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Williams, Caroline. "It's Not a Beauty Pageant!: An Examination of Leadership Development through Alaska Native Pageants". Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/293488.
Pełny tekst źródłaAndrade, José Costa de [UNESP]. "Perfil imunoistoquímico do carcinoma de Paget da mama". Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/103714.
Pełny tekst źródłaUniversidade Estadual Paulista (UNESP)
O objetivo deste trabalho foi estudar através do exame Imunoistoquimico, a correlação entre alguns fatores Anatomopatológicos (tipo histológico e grau nuclear) e alguns fatores biológicos (receptores hormonais de estrógeno e de progesterona, proteína c-erbB-2 e proteína p53, no carcinoma de Paget da mama, doença rara e especial. No período entre Janeiro de 1980 a Dezembro de 1998 foram tratados no Instituto Brasileiro de Controle do Câncer, 6.303 casos de câncer de mama, deste total 98 casos foram diagnosticados como carcinoma de Paget, cuja incidência foi de 1,55%. Estudamos retrospectivamente 60 casos, sendo que 38 deles foram excluídos da análise, devido a limitação e escassez da amostra no material disponível, a idade das pacientes variou entre 26 e 84 anos, com média de 55,4 anos, as informações clínicas e terapêuticas foram obtidas dos prontuários das pacientes considerando, idade na época do diagnóstico, tamanho do tumor quando palpável, estadiamento clínico, e o tipo de cirurgia realizada. As amostras de tecido mamário foram recuperadas dos arquivos do Departamento de Anatomia Patológica do I.B.C.C. / MATTOSINHO. Após a revisão histológica, realizada por dois patologistas os casos foram classificados em quatro grupos: Grupo A- Doença de Paget (forma pura) n = 09 Grupo B- Doença de Paget + neoplasia ductal “in situ”, n = 12 Grupo C- Doença de Paget, neoplasia ductal invasora, n = 30 Grupo D- Doença de Paget + neoplasia ductal “in situ”+ neoplasia ductal invasora, n = 09. Entre as variáveis anatomopatológicas, o grupo C prevaleceu com 30 casos (50%). O grau nuclear (GN-II) predominou com 45 casos (75%). Em relação as variáveis biológicas o receptor de estrógeno negativo predominou com 41 casos (68,3%), seguido pelo receptor de progesterona negativo com 40 casos (66,7%), podemos dizer que...
The objective of this paper was to study the immunohistochemical efects of Paget’s disease, a rare and special carcinoma of the breast, by correlating anatomopathological (histological and nuclear grade) and biological (estrogen and progesterone hormonal receptors, c-erbB-2 protein and p53 protein) factors. Between January 1980 and December 1998, 6303 cases of breast cancer were treated at the Brazilian Institute of Cancer Control; 98 of these were diagnosed with Paget’s carcinoma, an incidence of 1.55%. We retrospectively studied 60 of these cases; 38 were excluded due to lack of available sample material. Patient age varied between 26 and 84 years (mean 55.4), clinical and therapeutic information were obtained from patient’s medical records considering age at time of diagnosis, tumor size when palpable, clinical stage, and type of surgery performed. Samples of breast tissue were retrieved the Anatomical Pathology Department, I.B.C.C. / MATTOSINHO. After histological review, by two different pathologists, they were classified into four groups: Group A- Paget’s disease (pure form) n = 09 Group B- Paget’s disease + “in situ” duct neoplasia n = 12 Group C- Paget’s disease, invasive duct neoplasia n = 30 Group D- Paget’s disease + “in situ” duct neoplasia + invasive duct neoplasia n = 09.Invasive duct neoplasia was the most prevalent anatomopathological variable (Group C, n = 30, 50%). Nuclear grade (GNII) was found in 45 cases (75%). In relation to the biological variables, the negative estrogen receptor was predominant with 41 cases (68.3%), followed by the negative progesterone receptor with 40 cases (66.7%); this correlation had good concordance by the Kappa test. The c-erbB-2 protein was positive in 53 cases (88.3%) and p53 was negative in 47 cases (78.3%). From these results, we concluded that there was no statistical... (Complete abstract click electronic address below)
Lewis, Heidi D. ?UNAUTHORIZED. ""Speaking out of the dust" : religious reenactments with the specific iconic identity of place /". Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1478.pdf.
Pełny tekst źródłaAmilibia, Cabeza Emilio. "Caracterización de la hipoacusia en la enfermedad de Paget". Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/664352.
