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Artykuły w czasopismach na temat "Nanoparticle Surface"

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Semchuk, O. Yu, O. O. Havryliuk i A. A. Biliuk. "Kinetic theory of surface plasmon resonance in metal nanoparticles". Surface 12(27) (30.12.2020): 3–19. http://dx.doi.org/10.15407/surface.2020.12.003.

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In recent years, interest in studying the optical properties of metallic nanostructures has grown. This interest is primarily related to the possibility of practical application of such nanostructures in quantum optical computers, micro- and nanosensors. These applications are based on the fundamental optical effect of surface plasmon excitation. The consequence of this phenomenon is surface plasmon resonance (SPR) - an increase in the cross section of energy absorption by a metal nanoparticle as the frequency of incident light (laser radiation) approaches the SPR frequency of the nanoparticle. Plasmon structures are used to improve the efficiency of thin-film SC. In such structures, metal nanoparticles can primarily act as additional scattering elements for the long-wavelength component of sunlight illuminating SC. As a collective phenomenon, SPR can be described using kinetic approaches, ie using the Boltzmann kinetic equation for the conduction electrons of metal nanoparticles. In this work, the theory of SPR based on the kinetic equation for the conduction electrons of nanoparticles is constructed. to the well-known results derived from the Drude-Sommerfeld theory. Second, the kinetic method makes it possible to study metal nanoparticles with sizes larger or ptical conductivity tensor for spheroidal metal nanoparticles. It is shown that the effect of nanoparticle asymmetry on the ratio of the components of the optical conductivity tensor differs not only smaller than the average electron free path length. The developed theory is used to calculate the oquantitatively but also qualitatively in high-frequency and low-frequency surface scattering. It was found that in metal nanoparticles in a dielectric matrix, under SPR conditions, the full width of the SPR line in a spherical metal nanoparticle depends on both the radius of the particle and the frequency of the electromagnetic (laser) radiation exciting this SPR. It is shown that oscillations of the SPR line width with a change in the dielectric constant of the medium in which they are located can be observed in metal nanoparticles. The magnitude of these oscillations is greater the smaller the size of the nanoparticle and increases significantly with increase. As the radius of the spherical nanoparticle increases, the width of the SPR line decreases significantly and prevails around a certain constant value in media with a higher value of dielectric constant.
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Albarki, Mohammed A., i Maureen D. Donovan. "Uptake of Cationic PAMAM-PLGA Nanoparticles by the Nasal Mucosa". Scientia Pharmaceutica 90, nr 4 (25.11.2022): 72. http://dx.doi.org/10.3390/scipharm90040072.

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Nanoparticles provide promising advantages in advanced delivery systems for enhanced drug delivery and targeting. The use of a biodegradable polymer such as PLGA (poly lactic-co-glycolic acid) promotes improved nanoparticle safety and, to some extent, provides the ability to modify nanoparticle surface properties. This study compared the effect of altering the surface charge on the translocation of PLGA nanoparticles across excised nasal mucosal tissues. Nanoparticles (average diameter of 60–100 nm) loaded with Nile Red (lipophilic fluorescent dye) were fabricated using a nanoprecipitation method. The effects of nanoparticle surface charge were investigated by comparing the transfer of untreated nanoparticles (negatively charged) and positively charged PLGA nanoparticles, which were modified using PAMAM dendrimer (polyamidoamine, 5th generation). All nanoparticles were able to be transferred in measurable quantities into both nasal respiratory and olfactory mucosae within 30 min. The total nanoparticle uptake was less than 5% of the nanoparticle mass exposed to the tissue surface. The cationic nanoparticles showed a significantly lower transfer into the mucosal tissues where the amount of nanoparticles transferred was 1.8–4-fold lower compared to the untreated negatively charged nanoparticles. The modification of the nanoparticle surface charge can alter the nanoparticle interaction with the nasal epithelial surface, which can result in decreasing the nanoparticle transfer into the nasal mucosa.
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Zhang, Fei Hu, Xiao Zong Song, Yong Zhang i Dian Rong Luan. "Polishing of Ultra Smooth Surface with Nanoparticle Colloid Jet". Key Engineering Materials 404 (styczeń 2009): 143–48. http://dx.doi.org/10.4028/www.scientific.net/kem.404.143.

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A nanoparticle colloid jet machining system has been developed for polishing ultra smooth surface of brittle materials. Interaction between nanoparticles and work surface in nanoparticle colloid jet machining has been given, and the theoretical dependence of the material removal rate with various important process parameters of the nanoparticle colloid jet machining have been investigated through material removal experiments. Some material removal results of nanoparticle colloid jet machining show that it is possible to obtain removal rates of one nanometer level per minute for glass surfaces with appropriate machining process parameters. A K9 glass surface was polished for obtaining ultra smooth surface. The surface roughness value of atomic force microscopy (AFM) observations is under 1nm Rms.
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Lee, Hwankyu. "Molecular Modeling of Protein Corona Formation and Its Interactions with Nanoparticles and Cell Membranes for Nanomedicine Applications". Pharmaceutics 13, nr 5 (29.04.2021): 637. http://dx.doi.org/10.3390/pharmaceutics13050637.

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The conformations and surface properties of nanoparticles have been modified to improve the efficiency of drug delivery. However, when nanoparticles flow through the bloodstream, they interact with various plasma proteins, leading to the formation of protein layers on the nanoparticle surface, called protein corona. Experiments have shown that protein corona modulates nanoparticle size, shape, and surface properties and, thus, influence the aggregation of nanoparticles and their interactions with cell membranes, which can increases or decreases the delivery efficiency. To complement these experimental findings and understand atomic-level phenomena that cannot be captured by experiments, molecular dynamics (MD) simulations have been performed for the past decade. Here, we aim to review the critical role of MD simulations to understand (1) the conformation, binding site, and strength of plasma proteins that are adsorbed onto nanoparticle surfaces, (2) the competitive adsorption and desorption of plasma proteins on nanoparticle surfaces, and (3) the interactions between protein-coated nanoparticles and cell membranes. MD simulations have successfully predicted the competitive binding and conformation of protein corona and its effect on the nanoparticle–nanoparticle and nanoparticle–membrane interactions. In particular, simulations have uncovered the mechanism regarding the competitive adsorption and desorption of plasma proteins, which helps to explain the Vroman effect. Overall, these findings indicate that simulations can now provide predications in excellent agreement with experimental observations as well as atomic-scale insights into protein corona formation and interactions.
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Sit, Izaac, Haibin Wu i Vicki H. Grassian. "Environmental Aspects of Oxide Nanoparticles: Probing Oxide Nanoparticle Surface Processes Under Different Environmental Conditions". Annual Review of Analytical Chemistry 14, nr 1 (5.06.2021): 489–514. http://dx.doi.org/10.1146/annurev-anchem-091420-092928.

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Surface chemistry affects the physiochemical properties of nanoparticles in a variety of ways. Therefore, there is great interest in understanding how nanoparticle surfaces evolve under different environmental conditions of pH and temperature. Here, we discuss the use of vibrational spectroscopy as a tool that allows for in situ observations of oxide nanoparticle surfaces and their evolution due to different surface processes. We highlight oxide nanoparticle surface chemistry, either engineered anthropogenic or naturally occurring geochemical nanoparticles, in complex media, with a focus on the impact of ( a) pH on adsorption, intermolecular interactions, and conformational changes; ( b) surface coatings and coadsorbates on protein adsorption kinetics and protein conformation; ( c) surface adsorption on the temperature dependence of protein structure phase changes; and ( d) the use of two-dimensional correlation spectroscopy to analyze spectroscopic results for complex systems. An outlook of the field and remaining challenges is also presented.
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Mukha, Iu P., N. V. Vityuk, A. M. Eremenko i M. A. Skoryk. "Stabilization of metal nanoparticles in highly concentrated colloids". Surface 12(27) (30.12.2020): 337–45. http://dx.doi.org/10.15407/surface.2020.12.337.

