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1

Mowery, Ann C. Techniques for determining segmental characteristics in a kinematic analysis of the golf drive. Eugene: Microform Publications, College of Human Development and Performance, University of Oregon, 1986.

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Association, Canadian Medical, red. Physicians' guide to driver examination. Wyd. 5. Ottawa: Canadian Medical Association, 1991.

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Forensic aspects of driver perception and response. Tucson, AZ: Lawyers & Judges Pub. Co., 1996.

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Olson, Paul L. Forensic aspects of driver perception and response. Wyd. 2. Tucson, AZ: Lawyers & Judges Pub. Co., 2003.

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Forensic aspects of driver inexperience and accident causation. Tucson, Ariz: Lawyers & Judges Pub. Company, 2011.

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Peterson, Melinda M. Modifying hostility-causing beliefs, aggression, danger ratings, and physiological arousal with an aggressive driver prevention program. Sudbury, Ont: Laurentian University, Department of Psychology, 2002.

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Robert, Dewar, i Farber Gene, red. Forensic aspects of driver perception and response. Wyd. 3. Tucson, Ariz: Lawyers & Judges Pub., 2010.

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8

United States. National Transportation Safety Board. Fatigue, alcohol, other drugs, and medical factors in fatal-to-the-driver heavy truck crashes. Washington, D.C: The Board, 1990.

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J, Hanowski Richard, United States. Federal Motor Carrier Safety Administration. i Virginia Polytechnic Institute and State University. Transportation Institute., red. Impact of local short haul operations on driver fatigue. Washington, D.C: U.S. Dept. of Transportation, Federal Motor Carrier Safety Administration, 2000.

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Automotive ergonomics: Driver-vehicle interaction. Boca Raton: CRC Press, 2013.

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Balkin, T. Effects of sleep schedules on commercial motor vehicle driver performance. Washington, D.C: U.S. Dept. of Transportation, Federal Motor Carrier Safety Administration, 2000.

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The Hunger Type Diet: Discover what drives your hunger, rebalance your hormones - and lose weight for good. London: Watkins Media Ltd, 2015.

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Whitfield, James F. Calcium: Cell cycle driver, differentiator, and killer. New York: Chapman and Hall, 1997.

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14

Kerckhoffs, Roy C. P. Patient specific modeling of the cardiovascular system: Technology-driven personalized medicine. New York: Springer, 2010.

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Pape, Douglas B. Role of human factors in preventing cargo tank truck rollovers. Washington, D.C: Transportation Research Board, 2012.

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G, Gale Alastair, Applied Vision Association (Great Britain), Ergonomics Society (Great Britain) i Association of Optometrists (Great Britain), red. Vision in vehicles-IV. Amsterdam: North-Holland, 1993.

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17

Drive Thru Diet. New Horizons Publishing, 2002.

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18

Creagh-Brown, Benedict, Joerg Steier i Nicholas Hart. Prolonged Weaning. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0049.

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In 25% of critically ill patients, weaning from mechanical ventilation takes longer than 10 days; indeed, 5–10% of patients still require ventilation at 30 days. Those with prolonged weaning, after adjustment for other variables, have a higher mortality within the intensive care unit than those without weaning delay or failure. The pathophysiological processes that result in weaning failure are complex and result of an imbalance between the neural respiratory drive, respiratory muscle load, and capacity. The clinical conditions resulting in these pathophysiological conditions should be methodically considered in patients requiring prolonged weaning. These patients often need a personalized weaning and rehabilitation approach, based on their underlying pathological condition as well as their psychological and physiological status.
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19

Association, Canadian Medical, red. Physicians' guide to driver examination. Ottawa: Canadian Medical Association, 1986.

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McDermid, Robert C., i Sean M. Bagshaw. Physiological Reserve and Frailty in Critical Illness. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0028.

