Rozprawy doktorskie na temat „PCMHE”
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Moore, Rick A. "Measuring the Impact of Recognized Patient-Centered Medical Homes (PCMH)". Thesis, Virginia Commonwealth University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=3746418.
Pełny tekst źródłaIt has been estimated that by 2020 nearly one-third of all Americans (almost 160 million people) will have at least one chronic disease to manage and the cost of health care will consume over 20 percent of the GDP. The Obama Administration responded to this pending crisis by passing the Patient Protection and Affordable Care Act (PPACA) in 2010. This major legislation aims to instill patient-centered, accountable care into the health care delivery system. Specifically, the United States government is on a mission to reduce the utilization of expensive inpatient care, while increasing access to primary care for all Americans, thereby lowering the total cost of health care.
Primary care practices organized around the principles of the patient-centered medical home (PCMH) can better manage their patients, especially their patients with chronic conditions; and become accountable for their care. In 2008, the National Committee for Quality Assurance (NCQA) released practice-level recognition standards based on the seven Joint Principles of the PCMH, to aid doctors seeking to transform their practices into effective patient-centered delivery systems.
The results of several published studies have touted the successes (e.g., reduced emergency department visits, reduced hospitalizations) of the PCMH model at individual practice sites. These localized successes demonstrated that the principle tenets of the PCMH model—care coordination, team-based care, population management—helped lower utilization of more expensive health care services within the specific practice settings evaluated. However, there has been no study to determine if these core tenets are having a broader impact on the health care delivery system within a community.
One hypothesized outcome of a health care system centered on the PCMH care model is better care coordination and more effective, whole-person care management across the continuum of health care; resulting in a more efficient system that can prevent avoidable hospitalizations.
This dissertation proposal seeks to understand if the increasing numbers (density) of recognized PCMH practices in communities affect avoidable hospitalizations related to ambulatory care sensitive conditions (ACSC), as measured by the AHRQ Composite Prevention Quality Indicators (PQI). The research has two purposes:
1. Establish constructs and hypotheses to measure the effect of the increasing numbers of NCQA-Recognized PCMH practices in communities (counties).
2. Using an outcomes-based measurement approach, investigate the relationship between growing densities of NCQA-Recognized PCMH practice doctors among all primary care doctors (PCD) in a community and the associated impact on the utilization of inpatient care, specifically related to ACSCs, as measured by the AHRQ Composite PQIs.
The research is quasi-experimental in design and is based on a retrospective (2008–2011) analysis of existing data from the NCQA PCMH program, the AHRQ Composite PQI and the Centers for Medicare & Medicaid Services (CMS) National Provider Identification (NPI) databases. Analysis will link NCQA-Recognized PCMH practices (independent variable), AHRQ Risk Adjusted Composite PQIs (dependent variable), and the CMS NPI (total PCDs) on Federal Information Processing Standard (FIPS) identifiers across 114 state and county-level geographical areas in Vermont and North Carolina. The research will inform the following hypotheses:
1. Does the research literature support the measurement construct proposed in this study?
2. Communities with concentrations of recognized PCMH practices among primary care practices will have lower risk-adjusted avoidable hospital admission rates.
3. The use of technology and care coordination will have a greater predictive correlation on risk-adjusted avoidable hospital admission rates than other PCMH capabilities.
Moore, Rick. "Measuring the Impact of Recognized Patient-Centered Medical Homes (PCMH)". VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/4069.
Pełny tekst źródłaShinde, Nikhil Vijay. "A Study on the Impact of Patient Centered Medical Home (PCMH) Implementation on Nursing Work Practice". Thesis, North Dakota State University, 2012. https://hdl.handle.net/10365/26660.
Pełny tekst źródłaCulcuoglu, Mustafa U. "Reengineering Community Based Chronic Care Delivery Systems: Theory and Applications". University of Akron / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=akron1627573050496332.
Pełny tekst źródłaWegman, Kevin R. "Numerical Modeling of a Printed Circuit Heat Exchanger Based on Experimental Results from the High-Temperature Helium Test Facility". The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461266010.
Pełny tekst źródłaNix, Tanya J. "Evolution of Physician-Centric Business Models Under Patient Protection and Affordable Care Act". ScholarWorks, 2014. http://scholarworks.waldenu.edu/dissertations/123.
Pełny tekst źródłaMylavarapu, Sai K. "Development of Compact Heat Exchangers for Very High-Temperature Gas-Cooled Reactors". The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228150070.
