Artykuły w czasopismach na temat „Migraine”
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Cuciureanu, Dan Iulian, Cătălina Elena Bistriceanu, Georgiana-Anca Vulpoi, Tudor Cuciureanu, Florina Antochi i Adina-Maria Roceanu. "Migraine Comorbidities". Life 14, nr 1 (2.01.2024): 74. http://dx.doi.org/10.3390/life14010074.
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Novel knowledge about the interrelationships and reciprocal effects of migraine and epilepsy, migraine and mood disorders, or migraine and irritable bowel syndrome has emerged in recent decades. Over time, comorbid pathologies associated with migraine that share common physiopathological mechanisms were studied. Among these studied pathologies is epilepsy, a disorder with common ion channel dysfunctions as well as dysfunctions in glutamatergic transmission. A high degree of neuronal excitement and ion channel abnormalities are associated with epilepsy and migraine and antiepileptic drugs are useful in treating both disorders. The coexistence of epilepsy and migraine may occur independently in the same individual or the two may be causally connected. The relationship between cortical spreading depression (CSD) and epileptic foci has been suggested by basic and clinical neuroscience research. The most relevant psychiatric comorbidities associated with migraine are anxiety and mood disorders, which influence its clinical course, treatment response, and clinical outcome. The association between migraine and major depressive disorder can be explained by a robust molecular genetic background. In addition to its role as a potent vasodilator, CGRP is also involved in the transmission of nociception, a phenomenon inevitably linked with the stress and anxiety caused by frequent migraine attacks. Another aspect is the role of gut microbiome in migraine’s pathology and the gut–brain axis involvement. Irritable bowel syndrome patients are more likely to suffer migraines, according to other studies. There is no precise explanation for how the gut microbiota contributes to neurological disorders in general and migraines in particular. This study aims to show that migraines and comorbid conditions, such as epilepsy, microbiota, or mood disorders, can be connected from the bench to the bedside. It is likely that these comorbid migraine conditions with common pathophysiological mechanisms will have a significant impact on best treatment choices and may provide clues for future treatment options.
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Yamanaka, Gaku, Soken Go, Shinichiro Morichi, Mika Takeshita, Natsumi Morishita, Shinji Suzuki, Takamatsu Tomoko i in. "Clinical Features and Burden Scores in Japanese Pediatric Migraines With Brainstem Aura, Hemiplegic Migraine, and Retinal Migraine". Journal of Child Neurology 35, nr 10 (1.06.2020): 667–73. http://dx.doi.org/10.1177/0883073820927840.
Pełny tekst źródłaStreszczenie:
Background: Migraines are a broad spectrum of disorders classified by the type of aura with some requiring attentive treatment. Vasoconstrictors, including triptans, should be avoided in the acute phase of migraines with brainstem aura, in hemiplegic migraine, and in retinal migraine. This study investigated the characteristics and burden of these migraines. Methods: Medical charts of 278 Japanese pediatric patients with migraines were retrospectively reviewed. Migraine burden of migraines with brainstem aura, hemiplegic migraines, and retinal migraine was assessed using the Headache Impact Test-6™ (HIT-6) and the Pediatric Migraine Disability Assessment scale (PedMIDAS). Results: Of 278 patients screened, 12 (4.3%) patients with migraines with brainstem aura (n = 5), hemiplegic migraines (n = 2), and retinal migraine (n = 5) were enrolled in the study. All patients had migraine with/without typical aura, whereas some patients had coexisting migraine with another type of headache (chronic tension-type headache in 3 patients, and 1 each with frequent episodic tension-type headache, headache owing to medication overuse, and chronic migraine). Migraines with brainstem aura, hemiplegic migraines, and retinal migraine patients with coexisting headaches had higher HIT-6 or PedMIDAS scores, whereas migraines with brainstem aura, hemiplegic migraines, and retinal migraine patients without coexisting headache did not show high HIT-6 or PedMIDAS scores. Conclusion: All migraines with brainstem aura, hemiplegic migraines, and retinal migraine patients experienced migraine with or without typical aura, and some patients having other coexisting headaches also had high PedMIDAS and HIT-6 scores. PedMIDAS and HIT-6 should not be considered diagnostic indicators of migraines with brainstem aura, hemiplegic migraines, or retinal migraine. In clinical practice for headaches in children, careful history taking and proactive assessment of the aura are needed for accurate diagnosis of migraines with brainstem aura, hemiplegic migraines, and retinal migraine.
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Simic, Svetlana, Petar Slankamenac, Milan Cvijanovic, Sofija Banic-Horvat, Zita Jovin i Miroslav Ilin. "Menstrual migraine". Medical review 60, nr 9-10 (2007): 449–52. http://dx.doi.org/10.2298/mpns0710449s.
Pełny tekst źródłaStreszczenie:
Introduction. The prevalence of migraine in childhood and adolescence has not changed to a great extent, but it increases in adolescence, especially in female adolescents. Menstrual migraine ? definition. There are two types of menstrual migraine: true menstrual migraine and menstrual related migraine. True menstrual migraine occurs predominantly around menstruation, whereas menstrual related migraine occurs during menstruation, but also at other times during the month. Causes. Exaggerated or abnormal neurotransmitter responses to normal cyclic changes in the ovarian hormones are probably the basic cause of menstrual migraines. The fall in estrogen levels during menstrual cycle is trigger for the menstrual migraine. Symptoms. Menstrual migraine has the same symptoms as other types of migraine, but the pain is stronger, IT lasts longer, AND IT IS more frequent than other types of migraines. Diagnosis. In order to make a diagnosis, women are asked to keep a headache diary for three months. If the migraine headache is severe and occurs regularly between two days before and three days after the start of menstrual bleeding, it is true menstrual migraine. Therapy. Menstrual migraines are more difficult to treat than other types of migraines. Treatment principles for menstrual migraine are the same as for migraines in general, with certain particularities. Conclusion. Hormonally associated migraine is a specific clinical entity. It is important to diagnose the type of migraine, considering the fact that a decline in estrogen level at the end of menstrual cycle triggers migraine, so it can be treated by low levels of estrogen. .
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Susanti, Restu, i Syamel Muhammad. "Menstrual Migraine : How Hormones Impact Migraine". Journal Obgin Emas 5, nr 1 (18.01.2021): 9–17. http://dx.doi.org/10.25077/aoj.5.1.9-17.2021.
Pełny tekst źródłaStreszczenie:
Menstrual Migraine is divided into 2 subtypes: Menstrually Related Migraine (MRM) and Pure Menstrual Migraines (PMM). In PMM symptoms do not occur outside the menstrual cycle while MRM, symptoms can occur at other times apart from the menstrual cycle. The occurrence of menstrual migraines is related to the female hormones cycle in the form of the decrease in estrogen levels which usually occurs a week before the onset of menstruation. The mechanism is unclear, but it is thought that a decrease in estrogen levels can trigger decrease in serotonin levels, causing cranial vasodilation and sensitization of the trigeminal nerve. Keywords: menstrual migraine, hormones
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Sun, Juan. "Migraines in medical students from Inner Mongolia University". Pacific International Journal 5, nr 3 (1.10.2022): 65–77. http://dx.doi.org/10.55014/pij.v5i3.201.
Pełny tekst źródłaStreszczenie:
Aims: This study aimed to evaluate the prevalence of migraines and related factors.
Methods: The survey employed was a self-administered questionnaire regarding various migraine symptoms and related factors administered to medical students attending Inner Mongolia Medical College in China. We calculate migraine prevalence and evaluate migraine-related factors. Migraine prevalence based on related factors and according to gender were compared using χ2 tests. The proportion of other symptoms related to migraines was also calculated.
Results: 17.2% of surveyed students had experienced migraines. The migraines prevalence among students who used the computer for over three hours was nearly 1.5 times higher than for those who used it for less than one hour. Of those students who used a computer for more than 3 hours, migraine prevalence among female students was approximately 1.5 times greater than for males. The migraine prevalence among students with poor sleep was nearly two times higher than among those with good sleep. The migraine prevalence among students with anxiety was approximately 2.5 times higher relative to those who experienced no anxiety. The most common symptom complaint associated with migraines (>97%) included limited ability to study and restricted daily activities.
Conclusions: Although the migraine prevalence in our study was moderate, it led to serious limitations in students’ study time and daily activities. In addition to measures to relieve anxiety and improve sleep quality, stricter control of computer use will be necessary, especially in female. Taken together, our study provides better insight regarding medical students’ migraine-related problems.
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Kumaat, Matthew A., Junita M. Pertiwi i Arthur H. P. Mawuntu. "Hubungan antara Migrain dan Kafein". e-CliniC 9, nr 2 (16.03.2021): 334. http://dx.doi.org/10.35790/ecl.v9i2.32864.
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Abstract: Migraine is one of the primary headaches that often causes moderate to severe disability. One of the most commonly consumed psychoactive substances associated with migraine is caffeine. This study was aimed to evaluate the relationship between migraine and caffeine thoroughly based on various studies. This was a literature review study using databases of Pubmed/Medline, Cochrane, Wiley Online Library, Science Direct, Google Scholar, and Garuda. The eligibility criteria for this study were observational research articles or clinical trials, written in Indonesian or English, published in the last five years, and their fulltexts could be accessed. The results obtained 10 articles. Almost all of them showed that caffeine could cause migraine whether after caffeine consumption (non-absent group) or no consumption of caffeine (absent group). The association of caffeine with migraine was more significant than with tension headaches. Besides being a trigger factor of migraine, caffeine cpuld also act as a migraine therapy. In conclusion, there is a close association between migraine and caffeine. Migraine tends to be triggered than to be reduced by caffeine.Keywords: caffeine, migraine Abstrak: Migrain merupakan salah satu jenis nyeri kepala primer yang sering menyebabkan disabilitas sedang dan berat. Salah satu zat psikoaktif yang umum dikonsumsi dan berhubungan dengan migrain yaitu kafein. Penelitian ini bertujuan untuk menelaah hubungan migrain dan kafein lebih mendalam berdasarkan berbagai penelitian. Jenis penelitian ialah literature review menggunakan database dari Pubmed/Medline, Cochrane, Wiley Online Library, Science Direct, Google Scholar, dan Garuda. Kriteria kelayakan artikel penelitian ialah artikel penelitian observasional atau uji klinis, ditulis dalam Bahasa Indonesia atau Inggris, terbit dalam lima tahun terakhir, dan naskah lengkap artikel dapat diakses secara lengkap. Hasil penelitian mendapatkan 10 artikel penelitian. Hampir semua penelitian memperlihatkan bahwa kafein dapat menyebabkan migrain baik setelah kafein dikonsumsi (kelompok nonabsen) maupun saat kafein sudah tidak dikonsumsi (kelompok absen). Hubungan kafein dengan migrain lebih kuat dibandingkan dengan nyeri kepala tipe tegang. Selain menjadi factor pencetus, kafein juga dapat berperan sebagai terapi migrain. Simpulan penelitian ini ialah terdapat hubungan erat antara migrain dan kafein. Migrain cenderung lebih sering dicetuskan oleh kafein dibandingkan diringankan oleh kafein.Kata kunci: kafein, migrain
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Reuter, U., MS Del Rio, H.-C. Diener, G. Allais, B. Davies, A. Gendolla, J. Pfeil, S. Schwalen, B. Schäuble i J. van Oene. "Migraines with and without aura and their response to preventive therapy with topiramate". Cephalalgia 30, nr 5 (1.10.2009): 543–51. http://dx.doi.org/10.1111/j.1468-2982.2009.01999.x.