Pełny tekst źródłaIntroduction and objectives: Paget’s disease of bone (PDB) may lead to hearing loss. The present study is conducted with the aim of measuring, characterizing, determining the risk factors for hearing loss and analyse the possible relation of hearing loss with tomography findings in a group of subjects with PDB. Methods: An observational, transversal, case-control study was conducted, a cohort of 76 subjects diagnosed of Paget’s disease of bone (PDB) in the case group and a control group of 134 subjects were included. Clinical, demographic, audiometric and tomographic data (by means of a CT scan study) were analysed. Results: The comparative analysis between the subjects in the PDB group and the control group found that the case group showed higher hearing thresholds (39,51dB) comparing with the control group (37,28 dB) (p=0,069) and presented a greater rate of conductive hearing loss (22,76%) than the control group (12,05%) (p=0,0062). The study of risk factors for hearing loss found that skull involvement in bone scintigraphy, age and high blood pressure were risk factors for higher hearing impairment in PDB. The CT scan data showed that subjects in the PDB group had lower temporal bone density (Hounsfield Units, HU) comparing with the control group. It was also found that the otic capsule bone density in the PDB group correlated with both the air and bone conduction hearing thresholds (p<0,05) and that the finding of an air-bone gap in the audiogram correlated with Paget’s disease temporal bone involvement. Conclusions: − The 63,45% of subjects with Paget’s disease of bone (PDB) suffer hearing loss with a hearing threshold of 39,51dB on average. − The subjects with PDB showed a deeper hearing loss and a higher proportion of conductive type than the control group. − The patients with PDB and skull involvement presented a more severe hearing loss compared with the subjects without skull involvement. Skull involvement and age were found to be risk factors for hearing loss. − In the PDB group both the air and bone conduction hearing thresholds correlated with the otic capsule bone density.
Conesa, Mateos Arántzazu. "Caracterización clínica, epidemiológica y molecular de la enfermedad Ósea de Paget". Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/673198.
Pełny tekst źródłaLa enfermedad ósea de Paget (EOP) se caracteriza por ser un trastorno crónico y focal del remodelado óseo que conlleva a la aparición de complicaciones como deformidades óseas, artropatía por vecindad y fracturas. La EOP presenta una gran variabilidad en su distribución en función de la edad, género, etnia y área geográfica. Recientes estudios han descrito cambios seculares en cuanto a la prevalencia, incidencia y gravedad al diagnóstico de la EOP, mostrando una disminución en las últimas décadas. La EOP se considera actualmente una enfermedad multifactorial con participación de factores ambientales y genéticos. El gen que ha mostrado mayor susceptibilidad es el Sequestosoma1(SQSMT1), las mutaciones descritas en él no explicarían de forma completa la patogenia de la EOP. En la actualidad, son escasos los estudios acerca de variaciones genéticas en los genes TNFRSF11B y TNFRSF11A asociados a EOP clásica así como la existencia de interacciones genéticas entre ambos genes y el gen SQSMT1, que conduzca a un incremento de riesgo de EOP e incluso que influya en el fenotipo. Con la finalidad de investigar el patrón de comportamiento clínico-epidemiológico como genético de la EOP de nuestra población de baja prevalencia, nos planteamos los siguientes objetivos. Los objetivos se centraron en evaluar cambios en la evolución del porcentaje de nuevos diagnósticos de EOP durante el periodo 1970-2009 y describir en dichos pacientes diferencias en cuanto a la severidad al diagnóstico. Así como así como analizar la importancia de alteraciones moleculares en el gen SQSTM1 y la presencia de variaciones alélicas en los genes TNFRSF11B y TNFRSF11A, tanto en la susceptibilidad para el desarrollo de la EOP como la influencia en su fenotipo. Pacientes y Métodos: Estudio descriptivo ambispectivo observacional de pacientes procedentes del Hospital del Mar-Parc de Salut Mar (Barcelona), un área de baja prevalencia. Se incluyeron 393 pacientes, diagnosticados entre 1970 y 2009. En base al estudio molecular se llevó a cabo el genotipado de las 21 variantes polimórfica para el estudio los genes TNFRSF11B y TNFRSF11A, así como la secuenciación del gen SQSTM1 en una población de 200 pacientes afectos de EOP y 200 controles hipernormales. Resultados: En el estudio se observa un descenso progresivo del porcentaje de nuevos diagnósticos de EOP en relación a la población de referencia, entre 1994 y 2009, más marcado en el grupo de ≥ de 65 años. Asimismo, se ha constatado que los pacientes afectos de EOP presentan una disminución en la actividad biológica de la enfermedad, una menor extensión de la enfermedad y una mayor edad de presentación al diagnóstico, en función del año de nacimiento y año del diagnóstico. En contraposición, se ha observado mayor severidad en el momento del diagnóstico en los pacientes con edades al diagnóstico de <45 años y ≥75 años. Se han identificado 5 factores independientes de mal pronóstico al diagnóstico, que van a favorecer peores desenlaces. Por lo que podemos concluir, que en el momento de diagnóstico de EOP, la expresión de la enfermedad es menos severa y acontece de forma más tardía. Los resultados del estudio molecular destacan la asociación significativa entre los SNPs rs3018362 y rs1805034 del gen TNFRSF11A y rs11573871 del gen TNFRSF11B con el incremento de riesgo a desarrollar EOP así como la influencia en su fenotipo. Asimismo se observó que la presencia del alelo T en el polimorfismo rs6567274 del gen TNFRSF11A se asoció con una disminución de riesgo a desarrollar la EOP, así como a un fenotipo más leve. En el estudio molecular del gen SQSTM1 se identificaron seis variantes genéticas "missense" de nueva descripción, asociadas todas ellas a una mayor susceptibilidad en el desarrollo de la EOP.