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Physicians have long sought to define a ‘physiologic age’ distinct from chronologic age which might account for some of the variance in response to critical illness and injury. This has led to the concept of ‘physiologic reserve’ which might represent a major driver of outcome in patients requiring intensive care. The human body is a complex system that adapts to a multitude of external stressors; however, senescence or illness can reduce inherent adaptive mechanisms, reducing complexity and reducing the threshold for decompensation (i.e. acute illness or injury). This theoretical critical threshold can be considered ‘physiologic reserve’. The phenotypic expression of this process is frailty. Frailty is a condition in which small deficits accumulate which individually may be insignificant but collectively produce an overwhelming burden of disease and heightened vulnerability to adverse events. Frail patients expend a greater proportion of their reserve simply to maintain homeostasis, and seemingly trivial insults can contribute to catastrophic decompensation. While frailty has generally been described among older populations, the concept of frailty as a surrogate of physiologic reserve may have relevance to critically ill patients across a wide spectrum of age. Research is needed to characterize the biological underpinnings of frailty, optimal ways to measure it, and its importance in determining survival and functional outcomes after critical illness. The utilization of ICU resources by older patients is rising, and the prevalence of frailty in those admitted to the ICU is likely to increase.
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21

D, Wylie C., United States. Federal Highway Administration. i Canada Transport Canada, red. Commercial motor vehicle driver fatigue and alertness study. Washington, D.C: The Administration, Transport Canada, 1996.

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22

Patrick, Graham J. NEURONAL REGULATION AND ATTENTION DEFICIT DISORDER: AN APPLICATION OF PHOTIC DRIVEN EEG NEUROTHERAPY. 1994.

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23

Schulkin, Jay. Radical Change. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780198793694.003.0004.

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Chapter 4 talks about how CRF is involved in two quite striking processes: metamorphosis and parturition. Both of these processes revolve around the wondrously vital feature of radical change. In both instances, we are discussing the changing of form and the maturation of an organism. While one change is ancient and one more modern, both continue to be important features of life on this planet, and they represent the importance of development and its responsiveness to changing environments. Our story of metamorphosis, however, is about change and adaptation or preadaptation and the expansion of use and capability. CRF is fundamentally tied to the world in which animals are adapting to changes including the seasons, times of day, droughts, and breeding cycles. Cycles of stability and change set the conditions for adaptive viability; underlying such events is predictive coherence, where diverse information molecules drive physiological and behavioral adaptations.
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24

Driver Rehabilitation: A Guide for Assessment and Intervention. Therapy Skill Builders, 2003.

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Gkikas, Nikolaos. Automotive Ergonomics: Driver-Vehicle Interaction. Taylor & Francis Group, 2017.

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Gkikas, Nikolaos. Automotive Ergonomics: Driver-Vehicle Interaction. Taylor & Francis Group, 2016.

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Gkikas, Nikolaos. Automotive Ergonomics: Driver-Vehicle Interaction. Taylor & Francis Group, 2016.

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Gkikas, Nikolaos. Automotive Ergonomics: Driver-Vehicle Interaction. Taylor & Francis Group, 2012.

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29

Krauss, David. Forensic Aspects of Driver Perception and Response, Fourth Edition. Lawyers & Judges Publishing Company, Inc., 2015.

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30

Mills, Gary H. Pulmonary disease and anaesthesia. Redaktor Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0082.

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Respiratory adverse events are the commonest complications after anaesthesia and have profound implications for the recovery of the patient and their subsequent health. Outcome prediction related to respiratory disease and complications is vital when determining the risk:benefit balance of surgery and providing informed consent. Surgery produces an inflammatory response and pain, which affects the respiratory system. Anaesthesia produces atelectasis, decreases the drive to breathe, and causes muscle weakness. As the respiratory system ages, closing capacity increases and airway closure becomes an increasing issue, resulting in atelectasis. Increasing comorbidity and polypharmacy reduces the patient’s ability to eliminate drugs. The proportion of major operations on older frailer patients is rising and postoperative recovery becomes more complicated and the demand for critical care rises. At the same time, the population is becoming more obese, producing rapid decreases in end-expiratory lung volume on induction, together with a high incidence of sleep-disordered breathing. Despite this, many high-risk patients are not accurately identified preoperatively, and of those that are admitted to critical care, some are discharged and then readmitted to the intensive care unit with complications. Respiratory diseases may lead to increases in pulmonary vascular resistance and increased load on the right heart. Some lung diseases are primarily fibrotic or obstructive. Some are inflammatory, autoimmune, or vasculitic. Other diseases relate to the drive to breathe, the nerve supply to, or the respiratory muscles themselves. The range of types of respiratory disease is wide and the physiological consequences of respiratory support are complex. Research continues into the best modes of respiratory support in theatre and in the postoperative period and how best to protect the normal lung. It is therefore essential to understand the effects of surgery and anaesthesia and how this impacts existing respiratory disease, and the way this affects the balance between load on the respiratory system and its capacity to cope.
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31

