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1

Ericsson, Emma M., Lars Faxälv, Anna Weissenrieder, Agneta Askendal, Tomas L. Lindahl i Pentti Tengvall. "Glycerol monooleate–blood interactions". Colloids and Surfaces B: Biointerfaces 68, nr 1 (styczeń 2009): 20–26. http://dx.doi.org/10.1016/j.colsurfb.2008.09.016.

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Pitzalis, Paolo, Maura Monduzzi, Niels Krog, Helena Larsson, Helena Ljusberg-Wahren i Tommy Nylander. "Characterization of the Liquid−Crystalline Phases in the Glycerol Monooleate/Diglycerol Monooleate/Water System". Langmuir 16, nr 15 (lipiec 2000): 6358–65. http://dx.doi.org/10.1021/la0002031.

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Eychenne, Valérie, Laurent Debrauwer i Zéphirin Mouloungui. "O-etherification between glycerol and glycerol monooleate—demonstration of formation of diglycerol monooleate and triglycerol monooleate by fast atom bombardment-mass spectroscopy and 13C nuclear magnetic resonance". Journal of Surfactants and Detergents 3, nr 2 (kwiecień 2000): 173–77. http://dx.doi.org/10.1007/s11743-000-0122-3.

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4

Song, Na, Ai-juan Wang, Jun-ming Li, Zhuo Zhu, Huijun Shi, Xiao-long Ma i Dejun Sun. "Study on influencing factors of Pickering emulsions stabilized by hydroxyapatite nanoparticles with nonionic surfactants". Soft Matter 14, nr 19 (2018): 3889–901. http://dx.doi.org/10.1039/c8sm00241j.

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Salentinig, S., Mahsa Zabara, P. Parisse i H. Amenitsch. "Formation of highly ordered liquid crystalline coatings – an in situ GISAXS study". Physical Chemistry Chemical Physics 20, nr 34 (2018): 21903–9. http://dx.doi.org/10.1039/c8cp03205j.

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6

Kumar, Manoj, i Guruswamy Kumaraswamy. "Phase behaviour of the ternary system: monoolein–water–branched polyethylenimine". Soft Matter 11, nr 28 (2015): 5705–11. http://dx.doi.org/10.1039/c5sm01082a.

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7

Adilina, Indri Badria, Egi Agustian, Yenny Meliana i Anny Sulaswatty. "SYNTHESIS AND PROPERTIES OF ETHOXYLATED GLYCEROL MONOOLEATE AS PALM OIL BASED NONIONIC SURFACTANTS". Jurnal Kimia Terapan Indonesia 17, nr 1 (10.06.2015): 49–55. http://dx.doi.org/10.14203/jkti.v17i1.22.

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Palm oil based nonionic surfactants were synthesized by reacting glycerol monooleate with ethylene oxide at 80 ºC in the prescence of an alkaline catalyst. Purification of the products was conducted by use of acetic acid and black carbon which gave ethoxylated products (EGMO) with a higher level of viscocity and greater solubility in water. Physical and chemical properties of the product such as surface activity, cloud point, acid value, ester value, hydroxyl value, and hydrophilic-lipophilic balance was also determined and results varied depending on the reagent molar ratio. The synthesized EGMO were soluble in water and therefore show potential use as surface active agents in personal care and cosmetic products.Keywords: nonionic surfactant, ethoxylation, glycerol monooleate, palm oil
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8

Piriyaprasarth, Suchada, Pornsak Sriamornsak, Gaysorn Chansiri, W. Promboot, U. Imerb i D. Sumpoung. "Effect of Coconut Oil and Surfactants on Stability of Nanoemulsions". Advanced Materials Research 506 (kwiecień 2012): 429–32. http://dx.doi.org/10.4028/www.scientific.net/amr.506.429.

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The objective of this study was to investigate the effect of coconut oil and different surfactants on stability of nanoemulsions that were prepared by simple homogenization (13,500 rpm, 10 minutes). Coconut oil, sunflower oil and castor oil at the concentration of 20-40% w/w were used as the oil phase. Polysorbate 20, polysorbate 80 and Cremophore RH40 were used as surfactant whereas sorbitan monooleate and polyethylene glycol 400 were used as co-surfactants. The formulations containing coconut oil in the range of 20-40% w/w and the ratio of polysorbate 80 to sorbitan monooleate of 2:1 and 3:1 provided nanosized emulsions (100-500 nm). The zeta potential values ranged from-41.51 to-16.97 mV. The prepared nanoemulsions were stable for at least 7 days at 8 °C. The temperature cycling test (storage at 4 °C for 24 hours and at 45 °C for 24 hours) was performed. It was found that the formulation containing 30% w/w of coconut oil, 22.5% w/w of polysorbate 80 and 7.5% w/w of sorbitan monooleate was stable for 1 cycle. The results indicated that a decrease in the concentration of surfactant and an increase in the concentration of oil affected the stability of nanoemulsions.
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9

Innocenti Malini, R., M. Zabara, M. Gontsarik, K. Maniura-Weber, R. M. Rossi, F. Spano i S. Salentinig. "Self-assembly of glycerol monooleate with the antimicrobial peptide LL-37: a molecular dynamics study". RSC Advances 10, nr 14 (2020): 8291–302. http://dx.doi.org/10.1039/c9ra10037g.

