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Schroll, Ilse. "Genexpression während der Zahnentwicklung der Maus (Mus musculus)". Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-18423.
Pełny tekst źródłaSchroll, Ilse. "Genexpression während der Zahnentwicklung der Maus (Mus musculus) Literaturstudie /". [S.l.] : [s.n.], 2004. http://edoc.ub.uni-muenchen.de/archive/00001842.
Pełny tekst źródłaRinkwitz, Silke. "Molekulare Untersuchungen zur Innenohrmorphogenese bei der Maus (mus musculus)". [S.l. : s.n.], 1998. http://deposit.ddb.de/cgi-bin/dokserv?idn=955476097.
Pełny tekst źródłaManolakou, Ekaterini. "Etude multilocus d'interactions génomiques entre les sous-espèces "Mus musculus musculus" et "Mus musculus domesticus" à partir des croisements contrôlés". Montpellier 2, 1996. http://www.theses.fr/1996MON20136.
Pełny tekst źródłaDerothe, Jean-Marc. "Parasitisme et évolution hôte : approche expérimentale de la susceptibilité des hybrides entre les souris "Mus musculus musculus" et "Mus musculus domesticus"". Montpellier 2, 1999. http://www.theses.fr/1999MON20120.
Pełny tekst źródłaIvantcheva, Aglika. "Le rôle des mécanismes comportementaux dans l'isolement reproductif et la spéciation des souris sauvages "Mus musculus musculus", "Mus macedonicus" et "Mus spicilegus"". Montpellier 2, 1997. http://www.theses.fr/1997MON20026.
Pełny tekst źródłaOsterloh, Anke. "Hitzeschockprotein 60 (Hsp60) als immunologischer Signalverstärker in der Maus (Mus musculus)". [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976820706.
Pełny tekst źródłaJohnson, Maria Suzanne. "Limits to sustainable metabolic rate in Mus musculus". Thesis, University of Aberdeen, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265054.
Pełny tekst źródłaPaya-Cano, Jose Luis. "Functional genomics and cognitive performance in Mus musculus". Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417696.
Pełny tekst źródłaLafkas, Ginamarie N. "MicroRNA targeting in mus musculus and Caenorhabditis elegans". Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68432.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references (p. 45-52).
MicroRNAs (miRNAs) are small, approximately 22 nucleotide RNAs that regulate gene expression post-transcriptionally by base-pairing to complementary sites in the target mRNA. The first miRNA, lin-4, was discovered in 1993 in Caenorhabditis elegans; since then hundreds of miRNAs have been identified in C. elegans, Drosophila melanogaster, plants, mouse, and humans, where they approach a number equivalent to 1-2% of the protein-coding genes. With the exception of plants, miRNAs most commonly regulate targets by imperfectly pairing to 3' untranslated regions (UTRs), leading to translational repression or mRNA destabilization. The microRNA miR-196 is encoded at three paralogous locations in the HoxA, B, and C clusters in mammals and has conserved complementarity to the 3'UTRs of Hoxb8, Hoxc8, and Hoxa7; in particular, miR-1 96 has complete complementarity to Hoxb8 with the exception of a single G:U wobble. In 2004, Yekta et al., were able to detect RNA fragments diagnostic of miR-1 96-directed cleavage of Hoxb8 transcript in mouse embryos, and cell culture experiments showed down-regulation of Hoxb8, Hoxc8, Hoxd8, and Hoxa7. To address the biological significance of miR-196 mediated repression of Hox genes in vivo, we attempted to generate targeted transgenic mice for the Hoxa7, b8 and c8 genes. These mice would allow us to study the resulting phenotypic and molecular consequences and determine the impact this regulation has on establishment of the anterior-posterior axis in the developing embryo as well as its role in defining the expression boundaries of the individual Hox genes in vivo. The lin-4 miRNA plays a role in regulating the heterochronic genes involved in larval development in C. elegans. We used luciferase assays to test the efficacy of the seven proposed lin-4 binding sites in the lin-14 3'UTR and to determine if lin-4 is capable of recognizing and mediating repression through them. The wild-type lin-14 3'UTR was compared with mutant UTRs in which the lin-4 target sites were mutated. We determined that the three canonical 8mer sites are functional, as expected, and that at least one of the four additional sites is also recognized by lin-4 and contributes to the overall repression of the lin-14 3'UTR.
by Ginamarie N. Lafkas.
S.M.