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Data from the Prolonged Migraine Prevention (PROMPT) with Topiramate trial were evaluated post hoc to determine whether topiramate could prevent migraine auras, and whether its efficacy in preventing migraine headaches was similar in patients with (MA; n = 269) and without (MoA; n = 542) aura. Migraines and auras were recorded during prospective baseline, 6-month open-label (OL) topiramate and 6-month double-blind (DB), placebo-controlled phases. In the last 28 OL days, migraines without aura and migraine auras decreased by 43.1% and 54.1%, respectively, in MA patients. MoA patients experienced a 44.3% reduction in migraines. In the DB phase, increases in migraines with placebo vs. topiramate were similar to the full study, but were generally not statistically significant, probably due to lack of power in the subgroup analysis. Similarly, there were no statistically significant changes in number of auras between groups. Thus, topiramate appears to reduce migraine auras in parallel with headache reductions, which are similar in patients with and without aura.
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Fu, Xianguo, Jing Yang, Xiaoyang Wu, Qifang Lin, Yuli Zeng, Qiaoqing Xia, Luoyuan Cao, Baoying Huang i Genbin Huang. "Association between PRDM16, MEF2D, TRPM8, LRP1 gene polymorphisms and migraine susceptibility in the She ethnic population in China". Clinical and Investigative Medicine 42, nr 1 (23.03.2019): E21—E30. http://dx.doi.org/10.25011/cim.v42i1.32389.
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Background: The prevalence of migraines in the She population, a minority in China, is significantly higher than that in Han Chinese and other Asian populations. Two single nucleotide polymorphisms (SNPs) have been found to be associated with migraine susceptibility in the She population.
Purpose: This study investigated four SNPs, identified in genome-wide association studies, within migraine-susceptible loci in Han Chinese for their association with migraine susceptibility in the She population.
Methods: Two-hundred unrelated migraine patients and 200 healthy controls
were recruited. The SNPs examined included rs2651899 (PRDM16 ), rs2274316 (MEF2D ), rs7577262 (TRPM8) and rs11172113 (LRP1). Genotyping of the SNPs was performed by allele-specific polymerase chain reaction and direct sequencing.
Results: No significant differences between the participants with migraines and controls (participants without migraines) were demonstrated in genotypes, alleles and allele carriage frequencies for the four SNPs. A subgroup analysis found that migraine with aura had a lower frequency of C allele positivity in rs2651899 than in healthy controls (59.6% vs. 74.5%, respectively; P < 0.034). Univariate analyses indicated that no genotype of the four SNPs had a significant association with migraines. Males had a lower risk of migraines, and advanced age was a significant risk factor for migraines in females.
Conclusion: The SNPs in four migraine susceptible loci in Han Chinese were not risk factors for migraines in a relatively small sample of the She population.
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Cooke, Lara J., i Werner J. Becker. "Migraine Prevalence, Treatment and Impact: The Canadian Women and Migraine Study". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 37, nr 5 (wrzesień 2010): 580–87. http://dx.doi.org/10.1017/s0317167100010738.
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Background:The prevalence of migraine headache varies somewhat across geographic regions. The last Canadian population-based study of migraine was in 1994. We report the findings of the Canadian Women and Migraine Survey. In addition to reporting migraine prevalence in Canadian women, the survey identified current consultation and treatment practices of women with migraine, and the psychological burden of migraine.Methods:The survey was conducted with a population-based sample of 1210 women using standard telephone research methods. Headache diagnoses were based on the International Headache Society (IHS) Classification.Results:Calculated prevalence of migraine headache was 26%. Only 51% of women with migraine had consulted a physician about their headaches. Women with migraines rely on over-the-counter medications and non-specific prescription medications. Less than 10% of women with migraine use triptans/dihydroergotamine for primary treatment. Ninety seven percent of women with migraine reported at least one psychosocial impact resulting from migraines.Conclusions:The prevalence of migraine in Canadian women appears static, and is again shown to be slightly higher than that reported in the United States. As in other epidemiologic studies, many women with migraine do not seek medical help for their headaches and perhaps as a result, few are using migraine-specific medications to treat their headaches. The impact of migraine on Canadian women is substantial with almost all women with migraine reporting adverse psychosocial effects of migraines on their lives.
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Rościszewska-Żukowska, Iwona, Sabina Galiniak i Halina Bartosik-Psujek. "Clinical Characteristics of Headache in Multiple Sclerosis Patients: A Cross-Sectional Study". Journal of Clinical Medicine 12, nr 10 (17.05.2023): 3518. http://dx.doi.org/10.3390/jcm12103518.
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Primary headaches are known to be associated with multiple sclerosis (MS), but previous studies concerning this relationship are not conclusive. Nowadays, there are no studies assessing the prevalence of headaches in Polish MS patients. The aim of the study was to assess the prevalence and characterise headaches in MS patients treated with disease-modifying therapies (DMTs). In a cross-sectional study of 419 consecutive RRMS patients, primary headaches were diagnosed according to the International Classification of Headache Disorders (ICHD-3) criteria. Primary headaches were observed in 236 (56%) of RRMS patients, with a higher prevalence in women (ratio of 2:1). The most common was migraine 174 (41%) (migraine with aura 80 (45%), migraine without aura 53 (30%), and probable migraine without aura 41 (23%); less frequent was tension-type headache 62 (14%). Female sex was a risk factor for migraines but not for tension-type headaches (p = 0.002). Migraines mostly started before MS onset (p = 0.023). Migraine with aura was associated with older age, longer disease duration (p = 0.028), and lower SDMT (p = 0.002). Longer DMT time was associated with migraine (p = 0.047), particularly migraine with aura (p = 0.035). Typical for migraine with aura were headaches during clinical isolated syndrome (CIS) (p = 0.001) and relapses (p = 0.025). Age and type of CIS, oligoclonal band presence, family MS history, EDSS, 9HTP, T25FW, and type of DMT did not correlate with headache. Headaches are present in more than half of MS patients treated with DMTs; migraines occur almost three times more frequently than tension-type headaches. Migraines with aura headaches during CIS and relapses are typical. Migraine in MS patients had high severity and typical migraine characteristics. DMTs had no correlation with the presence or type of headache.
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Allais, Gianni, Margarita Sanchez del Rio, Hans-Christoph Diener, Chiara Benedetto, Joop Pfeil, Barbara Schäuble i Joop van Oene. "Perimenstrual migraines and their response to preventive therapy with topiramate". Cephalalgia 31, nr 2 (22.07.2010): 152–60. http://dx.doi.org/10.1177/0333102410378049.
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Introduction: Preventive treatment with topiramate is effective for overall reduction of migraine frequency, but there are few data regarding its efficacy on perimenstrual migraines. To determine whether topiramate can prevent perimenstrual migraines, we analyzed data from premenopausal women as a subgroup of the Prolonged Migraine Prevention with Topiramate (PROMPT) study. Methods: In total, 198 women from the PROMPT study with menstrually related migraine (MRM) were evaluated. After a one-to-two–month prospective baseline period, patients received open-label topiramate (50–200 mg/day) for six months. Results: During topiramate treatment, mean monthly migraine frequency was reduced from 7.03 at baseline to 4.36 (mean change: −2.66; p < .001, endpoint analysis). Mean percentage reductions were similar for migraines during and outside the perimenstrual period (−45.9% and −46.1%, respectively). In patients with aura, reductions in migraine days with (−48.3%) or without (−43.4%) aura were similar to those in patients without aura (−45.4%). Reductions were also similar whether women were taking combined oral contraceptives (−47.0%) or were not (−46.6%). Conclusions: Topiramate reduces the frequency, but not severity or duration, of perimenstrual migraines in women with MRM, including migraines with and without aura, and regardless of combined oral contraceptive use.
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Beiraghi Toosi, Mehran, Alireza Ghodsi, Mehrdad Sarabi, Sara Ghahremani, Nasrin Fazeli i Somayeh Ghahremani. "Investigating the Frequency of Infantile Colic in Children with Migraine". Journal of Child Science 11, nr 01 (styczeń 2021): e89-e92. http://dx.doi.org/10.1055/s-0041-1728729.
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AbstractInfantile colic is a common problem observed within the first 3 months of life in infants and is a common cause of crying among infants. Migraine is a common cause of recurrent primary headaches during childhood. The pathogenesis of migraine and colic has remained unknown, but various factors seem to be involved. Patients with migraine may have a medical history of infantile colic, and infantile colic is considered an early manifestation of migraine. In this study, we investigate the frequency of history of infantile colic in 6- to 14-year-old children with migraines. In this case–control study, 80 children with the diagnosis of migraine and 100 children without migraine, all within the age range of 6 to 14 years, were included. A checklist was completed for each person about the background information and history of infantile colic as well as the history of migraine in parents. Among the children with migraine, 92.5%, and in the control group, 10%, had a familial history of migraine. Also, among the children with migraine, 61.25%, and in the control group, 4%, had a history of infantile colic. The obtained results showed that the frequency of a history of infantile colic was significantly higher in the case group than in the control group. This study provides some evidence regarding the presence of association between infantile colic as well as the familial history of migraines and developing migraines in the future. However, due to some limitations of the retrospective manner of the study, the results should be completed with future studies.
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Wells, Bryan J., Malissa J. Wood, Anne E. O’Duffy, Jennifer A. Sumner, Gerald Chi, Anna Grodzinsky, Heather L. Gornik i in. "Migraine headache in patients with spontaneous coronary artery dissection: A report of the iSCAD Registry". Vascular Medicine 29, nr 3 (czerwiec 2024): 286–95. http://dx.doi.org/10.1177/1358863x241252444.
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Introduction: Spontaneous coronary artery dissection (SCAD) is a nonatherosclerotic cause of myocardial infarction. Migraine headache has been reported to be common among patients with SCAD, but the degree of migraine-related disability has not been quantified. Methods: Clinical data and headache variables were obtained from the baseline assessment of the prospective, multicenter iSCAD Registry. Migraine-related disability was quantified using the self-reported Migraine Disability Assessment (MIDAS). Demographic, clinical, psychosocial, and medical characteristics from data entry forms were compared between patients with and without migraine. Results: Of the 773 patients with available data, 46% reported previous or current migraines. Those with migraines were more likely to be women (96.9% vs 90.3%, p = 0.0003). The presence of underlying carotid fibromuscular dysplasia was associated with migraine (35% vs 27%, p = 0.0175). There was not a significant association with carotid artery dissection and migraine. Current migraine frequency was less than monthly (58%), monthly (24%), weekly (16%), and daily (3%). Triptan use was reported in 32.5% of patients, and 17.5% used daily migraine prophylactic medications. Using the MIDAS to quantify disability related to migraine, 60.2% reported little or no disability, 14.4% mild, 12.7% moderate, and 12.7% severe. The mean MIDAS score was 9.9 (mild to moderate disability). Patients with SCAD had higher rates of depression and anxiety (28.2% vs 17.7% [ p = 0.0004] and 35.3% vs 26.7% [ p = 0.0099], respectively). Conclusions: Migraines are common, frequent, and a source of disability in patients with SCAD. The association between female sex, anxiety, and depression may provide some insight for potential treatment modalities.
