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1

Khaustov, A. I., G. G. Boyarsky, and K. V. Krotov. "Designing of a Micropump System for Circulatory Support." Journal of the Russian Universities. Radioelectronics 25, no. 5 (2022): 104–12. http://dx.doi.org/10.32603/1993-8985-2022-25-5-104-112.

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Introduction. Support systems currently used in modern cardiac surgery to provide partial or complete, permanent or temporary replacement of cardiac function are frequently characterized by large dimensions, thus requiring major surgical interventions. Low invasiveness can be ensured by reducing the size of the implanted part of such systems, allowing these devices to be inserted through the femoral artery.Aim. Development of a minimally invasive micropump system to support blood circulation.Materials and methods. Based on the analysis of implementation of micropump circulatory support systems
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Jin, Wenzui, Yimin Guan, Qiushi Wang, et al. "A Smart Active Phase-Change Micropump Based on CMOS-MEMS Technology." Sensors 23, no. 11 (2023): 5207. http://dx.doi.org/10.3390/s23115207.

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The rational integration of many microfluidic chips and micropumps remains challenging. Due to the integration of the control system and sensors in active micropumps, they have unique advantages over passive micropumps when integrated into microfluidic chips. An active phase-change micropump based on complementary metal–oxide–semiconductor–microelectromechanical system (CMOS-MEMS) technology was fabricated and studied theoretically and experimentally. The micropump structure is simple and consists of a microchannel, a series of heater elements along the microchannel, an on-chip control system,
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Wang, Bao Wei, Xiang Cheng Chua, and Long Tu Li. "A Piezoelectric Micropump Based on MEMS Fabrication." Key Engineering Materials 368-372 (February 2008): 215–17. http://dx.doi.org/10.4028/www.scientific.net/kem.368-372.215.

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This paper presents a valve-less micropump which is actuated by a piezoelectric ceramic chip. We employ a microelectromechanical system process for the silicon substrate and anodic bonding for assembly of the Pyrex glass and silicon wafer. The reciprocating type micropump contains two nozzle/diffuser elements and a silicon membrane with an embedded piezoelectric ceramic actuator.
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Ni, Jun Hui, Bei Zhi Li, and Jian Guo Yang. "A MEMS-Based PDMS Micropump Utilizing Electromagnetic Actuation and Planar In-Contact Check Valves." Advanced Materials Research 139-141 (October 2010): 1574–77. http://dx.doi.org/10.4028/www.scientific.net/amr.139-141.1574.

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This paper presents a novel low-cost poly(dimethylsiloxane) (PDMS) micropump with simple planar design featuring use of compliant in-contact check valves for reliable operation and easy system integration. The micropump mainly consists of two PDMS functional layers: one through-opening layer incorporating the planar in-contact check valves, pump chamber and flow channels, and the other thin membrane layer covering the chamber with a miniature permanent magnet on top for actuation. A special clamping molding technique was used to fabricate the through-opening functional layer, with which the fl
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Wieczorek, Marcin, Paweł Kościelniak, Paweł Świt, Justyna Paluch, and Joanna Kozak. "Solenoid micropump-based flow system for generalized calibration strategy." Talanta 133 (February 2015): 21–26. http://dx.doi.org/10.1016/j.talanta.2014.04.053.

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6

Parfenovich, S. E., I. K. Khmelnitskiy, V. M. Aivazyan, et al. "Influence of Geometrical Parameters of Hydraulic Drive Based on IPMC Actuator on the Performance of Valveless Membrane Micropump." Nano- i Mikrosistemnaya Tehnika 26, no. 6 (2024): 277–88. https://doi.org/10.17587/nmst.26.277-288.

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The development of microfluidics leads to the need to design high-performance micropumps with minimal overall dimensions. In order to use a valveless membrane micropump in a portable microfluidic system, the influence of the geometric parameters of the hydraulic drive elements based on the IPMC actuator on its performance was studied. The micropump was manufactured with overall dimensions of 24x23x6 mm and with a maximum performance of 3.39 μL/s.
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Leu, Tzong-Shyng, and Ruei-Hung Kao. "Design and operation of a bio-inspired micropump based on blood-sucking mechanism of mosquitoes." Modern Physics Letters B 32, no. 12n13 (2018): 1840027. http://dx.doi.org/10.1142/s0217984918400274.

