Rozprawy doktorskie: „Oxygen consumption”

1

Li, Jia. "Oxygen consumption and oxygen delivery in children after cardiopulmonary bypass surgery". Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406548.

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2

Low, Clarke Alan. "Transient oxygen consumption rate measurements with the BDT̳M̳ oxygen biosensor system". Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45922.

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Thesis (S. M.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2008.
In title on title page, double-underscored "TM" appears as superscript .
Includes bibliographical references (p. 109-111).
Oxygen consumption rate (OCR) is a reliable indicator of tissue health. Recently, the OCR of isolated human islets has been shown to predict transplant outcome in diabetic mice. The Oxygen Biosensor System (OBS) is a high-throughput, convenient assay that indirectly measures oxygen consumption by measuring oxygen partial pressure, pO2, adjacent to tissue loaded into the OBS multiwell plate. Solving the general species transport equations for a steady-state solution has not accurately converted pO₂ measurements to OCR. Furthermore, the time to reach steady-state is prohibitively long (at least 5 hr). Transient OBS experiments have been conducted and the rate of p02 change has been shown to correlate with the amount of viable tissue, however, no direct relation with OCR has been established. The overall objective of this thesis was to accurately measure OCR using transient OBS measurements. I fabricated flat OBS plates to simplify the geometry for theoretical models, but theoretical simulations did not match well with experimental data. Furthermore, fabricated flat OBS plates did not behave experimentally as would be expected from I-D, slab geometry. Simplified theoretical models were developed to qualitatively understand the effects of silicone rubber thickness, medium volume, and OCR density on the transient behavior of the OBS. It was shown that medium volume and OCR density should be increased as much as well-volume and tissue constraints allow. Commercial OBS plates were used for subsequent experiments, so it was unable to actively control silicone rubber thickness. Transient OBS measurements with both INS-1 cells and islets were correlated with stirred chamber OCR measurements conducted in parallel. The two measurements were linearly related and a calibration curve was developed so that OBS transient measurements could be converted to OCR. The relationship between the two measurements were similar enough for both cells and islets that the calibration curve seems to be independent of tissue geometry.
(cont.) Increased variability of islet tissue caused greater uncertainty about the islet prediction curve. This variability was compared with stirred chamber islet variability and islet sampling is hypothesized to be the underlying cause of high measurement variability with islets.
by Clarke Alan Low.
S.M.

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3

Casanova, Francesco. "maximal oxygen consumption in systemic lupus erythematosus". Thesis, Bangor University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531058.

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4

Sell, D. "Oxygen consumption and water balance in insects". Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354956.

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5

Asano, Shinichi. "Excess postexercise oxygen consumption and interval training". Huntington, WV : [Marshall University Libraries], 2005. http://www.marshall.edu/etd/descript.asp?ref=521.

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6

Hay, Peter Dominic. "Oxygen transfer and consumption within bioartificial liver devices". Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366749.

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7

Shepherd, Brent A. "Predicting Maximal Oxygen Consumption (VO2max) Levels in Adolescents". BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/2997.

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Maximal oxygen consumption (VO2max) is considered by many to be the best overall measure of an individual's cardiovascular health. Collecting the measurement, however, requires subjecting an individual to prolonged periods of intense exercise until their maximal level, the point at which their body uses no additional oxygen from the air despite increased exercise intensity, is reached. Collecting VO2max data also requires expensive equipment and great subject discomfort to get accurate results. Because of this inherent difficulty, it is often avoided despite its usefulness. In this research, we propose a set of Bayesian hierarchical models to predict VO2max levels in adolescents, ages 12 through 17, using less extreme measurements. Two models are developed separately, one that uses submaximal exercise data and one that uses physical fitness questionnaire data. The best submaximal model was found to include age, gender, BMI, heart rate, rate of perceived exertion, treadmill miles per hour, and an interaction between age and heart rate. The second model, designed for those with physical limitations, uses age, gender, BMI, and two separate questionnaire results measuring physical activity levels and functional ability levels, as well as an interaction between the physical activity level score and gender. Both models use separate model variances for males and females.

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8

Hoge, Richard D. "Magnetic resonance imaging of cerebral oxygen consumption and perfusion". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0024/NQ50186.pdf.

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9

Morrison, Paul. "Skate blade hollow and oxygen consumption during forward skating". Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19759.

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The purpose of this study was to investigate the effect of skate blade hollow on oxygen consumption during forward skating on a treadmill. Varsity level female hockey players ( n = 10, age = 21.7 yr) performed skating tests at three blade hollows (0.25 in, 0.50 in, and 0.75 in). The subjects skated for four minutes at three submaximal velocities (12, 14, and 16 km/h), separated by five minutes of passive recovery. In addition, a VO^max test was performed on the day that the subjects skated at the 0.50 in hollow. The VOimax test commenced at 14 km/h and increased by 1 km/h each minute until volitional exhaustion was achieved. Four variables were measured for each skating bout, volume of gas expired (VE), volume of oxygen consumed (VO2), heart rate (HR) and rating of perceived exertion (RPE). No significant differences (pO.05) were found in any of the four test variables (VE, VO2, HR, RPE) across the three skate hollows. These results show that when skating on a treadmill at submaximal velocities, skate blade hollow has no significant effect on VE, VO2, HR or RPE.

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10

Hoge, Richard D. "Magnetic resonance imaging of cerebral oxygen consumption and perfusion". Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35896.