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Dai, Lingling, Qiang Xu, Xing Xiong, Yang Yu, Ximing Wang, Hui Dai, Hongru Zhao i Jun Ke. "Propagation Structure of Intrinsic Brain Activity in Migraine without Aura". Brain Sciences 12, nr 7 (10.07.2022): 903. http://dx.doi.org/10.3390/brainsci12070903.
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Previous studies have revealed highly reproducible patterns of temporally lagged brain activity in healthy human adults. However, it is unknown whether temporal organization of intrinsic activity is altered in migraines or if it relates to migraine chronification. In this resting-state functional magnetic resonance imaging study, temporal features of intrinsic activity were investigated using resting-state lag analysis, and 39 episodic migraine patients, 17 chronic migraine patients, and 35 healthy controls were assessed. Temporally earlier intrinsic activity in the hippocampal complex was revealed in the chronic migraine group relative to the other two groups. We also found earlier intrinsic activity in the medial prefrontal cortex in chronic compared with episodic migraines. Both migraine groups showed earlier intrinsic activity in the lateral temporal cortex and sensorimotor cortex compared with the healthy control group. Across all patients, headache frequency negatively correlated with temporal lag of the medial prefrontal cortex and hippocampal complex. Disrupted propagation of intrinsic activity in regions involved in sensory, cognitive and affective processing of pain may contribute to abnormal brain function during migraines. Decreased time latency in the lateral temporal cortex and sensorimotor cortex may be common manifestations in episodic and chronic migraines. The temporal features of the medial prefrontal cortex and hippocampal complex were associated with migraine chronification.
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Setiawati, Octa Reni, Akhmad Kheru Dharmawan, Woro Pramesti i Ani Oktasari. "Hubungan Stres Dengan Kejadian Migrain Pada Mahasiswa Fakultas Kedokteran Universitas Malahayati Di Saat Pandemi Covid-19". MAHESA : Malahayati Health Student Journal 2, nr 2 (13.04.2022): 390–400. http://dx.doi.org/10.33024/mahesa.v2i2.4520.
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ABSTRACT Stress is a general pattern of reactions and adaptations, in the sense that the pattern of reactions to stressors, which can come from within or outside the individual concerned, can be real or not. Headaches called migraines are headaches with pain attacks lasting 4 – 72 hours. Pain is usually unilateral, throbbing, moderate to severe pain intensity and exacerbated by activity, and may be accompanied by nausea and vomiting, photophobia and phonophobia. Complaints that are quite frequent and disturbing from among these complaints are migraine complaints. Migraines can interfere with academic achievement and can limit student activities. To be able to determine the relationship between stress and migraine incidence in students of the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. This type of research uses analytical research methods, namely research conducted to examine the relationship between 2 or more variables as many as 60 samples of students from the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. that meet the inclusion criteria. Data collection began in September 2020. By using a questionnaire as the main measuring tool to collect data. The data were evaluated by Spearman's test. In this study, The research sample was 60 students, indicating that most of the respondents had normal stress levels (50.6%), and showed that most of the respondents had migraine levels (51.9%). The results of the Spearman correlation obtained p value = 0.000 and r = 0.746 because p = 0.000 <0.05. This study, there is a significant correlation between Stress and Migraine Incidence in Students of the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. Keywords: Stress, Migraine, Covid-19 ABSTRAK Stres merupakan pola reaksi serta adaptasi umum, dalam arti pola reaksi menghadapi stresor, yang dapat berasal dari dalam maupun luar individu yang bersangkutan, dapat nyata maupun tidak nyata sifatnya. Nyeri kepala yang disebut migrain adalah nyeri kepala dengan serangan nyeri yang berlangsung 4 – 72 jam. Nyeri biasanya unilateral, sifatnya berdenyut, intensitas nyerinya sedang sampai berat dan diperhebat oleh aktivitas, dan dapat disertai mual muntah, fotofobia dan fonofobia. Keluhan yang cukup sering terjadi dan mengganggu dari antara keluhan tersebut adalah keluhan migrain. Migrain dapat menganggu prestasi akademik dan dapat membatasi kegiatan mahasiswa. Untuk dapat mengetahui Hubungan Stres dengan Kejadian Migrain pada Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. Jenis Penelitian ini menggunakan metode penelitian analitik yaitu penelitian yang dilakukan untuk menguji hubungan 2 variabel atau lebih sebanyak 60 sampel Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. yang memenuhi kriteria inkulsi. Pengambilan data dimulai pada bulan September 2020. Dengan menggunakan kuisioner sebagai alat ukur utama untuk mengumpulkan data. Data dievaluasi dengan uji Spearman. Didapatkan sampel penelitian berjumlah 60 Mahasiswa/i menunjukkan bahwa sebagian besar responden memiliki tingkat stres normal (50,6%), dan menunjukkan bahwa sebagian besar responden memiliki tingkat migrain (51,9%). Hasil korelasi Spearman didapatkan nilai p=0.000 dan nilai r=0.746 karena nilai p=0.000 <0.05. Terdapat korelasi yang bermakna antara Stres dengan Kejadian Migrain pada Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. Kata Kunci: Stress, Migrain, Covid-19
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Setiawati, Octa Reni, Akhmad Kheru Dharmawan, Woro Pramesti i Ani Oktasari. "Hubungan Stres Dengan Kejadian Migrain Pada Mahasiswa Fakultas Kedokteran Universitas Malahayati Di Saat Pandemi Covid-19". MAHESA : Malahayati Health Student Journal 2, nr 2 (13.04.2022): 390–400. http://dx.doi.org/10.33024/mahesa.v2i2.4520.
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ABSTRACT Stress is a general pattern of reactions and adaptations, in the sense that the pattern of reactions to stressors, which can come from within or outside the individual concerned, can be real or not. Headaches called migraines are headaches with pain attacks lasting 4 – 72 hours. Pain is usually unilateral, throbbing, moderate to severe pain intensity and exacerbated by activity, and may be accompanied by nausea and vomiting, photophobia and phonophobia. Complaints that are quite frequent and disturbing from among these complaints are migraine complaints. Migraines can interfere with academic achievement and can limit student activities. To be able to determine the relationship between stress and migraine incidence in students of the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. This type of research uses analytical research methods, namely research conducted to examine the relationship between 2 or more variables as many as 60 samples of students from the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. that meet the inclusion criteria. Data collection began in September 2020. By using a questionnaire as the main measuring tool to collect data. The data were evaluated by Spearman's test. In this study, The research sample was 60 students, indicating that most of the respondents had normal stress levels (50.6%), and showed that most of the respondents had migraine levels (51.9%). The results of the Spearman correlation obtained p value = 0.000 and r = 0.746 because p = 0.000 <0.05. This study, there is a significant correlation between Stress and Migraine Incidence in Students of the Faculty of Medicine, Malahayati University during the Covid-19 pandemic. Keywords: Stress, Migraine, Covid-19 ABSTRAK Stres merupakan pola reaksi serta adaptasi umum, dalam arti pola reaksi menghadapi stresor, yang dapat berasal dari dalam maupun luar individu yang bersangkutan, dapat nyata maupun tidak nyata sifatnya. Nyeri kepala yang disebut migrain adalah nyeri kepala dengan serangan nyeri yang berlangsung 4 – 72 jam. Nyeri biasanya unilateral, sifatnya berdenyut, intensitas nyerinya sedang sampai berat dan diperhebat oleh aktivitas, dan dapat disertai mual muntah, fotofobia dan fonofobia. Keluhan yang cukup sering terjadi dan mengganggu dari antara keluhan tersebut adalah keluhan migrain. Migrain dapat menganggu prestasi akademik dan dapat membatasi kegiatan mahasiswa. Untuk dapat mengetahui Hubungan Stres dengan Kejadian Migrain pada Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. Jenis Penelitian ini menggunakan metode penelitian analitik yaitu penelitian yang dilakukan untuk menguji hubungan 2 variabel atau lebih sebanyak 60 sampel Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. yang memenuhi kriteria inkulsi. Pengambilan data dimulai pada bulan September 2020. Dengan menggunakan kuisioner sebagai alat ukur utama untuk mengumpulkan data. Data dievaluasi dengan uji Spearman. Didapatkan sampel penelitian berjumlah 60 Mahasiswa/i menunjukkan bahwa sebagian besar responden memiliki tingkat stres normal (50,6%), dan menunjukkan bahwa sebagian besar responden memiliki tingkat migrain (51,9%). Hasil korelasi Spearman didapatkan nilai p=0.000 dan nilai r=0.746 karena nilai p=0.000 <0.05. Terdapat korelasi yang bermakna antara Stres dengan Kejadian Migrain pada Mahasiswa/i Fakultas Kedokteran Universitas Malahayati disaat pandemi Covid-19. Kata Kunci: Stress, Migrain, Covid-19
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Lui, Jacob Z., Nathan P. Young, Jon O. Ebbert, Jordan K. Rosedahl i Lindsey M. Philpot. "Loneliness and Migraine Self-Management: A Cross-Sectional Assessment". Journal of Primary Care & Community Health 11 (styczeń 2020): 215013272092487. http://dx.doi.org/10.1177/2150132720924874.
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Background: Chronic illness is often comorbid with the psychological state of loneliness. Models of care for patients who experience chronic migraines may often lack an understanding of psychosocial influences of the illness. Addressing the effects of loneliness on the health behaviors of chronic migraine patients may further elucidate gaps in care that exist beyond the biomedical approach to migraine treatment. The primary aim of this study was to assess the relationship between loneliness and behavioral health decisions in chronic migraine patients, specifically patient ability to self-manage, and effectiveness of treatments. Methods: We conducted a cross-sectional survey among patients (n = 500) with migraine and assessed for the experience of loneliness by using the University of California, Los Angeles–Revised (UCLA-R) Three-item Loneliness Scale and the extent of migraine-related disability via the Migraine Disability Assessment (MIDAS). Furthermore, we evaluated patients for their ability to self-manage their migraines, and perceived effectiveness of treatment. Results: Nearly half of our population reported at least one measure of loneliness (230/500, 46.0%). Patients experiencing chronic migraine were statistically more likely to report feeling lonely when compared to patients with episodic migraines ( P < .001). Patients who report loneliness had lower odds of feeling ’very satisfied” with their ability to self-manage their migraine symptoms (aOR = 0.34, 95% CI 0.14-0.81) and had lower odds of feeling “very satisfied” with their ability to avoid conditions that cause their headache (aOR = 0.39, 95% CI 0.16-0.91). Conclusions: Loneliness has significant effects on the illness experience of patients with chronic migraines, including their ability to self-manage or be satisfied with their current state of care. Psychosocial models of care that address loneliness among patients with chronic migraine may help improve health outcomes and management.