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Gold and silver nanoparticles (NPs) have a great potential in nanomedicine. For their use in biological studies there is a need to increase significantly the metal content (active substance) in the dose volume for the injection. Therefore, an urgent task is to find the experimental ways to prevent NPs aggregation in highly concentrated colloidal systems. In this work colloids of Ag NPs, Au NPs and AgAu NPs were prepared in the presence of amino acid as metal ion reducer and particle stabilizer. The polymer pluronic F68 was proposed to increase the stability of NPs and the experimental conditions for the long-term stabilization of colloidal systems with a metal content of 0.4-0.8 mg/ml were developed. It was shown that nanoparticles in all systems maintained nanodimensionality during and after the increasing metal concentration in colloids by 40 times, namely the average size of formed particles was around 10-20 nm. Their optical characteristics remained unchanged, namely, the maxima of the localized surface plasmon resonance band in the absorption spectra had typical position and were placed between 415 and 528 nm depending on molar ratio of metal in nanoparticle.
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Zobel, Mirijam. "Observing structural reorientations at solvent–nanoparticle interfaces by X-ray diffraction – putting water in the spotlight". Acta Crystallographica Section A Foundations and Advances 72, nr 6 (6.10.2016): 621–31. http://dx.doi.org/10.1107/s2053273316013516.

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Nanoparticles are attractive in a wide range of research genres due to their size-dependent properties, which can be in contrast to those of micrometre-sized colloids or bulk materials. This may be attributed, in part, to their large surface-to-volume ratio and quantum confinement effects. There is a growing awareness that stress and strain at the particle surface contribute to their behaviour and this has been included in the structural models of nanoparticles for some time. One significant oversight in this field, however, has been the fact that the particle surface affects its surroundings in an equally important manner. It should be emphasized here that the surface areas involved are huge and, therefore, a significant proportion of solvent molecules are affected. Experimental evidence of this is emerging, where suitable techniques to probe the structural correlations of liquids at nanoparticle surfaces have only recently been developed. The recent validation of solvation shells around nanoparticles has been a significant milestone in advancing this concept. Restructured ordering of solvent molecules at the surfaces of nanoparticles has an influence on the entire panoply of solvent–particle interactions during, for example, particle formation and growth, adhesion forces in industrial filtration, and activities of nanoparticle–enzyme complexes. This article gives an overview of the advances made in solvent–nanoparticle interface research in recent years: from description of the structure of bulk solids and liquidsviamacroscopic planar surfaces, to the detection of nanoscopic restructuring effects. Water–nanoparticle interfaces are given specific attention to illustrate and highlight their similarity to biological systems.
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Kim, Ji-Su, Byung-Kook Kim i Yeong-Cheol Kim. "Effect of Cu Alloying on S Poisoning of Ni Surfaces and Nanoparticle Morphologies Using Ab-Initio Thermodynamics Calculations". Journal of Nanoscience and Nanotechnology 15, nr 10 (1.10.2015): 8205–10. http://dx.doi.org/10.1166/jnn.2015.11287.

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We investigated the effect of Cu alloying on S poisoning of Ni surfaces and nanoparticle morphologies using ab-initio thermodynamics calculations. Based on the Cu segregation energy and the S adsorption energy, the surface energy and nanoparticle morphology of pure Ni, pure Cu, and NiCu alloys were evaluated as functions of the chemical potential of S and the surface orientations of (100), (110), and (111). The constructed nanoparticle morphology was varied as a function of chemical potential of S. We find that the Cu added to Ni for NiCu alloys is strongly segregated into the top surface, and increases the S tolerance of the NiCu nanoparticles.
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Zhu, Chunxiao, Hugh Daigle i Steven L. Bryant. "Paramagnetic nanoparticles as nuclear magnetic resonance contrast agents in sandstone: Importance of nanofluid-rock interactions". Interpretation 4, nr 2 (1.05.2016): SF55—SF65. http://dx.doi.org/10.1190/int-2015-0137.1.

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Nuclear magnetic resonance has been applied in well logging to investigate pore size distribution with high resolution and accuracy based on the relaxation time distribution. However, due to the heterogeneity of natural rock, pore surface relaxivity, which links relaxation time and pore size, varies within the pore system. To analyze and alter pore surface relaxivity, we saturated Boise sandstone cores with positively charged zirconia nanoparticle dispersions in which nanoparticles can be adsorbed onto the sandstone pore wall, while negatively charged zirconia nanoparticles dispersions were used as a control group to provide the baseline of nanoparticle retention due to nonelectrostatic attraction. We have performed core flushing with deionized water, pure acid, and alkali with different pH values; compared properties of zirconia nanoparticles before and after exposure to Boise sandstone; analyzed the portion of zirconia nanoparticles retained in the rock; altered pore surface relaxivity; and linked the adsorbed nanoparticle concentration on the pore surface to the modified surface relaxivity. Our work has indicated that after two pore volumes of core flooding, there was approximately 1% of negatively charged nanoparticles trapped in the Boise sandstone core, whereas approximately 8%–11% of positively charged nanoparticles was retained in the Boise sandstone cores. Our results indicated that besides van der Waals attraction, electrostatic attraction was the driving force for retention of nanoparticles with a positive surface charge in sandstone cores. The attachment of nanoparticles onto sandstone surfaces changed the mineral surface relaxivity. Exposure to acidic or strong alkaline conditions increased the Boise sandstone surface relaxivity. After contact with Boise sandstone, the nanoparticles themselves exhibited increased relaxivity due to interactions between nanoparticles dispersion and mineral surface under different pH conditions.
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Xu, Chang, Albert Wan, Xianchang Gong, N. V. S. Dinesh K. Bhupathiraju, James D. Batteas i Charles Michael Drain. "Reorganization of porphyrin nanoparticle morphology driven by surface energetics". Journal of Porphyrins and Phthalocyanines 20, nr 01n04 (styczeń 2016): 438–43. http://dx.doi.org/10.1142/s1088424616500292.

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Organic nanoparticles (ONp) of an Fe(III) porphyrin appended with four [Formula: see text]-polyethyleneglyco-pyridinium moieties prepared in acetonitrile were deposited onto hydrophilic or hydrophobic Si surfaces. Self-organized by intermolecular interactions, ONp reorganize in response to environmental changes. Mechanisms for the control of nanoparticle morphologies and surface patterning by varying surface energies are discussed.
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Rozprawy doktorskie na temat "Nanoparticle Surface"

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Hoff, Richard. "Iron Oxide Nanoparticle Surface Modification: Synthesis and Characterization". Master's thesis, Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/592997.

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Bioengineering
M.S.
Multifunctional nanomaterials can be engineered to aid in the diagnosis of diseases, enable efficient drug delivery, monitor treatment progress over time, and evaluate treatment outcomes. This strategy, known as theranostics, focuses on the combination of diagnostic and therapeutic techniques to provide new clinically safe and efficient personalized treatments. The evaluation of different nanomaterials’ properties and their customization for specific medical applications has therefore been a significant area of interest within the scientific community. Iron oxide nanoparticles, specifically those based on iron (II, III) oxide (magnetite, Fe3O4), have been prominently investigated for biomedical, theranostic applications due to their documented superparamagnetism, high biocompatibility, and other unique physicochemical properties. The aim of this thesis is to establish a viable set of methods for preparing magnetite (iron oxide) nanoparticles through hydrothermal synthesis and modifying their surfaces with organic functional groups in order to both modulate surface chemistry and facilitate the attachment of molecules such as peptides via covalent bond formations. Modifying their surfaces with biomolecules such as peptides can further increase their uptake into cells, which is a necessary step in the mechanisms of their desired biomedical applications. The methods of nanoparticle synthesis, surface functionalization, and characterization involving electron microscopy (e.g., SEM, TEM), zeta potential measurements, size analysis (i.e., DLS), and FT-IR spectroscopy will be presented.
Temple University--Theses
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D'ALICARNASSO, MARCO. "SURFACE FUNCTIONALIZED GOLD NANOPARTICLES AS ATTACHMENT INHIBITORS FOR HEPARAN SULFATE-BINDING VIRUSES". Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/366392.