Silva, Adriano Rios da. "Transmissão sexual do Trypanosoma cruzi em Mus musculus". reponame:Repositório Institucional da UnB, 2013. http://repositorio.unb.br/handle/10482/14829.
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A doença de Chagas é uma patologia que acomete milhares de pessoas no mundo inteiro, principalmente no continente Americano. O Trypanosoma cruzi, agente etiológico da doença de Chagas, é transmitido principalmente pelo inseto triatomíneo durante o repasto sanguíneo. Além da transmissão vetorial, a doença de Chagas pode ser adquirida por via transfusional, congenital ou pelo consumo de alimentos contaminados. A possibilidade da transmissão sexual da doença de Chagas foi sugerida por Carlos Chagas em 1909, entretanto, poucos trabalhos foram publicados sobre o tema desde então. O presente trabalho teve como objetivo investigar a transmissão sexual do Trypanossoma cruzi no modelo experimental murino. Para isso, foram feitos testes parasitológicos, sorológicos e moleculares em 20 camundongos infectados e em seus parceiros sexuais, inicialmente sadios. Os resultados mostraram que após o acasalamento com animais infectados, os parceiros sexuais apresentaram testes sorológicos positivos em 60% dos casos, enquanto que o DNA nuclear do parasito foi identificado no sangue dos animais analisados. Além disso, duas fêmeas inicialmente sadias apresentaram testes de hemocultura positivos após acasalarem com machos infectados, confirmando assim a trasmissão sexual do T. cruzi. Os resultados dos testes sorológicos e moleculares dos filhotes mostraram uma discrepância entre a sorologia e os resultados de PCR, sendo que o teste molecular apresentou uma maior sensibilidade. A taxa de infecção congênita obtida pelos métodos sorológicos revelaram que 14% dos filhotes provenientes dos Grupos A e B adquiriram a infecção, enquanto que o teste de PCR demonstrou uma positividade de 58%. A análise histopatológica não foi capaz de mostrar a presença de ninhos de amastigotas no coração dos animais infectados, tanto pela via intraperitonial, como pela via sexual. No entanto, pôde-se observar a presença de extenso infiltrado inflamatório destruindo as fibras cardíacas em todos os animais infectados. A análise de imunohistoquímica realizada em cortes histológicos de testículos de camundongos infectados revelou uma grande quantidade de formas amastigotas no túbulo seminífero e epidídimo. A capacidade de infecção do sêmem proveniente de indivíduo infectado pelo T. cruzi foi verificada. As análises histopatológicas mostraram a presença de ninhos de amastigotas no coração de fêmeas infectadas a partir da inoculação intra-vaginal de sêmen humano. Dessa forma, nossos resultados mostram que ocorreu transmissão sexual do Trypanosoma cruzi em camundongos.
Chagas disease is a condition that affects thousands of people worldwide, mainly in the Americas. Trypanosoma cruzi, etiologic agent of Chagas disease, is transmitted primarily by triatomine insect during blood feeding. Besides vetorial transmission, Chagas disease can be acquired by blood transfusion, congenital or by consumption of contaminated food. The possibility of sexual transmission of Chagas disease has been suggested by Carlos Chagas in 1909, however, few studies have been published on the subject since then. The present study aimed investigate sexual transmission of Trypanosoma cruzi in experimental murine model. For this, parasitological, serological and molecular infected mice and their sexual partners, initially healthy. The results showed that after mating with animals infected sexual partners serological tests showed positive in 60% of cases, while the nuclear DNA of the parasite was identified in blood from all animals analyzed. In addition, two healthy females initially showed positive blood culture tests after mating with infected males, thus confirming the sexually transmitted T. cruzi. The results of serological and molecular tests of pups showed a discrepancy between serology and PCR results, and the molecular test showed a higher sensitivity. Congenital infection rate obtained by serological methods showed that 14% of the from Groups A and B acquired infection, whereas the PCR test showed an 58% positivity. Histopathological analysis was not able to show the presence of nests of amastigotes in the hearts of infected animals, either by intraperitoneal as through sex. However, it was observed the presence of extensive inflammatory infiltrate destroying cardiac fibers in all infected animals. Immunohistochemical analysis performed in histological testis infected mice revealed a large amount of amastigotes in seminiferous tubule and epididymis. The ability of infection semen from individual infected with T. cruzi was verified. The histopathological analysis showed the presence of nests of amastigotes in the heart of infected females from intravaginal inoculation of human semen. Thus, our results show that there was sexual transmission of Trypanosoma cruzi in mice.