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This dissertation describes both methodological developments in quantitative functional magnetic resonance imaging (fMRI) of cerebral oxygen consumption, and the results of experiments using these techniques to elucidate the mechanisms linking focal changes in blood flow and oxygen metabolism. Technical contributions presented include a novel MRI pulse sequence for simultaneously monitoring cerebral blood flow and tissue oxygenation with high signal-to-noise ratio, as well as an experiment automation system permitting complex multiparametric studies to be carried out efficiently in large numbers of subjects. These tools enabled us to make a number of significant neurophysiological discoveries with important implications for the design and interpretation of fMRI experiments. In particular, relative changes in cerebral perfusion and oxygen consumption were found to be coupled in a consistent linear ratio of approximately 2:1, respectively, in human visual cortex. A quantitative model predicting that oxygenation-sensitive MRI signals must be extremely sensitive to departures from this coupling ratio was also introduced, revealing that combined perfusion/oxygenation measurement during graded activation is a powerful tool for studying regulatory relationships between these parameters. Predictions based on this model were in excellent agreement with experimental results, supporting model-derived estimates of oxygen consumption and suggesting that the ∼2:1 coupling discovered in visual cortex is likely to apply in most cortical systems. Finally, important non-linear characteristics of fMRI signal dynamics in human visual cortex were revealed, challenging current models of fMRI transient response.

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11

White, E. "Respiration chamber-free measurement of oxygen consumption in sheep". Thesis, University of Reading, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372674.

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12

Cox, Christina Lyn. "Effect of Nitric Oxide on Oxygen Consumption of Skeletal Muscle". VCU Scholars Compass, 2006. http://hdl.handle.net/10156/1703.

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13

Clevinger, Curtis. "Nitrifiers and their contribution to oxygen consumption in Lake Erie". Thesis, Kent State University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3617735.

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Nitrification is a prokaryote-mediated oxygen consumptive process of the oxidation of ammonia to nitrite/nitrate that traditionally has been only viewed as a nutrient transformation process. Renewed concern about hypoxia in the shallow hypolimnion of the Central Basin of Lake Erie provides impetus for examining whether nitrification has a significant impact on oxygen dynamics. To evaluate the contribution of nitrification to oxygen demand, water column and sediment samples were collected during the summers of 2008-2010 in Lake Erie and the oxygen consumption due to nitrification and the abundance and distribution of potential bacterial (AOB) and archaeal (AOA) that oxidize ammonia to nitrite was characterized in water column and sediment samples by qPCR of a portion of the ammonia monooxygenase (amoA) gene. Environmental variables and nitrification rates were examined for correlations to understand factors that may control nitrification rates and/or the distribution of nitrifiers. The nitrification rate in the epilimnion and hypolimnion was 3.1 ± 3.2 micromole N/L/day and 3.7 ± 2.9 (mean ± 1 SD) micromole oxygen/L/day respectively. Nitrification accounted for 28.2 ± 23.1% of the total oxygen consumption in the epilimnion and 32.6 ± 22.2% in the hypolimnion. Oxygen consumption by nitrification in sediment slurries and intact sediment cores was 7.1 ± 5.8 micromole oxygen/gram/day and 682 ± 61.1 micromole oxygen/square m/day respectively. Nitrification accounted for 27.0 ± 19.2% of the total oxygen consumption in sediment slurries and 30.4 ± 10.7% in intact sediment cores. AOA and AOB were present in all samples, with a distribution that was variable over time and space. Highlighting the potential importance of archaeal nitrifiers, the AOA/AOB ratio in the epilimnion, hypolimnion, and sediments was 1.02, 1.08, and 5.25. The nitrification rate or nitrifier numbers did not strongly correlate with environmental factors such as oxygen, nitrate or ammonium. In the water column, respiration and the percentage of oxygen used due to nitrification were negatively correlated. While nitrification is unlikely to be the dominant oxygen consumptive process, the rates observed in Lake Erie were sufficient to theoretically deplete a large portion of the hypolimnetic oxygen pool during the stratified period.

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14

Jucht, Kathy Rae. "The influence of age on excess post-exercise oxygen consumption". Virtual Press, 1990. http://liblink.bsu.edu/uhtbin/catkey/722441.

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Oxygen consumption remains elevated above resting values for a variable period of time after exercise. Exercise intensity and duration, food intake, laboratory conditions, metabolic measurements, gender and age are all major factors affecting the duration and magnitude of excess post-exercise oxygen consumption (EPOC). In the present study, the influence of age on EPOC was studied in men of various fitness levels. Various metabolic measurements were collected for three distinct age groups, 18-25, 35-45, and 55-67 at rest and during exercise at 60% of maximal oxygen consumption until 200 ± 10 kilocalories were expended. Immediately after the exercise bout, subjects walked on the treadmill for one minute and then were seated until oxygen consumption returned to within .01 liters of the recorded resting values.Percent body fat, V02 max and exercise V02 were significantly different between age groups. The duration (23-25 minutes) and magnitude (7-11 kilocalories) of EPOC did not differ significantly between groups. However, heart rate and minute ventilation were significantly elevated above resting measurements when V02 reached resting values. In conclusion, the physiological differences associated with the aging process were not found to significantly affect the duration and magnitude of EPOC.
School of Physical Education

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15

Clevinger, Curtis C. "Nitrifiers and their contribution to oxygen consumption in Lake Erie". Kent State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=kent1385130018.

