Artykuły w czasopismach na temat „PDE2A”
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Skryabin, Egor B., Kirstie A. De Jong, Hariharan Subramanian, Nadja I. Bork, Alexander Froese, Boris V. Skryabin i Viacheslav O. Nikolaev. "CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms". Cells 12, nr 11 (4.06.2023): 1543. http://dx.doi.org/10.3390/cells12111543.
Pełny tekst źródłaIvey, F. Douglas, Lili Wang, Didem Demirbas, Christina Allain i Charles S. Hoffman. "Development of a Fission Yeast-Based High-Throughput Screen to Identify Chemical Regulators of cAMP Phosphodiesterases". Journal of Biomolecular Screening 13, nr 1 (26.11.2007): 62–71. http://dx.doi.org/10.1177/1087057107312127.
Pełny tekst źródłaManns, J. M., K. J. Brennan, S. B. Sheth i R. W. Colman. "Differential Regulation of Human Platelet Responses by cGMP Inhibited and Stimulated cAMP Phosphodiesterases". Thrombosis and Haemostasis 87, nr 05 (2002): 873–79. http://dx.doi.org/10.1055/s-0037-1613099.
Pełny tekst źródłaCarvalho, Thays Maria da Conceição Silva, Silvia Cardarelli, Mauro Giorgi, Andrea Lenzi, Andrea M. Isidori i Fabio Naro. "Phosphodiesterases Expression during Murine Cardiac Development". International Journal of Molecular Sciences 22, nr 5 (5.03.2021): 2593. http://dx.doi.org/10.3390/ijms22052593.
Pełny tekst źródłaChen, Ling, Suying Cui, Haiyang Yu, Gaowen Li, Na Liu, Qiang Wu, Han-Ting Zhang, James M. O’Donnell, Gang Wang i Ying Xu. "Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice". Journal of Psychopharmacology 33, nr 5 (5.03.2019): 568–76. http://dx.doi.org/10.1177/0269881119832753.
Pełny tekst źródłaChen, Lin, Jinchi Zhou, Zifeng Zhao, Yuhan Zhu, Jinliang Xing, Jiaze An i Xu Guo. "Low Expression of Phosphodiesterase 2 (PDE2A) Promotes the Progression by Regulating Mitochondrial Morphology and ATP Content and Predicts Poor Prognosis in Hepatocellular Carcinoma". Cells 12, nr 1 (23.12.2022): 68. http://dx.doi.org/10.3390/cells12010068.
Pełny tekst źródłaBarbagallo, Federica, Valentina Rotilio, Maria Rita Assenza, Salvatore Aguanno, Tiziana Orsini, Sabrina Putti, Andrea M. Isidori i in. "PDE2A Is Indispensable for Mouse Liver Development and Hematopoiesis". International Journal of Molecular Sciences 21, nr 8 (21.04.2020): 2902. http://dx.doi.org/10.3390/ijms21082902.
Pełny tekst źródłaMatthiesen, Karina, i Jacob Nielsen. "Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity". Biochemical Journal 423, nr 3 (12.10.2009): 401–9. http://dx.doi.org/10.1042/bj20090982.
Pełny tekst źródłaRitawidya, Ludwig, Briel, Brust i Scheunemann. "Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[e]imidazo[2,1-c][1,2,4]triazines as Phosphodiesterase 2A Inhibitors". Molecules 24, nr 15 (31.07.2019): 2791. http://dx.doi.org/10.3390/molecules24152791.
Pełny tekst źródłaRentsendorj, Otgonchimeg, Mahendra Damarla, Neil R. Aggarwal, Ji-Young Choi, Laura Johnston, Franco R. D'Alessio, Michael T. Crow i David B. Pearse. "Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury". American Journal of Physiology-Lung Cellular and Molecular Physiology 301, nr 2 (sierpień 2011): L161—L170. http://dx.doi.org/10.1152/ajplung.00073.2011.
