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Artykuły w czasopismach na temat "Polypyridyl Oxovanadium(IV) Complexes"

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Banerjee, Samya, Ila Pant, Imran Khan, Puja Prasad, Akhtar Hussain, Paturu Kondaiah i Akhil R. Chakravarty. "Remarkable enhancement in photocytotoxicity and hydrolytic stability of curcumin on binding to an oxovanadium(iv) moiety". Dalton Transactions 44, nr 9 (2015): 4108–22. http://dx.doi.org/10.1039/c4dt02165g.

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Yuan, Caixia, Liping Lu, Yanbo Wu, Zhiwei Liu, Maolin Guo, Shu Xing, Xueqi Fu i Miaoli Zhu. "Synthesis, characterization, and protein tyrosine phosphatases inhibition activities of oxovanadium(IV) complexes with Schiff base and polypyridyl derivatives". Journal of Inorganic Biochemistry 104, nr 9 (wrzesień 2010): 978–86. http://dx.doi.org/10.1016/j.jinorgbio.2010.05.003.

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Lu, Liping, Jinjun Yue, Caixia Yuan, Miaoli Zhu, Hong Han, Zhiwei Liu i Maolin Guo. "Ternary oxovanadium(IV) complexes with amino acid-Schiff base and polypyridyl derivatives: Synthesis, characterization, and protein tyrosine phosphatase 1B inhibition". Journal of Inorganic Biochemistry 105, nr 10 (październik 2011): 1323–28. http://dx.doi.org/10.1016/j.jinorgbio.2011.07.008.

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Yuan, Caixia, Liping Lu, Xiaoli Gao, Yanbo Wu, Maolin Guo, Ying Li, Xueqi Fu i Miaoli Zhu. "Ternary oxovanadium(IV) complexes of ONO-donor Schiff base and polypyridyl derivatives as protein tyrosine phosphatase inhibitors: synthesis, characterization, and biological activities". JBIC Journal of Biological Inorganic Chemistry 14, nr 6 (17.03.2009): 841–51. http://dx.doi.org/10.1007/s00775-009-0496-6.

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Ohde, Christian, Christian Limberg, Reinhard Stösser i Serhiy Demeshko. "Oxovanadium(IV) Silsesquioxane Complexes". Inorganic Chemistry 49, nr 5 (marzec 2010): 2479–85. http://dx.doi.org/10.1021/ic902392y.

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Baran, Enrique J. "OXOVANADIUM(IV) COMPLEXES OF CARBOHYDRATES". Journal of Carbohydrate Chemistry 20, nr 9 (31.12.2001): 769–88. http://dx.doi.org/10.1081/car-100108656.

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Williams, Patricia A. M., Evelina G. Ferrer i Enrique J. Baran. "OXOVANADIUM(IV) COMPLEXES OF CAPTOPRIL". Journal of Coordination Chemistry 42, nr 4 (1.11.1997): 261–69. http://dx.doi.org/10.1080/00958979708022856.

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Pandya, Bhavna J., i Pabitra K. Bhattacharya. "Binary and ternary complexes of oxovanadium(IV) and homobinuclear double-bridged oxovanadium(IV) complexes". Transition Metal Chemistry 12, nr 5 (październik 1987): 398–400. http://dx.doi.org/10.1007/bf01171645.

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Mishra, Mahendra Kumar, Ruchita Tripathi, Pandeya Kb i Tripathi Ip. "α-AMYLASE INHIBITION AND ELECTROCHEMICAL BEHAVIOR OF SOME OXOVANADIUM (IV) COMPLEXES OF L-AMINO ACIDS". Asian Journal of Pharmaceutical and Clinical Research 11, nr 8 (7.08.2018): 218. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.25800.