Barbosa, Luiz Gustavo Bicas. "Avaliação dos valores bromatológicos de camundongos (Mus musculus)". Botucatu, 2020. http://hdl.handle.net/11449/192879.
Pełny tekst źródłaResumo: Os camundongos (Mus musculus) atualmente compõem a base alimentar de diversas espécies animais, tanto mamíferos como aves e répteis. tendo assim certa importância para o manejo nutricional de animais de vida livre que necessitam de tratamento, por acidentes, tráfico, animais cativos em zoológicos e centros e triagens, e animais que são comercializados como pets exóticos. Este trabalho teve por objetivo fornecer uma base de informações de dieta em relação às necessidades nutricionais de animais que se alimentam de camundongos. Foi comparado o conteúdo nutricional de quatro grupos (G1, G2, G3, G4) de camundongos diferenciados por origem e tempo de congelamento. Cada grupo gerou um pool do qual mediu-se a composição centesimal (umidade, lipídios, proteínas, cinzas), calorimetria, os minerais: Sódio (Na), Potássio (K), Cálcio (Ca), Magnésio (Mg), Fósforo (P), Ferro (Fe), Manganês (Mn), Cobre (Cu), Selênio (Se), e Zinco (Zn) e feito o perfil de ácidos graxos. Observou-se diferença estatística quando a umidade e proteínas, e quanto a amostra in natura sem congelamento quando comparada com as amostras in natura congeladas. Os resultados apresentaram uma variação (p<0,001) entre os animais provindo de biotérios e de fonte comercial, mostrando divergência no padrão de qualidade, determinando pouca confiança dos valores nutricionais de animais adquiridos congelados de fonte comercial.
Abstract: Mice (Mus musculus) currently make up a food base for several animal species, both mammals, birds and reptiles. having the same importance for the nutritional management of free-living animals that can be treated, by accidents, trafficking, captive animals in zoos and centers and screens, and animals that are marketed as exotic pets. This work aimed to provide a base of information on diet in relation to the nutritional needs of animals that feed on mice. It was compared or nutritional content of four groups (G1, G2, G3, G4) of mice differentiated by origin and freezing time. Each group generated a pool of which type of chemical composition (composition, lipids, proteins, ash), calorimetry and minerals: Sodium (Na), Potassium (K), Calcium (Ca), Magnesium (Mg), Phosphorus (P), Iron (Fe), Manganese (Mn), Copper (Cu), Selenium (Se), and Zinc (Zn) and fat profile or profile. Observe the statistical difference when a molecule and proteins and how much a fresh sample are compared to frozen samples. The results showed a variation (p <0.001) between animals that come from biotechnology and commercial sources, showing divergence in the quality standard, determining little confidence in the nutritional values of animals purchased frozen from commercial sources.
Mestre
Solé, i. Canal Mireia. "Posicionament cromosòmic en cèl·lules de l’espermatogènesi de Mus musculus". Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/666890.
Pełny tekst źródłaChromosomes occupy specific regions of the nucleus called chromosome territories. In somatic cells, the positioning of the chromosomes is conditioned by gene density, transcriptional activity and the guanine-cytosine content. These associations demonstrate the existence of a functional relationship between chromosomal territoriality and gene expression. Little is known about chromosomal positioning during spermatogenesis. Some authors have suggested that the chromosomes distribution in spermatogenic cells could affect spermatogenesis development and have implications for embryo gene expression. The objective of this doctoral thesis was to establish a three-dimensional model of chromosomal territoriality during the different stages of the Mus musculus spermatogenesis. To achieve this objective, we have developed a methodology for performing three-dimensional study of chromosomes positioning in germ cells and spermatozoa with the aim to describe the chromosome positioning, and to identify the factors that regulate the territoriality of the chromosomes in these cell types. Testicular tissue from individuals of C57BL6J Mus musculus strain was used. The methodology developed consisted in the following procedures: i) optimized cell fixation to preserve the three-dimensionality of the nuclei, ii) fluorescence in situ hybridization of all mouse chromosomes, iii) three-dimensional image captures by confocal microscopy, iii) cell identification by immunofluorescence iv) image analysis using Matlab, v) numerical data extraction and statistical analysis. This methodology allowed the study of all chromosomes positioning of the mouse genome in five cellular stages, which cover the whole spermatogenic process: spermatogonia-early preleptotene, spermatocytes I at mid preleptotene-zygotene