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10

Han, Sanghwa. "Molecular Dynamics Simulation of Sorbitan Monooleate Bilayers". Bulletin of the Korean Chemical Society 34, nr 3 (20.03.2013): 946–48. http://dx.doi.org/10.5012/bkcs.2013.34.3.946.

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11

Bora, Plaban, Lakhya Jyoti Konwar i Dhanapati Deka. "Microemulsion based hybrid biofuels using glycerol monooleate". Energy Conversion and Management 117 (czerwiec 2016): 185–92. http://dx.doi.org/10.1016/j.enconman.2016.03.026.

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12

Conejero, Claudia, Leire Loidi i Marcos Hervella. "Contact dermatitis caused by polyethylene glycol-7 monooleate". Contact Dermatitis 72, nr 3 (21.01.2015): 185–86. http://dx.doi.org/10.1111/cod.12340.

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13

Zhou, Zukang, i Benjamin Chu. "Viscosity of semidilute solutions of cobalt monooleate soap". Journal of Colloid and Interface Science 133, nr 2 (grudzień 1989): 348–57. http://dx.doi.org/10.1016/s0021-9797(89)80043-8.

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14

Jia, Puyou, Caiying Bo, Lihong Hu i Yonghong Zhou. "Synthesis and characterization of glyceryl monooleate-based polyester". Korean Journal of Chemical Engineering 32, nr 3 (4.12.2014): 547–51. http://dx.doi.org/10.1007/s11814-014-0214-0.

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15

Koroleva, M. Yu, D. A. Kovalenko, V. M. Shkinev, O. N. Katasonova, B. Ya Spivakov i E. V. Yurtov. "Synthesis of copper nanoparticles stabilized by polyoxyethylenesorbitan monooleate". Russian Journal of Inorganic Chemistry 56, nr 1 (styczeń 2011): 6–10. http://dx.doi.org/10.1134/s0036023611010141.

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16

Arina, Herlin, i Mohammad Nasikin. "Enhancement of Flow Properties Biodiesel Using Sorbitan Monooleate". Scientific Contributions Oil and Gas 45, nr 3 (1.12.2022): 143–52. http://dx.doi.org/10.29017/scog.45.3.1262.

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Depletion of fossil fuel and increased pollution caused by the burning of fossil fuel is a leading factor in to use of alternate energy especially palm oil biodiesel as a mixture of diesel oil fuel (B-XX). It was reported that the use of the B-20 caused a blockage in the vehicle’s fuel filter. The blockage is caused by the presence of deposits formed from the agglomeration of monoglycerides. Three different biodiesels with monoglyceride content were used 0.40% - 0.60% by mass. The addition of monoglyceride standards (monopalmitin, monostearin, and monoolein) to biodiesel increases the volume of monoglyceride precipitates formed. The presence of these deposits decreases the flow properties of B-20. Research has been carried out to improve the flow properties of biodiesel by adding Sorbitan Monooleate (CMOST) surfactant, especially cloud points (CP) and cold filter plugging point (CFPP) parameters. The addition of 0.10%w - 1%w CMOST can reduce the CP by 4.80oC and CFPP by 2oC. This proves that the addition of SMO will improve the flow properties of B-XX as an alternative energy.
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17

Meng, Linghui, Guoliang Shen, Shengnan Zhang, Chao Zhou, Yaojie Han i Ruiyang Wen. "New Technology for the Synthesis of Glycerol Monooleate". Journal of Oleo Science 72, nr 5 (2023): 549–56. http://dx.doi.org/10.5650/jos.ess22180.

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18

Mkhize, J. N., i A. P. Gupta. "The importance of formulating insect growth regulators with surfactants and their blends for the control of the rice weevil, Sitophilus oryzae (L.) (Coleoptera: Curculionidae)". Insect Science and Its Application 6, nr 2 (kwiecień 1985): 183–86. http://dx.doi.org/10.1017/s1742758400006603.

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AbstractThe use of surfactants and their blends to improve the penetration of two insect growth regulators (IGRs; hydroprene and R-20458) into wheat kernels was investigated. It was found that formulation of IGRs with a surfactant, Tween-85 (polyoxyethylene trioleate), increased mortality and/or effectiveness of the IGRs. Formulation of hydroprene with a blend of Span-80 (sorbitan monooleate) with Tween-80 (polyoxyethylene monooleate) produced results comparable to those by hydroprene with Tween-85. However, formulations of IGRs with surfactants with high or low hydrophile-lipophile balance (HLB), failed to provide suitable control of the weevil, probably due to the type of emulsions formed. The same results were obtained with hydroprene formulations with blends of Spans and Tweens, even though their HLBs were close to that of Tween-85. Residual half-life for hydroprene was about three months; formulations with Tween-85 or a blend of Span-80 did not enhance the residual activity for hydroprene in wheat.
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19

Kaewbanjong, Jarika, Thanaporn Amnuaikit i Prapaporn Boonme. "Formulation and Characterization of Clotrimazole Microemulsions and Microemulsion-Based Gels". International Journal of Nanoscience 13, nr 04 (sierpień 2014): 1440005. http://dx.doi.org/10.1142/s0219581x14400055.