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Objective: Diabetes is complex metabolic disease having a symptom of hyperglycemia. Oxovanadium (IV) and l-amino acids are used to normalize the hyperglycemic condition. The aim of this study was to screen the α-amylase inhibitory activity of l-amino acids, their oxovanadium (IV) complexes, and electrochemical activity of oxovanadium (IV) complexes.Methods: All the oxovanadium (IV) complexes were synthesized according to the solubility of l-amino acids; the molar ratio of metal to l-amino acid was 1:2. The synthesized oxovanadium (IV) complexes were examined for their electrochemical behavior in 0.01 M sodium perchlorate solution. Further, the oxovanadium (IV) complexes of l-amino acids and l-amino acids were screened for their α-amylase inhibitory activity using spectrophotometric assay system.Results: The synthesized complexes were divided into four groups according to nature of amino acids. Entire complexes show simple irreversible wave for VO redox couples in −900–50 mV potential range and scan rate was 300 mV/S. All the complexes and l-amino acids were screened for their α-amylase inhibitory activity. L-Histidine and their oxovanadium (IV) complex show the minimum IC50 value, i.e. 4199.05 μM and 101.015 μM, respectively, in their respective groups.Conclusion: The data obtained from our study, it reveals that the entire oxovanadium (IV) complexes are an irreversible wave for VO redox system and the l-histidine and its oxovanadium (IV) complex is the most potent inhibitor for the α-amylase. Further, the complexes show minimum IC50 value on comparing their respective ligands due to the interaction of Vanadyl complex to the enzyme, at the sixth vacant position of Vanadyl complex.
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Hasan, M. F., A. M. Seyam i H. A. Hodali. "Oxovanadium(IV) Complexes with Azooxime Ligands". Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 26, nr 2 (1.02.1996): 181–89. http://dx.doi.org/10.1080/00945719608004257.

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Rozprawy doktorskie na temat "Polypyridyl Oxovanadium(IV) Complexes"

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Choudhary, Nosheen Fatima. "The chemistry of oxovanadium(IV) tetradentate Schiff base complexes". Thesis, University of Sussex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244319.

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Walmsley, Ryan Steven. "An investigation into the antidiabetic and catalytic properties of oxovanadium(IV) complexes". Thesis, Rhodes University, 2012. http://hdl.handle.net/10962/d1004978.

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In part 1 of this thesis, the antidiabetic activity of a series of novel oxovanadium(IV) complexes was investigated. A range of bidentate N,O-donor ligands, which partially mimic naturally occurring bioligands, were prepared and reacted with the vanadyl ion to form the corresponding bis-coordinated complexes. Initially, 2-(2ˊ-hydroxyphenyl)-1R-imidazoline (where R = H, ethyl and ethanol) ligands were prepared. The aqueous pH-metric chemical speciation was investigated using glass electrode potentiometry which allowed for the determination of protonation and stability constants of the ligands and complexes, respectively. The species distribution diagrams generated from this information gave an indication of how the complexes might behave across the broad pH range experienced in the digestive and circulatory systems. This information was used to create an improved 2nd generation of ligands that were constructed by combining the imidazole and carboxylic acid functionalities. These corresponding bis[(imidazolyl)carboxylato]-oxovanadium(IV) complexes displayed a broader pH-metric stability. Both sets of complexes improved glucose uptake and reduced coagulation in vitro. In part 2 of this thesis, a range of homogeneous and heterogeneous oxovanadium(IV) catalysts were prepared. Firstly, Merrifield beads were functionalized with ligands from Part 1 and then reacted with vanadyl sulfate to afford the corresponding heterogeneous catalysts. These displayed promising catalytic activity for the peroxide facilitated oxidation of thioanisole, styrene and ethylbenzene as well as the oxidative bromination of phenol red. Smaller imidazole-containing beads with higher surface areas than the Merrifield beads were prepared by suspension polymerization. These beads similarly demonstrated excellent catalytic activity for the oxidation of thioanisole and were highly recyclable. In attempt to increase the exposed catalytic surface area, while retaining the ease of separation achieved in the before mentioned systems, micron to nano sized electrospun fibers containing coordinating ligands were fabricated. The corresponding oxovanadium(IV) functionalized fibers were applied to the oxidation of thioanisole using a continuous flow system. The flexible and porous nature of the fiber mats was well suited to this approach. After optimization of the reactant flow rate and catalyst amount, near quantitative (> 99%) oxidation was achieved for an extended period. In addition, leaching of vanadium was mitigated by modification of the attached ligand or polymer material.
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Alvino, De la Sota Nora, i Calderón Javier Pacheco. "Diseño de Agentes Antidiabéticos de Vanadio: Desarrollo y Avances Recientes". Revista de Química, 2007. http://repositorio.pucp.edu.pe/index/handle/123456789/100688.