Paget’s Disease of Bone (PDB) is characterized by a chronic and focal disorder of bone remodeling that leads to the appearance of complications as bone deformities, osteoarthritis and fractures. The PDB presents a great variability in its distribution depending on the age, gender, ethnics and geographic area. Recent studies have described secular changes in the prevalence, incidence and severity at diagnosis of PDB, showing a decline in the last decades. PDB is currently considered a multifactorial disease involving environmental and genetic factors. The gene which has shown higher susceptibility is the Sequestosome-1 (SQSTM1), the mutations described in it would not be able to explain completely the PDB pathogenesis. Nowadays, there are few studies on genetic variations in the TNFRSF11B and TNFRSF11A genes associated with classic PDB, as well as the existence of genetic interactions between both genes and the SQSMT1 gene, leading to an increased risk of PDB or even influencing the phenotype. To investigate the pattern of clinical-epidemiological and genetic behavior of the PDB in our low prevalence population, we propose the following objectives. The objectives were focused on evaluating changes in the evolution of the percentage of new PDB diagnoses during the period 1970-2009 and to describing in those patients differences in terms of severity at diagnosis. As well as to analyze the importance of molecular alterations in the SQSTM1 gene and the presence of allelic variations in the TNFRSF11B and TNFRSF11A genes, both in the susceptibility for the development of PDB and its influence on the phenotype. Patients and Methods: Descriptive, ambispective observational study of patients from Hospital del Mar-Parc de Salut Mar (Barcelona), a low prevalence area. 393 patients, diagnosed between 1970 and 2009, were included. Based on the molecular study, the genotyping of the 21 polymorphic variants was carried out for the study of the TNFRSF11B and TNFRSF11A genes, as well as the sequencing of the SQSTM1 gene in a population of 200 PDB affected patients and 200 hypernormal controls. Results: The study observed a progressive decrease in the percentage of new PDB diagnoses in relation to the reference population, between 1994 and 2009, more marked in the group ≥65 years old group. Thereby, it has been confirmed that the PDB-affected patients show a decrease in the biological activity of the disease, a lower extension of the disease, and a higher age of presentation at diagnosis, depending on the year of birth and the year of diagnosis. In contrast, it has been observed higher severity at diagnosis in patients with ages at diagnosis <45 years and ≥75 years. Five independent factors of poor prognosis at diagnosis have been identified, which will favor worse outcomes. We can conclude, that at the time of diagnosis of PDB, the expression of the disease is less severe and occurs later. The results of the molecular study highlight the significant association between SNPs rs3018362 and rs1805034 of the TNFRSF11A gene and rs11573871 of the TNFRSF11B gene with the increased risk of developing PDB as well as the influence on its phenotype. Thereby, it was observed that the presence of the T allele in the polymorphism rs6567274 of the TNFRSF11A gene was associated with a decreased risk of developing PDB, as well as a milder phenotype. In the molecular study of the SQSTM1 gene, six newly described “missense” genetic variants were identified, all associated with greater susceptibility in the development of PDB.
Universitat Autònoma de Barcelona. Programa de Doctorat en Medicina
McManus, Stephen. "Regulation of osteoclast activation and autophagy through altered protein kinase pathways in Paget's disease of bone". Thèse, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/8960.
Pełny tekst źródłaAbstract : Paget’s disease of bone (PDB) is a skeletal disorder characterized by focal and disorganized increases in bone turnover. In PDB, osteoclasts are larger, more active, more numerous, and resistant to apoptotic stimuli. While no single root cause has been identified, mutations to the gene encoding the p62 protein, SQSTM1, have been described in a significant population of patients with PDB. Among these mutations, the P392L substitution is the most prevalent, and overexpression of p62P392L in osteoclasts generates at least a partial pagetic phenotype in vitro. Normally this protein mediates a number of cell functions, from control of NF-κB signaling to autophagy. In human osteoclasts, a multiprotein complex containing p62 and protein kinases PKCζ and PDK1 (the principal kinase of Akt), form in response to stimulation by receptor activator of nuclear factor kappa-B ligand (RANKL), the principal osteoclastogenic-signaling cytokine. We found that PKCζ is involved in RANKL-induced activation of NF-κB, and that it contributed to a basal activation of NF-κB observed in p62P392L mutants. This may be regulated in part by a PKCζ dependent increase in p65 phosphorylation at Ser536 which we characterized, independent of IκB. This could represent one alternative pathway by which mutant p62 leads to increased NF-κB activation. We observed increased basal phosphorylation of survival regulators ERK and Akt in PDB that was reduced upon PDK1 inhibition. The activity of 4EBP1 and Raptor, associated with mTOR activity, were also altered in pagetic osteoclasts and regulated by PDK1 inhibition. We then identified autophagic defects common to pagetic osteoclasts; with higher basal levels of LC3II (associated with autophagic structures), regardless of p62 mutation, and reduced sensitivity to autophagy induction in PDB. These results suggest an accumulation of non-degradative autophagosomes. Inhibition of PDK1 not only induced apoptosis in PDB and controls, but significantly reduced resorption in PDB, and with regards to autophagy, PDK1 inhibition was more potent in PDB than in controls. Therefore PDK1/Akt signaling represents an important checkpoint to PDB osteoclast activation. In sum, these results demonstrate the importance of several p62-associated kinases in the over-activation of pagetic osteoclasts, through increased survival and altered signaling. As p62 mutations alone do not account for most cases of PDB, the characterization of these pathways may identify a common factor linking pagetic osteoclasts. Therefore these studies represent a novel approach to osteoclast apoptosis, activation, and autophagy associated with PDB.