stages, spermatocytes I at pachytene stage, round spermatids and spermatozoa. For each stage, data of the nuclear volume occupied by each chromosome were obtained, the position of chromosomes according to the central-peripheral nuclear axis and the overlapping frequency between chromosomes. Results showed that radial and relative positioning of chromosomes during spermatogenesis is dynamic and non-random. Several evidences were observed indicating that the chromosomal events that lead to meiotic recombination determine the dynamics of homologue chromosomes position from spermatogonia to pachytene stage. In this sense, it has been observed that homologous chromosomes share the same chromosomal territory in stages near the beginning of meiosis. In addition, the bouquet distribution affects the territoriality organization of the nucleus at pachytene stage in accordance to chromosomal size, being the smallest chromosomes preferably observed in the nucleus periphery. On the other hand, several pieces of data suggest that gene activity is closely associated with the radial positioning of chromosomes throughout the spermatogenesis process. For instance, the nucleus interior presents a higher concentration of genetic material than the expected value. In addition, chromosomes with more number of genes involved spermatogenesis process or spermiogenesis (in the case of round spermatids), show more chromosomal volume in the middle-internal area of the nucleus. Finally, we have observed that sex chromosomes present a dynamic radial positioning during spermatogenesis, directly related to the transcriptional inactivation processes that they experience throughout the process. In relation to the relative positioning between chromosomes, the results showed that the interactions between chromosomes in the nucleus of germ cells and spermatozoa are not random, suggesting relevant functional implications. Even so, it has not been identified any factors that determine the relative position to the exception of the effect chromosome size at pachytene stage and round spermatids. Finally, it has also been concluded that the chromosome positioning in relation to the longitudinal axis of the sperm nucleus is not random, suggesting the importance of an ordered longitudinal positioning for the processes of release and activation of the paternal genome after fertilization.
Jabs, Normund. "Expressionsanalyse des Transkriptionsfaktors Nkx6.1 in Mus musculus (Linneaus, 1758)". [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=975901818.
Pełny tekst źródłaMasterson, Dawn E. "Infanticide and parental care in mice Mus musculus domesticus". Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241418.
Pełny tekst źródłaSmith, Frances Victoria. "Behaviour and immune function in laboratory mice : (Mus musculus)". Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338530.
Pełny tekst źródłaChristophe-Ligonnière, Nathalie. "Echanges possibles entre les deux sous-especes de souris, mus musculus musculus et mus musculus domesticus et leurs hybrides : etude du role des comportements sociaux et des preferences sexuelles". Paris 13, 1999. http://www.theses.fr/1999PA132023.
Pełny tekst źródłaPorcherie, Adeline. "Susceptibilité aux parasites des hybrides entre "Mus musculus" et "Mus musculus domesticus" : origine du phénomène et rôle dans la contre-sélection des hybrides". Montpellier 2, 2005. http://www.theses.fr/2005MON20083.
Pełny tekst źródłaKasper-Sonnenberg, Monika. "Identifizierung und Charakterisierung von Interaktionen synaptischer Proteine aus Mus musculus". [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=983013926.
Pełny tekst źródłaKaltwasser, Sebastian. "Volumetric Manganese Enhanced Magnetic Resonance Imaging in mice (mus musculus)". Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-141742.
Pełny tekst źródłaOliva, Jean L. (Jean Louise). "The Teratogenic Effects of Nocodazole and Acrylamide in Mus Musculus". Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc500254/.
Pełny tekst źródłaBrown, Kara Mutso Amelia Tuttle Alexander H. "Sex dependent affiliation behavior and empathic approach in Mus musculus". Diss., Connect to the thesis, 2008. http://hdl.handle.net/10066/1430.
Pełny tekst źródłaHarper, Antonia C. "Behavioural and physiological effects of neonatal handling of Mus musculus". Thesis, Keele University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401046.
Pełny tekst źródłaWang, Kenan. "Behavioural and neurohumoral mechanisms of environmental analgesia in Mus musculus". Thesis, University of Bradford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305727.
Pełny tekst źródłaRömer, Dirk. "Untersuchungen zur künstlichen Beatmung bei der Maus (Mus musculus) mit dem UNO Micro-Ventilator®". Diss., lmu, 2003. http://nbn-resolving.de/urn:nbn:de:bvb:19-17777.
