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Artykuły w czasopismach na temat "Methamphetamine"

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Kenney, MD, Connor, Julie Rizzo, Elsa Coates, Maria Serio-Melvin, James Aden, Kevin Foster, Kareem AbdelFattah, Tam Pham i Jose Salinas. "701 Impact of Alcohol and Methamphetamine Use on Burn Resuscitation". Journal of Burn Care & Research 44, Supplement_2 (1.05.2023): S126—S127. http://dx.doi.org/10.1093/jbcr/irad045.176.

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Abstract Introduction Mortality associated with burn injuries is declining with improved critical care, including resuscitation. However, patients admitted with concurrent substance use have increased risk of complications and poor outcomes. The impact of alcohol and methamphetamine use on acute burn resuscitation has been described in single center studies, however, has not been studied since implementation of computerized decision support for resuscitation. The purpose of this study was to evaluate resuscitation volumes for patients with alcohol and methamphetamine use within a large prospective observational trial at 5 major US burn centers. Methods We performed an observational trial across five institutions with > 20% total body surface area (TBSA) burn, weighing >40kg that were resuscitated utilizing computerized decision support. Patients were evaluated based presence of alcohol, with a minimum blood alcohol level of 0.10, or positive methamphetamines on urine drug screen. Fluid volumes and urine output were examined over 48 hours and Wilcoxon Method was utilized to compare patient groups. Results A total of 296 patients were analyzed. 37 (12.5%) were positive for methamphetamine use, 50 (16.9%) were positive for alcohol use, and 209 (70.1%) with negative for both. Patients positive for methamphetamine received a mean of 5.30 ±2.63 cc/kg/TBSA, patients positive for alcohol received a mean of 5.41 ± 2.49 cc/kg/TBSA, and patients with neither received a mean 4.33 ± 1.79 cc/kg/TBSA. Patients with methamphetamine or alcohol use had significantly higher fluid requirements than those who were negative for both substances. In the first 6 hours patients with alcohol use had significantly higher urinary output in comparison to patients with methamphetamine use which had similar output to patients negative for both substances. Conclusions This study demonstrated that patients with alcohol and methamphetamine use had statistically significantly larger fluid resuscitation requirements compared to patients without. The effects of alcohol as a diuretic align with previous literature. However, patients with methamphetamine lack the increased urinary output as a cause for their increased fluid requirements. Methamphetamine’s neurologic and cardiovascular effects due to increased release of dopamine, serotonin, and norepinephrine are known. Further investigation is required to better understand the mechanism underlying the need for increased resuscitation after burn injury in patients positive for methamphetamines. Applicability of Research to Practice The impact of alcohol and illicit substances on burn care, especially during the initial resuscitation, aids providers in guiding early critical care.
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Faucett, Erynne A., Katherine M. Marsh, Kayven Farshad, Audrey B. Erman i Alexander G. Chiu. "Maxillary Sinus Manifestations of Methamphetamine Abuse". Allergy & Rhinology 6, nr 1 (styczeń 2015): ar.2015.6.0106. http://dx.doi.org/10.2500/ar.2015.6.0106.

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Methamphetamines are the second most commonly used illicit drug worldwide and cost the United States health-care system ~$23.4 billion annually. Use of this drug affects multiple organ systems and causes a variety of clinical manifestations. Although there are commonly known sequelae of methamphetamine abuse such as “meth mouth,” there is limited evidence regarding maxillary sinus manifestations. The following cases highlight the initial evaluation and management of two methamphetamine abusers with loculated purulent collections within the maxillary sinus as a result of methamphetamine abuse. Our aim was to delineate the otolaryngologic symptoms associated with the patients' methamphetamine abuse. Computed tomography and magnetic resonance imaging studies revealed loculated purulent collections within the maxillary sinus of probable odontogenic origin in both patients. Methamphetamine abuse leading to rampant caries and poor oral hygiene may predispose individuals for craniofacial infections and fluid collections. These cases illustrate the development of maxillary sinusitis and maxilla mucoceles that have been associated with methamphetamine use.
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I, Younes, Elkattawy S, Noori M i Posimreddy S. "Methamphetamine Induced Cardiomyopathy". Journal of Health Care and Research 1, nr 2 (2.06.2020): 78–82. http://dx.doi.org/10.36502/2020/hcr.6165.