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16

Smith, Adam J. "Resting oxygen consumption rates in divers using diver propulsion devices". [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002686.

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17

Olsson, Kevin, i Valeriy Ivinskiy. "Predicting runners’ oxygen consumption on flat terrain using accelerometer data". Thesis, KTH, Matematisk statistik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-252749.

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This project aimed to use accelerometer data and KPIs to predict the oxygen consumption of runners’ during exercises on flat terrain. Based on many studies researching the relationship between oxygen consumption and running economy and a small set of data, a model was constructed which had a prediction accuracy of 81.1% on one individual. Problems encountered during the research include issues with comparing data from different systems, model nonlinearity and data noise. These problems were solved using transformation of data in the R software, model re-specification and identifying outlying observations that could be viewed as noise. The results from this project should be seen as a proof of concept for further studies, showing that it is possible to predict oxygen consumption using a set of accelerometer data and KPIs. With a larger sample set this model can be validated and furthermore implemented in Racefox’s current service as a calibration method of individual results and an early warning system to avoid running economy deficiency.
Detta projekts målsättning var att använda accelerometerdata och KPI-värden för att prediktera syrekonsumtion för löpare på plan mark. Baserat på ett urval av studier om korrelationen mellan syrekonsumtion och löpekonomi samt en liten mängd data så konstruerades en modell med en förklaringsgrad på 81.1% på en individ. Svårigheter under arbetet inkluderar datajämförelser, icke-linjäriteter och databrus. Detta hanterades genom datatransformationer i mjukvaran R, modell-modifikationer och identifikation av avvikande data som kunde klassificeras som brus. Resultaten kan ses som en förstudie som indikerar att det är möjligt att prediktera syrekonsumtion genom accelerometerdata och KPI-värden. En fortsatt större studie med fler individer och mätningar som underlag kan validera denna slutsats samt då implementeras i Racefoxs nuvarande tjänst som en kalibreringsmetod för individuella resultat och som ett varningssystem för att undvika försämrad löpekonomi.

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18

Smith, Nigel Anthony. "Oxygen consumption and muscle activation patterns during constant load exercise". Thesis, Queensland University of Technology, 2000. https://eprints.qut.edu.au/36769/1/36769_Digitised%20Thesis.pdf.

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The collective purpose of these two studies was to determine a link between the V02 slow component and the muscle activation patterns that occur during cycling. Six, male subjects performed an incremental cycle ergometer exercise test to determine asub-TvENT (i.e. 80% of TvENT) and supra-TvENT (TvENT + 0.75*(V02 max - TvENT) work load. These two constant work loads were subsequently performed on either three or four occasions for 8 mins each, with V02 captured on a breath-by-breath basis for every test, and EMO of eight major leg muscles collected on one occasion. EMG was collected for the first 10 s of every 30 s period, except for the very first 10 s period. The V02 data was interpolated, time aligned, averaged and smoothed for both intensities. Three models were then fitted to the V02 data to determine the kinetics responses. One of these models was mono-exponential, while the other two were biexponential. A second time delay parameter was the only difference between the two bi-exponential models. An F-test was used to determine significance between the biexponential models using the residual sum of squares term for each model. EMO was integrated to obtain one value for each 10 s period, per muscle. The EMG data was analysed by a two-way repeated measures ANOV A. A correlation was also used to determine significance between V02 and IEMG. The V02 data during the sub-TvENT intensity was best described by a mono-exponential response. In contrast, during supra-TvENT exercise the two bi-exponential models best described the V02 data. The resultant F-test revealed no significant difference between the two models and therefore demonstrated that the slow component was not delayed relative to the onset of the primary component. Furthermore, only two parameters were deemed to be significantly different based upon the two models. This is in contrast to other findings. The EMG data, for most muscles, appeared to follow the same pattern as V02 during both intensities of exercise. On most occasions, the correlation coefficient demonstrated significance. Although some muscles demonstrated the same relative increase in IEMO based upon increases in intensity and duration, it cannot be assumed that these muscles increase their contribution to V02 in a similar fashion. Larger muscles with a higher percentage of type II muscle fibres would have a larger increase in V02 over the same increase in intensity.

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19

Martin, David E. "The effect of heat stress on excess post exercise oxygen consumption". Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/834623.

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While a great deal of research has been directed towards the phenomena of excess post exercise oxygen consumption (EPOC), the effect of thermal stress on EPOC is not well defined. To assess the effect of heat stress on EPOC, seven healthy, active subjects (4 female, 3 male; 23.9 ± 2.0 years of age) performed 4 trials: one control (quiet rest) and one exercise (45 minutes of cycling at 65% VO2max workload) trial in moderate (23° C, 50% humidity) and hot (35° C, 50% humidity) environments. Oxygen consumption (V02), heart rate (HR) and rectal temperature (RT) were assessed pre, during and post control or exercise. Subjects were monitored until post exercise VO2 had returned to within ±2% of baseline. EPOC was determined by subtracting baseline VO2 from total V02 during the post exercise period. During the first 15 minutes (acute) post exercise, a significant EPOC (p = 0.0019) was seen in both exercise conditions over both control conditions. During the slow phase (> 15 minutes post exercise to baseline), there was no significant difference between the hot control (HC), moderate exercise (ME), or hot exercise (HE) EPOC. Total time post exercise until baseline was achieved was 35, 44, and 51 minutes for HC, ME, and HE respectively. HR was significantly elevated in both exercise conditions. During the acute post exercise period, HR in HE was elevated above MC, ME and HC (p < 0.05). RT was elevated in both exercise conditions during and post exercise. The present data indicate that heat stress does not have a significant effect on the magnitude or duration of EPOC.
School of Physical Education

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20

Guevara-Lequay, L. V. "The stability and oxygen consumption of retinol at low water activity". Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356425.

