Rozprawy doktorskie na temat „Nuclear magnetic resonance”
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Sklar, Howard Fred. "Nuclear magnetic resonance logging". Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/10503.
Pełny tekst źródłaIncludes bibliographical references (leaves 119-121).
by Howard Fred Sklar.
M.S.
Tang, Xiao-wu 1972. "Nuclear magnetic resonance microscopy". Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/9542.
Pełny tekst źródłaIncludes bibliographical references (leaves 96-100).
This thesis describes the design and applications of an improved Nuclear Magnetic Resonance (NMR) microscope, which permits MRI to study small sample sizes ( < 2mm) at high resolution (up to 2[mu]m). The effects of molecular diffusion and local variations in the magnetic susceptibility in NMR microscopy are described, which, along with the intrinsic low sensitivity of NMR, are the fundamental limitations to resolution. Molecular diffusion in the presence of a magnetization grating not only broadens the point spread function but also reduces the signal intensity. The significance of these effects depends strongly on the magnetic field gradient strengths and imaging protocols. A NMR microscope for a standard bore 14.lT magnet was developed, it is equipped with a highly efficient. solenoidal RF coil and three orthogonal gradients with strengths of 1260G / cm for Gz , 760G/cm for Gy , and 410G/cm for Gx at 15A. A modified CTI sequence is presented which incorporates strong pulsed gradients, Ernst angle excitation, CP coherent detection and reduced k-space sampling. It is the optimal pulse sequence for acquiring high-resolution ( < 5[mu]m) NMR images (best signal-to-noise ratio per unit time) when the effect of molecular diffusion is significant. It is demonstrated that this new sequence makes it possible to acquire images with a high resolution of 2[mu]m x 2[mu]m x 8[mu]m within a few hours. A wide variety of images have been acquired using the new microscope, and representative images are presented to demonstrate the potential of NMR microscopy as a new tool in developmental biology research. In particular, used in combination with other biological techniques, NMR microscopy can provide a robust, non-invasive, 3D imaging approach to quantifying changes in structure due for instance to radiative exposure, therapy, and natural growth or genetic modifications.
by Xiao-wu Tang.
Ph.D.
Norwood, Timothy John. "Nuclear magnetic resonance in inhomogeneous magnetic fields". Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24875.
Pełny tekst źródłaScience, Faculty of
Chemistry, Department of
Graduate
Briand, Jacques. "Spatially localized nuclear magnetic resonance". Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/29062.
Pełny tekst źródłaScience, Faculty of
Chemistry, Department of
Graduate
Broadhurst, R. William. "Flash photolysis nuclear magnetic resonance". Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257654.
Pełny tekst źródłaLing, Yibo. "Nuclear magnetic resonance readable sensors". Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57705.
Pełny tekst źródłaPage 104 blank. Cataloged from PDF version of thesis.
Includes bibliographical references.
The monitoring of physiological biomarkers is fundamental to the diagnosis and treatment of disease. We describe here the development of molecular sensors which can be read by magnetic resonance (MR) relaxometry. MR is an advantageous bio-sensor readout because it can be determined from opaque samples and through intervening layers of matter. Wash steps can therefore be avoided in in vitro MR assays and non-invasive interrogation achieved for in vivo MR sensing. Functionalized magnetic nanoparticles originally developed as in vivo contrast agents have recently been adapted for use in magnetic relaxometry assays. The first half of this thesis describes a simple particle functionalization strategy and its application to the detection of myocardial infarction ("heart attack") associated biomarkers. The particles were subcutaneously implanted in the form of small discrete sensors and shown to be efficacious in measuring the physiological release of three protein biomarkers. Alternative contrast mechanisms may also be employed by MR readable sensors. The second half of this thesis introduces the novel use of 'smart' polymers which produce analyte-responsive changes in MR relaxivity. We show that MR responsive calcium-crosslinked and pH-swelling hydrogels can be incorporated within discrete sensors.
by Yibo Ling.
Ph.D.
Meier, Benno. "Nuclear Magnetic Resonance in pulsed high magnetic fields". Doctoral thesis, Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-101205.