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El descubrimient o del mayor efecto hipoglicémic o del bis(maltolato)oxovanadio (IV) (BMOV) con respecto a las salesde vanadio, propició el diseño, síntesis y evaluación in vitro e in vivo de una amplia variedad de complejos de oxovanadio(IV) con diversos ligandos orgánicos para su potencial uso como fármacos antidiabéticos que reemplacen , parcial ototalmente , las incómodas inyecciones de insulina en el tratamiento de la diabetes mellitus tipo 1 o los fármacos oraleshipoglicemiante s empleados generalment e en terapias combinadas para la tipo 2.Recientemente , un complejo etil sustituido , análogo al BMOV, ha completado favorablemente la fase clínica I deensayos en humanos. El diseño de nuevos tipos de complejos y el desarrollo de nuevos modos de administración constituyenactualmente un activo campo de investigación
Design of Vanadium Antidiabetic Agents: Development and Recent AdvancesThe discovery of the enhanced hypoglycemic activity of bis(maltolate)oxovanadiu m (IV) (BMOV) compared to simplevanadium salts stimulated the design, synthesis and both in vitro and in vivo evaluation of a large variety of oxovanadium (IV)complexes with different organic ligands for their potential use as antidiabetic drugs that may be able to substitute, either partially or totally, the daily insulin injections used in the treatment of type 1 diabetes mellitus or the orally available hypoglycemic drugs usually used in combined therapy for type 2 diabetes.Recently, a close BMOV analogue, an ethyl substitute, has already successfully completed the phase 1 clinical trial in humans. The design of new types of complexes and the development of alternative delivery methods represent an active research field today.
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Lima, Silvânia Marilene de. "Novos catalisadores à base de oxovanádio (IV) e Cucurbit[6]urila". Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-01092009-111752/.

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As cucurbiturilas são moléculas versáteis empregadas em diversos ramos da química, essas gaiolas moleculares formam uma família de homólogos oriundos da condensação da glicolurila e do formaldeído em meio ácido. As aplicações se estendem para campos como catálise, fotoquímica, sínteses orgânica e inorgânica, química de materiais e supramolecular. Particularmente a cucurbit[6]urila, comumente chamada apenas de CB[6], uma molécula bastante simétrica, têm em seus opérculos, sítios propícios à coordenação, especialmente com espécies pequenas e pouco polarizáveis. Aproveitando o caráter dos portais, foi possível sintetizar um complexo inédito, com um sítio catalítico proveniente de íons vanadila, VO2+, ligados às extremidades do cavitando. O acesso ao centro catalítico desta molécula, seria determinado pela captura do substrato no interior do macrociclo, limitado pelo volume do substrato e pelas relações de solvofobicidade, pois a cavidade possui um caráter hidrofóbico. A estrutura desse complexo ainda não foi completamente elucidada, pois não foi possível obter um cristal único e determiná-la através de difração de raios-x. As técnicas de caracterização no estado sólido empregadas indicaram que esse novo complexo teria o seu centro metálico provavelmente numa configuração piramidal de base retangular, isso é evidenciado pelas medidas espectroscópicas que remetem a uma simetria C2V. Foram feitas tentativas de coordenação mono e binuclear, mas algumas técnicas apontam para a formação apenas da espécie mononuclear. Os primeiros testes catalíticos, em condições brandas para a conversão de hidrocarbonetos apresentaram bons resultados frente a substratos lineares e inatividade frente a substratos cíclicos mais volumosos. Os resultados obtidos nos levam a crer que as reações de oxidação de alcanos, com estas espécies, se dão pelo interior da cavidade, ao longo do orbital dz2 do íon (V=O)2+, e não pela parte superior através do átomo de oxigênio ligado ao vanádio.
Cucurbiturils are versatile molecules used in several branches of chemistry. These molecular cages form a family of homologues from the condensation of glycoluril and formaldehyde in acidic medium. Their applications range from catalysis, photochemistry, organic and inorganic synthesis, materials and supramolecular chemistry. Particularly cucurbit[6]uril, or simply CB[6], is a very symmetrical molecule, which posesses coordination points on its portals, especially with hard acids. Due to this characteristic, it was possible to synthesize a new complex, with a vanadyl, VO2+, catalytic center bonded to the extremity of the cavitand. The access to the catalytic center of this molecule should be determined by the entrance of the substrate inside the macrocycle, which is limited by its volume and by solvophobicity, because the cavity is strongly hydrophobic. The structure of this new complex could not be completely solved yet, because it was impossible to obtain a single crystal for X-rays diffraction analysis. The solid state characterization techniques indicated that this new complex has its metallic center in a rectangular-base pyramid configuration. This was shown by the spectroscopic evidences which point to a d1 ion in a C2V symmetry. Attempts were made to synthesize both mono and binuclear species, but all the techniques we have used have demonstrated that only the former one was obtained. The first catalytic tests for hydrocarbons convertion in mild conditions have shown good results towards for linear substrates and no activity at all towards more volumous cyclic molecules. The results we have obtained indicate that the alkane oxidation reactions with these complexes occur inside the cavity along the (V=O)2+ ion dz2 orbital , and not on its superior moiety on the vanadyl oxygen atom.
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Bouhsina, Saâd. "Pouvoir complexant des sucres acides avec les ions métalliques. Complexation de l'acide lactobionique avec les ions cuivre(II) et oxovanadium(IV)". Lille 1, 1991. http://www.theses.fr/1991LIL10174.