The impact of medical impairments on driving and driver licensing: Report to the Commissioner. [Albany, N.Y.?]: NYS Dept. of Motor Vehicles, 1990.

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32

Long, Michael E., 1963- author, red. The molecule of more: How a single chemical in your brain drives love, sex, and creativity-and will determine the fate of the human race. BenBella Books, 2018.

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33

Cubides-Amézquita, Jenner Rodrigo, red. Characterizing the fitness of Colombian military personnel. Escuela Militar de Cadetes José María Córdova, 2021. http://dx.doi.org/10.21830/9789585380240.

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One of the great limitations in applying research involving the military population is that data are taken from other studies that do not reflect the specific characteristics or conditions of Colombian soldiers. Regardless, the outcomes are applied and appropriated as if these soldiers were, in fact, the sample of the study. In response to this situation, this work publishes the results of research involving the physical performance of Colombian military personnel to provide the academic community with descriptions of the variables that make up this population’s physical fitness training. This work is a first attempt to characterize their physical, physiological, and biomechanical capabilities using the best available evidence and state-of-the-art technology. One of this book’s main contributions to military physical training knowledge is that it is the first initiative to evaluate Colombian military personnel’s level of physical training. The scientific rigor of the studies in this compilation allows the reproducibility of the tests (external validity). It paves the way for a series of studies in military physical performance and health-related factors concerning active members of the National Army, seeking to characterize, evaluate, and determine training programs to optimize the institution’s pillars of doctrine. The ultimate goal is to drive the improvement of soldiers’ physical conditions, favoring a better quality of life and safety in operational performance.
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34

L, Neale Vicki, United States. Federal Motor Carrier Safety Administration. i Virginia Polytechnic Institute and State University. Transportation Institute., red. Impact of sleeper berth usage on driver fatigue: Task 1 report: analysis of trucker sleep quality. Washington, D.C: U.S. Dept. of Transportation, Federal Motor Carrier Safety Administration, 2000.

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35

Heim, Christine, i Charles B. Nemeroff. Neurobiological Pathways Involved in Fear, Stress, and PTSD. Redaktorzy Israel Liberzon i Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0012.

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The symptoms of post-traumatic stress disorder (PTSD) are believed to reflect an inadequate adaptation of neurobiological systems to exposure to severe stressors. A vast number of studies have revealed multiple alterations in neuroendocrine and neurochemical systems in patients with PTSD. It is now evident that certain neurobiological changes in PTSD actually reflect preexisting vulnerability factors that contribute to maladaptive physiological and behavioral responses to traumatic exposure, as well as altered learning and extinction of fear memories. These results suggest the development of novel pathophysiology-driven strategies for intervention that directly target the neurobiological mechanisms that lead to stress sensitization, increased fear memories, and arousal.
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Kerckhoffs, Roy C. P. Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine. Springer, 2014.

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37

Madden, Anthony P. Informatics and technology for anaesthesia. Redaktor Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0034.