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21

Ashmore, Tom. "Dietary nitrate and the integrated control of oxygen delivery and consumption". Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648672.

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22

Gibson, Adrienne Rae. "Pharmacological ascorbate enhances oxygen consumption and epigenetic reprogramming in pancreatic cancer". Thesis, University of Iowa, 2018. https://ir.uiowa.edu/etd/6424.

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Pharmacological ascorbate treatment (P-AscH-, high-dose, intravenous vitamin C) results in a short-term increased flux of H2O2 that is preferentially cytotoxic to cancer cells vs. normal cells. We hypothesized that there may be a sustained effect (> 24 h) of P-AscH- that may contribute to cytotoxicity. P-AscH- significantly increased sustained oxygen consumption (OCR), DCFH-DA oxidation, and extracellular acidification (ECAR) in tumor lines with no change in non-tumorigenic cells. One possible source of this sustained ROS and OCR, the NADPH oxidase family of enzymes Dual Oxidase 1 and 2 (DUOX), which are epigenetically silenced by methylation in vitro and in vivo in PDAC, are up-regulated with P-AscH- treatment. Catalase pretreatment reversed the P-AscH--induced increases in DUOX, while DUOX inhibition partially rescues P-AscH- toxicity. Additionally, nutritional ascorbate is unable to mediate the increase in DUOX expression. Together these results suggest that P-AscH--induced toxicity may be enhanced by late metabolic and epigenetic shifts in tumor cells resulting in a feed-forward mechanism of H2O2 generation and induction of metabolic stress via enhanced DUOX expression and OCR. These data highlight a novel epigenetic mechanism of action for P-AscH-.

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23

Dacey, Jacqueline Marie. "The variability of heart rate response to a submaximal bicycle test given on three consecutive days /". View online, 1987. http://repository.eiu.edu/theses/docs/32211998880451.pdf.

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24

Neely, Aaron Mackallan. "Hypoxia and the Development of Endothermic Capacity in Chickens (Gallus Gallus)". Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc149643/.

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Adult chickens employ endothermy – internal generation of heat that maintains a constant body temperature (Tb). Prior to hatching, chicken embryos are ectothermic - controlling Tb by external heat sources. Upon hatching, the hatchling transitions from an ectotherm to an endotherm that has been shown to be delayed by hypoxia. In this study, whole animal oxygen consumption () and liver, heart, and skeletal muscle citrate synthase activity (CSA) and were measured during this transition to endothermy in chickens incubated in normoxia and hypoxia (15% O2). The only significant differences in occurred in 48 hour old hatchlings where was lower in normoxic hatchlings. There were no differences in CS activity between age and incubation oxygen levels. Additionally, preliminary 2-D protein gels of embryo and hatchling liver show changes in the proteome upon hatching. Results suggest that hypoxia had no significant effect on CSA and a minimal effect on .

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25

Liles, Alexander C. "PO2 DEPENDENCE OF OXYGEN CONSUMPTION IN SKELETAL MUSCLE OF DIABETIC AND NON-DIABETIC RATS". VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4865.

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Abstract PO2 DEPENDENCE OF OXYGEN CONSUMPTION IN SKELETAL MUSCLE OF DIABETIC AND NON-DIABETIC RATS By: Alexander C. Liles A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at the Medical College of Virginia Campus, Virginia Commonwealth University Virginia Commonwealth University, 2017 Advisor: Roland N. Pittman, Ph.D. Department of Physiology and Biophysics Type 2 diabetes mellitus (T2DM) is a major medical problem around the world, affecting nearly 6% of the world’s population. This study was an attempt to better understand physiological changes the disease may cause to the microcirculation and more specifically, to assess the dependence of oxygen consumption in skeletal muscle of a diabetic animal model. The spinotrapezius muscles of Goto-Kakizaki (G-K) and Wistar control rats were used to measure interstitial using phosphorescence quenching microscopy. The G-K rats spontaneously develop T2DM and serve as an appropriate model for the disease in humans. By rapidly arresting blood flow in the tissue and observing the resulting changes, an oxygen disappearance curve (ODC) was created. The ODC was used to calculate oxygen consumption rate (VO2) over the physiological range of PO2 values. The resulting VO2 vs PO2 curves were analyzed using Hill’s equation to fit the data and obtain values of several key parameters to quantitatively describe the PO2 dependence of oxygen consumption. When compared to healthy control rats, the G-K rats exhibited a significantly higher Vmax, or maximum rate of oxygen consumption, compared to the Wistar rats. The two rat sub-strains had similar values for P50, which indicates the PO2 at half maximal consumption. The overall higher maximal rate of consumption by the diseased animals could be explained by some disconnect in the consumption of oxygen by the mitochondria and the normal corresponding production of ATP. In conclusion, it was demonstrated that in situ muscle tissue from both diabetic and non-diabetic rats had a PO2 dependence of oxygen consumption over a wide range of PO2 values and the muscles of diabetic animals consumed oxygen at a higher maximal rate.