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Infectious diseases account for one fifth of global mortality. Although many efforts have been made to prevent and treat specific viral diseases (e.g. hepatitis B, AIDS) with vaccines and drugs, we still lack effective and biocompatible broad-spectrum antiviral agents, especially against re-emerging (e.g. Dengue virus) and newly emerging viruses (e.g. Ebola virus). Current advances in nanotechnology opened new frontiers in developing novel antivirals that can interact and inactivate a large number of viral pathogens. Nanoparticles (NPs) – particles in the size range 1-100 nm – can be finely engineered on their surface to interfere with key events of infections shared by many viruses, above all the attachment to the host cell. The aim of the present work is to assess the role of gold nanoparticles (Au- NPs) capped with sulfonate molecules as potential inhibitors toward human viruses binding sulfated polysaccharides on the cell membrane. Results showed that sulfonated NPs have powerful antiviral as well as virucidal activity. Their applications may lead to substantial improvements in virus-spread control not only as novel wide-spectrum therapeutic agents but most importantly as novel active materials to be employed in emergency situations, for example in personal protective equipment, waste management, virus containment.
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Brazzale, Chiara. "Gold nanoparticle surface tuning for multimodal treatment of cancer". Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424441.

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In the last decades colloidal decorated gold nanoparticles (GNPs) have been studied as platform for drug and gene delivery, for diagnostic and other biomedical applications. These metal nanoparticles are intriguing because of their unique physico-chemical properties that can be exploited for multimodal and combined treatment of cancer. In the present thesis work gold nanoparticles were decorated with a targeting ligand (Folate-PEG) to combine an active and a passive targeting aiming to enhance the selective accumulation within the tumour site. Deep studies have been done to investigate the effect of surface Folate density on the internalization efficiency of gold nanoparticles. Afterwards intracellular trafficking studies were performed to clarify the uptake mechanism and investigate lysosomal delivery. Confocal microscopy and TEM analysis showed in good agreement that Folate targeted gold nanoparticles are internalized via a clathrin-independent pathway. Another purpose of the project have concerned the exploitation of GNPs as sensitizers in the sonodynamic therapy. This is a non-invasive approach which consists in cancer tissue irradiation with focused ultrasounds (HIFU) to trigger cavitation phenomena leading to irreversible destruction of the target tissue. The combination of the ultrasound exposure and the pre-incubation of cells with Folate targeted particles induced a significant and selective cell death. The concept of multimodal targeting was extended to the development of pH responsive targeted gold nanoparticles, using a pH sensitive polymer able to respond with morphological alterations to environmental pH changes. The cell uptake results confirmed that the “hiding” and “reveal” of targeting agents on GNP surface is modulated by the sensitive polymer. As a result there is an enhanced site-selective GNP accumulation in the cancer tissue, according to a cooperative exploitation of phenotypic and environmental features of the tumour. In conclusion, the present thesis work is proposed as proof-of-concept to show that by finely tuning the surface properties of nanosystems, site-selectivity can be significantly enhanced, thus reducing the disposition of drug nanocarriers in off-target tissues.
Lo scopo del presente progetto di dottorato è stato quello di produrre e caratterizzare dal punto di vista chimico-fisico e biologico un nanocarrier per il direzionamento selettivo di farmaci antitumorali a tumori sovraesprimenti il recettore per l’acido folico. Sono stati compiuti studi approfonditi per verificare come la densità dell’agente di targeting influenzasse l’efficienza d’internalizzazione del sistema. Inoltre studi di trafficking intracellulare hanno verificato come particelle d’oro direzionate con agente di targeting Folato-PEG vengano internalizzate mediante meccanismo clatrina-indipendente. Si è inoltre indagata la capacità di nanoparticelle d’oro come sensibilizzanti alla terapia sonodinamica al fine di poter combinare un trattamento farmacologico ad un approccio fisico. Un ulteriore sviluppo del progetto ha riguardato la modifica di nanoparticelle d’oro direzionate con Folato-PEG con una seconda componente pH responsiva in grado di passare da una conformazione estesa a pH fisiologico di 7.4 ad una forma idrofobica globulare a pH 6.5, condizione tipica del tessuto tumorale. In questo modo é possibile modulare il mascheramento/esposizione dell’agente di targeting e ridurre il bio-riconoscimento aspecifico a favore della sito-specificità. Tra gli sviluppi futuri del progetto, vi è la decorazione di nanoparticelle d’oro con un polimero dotato di gruppi idrazinici coniugati a Doxorubicina mediante legame idrazonico. In virtù delle proprietà del legame idrazonico, la Doxorubicina sarà rilasciata esclusivamente nei comparti endosomiali e lisosomiali, in seguito all'uptake cellulare mediato dal recettore FR per l’acido folico.
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Thorn, Angie Sue (Morris). "The impact of nanoparticle surface chemistry on biological systems". Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5659.

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The unique properties of nanomaterials, such as their small size and large surface area-to-volume ratios, have attracted tremendous interest in the scientific community over the last few decades. Thus, the synthesis and characterization of many different types of nanoparticles has been well defined and reported on in the literature. Current research efforts have redirected from the basic study of nanomaterial synthesis and their properties to more application-based studies where the development of functionally active materials is necessary. Today such nanoparticle-based systems exist for a range of biomedical applications including imaging, drug delivery and sensors. The inherent properties of the nanomaterial, although important, aren’t always ideal for specific applications. In order to optimize nanoparticles for biomedical applications it is often desirable to tune their surface properties. Researchers have shown that these surface properties (such as charge, hydrophobicity, or reactivity) play a direct role in the interactions between nanoparticles and biological systems can be altered by attaching molecules to the surface of nanoparticles. In this work, the effects of physicochemical properties of a wide variety of nanoparticles was investigated using in vitro and in vivo models. For example, copper oxide (CuO) nanoparticles were of interest due to their instability in biological media. These nanoparticles undergo dissolution when in an aqueous environment and tend to aggregate. Therefore, the cytotoxicity of two sizes of CuO NPs was evaluated in cultured cells to develop a better understanding of how these propertied effect toxicity outcomes in biological systems. From these studies, it was determined that CuO NPs are cytotoxic to lung cells in a size-dependent manner and that dissolved copper ions contribute to the cytotoxicity however it is not solely responsible for cell death. Moreover, silica nanoparticles are one of the most commonly used nanomaterials because they are easy to synthesize and their properties (such as size, porosity and surface chemistry) can be fine-tuned. Silica nanoparticles can be found in thousands of commercially available products such as toothpastes, cosmetics and detergents and are currently being developed for biomedical applications such as drug delivery and biomedical imaging. Our findings herein indicate that the surface chemistry of silica nanoparticles can have an effect on lung inflammation after exposure. Specifically, amine-modified silica NPs are considered to be less toxic compared to bare silica nanoparticles. Together, these studies provide insight into the role that material properties have on toxicity and allow for a better understanding of their impact on human and environmental health. The final aim of this thesis was to develop surface-modified nanoparticles for drug delivery applications. For this, biodegradable, polymeric NPs were used due to their inert nature and biocompatibility. Furthermore, polymeric NPs are excellent for loading drugs and using them as drug delivery vehicles. In this work, poly (lactic-co-glycolic acid) (PLGA) NPs were loaded with a therapeutic peptide. These NPs were then coated with chitosan (a mucoadhesive polymer) for the treatment of allergic asthma or coated with a small cationic mitochondrial targeting agent for the treatment of ischemia/reperfusion injury. Taken as a whole, this thesis sheds light on the impact of NPs on human health. First by providing useful toxological data for CuO and silica NPs as well as highlighting the potential of surface-modified polymeric NPs to be used in drug delivery-based applications.
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Dolci, Mathias. "Design of magnetic iron oxide nanoparticle assemblies supported onto gold thin films for SPR biosensor applications". Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAE001/document.