Pełny tekst źródłaJiang, Lei, i Shenghu Yan. "Prokaryotic Expression, Purification and Activity Detection of Phosphodiesterase 2A Protein". Journal of Biology and Life Science 11, nr 2 (16.04.2020): 1. http://dx.doi.org/10.5296/jbls.v11i2.16650.
Pełny tekst źródłaKubacka, Monika, Szczepan Mogilski, Marek Bednarski, Krzysztof Pociecha, Artur Świerczek, Noemi Nicosia, Jakub Schabikowski i in. "Antiplatelet Effects of Selected Xanthine-Based Adenosine A2A and A2B Receptor Antagonists Determined in Rat Blood". International Journal of Molecular Sciences 24, nr 17 (29.08.2023): 13378. http://dx.doi.org/10.3390/ijms241713378.
Pełny tekst źródłaWenzel, Barbara, Stefan R. Fritzsche, Magali Toussaint, Detlef Briel, Klaus Kopka, Peter Brust, Matthias Scheunemann i Winnie Deuther-Conrad. "Radiosynthesis and Preclinical Evaluation of an 18F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A)". Pharmaceuticals 15, nr 10 (15.10.2022): 1272. http://dx.doi.org/10.3390/ph15101272.
Pełny tekst źródłaKallenborn-Gerhardt, Wiebke, Ruirui Lu, Aaron Bothe, Dominique Thomas, Jessica Schlaudraff, Jana E. Lorenz, Nancy Lippold i in. "Phosphodiesterase 2A Localized in the Spinal Cord Contributes to Inflammatory Pain Processing". Anesthesiology 121, nr 2 (1.08.2014): 372–82. http://dx.doi.org/10.1097/aln.0000000000000270.
Pełny tekst źródłaMaurin, Thomas, Francesca Melancia, Marielle Jarjat, Liliana Castro, Lara Costa, Sébastien Delhaye, Anouar Khayachi i in. "Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome". Cerebral Cortex 29, nr 8 (23.08.2018): 3241–52. http://dx.doi.org/10.1093/cercor/bhy192.
Pełny tekst źródłaXu, Ying, Jianchun Pan, Ling Chen, Chong Zhang, Jiao Sun, Jianxin Li, Linda Nguyen, Neetu Nair, Hanting Zhang i James M. O'Donnell. "Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway". International Journal of Neuropsychopharmacology 16, nr 4 (1.05.2013): 835–47. http://dx.doi.org/10.1017/s146114571200065x.
Pełny tekst źródłaRassi-Cruz, Marcela, Andrea G. Maria, Fabio R. Faucz, Edra London, Leticia A. P. Vilela, Lucas S. Santana, Anna Flavia F. Benedetti i in. "Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism". Endocrine-Related Cancer 28, nr 1 (styczeń 2021): 1–13. http://dx.doi.org/10.1530/erc-20-0384.
Pełny tekst źródłaNakashima, Kosuke, i Hideki Matsui. "A Novel Inhibition Modality for Phosphodiesterase 2A". SLAS DISCOVERY: Advancing the Science of Drug Discovery 25, nr 5 (28.04.2020): 498–505. http://dx.doi.org/10.1177/2472555220913241.
Pełny tekst źródłaLi, Dan, Kun Liu, Harvey Davis, Calum Robertson, Oliver C. Neely, Adib Tarafdar, Ni Li, Konstantinos Lefkimmiatis, Manuela Zaccolo i David J. Paterson. "Abnormal Cyclic Nucleotide Signaling at the Outer Mitochondrial Membrane In Sympathetic Neurons During the Early Stages of Hypertension". Hypertension 79, nr 7 (lipiec 2022): 1374–84. http://dx.doi.org/10.1161/hypertensionaha.121.18882.
Pełny tekst źródłaRitawidya, Wenzel, Teodoro, Toussaint, Kranz, Deuther-Conrad, Dukic-Stefanovic, Ludwig, Scheunemann i Brust. "Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography". Molecules 24, nr 22 (15.11.2019): 4149. http://dx.doi.org/10.3390/molecules24224149.