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Stagner, Lindsay Gavin Timothy P. "Gender differences in aerobic and work capacity during plantar flexion exercise". [Greenville, N.C.] : East Carolina University, 2009. http://hdl.handle.net/10342/1894.

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Thesis (M.S.)--East Carolina University, 2009.
Presented to the faculty of the Department of Exercise and Sport Science. Advisor: Timothy P. Gavin. Title from PDF t.p. (viewed June 4, 2010). Includes bibliographical references.

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27

Song, Bjorn Kyungsuck. "Effects of Isovolemic Hemodilution on Tissue Oxygen Consumption Using a Hemoglobin-Based Oxygen Carrier and Human Serum Albumin". VCU Scholars Compass, 2007. http://scholarscompass.vcu.edu/etd_retro/33.

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This microcirculatory study compared the effects on oxygen transport of two hemodilution fluids: HBOC-201 (Biopure Corp., Cambridge, MA) a Hemoglobin-Based Oxygen Carrier (HBOC), and 5.9% Human Serum Albumin (HSA) an iso-oncotic non-oxygen carrying colloid solution. Measurements using intravital microscopy were made on the spinotrapezius muscle of male, Sprague-Dawley rats. Interstitial PO2 was measured using phosphorescence quenching microscopy, and recorded before and after isovolemic hemodilutions (HD) at hematocrits of 40% (baseline), 30% (moderate HD) and 15% (severe HD). Oxygen consumption (VO2) of the spinotrapezius muscle was derived from PO2 recordings following the rapid inflation of a plastic bag placed around the objective. When the bag was inflated, blood flow in the muscle was arrested and PO2 rapidly fell over several seconds; the rate of decline of PO2 was proportional to VO2. For moderate HD (Hct ~ 30%) with HBOC-201, interstitial PO2 did not change from baseline conditions (Hct ~ 40%), while HD with HSA showed a decrease. For severe HD (Hct ~ 15%) both PO2 and VO2 were significantly lower for the HSA group than for the HBOC-201 group. These findings indicate that HBOC-201 maintains both a higher PO2 and VO2 during hemodiluted states compared with a non-oxygen carrying colloid solution (HSA). Furthermore, 5.9% HSA does not affect the mean arterial pressure (MAP) and vessel diameters, whereas HBOC-201 causes vasoconstriction, and consequently an increase in MAP. However, the vasoconstriction is not uniform among different branches of the arteriolar network, and most of the changes occur in the larger vessels, i.e., feed and arcade arterioles, while minimal in smaller vessels, i.e., transverse arterioles. In addition, findings show that MAP and vessel diameters return to baseline within 1-3 hours, implying that vasoconstriction and hypertension caused by HBOC-201 are acute responses.

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28

Merola, Alberto. "Development of MRI methods to map cerebral metabolic oxygen consumption in humans". Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/91542/.

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The quantification of brain activity has been one of the main goals of neuroimaging since the earliest applications. In functional magnetic resonance imaging (fMRI) such an aim has been pursued indirectly by studying changes of the blood oxygenation dependent signal triggered by alterations in blood flow following changes in energy metabolism. Such approach is limited because of the complex relationship between the vascular and neural systems in brain tissue. Therefore methods have been proposed to assess oxygen metabolism, which directly underlies energy supply to brain tissue and therefore brain activity. Investigating existing and novel MRI methods, the thesis aims to improve the assessment of oxygen metabolism for a fully quantitative measurement of this biomarker. A simulation study has been carried out to optimise one of the mathematical (fMRI calibration) models used to relate the measured signal to the underlying physiology. As a result we are able to define a new model, less complex and more accurate for estimation of oxygen extraction fraction. Following this, an estimation approach recently developed in our centre is applied to carbon dioxide and oxygen calibrated fMRI data in an experimental setting firstly for a repeatability study and then for a drug study looking at the acute effects of caffeine on brain metabolism and haemodynamics. The precision of the novel approach shows values consistent with previous methods, but with much higher spatial resolution. Exploiting this, acute caffeine effects are characterized with a voxel-wise level of detail, showing results consistent with literature electrophysiological findings. Finally, an innovative method for estimating oxygen extraction fraction, based on velocity spectral imaging and estimation of transverse relaxation time, is introduced and tested at a proof-of-concept level. The performance and limits are examined through simulation and experimentation, suggesting that it might be a viable alternative to the calibration techniques previously introduced.

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29

Grenier, Sylvain. "Internal work measurement and simultaneous oxygen consumption of impaired and normal walking". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0006/MQ36698.pdf.

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30

Knight, Kathleen Elizabeth. "Hindlimb blood flow and oxygen consumption in the late gestation fetal lamb". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0031/NQ38915.pdf.

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31

Gibson, Robert H. "The effect of elevated core temperature upon excess post exercise oxygen consumption". Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/941356.