Pełny tekst źródłaChen, Cheng. "NUCLEAR QUADRUPLE RESONANCE AND LOW-FIELD NUCLEAR MAGNETIC RESONANCE FOR MATERIALS AUTHENTICATION". Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1567518073598426.
Pełny tekst źródłaMunasinghe, B. D. Jeeva P. "Nuclear magnetic resonance imaging of mice". Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337912.
Pełny tekst źródłaGao, Yuan. "Nuclear magnetic resonance studies of cytochromes". Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292649.
Pełny tekst źródłaHarvey, I. "Nuclear magnetic resonance scanning in schizophrenia". Thesis, University of Edinburgh, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652194.
Pełny tekst źródłaJones, Jonathan A. "Nuclear magnetic resonance data processing methods". Thesis, University of Oxford, 1992. http://ora.ox.ac.uk/objects/uuid:7df97c9a-4e65-4c10-83eb-dfaccfdccefe.
Pełny tekst źródłaPowell, Matthew R. "Nuclear magnetic resonance studies of emulsions". Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243476.
Pełny tekst źródłaHorsfield, Mark Andrew. "Nuclear Magnetic Resonance in petroleum engineering". Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334172.
Pełny tekst źródłaMcIntyre, Lisa. "New techniques in nuclear magnetic resonance". Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387033.
Pełny tekst źródłaHancorn, Simon Douglas John. "Nuclear magnetic resonance in inhomogeneous fields". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389838.
Pełny tekst źródłaWilkins, Christine Linda. "Nuclear magnetic resonance studies on myoglobin". Thesis, University of Leicester, 1992. http://hdl.handle.net/2381/33994.
Pełny tekst źródłaSun, Phillip Zhe 1975. "Nuclear magnetic resonance microscopy and diffusion". Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/29996.
Pełny tekst źródłaIncludes bibliographical references.
The goal of the work described in this thesis is to develop the methodology and instrumentation for studying neuron physiology and activation in vivo at near cellular resolution. Using biocompatible crosslinked Hemoglobin (xHb) as a contrast agent, we demonstrated partial local oxygen pressure (pO₂) monitoring in vivo with a home-built high resolution microscopy imaging probe. It is one of the most stable microimaging system designed and fully equipped for microscopic fMRI study. This work is an advancement of using MRI to study fundamental neuron science and cell signal pathways in vivo. NMR Microscopy of pancreatic islet of NOD-SCID mice in vitro has shown the feasibility of tracking T-lymphocytes infiltration into islets before the onset of any diabetes symptoms using contrast agents CLIO-Tat. Application of this to in vivo study will not only advance our understanding of the progression IDDM but also help monitor the treatment and prognosis of IDDM patients. Throughout the high resolution imaging studies at high field (14.1 T), a new gradient sequence was developed to suppress the distortion due to the internal fields. This sequence can faithfully measure the displacement propagator in q-space imaging, and provide the proper displacement contrast in k-space imaging. The constant time imaging technique has been used to image a phantom model of a vascular system. It is made up of two glass tubes, filled with solutions of D[sub]y - DTPA and C[sub]uSO₄ respectively and the field mapping showed significant internal field introduced by their susceptibility difference. The new sequence may find applications in clinical Diffusion Tensor Imaging (DTI) and Diffusion Weighted Imaging (DWI).
by Philip Zhe Sun.
Ph.D.
Barker, P. B. "New techniques in nuclear magnetic resonance". Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375213.
Pełny tekst źródłaPatel, Sunil U. "Nuclear magnetic resonance spectroscopy and ultrasound". Thesis, Aston University, 1989. http://publications.aston.ac.uk/9708/.
Pełny tekst źródłaNorwood, Timothy John. "Nuclear magnetic resonance in homogeneous and inhomogeneous magnetic fields". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304456.
Pełny tekst źródłaMassin, Charles. "Microfabricated planar coils in nuclear magnetic resonance /". [S.l.] : [s.n.], 2004. http://library.epfl.ch/theses/?nr=2913.
Pełny tekst źródłaPodgorsak, Matthew B. "Fricke radiation dosimetry using nuclear magnetic resonance". Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=59290.