Pełny tekst źródłaGong, Wei, Lei Yang, Yuanyuan Wang, Jianfeng Xian, Fuman Qiu, Li Liu, Mingzhu Lin, Yingyi Feng, Yifeng Zhou i Jiachun Lu. "Analysis of Survival-Related lncRNA Landscape Identifies A Role for LINC01537 in Energy Metabolism and Lung Cancer Progression". International Journal of Molecular Sciences 20, nr 15 (1.08.2019): 3713. http://dx.doi.org/10.3390/ijms20153713.
Pełny tekst źródłaLu, Jia Yang, i Marion B. Sewer. "p54nrb/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation". Molecular and Cellular Biology 35, nr 7 (20.01.2015): 1223–37. http://dx.doi.org/10.1128/mcb.00993-14.
Pełny tekst źródłaKeefer, Christopher E., i George Chang. "The use of matched molecular series networks for cross target structure activity relationship translation and potency prediction". MedChemComm 8, nr 11 (2017): 2067–78. http://dx.doi.org/10.1039/c7md00465f.
Pełny tekst źródłaTanaka, Saori, Rina Tanaka, Saeko Harada, Yuka Kohda, Hitoshi Matsumura, Chikao Shimamoto, Yukinori Sawabe i in. "A PKG inhibitor increases Ca2+-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition". American Journal of Physiology-Gastrointestinal and Liver Physiology 304, nr 9 (1.05.2013): G773—G780. http://dx.doi.org/10.1152/ajpgi.00281.2012.
Pełny tekst źródłaDing, Hao, Xiao-Xing Xiong, Guan-Lan Fan, Yue-Xiong Yi, Yu-Rou Chen, Jing-Tao Wang i Wei Zhang. "The New Biomarker for Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (CESC) Based on Public Database Mining". BioMed Research International 2020 (13.04.2020): 1–9. http://dx.doi.org/10.1155/2020/5478574.
Pełny tekst źródłaRusswurm, Corina, Georg Zoidl, Doris Koesling i Michael Russwurm. "Dual Acylation of PDE2A Splice Variant 3". Journal of Biological Chemistry 284, nr 38 (24.07.2009): 25782–90. http://dx.doi.org/10.1074/jbc.m109.017194.
Pełny tekst źródłaWang, Jianjie, Susan Bingaman i Virginia H. Huxley. "Intrinsic sex-specific differences in microvascular endothelial cell phosphodiesterases". American Journal of Physiology-Heart and Circulatory Physiology 298, nr 4 (kwiecień 2010): H1146—H1154. http://dx.doi.org/10.1152/ajpheart.00252.2009.
Pełny tekst źródłaSchmidt, Eric P., Mahendra Damarla, Otgonchimeg Rentsendorj, Laura E. Servinsky, Bing Zhu, Aigul Moldobaeva, Alfredo Gonzalez, Paul M. Hassoun i David B. Pearse. "Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice". American Journal of Physiology-Lung Cellular and Molecular Physiology 295, nr 6 (grudzień 2008): L1056—L1065. http://dx.doi.org/10.1152/ajplung.90329.2008.
Pełny tekst źródłaWang, Junnan, Mingyi Wu, Xiaowen Lin, Yun Li i Zhijian Fu. "Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-κB/p65 Signaling in Chronic Radiculitis Rats". Pain Research and Management 2018 (13.12.2018): 1–8. http://dx.doi.org/10.1155/2018/5192814.
Pełny tekst źródłaDurand, Julien, Antoine Lampron, Tania L. Mazzuco, Audrey Chapman i Isabelle Bourdeau. "Characterization of Differential Gene Expression in Adrenocortical Tumors Harboring β-Catenin (CTNNB1) Mutations". Journal of Clinical Endocrinology & Metabolism 96, nr 7 (1.07.2011): E1206—E1211. http://dx.doi.org/10.1210/jc.2010-2143.
