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Artykuły w czasopismach na temat „Polymeric Nanocolloids”

Autor: Grafiati

Data publikacji: 6 września 2023

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Sprawdź 22 najlepszych artykułów w czasopismach naukowych na temat „Polymeric Nanocolloids”.

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1

Vergaro, Viviana, Francesca Baldassarre, Federica De Castro, Danilo Migoni, Maria Michela Dell’Anna, Piero Mastrorilli, Francesco Paolo Fanizzi i Giuseppe Ciccarella. "Low-Intensity Light-Responsive Anticancer Activity of Platinum(II) Complex Nanocolloids on 2D and 3D In Vitro Cancer Cell Model". Bioinorganic Chemistry and Applications 2022 (23.04.2022): 1–15. http://dx.doi.org/10.1155/2022/9571217.

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This study aimed to evaluate the therapeutic efficacy of low-intensity visible light responsive nanocolloids of a Pt-based drug using a 2D and three-dimensional (3D) in vitro cancer cell model. Biocompatible and biodegradable polymeric nanocolloids, obtained using the ultrasonication method coupled with Layer by Layer technology, were characterized in terms of size (100 ± 20 nm), physical stability, drug loading (78%), and photoactivation through spectroscopy studies. The in vitro biological effects were assessed in terms of efficacy, apoptosis induction, and DNA-Pt adducts formation. Biological experiments were performed both in dark and under visible light irradiation conditions, exploiting the complex photochemical properties. The light-stimuli responsive nanoformulation gave a significant enhancement in drug bioactivity. This allowed us to achieve satisfying results by using nanomolar drug concentration (50 nM), which was ineffective in darkness condition. Furthermore, our nanocolloids were validated in 3D in vitro spheroids using confocal microscopy and cytofluorimetric assay to compare their behavior on culture in 2D monolayers. The obtained results confirmed that these nanocolloids are promising tools for delivering Pt-based drugs.

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Sahoo, Satyajeet, Anitha Gopalan, S. Ramesh, P. Nirmala, G. Ramkumar, S. Agnes Shifani, Ram Subbiah i J. Isaac JoshuaRamesh Lalvani. "Preparation of Polymeric Nanomaterials Using Emulsion Polymerization". Advances in Materials Science and Engineering 2021 (8.10.2021): 1–9. http://dx.doi.org/10.1155/2021/1539230.

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Nanoparticles are said to be active particles which are entrapped in the surface of the polymeric core. Since nanoparticles were used in medical and biotechnological fields, there is a great demand in the preparation of nanoparticles. Nanoparticles are prepared from different substances; mainly, polymer material is used in the field of preparing nanomaterials. There are different methods involved in the preparation of nanoparticles from the polymer. Various experiments and research studies were carried out on the basic preparation of nanoparticles. Emulsion polymerization could be used to make polymeric nanoparticles with a high solid concentration without the need of surfactants. To make carboxylate polystyrene beads or amidine polystyrene nanoparticles, polymeric nanocolloids containing surface functional groups were produced. In this research, the preparation of nanoparticles from emulsion polymerization is represented along with the size and distribution material.

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Begam, Nafisa, Sivasurender Chandran, M. Sprung i J. K. Basu. "Anomalous Viscosity Reduction and Hydrodynamic Interactions of Polymeric Nanocolloids in Polymers". Macromolecules 48, nr 18 (28.08.2015): 6646–51. http://dx.doi.org/10.1021/acs.macromol.5b00759.

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4

Lee, Demei, Ming-Yi Hsu, Ya-Ling Tang i Shih-Jung Liu. "Manufacture of Binary Nanofeatured Polymeric Films Using Nanosphere Lithography and Ultraviolet Roller Imprinting". Materials 14, nr 7 (29.03.2021): 1669. http://dx.doi.org/10.3390/ma14071669.

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This paper describes the manufacture of binary nanostructured films utilizing nanosphere lithography and ultraviolet (UV) roller imprinting. To manufacture the binary nanofeatured template, polystyrene nanocolloids of two distinct dimensions (900 and 300 nm) were primarily self-assembly spun coated on a silicon substrate. A roller imprinting facility equipped with polydimethylsiloxane molds and ultraviolet radiation was employed. During the imprinting procedure, the roller was steered by a motor and compressed the ultraviolet-curable polymeric layer against the glass substrate, where the nanofeatured layer was cured by the UV light source. Binary nanofeatured films were thus obtained. The influence of distinct processing variables on the imprinting of nanofeatured films was investigated. The empirical data suggested that with appropriate processing conditions, binary nanofeatured plastic films can be satisfactorily manufactured. It also demonstrated that roller imprinting combined with ultraviolet radiation can offer an easy yet effective method to prepare binary nanofeatured films, with a miniatured processing time and enhanced part quality.