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La bio-détection de molécules reposant sur le phénomène de résonnance plasmon permet de détecter des espèces en utilisant les propriétés optiques de films métalliques. L’utilisation de ce type de capteurs nécessite néanmoins l’augmentation de leurs performances afin de détecter des concentrations faibles d’analyte dans des milieux complexes. L’assemblage de nanoparticules d’oxyde de fer sur des substrats d’or, en utilisant des groupements complémentaires spécifiques via la méthode de chimie « click », permet de contrôler leur distribution spatiale à la surface du substrat. Les propriétés magnétiques portées par les nanoparticules sont ainsi étudiées en fonction de leurs distances inter-particules ainsi que de leurs tailles. Par ailleurs, le plasmon de surface du substrat étant directement influencé par l’assemblage des nanoparticules, il sera possible de contrôler la sensibilité du capteur pour étudier la détection de différentes biomolécules impliquées dans des processus biologiques. La présence des nanoparticules augmente les propriétés optiques intrinsèques de la surface du substrat et la géométrie de l’assemblage permet d’augmenter la quantité de biomolécules détectées
Biomolecular detection based on the surface plasmon resonance phenomenon allow detecting species by using the optics properties of metallic thin films. This kind of biosensors require the increase of their performances in order to detect low concentration analyte in complex medium. The assembly of iron oxide nanoparticles on gold substrates by using specific complementary groups via the “click” chemistry technique allows controlling their spatial distribution on the substrate surface. The magnetic properties carried by the nanoparticles are studied as function of their inter-particle distances and their sizes. Moreover, the surface plasmon of the substrate is directly influenced by the nanoparticle assembly and the control of the sensor sensitivity will be possible in order to study the detection of different biomolecules implies in biological processes. The presence of nanoparticles increases the intrinsic optical properties at the substrate surface and the geometry of the assembly allow increasing the number of biomolecules detected
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Ranjan, Rajesh. "Surface Modification of Silica Nanoparticles". University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1206558086.

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Jayalath, Mudiyanselage Sanjaya Dilantha. "Surface adsorption of natural organic matter on engineered nanoparticles". Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6440.

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Nanoparticles have gained growing attention of the scientific community over the past few decades due to their high potential to be used in diverse industrial applications. Nanoparticles often possess superior characteristics, such as catalytic activity, photochemical activity, and mechanical strength, compared to their bulk counterparts, making them more desirable in different industrial applications. During the past few decades, the use of the nanoparticles in various industries has been increased. With increasing usage release of nanoparticles into the environment has also increased. There is a growing concern about the nanoparticle toxicity and numerous studies have shown the toxic effects of different nanoparticles on various plants, animals, and microorganisms in the environment. Toxicity of nanoparticles is often attributed to their morphology and their ability to undergo different transformations in the environment. These transformations include aggregation, dissolution, and surface adsorption. Natural organic matter (NOM) are the most abundant natural ligands in the environment which include Humic acid and Fulvic acid. These high molecular weight organic molecules have complex structures and contain many different functional groups such as carboxylic acid groups, hydroxyl, amino and phenolic groups that can interact with the nanoparticle surface. The nature and the intensity of the interaction are dependent on several factors including the size and the surface functionality of nanoparticles and pH of the medium. The smaller the nanoparticle, the higher the adsorption of NOM due to the high surface to volume ratio of smaller particles. Functional groups on the surface dictate the surface charge of the nanoparticles in water depending on the acidity. The higher the acidity, higher the adsorption of NOM due to increased electrostatic attractions between positively charged nanoparticles and the negatively charged NOM molecules. Adsorbed NOM on nanoparticles affect the other transformations such as aggregation and dissolution and can in turn alter the reactivity and toxicity of the nanoparticles. Therefore, effect of NOM is an important factor that should be considered in environmental toxicity related studies of nanoparticles.
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Kulkarni, Amit. "Surface Modification of Carboxyl-functionalized Polymeric Nanoparticles for Attachment of Targeting Peptides". University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1242986910.

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Austin, Lauren Anne. "Exploring some aspects of cancer cell biology with plasmonic nanoparticles". Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/54236.

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Plasmonic nanoparticles, specifically gold and silver nanoparticles, exhibit unique optical, physical, and chemical properties that are exploited in many biomedical applications. Due to their nanometer size, facile surface functionalization and enhanced optical performance, gold and silver nanoparticles can be used to investigate cellular biology. The work herein highlights a new methodology that has exploited these remarkable properties in order to probe various aspect of cancer cell biology, such as cell cycle progression, drug delivery, and cell death. Cell death mechanisms due to localized gold and silver nanoparticle exposure were also elucidated in this work. Chapter 1 introduces the reader to the synthesis and functionalization of gold and silver nanoparticles as well as reviews their implementation in biodiagnostic and therapeutic applications to provide a foundation for Chapters 3 and 4, where their use in spectroscopic and cytotoxic studies are presented. Chapter 2 provides the reader with detailed explanations of experimental protocols for nanoparticle synthesis and functionalization, in vitro cellular biology experiments, and live-cell Raman spectroscopy experiments that were utilized throughout Chapters 3 and 4. Chapter 3 presents the use of nuclear-targeted gold nanoparticles in conjunction with a Raman microscope modified to contain a live-cell imaging chamber to probe cancer cell cycle progression (Chapter 3.1), examine drug efficacy (Chapter 3.2), monitor drug delivery (Chapter 3.3), and detect apoptotic molecular events in real-time (Chapter 3.4). In Chapter 4, the intracellular effects of gold and silver nanoparticles are explored through live-cell Rayleigh imaging, cell cycle analysis and DNA damage (Chapter 4.1), as well as through the elucidation of cytotoxic cell death mechanisms after nanoparticle exposure (Chapter 4.2) and live cell imaging of silver nanoparticle treated cancer cell communities (Chapter 4.3).
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Nguyen, Van Bac. "Prédiction des morphologies de nanoparticules métalliques à partir de calculs DFT des interactions surface-ligand". Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30299/document.