Bounahai, Najib. "Moors in Elizabethan/Jacobean entertainments : race, performance and politics /". Thesis, Connect to Dissertations & Theses @ Tufts University, 2001.
Znajdź pełny tekst źródłaAdviser: Barbara Freedman. Submitted to the Dept. of Drama. Includes bibliographical references (leaves 191-207). Access restricted to members of the Tufts University community. Also available via the World Wide Web;
Yoshino, Ayako. "The Edwardian historical pageant". Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614849.
Pełny tekst źródłaNazari, Shekeba. "Maladie de Paget : résistance à l'apoptose et défaut de l'autophagie". Mémoire, Université de Sherbrooke, 2017. http://hdl.handle.net/11143/11869.
Pełny tekst źródłaAbstract : Paget's disease is an osteopathy characterized by a multifocal increase in bone remodeling, which begins with excessive bone resorption followed by increased bone formation. Osteoclasts "OCs" were incriminated in the initiation of the pagetic process. Pagetic OCs are characterized by a resistance to apoptosis, and abnormalities in the process of autophagy “in particular induction defect”. In order to define whether these two characteristics were linked, we hypothesized the role of Bcl2-Beclin1 complexes. Beclin-1 is an autophagy-inducing protein that can bind anti-apoptotic proteins of the Bcl-2 family; Bcl-2 then inhibits Beclin-1 "and thus the induction of autophagy" while retaining its anti-apoptotic functions. To study the impact of Bcl2 expression on autophagy in human OCs, we used an in vitro differentiation model that uses monocytes, which are derived from umbilical cord blood and grown in the presence of RANKL and MCSF for 21 days. These conditions make it possible to obtain multinucleated cells with an osteoclastic phenotype. To increase the expression of Bcl-2 in OCs and analyze its impact on autophagy due to its interaction with Beclin-1, cultures were stimulated with TNFα or RANKL in order to induce NF-κB activation. The expression of Beclin1 and Bcl2 was confirmed by immunoblotting of Ocs cell lysates. Autophagy was induced in cultures carried out under stringent conditions "nutriment-deprived mediun", but we did not observe any variation in the expression of Bcl2 or Beclin 1 according to the culture conditions or TNFα or RANKL stimulation. TNFα significantly stimulated the activation of NF-κB in HEK cells but not in OCs. However, whatever the conditions, results from immunoprecipitaion experiments did not reveal any association between Beclin1 and Bcl2. On the other hand, the classic interaction partner of Beclin1, PI3K type III, was associated with Beclin1. In conclusion, our work did not allow us to demonstrate the formation of Beclin1 / Bcl2 complexes and the relationship between apoptosis and autophagy, partly because of the complexity of the model "multiple effects of NF-κB and TNFα". Our initial hypothesis should thereby be re-evaluated using a more appropriate methodology. On the other hand, the different techniques are now ready for further study.
Beckham, Kathryn Ann. "'The Gate City' artistry and identity in an American historical pageant (Nebraska) /". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 14.18 Mb., 74 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:1435838.
Pełny tekst źródłaThompson, Elisabeth Blumer. "Trailer park royalty Southern child beauty pageants, girlhood and power /". Click here to access dissertation, 2007. http://www.georgiasouthern.edu/etd/archive/spring2007/elisabeth_b_thompson/thompson_elisabeth_b_200708_edd.pdf.
Pełny tekst źródła"A dissertation submitted to the Graduate Faculty of Georgia Southern University in partial fulfillment of the requirements for the degree Doctor of Education." Curriculum Studies, under the direction of William M. Reynolds. ETD. Electronic version approved: December 2007. Includes bibliographical references (p. 208-228) and appendices.
Gapps, Stephen. "Performing the past : a cultural history of historical reenactments". Online version, 2002. http://hdl.handle.net/2100/625.
Pełny tekst źródłaThe reenactment of the past itself has a history. This thesis analyses self-styled 'historical reenactors' in the West and traces the history of the broader phenomenon of historical reenactment in the Australian context from the late nineteenth century to the present. The historical section focuses on several events significant in Australian cultural memory that have been reenacted over time. Historical parades, pageants and reenactments dramatically narrate culturally specific historical sensibilities and demonstrate inter and cross cultural exchanges of historical consciousness. I contend such performances have had a significant position in the formation of popular history since the late nineteenth century and that there is a continuity of conventions in performing the past. I have addressed the position of reenactments as part of a constant interest in the status and power of history in, and for, popular culture. I have shown how a form of history that operated for the public was transformed into a form of history operated by the public in a struggle for authority over the form and content of history. Historical reenactments have been useful avenues for elites to create didactic spectacular history that have also offered the opportunity for marginalised groups to make social and political gains through their participation in the making of public history. Considering the significance of reenactments in the formation of a distinctly Australian public history, they have received little attention from historians. As ephemera, reenactments sit awkwardly in the explanatory frameworks regularly used by historians. Using methodologies from a range of academic disciplines such as performance studies, anthropology and cultural studies, this thesis documents and interrogates the specific form of historical reenactment. In the sections of this thesis that analyse contemporary historical reenactments, I use my own experience as an historical reenactor of more than ten years in an ethnographic approach that reflects on the pleasures, promises and problems 'dressing up as if from the past' offers. In this history I draw continuities between past reenactments and present practices that assist in understanding historical reenactment as a specific cultural form. This thesis contends that reenactments over time have been characterised by three main elements: a collapsing of past and present, an avenue for a 'connectedness' with the past through a sensual experience, and an essential relationship with I authenticity.'