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5

Lee, Demei, Ya-Ling Tang i Shih-Jung Liu. "Fast Fabrication of Nanostructured Films Using Nanocolloid Lithography and UV Soft Mold Roller Embossing: Effects of Processing Parameters". Polymers 13, nr 3 (27.01.2021): 405. http://dx.doi.org/10.3390/polym13030405.

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We report the fabrication of nanofeatured polymeric films using nanosphere lithography and ultraviolet (UV) soft-mold roller embossing and show an illuminative example of their application to solar cells. To prepare the nanofeatured template, polystyrene nanocolloids of two distinct sizes (900 and 300 nm) were overlaid on silicon substrates using a spin coater. A lab-made soft-mold roller embossing device equipped with a UV light source was adopted. A casting method was employed to replicate the nanofeatured template onto polydimethylsiloxane, which was used as the soft mold. During the embossing procedure, the roller was driven by a step motor and compressed the UV-curable resin against the glass substrate to form the nanofeatured layer, which was subsequently cured by UV radiation. Polymer films with nanoscaled features were thus obtained. The influence of distinct processing variables on the reproducibility of the nanofeatured films was explored. The empirical outcomes demonstrate that UV soft-mold roller embossing offers a simple yet potent way of producing nanofeatured films.

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6

Anuța, Valentina, Marina-Theodora Talianu, Cristina-Elena Dinu-Pîrvu, Mihaela Violeta Ghica, Răzvan Mihai Prisada, Mădălina Georgiana Albu Kaya i Lăcrămioara Popa. "Molecular Mapping of Antifungal Mechanisms Accessing Biomaterials and New Agents to Target Oral Candidiasis". International Journal of Molecular Sciences 23, nr 14 (7.07.2022): 7520. http://dx.doi.org/10.3390/ijms23147520.

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Oral candidiasis has a high rate of development, especially in immunocompromised patients. Immunosuppressive and cytotoxic therapies in hospitalized HIV and cancer patients are known to induce the poor management of adverse reactions, where local and systemic candidiasis become highly resistant to conventional antifungal therapy. The development of oral candidiasis is triggered by several mechanisms that determine oral epithelium imbalances, resulting in poor local defense and a delayed immune system response. As a result, pathogenic fungi colonies disseminate and form resistant biofilms, promoting serious challenges in initiating a proper therapeutic protocol. Hence, this study of the literature aimed to discuss possibilities and new trends through antifungal therapy for buccal drug administration. A large number of studies explored the antifungal activity of new agents or synergic components that may enhance the effect of classic drugs. It was of significant interest to find connections between smart biomaterials and their activity, to find molecular responses and mechanisms that can conquer the multidrug resistance of fungi strains, and to transpose them into a molecular map. Overall, attention is focused on the nanocolloids domain, nanoparticles, nanocomposite synthesis, and the design of polymeric platforms to satisfy sustained antifungal activity and high biocompatibility with the oral mucosa.

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7

Fazio, Enza, Alessandro Ridolfo i Giulia Neri. "Thermally Activated Noble Metal Nanoparticles Incorporated in Electrospun Fiber-based Drug Delivery Systems". Current Nanomaterials 4, nr 1 (11.07.2019): 21–31. http://dx.doi.org/10.2174/1573407214666180914121929.