Pełny tekst źródłaXu, Ping. "New methods in nuclear magnetic resonance spectroscopy". Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239177.
Pełny tekst źródłaCavanagh, John. "New techniques in nuclear magnetic resonance spectroscopy". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293707.
Pełny tekst źródłaWu, Xi-Li. "New techniques in nuclear magnetic resonance spectroscopy". Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385872.
Pełny tekst źródłaBadar-Goffer, Ronnitte S. "Nuclear magnetic resonance studies of cerebral metabolism". Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335591.
Pełny tekst źródłaGatehouse, Peter David Richard. "Rapid nuclear magnetic resonance imaging of bloodflow". Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300967.
Pełny tekst źródłaBowdrey, Mark David. "Implementing quantum circuits using nuclear magnetic resonance". Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398155.
Pełny tekst źródłaCummins, Holly Katherine. "Quantum information processing and nuclear magnetic resonance". Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393477.
Pełny tekst źródłaClaridge, Timothy David William. "Protein studies by nuclear magnetic resonance spectroscopy". Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303628.
Pełny tekst źródłaWormald, Philip. "Nuclear magnetic resonance spectroscopy of vinylidenefluoride polymers". Thesis, Durham University, 2005. http://etheses.dur.ac.uk/2615/.
Pełny tekst źródłaRaven, C. I. "Nuclear magnetic resonance studies of surfactant systems". Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235350.
Pełny tekst źródłaJones, David Nigel Mark. "Nuclear magnetic resonance spectroscopy of bacterial polysaccharides". Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316713.
Pełny tekst źródłaZimmerman, Clarissa Lynette. "Low-field classroom nuclear magnetic resonance system". Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/61245.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references (p. 109).
The goal of this research was to develop a Low-field Classroom NMR system that will enable hands-on learning of NMR and MRI concepts in a Biological-Engineering laboratory course. A permanent magnet system, designed using finite-element modeling software, was built to produce a static field of Bo = 0.133 Tesla. A single coil was used for both transmitting the excitation pulses and detecting the NMR signal. The probe circuit is essentially an LC tank with a tunable resonant frequency. An FPGA is used to produce the excitation pulses and process the received NMR signals. This research has led to the ability to observe Nuclear Magnetic Resonance. 'Spin- Lattice' and 'Spin-Spin' relaxation times of glycerin samples can easily be measured. Future work will allow further MRI exploration by incorporating gradient magnetic field coils.
by Clarissa Lynette Zimmerman.
M.Eng.
Damion, Robin A. "Grassmann variables and pseudoclassical Nuclear Magnetic Resonance". Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-214290.
Pełny tekst źródłaBrouwer, William J. "Nuclear magnetic resonance studies of relaxor ferroelectrics". W&M ScholarWorks, 2005. https://scholarworks.wm.edu/etd/1539623478.
Pełny tekst źródłaLuck, Stanley David. "The role of magnetic field gradients in nuclear magnetic resonance". Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/27541.
Pełny tekst źródłaScience, Faculty of
Chemistry, Department of
Graduate
Chen, Yin-Ching Iris. "A magnetic resonance approach to neurodegeneration". Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/44490.
Pełny tekst źródłaSehgal, Akansha. "Methodology for nuclear magnetic resonance and ion cyclotron resonance mass spectrometry". Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066491/document.