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The study is to develop a novel bionic micropump, mimicking blood-suck mechanism of mosquitos with a similar efficiency of 36%. The micropump is produced by using micro-electro-mechanical system (MEMS) technology, PDMS (polydimethylsiloxane) to fabricate the microchannel, and an actuator membrane made by Fe-PDMS. It employs an Nd-FeB permanent magnet and PZT to actuate the Fe-PDMS membrane for generating flow rate. A lumped model theory and the Taguchi method are used for numerical simulation of pulsating flow in the micropump. Also focused is to change the size of mosquito mouth for identifyi
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8

Wang, Changhu, and Weiyun Meng. "Research on Simulation Optimization of MEMS Microfluidic Structures at the Microscale." Micromachines 16, no. 6 (2025): 695. https://doi.org/10.3390/mi16060695.

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Microfluidic systems have become a hot topic in Micro-Electro-Mechanical System (MEMS) research, with micropumps serving as a key element due to their role in determining structural and flow dynamics within these systems. This study aims to analyze the influence of different structural obstacles within microfluidics on micropump efficiency and offer guidance for improving microfluidic system designs. In this context, a MEMS-based micropump valve structure was developed, and simulations were conducted to examine the effects of the valve on microfluidic oscillations. The research explored variou
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9

Chen, He, Xiaodan Miao, Hongguang Lu, Shihai Liu, and Zhuoqing Yang. "High-Efficiency 3D-Printed Three-Chamber Electromagnetic Peristaltic Micropump." Micromachines 14, no. 2 (2023): 257. http://dx.doi.org/10.3390/mi14020257.

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This paper describes the design and characteristics of a three-chamber electromagnetic-driven peristaltic micropump based on 3D-printing technology. The micropump is composed of an NdFeB permanent magnet, a polydimethylsiloxane (PDMS) film, a 3D-printing pump body, bolts, electromagnets and a cantilever valve. Through simulation analysis and experiments using a single chamber and three chambers, valved and valveless, as well as different starting modes, the results were optimized. Finally, it is concluded that the performance of the three-chamber valved model is optimal under synchronous start
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10

Liu, Yiqun, Qi Yu, Xiaojin Luo, Le Ye, Li Yang, and Yue Cui. "A Microtube-Based Wearable Closed-Loop Minisystem for Diabetes Management." Research 2022 (October 27, 2022): 1–14. http://dx.doi.org/10.34133/2022/9870637.

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Diabetes is a chronic metabolic disease with a high blood glucose level, leading to both seriously acute and chronic complications. The closed-loop system is an ideal system for diabetes management. However, the large size and high cost of the commercial systems restrict their widespread uses. Here, we present for the first time a microtube-based wearable closed-loop minisystem for diabetes management. The closed-loop minisystem includes a biosensing device, an electroosmotic micropump, and a printed circuit board (PCB) with an algorithm. The microtube-based sensing device coated on the outer
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11

Haldkar, Rakesh Kumar, Vijay Kumar Gupta, Tanuja Sheorey, and Ivan A. Parinov. "Design, Modeling, and Analysis of Piezoelectric-Actuated Device for Blood Sampling." Applied Sciences 11, no. 18 (2021): 8449. http://dx.doi.org/10.3390/app11188449.

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In recent years, micro electro-mechanical system (MEMS)-based biomedical devices have been investigated by various researchers for biomedicine, disease diagnosis, and liquid drug delivery. The micropump based devices are of considerable significance for accurate drug delivery and disease diagnosis. In the present study, design aspects of the piezoelectric actuated micropump used for extraction of blood sample are presented. A pentagonal microneedle, which is an integral part of the micropump, was used to extract the blood volume. The blood was then delivered to the biosensor, located in the pu
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12

Shoji, Eiichi. "Fabrication of a diaphragm micropump system utilizing the ionomer-based polymer actuator." Sensors and Actuators B: Chemical 237 (December 2016): 660–65. http://dx.doi.org/10.1016/j.snb.2016.06.153.