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Background: Nanosystems based on PEG-PLGA copolymer have attracted increasing interest in several biomedicine fields, due to their unique properties. Commonly, PEG-PLGA copolymer was used to formulate nanoparticles (NPs) for drug delivery applications. Only recently, the engineering of polymeric nanofibrous membrane able to be use like drug nanocarrier was investigated. Objective: The goal of this work is the development of two new drug delivery systems based on PEGylated-PLGA nanofibrous scaffolds, obtained by electrospinning deposition, simultaneous loaded with: i) silibinin, a therapeutic agent, ii) Au/Ag and iii) non-toxic Fe2O3 magnetic nanoparticles. Another interest aspect of the present work regards how the morphological structure can influence the drug release which has been fine-tuned by two external stimuli: a light source and a magnetic field. Methods: Noble metal nanocolloids were prepared in water by the pulsed laser ablation technique. The PEG-PLGA@Au/Ag-SLB added with Fe2O3-PVA nanofibers were fabricated by the electrospinning deposition method. Results: The use of “Surface Plasmon Resonance”-mediated localized photothermal effect, determined by the nanoparticles resonant absorption of visible radiation, allows to these systems to be able to employ for photothermal drug delivery therapies in proximity of tumor cells. All data obtained about the fiber scaffolds are compared to NPs based on the same PEG-PLGA copolymer, loaded with silibinin, Fe2O3 and Au/Ag nanoparticles alternatively. Nanofibers respects to NPs, showed interesting sustained responsive silibinin release for at least 60 h, without the burst effect. A diffusion-based theoretical model approach allowed to precisely describe the release mechanism. Conclusion: The effective and controlled silibilin drug release, upon application of either light irradiation or magnetic field for a definite time interval, has been demonstrated. Under the light stimulus, the fiber-shaped nanosystem reached a cumulative drug release value as high as 70% in the long time. On the overall, the information obtained could be useful to design suitable “on demand” nanocomposites in view of a therapeutic treatments protocol that requires a fast pharmacological action.

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8

Belloni, Jacqueline. "Metal nanocolloids". Current Opinion in Colloid & Interface Science 1, nr 2 (kwiecień 1996): 184–96. http://dx.doi.org/10.1016/s1359-0294(96)80003-3.

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9

Civallero, Monica, Viviana Vergaro, Cinzia Citti, Maria Cosenza, Giuseppe Cannazza, Carlo Parenti, Alessia Bari, Giuseppe Ciccarella, Stefano Sacchi i Samantha Pozzi. "Calcium-Carbonate Nanocapsules Improve the Efficacy of BEZ235 in Lymphoma a Cell Line: A Promising New Technology of Drug Delivery". Blood 126, nr 23 (3.12.2015): 4851. http://dx.doi.org/10.1182/blood.v126.23.4851.4851.

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Abstract Nanotechnology is a promising branch of the medical field, directed to improve diagnostic and therapeutics strategies, applying nanovectors as drug delivery systems. Efficient encapsulation of anticancer drugs in nanocolloids and microcapsules was recently developed by G. Ciccarella research group (1). Based on our collaboration with the Nantional Nanotechnology Laboratory of the University of Salento and our previous experience with target therapies, we encapsulated BEZ235, a phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin inhibitor (mTOR). BEZ235 efficiently blocks the dysfunctional activation of the PI3K/mTOR pathway in cellular and in vivo settings, thus inhibiting the growth and proliferation of various cancer cells, and phase I/II clinical trials were open in solid cancer. However the scarse solubility limited further development of this promising compound. In order to overcome the solubility issue BEZ235-loaded nanocapsules were generated by the stepwise adsorption of oppositely charged polyelectrolytes into biocompatible CaCO3 cores. First nanocapsules were tested for biocompatibility. The exposition of lymphoma cell lines to empty nanocapsules up to 48 hours, did not induce any cititoxicity, confirming their biocompatibility. Second, encapsulated BEZ235 was compared with free-drug to test the cytotoxicity in a T lymphoma cell line (HUT78) by MTT assay (Fig. 1). The results suggested that nanoencapsulated-BEZ235 was extremely efficient compared with free-BEZ235, reaching IC50 just after 5 hours of exposure compared with an IC65% at 48 hours with the free drug. A validated LC-MS/MS method was developed in order to quantify intracellular concentration of BEZ235 over time. Intracellular concentration of BEZ235 in the lymphoma cell line was consistent with biological results since the internalization kinetic and efficiency was increased by the coating. In order to confirm that the encapsuled-BEZ235 was still effective on cell apoptosis, we tested free BEZ and encapsulated BEZ235 at a concentration of 1µM in T cell lymphoma cell lines. Encapsulated-BEZ235 induced apoptosis evidenced by the cleavage of caspase 8, 9 and 3 at an earlier time point compared with free BEZ235 and at significantly lower concentration. We also confirmed that the encapsulated-BEZ235 maintained its effect on the target mTOR/AKT pathway: p-AKT was dephosphorylated at 5h while the free BEZ235 operates at least after 24 hours at concentrations 100 times higher, as previously demonstrated (2). Keeping in mind a future clinical application of these polymeric particles/capsules, our data can be regarded as a promising new nanotechnology-based strategy to improve the efficacy and bioavailability of old and new drugs. Functional biological studies of BEZ235-encapsulated carrier and its mechanism of internalization are already under way, and animal in vivo studies to evaluated toxicity and distribution of the nanocapsuled compound are ongoing. 1 F. Baldassare et al., Macromolecular Bioscience, Volume 12, Issue 5, pages 656-665, 2012 2 Civallero M, Cosenza M, Marcheselli L, Pozzi S, Sacchi S. Expert Opin Investig Drugs. 2012 Nov;21(11):1597-606. Disclosures No relevant conflicts of interest to declare.