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This study aimed to formulate and physically characterized clotrimazole microemulsions and microemulsion based-gels compared with their blank counterparts. Microemulsions were prepared by simple mixing of isopropyl palmitate, 2:1 mixture of water and isopropyl alcohol and 1:1 mixture of polyethylene 20 sorbitan monooleate and sorbitan monooleate. To develop microemulsion-based gels, fumed silica was use as a thickening agent at 2.5, 5 or 7.5% w/w. All studied formulations, i.e., 2 microemulsions and 6 microemulsion based-gels were investigated for physical properties such as appearance, conductivity, pH, rheological behavior and spreadability. Afterwards, 2 microemulsions (ME1 and ME2) and 2 microemulsion based-gels (MBG1-3 and MBG2-2) were selected to incorporate with clotrimazole and then investigated for physical properties. All formulations showed good appearance and physical properties. Clotrimazole did not affect most characteristics of their blank counterparts, except conductivity. Therefore, the investigated microemulsions and microemulsion based gels could be used as the vehicles of clotrimazole for skin drug delivery.
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20

Miao, Chun Yan, Gang Lü, Ke Cao, You Wei Yao, Guo Yi Tang i Duan Weng. "Preparation of Silica Microcapsules Containing Phase Change Paraffin Wax". Materials Science Forum 561-565 (październik 2007): 631–34. http://dx.doi.org/10.4028/www.scientific.net/msf.561-565.631.

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This paper deals with the preparation of silica microcapsules containing phase change paraffin wax for thermal energy storage and the determination of their thermal properties. The spherical microcapsule samples respectively containing two types of paraffin wax (with peak melting temperature of 29.3 °C (type P1) and 35.5 °C (type P2), and the fusion heat of 140 J/g (type P1) and 153 J/g (type P2)) as core and chemically and thermally stable silica as shell, were prepared from O/W emulsion systems in the presence of polyvinyl alcohol as stabilizer, and sorbitan monooleate and poilyoxyethylene(20) sorbitan monooleate as emulsifiers. The silica shell formed via hydrolysis and condensation from tetraethyl silicate with acetate acid as catalyst. The fusion heat of the two samples is 101 J/g and 112 J/g respectively. Property of adaptable temperature of the as-made microcapsules is measured through a self-made cell model. The maximum difference between the temperature of the cell with PCM wallpaper and that of the cell with controlled wallpaper is about 1.1 °C.
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21

Hu, Donghao, Kazuyoshi Ogawa, Mikio Kajiyama i Toshiharu Enomae. "Characterization of self-assembled silver nanoparticle ink based on nanoemulsion method". Royal Society Open Science 7, nr 5 (maj 2020): 200296. http://dx.doi.org/10.1098/rsos.200296.

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A well-dispersed self-assembled silver nanoparticles (AgNPs) ink with high purity was synthesized via AgNO 3 emulsion prepared by blending an AgNO 3 aqueous solution and a liquid paraffin solution of both polyoxyethylene (20) sorbitan monooleate (Tween 80) and sorbitan monooleate (Span 80). The ink remained as an emulsion at low temperatures; however, it produced AgNPs after sintering at about 60°C and showed a high stability at nanoscale sizes (with diameters ranging 8.6–13.4 nm) and a high conductivity. During the whole procedure, Tween 80 acted as a surfactant, reductant and stabilizer. Presumably, Tween 80 underwent an autoxidation process, where a free radical of an α-carbon of ether oxygen was formed by hydrogen abstraction. The mean diameter of emulsion droplets could be reduced by decreasing water content and increasing the ratio of surfactant and concentration of AgNO 3 aqueous solution. Consequently, the thermogravimetric analysis and X-ray diffraction result clarified the purity of the produced Ag 0 . Dynamic light scattering and ultraviolet-visible spectroscopy clarified that an increased concentration of AgNO 3 decreased the particle size.
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Pakpayat, Natthida, i Prapaporn Boonme. "Effects of Various Co-Surfactants and Oils on Microemulsion Formation in Decylglucoside System". Advanced Materials Research 747 (sierpień 2013): 653–56. http://dx.doi.org/10.4028/www.scientific.net/amr.747.653.