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A great deal of research has been done to assess the effects of exercise intensity and duration on excess post-exercise oxygen consumption (EPOC). But the effects of an elevated core temperature (Tc) post-exercise have not been directly examined. To assess the effects of an elevated Tc on EPOC, eight healthy, active male subjects (27.5 ± 6.1 years) underwent two 45 minute exercise trials at =70% VO2max in an environmental chamber (36 °C / 10% RH) followed by a 45 minute recovery in either the environmental chamber (42 °C / 10% RH) wearing insulating clothing (HC), or in the ambient conditions of the testing lab (22 °C / 42% RH) without any additional clothing (AM). Oxygen consumption (V02), minute ventilation (VE), heart rate (HR), and rectal temperature (Tc) were recorded pre-, exercise, and post- during both trials. Subjects were monitored postexercise for 45 minutes. EPOC was determined by subtracting pre-trial V02 from the recovery V02 until the difference between the values equaled zero or until 45 minutes had elapsed. Within 25 minutes post-exercise, V02 during the AM recovery had returned to near resting levels (p = 0.146), while V02 during the HC recovery remained significantly elevated for at least 45 minutes (p = 0.027). Given that V02 remained significantly elevated through 45 minutes of recovery, and that all other measured variables (HR, VE, and respiratory exchange ratio) were significantly affected during the HC recovery, it is clear that an elevated Tc has an effect on EPOC.
School of Physical Education

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Schmid, Wolf. "Consumption measurements on SnO 2 sensors in low and normal oxygen concentration". [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11126585.

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Yan, Fu. "Computational modeling of oxygen consumption in the heart based on PET measurements". Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0429103-143658.

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Baba, Reizo, Emiko Mori, Nobuo Tauchi i Masami Nagashima. "Simple exponential regression model to describe the relation between minute ventilation and oxygen uptake during incremental exercise". Nagoya University School of Medicine, 2002. http://hdl.handle.net/2237/5381.

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Miranda, Luis. "Ecological study of oxygen consumption in three species of rattlesnakes, Crotalus Atrox, C. Lepidus, and C. Molossus, (Viperidae) from the northern Chihuahuan Desert". To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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Klippel, Nathan John. "The effects of hip angle manipulation on submaximal oxygen consumption in collegiate cyclists". Thesis, Montana State University, 2004. http://etd.lib.montana.edu/etd/2004/klippel/KlippelN1204.pdf.

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Al-Nsair, Nezam. "A Study in Predicting Oxygen Consumption in Older Women with Diastolic Heart Failure". University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1047065058.

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Lyndon, Alastair Robert. "Protein synthesis in fish in relation to oxygen consumption and free amino acids". Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU546704.

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Protein synthesis was investigated in fish with respect to energetic costs and the effects of feeding. Experiments with cycloheximide were conducted on preparations of isolated, perfused flounder gills. Cycloheximide treatment reduced both oxygen consumption and protein synthesis rates in the gills by 80%. The cost of protein synthesis was calculated to be equivalent to 85 mmol ATP g protein^-1 synthesised. Oxygen consumption and protein synthesis were measured in fasted cod and in animals refed a single meal. In cod fasted for up to 14 days, oxygen consumption and protein synthesis had both fallen to stable values by six days post-feeding. Refeeding after a six day fast caused a rapid increase in both variables, with peak values occurring between 12 and 18 hours after the meal. Maximum oxygen consumption rates were about twice the pre-feeding levels, while protein synthesis increased four-fold. Protein synthesis rates in the liver and stomach responded faster to the meal than the remainder of the body, maximum values occurring at six hours post-feeding. Calculations of the contribution of increased protein synthesis to post-prandial metabolism indicate that it accounts for between 23% and 51% of the increment in oxygen consumption. Changes in the free amino acid pools of tissues and plasma were examined in cod refed a single meal. The only significant changes were in plasma from the heart, with a decrease at six hours post-feeding and an increase at 12 hours. Nevertheless, the mean concentrations of amino acids in the hepatic portal plasma, stomach and white muscle increased at 12 hours or 18 hours post-feeding. This coincided with the timing of maximum whole animal protein synthesis previously observed. It was concluded that protein synthesis is an important contributor to post-prandial metabolism in fish, and that free amino acids might play a role in stimulating protein synthesis after a meal.

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Shah, Habiba. "PO2 dependence of oxygen consumption in skeletal muscle of hypertensive and normotensive rats". VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/5000.

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Human essential hypertension affects over 75 million people in the United States, and can lead to death due to its several serious health complications such as hypertension-related cardiovascular disease. The purpose of this research was to understand how hypertension could cause physiological changes to the microcirculation, specifically the PO2 dependence of oxygen consumption (VO2) in skeletal muscle of normotensive and hypertensive rats. The Spontaneously Hypertensive Rat (SHR) strain was used as the diseased model, and Wistar-Kyoto (WKY) rats were used as controls to conduct this study. The SHR strain develops hypertension between 5-6 weeks after birth with an average systolic blood pressure of 150 mmHg. By arresting blood flow using an objective-mounted inflatable airbag, PO2 measurements were obtained along with an oxygen disappearance curve (ODC), which was used to calculate VO2 over various ranges of physiological PO2 values. PO2 and VO2 curves were analyzed based on Hill’s equation to fit the data and describe the PO2 dependence of VO2. When compared to the healthy Wistar-Kyoto rats, the SHRs exhibited a higher Vmax, or maximum rate of oxygen consumption. The average maximal rate of consumption by the hypertensive animal models could be a consequence of a “mitochondrial uncoupling” or some disconnect in the mitochondrial oxygen consumption and the normal corresponding ATP production. In conclusion, this project demonstrated that in situ muscle tissue from hypertensive and normotensive rats had a PO2 dependence of oxygen consumption over a wide range of physiological PO2 values and the hypertensive rats consumed oxygen at a higher maximal rate.