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Saisu, Akihiro, Muneto Tatsumoto, Eisei Hoshiyama, Saiko Aiba i Koichi Hirata. "Evaluation of olfaction in patients with migraine using an odour stick identification test". Cephalalgia 31, nr 9 (31.05.2011): 1023–28. http://dx.doi.org/10.1177/0333102411410612.
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Aims: Peculiar characteristics of migraine headaches include the arousal of olfaction during the attacks and osmophobia. We performed an olfactory test to evaluate the association between olfaction and migraines. Methods: We evaluated olfactory dysfunction in 80 migraine patients (31 experienced migraines with aura (MWA), 49 migraine without aura (MWOA)) and 30 healthy controls. Participants were assessed for concurrent osmophobia. Olfaction was evaluated using an odour stick identification test (OSIT), in which participants were asked to identify various odours during a migraine-free period. The degree of offensiveness of each odour was also evaluated. Results: Sixty-three percent of migraine patients were found to have concurrent osmophobia (MWA 71%; MWOA 57%). The percentages of migraine patients and controls who correctly identified test odours were 91% (92%, MWA; 89%, MWOA) and 92%, respectively. Perfume, rose and Japanese cypress odours were more offensive to migraine patients than to controls. All test odours were found to be more offensive to MWA than to MWOA patients. Conclusions: The OSIT showed certain odours to be highly offensive to migraine patients even when they were not experiencing migraine headaches. More attention should be paid to odours that are perceived to be offensive by migraine patients, particularly those with MWA.
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Rumuat, Jennifer Telly, i Andreas Rantepadang. "Hubungan Stres Akademik dengan Keluhan Migrain pada Mahasiswa". Nutrix Journal 7, nr 2 (29.10.2023): 150. http://dx.doi.org/10.37771/nj.v7i2.943.
Pełny tekst źródłaStreszczenie:
Migraine is a neurological disease with moderate to severe pain intensity. Migraine complaints can be triggered by several trigger factors, one of which is stress. Academic stress is pressure from a subjective perspective on academic conditions. The purpose of this study was to determine the relationship between academic stress and migraine complaints of students. The design used in this research is a descriptive correlation with a cross-sectional approach. The sample in this study amounted to 45 students with a sampling technique that is purposive sampling. The result showed that 25 students (55,6%) felt severe stress and 20 (44,4%) students felt moderate stress, 35 students (77,8%) did not feel migraine complaints and 10 students (22,2%) felt migraine complaints, and there was a significant relationship between academic stress and migraine complaints with p-value =0,047. The value of r = -0,297 which means the correlation between the two variables is weak and has a negative direction. Recommendations for nursing students can maintain activities that can reduce migraine complaints such as not consuming foods containing glutamate or tyramine, For future researchers, it is advisable to research different variables and add more samples.
Keyword: Academic Stress, Migraine Complaints
Abstrak
Migrain adalah penyakit neurologis dengan intensitas nyeri sedang hingga berat. Keluhan migrain dipicu oleh beberapa faktor pencetus, salah satunya stres. Stres akademik merupakan tekanan dari perspektif secara subjektif terhadap kondisi akademik. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara stres akademik dengan keluhan migrain pada mahasiswa. Desain penelitian yang digunakan adalah deskriptif korelasi dengan pendekatan cross sectional. Sampel dalam penelitian ini berjumlah 45 mahasiswa dengan teknik sampling purposive sampling. Hasil penelitian didapati ada 25 mahasiswa (55,6%) merasakan stres berat dan 20 (44,4%) mahasiswa merasakan stres sedang, 35 (77,8%) mahasiswa tidak merasakan keluhan migrain dan 10 mahasiswa (22,2%) merasakan keluhan migrain, serta terdapat hubungan yang signifikan antara stres akademik dengan keluhan migrain dengan nilai p-value =0,047. Nilai r =-0,297 yang berarti korelasi hubungan kedua variabel lemah dan memiliki arah negatif. Rekomendasi bagi mahasiswa keperawatan dapat mempertahankan kegiatan-kegiatan yang dapat mengurangi keluhan migrain seperti tidak mengkonsumsi makanan yang mengandung glutamate atau tyramine. Bagi peneliti selanjutya, diharapkan dapat meneliti tentang variabel yang berbeda dan menambahkan jumlah sampel lebih banyak.
Kata kunci : Keluhan Migrain, Stres Akademik
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Suzuki, Keisuke, Yasuyuki Okuma, Tomoyuki Uchiyama, Masayuki Miyamoto, Ryuji Sakakibara, Yasushi Shimo, Nobutaka Hattori i in. "The prevalence, course and clinical correlates of migraine in Parkinson’s disease: A multicentre case-controlled study". Cephalalgia 38, nr 9 (26.10.2017): 1535–44. http://dx.doi.org/10.1177/0333102417739302.
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Background Previous studies have reported a lower migraine prevalence in Parkinson’s disease (PD) patients and improvements in migraine headaches after PD onset, but the clinical association of migraines with PD is unclear. Methods We analysed headache and migraine prevalence and clinical correlates in 436 PD patients (mean age, 69.3 ± 7.8 years) and 401 age- and sex-matched controls (mean age, 69.2 ± 8.6 years) in a case-controlled, multicentre study. Migraines were diagnosed by a questionnaire developed according to the International Classification of Headache Disorders, second edition. We evaluated changes in headache intensity, frequency and severity over several years around the onset of PD among PD patients with headaches or migraines, and over the past several years among control subjects with headaches or migraines. Results PD patients had lower lifetime (9.6% vs. 18.0%) and 1-year (6.7% vs. 11.0%) migraine prevalences than controls. However, lifetime (38.5% vs. 38.9%) and 1-year (26.1% vs. 26.2%) headache prevalence did not differ between PD patients and controls. After adjusting for gender, timing of the evaluation of headache changes, and recall period, PD patients with headaches or migraines exhibited a pronounced reduction in the intensity, frequency and overall severity of their headaches and migraines after the onset of PD compared with controls with headaches or migraines. PD patients with migraines exhibited a higher rate of depression and higher Pittsburgh Sleep Quality Index and PD sleep scale-2 scores than those without headaches. Conclusion While overall headache and migraine severity reduced after PD onset, the presence of migraines was associated with sleep disturbances and depression in PD patients.
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Rodríguez-Almagro, Daniel, Alexander Achalandabaso-Ochoa, Esteban Obrero-Gaitán, María C. Osuna-Pérez, Alfonso Javier Ibáñez-Vera i Rafael Lomas-Vega. "Sleep Alterations in Female College Students with Migraines". International Journal of Environmental Research and Public Health 17, nr 15 (29.07.2020): 5456. http://dx.doi.org/10.3390/ijerph17155456.
Pełny tekst źródłaStreszczenie:
Background: Many factors are thought to potentially trigger migraines, among which sleep disturbances are one of the most frequently reported. Both sleep disorders and migraines affect more women than men. This study aims to analyze sleep alterations in young adult women with migraines and how they are related to the presence, frequency, intensity, and disability of migraines in this population. Methods: Fifty-one female university students with physician-diagnosed migraines and 55 healthy female university students completed surveys assessing demographic information and frequency, intensity, and disability of migraines and sleep quality variables. Results: No differences in sleep quality were found between migraine subjects and healthy women (p = 0.815), but women with migraines presented higher daytime somnolence (p = 0.010), greater sleep disruptions (p = 0.002), and decreased sleep adequacy (p = 0.019). The presence of a migraine was significantly related to daytime somnolence (p = 0.003) and sleep disruptions (p = 0.021). Migraine-related disability was associated with sleep disruptions (p = 0.002), snoring (p = 0.016), and a decreased quantity of sleep (p = 0.040). Migraine frequency was related to sleep disturbance (p = 0.003) and snoring (p < 0.001). The intensity of migraines was associated with sleep disruptions (p = 0.004). Conclusions: Our results suggest a relationship between migraines and sleep alterations.
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Didriksen, Maria, Thomas F. Hansen, Lise W. Thørner, Kristoffer S. Burgdorf, Christian Erikstrup, Ole B. Pedersen, Helene M. Paarup i in. "Restless legs syndrome is associated with increased risk of migraine". Cephalalgia Reports 1 (1.01.2018): 251581631878074. http://dx.doi.org/10.1177/2515816318780743.
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Migraine and restless legs syndrome (RLS) are common disorders that are associated with a high level of individual suffering and major comorbidities. The aetiologies of the disorders are largely unknown, although both migraine and RLS have been linked to disturbances in the dopaminergic system and sleep issues, suggesting a relationship between the disorders. This study examines the association between RLS and migraine in a large population of otherwise healthy adults who are not taking medication. Cross-sectional study that included 20,938 participants enrolled in the Danish Blood Donor Study from 1 May 2015 to 1 February 2017. The study included complete information on migraines, the Cambridge-Hopkins RLS questionnaire, the Major Depression Inventory Scale, sex, age, body mass index (BMI), educational level, smoking status and alcohol consumption. Associations between RLS and migraine, with and without aura, were examined using multivariable logistic regression analysis. Among the participants, 4827 were self-reported migraine sufferers and 1091 were classified as suffering from RLS. Individuals with RLS had an increased risk of migraine compared to non-RLS sufferers, with an odds ratio (OR) = 1.52 (95% confidence interval: 1.33–1.73). For the investigated subtypes of migraine, this association was found to be OR = 1.55 (1.31–1.83) for migraines with aura and OR = 1.29 (1.09–1.52) for migraines without aura. We found a significantly increased occurrence of migraine in individuals with RLS. This risk was independent of sex, age, BMI, educational level, smoking status, alcohol consumption and depressive disorder. Our findings suggest that RLS and migraine may have a common aetiology.
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Mirza, Babar, i Wageha Akel. "Current Opinion in Pharmacological and Non-Pharmacological Treatment of Migraine: A Focus on Calcitonin Gene-Related Peptide". Neuro – Open Journal 8, nr 1 (31.12.2021): 5–10. http://dx.doi.org/10.17140/noj-8-136.