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Decylglucoside is a non-ionic, non-toxic, biodegradable surfactant. This work aimed to establish composition where stable microemulsions could form using hydrophilic lipophilic deviation (HLD) concept to optimise the formulations. Scanning for suitable ratios of surfactant and co-surfactant was carried out by altering the surfactant/co-surfactant (S/CoS) ratios with two co-surfactants and seven different oils in order to find the optimum formulations. From the optimal S/CoS ratios, pseudo-ternary phase diagrams by dilution were subsequently performed, leading to obtain microemulsion zones. The zones of microemulsions could be observed in the systems composed of decylglucoside/sorbitan monooleate/isopropyl myristate/water at the 0.10/0.90 and 0.20/0.80 S/CoS ratios and decylglucoside/sorbitan monooleate /isopropyl palmitate/water at the 0.10/0.90, 0.15/0.85 and 0.20/0.80 S/CoS ratios. The microemulsion zones of two systems were similar and found at high surfactant concentrations. However, the studied decylglucoside microemulsion systems were interesting in drug and cosmetic applications because it consisted of non-ionic surfactant and co-surfactant, resulting low toxic products.
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23

Zhen, Guoliang, Tracey M. Hinton, Benjamin W. Muir, Shuning Shi, Mark Tizard, Keith M. McLean, Patrick G. Hartley i Pathiraja Gunatillake. "Glycerol Monooleate-Based Nanocarriers for siRNA Delivery in Vitro". Molecular Pharmaceutics 9, nr 9 (10.08.2012): 2450–57. http://dx.doi.org/10.1021/mp200662f.

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Thorat, Kiran R., i Ravindra B. Laware. "Formulation and evaluation of Lornoxicam loaded Lyotropic liquid crystalline gel". Journal of Drug Delivery and Therapeutics 9, nr 6 (15.11.2019): 116–25. http://dx.doi.org/10.22270/jddt.v9i6.3702.

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GIT irritation is prominent limitation with the use of Non-steroidal anti-inflammatory drugs (NSAID’s). There is rising interest in designing formulations which will deliver the drug at the site of action as topical gels, to avoid GIT irritation and other systemic side effects. Liquid Crystal phase has emerged as a novel material for the preparation of topical drug delivery system. In present study the attempt is made to prepare Lornoxicam loaded lyotropic liquid crystalline gel using glycerol monooleate. Glycerol monooleate is biocompatible, bioadhesive, penetration enhancer and sustain release agent. It also promotes ceramide extraction and enhancement of lipid fluidity in the stratum corneum region of the skin. Five formulation of lornoxicam were prepared and evaluated for parameters like drug content, viscosity, spreadability, Extrudability In-vitro drug release along with in vivo study. In-Vitro and Ex-Vivo drug release kinetics showed that there was 72.85% and 77.98% drug release within 48 hrs. Skin irritation test suggested that prepared formulation was safe for human use. In-Vivo evaluation of this formulation was done by carrageenan induced rat paw edema anti-inflammatory model. Keywords: Lornoxicam, GMO, Lyotropic liquid crystal, Anti-Inflammatory, Topical drug delivery
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Wu, Pey-Shiuan, Chia-Hui Lin, Yi-Ching Kuo i Chih-Chien Lin. "Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method". Advances in Materials Science and Engineering 2021 (14.12.2021): 1–9. http://dx.doi.org/10.1155/2021/8580992.

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Octyl methoxycinnamate and butyl methoxydibenzoylmethane are organic UV filters with poor photostability and will become photoallergy or phototoxic substance when exposed to ultraviolet radiation. The organic UV filters coated by microcapsules can reduce the photodegradation and avoid direct contact with the skin. Through microencapsulation, the application of UV filters in cosmetics becomes more effective and safer. This study first used the sol-gel method to create organic/inorganic composite UV filter microcapsules. We used sodium alginate as a shell material of the microcapsule to encapsulate UV filters. CaCO3 and tetraethyl orthosilicate (TEOS) were used as cross-linking agents, and sorbitan monooleate (Span 80) and polyoxyethylenesorbitan monooleate (Tween 80) were used as emulsifiers in the interfacial polymerization method for preparation. The results indicated that the microcapsules with 3 g of CaCO3 cross-linking agents had a similar particle size and better entrapment efficiency. The average sizes were 61.0 ± 4.9 μm and 48.6 ± 4.7 μm, and entrapment efficiencies were 75.3 ± 1.9% and 74.8 ± 1.7% for octyl methoxycinnamate and butyl methoxydibenzoylmethane, respectively. Utilizing sodium alginate as a cross-linking agent is better than TEOS due to the higher calcium content. In vitro transdermal delivery analysis showed that the release rate became steady.
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Elsayed, Amani, Amany Belal i Khaldoun Al-Sou’od. "Preparation and optimization of glyceryl monooleate-low molecular weight chitosan nanoparticles for delivery of morpholinopyrrolizine derivative". Tropical Journal of Pharmaceutical Research 21, nr 9 (12.10.2022): 1813–21. http://dx.doi.org/10.4314/tjpr.v21i9.1.