Pełny tekst źródłaSkinner, N. C. "Aspects of circadian rhythms in feral house mice, Mus musculus L". Thesis, University of Westminster, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373438.
Pełny tekst źródłaRankin, Judith. "Some effects of prenatal exposure to aluminium in mice (Mus musculus)". Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/14251.
Pełny tekst źródłaGONÇALVES, Daniel José Dias. "Efeito da minociclina em Mus Musculus infectados com Trypanosoma brucei brucei". Master's thesis, Instituto de Higiene e Medicina Tropical, 2011. http://hdl.handle.net/10362/11418.
Pełny tekst źródłaThe pathologies of humans and other mammals caused by the haemoflagelate parasite Trypanosoma brucei are a true burden in Africa, killing thousands of people and cattle every year. In the case of human therapeutics, every drug was implemented in the mid-twentieth century, with no new patents being registered since 1981. It is urgent, therefore, to discover new molecules which in a monotherapeutical scheme or in associ-ation with other drugs can somehow intervene in the control of the parasite or the in-flammation caused by successive waves of parasitaemia. In previous studies, minocycline, which is a second generation tetracycline, has proven effective in the protection of the central nervous system (CNS) of infected mice, impeding the passage of the blood-brain barrier (BBB) for both leukocytes and para-sites. In the present study, the effect of this drug seems to correlate with a greater re-sistance to the loss of several haematological components like erythrocytes, leukocytes or granulocytes in samples from animals with 20 days of progression of T. brucei infec-tion. Also, the parasitaemias seem to be substantially lower (10 fold) in treated animals for the same time of infection and for the cytokine pattern, interleukine 4 (IL-4), inter-feron gamma (IFN-γ) and nitric oxid (NO), for which there seems to be a different se-cretion pattern when comparing treated and untreated animals. IL-4, which has a dubi-ous role in the infection by trypanosomes, seems to be related with an anti-inflammatory profile, and NO, essential to control the parasite, exists in greater quanti-ties in treated animals, unlike IFN-γ which displays higher levels in control animals. The latter is described in the literature as a parasite growth factor. The proteinase expression is greater in the spleen, however there are no obvious differences between the two groups, while there is a persistence of a system of two pro-teinases with molecular masses comprised between 30 and 40 kDa in almost all of the samples, which can be endogenous. Yet, there is a strong possibility that this metallo-proteinases can be secreted also by parasites, helping their tissue invasion.
Smithson, Jacqueline Louise. "The effects of corticosterone on persistence of attention in Mus Musculus". Thesis, Keele University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.716859.
Pełny tekst źródłaAmaral, Marta Gonçalves. "Transferência gênica em células espermáticas de Mus musculus e Ramdia quelen". Universidade Federal de Pelotas, 2009. http://guaiaca.ufpel.edu.br/handle/123456789/1270.
Pełny tekst źródłaTransgenic animals have been used as biological models in studies of the genes functions and their mechanisms of action, as well as to improve animal production. Researchers are trying to produce transgenic animals that will be organs donors in xenotransplants. Another use of the transgenic animal is in the production of recombinant proteins for pharmaceutical interest, starting from several tissues and corporal fluids of different animal species. Using TMGT (Testis Mediated Gene Transfer), the efficiency of pEGFP transgene transmission in mice using non surgical TMGT was evaluated, without epididymis electroporation; using transfectants as DMSO, liposomes, and for the first time the DMA. To evaluate the efficiency of non surgical TMGT in F0 the EGFP expression was evaluated in vivo and detection in genome was conducted by PCR analysis. Moreover, we evaluated which transfectants were more efficient in transgene transmission and if it induce histological damage in testis, by histological analysis. EGFP expression was not detected in F0 through the ultraviolet light.The result of the PCR analysis shows that liposomes and DMSO were the best transfectants for pEGFP in F0. The histological analysis shows that injections of DMSO with exogenous DNA could affect the development of the germ cell of seminal tubules. The purpose about SMGT was to evaluate the interaction of the spermatozoa of silver catfish with pEGFP vector. It was observed that the semen after three washes in isosmotic solution and at 1000 x g centrifugation could eliminate seminal plasma proteins and preserve cellular motility. The time of action of DNase in the seminal plasma was 30 minutes, the temperature of action of DNase ranged between 33-53°C and its inhibition was detected at 70°C. In the presence of EDTA 30mM the activity of DNase was inhibited. Through PCR it was detected that in the DNA of the silver catfish s spermatozoids, the amplicon of EGFP at different concentrations of pEGFP vector (5-100 ng/106 spermatozoa). We demonstrate that spermatozoa of the silver catfish need to be washed to remove seminal plasma before contact with exogenous DNA, after several washes exogenous DNA was internalized in spermatozoa.