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Les carbohydrates sont des substances produites en grande quantité dans l'environnement. Lorsqu'ils possèdent un point d'ancrage: une fonction amine ou une fonction carboxylique comme dans le cas des sucres acides ou aminés, ils complexent bien les ions métalliques. On sait que ces derniers sont essentiels dans les processus biologiques. Chaque espèce vivante (flore, faune) est caractérisée par une concentration optimale de ces ions. Une surconcentration ou au contraire une carence se traduit par des troubles du métabolisme. Il existe fort heureusement des systèmes régulateurs de la concentration en ions métalliques. Lorsque ceux-ci sont défaillants il faut alors faire diminuer dans l'organisme l'ion métallique ou le lui fournir sous forme assimilable. L'un des produits les plus utilisés en pharmacopée est le gluconate du métal. On pense que l'acide lactobionique pourrait constituer un substitut intéressant de l'acide gluconique. Les études reportées dans ce mémoire décrivent les propriétés complexantes de l'acide lactobionique vis-à-vis des ions cuivrique et oxovanadium. Ces travaux prennent en compte l'équilibre cinétique de cet acide avec sa lactone. Une dernière partie traite de la formation de complexes avec les sucres aminés
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何嘉麗 i Clare Ho. "Reactivities and kinetic studies on high valent ruthenium(IV), (V) and(VI) oxo complexes of chelating tertiary amine, polypyridyl andporphyrinato ligands". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31232577.

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Ho, Clare. "Reactivities and kinetic studies on high valent ruthenium(IV), (V) and (VI) oxo complexes of chelating tertiary amine, polypyridyl and porphyrinato ligands /". [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13154102.

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Zhou, Ying. "Oxovanadium(IV) and (V) complexes with naturally-occurring molecules". Thesis, 1993. http://hdl.handle.net/2429/2608.