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Health informatics is concerned with the structure, acquisition, and use of health information. Its origins can be traced back to the publication of Bills of Mortality by the parishes of London in the sixteenth century. Interest in health information accelerated during the late nineteenth century with the development of an internationally recognized classification of the causes of death. Further work on the classification of diseases and causes of death has resulted in the ICD-10, while SNOMED CT provides an international thesaurus of medical terms suitable for use in computerized medical record systems. In 1932, Tovell and Dunn described the systematic collection of data about anaesthetics with the aim of identifying areas for improvement. The improvement of healthcare is the main driver for the implementation of electronic patient record systems in hospitals. A natural corollary is the implementation of computerized anaesthetic information management systems. Computerized record systems can automatically store the output of physiological monitors and reduce errors with active and passive decision support. Although the recording and processing of health information in the twenty-first century almost always involves the use of computers, this can give rise to problems with security and inter-operability. Computer technology also has other uses in modern anaesthetic practice. The modelling of physiological processes and the use of simulators in the training of anaesthetists are good examples.
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38

Whitfield, James F. Calcium: Cell Cycle Driver, Differentiator, Killer (Molecular Biology Intelligence Unit). Chapman & Hall, 1997.

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Khalsa, Sahib S., i Justin S. Feinstein. The somatic error hypothesis of anxiety. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198811930.003.0008.

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A regulatory battle for control ensues in the central nervous system following a mismatch between the current physiological state of an organism as mapped in viscerosensory brain regions and the predicted body state as computed in visceromotor control regions. The discrepancy between the predicted and current body state (i.e. the “somatic error”) signals a need for corrective action, motivating changes in both cognition and behavior. This chapter argues that anxiety disorders are fundamentally driven by somatic errors that fail to be adaptively regulated, leaving the organism in a state of dissonance where the predicted body state is perpetually out of line with the current body state. Repeated failures to quell somatic error can result in long-term changes to interoceptive circuitry within the brain. This chapter explores the neuropsychiatric sequelae that can emerge following chronic allostatic dysregulation of somatic errors and discusses novel therapies that might help to correct this dysregulation.
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40

Whitfield, James F. Calcium: Cell Cycle Driver, Differentiator and Killer (Molecular Biology Intelligence Unit). Landes Bioscience, 1997.

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Esler, Karen J., Anna L. Jacobsen i R. Brandon Pratt. Organisms and their Interactions. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198739135.003.0003.

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Both animal and plant species exhibit adaptive traits related to features of mediterranean-type ecosystems (MTEs). For plants, the seasonality of the MTC has been an important factor in the evolution of plant phenological traits. Root adaptive traits that improve nutrient extraction from impoverished soils are present within MTC regions, including cluster roots, root nodules, and mycorrhizal symbioses. Fire has been an important driver of plant traits, such as smoke, charate, or heat-induced seed germination or seed release (i.e. serotiny), and post-fire flowering. Adaptive traits in animals include both physiological and behavioural traits. MTC regions have been used in the study of many ecological and evolutionary patterns, particularly as related to organismal adaptations to unique soil and substrates (edaphic communities) and interactions between plants and animals, such as plant–herbivore interactions, plant–pollinator interactions, and plant–seed disperser interactions. These interactions shape many plant and animal characters within MTC regions.
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Brown, I. D., C. M. Haslegrave, S. P. Taylor i H. W. Kruysse. Vision in Vehicles IV (Vision in Vehicles). North Holland, 1993.

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43

Vermeulen, Roel, Douglas A. Bell, Dean P. Jones, Montserrat Garcia-Closas, Avrum Spira, Teresa W. Wang, Martyn T. Smith, Qing Lan i Nathaniel Rothman. Application of Biomarkers in Cancer Epidemiology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0006.

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Advancements in OMICs are now enabling investigators to explore comprehensively the biological consequences of exogenous and endogenous exposures by detecting molecular signatures of exposure, early signs of adverse biological effects, preclinical disease, and molecularly defined cancer subtypes. These new technologies have proven invaluable for assembling a comprehensive portrait of human exposure, health, and disease. This includes hypothesis-driven biomarkers, as well as platforms that can agnostically analyze entire biologic processes and “compartments,” including the measurement of small molecules (metabolomics), DNA polymorphisms and rarer inherited variants (genomics), methylation and microRNA (epigenomics), chromosome-wide alterations, mRNA (transcriptomics), proteins (proteomics), and the microbiome (microbiomics). Although the implementation of these technologies in epidemiologic studies has already shown great promise, some challenges of particular importance must be addressed. Non-genetic OMIC markers vary over time due to both random variation and physiologic changes. Therefore, there is an urgent need for cohorts to collect repeat biological samples over time.
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Bion, Julian, i Anna Dennis. ICU admission and discharge criteria. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0020.