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10

DENKBAŞ, EMIR B., i A. VASEASHTA. "NANOTECHNOLOGY IN MEDICINE AND HEALTH SCIENCES". Nano 03, nr 04 (sierpień 2008): 263–69. http://dx.doi.org/10.1142/s1793292008001313.

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The present investigation is aimed at the biomedical aspects of nanomaterials in medicine and health sciences. Synthesis of nanomaterials can be categorized into three main sections based on their system designation, viz. nanocolloidal systems, surface modification of the biomaterials at molecular level, and nanodevices. An overview of functionalized nanomaterials, devices, and systems in drug and gene delivery, controlled release systems, molecular imaging and diagnostics, cardiac therapy, dental care, orthopedics, and targeted cancer therapy is presented. We further present some preliminary results of our investigation of biodegradable polymeric nanospheres and nanofibers with significant applications in health and medicine.

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11

Zhang, Han, i Xin-lin Yang. "Magnetic polymer microsphere stabilized gold nanocolloids as a facilely recoverable catalyst". Chinese Journal of Polymer Science 29, nr 3 (31.01.2011): 342–51. http://dx.doi.org/10.1007/s10118-011-1036-8.

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12

Li, Guorong, i Bogeng Li. "First Successful Post-Synthetic Self-Assembly of Polyaniline with Poly(N-vinylpyrrolidone) into Aqueous Nanocolloids". Macromolecular Rapid Communications 27, nr 11 (2.06.2006): 854–58. http://dx.doi.org/10.1002/marc.200600125.

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13

Parakkal, Fasalurahman, Blessy Babukutty, Basiluddeen Azad Vettiyadan, Nandakumar Kalarikkal i Swapna S. Nair. "Experimental investigation of optical and magneto optical effects of chemically synthesized cobalt nanocolloids". Materials Research Express 3, nr 4 (22.04.2016): 045020. http://dx.doi.org/10.1088/2053-1591/3/4/045020.

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14

Koushki, E., i A. Farzaneh. "Numerical simulation of optical dispersion, group velocity, and waveguide properties of gold and silver nanocolloids and hybrids". Colloid and Polymer Science 295, nr 1 (12.12.2016): 197–203. http://dx.doi.org/10.1007/s00396-016-3991-7.

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15

Quant, Carlos A., i J. Carson Meredith. "Attractive Nanocolloid−Polymer Mixtures: Comparison of a Modified Perturbed Lennard-Jones Equation of State to Monte Carlo Simulation". Macromolecules 38, nr 1 (styczeń 2005): 167–73. http://dx.doi.org/10.1021/ma0482213.

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Babić Radić, Marija M., Vuk V. Filipović, Marija Vukomanović, Jasmina Nikodinović Runić i Simonida Lj Tomić. "Degradable 2-Hydroxyethyl Methacrylate/Gelatin/Alginate Hydrogels Infused by Nanocolloidal Graphene Oxide as Promising Drug Delivery and Scaffolding Biomaterials". Gels 8, nr 1 (27.12.2021): 22. http://dx.doi.org/10.3390/gels8010022.

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The design and evaluation of novel 2-hydroxyethyl methacrylate/gelatin/alginate/graphene oxide hydrogels as innovative scaffolding biomaterials, which concurrently are the suitable drug delivery carrier, was proposed. The hydrogels were prepared by the adapted porogen leaching method; this is also the first time this method has been used to incorporate nanocolloidal graphene oxide through the hydrogel and simultaneously form porous structures. The effects of a material’s composition on its chemical, morphological, mechanical, and swelling properties, as well as on cell viability and in vitro degradation, were assessed using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), measurements of Young’s modulus, gravimetric method and MTT test, respectively. The engineered hydrogels show good swelling capacity, fully hydrophilic surfaces, tunable porosity (from 56 to 76%) and mechanical properties (from 1.69 to 4.78 MPa), curcumin entrapment efficiency above 99% and excellent curcumin release performances. In vitro cytotoxicity on healthy human fibroblast (MRC5 cells) by MTT test reveal that the materials are nontoxic and biocompatible, proposing novel hydrogels for in vivo clinical evaluation to optimize tissue regeneration treatments by coupling the hydrogels with cells and different active agents to create material/biofactor hybrids with new levels of biofunctionality.