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Purpose: To develop and optimize glyceryl monooleate–low-molecular-weight chitosan (GMO-LMWC) nanoparticles loaded with morpholinopyrrolizine derivative (NPM). Methods: Molecular mechanics was used to determine the main driving force for the complexation between glyceryl monooleate (GMO) and chitosan. Nanoparticles were fabricated using a modified film-rehydration method. Optimization was carried out using a statistical design approach. The effects of formulation factors (concentrations of GMO, LMWC and Tween 80) on zeta potential and particle size were investigated using a 23 factorial design. Results: A steady increase in binding energy was observed when chitosan length was increased from 22 to 142 Å, and thereafter it remained almost constant. The examined independent variables had significant effects on particle size and zeta potential. The particle size of the nanoparticles varied from 265 to 1270 nm while zeta potential was in the range of 3 – 12 mV. The optimized preparation showed a significantly low half-maximal inhibitory concentration (IC50) when compared to a free anticancer agent in the hepatocellular carcinoma (HePG-2) cell line. Conclusion: A nanoparticulate system composed of GMO and LMWC is a potential nanocarrier for delivery of morpholinopyrrolizine derivative.
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Ahmad, Javed, Showkat R. Mir, Kanchan Kohli, Krishna Chuttani, Anil K. Mishra, A. K. Panda i Saima Amin. "Solid-Nanoemulsion Preconcentrate for Oral Delivery of Paclitaxel: Formulation Design, Biodistribution, andγScintigraphy Imaging". BioMed Research International 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/984756.

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Aim of present study was to develop a solid nanoemulsion preconcentrate of paclitaxel (PAC) using oil [propylene glycol monocaprylate/glycerol monooleate, 4 : 1 w/w], surfactant [polyoxyethylene 20 sorbitan monooleate/polyoxyl 15 hydroxystearate, 1 : 1 w/w], and cosurfactant [diethylene glycol monoethyl ether/polyethylene glycol 300, 1 : 1 w/w] to form stable nanocarrier. The prepared formulation was characterized for droplet size, polydispersity index, and zeta potential. Transmission electron microscopy (TEM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) were used to assess surface morphology and drug encapsulation and its integrity. Cumulative drug release of prepared formulation through dialysis bag and permeability coefficient through everted gut sac were found to be remarkably higher than the pure drug suspension and commercial intravenous product (Intaxel), respectively. Solid nanoemulsion preconcentrate of PAC exhibited strong inhibitory effect on proliferation of MCF-7 cells in MTT assay.In vivosystemic exposure of prepared formulation through oral administration was comparable to that of Intaxel inγscintigraphy imaging. Our findings suggest that the prepared solid nanoemulsion preconcentrate can be used as an effective oral solid dosage form to improve dissolution and bioavailability of PAC.
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Ковальчук, Ксения Михайловна, Виолетта Андреевна Веролайнен i Светлана Анатольевна Темникова. "INVESTIGATION OF THE EFFECT OF SURFACTANTS OF VARIOUS NATURE ON THE RESUSPENDABILITY AND SEDIMENTATION STABILITY OF MENTHOL SUSPENSION". Вестник Тверского государственного университета. Серия: Химия, nr 2(44) (25.06.2021): 131–37. http://dx.doi.org/10.26456/vtchem2021.2.13.

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Исследовано влияние поверхностно-активных веществ (ПАВ) различной природы: твина-80, сорбитана моноолеата SPAN-80, додецилсульфата натрия, и синтанола промышленного производства ДС-10 на ресуспендируемость и седиментационную устойчивость водной суспензии ментола. The effect of surfactants of various natures (tween-80, sorbitan monooleate SPAN-80, sodium dodecyl sulfate, and industrial-grade synthanol DS-10) on the resuspendability and sedimentation stability of an aqueous menthol suspension was studied.
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Yamashita, Masatsugu, Hideya Adachi, Takeshi Nakamura, Hajime Taniguchi, Satoru Onogi i Makoto Hisamatsu. "Characteristics of Amylose Forming Complexes with Glycerol Monooleate and Monostearate." Journal of Applied Glycoscience 50, nr 1 (2003): 37–39. http://dx.doi.org/10.5458/jag.50.37.

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Navarro‐Triviño, Francisco J., i Ricardo Ruiz‐Villaverde. "Photoallergic systemic dermatitis caused by sorbitan monooleate in craft beer". Contact Dermatitis 83, nr 3 (5.05.2020): 230–32. http://dx.doi.org/10.1111/cod.13562.

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Zi-yang, Ding, Gu Gui-zhou, Hu Xiu-bo, Li Dan i Song Xin-yang. "Optimum Synthesis Conditions of High Quality Explosive Emulsifier Sorbitol Monooleate". IOP Conference Series: Earth and Environmental Science 267 (8.06.2019): 062047. http://dx.doi.org/10.1088/1755-1315/267/6/062047.

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Kale, Smita S., i Krishnacharya G. Akamanchi. "Trehalose Monooleate: A Potential Antiaggregation Agent for Stabilization of Proteins". Molecular Pharmaceutics 13, nr 12 (18.11.2016): 4082–93. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00686.

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Zhou, Zukang, Yannis Georgalis, Wenping Liang, Jialin Li, Renliang Xu i Benjamin Chu. "Colloidal behavior of cobalt monooleate soap in apolar organic solvents". Journal of Colloid and Interface Science 116, nr 2 (kwiecień 1987): 473–84. http://dx.doi.org/10.1016/0021-9797(87)90143-3.