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Rossiter, Harry Bartlett. "Dynamic inter-relationships between intramuscular high-energy phosphate metabolism and pulmonary oxygen uptake during exercise in humans". Thesis, St George's, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313300.

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McKenna, David Richard. "Biochemical and physical factors affecting color characteristics of selected bovine muscles". Texas A&M University, 2003. http://hdl.handle.net/1969.1/44.

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Nineteen bovine muscles were removed from beef carcasses (n = 9). Muscles were trimmed free of fat, cut into 2.54 cm thick steaks, and were packaged in Styrofoam trays with polyvinylchloride overwrap. Steaks were assigned randomly to a day of retail display (0-, 1-, 2-, 3-, 4-, or 5-d). Steaks were evaluated over the course of retail display for objective measures of discoloration (metmyoglobin, oxymyoglobin, L*-, a*-, and b*-values), reducing ability (metmyoglobin reductase activity, resistance to induced metmyoglobin formation, and nitric oxide metmyoglobin reducing ability), oxygen consumption rate, oxygen penetration depth, myoglobin content, oxidative rancidity, and pH. Muscles were grouped according to objective color measures of discoloration. M. longissimus lumborum, M. longissimus thoracis, M. semitendinosus, and M. tensor fasciae latae were grouped as "high" color stability muscles, M. semimembranosus, M. rectus femoris, and M. vastus lateralis were grouped as "moderate" color stability muscles, M. trapezius, M. gluteus medius, and M. latissimus dorsi were grouped as "intermediate" color stability muscles, M. triceps brachi - long head, M. biceps femoris, M. pectoralis profundus, M. adductor, M. triceps brachi - lateral head, and M. serratus ventralis were grouped as "low" color stability muscles, and M. supraspinatus, M. infraspinatus, and M. psoas major were grouped as "very low" color stability muscles. Generally, muscles of high color stability had high resistance to induced metmyoglobin formation, nitric oxide reducing ability, and oxygen penetration depth and possessed low oxygen consumption rates, myoglobin content, and oxidative rancidity. In contrast, muscles of low color stability had high metmyoglobin reductase activity, oxygen consumption rates, myoglobin content, and oxidative rancidity and low resistance to induced metmyoglobin formation, nitric oxide metmyoglobin reducing ability, and oxygen penetration depth. Data indicate that discoloration differences between muscles are related to the amount of reducing activity relative to the oxygen consumption rate.

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Frifer, Wenasa Salem. "Respiratory Responses in the Freshwater Snail (Pomacea Bridgesii) are Differently Affected by Temperature, Body Mass,and Oxygen Availability". Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc862788/.

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Pomacea bridgesii is a snail species native to tropical and sub-tropical regions, where it usually faces variability in water, temperature and oxygen level. This study of the effect of temperature on mass-specific oxygen consumption (ṀO2) and its relation to body weight shows that the ṀO2 of juvenile snails in normoxia (18-21 kPa) acclimated at temperature of 25°C ranged from 5 to 58 µMol O2/g/h, with a mean of 41.4 ± 18.3 µMol O2/g/h (n=7). Adult snails in normoxia at 25°C show less variation, ranging from 13 to 23 µMol O2/g/h , with a mean of 24.4± 6.1 µMol O2/g/h (n=12). The Q10 value for juvenile snails was higher in the interval 25-30°C (Q 10=5.74) than in the interval 20-25°C (Q10= 0.286). In adult snails, Q10 was higher in the interval 20-25°C (Q10=3.19). ṀO2 of P. bridgesii in relation to body weight showed a negative linear correlation between metabolic rate and body weight with b values between 0.23 and 0.76. Also, both juvenile and adult snails exhibited weak O2 regulation. In general, the different respiratory characteristics between juvenile and adult snails might be related to the differences of individual life history, which caused them to perform differently in face of temperatures change. Additionally, Pomacean snails species originated in tropical habitats where there is a lack of thermal fluctuation. For this reason, Pomacean snails may be less likely to have evolved effective thermal acclimation capabilities.

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Vickery, Rachel. "The effect of breathing pattern retraining on performance in competitive cyclists a thesis submitted to Auckland University of Technology in partial fulfillment of the requirements for the degree of Master of Health Science (MHSc), October 2007 /". Clikc here to access this resource online, 2007. http://aut.researchgateway.ac.nz/handle/10292/83.

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Thesis (MHSc--Health Science) -- AUT University, 2007.
Includes bibliographical references. Also held in print (x, 133 leaves : ill. ; 30 cm.) in North Shore Campus Theses Collection (T 612.22 VIC)

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Zachrich, Timothy P. "Max VO₂ and ventilatory threshold in university level hockey players". Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1210886896.

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Skovereng, Knut. "Oxygen consumption in cycling: The difference between the whole body and the local muscles". Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bevegelsesvitenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-13162.