Lucas, Gavin J. A. "Genetics of Paget's disease of bone". Thesis, University of Aberdeen, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430978.
Pełny tekst źródłaHocking, Lynne J. "Genetics of Paget's disease of bone". Thesis, University of Aberdeen, 2002. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU160239.
Pełny tekst źródłaGood, David Andrew, i n/a. "Genetic Loci for Paget's Disease of Bone". Griffith University. School of Biomolecular and Biomedical Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040319.125358.
Pełny tekst źródłaNajat, Dereen. "SQSTM1 mutations and Paget's disease of bone". Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/11118/.
Pełny tekst źródłaBirch, Mark Andrew. "Investigations of bone cells in Paget's disease". Thesis, University of Liverpool, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333632.
Pełny tekst źródłaGood, David Andrew. "Genetic Loci for Paget's Disease of Bone". Thesis, Griffith University, 2003. http://hdl.handle.net/10072/365759.
Pełny tekst źródłaThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
Full Text
Hale, Annette Julie. "The characterisation of the Pagetic osteoclast". Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359919.
Pełny tekst źródłaDraheim, Dirk. "Typed server pages". [S.l. : s.n.], 2002. http://www.diss.fu-berlin.de/2003/57/index.html.
Pełny tekst źródłaTörnell, Mattias. "Richard Pages Sound". Thesis, Linnéuniversitetet, Institutionen för musik och bild (MB), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-27178.
Pełny tekst źródłaKumar, Rati. "Islam & Christianity a qualitative analysis of the online communication strategies used by religious groups to promote their ideologies /". [Gainesville, Fla.? : s.n.], 2008. http://understandingreligion.vndv.com/finalsite/pages/homepage/.
Pełny tekst źródłaBarrell, Howard. "Conscripts to their age African National Congress operational strategy, 1976-1986 /". Thesis, [Pretoria, South Africa : South African History Online], 1993. http://www.sahistory.org.za/pages/sources/barrel%5Fthesis/.
Pełny tekst źródłaTitle from introductory page (SAHO website, viewed July 28, 2005). Includes bibliographical references. HTML version of the print thesis.
Williams, Heather A. "Miss Homegrown the performance of food, festival, and femininity in local queen pageants /". Bowling Green, Ohio : Bowling Green State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1245452161.
Pełny tekst źródłaSubiñà, i. Coll Enric 1970. "El Maresme medieval. Exemples concrets de comunitats pageses". Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/401438.
Pełny tekst źródłaThe purpose of this thesis/research is to have a vision of the residents’ routine life in Mataró, Argentona and Òrrius, from mid XIV century till end of XV Century. This research is based in three fundamental facts to explain it: the manor, the population and the society. The demography has allowed us to see how Mataró was rapidly increasing its population against Argentona and Òrrius where it was declining. We have documented a high amount of territorial manors, being the jurisdictional manors in hands of their own castles. During the second half of XIV Century, the "remences" (servile people) represented half of the territory’s population. The manor implied some sort of rights and for the payment of taxes. The census where paid mainly in kind, although, while years were passing by, this will turn into money. Among the manors rights we emphasize the mills and iron mongeries, but also the scribes, stoves, markets and meat shops. All the territory was populated, mainly with farms. Mataró since the second half of XVI Century, have experimented an urban growth surrounding the market square where it was located the water well, the communal stoves, the meat shops and the arcade stores. Some of the facts we have been able to document properly are the abandoned farms, which started on the XIII Century. Many farmers have taken the farms to their heritage buying them either through establishment which were always under advantageous conditions for the sirs. The farms usually have lands under the dominion of various manors and were fragmented around the territory, sometimes without territorial continuity. The last chapter is mainly based on the family, in two important facts: marriage and death. We've studied the dowry and the territorial origins of the consorts and spouses. Thanks to the will/testament we know about the religious environment of the testators being able to going deeper among the churches and chapels of each parish and acknowledge the altars. The family legacy is taking us closer to the family core. This research ends explaining the role and the relevance of the male heirs and the 'pubillas' (the female version of the male heir, the eldest daughter) and with the last review: the universal heir.
Heltsley, Martha. "Beauty Pageant Mothers: Demographics, Motivations, and Family Structure". TopSCHOLAR®, 1998. http://digitalcommons.wku.edu/theses/311.
Pełny tekst źródłaNuman, Mohamed. "Gene-environment interaction in Paget's disease of bone". Master's thesis, Université Laval, 2017. http://hdl.handle.net/20.500.11794/27518.