Pełny tekst źródłaFryknäs, Mårten, Linda Rickardson, Malin Wickström, Sumeer Dhar, Henrik Lövborg, Joachim Gullbo, Peter Nygren, Mats G. Gustafsson, Anders Isaksson i Rolf Larsson. "Phenotype-Based Screening of Mechanistically Annotated Compounds in Combination with Gene Expression and Pathway Analysis Identifies Candidate Drug Targets in a Human Squamous Carcinoma Cell Model". Journal of Biomolecular Screening 11, nr 5 (28.04.2006): 457–68. http://dx.doi.org/10.1177/1087057106288048.
Pełny tekst źródłaJuilfs, D. M., W. K. Sonnenburg, S. Seraji, H.-I. Fülle, D. L. Garbers, M. D. Houslay i J. A. Beavo. "IDENTIFICATION OF A NEW PDE2A ISOFORM AND EXPRESSION OF PDE2 IN A SUBSET OF OLFACTORY NEURONS & GASTROINTESTINAL CELLS". Biochemical Society Transactions 24, nr 4 (1.11.1996): 624S. http://dx.doi.org/10.1042/bst024624s.
Pełny tekst źródłaMontoya-Durango, Diego, Mary Nancy Walter, Walter Rodriguez, Yali Wang, Julia H. Chariker, Eric C. Rouchka, Claudio Maldonado, Shirish Barve, Craig J. McClain i Leila Gobejishvili. "Dysregulated Cyclic Nucleotide Metabolism in Alcohol-Associated Steatohepatitis: Implications for Novel Targeted Therapies". Biology 12, nr 10 (10.10.2023): 1321. http://dx.doi.org/10.3390/biology12101321.
Pełny tekst źródłaPetersen, Tonny Studsgaard, Martin Stahlhut i Claus Yding Andersen. "Phosphodiesterases in the rat ovary: effect of cAMP in primordial follicles". REPRODUCTION 150, nr 1 (lipiec 2015): 11–20. http://dx.doi.org/10.1530/rep-14-0436.
Pełny tekst źródłaMa, Y. S., Y. H. Xie, D. Ma, J. J. Zhang i H. J. Liu. "Shear stress-induced MMP1 and PDE2A expressions in coronary atherosclerosis". Bratislava Medical Journal 122, nr 04 (2021): 287–92. http://dx.doi.org/10.4149/bll_2021_048.
Pełny tekst źródłaDoummar, Diane, Christel Dentel, Romane Lyautey, Julia Metreau, Boris Keren, Nathalie Drouot, Ludivine Malherbe i in. "Biallelic PDE2A variants: a new cause of syndromic paroxysmal dyskinesia". European Journal of Human Genetics 28, nr 10 (28.05.2020): 1403–13. http://dx.doi.org/10.1038/s41431-020-0641-9.
Pełny tekst źródłaAdderley, Shaquria P., Eileen A. Dufaux, Meera Sridharan, Elizabeth A. Bowles, Madelyn S. Hanson, Alan H. Stephenson, Mary L. Ellsworth i Randy S. Sprague. "Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans". American Journal of Physiology-Heart and Circulatory Physiology 296, nr 5 (maj 2009): H1617—H1624. http://dx.doi.org/10.1152/ajpheart.01226.2008.
Pełny tekst źródłaTrabanco, Andrés A., Peter Buijnsters i Frederik J. R. Rombouts. "Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present)". Expert Opinion on Therapeutic Patents 26, nr 8 (30.06.2016): 933–46. http://dx.doi.org/10.1080/13543776.2016.1203902.
Pełny tekst źródłaFarmer, Reagan, Steven D. Burbano, Neema S. Patel, Angelo Sarmiento, Abigail J. Smith i Michy P. Kelly. "Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease". Cellular Signalling 70 (czerwiec 2020): 109592. http://dx.doi.org/10.1016/j.cellsig.2020.109592.
Pełny tekst źródłaFernández-Fernández, Diego, Holger Rosenbrock i Katja S. Kroker. "Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus". Synapse 69, nr 10 (29.07.2015): 484–96. http://dx.doi.org/10.1002/syn.21840.