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Kato, Keiichi, Peter Walde, Norio Koine, Sosaku Ichikawa, Takashi Ishikawa, Ryo Nagahama, Takehiko Ishihara i in. "Temperature-Sensitive Nonionic Vesicles Prepared from Span 80 (Sorbitan Monooleate)". Langmuir 24, nr 19 (7.10.2008): 10762–70. http://dx.doi.org/10.1021/la801581f.

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Milak, Spomenka, Angela Chemelli, Otto Glatter i Andreas Zimmer. "Vancomycin Loaded Glycerol Monooleate Liquid Crystalline Phases Modified with Surfactants". Pharmaceutics 12, nr 6 (8.06.2020): 521. http://dx.doi.org/10.3390/pharmaceutics12060521.

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The influence of two tuning agents, polyglycerol ester (PE) and triblock copolymer (TC), on the properties of glycerol monooleate (MO) liquid crystalline phase (LCP) was investigated to achieve the therapeutic concentration of vancomycin hydrochloride (VHCl) into the eye, topically during 60 min (1 h) and intravitreally during 2880 min (48 h). Different techniques were used to elucidate the impact of surfactants on the structure of the LCP: polarized light microscopy (PLM), small-angle X-ray scattering (SAXS), and in vitro release tests I and II (simulating local and intravitreal application in the eye). The structure analysis by SAXS depicts that the inclusion of PE into the MO LCP provided partial transition of a hexagonal phase into a lamellar phase, and TC induced a partial transition of a hexagonal phase into an LCP which identification was difficult. The LCP modulated with PE and TC demonstrated different VHCl’s release patterns and were evaluated by comparing our release data with the literature data. The comparison indicated that the LCP modulated with 30% w/w PE could be a promising VHCl delivery system intravitreally during 2880 min.
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36

Gagliardi, Agnese, Donato Cosco, Betty P. Udongo, Luciana Dini, Giuseppe Viglietto i Donatella Paolino. "Design and Characterization of Glyceryl Monooleate-Nanostructures Containing Doxorubicin Hydrochloride". Pharmaceutics 12, nr 11 (24.10.2020): 1017. http://dx.doi.org/10.3390/pharmaceutics12111017.

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Glyceryl monooleate (GMO) is one of the most popular amphiphilic lipids, which, in the presence of different amounts of water and a proper amount of stabilizer, can promote the development of well defined, thermodynamically stable nanostructures, called lyotropic liquid crystal dispersions. The aim of this study is based on the design, characterization, and evaluation of the cytotoxicity of lyotropic liquid crystal nanostructures containing a model anticancer drug such as doxorubicin hydrochloride. The drug is efficiently retained by the GMO nanosystems by a remote loading approach. The nanostructures prepared with different non-ionic surfactants (poloxamers and polysorbates) are characterized by different physico-chemical features as a function of several parameters, i.e., serum stability, temperature, and different pH values, as well as the amount of cryoprotectants used to obtain suitable freeze-dried systems. The nanostructures prepared with poloxamer 407 used as a stabilizer show an increased toxicity of the entrapped drug on breast cancer cell lines (MCF-7 and MDA-MB-231) due to their ability to sensitize multidrug-resistant (MDR) tumor cells through the inhibition of specific drug efflux transporters. Moreover, the interaction between the nanostructures and the cells occurs after just a few hours, evidencing a huge cellular uptake of the nanosystems.
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37

Lee, Jaehwi, i Ian W. Kellaway. "Peptide Washout and Permeability from Glyceryl Monooleate Buccal Delivery Systems". Drug Development and Industrial Pharmacy 28, nr 9 (styczeń 2002): 1155–62. http://dx.doi.org/10.1081/ddc-120014582.

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38

Jain, Vikas, Nitin K. Swarnakar, Prabhat R. Mishra, Ashwni Verma, Ankur Kaul, Anil K. Mishra i Narendra K. Jain. "Paclitaxel loaded PEGylated gleceryl monooleate based nanoparticulate carriers in chemotherapy". Biomaterials 33, nr 29 (październik 2012): 7206–20. http://dx.doi.org/10.1016/j.biomaterials.2012.06.056.

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39

Bradley-Shaw, Joshua L., Philip J. Camp, Peter J. Dowding i Ken Lewtas. "Molecular Dynamics Simulations of Glycerol Monooleate Confined between Mica Surfaces". Langmuir 32, nr 31 (27.07.2016): 7707–18. http://dx.doi.org/10.1021/acs.langmuir.6b00091.

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40

Milak, Spomenka, i Andreas Zimmer. "Glycerol monooleate liquid crystalline phases used in drug delivery systems". International Journal of Pharmaceutics 478, nr 2 (styczeń 2015): 569–87. http://dx.doi.org/10.1016/j.ijpharm.2014.11.072.

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41

Cuomo, Francesca, Giuseppe Cinelli, Catalina Chirascu, Emanuele Marconi i Francesco Lopez. "Antioxidant Effect of Vitamins in Olive Oil Emulsion". Colloids and Interfaces 4, nr 2 (29.05.2020): 23. http://dx.doi.org/10.3390/colloids4020023.