Pełny tekst źródłaPaget's disease of bone (PDB) is a metabolic bone disease. Although genetic factors play an important role in the pathogenesis of PDB, environmental factors such as rural residence and the exposure to wood heating was associated with PDB. In order to study the role of outdoor and indoor air pollutants on PDB, we performed a survey in 140 French-Canadian patients with PDB and 113 healthy controls. The survey covered the outdoor air pollution such as the residence near a highway, a bus station, a train or an airport or a gas station, and indoor air pollutants by focusing on heating fuels (carbon, wood, oil) and exposure to tobacco smoke. In a subgroup of patients, urinary concentration of 17 heavy metals and 11 polycyclic aromatic hydrocarbons was measured by mass spectrometry. In light of what we knew from the survey and urinary assays, we identified certain toxics that could be risk factors for PDB. To explore the in vitro effects of these toxics on osteoclasts in PDB, we conducted in vitro monocytes differentiation from peripheral blood of more than 40 participants, patients, healthy carriers of p.Pro392Leu mutation, and healthy controls, which osteoclasts were treated with or without the identified toxic. The morphology of osteoclasts, the percentage of bone resorption, gene expression level, and cellular oxidative stress levels were assayed. The results showed an inhibitory effect of cigarette smoke condensate and heavy metals on morphology and function of patients’ osteoclasts. Further, high levels of oxidative stress in patients’ osteoclasts were observed, and a heterogenic profile of heavy metals effect on gene expression was identified.
Billah, Ahmed Mohammed El-Motaz. "Markers of bone turnover in health and disease". Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295769.
Pełny tekst źródłaGinty, Andrew Francis. "A study of cellular proliferation, plasminogen activator activity and cytokine expression in human osteoblasts and tumour cells". Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261975.
Pełny tekst źródłaAhlsén, Emely. "Open spaces - blank pages". Thesis, Konstfack, Ädellab/Metallformgivning, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-3227.
Pełny tekst źródłaMotlow, Elizabeth Handley. "Pages from my library /". Online version of thesis, 1985. http://hdl.handle.net/1850/8754.
Pełny tekst źródłaSelf, Lance. "APPLYING INTERACTIVE WEB PAGES". International Foundation for Telemetering, 2001. http://hdl.handle.net/10150/607689.
Pełny tekst źródłaVisitors to web pages are, in most cases, restricted to viewing information the page designer has anticipated they will be interested in viewing. Many times this is adequate, but there are instances where the visitor wants the information they view to be based on selections they choose. The Air Force Research Laboratory (AFRL) Space Vehicles Directorate anticipates selected customers will have a need to view very large data sets that vary from the satellite payload to the satellite state of health1, and will require controlling what they view in an “ad hoc” manner. In response, AFRL is using Java Server Pages developed within the data center to bring interactive and dynamic web page content to these customers.
Austin, Jill Hemming. "Performing the past| Two pageant traditions in Nauvoo, Illinois". Thesis, Indiana University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3715827.
Pełny tekst źródłaJill Hemming Austin PERFORMING THE PAST: TWO PAGEANT TRADITIONS IN NAUVOO, ILLINOIS The founders of American historical pageantry were keenly interested in the social effect of pageant performance on audience and participants. Their vision for social transformation through performance endures into the present day with those who continue to promulgate the form. Examining two enduring pageant traditions in Nauvoo, Illinois affords a better understanding of how the formal features of outdoor historical pageant production and the social relations that underlie them are still potentially powerful for those who participate in their production and performance. This dissertation encourages serious study of pageants as a unique performance form particularly attuned to the tasks of building continuities and tradition, the reinforcement of group sentiment, and the propitiation of group myth. Nauvoo, Illinois is a historically contested site boasting two historical pageants dedicated to the portrayal of the Nauvoo story: The Grape Festival Pageant and The Nauvoo Pageant. Christened ?Nauvoo? by Mormon [LDS] refugees in the mid-19th century, the thriving city?s overwhelming social discord drove the Mormons west, and the town was resettled and reclaimed by new seekers and settlers. The legendary quality of Nauvoo continued to grow in the Mormon imagination, eventually leading to a reclamation process including heritage development. Competing claims on local history has led to a heightened historical consciousness among townsfolk and ongoing public presentation from multiple perspectives. The two pageants are cultural displays that influence this ongoing social process. Both derive from distinct traditions--the local drama squarely planted in American historical pageantry and the Mormon-sponsored pageant deriving from LDS social and religious culture. Historical pageants have some unique formal features that make them particularly interesting to folklorists. They depend heavily on sacred localities, tradition, legend, and large-group participation for their success. The story told gains power from familiarity and reinforcement of cherished group values. However, changing tastes and sensibilities have challenged the survival of pageants as a relevant cultural form into the present. Drawing on interviews, field observation, and historical research, the contemporary context of the town and its two performances is fleshed out in the voices of four individuals who have participated in the pageants.
Taggart, Frances Margaret. "The epidemiology of Paget's disease of bone in Europe". Thesis, University of Southampton, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328623.
Pełny tekst źródłaRios, Visconti Micaela. "Genetic and environmental determinants of Paget's disease of bone". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/20421.
Pełny tekst źródłaWang, Yi. "Hierarchhical classification of web pages". Thesis, University of Macau, 2008. http://umaclib3.umac.mo/record=b1943013.
Pełny tekst źródłaGragg, Joan Elisabeth. "Seeing the funny side: focusing on Cook Islands humour in the experience of the religious pageant Nuku". AUT University, 2010. http://hdl.handle.net/10292/908.
Pełny tekst źródłaBell, Lynne Sevon. "Post mortem microstructural change to the skeleton". Thesis, University College London (University of London), 1995. http://discovery.ucl.ac.uk/1317796/.