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The decision to admit patients to intensive care or discharge them, is a daily task for intensivists, a life-changing event for patients and families, and a major strategic issue for health care systems worldwide. Decisions must often be made rapidly, in conditions of uncertainty, involving substituted judgements about relative risks and benefits, framed by sociocultural factors that are not well characterized. The outcomes are strongly influenced by available resources, staffing, and skills throughout the patient pathway. The decision to admit should be based on the severity of illness, chronic health and physiological reserve, and therapeutic susceptibility, informed by the patient’s wishes. Discharge decisions are equally complex and involve balancing the needs of individual patients against those of society. Scoring systems and guidelines can aid decision making. The process involves collaboration between intensivist, referring team, patient, and family. The provision of futile care is usually driven by family expectations and lack of agreement among the treating team. Discussions involve value judgements. Effective admission and discharge processes will minimize avoidable morbidity, mortality, and readmissions, and maximize family and patient satisfaction, and cost-efficacy. However, reaching the most effective level of practice involves balances and compromises. Experienced clinical judgement remains a key element in defining suitability of individual patients for ICU admission and discharge.
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Thomas, Dafydd, i Katy Beard. Blood conservation and transfusion in anaesthesia. Redaktor Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0051.

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Over the last three decades, avoidance of allogeneic transfusion in order to decrease adverse events within the recipient has become a part of clinical care. Although the main driver was an avoidance of transfusion-transmitted disease, other immunological consequences have been noted, and it is widely regarded as desirable to avoid the use of allogeneic component transfusion unless there is an essential physiological need. Of course this attempt at decreasing allogeneic blood component use has a potentially beneficial effect of blood component supply, leading to decreased use within the surgical specialties, while allowing increased use in clinical cases where there is currently no alternative to the transfusion of allogeneic components, such as those cases who have received chemotherapy and marrow suppression. The development of an array of techniques and treatments to decrease dependence of blood component transfusion has led to a care pathway that attempts to treat preoperative anaemia, minimize operative blood loss, and withhold allogeneic transfusion in the postoperative period according to clinical need. Many questions remain about the appropriate level of haemoglobin depending upon the comorbidities suffered by the patient, which is why patient blood management has gained popularity, as each patient deserves an individual care plan according to need.
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Kirchman, David L. Genomes and meta-omics for microbes. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789406.003.0005.

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The sequencing of entire genomes of microbes grown in pure cultures is now routine. The sequence data from cultivated microbes have provided insights into these microbes and their uncultivated relatives. Sequencing studies have found that bacterial genomes range from 0.18 Mb (intracellular symbiont) to 13 Mb (a soil bacterium), whereas genomes of eukaryotes are much bigger. Genomes from eukaryotes and prokaryotes are organized quite differently. While bacteria and their small genomes often grow faster than eukaryotes, there is no correlation between genome size and growth rates among the bacteria examined so far. Genomic studies have also highlighted the importance of genes exchanged (“horizontal gene transfer”) between organisms, seemingly unrelated, as defined by rRNA gene sequences. Microbial ecologists use metagenomics to sequence all microbes in a community. This approach has revealed unsuspected physiological processes in microbes, such as the occurrence of a light-driven proton pump, rhodopsin, in bacteria (dubbed proteorhodopsin). Genomes from single cells isolated by flow cytometry have also provided insights about the ecophysiology of both bacteria and protists. Oligotrophic bacteria have streamlined genomes, which are usually small but with a high fraction of genomic material devoted to protein-encoding genes, and few transcriptional control mechanisms. The study of all transcripts from a natural community, metatranscriptomics, has been informative about the response of eukaryotes as well as bacteria to changing environmental conditions.
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Buzsáki, György. The Brain from Inside Out. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190905385.001.0001.