Pełny tekst źródłaStreszczenie:
The most common neurologic disorder is migraines. Migraine is defined as throbbing headaches that can be associated with auras. The headaches are episodic and can be debilitating in quality. Migraines can be triggered by emotional stress, lack of sleep, bright lights, loud noise, certain foods, and other environmental factors. The most effective way of preventing migraines is to avoid these triggers. A migraine can begin with prodromes or warning signs such as loss of vision, loss of motor reflexes or sensation. In this review, the types of migraine, signs and symptoms, pathways leading up to auras, and detailed pathophysiology will be discussed. The pathophysiology of a migraine consists of three different mechanisms: 1) cortical spreading depression, 2) the trigemino vascular system, and 3) sensitization. Three different treatment methods for a migraine will be discussed: 1) pharmacological, 2) non-pharmacological and 3) lifestyle modifications. Lifestyle modifications include eating a healthy diet, exercising, and maintaining proper sleep hygiene. Pharmacological treatments can be preventative or abortive. The latest migraine treatment of calcitonin gene-related peptide (CGRP) antagonist use will be discussed in this review and compared to other treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs), anticonvulsants, and Triptans. Future research methods to prevent and better treat migraine headaches are considered a hot topic in medicine and these novel methods will be discussed.
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Im, Hee-Ji, i Soo-Jin Cho. "Pharmacotherapy of migraine prevention based on the assessment of headache". Journal of the Korean Medical Association 63, nr 10 (10.10.2020): 644–49. http://dx.doi.org/10.5124/jkma.2020.63.10.644.
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Migraine as a recurrent, relapsing, and chronic disease is one of the most disabling disorders globally. Most patients are women in their reproductive age and their migraines are classified as episodic migraine. Although less than half of the episodic and most chronic migraineurs require preventive intervention, early discontinuation rates are high, owing to poor tolerability and insufficient awareness about migraine. This article aims to review the recent update of migraine prevention based on the practice guidelines for the prevention of episodic migraine published by the Korea Headache Society and the position statement of the American Headache Society in 2019. The goal of migraine prevention is to reduce migraine attack frequency by at least 50 %, the number of migraine days, and the attack severity to ultimately improve quality of life. The guidelines recommend considering the initiation of preventive medication when recurring migraines significantly interfere with daily life or when acute treatment is contraindicated or inappropriate. Preventive medications should be determined based on various qualified assessments. Pharmacologic treatments are recommended for migraine prophylaxis include antidepressant (amitriptyline), anti-epileptic drugs (topiramate, divalproex sodium), beta-blockers (propranolol, metoprolol), calcium channel blocker (flunarizine), and intramuscular injection of onabotulinumtoxin A. Furthermore subcutaneous or intravenous injection of calcitonin gene-related peptide monoclonal antibodies was recently approved as a new therapy for migraine prevention. Migraine is a chronic debilitating disorder. The initiation of evidence-based preventive management is necessary and management methods should be individually selected to improve quality of life.
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Garland, Scott G., Steven M. Smith i John G. Gums. "Erenumab: A First-in-Class Monoclonal Antibody for Migraine Prevention". Annals of Pharmacotherapy 53, nr 9 (27.02.2019): 933–39. http://dx.doi.org/10.1177/1060028019835166.
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Objective: To review the pharmacology, efficacy, and safety of the calcitonin gene-related peptide (CGRP) inhibitor erenumab for migraine preventive therapy. Data Sources: A MEDLINE/PubMed search (January 2000 to January 2019) was conducted using the keywords erenumab-aooe, erenumab, migraine, migraine prophylaxis, migraine prevention, and chronic migraine. Additional articles were identified by hand from references. Study Selection and Data Extraction: We included English-language articles (excluding poster presentations) evaluating erenumab pharmacology, efficacy, or safety in humans for migraine prevention. Data Synthesis: Erenumab is a CGRP inhibitor that inhibits vasodilation in response to acute migraines, which decreases pain perception during the migraine. Erenumab efficacy and safety has only been compared with placebo, but its reduction in monthly migraine days (MMDs) and medication response (≥50% reduction in MMDs) are comparable to current recommended off-label therapies for migraine prevention in short-term treatment studies. Additionally, erenumab is associated with low adverse event burden with no difference found compared with placebo per published clinical trials. Relevance to Patient Care and Clinical Practice: Erenumab is the first medication approved in the United States for the prevention of migraines in adults. No head-to-head data are available, but existing data suggest that erenumab is at least as effective as current off-label products and with reduced adverse effects. Conclusion: Erenumab is an effective once-monthly injectable agent for migraine prevention in patients with chronic or episodic migraine. It is also effective for patients who have previously failed migraine preventive therapy. Erenumab has a favorable adverse effect profile, which may improve patient adherence.
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Liu, Huanxian, Lu Wang, Chunfu Chen, Zhao Dong i Shengyuan Yu. "Association between Dietary Niacin Intake and Migraine among American Adults: National Health and Nutrition Examination Survey". Nutrients 14, nr 15 (25.07.2022): 3052. http://dx.doi.org/10.3390/nu14153052.
Pełny tekst źródłaStreszczenie:
Migraine is related to brain energy deficiency. Niacin is a required coenzyme in mitochondrial energy metabolism. However, the relationship between dietary niacin and migraines remains uncertain. We aimed to evaluate the relationship between dietary niacin and migraine. This study used cross-sectional data from people over 20 years old who took part in the National Health and Nutrition Examination Survey between 1999 and 2004, collecting details on their severe headaches or migraines, dietary niacin intake, and several other essential variables. There were 10,246 participants, with 20.1% (2064/10,246) who experienced migraines. Compared with individuals with lower niacin consumption Q1 (≤12.3 mg/day), the adjusted OR values for dietary niacin intake and migraine in Q2 (12.4–18.3 mg/day), Q3 (18.4–26.2 mg/day), and Q4 (≥26.3 mg/day) were 0.83 (95% CI: 0.72–0.97, p = 0.019), 0.74 (95% CI: 0.63–0.87, p < 0.001), and 0.72 (95% CI: 0.58–0.88, p = 0.001), respectively. The association between dietary niacin intake and migraine exhibited an L-shaped curve (nonlinear, p = 0.011). The OR of developing migraine was 0.975 (95% CI: 0.956–0.994, p = 0.011) in participants with niacin intake < 21.0 mg/day. The link between dietary niacin intake and migraine in US adults is L-shaped, with an inflection point of roughly 21.0 mg/day.
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Kim, Jong-Ho, Young-Suk Kwon, Jae Jun Lee, Sang-Hwa Lee i Jong-Hee Sohn. "Association between Malnutrition and Migraine Risk Assessed Using Objective Nutritional Indices". Nutrients 15, nr 17 (1.09.2023): 3828. http://dx.doi.org/10.3390/nu15173828.
Pełny tekst źródłaStreszczenie:
Dietary triggers are frequently linked to migraines. Although some evidence suggests that dietary interventions might offer a new avenue for migraine treatment, the connection between migraine and nutrition remains unclear. In this study, we explored the association between nutritional status and migraines. Clinical data spanning 11 years were sourced from the Smart Clinical Data Warehouse. The nutritional statuses of 6603 migraine patients and 90,509 controls were evaluated using the Controlling Nutrition Status (CONUT) score and the Prognostic Nutrition Index (PNI). The results showed that individuals with mild, moderate, and severe malnutrition were at a substantially higher risk of migraines than those with optimal nutrition, as determined by the CONUT score (adjusted odds ratio [aOR]: 1.72, 95% confidence interval [CI]: 1.63–1.82; aOR: 5.09, 95% CI: 4.44–5.84; aOR: 3.24, 95% CI: 2.29–4.59, p < 0.001). Similarly, moderate (PNI: 35–38) and severe (PNI < 35) malnutrition were associated with heightened migraine prevalence (aOR: 4.80, 95% CI: 3.85–5.99; aOR: 3.92, 95% CI: 3.14–4.89, p < 0.001) compared to those with a healthy nutritional status. These findings indicate that both the CONUT and PNI may be used as predictors of migraine risk and underscore the potential of nutrition-oriented approaches in migraine treatment.
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Rajalekshmi K, Dhanya Dharman, Deepa Manohar, Shaiju S Dharan, Dhanya S S i Bismi S. "A survey on functioning of male and female with migraine". International Journal of Research in Hospital and Clinical Pharmacy 1, nr 3 (1.08.2019): 85–87. http://dx.doi.org/10.33974/ijrhcp.v1i3.127.
Pełny tekst źródłaStreszczenie:
Migraines are severe, recurring, and painful headaches. The extreme pain have that migraines cause can last for hours or even days. Migraines can follow an aura of sensory disturbances followed by a severe headache that often appears on one side of the head. Objective of the study include; To find out whether male and female are more prone to develop migraine, To evaluate which triggering factors contributes to migraine and To evaluate the people taking OTC for migraine. A Prospective survey will be carried out in 75 peoples using the information’s gathered from students in Pharmacy colleges in Trivandrum. This study provides the prevalence of migraine headache. Past history, medication usage, diagnosis, treatment, triggering factors, physical and intellectual activities was collected, analysed properly and response is recorded. These collected data will be subjected to statistical analysis. In the current research, a survey on functioning of male and female with migraine was formulated. Among the respondents about 18-35 age group is commonly affected migraine with 98.7%(n=74). Approximately, 63.5%(n=47) female are affected with migraine than 36.5%(n=27) male. About 11.16%(n=8) of patients taken prescription drugs and 52.2%(n=48) are taken over-the-counter medicines. Migraine worsened in 77.20%(n=48) patients with stress, 50%(n=33) bright sunshine, 33.30%(n=22) loud noise and others have air travel, fatigue, certain smells and perfume. The goal of management is to reduce frequency and severity of episodes in males and females. Also limit the impact of this chronic pain condition.
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Fila, Michal, Cezary Chojnacki, Jan Chojnacki i Janusz Blasiak. "Is an “Epigenetic Diet” for Migraines Justified? The Case of Folate and DNA Methylation". Nutrients 11, nr 11 (14.11.2019): 2763. http://dx.doi.org/10.3390/nu11112763.
Pełny tekst źródłaStreszczenie:
Migraines are a common disease with limited treatment options and some dietary factors are recognized to trigger headaches. Although migraine pathogenesis is not completely known, aberrant DNA methylation has been reported to be associated with its occurrence. Folate, an essential micronutrient involved in one-carbon metabolism and DNA methylation, was shown to have beneficial effects on migraines. Moreover, the variability of the methylenetetrahydrofolate reductase gene, important in both folate metabolism and migraine pathogenesis, modulates the beneficial effects of folate for migraines. Therefore, migraine could be targeted by a folate-rich, DNA methylation-directed diet, but there are no data showing that beneficial effects of folate consumption result from its epigenetic action. Furthermore, contrary to epigenetic drugs, epigenetic diets contain many compounds, some yet unidentified, with poorly known or completely unknown potential to interfere with the epigenetic action of the main dietary components. The application of epigenetic diets for migraines and other diseases requires its personalization to the epigenetic profile of a patient, which is largely unknown. Results obtained so far do not warrant the recommendation of any epigenetic diet as effective in migraine prevention and therapy. Further studies including a folate-rich diet fortified with valproic acid, another modifier of epigenetic profile effective in migraine prophylaxis, may help to clarify this issue.
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Shill, Sajal Kumar, Md Abbas Uddin, Shah Didar Imam i Ayesha Hasina. "Association between serum total cholesterol and migraine". Central Medical College Journal 5, nr 1 (12.06.2022): 41–46. http://dx.doi.org/10.3329/cemecj.v5i1.60204.