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13

Gallah, Nader, Nizar Habbachi, and Kamel Besbes. "Design and modelling of droplet based microfluidic system enabled by electroosmotic micropump." Microsystem Technologies 23, no. 12 (2017): 5781–87. http://dx.doi.org/10.1007/s00542-017-3414-9.

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14

Rodrigues, Eunice R. G. O., Rui A. S. Lapa, and José L. F. C. Lima. "A Multicommutated Flow System Based on an Opened‐Loop with Micropump Propulsion." Analytical Letters 40, no. 8 (2007): 1632–45. http://dx.doi.org/10.1080/00032710701380517.

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15

Wang, Ping, Zilin Chen, and Hsueh-Chia Chang. "An integrated micropump and electrospray emitter system based on porous silica monoliths." ELECTROPHORESIS 27, no. 20 (2006): 3964–70. http://dx.doi.org/10.1002/elps.200600120.

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16

Attiguppe, Ajay Prabhakar, Dhiman Chatterjee, and Amitava DasGupta. "A Novel Integrated Transdermal Drug Delivery System with Micropump and Microneedle Made from Polymers." Micromachines 14, no. 1 (2022): 71. http://dx.doi.org/10.3390/mi14010071.

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Transdermal drug delivery (TDD), which enables targeted delivery with microdosing possibilities, has seen much progress in the past few years. This allows medical professionals to create bespoke treatment regimens and improve drug adherence through real-time monitoring. TDD also increases the effectiveness of the drugs in much smaller quantities. The use of polymers in the drug delivery field is on the rise owing to their low cost, scalability and ease of manufacture along with drug and bio-compatibility. In this work, we present the design, development and characterization of a polymer-based
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17

Lee, Jae-Won, Seoung Min Back, Tae-Won Kim, and Hyuk Choi. "Development of a microfluidic system with a bearing micropump for applying fluid shear force in an intervertebral disc degeneration model involving mechanical stimulation." Organoid 4 (October 25, 2024): e10. http://dx.doi.org/10.51335/organoid.2024.4.e10.

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Background: The intervertebral disc (IVD) functions as a shock absorber with viscoelastic tissues, including the gelatinous nucleus pulposus and the collagenous annulus fibrosus (AF). External mechanical loading influences IVD homeostasis but can cause damage and inflammatory reactions, contributing to disc degeneration. There is a lack of in vitro platforms for modeling IVD disease with mechanical stimulation.Methods: This study aimed to create a mechanical stimulation-based model by subjecting AF cells to shear stress using a micropump system. A micropump platform was used to measure pulsati
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18

Verma, P., D. Chatterjee, and T. Nagarajan. "Design and development of a modular valveless micropump on a printed circuit board for integrated electronic cooling." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 223, no. 4 (2009): 953–63. http://dx.doi.org/10.1243/09544062jmes1315.

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With constraints on size, cost, reliability, and performance for liquid-based cooling systems, the design of modular micropumps suitable for an integrated thermal management system still remains a challenge. In this paper, the effectiveness of a low-cost valveless micropump—heat exchanger on a printed circuit board is investigated for electronic cooling. Signal conditioning and control electronics are integrated with the fluidic components on the substrate to form a compact modular unit. Piezoelectric actuation and conical diffusers are utilized to generate pulsating flow through a minichannel
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19

Li, Kai, Xianxin Zhou, Haoyuan Zheng, et al. "Achieving Full Forward Flow of Valveless Piezoelectric Micropump Used for Micro Analysis System." Actuators 11, no. 8 (2022): 218. http://dx.doi.org/10.3390/act11080218.

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The valveless piezoelectric micropump has the advantages of simple structure, high precision and low cost, which can realize the directional transport of micro-fluid and wildly be applied in a micro analysis system. However, backflow at the outlet cannot be avoided due to the limitation of its working mechanism. Large reflux rate can increase the volume control accuracy per cycle, but reduces the stability of the micro analysis system. In order to achieve a full forward flow, which reduce the influence of backflow on the system’s stability, the reflux characteristics of the designed valveless
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20

Voigt, P., G. Schrag, and G. Wachutka. "Electrofluidic full-system modelling of a flap valve micropump based on Kirchhoffian network theory." Sensors and Actuators A: Physical 66, no. 1-3 (1998): 9–14. http://dx.doi.org/10.1016/s0924-4247(97)01783-4.