Pełny tekst źródłaBaldwin, Elizabeth Marian Syson. "#The worship of the cyte and the welthe of the craft' : the Cappers of Coventry and their involvement in the civic drama 1494-1591". Thesis, University of Leeds, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293687.
Pełny tekst źródłaAndrade, José Costa de. "Perfil imunoistoquímico do carcinoma de Paget da mama /". Botucatu : [s.n.], 2004. http://hdl.handle.net/11449/103714.
Pełny tekst źródłaResumo: O objetivo deste trabalho foi estudar através do exame Imunoistoquimico, a correlação entre alguns fatores Anatomopatológicos (tipo histológico e grau nuclear) e alguns fatores biológicos (receptores hormonais de estrógeno e de progesterona, proteína c-erbB-2 e proteína p53, no carcinoma de Paget da mama, doença rara e especial. No período entre Janeiro de 1980 a Dezembro de 1998 foram tratados no Instituto Brasileiro de Controle do Câncer, 6.303 casos de câncer de mama, deste total 98 casos foram diagnosticados como carcinoma de Paget, cuja incidência foi de 1,55%. Estudamos retrospectivamente 60 casos, sendo que 38 deles foram excluídos da análise, devido a limitação e escassez da amostra no material disponível, a idade das pacientes variou entre 26 e 84 anos, com média de 55,4 anos, as informações clínicas e terapêuticas foram obtidas dos prontuários das pacientes considerando, idade na época do diagnóstico, tamanho do tumor quando palpável, estadiamento clínico, e o tipo de cirurgia realizada. As amostras de tecido mamário foram recuperadas dos arquivos do Departamento de Anatomia Patológica do I.B.C.C. / MATTOSINHO. Após a revisão histológica, realizada por dois patologistas os casos foram classificados em quatro grupos: Grupo A- Doença de Paget (forma pura) n = 09 Grupo B- Doença de Paget + neoplasia ductal "in situ", n = 12 Grupo C- Doença de Paget, neoplasia ductal invasora, n = 30 Grupo D- Doença de Paget + neoplasia ductal "in situ"+ neoplasia ductal invasora, n = 09. Entre as variáveis anatomopatológicas, o grupo C prevaleceu com 30 casos (50%). O grau nuclear (GN-II) predominou com 45 casos (75%). Em relação as variáveis biológicas o receptor de estrógeno negativo predominou com 41 casos (68,3%), seguido pelo receptor de progesterona negativo com 40 casos (66,7%), podemos dizer que... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The objective of this paper was to study the immunohistochemical efects of Paget's disease, a rare and special carcinoma of the breast, by correlating anatomopathological (histological and nuclear grade) and biological (estrogen and progesterone hormonal receptors, c-erbB-2 protein and p53 protein) factors. Between January 1980 and December 1998, 6303 cases of breast cancer were treated at the Brazilian Institute of Cancer Control; 98 of these were diagnosed with Paget's carcinoma, an incidence of 1.55%. We retrospectively studied 60 of these cases; 38 were excluded due to lack of available sample material. Patient age varied between 26 and 84 years (mean 55.4), clinical and therapeutic information were obtained from patient's medical records considering age at time of diagnosis, tumor size when palpable, clinical stage, and type of surgery performed. Samples of breast tissue were retrieved the Anatomical Pathology Department, I.B.C.C. / MATTOSINHO. After histological review, by two different pathologists, they were classified into four groups: Group A- Paget's disease (pure form) n = 09 Group B- Paget's disease + "in situ" duct neoplasia n = 12 Group C- Paget's disease, invasive duct neoplasia n = 30 Group D- Paget's disease + "in situ" duct neoplasia + invasive duct neoplasia n = 09.Invasive duct neoplasia was the most prevalent anatomopathological variable (Group C, n = 30, 50%). Nuclear grade (GNII) was found in 45 cases (75%). In relation to the biological variables, the negative estrogen receptor was predominant with 41 cases (68.3%), followed by the negative progesterone receptor with 40 cases (66.7%); this correlation had good concordance by the Kappa test. The c-erbB-2 protein was positive in 53 cases (88.3%) and p53 was negative in 47 cases (78.3%). From these results, we concluded that there was no statistical... (Complete abstract click electronic address below)
Doutor
Danz, Peter. "Der moralische Status von Tieren der philosophische Umgang mit widersprüchlichen Intuitionen". Halle/Saale Hallescher Verl, 2006. http://www.hallescher-verlag.de/pages/40_2.html.
Pełny tekst źródłaЧерепанова, Ю. Ю., i М. С. Широкопетлєва. "Деякі аспекти автоматизованого тестування знань мови SQL". Thesis, Warszawa:«Diamond trading tour», 2018. http://xn--e1aajfpcds8ay4h.com.ua/pages/view/1186.
Pełny tekst źródłaPrice, Allison. "Playing the Ideal: Parenthood and Presentation of Idealized Femininity in youth on "Toddlers & Tiaras"". University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1367924148.
Pełny tekst źródłaBastard, Irène. "De proches en pages, de pages en proches : Exploration et réception des informations en ligne". Thesis, Paris, ENST, 2015. http://www.theses.fr/2015ENST0064/document.