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In this study, water-in-extra virgin olive oil emulsions were enriched with vitamins. Water-in oil emulsions are heterogeneous systems able to solubilize both hydrophilic and hydrophobic compounds. Thus, hydrophilic vitamin C and lipophilic vitamin E were loaded separately or together in emulsion. A suitable emulsion composition was selected after considering different surfactant (mono and diglycerides of fatty acids, E471; sorbitan monooleate, Span 80; polyoxyethylene sorbitan monooleate, Tween 80) and water concentrations. The most appropriate emulsion, for the high stability, resulted the one containing concentrations of Span 80 1% w/w and water 1% w/w. The antioxidant effect of vitamins in emulsions was studied considering the variation of the peroxide values during storage. The oxidation reaction was slowed down in emulsions containing vitamin C, but it was quickened by the loading of vitamin E for its high concentration. In emulsions containing vitamin E, indeed, the peroxide values were higher than in emulsions prepared in the absence of vitamins or in oil. The antioxidant activity generated by the co-loading of vitamin C and E was very effective to the point that in presence of high amounts of vitamins the peroxide values did not change in about 40 days of storage, due to the vitamin E regeneration by vitamin C.
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42

Dabkowska, Aleksandra P., Maria Valldeperas, Christopher Hirst, Costanza Montis, Gunnar K. Pálsson, Meina Wang, Sofi Nöjd i in. "Non-lamellar lipid assembly at interfaces: controlling layer structure by responsive nanogel particles". Interface Focus 7, nr 4 (16.06.2017): 20160150. http://dx.doi.org/10.1098/rsfs.2016.0150.

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Biological membranes do not only occur as planar bilayer structures, but depending on the lipid composition, can also curve into intriguing three-dimensional structures. In order to fully understand the biological implications as well as to reveal the full potential for applications, e.g. for drug delivery and other biomedical devices, of such structures, well-defined model systems are required. Here, we discuss the formation of lipid non-lamellar liquid crystalline (LC) surface layers spin-coated from the constituting lipids followed by hydration of the lipid layer. We demonstrate that hybrid lipid polymer films can be formed with different properties compared with the neat lipid LC layers. The nanostructure and morphologies of the lipid films formed reflect those in the bulk. Most notably, mixed lipid layers, which are composed of glycerol monooleate and diglycerol monooleate with poly( N -isopropylacrylamide) nanogels, can form films of reverse cubic phases that are capable of responding to temperature stimulus. Owing to the presence of the nanogel particles, changing the temperature not only regulates the hydration of the cubic phase lipid films, but also the lateral organization of the lipid domains within the lipid self-assembled film. This opens up the possibility for new nanostructured materials based on lipid–polymer responsive layers.
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43

Cho, Kyung-Jin, Won-Kyung Cho, Jeon-Pyung Lee, Min-Soo Kim, Jeong-Soo Kim i Sung-Joo Hwang. "Evaluation of Glyceryl Monooleate(GMO) W/O Emulsion Stability by using Turbiscan®LAB". Journal of Korean Pharmaceutical Sciences 39, nr 4 (20.08.2009): 249–55. http://dx.doi.org/10.4333/kps.2009.39.4.249.

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Jeon, Mi-Sun, Cho-Rong Lee i Ki-Teak Lee. "Production of Diacylglycerol-Oil from Lipase-Catalyzed Reaction Using Soybean Oil and Glyceryl Monooleate". Journal of the Korean Society of Food Science and Nutrition 38, nr 11 (30.11.2009): 1559–63. http://dx.doi.org/10.3746/jkfn.2009.38.11.1559.

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45

Wang, Weiwei, Zhuangzhuang Liu, Qimin Song, Xindi Zhang, Shengkai Jiao, Yao Xu, Quanda Xu i Dezun Sheng. "Tribological performance of organic molybdenum in the presence of organic friction modifier". PLOS ONE 16, nr 6 (10.06.2021): e0252203. http://dx.doi.org/10.1371/journal.pone.0252203.

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The tribological performance of organic molybdenum in the present of organic friction modifier was investigated in this study. Three types of organic friction modifiers were selected, which are Glycerol monooleate, Pentaerythritol and N,N-Dimethylhexadecylamine. The organic molybdenum are MoDTC, MoDDP and molybdenum amide. Friction coefficient and wear were studied in block-on-ring test rig with steel test specimens. Experimental results indicate the Pentaerythritol shows synergistic effect with MoDTC in wide range temperature, while increased the friction coefficient of molybdenum amide in high temperature. N,N-Dimethylhexadecylamine shows synergistic effect with molybdenum amide, while hindered the friction reduction performance of MoDTC in low temperature. The presence of Glycerol monooleate reduced friction coefficient of MoDTC in low temperature, while increased the friction coefficient of molybdenum amide in most situations. All the tested organic friction modifiers improved the friction reduction performance of MoDDP. Most of the tested organic friction modifiers reduced the wear of organic molybdenum. The PT shows the best anti-wear performance with MoDTC. The tribo-chemical products in test specimens lubricated with different lubricant formulas indicate that the presences of Pentaerythritol promotes the production of MoS2 in MoDTC. N,N-Dimethylhexadecylamine promotes the production of MoS2 in molybdenum amide. The side products of MoO1.6S1.6 and Cr/MoS2 of MoDDP in high temperature lead to high friction coefficient.
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46