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21

Nguyen, N. T., S. Schubert, S. Richter, and W. Dötzel. "Hybrid-assembled micro dosing system using silicon-based micropump/ valve and mass flow sensor." Sensors and Actuators A: Physical 69, no. 1 (1998): 85–91. http://dx.doi.org/10.1016/s0924-4247(98)00039-9.

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Axelsson, Kristjan, Mohammadhossien Sheikhsarraf, Christoph Kutter, and Martin Richter. "Self-Sensing of Piezoelectric Micropumps: Gas Bubble Detection by Artificial Intelligence Methods on Limited Embedded Systems." Sensors 25, no. 12 (2025): 3784. https://doi.org/10.3390/s25123784.

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Gas bubbles are one of the main disturbances encountered when dispensing drugs of microliter volumes using portable miniaturized systems based on piezoelectric diaphragm micropumps. The presence of a gas bubble in the pump chamber leads to the inaccurate administration of the required dose due to its impact on the flowrate. This is particularly important for highly concentrated drugs such as insulin. Different types of sensors are used to detect gas bubbles: inline on the fluidic channels or inside the pump chamber itself. These solutions increase the complexity, size, and cost of the microdos
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23

Hansen, Thomas Steen, Keld West, Ole Hassager, and Niels B. Larsen. "An all-polymer micropump based on the conductive polymer poly (3,4-ethylenedioxythiophene) and a polyurethane channel system." Journal of Micromechanics and Microengineering 17, no. 5 (2007): 860–66. http://dx.doi.org/10.1088/0960-1317/17/5/003.

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GUAN, Y., Z. XU, J. DAI, and Z. FANG. "The use of a micropump based on capillary and evaporation effects in a microfluidic flow injection chemiluminescence system." Talanta 68, no. 4 (2006): 1384–89. http://dx.doi.org/10.1016/j.talanta.2005.08.021.

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Liu, Guojun, Xuhao Yang, Yan Li, Zhigang Yang, Wen Hong, and JianFang Liu. "Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System." Advances in Materials Science and Engineering 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/160819.

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To prepare the gold nanoparticles (AuNPs) with uniform sizes, fine morphology, and good monodispersity, a pulsed mixing microfluidic system based on PZT actuation was presented. The system includes PZT micropump and Y type micromixer. By adjusting voltage (entrance flow rate), pulsed frequency, phase, and other parameters, a variety of mixing modes can be achieved, so as to realize the controllable synthesis of nanoparticles in a certain range. By numerical simulation and analysis, the channel section size, entrance angle, and pulse frequency were optimized. Based on the optimized structure an
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26

Kudryashova, T. A., S. V. Polyakov, and E. V. Shilnikov. "Simulation of the Knudsen Pump by means of Quasi Gasdynamic Equation System." Journal of Physics: Conference Series 2701, no. 1 (2024): 012053. http://dx.doi.org/10.1088/1742-6596/2701/1/012053.

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Abstract The use of miniature micropumps based on the effect of thermal gas sliding along the walls with an applied temperature gradient (Knudsen pump) is very relevant when creating modern miniature devices. Currently, algorithmically complex methods such as DSMC are usually used to simulate gas flows in such pumps. Progress in the development of algorithms based on a quasi-gasdynamic system of equations, pushed the authors to apply such algorithm to modeling the flow of a binary gas mixture gases in one variant of a micropump. The equations of the QGD system are conservation laws with additi
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Hassan, Rubayet, Sevki Cesmeci, Mahmoud Baniasadi, Anthony Palacio, and Austin Robbins. "A Magnetorheological Duckbill Valve Micropump for Drug Delivery Applications." Micromachines 13, no. 5 (2022): 723. http://dx.doi.org/10.3390/mi13050723.