Pełny tekst źródłaStreszczenie:
Background: There is increasing evidence that migraine with aura is associated with increased risk of ischemic stroke and other vascular disease events. Furthermore migraine has been associated with increased prevalence of specific cardiovascular risk factors, such as hypercholesterolemia has been proposed.
Aims and objectives: The present study is aimed at to evaluate the association between serum total cholesterol and migraine.
Material and methods: This observational cross sectional study was carried out in Neurology Department in Mymensingh Medical College from December 2016 to November 2018 for a period of 2 years. Patients were selected by purposive sampling. Among 100 patients, 50 grouped as migraineur and 50 grouped as non-migraineur for the study.
Results: Serum total cholesterol was significantly higher in migraine than non-migraine. Serum total cholesterol was significantly higher in late age of migraine group and migraine with aura.
Conclusion: Elevated level of serum total cholesterol was associated with migraine than non-migraine. Serum total cholesterol was significantly higher in late age of migraine group and migraine with aura.
Central Medical College Journal Vol 5 No 1 Jan 2021 PP 41-46
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Altalib, HH, BT Fenton, J. Sico, JL Goulet, H. Bathulapalli, A. Mohammad, J. Kulas i in. "Increase in migraine diagnoses and guideline-concordant treatment in veterans, 2004–2012". Cephalalgia 37, nr 1 (30.09.2016): 3–10. http://dx.doi.org/10.1177/0333102416631959.
Pełny tekst źródłaStreszczenie:
Background and aim Health administrators, policy makers, and educators have attempted to increase guideline adherence of migraine medications while reducing inappropriate use of opioid- and barbiturate-containing medications. We evaluated the burden of migraine and proportion of guideline-concordant care in a large, national health care system over time. Methods We conducted a time-series study using data from the Veterans Health Administration (VHA) electronic health record. Veterans with migraines were identified by ICD-9 code (346.X). Prescriptions and comorbid conditions were evaluated before and after migraine diagnosis. Chi-square tests and logistic regression were performed. Results A total of 57,064 veterans were diagnosed with migraine headache (5.3%), with women significantly more likely diagnosed (11.6% vs. 4.4%, p < 0.0001). The number of veterans diagnosed with migraine has significantly increased over the years. By 2012, triptans were prescribed to 43% of people with migraine, with no difference by gender. However, triptan prescriptions increased from 2004 to 2012 in men, but not women, veterans. Preventive medicines showed a significant increase with the year of migraine diagnosis, after controlling for age, sex, race, and for comorbidities treated with medications used for migraine prevention. Conclusions The burden of migraines is increasing within the VHA, with a corresponding increase in the delivery of guideline-concordant acute and prophylactic migraine-specific medication.
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Ishii, Masakazu, Hirotaka Katoh, Hideyo Kasai i Masaaki Ishibashi. "Relationship between migraine and internet addiction in pharmacy students". Japan Journal of Research 1, nr 1 (30.04.2020): 1–6. http://dx.doi.org/10.33425/2690-8077.1004.
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Background: In recent years, with the rapid popularization of the Internet, lifestyle disturbances, such as insufficient sleep due to excessive use of the Internet, is of concern. Sleep problems are known to trigger migraines. To clarify the relationship between migraine and Internet addiction, a questionnaire survey was conducted for pharmacy students at university. Methods: Internet addiction symptoms were assessed using the Internet Addiction Test (IAT), and migraine was evaluated using modified Japanese migraine screening. Continuous variables were analysed using the unpaired Student’s t-test or one-way analysis of variance followed by multiple Turkey's comparison tests. Categorical variables were analysed by the χ2 test. Results: The recovery rate was 98.9% (442 / 447 students). Of the 288 students who had headaches in the past 3 months, 145 students (32.8%, 145/442 students) were judged as having migraines by migraine screening. Sleep problems (62.1%) were observed in the migraine group. Moreover, sleep deprivation due to headache was noted in 31.7% of the migraine group. The percentage of students with Internet addiction in the migraine group was significantly higher than that in the other headache group or no headache group. Conclusions: Internet addiction was associated with the presence/absence of migraine in pharmacy students at university
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Tan, Rhea, i Hugh Markus. "THE SPECTRUM OF MIGRAINE IN 306 PATIENTS WITH CADASIL". Journal of Neurology, Neurosurgery & Psychiatry 86, nr 11 (14.10.2015): e4.162-e4. http://dx.doi.org/10.1136/jnnp-2015-312379.7.
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Migraine is often the first manifestation of CADASIL, the commonest monogenic cause of stroke. We aimed to determine the pattern of migraine, and its relationship with other features of CADASIL. Of 314 patients seen in a national referral clinic, 71.6% reported migraines. Migraine was the first feature of CADASIL in 67.6% of symptomatic individuals. Females (81.7%) were more likely to develop migraine than males (66.9%), and suffered migraine at an earlier age (27.0±12.7 vs 32.3±13.2 years, p=0.004).89.8% of migraneurs experienced aura. Where aura occurred it was visual in 69.7% sensory 58.7%, dysphasic 30.3%, confusional 17.9%, motor 15.9% and sensorimotor 9.95%.A self-limiting encephalopathy occurred in 33 patients (10.8%); 72.7% of these evolved from a migraine episode. Patients with confusional migraines were more likely to develop encephalopathy (OR=3.93, 95% CI=1.51–9.73, p=0.0024).Non-migraneurs had a higher cumulative risk of stroke than those migraneurs (HR 2.13, 95% CI 1.53–2.96, p=6.8×10−6).In conclusion, the spectrum of migraine in CADASIL differs from that in the general population. Acute encephalopathy is a common feature of CADASIL and usually evolves from a migraine episode. Non-migraneurs have a higher risk of developing stroke, however the reasons for this are not well understood.
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Yamanaka, Gaku, Shinji Suzuki, Natsumi Morishita, Mika Takeshita, Kanako Kanou, Tomoko Takamatsu, Shinichiro Morichi i in. "Experimental and Clinical Evidence of the Effectiveness of Riboflavin on Migraines". Nutrients 13, nr 8 (29.07.2021): 2612. http://dx.doi.org/10.3390/nu13082612.
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Riboflavin, a water-soluble member of the B-vitamin family, plays a vital role in producing energy in mitochondria and reducing inflammation and oxidative stress. Migraine pathogenesis includes neuroinflammation, oxidative stress, and mitochondrial dysfunction. Therefore, riboflavin is increasingly being recognized for its preventive effects on migraines. However, there is no concrete evidence supporting its use because the link between riboflavin and migraines and the underlying mechanisms remains obscure. This review explored the current experimental and clinical evidence of conditions involved in migraine pathogenesis and discussed the role of riboflavin in inhibiting these conditions. Experimental research has demonstrated elevated levels of various oxidative stress markers and pro-inflammatory cytokines in migraines, and riboflavin’s role in reducing these marker levels. Furthermore, clinical research in migraineurs showed increased marker levels and observed riboflavin’s effectiveness in reducing migraines. These findings suggest that inflammation and oxidative stress are associated with migraine pathogenesis, and riboflavin may have neuroprotective effects through its clinically useful anti-inflammatory and anti-oxidative stress properties. Riboflavin’s safety and efficacy suggests its usefulness in migraine prophylaxis; however, insufficient evidence necessitates further study.
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Chen, Chien-Hua, Cheng-Li Lin i Chia-Hung Kao. "Gallbladder Stone Disease Is Associated with an Increased Risk of Migraines". Journal of Clinical Medicine 7, nr 11 (21.11.2018): 455. http://dx.doi.org/10.3390/jcm7110455.
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Background: Several pathophysiological mechanisms are shared in both gallbladder stone disease (GSD) and migraines. We assessed the migraine risk for patients diagnosed with GSD. Methods: We identified 20,427 patients who were diagnosed with GSD between 2000 and 2011 from Taiwan’s National Health Insurance Research Database (NHIRD) as the study cohort. We randomly selected 81,706 controls from the non-GSD population with frequency matching by age and index year for the control cohort. All patient cases were followed until the end of 2011 to measure the incidence of migraines. Results: The cumulative incidence of migraines was greater in patients with GSD than in those without GSD (log-rank test: p < 0.001). The risk of migraine (3.89 vs. 2.30 per 10,000 person-years, adjusted hazard ratio (aHR) = 1.56, 95% confidence interval (CI) = 1.41–1.73) was greater for the GSD cohort than that for the non-GSD cohort. The risk of migraine increased with the time of follow-up after a diagnosis of GSD. The risk of migraine contributed by GSD was greater for all age groups. The risk of migraine for GSD patients with depression (aHR = 2.89, 95% CI = 2.21–3.77), anxiety (aHR = 2.07, 95% CI = 1.58–2.70), and coronary artery disease (CAD) (aHR = 2.05, 95% CI = 1.69–2.48) tended to be greater than that for GSD patients without depression (aHR = 1.54, 95% CI = 1.39–1.72), anxiety (aHR = 1.62, 95% CI = 1.46–1.81), and CAD (aHR = 1.65, 95% CI = 1.47–1.85), respectively. Compared with the patients without GSD, the risk of developing migraines was greater in those GSD patients either with (aHR = 1.39, 95% CI = 1.19–1.63) or without (aHR = 1.67, 95% CI = 1.48–1.88) cholecystectomy. Compared with the GSD patients that have not had a cholecystectomy, the risk of developing migraines was lower in the GSD patients that had a cholecystectomy (aHR = 0.83, 95% CI = 0.69–0.99). Conclusions: GSD is associated with an increased risk of migraines in the Taiwanese population, but the risk diminishes after a cholecystectomy. Furthermore, in the development of migraines, GSD is synergic with some migraine-associated comorbidities, such as CAD, depression, and anxiety. Further study is necessary to clarify whether GSD is a causal risk factor for migraine.
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Sileno, Sean M., Yan Bi, Sean M. Dorenkott, Mohamed Omer, Ahmed Salih, Hassan M. Ghoz, Jose R. Valery i in. "Comparison of Migraine Characteristics in Patients With and Without Inflammatory Bowel Disease: A Retrospective Cohort Study". Journal of Primary Care & Community Health 14 (styczeń 2023): 215013192311643. http://dx.doi.org/10.1177/21501319231164307.