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Les nanoparticules (NPs) sont des matériaux fonctionnels importants du fait de leur taille nanométrique. Cette réduction en taille, associée à la composition, à l'orientation des surfaces et à la morphologie contribue à l'exaltation de nombreuses propriétés importantes telles que les propriétés électroniques, magnétiques, catalytiques, optiques, etc. Pour contrôler la morphologie des NPs, de nombreux efforts ont été consacrés à comprendre leurs mécanismes de formation et l'origine de leur stabilité. Parmi les nanoparticules métalliques, le cobalt, avec sa structure hexagonale compact (hcp), est particulièrement intéressant pour la possibilité d'obtenir des nanocristaux de forme "naturellement" anisotropique. Par synthèse chimique en milieu liquide, des NPs de différentes morphologies telles que des disques, des plaques, des bâtonnets, des fils et des cubes ont été obtenues en contrôlant le type de précurseur, de l'agent réducteur, des ligands stabilisants, ainsi que la concentration de ces ligands, la température ou la vitesse d'injection des précurseurs. Même si ces conditions de synthèse ont été rationalisées, les mécanismes à l'origine de ces différentes morphologies ne sont pas encore bien connus. Dans ce travail, nous avons développé deux modèles quantitatifs pour la prédiction de la morphologie, l'un est basé sur l'équilibre thermodynamique de l'état final, et l'autre sur un contrôle par l'effet cinétique. Pour appliquer ces modèles, il a été nécessaire de calculer dans un premier temps, avec la théorie de la fonctionnelle de la densité (DFT), les comportements d'adsorption des molécules ligands en fonction du taux de recouvrement sur les facettes de différentes orientations du métal. Pour ce faire, l'adsorption des ligands CH 3 NH 2 , CH 3 COO, C 5 H 11 COO et C 11 H 23 COO a été modélisée sur les différentes surfaces de Co et de Ni. La morphologie des NPs de Co prédite par ces deux modèles a été comparée à celles obtenues expérimentalement et à d'autres résultats théoriques de la littérature. La variété des formes obtenues par le modèle cinétique semblerait mieux correspondre aux NPs synthétisées avec les différentes conditions expérimentales. Ceci confirme que la morphologie des NPs est guidée avant tout par un effet cinétique
Nanoparticles are one of the most important families of functional materials due to their nanometric size. This size reduction, associated to their composition, surfaces orientation and morphology has contributed to the emergence of new important properties such as electronic, magnetic, catalytic, optic, etc. To control the morphology of NPs, many efforts have been devoted to understand their formation mechanism and the origin of their stability. Among metallic nanoparticles, cobalt, with its hexagonal closed-packed (hcp) structure, is particularly interesting because of the possibility to grow "naturally" anisotropic shaped nanocrystals. Using chemical synthesis in liquid environment, various morphologies such as disks, plates, rods, wires and cubes have been obtained by controlling the precursor type, the reducing agent, the stabilizing ligands as well as their concentration, the temperature or the rate of precursor injection. Even if these synthesis conditions have been rationalized, few is known concerning the growth mechanisms at the atomic scale. In this work, we have developed two quantitative morphology prediction models, one based on the final thermodynamic equilibrium state, while another is controlled by the kinetics. These models require the knowledge of the adsorption behaviors of stabilizing molecules as a function of surface coverage on preferential facets of NPs. To this end, density functional theory (DFT) calculations were performed on a series of stabilizing molecules (CH3NH2 , CH3COO C5H11OO and C11H23COO) adsorbed on the different Co and Ni surfaces. The shape of the Co NPs obtained by these two models was compared to experimental morphologies and other theoretical results from the literature. The variety of forms predicted by the kinetic model agrees better with the NPs morphologies obtained under the different synthesis conditions. This confirms that the morphology control of NPs is mostly driven by the kinetics
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Książki na temat "Nanoparticle Surface"

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1945-, Więckowski Andrzej, Savinova Elena R. 1950- i Vayenas C. G, red. Catalysis and electrocatalysis at nanoparticle surfaces. New York: Marcel Dekker, 2003.

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Mittal, Vikas, red. Surface Modification of Nanoparticle and Natural Fiber Fillers. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2015. http://dx.doi.org/10.1002/9783527670260.

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Wang, Jianpeng. Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-53399-4.

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Marie-Isabelle, Baraton, red. Synthesis, functionalization and surface treatment of nanoparticles. Stevenson Ranch, Calif: American Scientific Publishers, 2003.

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1943-, Schwarz James A., i Contescu Cristian I. 1948-, red. Surfaces of nanoparticles and porous materials. New York: Marcel Dekker, 1999.

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H, Fendler Janos, Dékány Imre, North Atlantic Treaty Organization. Scientific Affairs Division. i NATO Advanced Research Workshop on Nanoparticles in Solids and Solutions--an Integrated Approach to Their Preparation and Characterization (1996 : Szeged, Hungary), red. Nanoparticles in solids and solutions. Dordrecht: Kluwer Academic Publishers, 1996.

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Fiorani, Dino, red. Surface Effects in Magnetic Nanoparticles. Boston, MA: Springer US, 2005. http://dx.doi.org/10.1007/b136494.

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Media, Springer Science+Business, red. Surface effects in magnetic nanoparticles. New York: Springer, 2005.

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Advanced polymer nanoparticles: Synthesis and surface modifications. Boca Raton: Taylor & Francis, 2011.

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Characterization & control of interfaces for high quality advanced materials: Proceedings of the International Conference on the Characterization and Control of Interfaces for High Quality Advanced Materials (ICCCI 2003), Kurashiki, Japan, 2003. Westerville, OH: American Ceramic Society, 2005.

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Części książek na temat "Nanoparticle Surface"

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Wang, Yuling, i Erkang Wang. "Nanoparticle SERS Substrates". W Surface Enhanced Raman Spectroscopy, 39–69. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527632756.ch2.

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Seibert, A., S. Stumpf, T. Gouder, D. Schild i M. A. Denecke. "Actinide Thin Films as Surface Models". W Actinide Nanoparticle Research, 275–313. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11432-8_10.

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Khetani, Altaf, Ali Momenpour, Vidhu S. Tiwari i Hanan Anis. "Surface Enhanced Raman Scattering (SERS) Using Nanoparticles". W Silver Nanoparticle Applications, 47–70. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-11262-6_3.

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Webster, Linden R., K. Suhling i D. Richards. "Single Nanoparticle Surface Enhanced Fluorescence". W NATO Science for Peace and Security Series B: Physics and Biophysics, 457–58. Dordrecht: Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5313-6_60.

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Xie, Jin, Jinhao Gao, Mark Michalski i Xiaoyuan Chen. "Nanoparticle Surface Modification and Bioconjugation". W Nanoplatform-Based Molecular Imaging, 47–73. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9780470767047.ch3.

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Huh, Chun, Hugh Daigle, Valentina Prigiobbe i Maša Prodanović. "Nanoparticle Synthesis and Surface Coating". W Practical Nanotechnology for Petroleum Engineers, 13–44. Boca Raton : Taylor & Francis a CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa, plc, 2019.: CRC Press, 2019. http://dx.doi.org/10.1201/9781351210362-2.

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Schlücker, Sebastian. "SERS Microscopy: Nanoparticle Probes and Biomedical Applications". W Surface Enhanced Raman Spectroscopy, 263–83. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527632756.ch12.

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Iglesias, Òscar, i Hamid Kachkachi. "Single Nanomagnet Behaviour: Surface and Finite-Size Effects". W New Trends in Nanoparticle Magnetism, 3–38. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-60473-8_1.

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Oliveira, M. M., D. Zanchet, D. Ugarte i A. J. G. Zarbin. "Synthesis and characterization of silver nanoparticle/polyaniline nanocomposites". W Surface and Colloid Science, 126–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b97108.

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Boulmer-Leborgne, Chantal, Ratiba Benzerga i Jacques Perrière. "Nanoparticle Formation by Femtosecond Laser Ablation". W Laser-Surface Interactions for New Materials Production, 125–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03307-0_6.

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Streszczenia konferencji na temat "Nanoparticle Surface"

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Rajendran, Silambarasan. "Consequence of Nanoparticle Physiognomies on Heat Transfer Characteristics of Heat Exchanger". W International Conference on Advances in Design, Materials, Manufacturing and Surface Engineering for Mobility. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2020. http://dx.doi.org/10.4271/2020-28-0462.