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In this study, we propose a duckbill valve microfluidic pump that relies on an electromagnetic actuation mechanism. An FEA/CFD-based approach was adopted for the design of the device due to the coupled electromagnetic–solid–fluid interactions in the device. The simulation methodology was confirmed with the previously published data in the literature to ensure the accuracy of the simulations. The proposed optimum duckbill valve micropump can pump 2.45 µL of fluid during the first 1 s, including both contraction and expansion phases, almost 16.67% more than the basic model. In addition, the mode
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28

Bußmann, Agnes, Henry Leistner, Doris Zhou, et al. "Piezoelectric Silicon Micropump for Drug Delivery Applications." Applied Sciences 11, no. 17 (2021): 8008. http://dx.doi.org/10.3390/app11178008.

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Subcutaneous injection is crucial for the treatment of many diseases. Especially for regular or continuous injections, automated dosing is beneficial. However, existing devices are large, uncomfortable, visible under clothing, or interfere with physical activity. Thus, the development of small, energy efficient and reliable patch pumps or implantable systems is necessary and research on microelectromechanical system (MEMS) based drug delivery devices has gained increasing interest. However, the requirements of medical applications are challenging and especially the dosing precision and reliabi
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Nishikata, Kotaro, Masataka Nakamura, Yuto Arai, and Nobuyuki Futai. "An Integrated Pulsation-Free, Backflow-Free Micropump Using the Analog Waveform-Driven Braille Actuator." Micromachines 13, no. 2 (2022): 294. http://dx.doi.org/10.3390/mi13020294.

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The widespread adoption of long-term organs-on-a-chip culture necessitates both active perfusions that mimic physiological flow conditions and minimization of the complexity of microfluidic system and fluid handling. In particular, flow in microtissue such as microvascular is free of pulsation and backflow. The refreshable Braille actuator-based integrated microfluidic system can be employed with simple microchannels and setups. However, due to high pulsatile flow and backflow, ordinary Braille-driven micropumps generate non-physiological flow conditions. We have described a simple method for
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Su, Y., H. Wang, and W. Chen. "Microactuator based on electroplated permanent magnets and flexible polydimethyl siloxane diaphragm." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 222, no. 3 (2008): 517–24. http://dx.doi.org/10.1243/09544062jmes596.

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The design, fabrication, and testing of a novel bidirectional magnetic microactuator were presented in the paper. The microactuator is composed of an integrated planar coil and a flexible polydimethyl siloxane (PDMS) diaphragm with embedded CoNiMnP-based permanent magnet arrays. There is a 7 × 7 array of magnets in a unit. The PDMS diaphragm is 2 mm × mm × 40 μm and the magnet post is 50 × 50 × 20 μm. Computer simulation was applied to verify the geometrical parameters. Electroplating under external magnetic field is carried out to improve the magnetic properties of the electroplated magnet, i
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31

Veeresha, R. K., Muralidhara, Rathnamala Rao, and Astron Manoj Tauro. "Investigation on the Performance of Valveless Pump for Microdelivery of the Fluid, Fabricated Using Tool-Based Micromachining Setup." Journal of Advanced Manufacturing Systems 16, no. 02 (2017): 145–56. http://dx.doi.org/10.1142/s0219686717500093.

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Micropump is an integrated part of microfluidic system and is a boon to the field of miniaturization, owing to its helping hand in numerous applications mainly in biomedical, electronic cooling, fuel cells, spacecraft, etc. In this paper, an attempt is made to design and fabricate valveless pump, with active and passive valves. The actuation element used is piezowafer, piezowafer was experimentally tested and compared with simulated values from ANSYS for its peak displacement and these displacements were used to find volume pumped by pump. The pumping volumes found by experimentation are in go
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Andersen, Truls, Bert Scheeren, Wouter Peters, and Huilin Chen. "A UAV-based active AirCore system for measurements of greenhouse gases." Atmospheric Measurement Techniques 11, no. 5 (2018): 2683–99. http://dx.doi.org/10.5194/amt-11-2683-2018.