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Background: Survey studies have found an increased prevalence of migraine in patients with inflammatory bowel disease (IBD). However, the clinical characteristics of migraines in this population are unknown. We conducted a retrospective medical record review study to characterize migraines in the IBD population. Methods: Six hundred seventy-five migraine patients (280 with IBD, 395 without IBD) who were evaluated at Mayo Clinic Rochester, Mayo Clinic Arizona, or Mayo Clinic Florida between July 2009 and March 2021 were included. Patients with ICD codes for migraine and either Crohn’s disease (CD) or ulcerative colitis (UC) were selected. Electronic health care records were reviewed. Patients confirmed to have IBD and migraine were included. Demographic, IBD, and migraine characteristics were collected. Statistical analysis was completed using SAS. Results: Patients with IBD were less often male (8.6% vs 21.3%, P < .001) and had a higher Charlson Comorbidity Index (>2: 24.6% vs 15.7%, P = .003); 54.6% had CD and 39.3% had UC. Patients with IBD had migraine with aura and without aura more frequently ( OR 2.20, P < .001 and OR 2.79, P < .001, respectively) than non-IBD patients. Additionally, those with IBD less commonly had chronic migraine (OR 0.23, P < .001) and less commonly had chronic migraine or treatment for migraine (ORs 0.23-0.55, P ≤ .002). Conclusions: Migraine with and without aura have increased prevalence in IBD patients. Further study of this topic will be helpful to clarify the prevalence of migraine, establish this population’s response to treatment, and better understand the reason(s) for a low rate of treatment.
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Rasoul, Abdulrahman. "OXIDATIVE STRESS STATUS IN SERUM OF MIGRAINEURS IN ERBIL CITY-IRAQ". JOURNAL OF SULAIMANI MEDICAL COLLEGE 13, nr 3 (21.09.2023): 8. http://dx.doi.org/10.17656/jsmc.10415.
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BackgroundMigraine is one of the neurological disorders whose etiology remains elusive. Increased oxidative stress may be associated with migraine. Oxidative stress may play an important role in patients with migraine, and it can reflect the ability of tissues to free radical damage.
ObjectivesTo determine the oxidative stress markers levels in migraine patients’ serum. This study also included the use of oxidative stress indicators to diagnose migraines.
Materials and MethodsA total of 180 subjects (100 migraines and 80 healthy controls) were included in the study; nitric oxide (NO) metabolites, malondialdehyde (MDA), and superoxide dismutase (SOD) were measured in serum.
ResultsIn migraineurs, the levels of SOD, NO, and MDA were significantly higher when compared to healthy controls. There was a significant positive correlation between NO with MDA and SOD. Roc curve showed that NO was a useful marker for the diagnosis of migraine. Binary logistic regression documented that NO was negatively affect the life of migraineurs.
ConclusionTherefore, oxidative stress has a role in the pathophysiology of migraine, and NO may serve as a useful diagnostic marker in migraine patients.
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Sati, Vaishali, Reenoo Jauhari, Nahid Rao, Pallavi Godiyal i Aseem Babbar. "MELATONIN: ROLE IN THE PROPHYLAXIS OF MIGRAINE". Journal of Applied Pharmaceutical Sciences and Research 5, nr 2 (23.09.2022): 17–27. http://dx.doi.org/10.31069/japsr.v5i2.03.
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Melatonin and migraine have been linked in most ways, from mechanisms to treatment. Migraine is one of the common neurological diseases and it is characterized by throbbing unilateral headache attacks. Migraine is an issue for both individuals and society. Migraine can lead to reduced work productivity and a flawed family and social life. It has been suggested that melatonin plays a key therapeutic role in treating migraines and several other types of headaches. Early and exact diagnosis is essential in enhancing treatment and in preventing progression. This review aimed to evaluate the available evidence related to the efficacy and safety of melatonin in the prophylaxis and prevention of migraine. Research in regard the administration of melatonin found it safe in migraine patients, with few or no side effects. This review concluded that Melatonin can be considered a safe integrative prophylactic treatment for children, adults and menstrual-related migraines, thus improving outcomes related to patient’s quality of life and patient-centered care. However, further studies and evaluation is required to confirm its effects.This review aimed to evaluate the available evidence related to the efficacy and safety of melatonin in migraine prophylaxis. Melatonin and migraine have been linked in a majority of ways, from mechanisms to treatment. Melatonin is an endogenous hormone and is secreted by the pineal gland. It plays an important role in regulating circadian rhythm and the sleep-wake cycle. It has been proposed for migraine prevention due to its anti-inflammatory effects against calcitonin gene-related peptides and other pro-inflammatory mediators in vitro, and its pro-regulatory effect on the circadian rhythm. Also, low melatonin levels have been reported in serum and urine due to hypothalamic dysfunction in patients with migraine. Hence, in this article, we review those papers describing the results of the administration of melatonin in humans for therapeutic purposes in treating migraines.This narrative literature review was based on studies on Melatonin's effectiveness, safety and tolerability for the prophylactic and preventive treatment of migraine in children and adolescents and menstruating women. The literature search was conducted using the Google Scholar and PubMed database and included articles published up to December 2021, utilizing the keywords: “melatonin”, “migraine”, “melatonin and migraine”, and “prophylaxis of migraine”. Observational studies, randomized controlled trials (RCTs), case reports and systematic reviews were included. The articles focusing on the latest medication for preventing migraines were also reviewed.
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Lee, Sang-Hwa, Jong-Ho Kim, Young-Suk Kwon, Jae-June Lee i Jong-Hee Sohn. "Risk of Vestibulocochlear Disorders in Patients with Migraine or Non-Migraine Headache". Journal of Personalized Medicine 11, nr 12 (8.12.2021): 1331. http://dx.doi.org/10.3390/jpm11121331.
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Headaches, especially migraines, have been associated with various vestibular symptoms and syndromes. Tinnitus and hearing loss have also been reported to be more prevalent among migraineurs. However, whether headaches, including migraine or non-migraine headaches (nMH), are associated with vestibular and cochlear disorders remains unclear. Thus, we sought to investigate possible associations between headache and vestibulocochlear disorders. We analyzed 10 years of data from the Smart Clinical Data Warehouse. In patients with migraines and nMH, meniere’s disease (MD), BPPV, vestibular neuronitis (VN) and cochlear disorders, such as sensorineural hearing loss (SNHL) and tinnitus, were collected and compared to clinical data from controls who had health check-ups without headache. Participants included 15,128 with migraines, 76,773 patients with nMH and controls were identified based on propensity score matching (PSM). After PSM, the odds ratios (OR) in subjects with migraine versus controls were 2.59 for MD, 2.05 for BPPV, 2.98 for VN, 1.74 for SNHL, and 1.97 for tinnitus, respectively (p < 0.001). The OR for MD (1.77), BPPV (1.73), VN (2.05), SNHL (1.40), and tinnitus (1.70) in patients with nMH was also high after matching (p < 0.001). Our findings suggest that migraines and nMH are associated with an increased risk of cochlear disorders in addition to vestibular disorders.
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Sanoeva, Matlyuba, i Gulova Munisakhon. "Comparative analysis of cognitive function at vascular complications of migraine. Diagnosis and clinical approach". BIO Web of Conferences 121 (2024): 03014. http://dx.doi.org/10.1051/bioconf/202412103014.
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Migraine affects 11-15% of the adult population, frequent and prolonged migraine attacks, untimely correction, the absence of preventive measures can form vascular complications with the development of cognitive dysfunctions. The aim of this study was to study and analyze cognitive function in various variants of the course of complicated migraines in a comparative aspect. We studied 378 (100%) patients with various options for the course of migraine. Of these, 78 (20.6%) examined with migraine status, 82 (21.7%) with chronic migraine, 52 (13.8%) with migraine strokes, 87 (23.0%) chemoprophylaxis with migraine, considered as the main group, and the comparative group included 79 (20.9%) patients with uncomplicated migraine. The study demonstrate that cognitive dysfunction complicated by migraine develops due to cerebral vascular reactions modelled on vasodilation / vasoconstriction against the background of migraine attacks that cause hypoxia and then local ischemia with the formation of encephalomalacia in “strategic areas” and can be considered as a predisposition of patients with migraine to vascular dementia.
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Younis, Ali, Yahya Qasem i Ali Neamat Sulaiman Alallaf. "The Frequency of Fibromyalgia in Migraine Patients". Open Access Macedonian Journal of Medical Sciences 10, B (25.01.2022): 260–64. http://dx.doi.org/10.3889/oamjms.2022.8246.
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BACKGROUND: Fibromyalgia (FM) is a prevailing debilitating ailment that has been described in patients with migraines in several investigations. AIM: The study aimed to investigate the frequency of FM in migraine patients and to study the characteristics of migraine patients with comorbid FM. METHODS: This case–control study was piloted in the Neurology Unit, Department of Medicine in Ibn Sina Teaching Hospital in Mosul, Iraq, between March and November 2020. One hundred consecutive patients with migraine and 100 healthy controls were included in this study. The sociodemographic and headache characteristics of the patients were recorded. RESULTS: The frequency of FM was statistically higher among participants with migraines (27%) when compared to the controls (5%). Migraine patients with FM had a substantially older mean age and a higher ratio of female gender than migraine patients without FM. FM was found to be more common in patients without versus with aura. Patients with comorbid FM had greater headache frequency (p = 0.0002), headache intensity (p = 0.007), and higher scores on the “Headache Impact Test (HIT-6)” (p = 0.0001). CONCLUSIONS: There is a high frequency of FM in patients with migraines. Patients with coexistent “FM” and “migraine” tended to have more depressive symptoms, greater headache intensity, headache frequency, and when compared to healthy people, they are more likely to have a significant headache-related disability.
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Datul Hasanah, Mauli, Ima Maria, Mirna Marhami Iskandar, Attiya Istarini i Patrick William Gading. "HUBUNGAN SCREEN TIME DENGAN KEJADIAN MIGRAIN PADA MAHASISWA KEDOKTERAN UNIVERSITAS JAMBI ANGKATAN 2018". Journal of Medical Studies 2, nr 1 (11.05.2022): 1–12. http://dx.doi.org/10.22437/joms.v2i1.18088.
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ABSTRACT
Background: Migraine is one of the most common primary headache complaints. Migraine can occur due to trigger factors including foods with certain ingredients (such as tyramine, chocolate), menstrual cycles, weather, sleep patterns, bright light, and screen time. Screen time is the total time spent viewing or watching gadget screens such as televisions, computers (laptops), smartphones, tablets and video games. Objectives: To determine the relationship between screen time and the incidence of migraine in medical students at Jambi University. Methods: This research is a quantitative analytic study with a cross sectional design. Respondents consisted of 93 medical students at Jambi University Batch 2018 who were taken by the total sampling method and had met the inclusion and exclusion criteria. Screen time data and migraine incidence were assessed using a questionnaire. Analysis of the relationship between the two variables was tested by chi-square test and processed with SPSS version 25. Results: The results showed that there was a significant relationship between screen time and the incidence of migraine. Conclusions: the longer the use of screen time, the higher the incidence of migraine in medical students at Jambi University batch 2018.