Pełny tekst źródłaThis thesis encompasses methodological developments in both nuclear magnetic resonance and Fourier transform ion cyclotron resonance mass spectrometry. The NMR section explores the effects of scalar relaxation on a coupled nucleus to measure fast exchange rates. In order to quantify these rates accurately, a precise knowledge of the chemical shifts of the labile protons and of the scalar couplings is normally required. We applied the method to histidine where no such information was available a priori, neither about the proton chemical shifts nor about the one-bond scalar coupling constants J(1H15N), since the protons were invisible due to fast exchange. We have measured the exchange rates of the protons of the imidazole ring and of amino protons in histidine by indirect detection via 15N. Not only the exchange rate constants, but also the elusive chemical shifts of the protons and the coupling constants could be determined. For the mass spectrometry section, the ion isolation project was initiated to study the effect of phase change of radiofrequency pulses. Excitation of ions in the ICR cell is a linear process, so that the pulse voltage required for ejecting ions must be inversely proportional to the pulse duration. A continuous sweep pulse propels the ion to a higher radius, whereas a phase reversal causes the ion to come to the centre. This represents the principle of ‘notch ejection’, wherein the ion for which the phase is reversed is retained in the ICR cell, while the remaining ions are ejected. The manuscript also contains a theoretical chapter, wherein the ion trajectories are plotted by solving the Lorentzian equation for the three-pulse scheme used for two-dimensional ICR. Through our simulations we mapped the ion trajectories for different pulse durations and for different phase relations
Urban, Jeffry Todd. "Nuclear magnetic resonance studies of quadrupolar nuclei and dipolar field effects". Berkeley, Calif. : Oak Ridge, Tenn. : Lawrence Berkeley National Laboratory ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2004. http://www.osti.gov/servlets/purl/836811-joXo6p/native/.
Pełny tekst źródłaPublished through the Information Bridge: DOE Scientific and Technical Information. "LBNL--56768" Urban, Jeffry Todd. USDOE Director. Office of Science. Office of Basic Energy Sciences (US) 12/21/2004. Report is also available in paper and microfiche from NTIS.
Meng, Jiqun J. "Line scan proton magnetic resonance spectroscopic imaging". Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/36963.
Pełny tekst źródłaGoloshevsky, Artem. "Development of a micro nuclear magnetic resonance system /". For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.
Pełny tekst źródłaCousin, Samuel. "Two-field nuclear magnetic resonance : spectroscopy and relaxation". Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066354/document.
Pełny tekst źródłaWe present the development of multiple-field liquid-state NMR spectroscopy for the determination of the structure and dynamics of small molecules and proteins. Dynamics of proteins side-chains in the pico- to nanosecond range have been studied in the protein ubiquitin, by measuring the relaxation of carbon-13 nuclei in isoleucine-δ1 methyl groups, with site-specific isotope labelling. High-field relaxation rates and longitudinal relaxation rates obtained using high-resolution relaxometry have been analysed using a new version of the program ICARUS, adapted for methyl groups. The relaxation matrix has been calculated with a homemade program called RedKite. Models of spectral density function have been proposed to account for all motions of methyl groups. This unprecedented dataset allows for the description of motions in methyl groups over 3 orders of magnitudes of correlation times. Two-field NMR has been developed in collaboration with Bruker. The two-field NMR spectrometer allows for the control of nuclear spins in two magnetic centres with vastly different magnetic fields, coupled with a sample shuttle. Using zero-quantum coherences, homo and heteronuclear two-field high-resolution spectra have been obtained, where the two dimensions are acquired at very different magnetic fields. Such pulse sequences have been used to reduce the contribution of chemical exchange to transverse relaxation, even when this exchange makes signals invisible at high field. The reduced bandwidth of signals at low field has also been used to perform efficient isotropic mixing in a two-field TOCSY experiment. Correlations have been observed for carbon-13 signals separated by more than 150 ppm
Gjersing, Erica Lee. "Nuclear Magnetic Resonance Microscopy of Staphylococcus epidermidis Biofilms". Thesis, Montana State University, 2004. http://etd.lib.montana.edu/etd/2004/gjersing/GjersingE04.pdf.
Pełny tekst źródłaCorum, Curtis A. "Nuclear Magnetic Resonance with the Distant Dipolar Field". Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1108%5F1%5Fm.pdf&type=application/pdf.
Pełny tekst źródłaMeißner, Thomas. "Exploring Nuclear Magnetic Resonance at the Highest Pressures". Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-115023.
Pełny tekst źródłaDuce, Suzanne Louise. "Nuclear magnetic resonance imaging and spectroscopy of food". Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240194.
Pełny tekst źródłaGates, Andrew R. C. "Blood flow studies using nuclear magnetic resonance imaging". Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260496.
Pełny tekst źródłaHodgkinson, Paul. "Non-linear sampling of nuclear magnetic resonance data". Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294326.
Pełny tekst źródła