990 (maj 2004): 417–23. http://dx.doi.org/10.1038/nature02517.

Pełny tekst źródła
Style APA, Harvard, Vancouver, ISO itp.
Oferujemy zniżki na wszystkie plany premium dla autorów, których prace zostały uwzględnione w tematycznych zestawieniach literatury. Skontaktuj się z nami, aby uzyskać unikalny kod promocyjny!

Do bibliografii