Dhal, Somali, Abdullah Alhamidi, Saeed M. Al-Zahrani, Arfat Anis i Kunal Pal. "The Influence of Emulsifiers on the Physiochemical Behavior of Soy Wax/Rice Bran Oil-Based Oleogels and Their Application in Nutraceutical Delivery". Gels 9, nr 1 (6.01.2023): 47. http://dx.doi.org/10.3390/gels9010047.

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This research evaluated the influence of stearic acid, sunflower lecithin, and sorbitan monooleate on soy wax (SYW)/rice bran oil (RBO)-based oleogels. The physiochemical behavior of oleogel samples was evaluated using colorimetry, microscopy, FTIR, mechanical, crystallization kinetics, X-ray diffraction, and a drug release investigation. The prepared oleogels were light yellow, and adding emulsifiers did not change their appearance. All oleogels showed an oil binding capacity of >98%, independent of emulsifier treatment. The surface topography revealed that emulsifiers smoothed the surface of the oleogels. Bright-field and polarized micrographs showed the presence of wax grains and needles. FTIR spectra indicated that oleogel samples had the same functional group diversity as the raw materials. The oleogel samples lacked a hydrogen-bonding peak. Hence, we postulated that non-covalent interactions were involved in the oleogel preparation. According to stress relaxation studies, the firmness and elastic component of oleogels were unaffected by emulsifiers. However, EML3 (oleogel containing sorbitan monooleate) showed lower relaxing characteristics than the others. EML3 exhibited the slowest crystallization profile. Due to its low d-spacing, EML3 was found to have densely packed crystal molecules and the largest crystallite size. The in vitro drug release studies showed that emulsifier-containing oleogels dramatically affected curcumin release. These results may help customize oleogels properties to adjust bioactive component release in the food and pharmaceutical industries.
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47

Sotirova, Yoana, Viliana Gugleva, Stanila Stoeva, Iliyan Kolev, Rositsa Nikolova, Maria Marudova, Krastena Nikolova, Yoana Kiselova-Kaneva, Minka Hristova i Velichka Andonova. "Bigel Formulations of Nanoencapsulated St. John’s Wort Extract—An Approach for Enhanced Wound Healing". Gels 9, nr 5 (25.04.2023): 360. http://dx.doi.org/10.3390/gels9050360.

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This study aimed to develop a semisolid vehicle for topical delivery of nanoencapsulated St. John’s wort (SJW) extract, rich in hyperforin (HP), and explore its wound-healing potential. Four nanostructured lipid carriers (NLCs) were obtained: blank and HP-rich SJW extract-loaded (HP-NLC). They comprised glyceryl behenate (GB) as a solid lipid, almond oil (AO), or borage oil (BO) representing the liquid lipid, along with polyoxyethylene (20) sorbitan monooleate (PSMO) and sorbitan monooleate (SMO) as surfactants. The dispersions demonstrated anisometric nanoscale particles with acceptable size distribution and disrupted crystalline structure, providing entrapment capacity higher than 70%. The carrier exhibiting preferable characteristics (HP-NLC2) was gelled with Poloxamer 407 (PM407) to serve as the hydrophilic phase of a bigel, to which the combination of BO and sorbitan monostearate (SMS) organogel was added. The eight prepared bigels with different proportions (blank and nanodispersion-loaded) were characterized rheologically and texturally to investigate the impact of the hydrogel-to-oleogel ratio. The therapeutic potential of the superior formulation (HP-NLC-BG2) was evaluated in vivo on Wistar male rats through the tensile strength test on a primary-closed incised wound. Compared with a commercial herbal semisolid and a control group, the highest tear resistance (7.764 ± 0.13 N) was achieved by HP-NLC-BG2, proving its outstanding wound-healing effect.
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Belaya, N. I., A. V. Belyi i A. F. Lutsyuk. "Dissociation constants of phenol in the presence of polyoxyethylene sorbitan monooleate". Russian Journal of Applied Chemistry 86, nr 4 (kwiecień 2013): 520–24. http://dx.doi.org/10.1134/s1070427213040113.

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Sánchez, Nieves, Mercedes Martínez i José Aracil. "Selective Esterification of Glycerine to 1-Glycerol Monooleate. 1. Kinetic Modeling". Industrial & Engineering Chemistry Research 36, nr 5 (maj 1997): 1524–28. http://dx.doi.org/10.1021/ie9603124.

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Sánchez, Nieves, Mercedes Martínez i José Aracil. "Selective Esterification of Glycerine to 1-Glycerol Monooleate. 2. Optimization Studies". Industrial & Engineering Chemistry Research 36, nr 5 (maj 1997): 1529–34. http://dx.doi.org/10.1021/ie960313w.

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