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Complexes with naturally-occurring ligating moieties were prepared and studied aspart of an overall process to understand the coordination chemistry of vanadium. Bis(kojato) oxovanadium(IV), VO(ka)2, bis(3-oxy-1,2-dimethy1-4-pyridinonato)-oxovanadium(IV), VO(dpp)2, bis(2-hydroxymethy1-5-oxy-1-methy1-4-pyridinonato)-oxovanadium(IV), VO(hmp)2, bis[2-(2'-oxypheny1)-2-oxazolinato]oxovanadium(IV),VO(oz)2, bis[2-(2'-oxypheny1)-2-thiazolinato]oxovanadium(IV), VO(thz)2.0.5H20 and bis(benzohydroxamato) oxovanadium(IV), VO(bz)2 were prepared and characterized. In addition, two oxovanadium(V) complexes, bis(benzohydroxamato) methoxo-oxovanadium(V), V0(OCH3)(bz)2 and bis(benzohydroxamato) ethoxooxovanadium(V), VO(0C2H5)(bz)2 were also prepared from VO(bz)2. All eight complexes were prepared in one step processes, in particular V0(dpp)2 and V0(hmp)2 which were prepared directly from maltol and kojic acid, respectively, using vanadyl and methylamine in a one-potsynthesis method. All oxovanadium complexes were characterized by infrared spectroscopy, mass spectrometry, elemental analyses and room temperature magnetic susceptibility measurements, and whenever possible, by UV-Visible spectrophotometry. 1H and 51VNMR were also used to characterize the two oxovanadium(V) complexes,VO(OCH3)(bz)2 and VO(0C2H5)(bz)2. Single crystal X-ray diffraction studies ofVO(oz)2 and V0(thz)2 were also performed by the departmental facility. Characterization of the oxovanadium(IV) complexes revealed them to be 5-coordinate square pyramidal bis(ligand) oxovanadium(IV) complexes with each ligand binding in a bidentate fashion to the central vanadium atom. VO(OCH3)(bz)2 and V0(0C2H5)(bz)2 were found to be 6-coordinate bis(ligand) oxovanadium(V) complexes. Comparison of the infrared stretching frequencies of the vanadium-oxo bond revealed that the strength of the vanadium-oxo bond in the eight complexes was consistent with bond strength observed in other oxovanadium complexes. Single crystal X-ray diffraction studies of VO(0z)2 and VO(thz)2 showed them to be isostructural. The bidentate ligands are bonded to the vanadium center through the phenolate oxygen and the oxazoline orthiazoline ring nitrogen. The two complexes are both regular square pyramids with the bidentate ligands coordinated in a trans fashion. The vanadium atoms in these complexes are elevated by approximately 0.6 A from the basal square planes defined by the four ligand 0 and N donors. The average V=0 bond length is 1.6 A.
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Hon, Sang-Wen, i 洪三文. "Catalytic Asymmetric Coupling of 2-Naphthols by Chiral Tridentate Oxovanadium(IV) Complexes". Thesis, 2001. http://ndltd.ncl.edu.tw/handle/62659171488582496658.

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博士
國立臺灣師範大學
化學研究所
89
A series of chiral oxovanadium(IV) complexes derived from tridentate N-3,5-substituted and N-3,4-benzo- and N-5,6-benzo-salicylidene-α-amino acids can serve as efficient catalysts for the enantioselective oxidative couplings of various 3-,6-,7-substituted- 2-naphthols under O2. We take the reseach about the solvent effect,cooxidant effect,amino acid effect….and so on in detail. Our catalyst in the coupling reaction of 2-naphthol is the best methodology as we know. The best scenario involves the use of a vanadyl complex arising from 2-hydroxy-1-naphtholaldehyde and valine (or phenylalanine) in CCl4, leading to BINOLs in good yields (75-100%) and with enantioselectivities of up to 68%.
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Prasad, Puja. "Studies on Near-IR Light Photocytotoxic Oxovanadium Complexes". Thesis, 2013. http://etd.iisc.ernet.in/2005/3379.