Os animais transgênicos vêm sendo empregados como modelos biológicos em estudos das funções dos genes e dos seus mecanismos de ação, bem como para melhorar a produção animal. Pesquisadores vêm tentando produzir animais transgênicos que serão doadores de órgãos em xenotransplantes. Outra utilização da transgênese animal é a produção de proteínas recombinantes de interesse farmacêutico a partir de diversos tecidos e fluidos corporais de diferentes espécies de animais. Em relação à TMGT (Testis Mediated Gene Transfer) foi avaliada a eficiência da transmissão do transgene EGFP em camundongos, utilizando a TMGT não cirúrgica, sem o uso de eletroporação no epidídimo; utilizando transfectantes como o DMSO, lipossomos, e pela primeira vez o DMA. A detecção da expressão do EGFP foi avaliada in vivo na F0 e por PCR, para comprovar a eficiência da TMGT não cirúrgica. Também foi analisado qual dos transfectantes propiciou a maior taxa de transmissão e se eles causaram danos histológicos aos testículos, através de análise histológica. Não foi detectada a expressão de EGFP, através da luz ultravioeta na F0. Os resultados da análise de PCR demonstraram que o lipossomo e o DMSO foram os melhores transfectantes do pEGFP na F0. A análise histológica demonstrou que a injeção de DMSO com o DNA exógeno, pode comprometer o desenvolvimento das células germinativas do túbulo seminal. O objetivo em relação à SMGT (Sperm-mediated gene transfer) foi avaliar a interação dos espermatozóides de silver catfish (Rhandia quelen) com o vetor pEGFP. Foi observado que o sêmen após três lavagens em solução isosmótica e centrifugadas à 1000 x g, eliminaram as proteínas do plasma seminal e preservaram a motilidade celular. O tempo de atividade da DNase no plasma seminal foi de 30 minutos, a temperatura de atividade da DNase variou entre 33-53°C e sua inativação ocorreu aos 70°C. Na presença de EDTA 30mM a atividade da DNase foi inibida. Através da PCR foi detectada a presença do pEGFP no DNA dos espermatozoides do silver catfish, que incorporaram o vetor em diferentes concentrações (5-100 ng/106 espermatozoides). Concluímos que os espermatozoides do silver catfish precisam ser lavados para retirada do da DNase do plasma seminal antes de entrar em contato com o DNA exógeno, e que após as lavagens ocorreu a internalização do DNA exógeno no espermatozoide.
Nettles, Rachel Marie. "Bacterial Community Ecology of the Colon in Mus musculus". BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/6912.
Pełny tekst źródłaVanlerberghe, Flavie. "Histoire évolutive de la zone d'hybridation naturelle entre les deux sous-espèces de souris européennes Mus musculus domesticus et Mus musculus musculus : dynamique de l'introgression de gènes autosomaux, de l'ADN mitochondrial et du chromosome Y". Montpellier 2, 1988. http://www.theses.fr/1988MON20001.
Pełny tekst źródłaVanlerberghe, Flavie. "Histoire évolutive de la zone d'hybridation naturelle entre les deux sous-espèces de souris européennes Mus musculus domesticus et Mus musculus musculus dynamique de l'introgression de gènes autosomaux, de l'ADN mitochondrial et du chromosome Y /". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37618998j.
Pełny tekst źródłaMonteros, Juan Carlos. "Conservação evolutiva da proteína STI1 nas espécies Mus musculus e Danio rerio". reponame:Repositório Institucional da UFPR, 2009. http://hdl.handle.net/1884/20677.
Pełny tekst źródłaBerting, Jennifer Irene. "Inbreeding effects on physiological responses to chronic hypoxia in mice (Mus musculus) /". Electronic version (PDF), 2007. http://dl.uncw.edu/etd/2007-3/bertingj/jenniferberting.pdf.
Pełny tekst źródłaCromie, Anthea Alexandra. "Behavioural and physiological counter-strategies to infanticide in mice (Mus musculus domesticus)". Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241423.