Pełny tekst źródłaWhy do people post news on Facebook? What does a post mean compared to other forms ofexpression? And how does this activity contribute to media appropriation? This research focuses on sharing news, meaning an online interaction which uses information. This activity seems to be the social solution to supporting a person's online exploration. “Who shares what with whom?” is the question asked in this research through multiple approaches, both qualitative and quantitative. The first part is an exploration of online artefacts, counts of what media was shared online, and a few interviews. These diverse points of view show that sharing news enhances public expression of information, but only for some users. Sharing news is a limited part of online media consumption and online interaction. The second part of the research looks in detail at teenagers’ practices on Facebook. For young people on Facebook, all expression has to be social and online artefacts are a way to tell somebody one's position on an issue or on a relationship. News may be there to open interactions. The last part of the research deals with a large dataset of individual Facebook data, available thanks to Algopol Application. Analysis of the diversity of publications shows that the news people share online takes into account their offline media preferences and social activities. Sharing news is an online way of expression based on informations’ reception
Bastard, Irène. "De proches en pages, de pages en proches : Exploration et réception des informations en ligne". Electronic Thesis or Diss., Paris, ENST, 2015. http://www.theses.fr/2015ENST0064.
Pełny tekst źródłaWhy do people post news on Facebook? What does a post mean compared to other forms ofexpression? And how does this activity contribute to media appropriation? This research focuses on sharing news, meaning an online interaction which uses information. This activity seems to be the social solution to supporting a person's online exploration. “Who shares what with whom?” is the question asked in this research through multiple approaches, both qualitative and quantitative. The first part is an exploration of online artefacts, counts of what media was shared online, and a few interviews. These diverse points of view show that sharing news enhances public expression of information, but only for some users. Sharing news is a limited part of online media consumption and online interaction. The second part of the research looks in detail at teenagers’ practices on Facebook. For young people on Facebook, all expression has to be social and online artefacts are a way to tell somebody one's position on an issue or on a relationship. News may be there to open interactions. The last part of the research deals with a large dataset of individual Facebook data, available thanks to Algopol Application. Analysis of the diversity of publications shows that the news people share online takes into account their offline media preferences and social activities. Sharing news is an online way of expression based on informations’ reception
Torrens, Arnal Míriam. "Pagesos del Post-Socialisme. Un Estudi de Comunitat a Transilvània". Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/129105.
Pełny tekst źródłaThe collapse of European socialism was the start for a broad range of economic, political, social and ideological changes. These changes led to a series of debates about the models that should guide the process. The restitution of private properties was one of the key issues for the new post-socialist governments, and necessary condition of political and social progress in the framework of a market economy. But two decades later, the economic situation of the countries of Eastern and Central Europe compels us to inquiry on the shortcomings of the neoliberal agenda. In the last decade, Anthropology has developed a critical view of the post-socialist promises based on ethnographical experiences and on the theoretical criticism of neoliberal approaches. Private property rights were wanted by both, liberals (or neoliberals) and peasants, but they pursued different and in most cases incompatible goals. What it happened during the transition was against the expectations previously generated: the devolution of lands to their former owners was accompanied by a 'return' to a subsistence and demonetarized economy and to the reestablishment of rather old customary institutions. This process has taken place in a new macro-political, economic and demographic context, defined by mass emigration, inflation, the consequences of the so-called green revolution, and the agricultural globalization. The aim of the thesis is to contribute to the understanding of the complex situation of therural areas in post-socialist Europe through a case study of a Transylvanian peasant community. On the one hand, the economic peasant culture was seen as an obstacle for the socialist state as far as it wanted to control the agrarian production for feeding the industrial growth. On the other hand, the peasant economy did not fit with the neoliberal schemes, which have been dominant in the post-socialist period. These schemes expect that the market alienation of land, combined with the legal security of ownership, would give to the farmer the incentives he needs in order to innovate, and to increase productivity (Hann, 2003:7). Following the ethnographic account, this thesis poses that the economic efficiency and the legal rules of property must be confronted to the socio-cultural local context. In our case, the local context means a peasant community defined by moral values, customary law, and customary forms of production and property handling. The economic activity in the community is constantly defined by the overlapping of two spheres of social exchange: kinship and neighborhood. In addition, the local culture needs to be contextualized in the current globalized agricultural system of production and trade. The thesis focuses on the ideological, economic, social and moral conflicts, in order to understand the tensions provoked for the economic and political projects imposed first by socialism and afterwards by liberalism.The reliability of the ethnographic account should provide us with a fine-tuned interpretation of the present situation. This can help us to avoid the oversimplifications of both orthodox Marxism and orthodox neoliberalism perspectives.
Daroszewska, A. "Role of osteoprotegerin and p62 in Paget's disease of bone". Thesis, University of Aberdeen, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590957.
Pełny tekst źródłaNicholas, Richard Martin. "A laboratory and clinical study of Paget's disease of bone". Thesis, Queen's University Belfast, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317547.
Pełny tekst źródłaBean, Kent Richard. "Policing the Borders of Identity at The Mormon Miracle Pageant". Bowling Green State University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1124572144.
Pełny tekst źródłaBowers, Ebony. "Social Stereotyping and Self-Esteem of Miss America Pageant Contestants". ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2791.
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