Pełny tekst źródłaMylavarapu, Sai Kiran. "Design, Fabrication, Performance Testing, and Modeling of Diffusion Bonded Compact Heat Exchangers in a High-Temperature Helium Test Facility". The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1321996306.
Pełny tekst źródłaWatkins, Sydney L. "Patient-Centered Medical Homes and Parental Attention-Deficit Hyperactivity Disorder Medication Beliefs and Adherence". ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5044.
Pełny tekst źródłaFigley, Justin T. "Numerical Modeling and Performance Analysis of Printed Circuit Heat Exchanger for Very High-Temperature Reactors". The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1244036854.
Pełny tekst źródłaTanenbaum, Joseph Elias. "The Association of Health Care Delivery and Payment Innovations with Avoidable Hospitalizations". Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1530814492308274.
Pełny tekst źródłaChen, Minghui. "DESIGN, FABRICATION, TESTING, AND MODELING OF A HIGH-TEMPERATURE PRINTED CIRCUIT HEAT EXCHANGER". The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1431072434.
Pełny tekst źródłaRANA, SACHIN. "CFD SIMULATION OF SHELL AND TUBE HEAT EXCHANGER FILLED WITH PHASE CHANGE MATERIAL FOR SOLAR WATER HEATING SYSTEM". Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/20147.
Pełny tekst źródłaLahare, Pushpendra Bahadur Singh. "Analysis of Rectangular Channel Printed Circuit Heat Exchanger(PCHE)". Thesis, 2016. http://ethesis.nitrkl.ac.in/8225/1/2016_MT_214ME5330_Analysis_of_Rectangular.pdf.
Pełny tekst źródłaBernard, Alec Jordan. "Effects of Patient-Centered Medical Home model on primary care". Thesis, 2014. https://hdl.handle.net/2144/15354.
Pełny tekst źródłaPezeshki, Abdul Mohammad. "Enforcing dendritic cell vaccines by manipulating the MHC II antigen presentation pathway". Thèse, 2012. http://hdl.handle.net/1866/9140.
Pełny tekst źródłaDendritic cell peptide-based vaccines are the most common immunotherapy approach in cancer therapy. While, in principle, dendritic cells (DCs) could be loaded efficiently by exogenously added tumor peptides, their loading efficacy is severely reduced due to low number of peptide-receptive MHC II on cell surface. Most surface MHC II molecules are either occupied by endogenous peptides or are inactive due to a conformation that is not receptive for free peptides. In MHC II antigen presentation pathway, HLA-DM (DM) in acidic endosomal vesicles removes the self-peptides and grants a peptide receptive conformation to MHC II. Mutating of an intracellular sorting motif in DM, renders its accumulation on cell surface. We hypothesized that the mutant DM (DMY) is functional on cell surface and can generate peptide receptive MHC II on surface of DCs for exogenous peptide loading. By using an adenoviral vector that expresses DMY, we found that DMY is functional on surface of DCs. DMY supplied peptide receptive MHC II on surface of DCs and improved exogenous peptide loading. The improvement of peptide loading by DMY is both quantitative and qualitative. DMY improves helper T cell (Th) response in Th1 direction that favors anti-cancer immunity. The qualitative improvement of peptide loading extends to loading of superior conformational isomer (conformer) of peptide-MHC complexes. This superior conformer (type A) is the favourite type for vaccination approaches and DMY successfully edits peptide-MHC conformers on cell surface level by eliminating undesirable one (type B). Function of DM is regulated by HLA-DO (DO) and it is well accepted that in acidic pH of late endosomes, DO inhibits function of DM by preventing removal of class II associated invariant chain peptide (CLIP) from peptide binding groove of MHC II. My results indicate that DO overexpression, changes binding of peptide-dependent superantigens to MHC II molecules. Superantigens (SAgs) are small microbial proteins that bind out side peptide binding groove of MHC II. DO probably enhances binding of peptide-dependent SAgs by forcing the accumulation of CLIP on the cell surface of antigen presenting cells. DO also neutralizes Th2 polarization by CLIP. Collectively, these results indicate that DMY is a valuable tool for improvement of exogenous peptide loading in DCs vaccines. An unnoticed effect of DO on SAgs binding was also recognized. Further investigations are needed to clarify the mechanisms by which, DMY and DO influence Th polarization. This would provide a better understanding of antigen presentation pathway and its interaction with immune system.