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Introduction: Oxygen consumption during exercise has been extensively studied with the focus primarily on whole body oxygen consumption (tVO2). The purpose of this thesis was to use Near-infrared spectroscopy (NIRS) to compare tVO2 to oxygen consumption in the local muscles (mVO2) at increasing work rate. Method: 18 male cyclists performed an incremental cycling test until exhaustion. tVO2 was measured through pulmonary gas exchange and mVO2 was measured using NIRS in combination with arterial occlusion (AO). mVO2 was measured in the vastus medialis (VM) and vastus lateralis (VL) muscles. Results: tVO2 showed an linear increase with increasing work rate. However, tVO2 showed an initially faster increase followed by a slower increase with increased work rate when compared to tVO2. No increase in cadence was seen with increasing work rate. Discussion: The main finding was a significant different effect of work rate on mVO2 and tVO2. The steep increase in mVO2 during low intensity exercise found in the present study indicates that the VM and VL muscles are activated at an early stage during increasing intensity. The results from the present study indicate that there are differences between what happens in the local muscle and what is observed when looking at the whole body. The increase in work rate with no observed increase in cadence may indicate increased intramuscular pressure which may occlude blood flow in the muscle and thus be part of the reason for the decrease in mVO2 seen at high intensity. Conclusion: This study shows that care should be taken with results from tVO2 for practical application because the mechanisms at the local level are more complex and deviate substantially from that what you can derive from whole body measurements. Key words: Near-infrared spectroscopy, cycling, local muscle VO2, mVO2, whole body VO2, tVO2, vastus lateralis, vastus medialis.

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Brown, Michael A. "Non-invasive determination of myocardial oxygen consumption with "C-acetate and positron emission tomography /". Title page, contents and abstract only, 1994. http://web4.library.adelaide.edu.au/theses/09MD/09mdb883.pdf.

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Auchterlonie, Neil Alexander. "Oxygen consumption and bioenergetics of the Atlantic halibut (Hippoglossus hippoglossus L.) : implications for culture". Thesis, University of Stirling, 1998. http://hdl.handle.net/1893/1917.

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Aspects of oxygen consumption and bioenergetics of the Atlantic halibut (Hippoglossus hippoglossus L. ) were studied under laboratory conditions. Resting oxygen consumption rate was monitored over 36 hour periods in Atlantic halibut while held individually in open system respirometers. Routine oxygen consumption rate was determined in small populations of tank held Atlantic halibut over 24 hour periods, through modification of tank systems as open system respirometers. Values for resting and routine oxygen consumption in this species were quantified and models Produced enabling the prediction of the energetic cost of homeostasis and spontaneousa ctivity for a range of fish size from 53g to 5861g, at temperatures of 6, 10 and 14°C. These results were ftirther used to form the basis of an energy budget equation for this species. PhotoPeriod influences on the periodicity of respiratory rhythm in both resting and routine oxygen consumption trials were determined through analysis of data recorded throughout the 24 hour daily period. The results indicated a cyclic respiratory rhythm, with peak oxygen consumption often observed nocturnally. The relevance of these results to culture of this organism are discussed. Post-prandial oxygen consumption and ammonia excretion were measured in small populations of tank held Atlantic halibut, these results contributing further information to the partitioning of energy within the metabolic and excretory components of the energy budget equation. Values for resting, routine and postprandial oxygen consumption in the Atlantic halibut were found to be low in comparison to roundfish species, but corresponded closely with literature data produced for other species of temperate marine flatfish. Activity patterns in small populations of Atlantic halibut were monitored over 24 hour periods in a specially constructed film unit. The results of this work showed dualistic patterns of activity over the diurnal cycle. Further elucidation of the energy budget was achieved through the determination of the metabolic costs of activity in the tank environment. Atlantic halibut were observed to remain at rest for periods of between 76% and 94% of any 24 hour period, with the time at rest dependent on fish size and stocking density. One 28 day trial was undertaken in which the components of the energy budget were measured simultaneously, and the balance of the budget investigated. Oxygen consumption, ammonia excretion, growth, feed consumption and faecal production were monitored within a purpose built experimental unit, and these values finther applied to the construction of an energy budget model. Finally, the oxygen consumption data of this study was ftirther applied to produce a model quantifying the water requirements of this species in a single-pass tank system, for the intensive culture of this species in the tank environment. Further development of these figures allowed the quantification of the pumping costs in an Atlantic halibut ongrowing tank system, and these figures were incorporated into a simple economic model. The results present some of the first bioenergetic data produced for this species, and this is an important step towards the development of an Atlantic halibut farming industry.

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Hassan, Ismail Abdel-Aleem. "Measurement of peripheral oxygen consumption in neonates using near infrared spectroscopy : development and evaluation". Thesis, Keele University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368987.

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Gallardo, Celeste. "The Influence of Incubation Conditions on Oxygen Consumption During the Development of Pantherophis guttatus". Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/etd/3929.

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The flexible shell of some oviparous reptiles has led to differences in nutrient mobilization and water relations when compared to their rigid-shelled counterparts. Flexible-shelled eggs gain more water during development, and because of the shell structure, yolk calcium content is higher than that of eggshells. When water availability is altered for reptiles with flexible-shelled eggs, differences in both energy and nutrient utilization are observed. This study was designed to determine the baseline metabolic rate during development for the snake, Pantherophis guttatus under normal conditions, and to observe how changes in eggshell calcium and water availability impact embryonic oxygen consumption. Eggshell calcium was decreased while water uptake was increased by removing the outer calcareous eggshell layer from some eggs. When eggs are left intact, an exponential increase in oxygen consumption is observed, supporting previous studies, while removal of the eggshell produces no effect on metabolism.

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Spieckermann, Mathias Johannes [Verfasser]. "Controls of Oxygen Consumption of Sediments in the Upper Elbe Estuary / Mathias Johannes Spieckermann". Hamburg : Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2021. http://d-nb.info/1239814801/34.

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