Keywords: Migraine, Screen time
ABSTRAK
Latar belakang: Migrain merupakan salah satu keluhan nyeri kepala primer yang paling sering ditemukan. Kejadian migrain dapat terjadi karena adanya faktor pemicu diantaranya makanan dengan kandungan tertentu (seperti tiramin, cokelat), siklus menstruasi, cuaca, pola tidur, cahaya yang terang, dan screen time. Screen time adalah waktu total yang dihabiskan untuk melihat atau menonton layar gadget seperti televisi, komputer (laptop), smartphone, tablet dan video game. Tujuan: Mengetahui hubungan antara screen time dengan kejadian migrain pada mahasiswa kedokteran Universitas Jambi. Metode: Penelitian ini merupakan penelitian analitik kuantitatif dengan desain cross sectional. Responden terdiri dari 93 mahasiswa kedokteran Universitas Jambi Angkatan 2018 yang diambil dengan metode total sampling dan telah memenuhi kriteria inklusi dan eksklusi. Data screen time dan kejadian migrain dinilai dengan kuisioner. Analisis hubungan antara dua variabel diuji dengan uji chi-square dan diolah dengan SPSS versi 25. Hasil: Hasil penelitian didapatkan adanya hubungan antara screen time dengan kejadian migrain. Kesimpulan: Semakin lama penggunaan screen time maka akan meningkatkan kejadian migrain pada mahasiswa kedokteran Universitas Jambi angkatan 2018.
Kata kunci: Migrain, Screen time
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Ostashko, M. P., i T. I. Nasonova. "MARKERS OF NEUROVISULATION IN MIGRAINE DIAGNOSTICS". PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse, nr 5(57) (24.04.2019): 108–13. http://dx.doi.org/10.21802/10.21802/2304-7437-2019-5(57)-108-113.
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In clinical medicine, the diagnosis of migraine is based on anamnesis and symptoms, and instrumental diagnostic methods are considered non-informative. Numerous studies of the brain, during headaches and between them, have made a significant contribution to understanding the pathophysiology of migraines. Structural and functional changes in the migraine brain are revealed by advanced magnetic resonance imaging techniques, and attempts to detect the visualization markers of this disease progressively increase. This overview article aims to summarize the results of recent studies that reflect achievements in understanding the pathophysiology of migraine, as well as the possibility of using neuroimaging techniques in diagnosing migraines.
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Ostashko, M. P., i T. I. Nasonova. "MARKERS OF NEUROVISULATION IN MIGRAINE DIAGNOSTICS". PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Pulse, nr 5(57) (24.04.2019): 108–13. http://dx.doi.org/10.21802/2304-7437-2019-5(57)-108-113.
Pełny tekst źródłaStreszczenie:
In clinical medicine, the diagnosis of migraine is based on anamnesis and symptoms, and instrumental diagnostic methods are considered non-informative. Numerous studies of the brain, during headaches and between them, have made a significant contribution to understanding the pathophysiology of migraines. Structural and functional changes in the migraine brain are revealed by advanced magnetic resonance imaging techniques, and attempts to detect the visualization markers of this disease progressively increase. This overview article aims to summarize the results of recent studies that reflect achievements in understanding the pathophysiology of migraine, as well as the possibility of using neuroimaging techniques in diagnosing migraines.
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Shaterian, Negar, Negin Shaterian, Aref Ghanaatpisheh, Farnaz Abbasi, Sara Daniali, Maryam Jalali Jahromi, Mohammad Sadegh Sanie i Amir Abdoli. "Botox (OnabotulinumtoxinA) for Treatment of Migraine Symptoms: A Systematic Review". Pain Research and Management 2022 (31.03.2022): 1–15. http://dx.doi.org/10.1155/2022/3284446.
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Background. Migraine is one of the most common types of headache, and it is the second most common cause of neurological disorders, with an annual prevalence of about 15% of the population. This study aimed to evaluate the effect of BoNT-A on the duration and intensity of migraine attacks. In addition, we investigated the effective injection sites. Methods. According to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, we searched online databases, including Web of Science, PubMed, EMBASE, Scopus, Cochrane Library, ProQuest, ClinicalTrials.gov, and Google Scholar from 2011 to 2021. Results. A total of 24 articles were included in the study. The use of BoNT-A in individuals suffering from chronic migraine (CM) decreases the frequency of migraine attacks per month, pain intensity, medication use, emergency visits, and migraine-related disabilities. The BoNT-A was well tolerated and leads to improved performance and better quality of life (QoL). Overall, treatment with BoNT-A in adults with CM is beneficial. In addition, the use of BoNT-A in individuals with vestibular migraine (VM) reduces the frequency of migraines and brings about the improvement of disability status caused by migraine headaches. Meanwhile, the use of BoNT-A reduces the frequency of migraine attacks per month among individuals with chronic refractory migraine (CRM). Conclusions. The use of BoNT-A is a low-cost option for the treatment of various kinds of migraines, including chronic, episodic, unilateral, and vestibular types. BoNT-A can reduce the frequency of migraine attacks per month and diminish the severity of pain.
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Alzahrani, Fahad, Yaser M. Alahmadi, Sultan S. Al Thagfan, Sultan Alolayan i Hossein M. Elbadawy. "Migraine Management in Community Pharmacies: Knowledge, Attitude and Practice Patterns of Pharmacists in Saudi Arabia". Pharmacy 11, nr 5 (24.09.2023): 155. http://dx.doi.org/10.3390/pharmacy11050155.
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In Saudi Arabia, community pharmacies offer healthcare services for different conditions. However, clarity of the competence of pharmacists in managing migraines is lacking. This study aimed to explore the current knowledge, attitude, and practice patterns of community pharmacists concerning migraine management in the northwestern part of Saudi Arabia. A cross-sectional study was carried out between June and September 2022 among 215 Saudi community pharmacists. Data analysis was performed by descriptive and inferential statistics using SPSS version 27. Most community pharmacists (87.9%) feel that migraine management is essential to their practice, and 83.3% suggest between one and five over-the-counter (OTC) migraine products daily. Among the study pharmacists, 83.7% feel migraine patients should try OTC before prescription medications. Only 9.3% of the community pharmacists do not believe that migraine is a neurological disorder. The medications most prescribed for migraine were triptans, representing 52.1% of prescriptions. There were significant differences between the gender of the pharmacists and their knowledge, attitude, and practice overall score (p-value = 0.04). Male pharmacists exhibited higher knowledge, attitude, and practice scores than female pharmacists. Although many community pharmacists acknowledge their expertise and involvement in managing migraines, there is a requirement for further education and training to enhance their capacity to offer complete care to migraine patients. Pharmacists should also consider non-pharmacological interventions and complementary therapies when treating migraine symptoms.
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Penhollow, Tina M., i Alexandra C. Mielke. "Aromatherapy: an alternative treatment for migraine headaches". International Physical Medicine & Rehabilitation Journal 9, nr 1 (22.01.2024): 1–4. http://dx.doi.org/10.15406/ipmrj.2024.09.00365.
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Neurological disorders are recognized as one of the leading causes of death and disability worldwide. Migraines are a neurological disorder that is often accompanied by symptoms such as pain, light and sound sensitivity, nausea, vomiting, and changes in vision. There are many challenges to managing episodic and chronic migraines. There are several non-modifiable and modifiable risk factors associated with migraine onset. Pharmacological management has been shown to be effective. Research has also shown that aromatherapy can have a positive impact on preventing and managing migraine headaches. The purpose of this mini review is to provide current data on migraines and to offer options beyond prescribed pharmaceutical medication to alleviate symptoms of this disorder. It is important to offer alternative preventative solutions to manage migraine disorders.
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Oka Adnyana, I. Made, Richard Suherlim i I. Putu Eka Widyadharma. "Various Trigger Factors of Migraine: A Review of Pathophysiology and Mechanism". International Journal of Research and Review 11, nr 4 (20.04.2024): 347–57. http://dx.doi.org/10.52403/ijrr.20240439.
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Migraine is a high prevalence primary headache. Global epidemiological data from 132 countries in 2016 shows an estimated 1.04 billion people have migraine. Epidemiological data in Bali based on research by Adnyana in 2012 showed 23.7% nursing students had migraines. Although migraine can occur spontaneously, many migraine attacks are triggered by certain trigger factors. The trigger factors for migraine are various, ranging from foods, hormonal disorders, stress, sleep disorders, and environmental factors. Each of these factors has its own mechanism that contributes to the pathophysiology of migraine. Based on scientific data, some factors have strong supporting evidence regarding their correlation with migraine, but some others are only suggestive and not supported by scientific evidence. Factors that have obvious involvement with migraine are hormonal factors, stress, and sleep. Some types of foods such as chocolate and caffeine have a migraine trigger effect, but they can also treat migraine. It is recommended for patients to be able to identify factors that may trigger headache attacks, so that they can reduce the frequency of attacks in chronic migraine patients. Keywords: Migraine, Trigger, Mechanism
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Adeney, KL, JL Flores, JC Perez, SE Sanchez i MA Williams. "Prevalence and Correlates of Migraine Among Women Attending a Prenatal Care Clinic in Lima, Peru". Cephalalgia 26, nr 9 (wrzesień 2006): 1089–96. http://dx.doi.org/10.1111/j.1468-2982.2006.01171.x.
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Migraine headaches are among the leading causes of disability in the world. The burden of migraines is highest in women of reproductive age. This cross-sectional study characterized the prevalence, symptoms and correlates of migrainous headaches in 154 pregnant women attending a prenatal care clinic in Lima, Peru. Lifetime prevalence of migraine defined by modified IHS criteria was 9.1± (95± CI 4.6–13.6). When probable migraines were included, the lifetime prevalence of migraine in this population was 29.2± (95± CI 22.0–36.4). Migraine headaches were associated with a maternal history of headache, childhood carsickness, a diagnosis of allergies, and a high frequency of fatigue. Although headache-related disability was low in terms of missed work and recreation, high rates of headache pain and medicinal use reflect the true impact on this population.
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Kim, Seonghoon, Si Baek Lee, Yun Jeong Hong, Yongbang Kim, Kyungdo Han i Jeong Wook Park. "The influence of endogenous and exogenous hormonal factors on migraine in spontaneous postmenopausal women: A nationwide population-based study in South Korea". Cephalalgia 42, nr 4-5 (27.09.2021): 376–84. http://dx.doi.org/10.1177/03331024211044441.
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Background Hormonal and menstrual factors are known to influence migraines in women. However, studies in the postmenopausal period are relatively insufficient for clinical translation. This study investigated the influence of endogenous and exogenous hormonal factors on migraines in spontaneous menopausal women. Methods We obtained and analyzed the data related to hormonal factors from the Korean Health Examination database. A migraine diagnosis was identified using the Korean National Health Insurance Service database between 2009 and 2018. We observed migraine occurrence in spontaneous postmenopausal women. Study populations were divided into two groups depending on new diagnosis of migraine during the follow up periods. We investigated the association between endogenous and exogenous hormonal factors and migraine. Results 1,114,742 spontaneous postmenopausal women were enrolled. Migraine risk tended to increase in the shorter lifetime number of years of menstruation group compared to the group with lifetime number of years of menstruation ≥40 years. All of the hormone replacement therapy (HRT) groups showed higher risk compared with the non-HRT group. Migraine risk tends to increase with greater postmenopausal years compared to the postmenopausal <5 years group. Conclusion Our study suggests that female hormonal factors, including endogenous and exogenous estrogen exposure, may be associated with migraine occurrence in spontaneous menopausal women.