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Abstract. We developed and field-tested an unmanned aerial vehicle (UAV)-based active AirCore for atmospheric mole fraction measurements of CO2, CH4, and CO. The system applies an alternative way of using the AirCore technique invented by NOAA. As opposed to the conventional concept of passively sampling air using the atmospheric pressure gradient during descent, the active AirCore collects atmospheric air samples using a pump to pull the air through the tube during flight, which opens up the possibility to spatially sample atmospheric air. The active AirCore system used for this study weighs
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Doms, Marco, and Jörg Müller. "Design, Fabrication, and Characterization of a Micro Vapor-Jet Vacuum Pump." Journal of Fluids Engineering 129, no. 10 (2007): 1339–45. http://dx.doi.org/10.1115/1.2776968.

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A microelectromechanical system (MEMS) vapor-jet pump for vacuum generation in miniaturized analytical systems, e.g., micro-mass-spectrometers (Wapelhorst, E., Hauschild, J., and Mueller, J., 2005, “A Fully Integrated Micro Mass Spectrometer,” in Fifth Workshop on Harsh-Environment Mass Spectrometry;Hauschild, J., Wapelhorst, E., and Mueller, J., 2005, “A Fully Integrated Plasma Electron Source for Micro Mass Spectrometers,” in Ninth International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS), pp. 476–478), is presented. A high velocity nitrogen or water vapor jet i
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Wang, C. T., T. S. Leu, and J. M. Sun. "Unsteady Analysis of Microvalves With No Moving Parts." Journal of Mechanics 23, no. 1 (2007): 9–14. http://dx.doi.org/10.1017/s1727719100001027.

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AbstractNo-moving-parts valves (NMPV) pumps produce the net volume flow due to the difference of pressure resistances between forward and reverse flow of a microchannel structure. NMPV has been developed by a number of research groups. However, most of NMPV in these studies are designed and based on steady state flow conditions. Little data is available regarding the NMPV in unsteady flow conditions. In this study, the performances of NMPV under both steady and unsteady flow conditions are investigated numerically. The NMPV used in this study is a diffuser-type microchannel with diffuser angle
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Nasibullayev, I. Sh. "Reducing the systematic error of the average fluid flow rate in axisymmetric computer model of piezoelectric micropump." Multiphase Systems. 16, no. 1 (2021): 22–33. http://dx.doi.org/10.21662/mfs2021.1.004.

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Mathematical and computer models of an axisymmetric coupled problem of interaction of a fluid and an elastic body for the solving partial differential equations by the finite element method FreeFem ++ software are proposed. In these models, periodic vibrations of annular piezoelectric actuators placed on an elastic tube of circular cross-section lead to radial deformations of the tube. With a synchronous oscillation of the system of piezoelectric actuators, the average fluid flow rate is zero. An asymmetric oscillation pattern (micropump mode) results in a nonzero average flow rate. Two types
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Mohamed, Youssef, and Christopher L. Passaglia. "A portable feedback-controlled pump for monitoring eye outflow facility in conscious rats." PLOS ONE 18, no. 1 (2023): e0280332. http://dx.doi.org/10.1371/journal.pone.0280332.

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Intraocular pressure (IOP) is heavily influenced by the resistance of trabecular outflow pathways through which most of the aqueous humor produced by the eye continuously drains. The standard method of quantifying outflow resistance and other aspects of ocular fluid dynamics is eye cannulation, which allows for direct measurement and manipulation of IOP and flow in animal models. Since the method is invasive, indirect techniques that are slower and less accurate must be used for chronological studies. A novel technology is introduced that can autonomously measure outflow facility in conscious
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Guo, Gang, Xuanye Wu, Demeng Liu, et al. "A Self-Regulated Microfluidic Device with Thermal Bubble Micropumps." Micromachines 13, no. 10 (2022): 1620. http://dx.doi.org/10.3390/mi13101620.

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Currently, many microchips must rely on an external force (such as syringe pump, electro-hydrodynamic pump, and peristaltic pump, etc.) to control the solution in the microchannels, which probably adds manual operating errors, affects the accuracy of fluid manipulation, and enlarges the noise of signal. In addition, the reasonable integration of micropump and microchip remain the stumbling block for the commercialization of microfluidic technique. To solve those two problems, we designed and fabricated a thermal bubble micropump based on MEMS (micro-electro-mechanical systems) technique. Many
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Darintsev, O. V. "Synthesis of new microfluidics models in the research in the “Robotics and Control in Technical Systems” laboratory." Multiphase Systems 17, no. 1-2 (2022): 74–96. http://dx.doi.org/10.21662/mfs2022.1.007.