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The present thesis deals with different aspects of the chemistry of oxovanadium(IV) complexes, their interaction with double stranded DNA, photo-induced DNA cleavage, photo-enhanced cytotoxicity in visible light and red light and localisation and cellular uptake to understand the mechanism of cell death. Chapter I presents a general introduction on potential of transition metal complexes as photochemotherapeutic agents. A brief introduction about Photodynamic Therapy (PDT) as a new alternative to chemotherapy for treating cancer has been made. Various modes of interaction of small molecules with duplex DNA are described. Recent reports on metal-based photocytotoxicity, photo-induced DNA cleavage activity and cellular localization are presented in detail. Objective of the present investigation is also dealt in this Chapter. Chapter II of the thesis deals with the synthesis, characterization, DNA binding and photo-induced DNA cleavage activity of ternary oxovanadium(IV) complexes of ONO-donor 2-(2-hydroxybenzylideneamino)phenol (salamp) and phenanthroline bases to explore the photo-induced DNA cleavage activity in UV-A light of 365 nm and photocytotoxicity in visible light. Chapter III deals with the photo-induced DNA cleavage and photocytotoxicity of ternary oxovanadium(IV) complexes containing ONN-donor N-2-pyridylmethylidine-2-hydroxyphenylamine (Hpyamp) Schiff bases and phenanthroline bases. The objective of this work is to investigate the photo-induced DNA cleavage activity in near-IR light. Photocytotoxicity and cell cycle arrest have been studied in HeLa cancer cells. Chapter IV deals serendipitous discovery of planar triazinuim cationic species by vanadyl-assisted novel ring cyclization reaction. The compounds are synthesised, characterized and their DNA binding and anaerobic photoinduced DNA cleavage activity are presented. The importance of the thiazole moiety in the triazinuim species in cellular uptake has been investigated. Photocytotoxicity, localization and cell death mechanism have been studied in HeLa and MCF-7 cells. Chapter V describes the synthesis, characterization, DNA binding, photo-induced DNA cleavage activity and photocytotoxicity of oxovanadium(IV) complexes containing 2-(1H-benzimidazol-2-yl)-N-(pyridin-2-ylmethylene)ethaneamine (Hpy-aebmz) and curcumin as photosensitizer. The effect of conjugating naphthalimide on Hpy-aebmz on photoinduced DNA cleavage and photocytotoxicity has been studied. Cellular uptake, localization and mechanism of cell death induced by complexes have been investigated. Chapter VI presents ternary oxovanadium(IV) complexes having, 2-((1H-benzimidazol-2-yl)methylimino-methyl)phenol (Hsal-ambmz) and phenanthroline bases. The complexes were synthesized, characterized and their DNA binding property studied. Photo-induced DNA cleavage activity and photocytotoxicity in red light has been discussed. Anthracene has been conjugated to a tridentate ligand to investigate cellular uptake, localization and cell death mechanism. Mitochondria targeting property of the complexes having dipeptide has been studied and compared with clinically used drug Photofrin®. The references have been compiled at the end of each chapter and indicated as superscript numbers in the text. The complexes presented in this thesis are represented by bold-faced numbers. Crystallographic data of the complexes, characterized structurally by single crystal X-ray crystallography, are given in CIF format in the enclosed CD (Appendix-I). Due acknowledgements have been made wherever the work described is based on the findings of other investigators. Any unintentional omission that might have happened due to oversight or mistake is regretted.
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Części książek na temat "Polypyridyl Oxovanadium(IV) Complexes"

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Thompson, Katherine H., Barry D. Liboiron, Graeme R. Hanson i Chris Orvig. "In Vivo Coordination Chemistry and Biolocalization of Bis(ligand)oxovanadium(IV) Complexes for Diabetes Treatment". W ACS Symposium Series, 384–99. Washington, DC: American Chemical Society, 2005. http://dx.doi.org/10.1021/bk-2005-0903.ch021.

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Thompson, K. H., J. H. McNeill i C. Orvig. "Design of New Oxovanadium (IV) Complexes for Treatment of Diabetes. Biovailability, Speciation, and Tissue Targeting Considerations". W Trace Elements in Man and Animals 10, 539. New York, NY: Springer US, 2002. http://dx.doi.org/10.1007/0-306-47466-2_172.

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Sakurai, Hiromu. "Structure-Activity Relationship and Molecular Action Mechanism in the Family of Antidiabeticbis(Picolinato)oxovanadium(IV) Complexes". W Vanadium: The Versatile Metal, 110–20. Washington, DC: American Chemical Society, 2007. http://dx.doi.org/10.1021/bk-2007-0974.ch009.

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Streszczenia konferencji na temat "Polypyridyl Oxovanadium(IV) Complexes"

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Puri, Rojila. "Synthesis and characterization of some mixed-ligand oxovanadium (IV) complexes of carbodithioate ligands and 1,10- phenanthroline or 2,2′–bipyridyl". W INTERNATIONAL CONFERENCE ON ADVANCES IN MULTI-DISCIPLINARY SCIENCES AND ENGINEERING RESEARCH: ICAMSER-2021. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0095311.

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