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<div class="section abstract"><div class="htmlview paragraph">In this paper the heat transfer coefficient and the heat transfer rate of a heat exchanger is scrutinized by using nanofluids. The silicon carbide nanoparticles, milled and sonificated as nanofluids of volume fractions 0.01499(%) and 0.01399(%). The heat transfer characteristics of SiC(P)/water, SiC(M)/water, SiC(P)/EG, SiC(M)/EG are measured in a concentric tube heat exchanger under laminar flow condition. The consequence of nanoparticle physiognomies, Reynolds number, on the heat transfer characteristic is scrutinized. It has been found that the addition of milled nanoparticlein the base fluids enhances the heat transfer characteristics rather than the normal nanoparticle. The experimental results shows that the heat transfer characteristics of SiC(M) is higher than that of SiC(P) in both the case of water and EG. This is because of the structural changes of SiC-M by the deformation caused by the ball milling.</div></div>
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Pilch, Iris, Nils Brenning, Ulf Helmersson i Daniel Söderström. "High Power Pulsed Hollow Cathode for Nanoparticle Synthesis". W 13th International Conference on Plasma Surface Engineering September 10 - 14, 2012, in Garmisch-Partenkirchen, Germany. Linköping University Electronic Press, 2013. http://dx.doi.org/10.3384/wcc2.118-121.

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Copper nanoparticles were synthesized using a novel method based on sputtering material from a hollow cathode using high power pulses. The high power pulses provide a supersaturated vapor with a high degree of ionization from which the nanoparticles are formed in the gas phase. By adjusting the pulse parameters, the plasma environment and thus the nanoparticle growth can be affected. It was found that the nanoparticle size can be influenced by varying, e.g., the pulse frequency or the pulse power. The results using the high power pulsed hollow cathode are compared to nanoparticles synthesized with a dc discharge using the same setup.
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Zhang, Feini, i Anthony M. Jacobi. "Metal Surface Wettability Manipulation by Nanoparticle Deposition During Nanofluid Boiling". W ASME 2015 13th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2015 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/icnmm2015-48687.

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Surface wettability of materials is important in heat transfer and thermal processes at micro-scale. This paper presents the manipulation of metal surface wettability by nanofluid boiling nanoparticle deposition. As confirmed by microscopy, particles can be deposited on metal surfaces by boiling in nanoparticle suspension, which significantly enhanced the surface wettabiliy relative to that of its original condition. The change in wettability is coupled to boiling conditions, such as nanoparticle concentration, heat flux, boiling duration, substrate roughness and so on. It has been observed that the higher the concentration of nanoparticles in the liquid during the boiling deposition process, the more pronounced the impact on wetting. Hence, surface wettability can be manipulated by controlling the nanoparticle concentration during the nanofluid boiling nanoparticle deposition (NBND) process. Such method can potentially be applied to enhance the heat transfer performance in thermal devices.
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Kim, Seontae, Hyungmo Kim, Hyung Dae Kim, Ho Seon Ahn, Moo Hwan Kim, Joonwon Kim i Goon-Cherl Park. "Experimental Investigation of Critical Heat Flux Enhancement by Micro/Nanoscale Surface Modification in Pool Boiling". W ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2008. http://dx.doi.org/10.1115/icnmm2008-62289.

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Nanofluids, which contain uniformly and stably dispersed nanoparticles, exhibit an abnormal enhancement of the critical heat flux (CHF) when used as a working fluid in pool boiling. It has recently been demonstrated that optimal CHF enhancement in nanofluids is attained by the significant deposition of nanoparticles on the heater surface during pool boiling. The surface deposition of oxidized metal nanoparticles significantly enhances the wettability, and fractal micro/nanostructures formed by nanoparticle deposition induce liquid suction due to capillary wicking. It is supposed that the superior wettability and capillary wicking of the nanoparticle-fouled surface enhances CHF by promoting the dry patches to be effectively rewetted during the boiling process. In this regard, the excellent CHF performance of the nanoparticle-deposited surface can be reproduced using artificial structures via innovative surface-modification methods that yield good wettability and capillarity. To accomplish this goal, we plan to design and fabricate various artificial micro/nano-structured surfaces with good surface wettability and capillarity, and investigate their CHF performance. In the present study, we examined experimentally the CHF performances of a series of surface-modified samples (plane, micro-structured, nano-structured, and micro/nano structured surfaces). Pool boiling heat transfer of pure water on sample surfaces was investigated under atmospheric conditions. The CHF increase due to artificial surface modification is discussed based on solid-liquid interfacial parameters (static contact angle, roughness) that are closely related to CHF phenomenon in pool boiling.
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Chang, Sehoon, Shannon L. Eichmann i Wei Wang. "Nanoparticle Tracers in Reservoir-On-A-chip by Surface-Enhanced Raman Scattering - Fluorescence SERS-SEF Imaging Technology". W SPE Middle East Oil & Gas Show and Conference. SPE, 2021. http://dx.doi.org/10.2118/204704-ms.

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Abstract Nanoparticles or nanocomposite fluids are injected into oil reservoirs for reservoir tracing or to improve injectivity or recovery of oil. Effective application of nanoparticles in fluid flooding still needs to be investigated. Dual-mode surface-enhanced Raman scattering (SERS) - surface-enhanced fluorescence (SEF) composite nanoparticles have been developed as nanoparticle reservoir tracers. This presentation discusses their transport and detectability in porous media, providing valuable information for understanding the role of nanoparticles in EOR process. The dual-mode surface-enhanced Raman scattering (SERS) - surface-enhanced fluorescence (SEF) composite nanoparticles are synthesized composed of Ag or Au metal cores, specific dye molecules, and a SiO2 shell materials. To optimize maximum signal enhancement of both phenomena such as SERS and SEF, the distance between core metal nanoparticles and dye molecules are precisely controlled. The synthesized composite nanoparticles barcoded with dye molecules are detectable by both fluorescence and Raman spectroscopies due to the SERS-SEF phenomena. Both fluorescence and Raman microscopic images of dye embedded surfaceenhanced Raman scattering (SERS) surface-enhanced fluorescence (SEF) composite nanoparticles in water phase successfully were collected within microfluidic reservoir-on-a-chip. The reservoir-on-a-chip utilized in this study fabricated based on reservoir rock geometry and coated with calcium carbonate. The synthesized SERS-SEF composite nanoparticles in water solution have been flooded into the microfluidic reservoir-on-a-chip and imaged for probing interfacial behavior of fluids such as liquid-liquid interfaces and studying the behavior of nanoparticles at liquid-rock interfaces. The precise synthesis method to produce the composite nanoparticles has been developed for the embedded dye molecules to generate noticeably enhanced detectability due to the strong SERS phenomenon. In conclusion, SERS-SEF nanoparticles barcoded with the fingerprinted Raman and fluorescence signals can provide a possible pathway toward SERS-SEF nanoprobe as various barcoded tracers to understand fluid behavior in porous media. Composite nanoparticle synthesis and its detection in flow technologies have been developed for visualization of the fluid flow behavior in porous media representing reservoir rock geometry. The results of the high-resolution nanoparticle fluid imaging data in reservoir-on-a-chip can be applied to understand mechanism of nanoparticle fluid assisted chemical enhanced oil recovery.
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Lei, Yong, i Gerhard Wilde. "The UTAM Nano-Patterning: A New Surface Nano-Patterning Technique in Fabricating Ordered Arrayed Surface Nanostructures". W 2007 First International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2007. http://dx.doi.org/10.1115/mnc2007-21628.