Pełny tekst źródłaCostello, Aron K. "Female Characteristics that Influence Male Mate Preference in House Mice (Mus Musculus)". Miami University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=miami1280754434.
Pełny tekst źródłaCottignoli, Stefano <1979>. "Expression and cellular localization of Copper transporter 2 (Ctr2) in Mus musculus". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2009. http://amsdottorato.unibo.it/1883/1/Cottignoli_Stefano_tesi.pdf.
Pełny tekst źródłaCottignoli, Stefano <1979>. "Expression and cellular localization of Copper transporter 2 (Ctr2) in Mus musculus". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2009. http://amsdottorato.unibo.it/1883/.
Pełny tekst źródłaBrockschnieder, Damian. "Herstellung und Charakterisierung eines binär-genetischen Systems zur Zellablation in der Maus (Mus musculus) mittels Diphtherie-Toxin". [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969477996.
Pełny tekst źródłaResühr, David. "Der Einfluss von kalorischer Restriktion und Melatonin auf die circadiane Physiologie der Maus (Mus Musculus, Linnaeus 1758)". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973278099.
Pełny tekst źródłaNeussert, Rudgar [Verfasser]. "Pathomechanismen der Best'schen Makuladystrophie in der Maus (Mus musculus Linnaeus 1758, Muroidea): Funktion des Bestrophins / Rudgar Neussert". München : Verlag Dr. Hut, 2010. http://d-nb.info/1009095285/34.
Pełny tekst źródłaBeiersdorfer, Antonia Benita Verfasser], i Christian [Akademischer Betreuer] [Lohr. "Charakterisierung panglialer Kommunikationsmechanismen im Bulbus olfactorius der Maus (Mus musculus L.) / Antonia Benita Beiersdorfer ; Betreuer: Christian Lohr". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:18-103491.
Pełny tekst źródłaBeiersdorfer, Antonia Benita [Verfasser], i Christian [Akademischer Betreuer] Lohr. "Charakterisierung panglialer Kommunikationsmechanismen im Bulbus olfactorius der Maus (Mus musculus L.) / Antonia Benita Beiersdorfer ; Betreuer: Christian Lohr". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://d-nb.info/1208003038/34.
Pełny tekst źródłaRoberts, David G. "The behavioural endocrinology of infanticide and parental care in mice (Mus musculus domesticus)". Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241500.
Pełny tekst źródłaBarnett, L. K. "The genetic heterogeneity of hair proteins from inbred strains of mouse, Mus musculus". Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355498.
Pełny tekst źródłaChabokdast, Anna. "Multibody dynamics modelling of the masticatory system of the house mouse (Mus musculus)". Thesis, University of Hull, 2015. http://hydra.hull.ac.uk/resources/hull:10929.
Pełny tekst źródłaBelkhir, Khalid. "Différenciation chromosomique et évolution chez "Mus musculus domesticus" : cas des souris robertsoniennes d'Alsace". Montpellier 2, 1991. http://www.theses.fr/1991MON20161.
Pełny tekst źródłaSeth, Pawan. "STUDY OF THE RELATIONSHIP BETWEEN Mus musculus PROTEIN SEQUENCES AND THEIR BIOLOGICAL FUNCTIONS". University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1176736255.
Pełny tekst źródłaForestier, Tatiana. "Environnement socio-olfactif et choix alimentaires chez la souris domestique, Mus musculus domesticus". Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCD003/document.
Pełny tekst źródłaThe ecological success of the house mouse, Mus musculus domesticus, implies a great capacity to adapt its diet to available food resources. The social transmission of food preference (STFP) is an adaptive type of learning observed in rodents allowing them to enlarge their food repertoire at lower risk by getting olfactory information on novel food sources from conspecifics. This social learning takes place directly, during an encounter with a conspecific or indirectly, via olfactory marks. The objective of this thesis work was to determine how mice use their socio-olfactory environment to make food choices. Our results revealed that the absence of the conspecific during the indirect STFP reduces the social constraints associated with an encounter and allows the acquisition of STFP between unfamiliar conspecifics. However, some physical constraints associated with the perception of information in feces may reduce the availability of food information. We also showed that different sex concerns of individuals may affect the prioritization of information present in feces and limit, in males, the acquisition of STFP. Our results suggest that the use of food information in mice varies according to their social and ecological context and involves different processes such as emotion and attention. Under natural conditions, the direct and indirect STFP could be complementary, each of them extending the conditions for the transmission of food information in rodents