Pełny tekst źródłaZlobin, Alexander S., Natalia A. Volkova, Natalia A. Zinovieva, Baylar S. Iolchiev, Vugar A. Bagirov, Pavel M. Borodin, Tatiana I. Axenovich i Yakov A. Tsepilov. "Loci Associated with Negative Heterosis for Viability and Meat Productivity in Interspecific Sheep Hybrids". Animals 13, nr 1 (3.01.2023): 184. http://dx.doi.org/10.3390/ani13010184.
Pełny tekst źródłaNaganawa, M., R. N. Waterhouse, N. Nabulsi, S. F. Lin, D. Labaree, J. Ropchan, S. Tarabar i in. "First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430". Journal of Nuclear Medicine 57, nr 9 (21.04.2016): 1388–95. http://dx.doi.org/10.2967/jnumed.115.166850.
Pełny tekst źródłaHaidar, Zahraa, Nadine Jalkh, Sandra Corbani, Joelle Abou‐Ghoch, Ali Fawaz, Cybel Mehawej i Eliane Chouery. "A Homozygous Splicing Mutation in PDE2A in a Family With Atypical Rett Syndrome". Movement Disorders 35, nr 5 (20.03.2020): 896–99. http://dx.doi.org/10.1002/mds.28023.
Pełny tekst źródłaWunder, Frank, Mark Jean Gnoth, Andreas Geerts i Daniel Barufe. "A Novel PDE2A Reporter Cell Line: Characterization of the Cellular Activity of PDE Inhibitors". Molecular Pharmaceutics 6, nr 1 (2.12.2008): 326–36. http://dx.doi.org/10.1021/mp800127n.
Pełny tekst źródłaSalpietro, Vincenzo, Belen Perez-Dueñas, Kosuke Nakashima, Victoria San Antonio-Arce, Andreea Manole, Stephanie Efthymiou, Jana Vandrovcova i in. "A homozygous loss-of-function mutation in PDE2A associated to early-onset hereditary chorea". Movement Disorders 33, nr 3 (2.02.2018): 482–88. http://dx.doi.org/10.1002/mds.27286.
Pełny tekst źródłaClaire, Nicolas, Shittl Julia, Pertuiset Claire, Mehel Hind, Courilleau Delphine, Jullian Jean-Christophe, Cresteil Thierry i in. "0310 Assay development and high-throughput screening to identify PDE2A activators to treat heart failure". Archives of Cardiovascular Diseases Supplements 6 (kwiecień 2014): 43. http://dx.doi.org/10.1016/s1878-6480(14)71379-5.
Pełny tekst źródłaZhang, Zhao-Xiong, Qiang Han i Shu-Ye Liu. "Clinical significance of PDE2A in prognosis and immune infiltration in gastrointestinal cancer based on bioinformatics analysis". World Chinese Journal of Digestology 29, nr 18 (28.09.2021): 1055–63. http://dx.doi.org/10.11569/wcjd.v29.i18.1055.
Pełny tekst źródłaLi, San-Zhong, Kai-Xi Ren, Jing Zhao, Shuang Wu, Juan Li, Jian Zang, Zhou Fei i Jun-Long Zhao. "miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling". International Journal of Biological Sciences 17, nr 13 (2021): 3508–21. http://dx.doi.org/10.7150/ijbs.62858.
Pełny tekst źródłaSadhu, Krishna, Kelly Hensley, Vince A. Florio i Sharon L. Wolda. "Differential Expression of the Cyclic GMP-stimulated Phosphodiesterase PDE2A in Human Venous and Capillary Endothelial Cells". Journal of Histochemistry & Cytochemistry 47, nr 7 (lipiec 1999): 895–905. http://dx.doi.org/10.1177/002215549904700707.
Pełny tekst źródłaCann, M. J. "Sodium regulation of GAF domain function". Biochemical Society Transactions 35, nr 5 (25.10.2007): 1032–34. http://dx.doi.org/10.1042/bst0351032.
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