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A new surface nano-patterning technique, the so-called UTAM nano-patterning approach, is reported here in this paper. Using the UTAM nano-patterning technique, large-scale arrays of highly ordered nanostructures (nanoparticles and nanoholes) in the range of square centimeters have been fabricated on substrates in a massive parallel way. The resulting nanostructures are characterized by highly defined and controllable size, shape, composition, and spacing of the nanostructures. By changing the structural parameters of the nanoparticles, the properties of the nanoparticle arrays can be tuned. This non-lithographic surface nano-patterning approach provides an efficient and low-cost alternative in fabricating large-scale ordered arrays of surface nanostructures.
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Alfakher, Ahmad M., i David A. DiCarlo. "Reduced Carbon Dioxide Mobility in Experimental Core Flood Using Surface Coated Silica Nanoparticles as a Foaming Agent". W Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32382-ms.

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Abstract Carbon dioxide (CO2) is the most used solvent in enhanced oil recovery (EOR), as it can have a high displacement efficiency in favorable conditions. Its disadvantages are relatively low sweep efficiencies caused by a viscosity and density that is lower than the fluid it displaces. Surface-coated silica nanoparticles create in-situ CO2 foam, which has a more favorable mobility ratio and therefore better sweep. These nanoparticles can also be used in carbon capture and storage (CCS) applications in injecting CO2 foam into brine aquifers. This paper presents the results of core flood experiments that aimed to study surface coated silica nanoparticles as an in-situ CO2 foaming agent. In these experiments, pressure drop was measured across the core as a whole and in five individual sections. The core was placed vertically, and liquid CO2 was pumped at the top of the core. Surface coated silica nanoparticles suspended in the brine is used in some of the floods and compared to a control flood that had no nanoparticles. In these experiments, pressure drops in nanoparticle cases were a multiple of 5-10 those in the control cases. In addition, total core pressure drops in nanoparticle cases increased as the core got more saturated with CO2, and the increase was observed sequentially in each section as it got invaded by CO2.The mobility of CO2 was reduced by an order of magnitude on average compared to the control. The CO2 moved slower through the core and breakthrough was delayed in the nanoparticle case. The study provides quantitative nanoparticle CO2foam mobility measurements and calculations, compared to those in control cases. Properties calculated from this study can be used to improve both EOR and CCS applications of CO2 flooding by scaling the results to the reservoir scale.
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Yinhua Lei, Wei Wang, Wengang Wu i Zhihong Li. "Surface charge sensitive suspended nanoparticle crystal". W 2010 Ninth IEEE Sensors Conference (SENSORS 2010). IEEE, 2010. http://dx.doi.org/10.1109/icsens.2010.5690975.

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Soni, Sanjeev, Himanshu Tyagi, Robert A. Taylor i Amod Kumar. "Effect of Nanoparticle Concentration on Thermal Damage in Nanoparticle-Assisted Thermal Therapy". W ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/mnhmt2016-6418.

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Photothermal therapy involving nanoparticles is evolving as a promising targeted treatment for cancer. This paper presents the results for the effect of nanoparticle concentration, within a tumor, to control the thermal damage during nanoparticle assisted thermal therapy. A surface tumor embedded with gold nanoparticles (distributed uniformly) is considered. The thermal damage is evaluated for various nanoparticle concentrations (within the tumor) to identify an optimal concentration of the nanoparticles so as to achieve spatial confinement of the damage to the tumor region. Optical interaction is coupled to the biological heat transfer through Pennes’ bioheat model and Beer’s law. Spatiotemporal thermal damage is simulated through the Arrhenius method. The finite difference implicit method is used to solve the coupled phenomenon. Results show that there is a specific value of nanoparticle concentration at which it is possible to confine thermal damage to the tumor within a spatial scale of less than 1 mm. This way the healthy tissues surrounding a tumor are safe. This optimum value of nanoparticle concentration (irrespective of tumor diameters) is 0.00001%. This concentration along with irradiation intensity of 1 W/cm2 for irradiation duration of 110 seconds is sufficient to thermally ablate the considered tumors. Novelty of this study is that it presents a combination of the controlling parameters for achieving a high (<1 mm) spatial confinement of the thermal damage. This finding is very much significant from clinical point of view. Clinically it is always desired to attain the therapeutic efficacy with minimal delivery of external agents (nanoparticles in this case) to a patient.
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Vafaei, Saeid, Dongsheng Wen, Ganapathiraman Ramanath i Theodorian Borca-Tasciuc. "Surface Wettability Through Asymptotic Contact Angle". W ASME 2009 Fluids Engineering Division Summer Meeting. ASMEDC, 2009. http://dx.doi.org/10.1115/fedsm2009-78361.

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The purpose of this investigation is to find a unique and accurate criterion to measure surface wettability. The asymptotic contact angle (droplet contact angle in no gravity condition), which is independent of droplet size, is used to identify the surface wettability in this work. The asymptotic contact angle is calculated by equating the normal component of interfacial force on an axisymmetric droplet and spherical droplet. The effect of 2.5 nm bismuth telluride nanoparticles on surface wettability is measured and evaluated by asymptotic contact angles as a sample. This paper also studies the effects of nanoparticles on solid, gas and liquid interactions at the triple line as well as the gas-liquid surface tension of aqueous solutions of 2.5 nm bismuth telluride nanoparticles functionalized with thioglycolic acid. Experimental measurements of nanofluid droplet shapes show that the contact angle strongly depends on nanoparticle concentrations. Fitting the droplet shape with predictions of the Laplace-Young equation, the nanofluid gas-liquid surface tension is determined.
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Raporty organizacyjne na temat "Nanoparticle Surface"

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Bratko, Dusan. Hydration Mechanisms in Nanoparticle Interaction and Surface Energetics. Office of Scientific and Technical Information (OSTI), sierpień 2020. http://dx.doi.org/10.2172/1648411.

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MYERS, Jr, SAMUEL M., DAVID M. FOLLSTAEDT i JAMES A. KNAPP. Surface Hardening by Nanoparticle Precipitation in Ni(Al,O). Office of Scientific and Technical Information (OSTI), kwiecień 2001. http://dx.doi.org/10.2172/780314.

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Ha, Ji Won. Single Molecule and Nanoparticle Imaging in Biophysical, Surface, and Photocatalysis Studies. Office of Scientific and Technical Information (OSTI), styczeń 2013. http://dx.doi.org/10.2172/1116723.

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Chefetz, Benny, Baoshan Xing i Yona Chen. Interactions of engineered nanoparticles with dissolved organic matter (DOM) and organic contaminants in water. United States Department of Agriculture, styczeń 2013. http://dx.doi.org/10.32747/2013.7699863.bard.

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Background: Engineered carbon nanotubes (CNTs) are expected to be increasingly released into the environment with the rapid increase in their production and use. The discharged CNTs may interact with coexisting contaminants and subsequently change environmental behaviors and ecological effects of both the CNTs themselves and the contaminants. Dissolved organic matter (DOM) plays a critical role in the transport of CNTs in the aquatic environment, affecting both CNT's surface properties through adsorption, and its colloidal stability in solution. Therefore, CNT-bound DOM complexes may interact with coexisting contaminants, thus affecting their environmental fate. With increasing production and use of CNTs, there is an increasing risk that humans could be exposed to CNTs mainly through ingestion and inhalation. Since CNTs can be carriers of contaminants due to their high adsorption affinity and capacity, the distribution of these nanoparticles in the environment holds a potential environmental and health risk. Project objectives: The overall goal of this project was to gain a better understanding of the environmental behavior of engineered nanoparticles with DOM and organic pollutant in aqueous systems. The scope of this study includes: characterizing various types of engineered nanoparticles and their interaction with DOM; binding studies of organic contaminants by nanoparticles and DOM-nanoparticle complexes; and examining interactions in DOM-nanoparticles-contaminant systems. Major conclusions, solutions and achievements: DOM has a pronounced effect on colloidal stability of CNTs in solution and on their surface chemistry and reactivity toward associated contaminants. The structure and chemical makeup of both CNTs and DOM determine their interactions and nature of formed complexes. CNTs, contaminants and DOM can co-occur in the aquatic environment. The occurrence of co-contaminants, as well as of co-introduction of DOM, was found to suppress the adsorption of organic contaminants to CNTs through both competition over adsorption sites and direct interactions in solution. Furthermore, the release of residual contaminants from CNTs could be enhanced by biomolecules found in the digestive as well as the respiratory tracts, thus increasing the bioaccessibility of adsorbed contaminants and possibly the overall toxicity of contaminant-associated CNTs. Contaminant desorption could be promoted by both solubilization and sorptive competition by biological surfactants. Scientific and agricultural implications: The information gained in the current project may assist in predicting the transport and fate of both CNTs and associated contaminants in the natural environment. Furthermore, the results imply a serious health risk from contaminant-associated CNTs.
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Choudhary, Ruplal, Victor Rodov, Punit Kohli, Elena Poverenov, John Haddock i Moshe Shemesh. Antimicrobial functionalized nanoparticles for enhancing food safety and quality. United States Department of Agriculture, styczeń 2013. http://dx.doi.org/10.32747/2013.7598156.bard.