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Maruthamuthu, S., J. Chandrasekaran, D. Manoharan, SN Karthick, Hee-Je Kim i B. Saravanakumar. "CuBr2-induced charge screening on photoactive nanocolloidal polypyrrole:poly(styrene sulfonate) composite multilayer thin-film counter electrodes for high-efficiency dye-sensitized solar cells". Polymer International 65, nr 5 (18.03.2016): 584–95. http://dx.doi.org/10.1002/pi.5098.

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Maruthamuthu, S., J. Chandrasekaran, D. Manoharan i R. Magesh. "Conductivity and dielectric analysis of nanocolloidal polypyrrole particles functionalized with higher weight percentage of poly(styrene sulfonate) using the dispersion polymerization method". Journal of Polymer Engineering 37, nr 5 (24.05.2017): 481–92. http://dx.doi.org/10.1515/polyeng-2015-0321.

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Abstract Nanocolloidal polypyrrole/poly(styrene sulfonate) PPy:PSS composites were prepared by dispersion polymerization of pyrrole with 0.5 wt%, 1 wt%, 2.5 wt%, 5 wt%, 10 wt% and 15 wt% of PSS. Higher doping level of PPy was confirmed with increased S/N value of elemental analysis. Morphological variations of PPy composite matrix based on PSS were analyzed in which spherical shaped PPy particles of 20–40 nm were obtained for 1:1 wt% of PPy:PSS. Presence of higher concentration of PSS within the PPy matrix substantially improved its thermal stability. Dielectric properties were investigated using complex impedance analyzer as a function of frequency (50 Hz–5 MHz) and temperature between 30°C and 120°C. PPy, with improved dispersion, showed higher dielectric constant values up to 15 wt% of anionic polyelectrolyte PSS and the dielectric loss varied between 4.7 and 7.9 for different wt% of PSS. AC conductivity (σac) enhanced up to 1:1 wt% of PPy:PSS composite, which is found to be the optimum wt% in this study. DC conductivity was found to decrease after 1:1 wt% of PPy:PSS composite, which is due to excess oxidation, leading to reduced π conjugation of PPy chains. Higher dielectric constant values of composite, with relatively low dielectric loss values, indicate their potential usage in the electric and electronic industry.

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Riest, Jonas, Labrini Athanasopoulou, Sergei A. Egorov, Christos N. Likos i Primož Ziherl. "Elasticity of polymeric nanocolloidal particles". Scientific Reports 5, nr 1 (2.11.2015). http://dx.doi.org/10.1038/srep15854.

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Gunjan Vasant, Bonde, Ajmal Gufran, Yadav Sarita Kumari, Mittal Pooja i Mishra Brahmeshwar. "Lapatinib-loaded nanocolloidal polymeric micelles for the efficient treatment of breast cancer". Journal of Applied Pharmaceutical Science, 4.09.2020. http://dx.doi.org/10.7324/japs.2020.10903.

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Marla, Krishna T., i James C. Meredith. "Modeling Self-Assembly of Nanoparticle Structures: Simulation of Nanoparticle Chemical Potentials in Polymer-Nanoparticle Mixtures". MRS Proceedings 740 (2002). http://dx.doi.org/10.1557/proc-740-i7.3.

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ABSTRACTThe expanded ensemble Monte Carlo (EEMC) simulation method has been applied to calculation of the chemical potential of nanocolloidal particles in the presence of polymeric surface modifiers. Two general classes of surface modifiers have been studied – nonadsorbing and freely-adsorbing. For both systems, the infinite dilution colloid chemical potential was calculated as a function of the colloid diameter and the modifier chain length. The colloid chemical potential was found to decrease with increasing modifier chain length for both types of modifiers, albeit for different reasons. Empirical power-law scaling relationships were found to represent the simulation results well. A physical interpretation was proposed for the power law exponents obtained in the case of adsorbing modifiers.

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Huang, Yuhang, Sofia M. Morozova, Terek Li, Shangyu Li, Hani E. Naguib i Eugenia Kumacheva. "Stimulus-Responsive Transport Properties of Nanocolloidal Hydrogels". Biomacromolecules, 29.12.2022. http://dx.doi.org/10.1021/acs.biomac.2c01222.

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