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The Brain from Inside Out takes a critical look at contemporary brain research and reminds us that theoretical framework does matter. Current technology-driven neuroscience is still largely fueled by an empiricist philosophy assuming that the brain’s goal is to perceive, represent the world, and learn the truth. An inevitable consequence of this framework is the assumption of a decision-making homunculus wedged between our perception and actions. In contrast, The Brain from Inside Out advocates that the brain’s fundamental function is to induce actions and predict the consequences of those actions to support the survival and prosperity of the brain’s host. Brains constantly test their hypotheses by producing actions rather than searching for the veridical objective world. Only actions can provide a second opinion about the relevance of the sensory inputs and provide meaning for and interpretation of those inputs. In this inside-out framework, it is not sensations that teach the brain and build up its circuits. Instead, the brain comes with a preconfigured and self-organized dynamics that constrains how it acts and views the world. Both its anatomical and physiological organizations are characterized by an enormous diversity which spans several orders of magnitude. The two ends of this continuous landscape give rise to apparently distinct qualitative features. A small core of strongly interconnected, highly active neurons provides fast and “good-enough” answers in needy situations by generalizations, whereas detailed and precise solutions rely on the contribution of the more isolated and sluggish majority. In this non-egalitarian organization, preexisting nonsense brain patterns become meaningful through action-based experience. The inside-out framework offers an alternative strategy to investigate how brain operations give rise to our cognitive faculties, as opposed to the outside-in approach that explores how our preconceived ideas map onto brain structures.
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Fedosov, Anton. Supporting the Design of Technology-Mediated Sharing Practices. Carl Grossmann, 2020. http://dx.doi.org/10.24921/2020.94115943.

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Online social networks have made sharing personal experiences with others mostly in form of photos and comments a common activity. The convergenceof social, mobile, cloud and wearable computing expanded the scope of usergeneratedand shared content on the net from personal media to individual preferencesto physiological details (e.g., in the form of daily workouts) to informationabout real-world possessions (e.g., apartments, cars). Once everydaythings become increasingly networked (i.e., the Internet of Things), future onlineservices and connected devices will only expand the set of things to share. Given that a new generation of sharing services is about to emerge, it is of crucialimportance to provide service designers with the right insights to adequatelysupport novel sharing practices. This work explores these practices within twoemergent sharing domains: (1) personal activity tracking and (2) sharing economyservices. The goal of this dissertation is to understand current practices ofsharing personal digital and physical possessions, and to uncover correspondingend-user needs and concerns across novel sharing practices, in order to map thedesign space to support emergent and future sharing needs. We address this goalby adopting two research strategies, one using a bottom-up approach, the otherfollowing a top-down approach.In the bottom-up approach, we examine in-depth novel sharing practices within two emergent sharing domains through a set of empirical qualitative studies.We offer a rich and descriptive account of peoples sharing routines and characterizethe specific role of interactive technologies that support or inhibit sharingin those domains. We then design, develop, and deploy several technology prototypesthat afford digital and physical sharing with the view to informing the design of future sharing services and tools within two domains, personal activitytracking and sharing economy services.In the top-down approach, drawing on scholarship in human-computer interaction (HCI) and interaction design, we systematically examine prior workon current technology-mediated sharing practices and identify a set of commonalitiesand differences among sharing digital and physical artifacts. Based uponthese findings, we further argue that many challenges and issues that are presentin digital online sharing are also highly relevant for the physical sharing in thecontext of the sharing economy, especially when the shared physical objects havedigital representations and are mediated by an online platform. To account forthese particularities, we develop and field-test an action-driven toolkit for designpractitioners to both support the creation of future sharing economy platformsand services, as well as to improve the user experience of existing services.This dissertation should be of particular interest to HCI and interaction designresearchers who are critically exploring technology-mediated sharing practicesthrough fieldwork studies, as well to design practitioners who are building and evaluating sharing economy services.
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