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Original objectives The general goal of the project was to utilize the bactericidal potential of curcumin- functionalizednanostructures (CFN) for reinforcement of food safety by developing active antimicrobial food-contact surfaces. In order to reach the goal, the following secondary tasks were pursued: (a) further enhancement of the CFN activity based on understanding their mode of action; (b) preparing efficient antimicrobial surfaces, investigating and optimizing their performance; (c) testing the efficacy of the antimicrobial surfaces in real food trials. Background to the topic The project dealt with reducing microbial food spoilage and safety hazards. Cross-contamination through food-contact surfaces is one of the major safety concerns, aggravated by bacterial biofilm formation. The project implemented nanotech methods to develop novel antimicrobial food-contact materials based on natural compounds. Food-grade phenylpropanoidcurcumin was chosen as the most promising active principle for this research. Major conclusions, solutions, achievements In agreement with the original plan, the following research tasks were performed. Optimization of particles structure and composition. Three types of curcumin-functionalizednanostructures were developed and tested: liposome-type polydiacetylenenanovesicles, surface- stabilized nanoparticles and methyl-β-cyclodextrin inclusion complexes (MBCD). The three types had similar minimal inhibitory concentration but different mode of action. Nanovesicles and inclusion complexes were bactericidal while the nanoparticlesbacteriostatic. The difference might be due to different paths of curcumin penetration into bacterial cell. Enhancing the antimicrobial efficacy of CFN by photosensitization. Light exposure strengthened the bactericidal efficacy of curcumin-MBCD inclusion complexes approximately three-fold and enhanced the bacterial death on curcumin-coated plastic surfaces. Investigating the mode of action of CFN. Toxicoproteomic study revealed oxidative stress in curcumin-treated cells of E. coli. In the dark, this effect was alleviated by cellular adaptive responses. Under light, the enhanced ROS burst overrode the cellular adaptive mechanisms, disrupted the iron metabolism and synthesis of Fe-S clusters, eventually leading to cell death. Developing industrially-feasible methods of binding CFN to food-contact surfaces. CFN binding methods were developed for various substrates: covalent binding (binding nanovesicles to glass, plastic and metal), sonochemical impregnation (binding nanoparticles to plastics) and electrostatic layer-by-layer coating (binding inclusion complexes to glass and plastics). Investigating the performance of CFN-coated surfaces. Flexible and rigid plastic materials and glass coated with CFN demonstrated bactericidal activity towards Gram-negative (E. coli) and Gram-positive (Bac. cereus) bacteria. In addition, CFN-impregnated plastic material inhibited bacterial attachment and biofilm development. Testing the efficacy of CFN in food preservation trials. Efficient cold pasteurization of tender coconut water inoculated with E. coli and Listeriamonocytogeneswas performed by circulation through a column filled with CFN-coated glass beads. Combination of curcumin coating with blue light prevented bacterial cross contamination of fresh-cut melons through plastic surfaces contaminated with E. coli or Bac. licheniformis. Furthermore, coating of strawberries with CFN reduced fruit spoilage during simulated transportation extending the shelf life by 2-3 days. Implications, both scientific and agricultural BARD Report - Project4680 Page 2 of 17 Antimicrobial food-contact nanomaterials based on natural active principles will preserve food quality and ensure safety. Understanding mode of antimicrobial action of curcumin will allow enhancing its dark efficacy, e.g. by targeting the microbial cellular adaptation mechanisms.
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Chung, Po-Wen. Synthesis, characterization, and application of surface-functionalized ordered mesoporous nanoparticles. Office of Scientific and Technical Information (OSTI), styczeń 2009. http://dx.doi.org/10.2172/985161.

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Murphy, Catherine J. Nanoparticles and Nanostructured Surfaces: Novel Reporters with Biological Applications. Fort Belvoir, VA: Defense Technical Information Center, styczeń 2001. http://dx.doi.org/10.21236/ada409010.

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Choudhary, Ruplal, Victor Rodov, Punit Kohli, John D. Haddock i Samir Droby. Antimicrobial and antioxidant functionalized nanoparticles for enhancing food safety and quality: proof of concept. United States Department of Agriculture, wrzesień 2012. http://dx.doi.org/10.32747/2012.7597912.bard.

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General concept. The reported 1-year study tested the feasibility ofpreparing antimicrobial and antioxidant nanoparticlesfunctionalized with natural phenolic compounds, as a first step to reach the ultimate goal - improving safely and quality of foods by developing novel antimicrobial and antioxidant food-contacting materials. The secondary objectives of the study were (a) selecting the most promising phenoliccompounds, (b) building nanoparticles with the selected phenolicgrafted on their Surface, and (c) testing antimicrobial and antioxidant properties of these particles. The study was expected to provide a " go/no go" decision as concerning the prospects of phenolic- bound nanoparticles as antimicrobial and antioxidant agents. Results. In course of the feasibility study, curucminwas chosen as the most promising phenoliccompound due to its high antibacterial activity exceeding other tested compounds by at leas one order of magnitude. Lipsome-typephospholipid/polydiacetylene(PDA) nanoparticlesfunctionalizedwith curcuminwere successfully built. The pitfall of limited curcumin amount that could be covalently bound to theparticle surface was circumvented by inclusion of curcunun in the liposome body. It was suggested onthe basis of fluorescence spectroscopy that curcuminwas bound by hydrophobic forces in the bi1ayer periphery of the Liposomesand therefore mightexert a contact effect on microorganisms. The curcumin­ functionalizednanoparticles(CFN) were shown to have a strong bactericidal activity towards both Gram-negative (E. coli) and Gram-positive (B. ce,·e11s) bacteria, but only limited effect against yeast. Furthermore, beyond the originallyplanned objectives, preliminary trials showed that CFN could be bound to silanized glass surface rendering aנבtiנnicrobial activity to the glass. Tnaddition, the particles showed antioxidantcapacity. Tberefore, it ,vas co11cluded tlוattlוeaims of tlוefeasibility study bad been successfully reached an
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Marye Anne Fox, James K. Whitesell. Functionalized Nanoparticles and Surfaces for Controlled Chemical Catalysis and Effective Light Harvesting. Office of Scientific and Technical Information (OSTI), listopad 2012. http://dx.doi.org/10.2172/1054069.

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Yuwen, Jing. Polymer-Based Photoactive Surface for the Efficient Immobilization of Nanoparticles, Polymers, Graphene and Carbohydrates. Portland State University Library, styczeń 2000. http://dx.doi.org/10.15760/etd.413.

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