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Robotics is an interdisciplinary scientific direction, therefore, when solving a number of problems, it becomes necessary to conduct research that is typical for other areas of science. So, when synthesizing new types of equipment in the „Robotics and Control in Technical Systems” laboratory, more accurate characteristics of individual components and assemblies were required, which ultimately led to a whole cycle of work on microfluidics. Of particular interest in the work performed is the development of new microdevices, since this involves the construction of a single complex of new mathemat
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Sha, Wei, Yi Li, Jie Liang, Lei Zhang, and Jianhua Zhang. "P‐10.10: Wearable Transdermal Drug Delivery Devices based on Piezoelectric Micropumps Integrated with Microneedles Array." SID Symposium Digest of Technical Papers 55, S1 (2024): 1271–75. http://dx.doi.org/10.1002/sdtp.17338.

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Transdermal drug delivery refers to a drug delivery route that delivers drugs through the skin to produce local or systemic therapeutic effects. In this work, we propose a parallel valveless piezoelectric micropump integrated with hollow microneedle array, which can be used in flexible wearable transdermal drug delivery systems. The device consists of two valveless piezoelectric micropump, a hollow microneedle array and an electrical control module. The main structure of micropump and the hollow microneedle array are fabricated using 3D printing technology. The valveless piezoelectric micropum
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Mamanee, W., A. Tuantranont, N. V. Afzulpurkar, N. Porntheerapat, S. Rahong, and A. Wisitsoraat. "PDMS Based Thermopnuematic Peristaltic Micropump for Microfluidic Systems." Journal of Physics: Conference Series 34 (April 1, 2006): 564–69. http://dx.doi.org/10.1088/1742-6596/34/1/093.

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Cesmeci, Sevki, Rubayet Hassan, and Mahmoud Baniasadi. "A Comparative Evaluation of Magnetorheological Micropump Designs." Micromachines 13, no. 5 (2022): 764. http://dx.doi.org/10.3390/mi13050764.

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In this study, we assessed the performance characteristics of five different magnetorheological micropump designs, two of which were our proposed designs, while others were from the existing designs in the literature. Comparisons have been performed based on physics-based simulations, and the fully coupled magneto-solid-fluid interaction simulations were carried out in COMSOL Multiphysics software. For a fair and meaningful comparison, both the material and geometric properties were kept the same, and the simulations were run for one complete pumping cycle. The results showed that the proposed
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42

Chen, Xiao-Ming, Yong-Jiang Li, Dan Han, et al. "A Capillary-Evaporation Micropump for Real-Time Sweat Rate Monitoring with an Electrochemical Sensor." Micromachines 10, no. 7 (2019): 457. http://dx.doi.org/10.3390/mi10070457.

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Sweat collection and real time monitoring of sweat rate play essential roles in physiology monitoring and assessment of an athlete’s performance during exercise. In this paper, we report a micropump for sweat simulant collection based on the capillary–evaporation effect. An electrochemical sensor is integrated into the micropump, which monitors the flow rate in real-time by detecting the current using three electrodes. The evaporation rate from micropore array, equivalent to the sweat rate, was theoretically and numerically investigated. The designed micropump yields the maximum collection rat
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Wu, Di, Bing Shi, Bin Li, and Wenming Wu. "A Novel Self-Activated Mechanism for Stable Liquid Transportation Capable of Continuous-Flow and Real-time Microfluidic PCRs." Micromachines 10, no. 6 (2019): 350. http://dx.doi.org/10.3390/mi10060350.

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The self-activated micropump capable of velocity-stable transport for both single-phased plug and double-phased droplet through long flow distance inside 3D microchannel is one dream of microfluidic scientists. While several types of passive micropumps have been developed based on different actuation mechanisms, until today, it is still one bottleneck to realize such a satisfied self-activated micropump for the stable delivery of both single and double-phased liquid inside long microchannel (e.g., several meters), due to the lack of innovative mechanism in previous methods. To solve this probl
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Fournier, S., and E. Chappel. "Modeling of a Piezoelectric MEMS Micropump Dedicated to Insulin Delivery and Experimental Validation Using Integrated Pressure Sensors: Application to Partial Occlusion Management." Journal of Sensors 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/3719853.

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A numerical model based on equivalent electrical networks has been built to simulate the dynamic behavior of a positive-displacement MEMS micropump dedicated to insulin delivery. This device comprises a reservoir in direct communication with the inlet check valve, a pumping membrane actuated by a piezo actuator, two integrated piezoresistive pressure sensors, an anti-free-flow check valve at the outlet, and finally a fluidic pathway up to the patient cannula. The pressure profiles delivered by the sensors are continuously analyzed during the therapy in order to detect failures like occlusion.
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Nasibullayev, I. Sh, and O. V. Darintsev. "Two-dimensional dynamic model of the interaction of a fluid and a piezoelectric bending actuator in a plane channel." Multiphase Systems 14, no. 4 (2019): 220–32. http://dx.doi.org/10.21662/mfs2019.4.029.

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The paper proposes a two-dimensional computer model of the fluid flow in a plane channel under the action of an applied pressure drop with a flat ceramic piezoelectric actuator immersed in it, bending in the transverse direction in proportion to the applied electric voltage. A mathematical model of the coupled liquid-piezodrive system in variational form for numerical simulation by the finite element method is proposed. Since the assignment of the Dirichlet boundary conditions for displacement in this problem, is difficult, an equivalent piezo actuator deformation scheme using the Neumann boun
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Zhou, Xuyan, Meng Gao, and Lin Gui. "A Liquid-Metal Based Spiral Magnetohydrodynamic Micropump." Micromachines 8, no. 12 (2017): 365. http://dx.doi.org/10.3390/mi8120365.

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Hong, Yiying, Misael Diaz, Ubaldo M. Córdova-Figueroa, and Ayusman Sen. "Light-Driven Titanium-Dioxide-Based Reversible Microfireworks and Micromotor/Micropump Systems." Advanced Functional Materials 20, no. 10 (2010): 1568–76. http://dx.doi.org/10.1002/adfm.201000063.

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Farah, Javaid, and M. El-Sheik Said. "FUZZY SIMULATION OF DRUG DELIVERY SYSTEM THROUGH VALVE-LESS MICROPUMP." PJEST 1, no. 1 (2021): 9. https://doi.org/10.5281/zenodo.4774030.

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PJEST journal is a peer-reviewed, open access journal dedicated to publishing high quality research papers, short communication articles and reviews. The multidisciplinary aspects of the journal encourage global collaboration between researchers in multiple fields and provide cross-disciplinary dissemination of findings. The journal publishes original and unpublished research articles, case studies, and state of the art papers. It seeks original research efforts based on theoretical, experimental and simulated work that fills the gap in current knowledge. The annual volume consists of two issu
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UEDA, Yuki, Kenta SHINHA, Shin KOMIYAMA, and Hiroshi KIMURA. "Improvement of Perfusion Functions of the Stirrer-Based Micropump for Microphysiological Systems." Proceedings of the Conference on Information, Intelligence and Precision Equipment : IIP 2023 (2023): IIPA—3–2. http://dx.doi.org/10.1299/jsmeiip.2023.iipa-3-2.

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Jumril Yunas, Muzalifah Mohd Said, Roer Eka Pawinanto, et al. "Magnetic Polymer Based Micropumps for Microfluidic Sample Delivery System." Journal of Advanced Research in Fluid Mechanics and Thermal Sciences 85, no. 1 (2021): 12–21. http://dx.doi.org/10.37934/arfmts.85.1.1221.

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In this paper we present the development of electromagnetic (EM) microfluidic pumps incorporating the magnetic polymer composite for the transport of microfluidic bio-sample. The pump system includes the electromagnetic field generator, a flexible actuator membrane made of polymer material with embedded magnetic particles and valve-less microfluidic channel and chamber. The micropump is fabricated using a MEMS process with additional bonding process. Various types of the magnetic membrane as well as electromagnetic coils were fabricated and characterized to find optimum pump performance. As th
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