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Unfortunately, 35 million people worldwide suffer from drug use disorder while only one in seven people receive treatment. The health impacts combined with the socioeconomic burden of drug abuse are too numerous to count. It is well known that all organ systems are adversely affected by drug use including but not limited to the cardiovascular, respiratory, neurological, and renal. We will focus our attention on the effects of Methamphetamines on the cardiovascular system. Methamphetamines are known to be highly addictive stimulants with significant cardiovascular implications. We have gathered information from the literature available on methamphetamine-associated cardiomyopathy (MACM) and will discuss a case of a 58-year-old male, with no past medical history, who presented with dyspnea secondary to MACM.
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Hendrix, Joshua A., i Cindy Brooks Dollar. "American Slaughterhouses and the Need for Speed: An Examination of the Meatpacking-Methamphetamine Hypothesis". Organization & Environment 31, nr 2 (1.03.2017): 133–51. http://dx.doi.org/10.1177/1086026617697038.

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In Fast Food Nation, Eric Schlosser argues that slaughterhouse workers use methamphetamines to manage the harsh physical and emotional demands of the meatpacking industry. Similar ideas have been raised elsewhere; however, empirical tests of this hypothesis are in short supply. In this article, we elaborate on theoretical mechanisms that may explain why the meatpacking industry encourages methamphetamine use and provide a macro-level test of the meatpacking–methamphetamine hypothesis using 11 years (2001-2012) of hospital admission data and information from annual livestock slaughter reports. Decomposition modeling is used to examine variations across states and within states over time. Results show only modest support for the hypothesis. Specifically, a combined measure of meat is positively and statistically significantly associated with methamphetamine use both within and across states. However, the relationships are not consistently positive or statistically significant across all types of meat. In other words, the meatpacking–methamphetamine relationship is varying and complex.
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Agustin, Michael, Gabriel David, Ji Yeong Kang i Ornusa Teerasukjinda. "Spontaneous Pneumomediastinum and Diffuse Subcutaneous Emphysema after Methamphetamine Inhalation". Case Reports in Pulmonology 2020 (7.03.2020): 1–3. http://dx.doi.org/10.1155/2020/7538748.

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Methamphetamines are commonly abused drugs for their stimulant and euphoric effects. Inhaled and intravenous use may cause damage to the respiratory system. Spontaneous pneumomediastinum is a condition where changes in intrathoracic pressure leads to alveolar rupture and dissection of air along the tracheobronchial tree. Massive subcutaneous emphysema may result from pneumomediastinum which may compromise the central airway. In this case report, we present an unusual case of spontaneous pneumomediastinum and severe subcutaneous emphysema following inhalation of methamphetamine. This case emphasizes the rising concern on the acute respiratory complications of methamphetamine use.
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Khosravi, Navid, Anahita Babaei, Hanieh Azizi i Hamidreza Samaee. "Vasculitis, Thrombotic Thrombocytopenic Purpura, and Disseminated Intravascular Coagulation Associated With Methamphetamine Intoxication: A Case Report". International Journal of Medical Toxicology and Forensic Medicine 11, nr 4 (3.01.2022): 32864. http://dx.doi.org/10.32598/ijmtfm.v11i4.32864.

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Amphetamines and methamphetamines are two groups of substance whose use are increasing globally. Methamphetamines poisoning may develop different sympathetic symptoms; however, developing some complications, such as vasculitis, central nervous system involvement, and kidney injury. In this study, we report a case of methamphetamine poisoning that presented with loss of consciousness and developed Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and pulmonary pseud vasculitis
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Zhao, Yuan-Ling, Wei Zhao, Ming Liu, Lian Liu i Yun Wang. "TBHQ-Overview of Multiple Mechanisms against Oxidative Stress for Attenuating Methamphetamine-Induced Neurotoxicity". Oxidative Medicine and Cellular Longevity 2020 (27.11.2020): 1–10. http://dx.doi.org/10.1155/2020/8874304.

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Methamphetamine is a derivative of amphetamines, a highly addictive central stimulant with multiple systemic toxicity including the brain, heart, liver, lung, and spleen. It has adverse effects such as apoptosis and breakdown of the blood-brain barrier. Methamphetamine is a fatal and toxic chemical substance, and its lethal mechanism has been widely studied in recent years. The possible mechanism is that methamphetamine can cause cardiotoxicity and neurotoxicity mainly by inducing oxidative stress so as to generate heat, eliminate people’s hunger and thirst, and maintain a state of excitement so that people can continue to exercise. According to many research, there is no doubt that methamphetamine triggers neurotoxicity by inducing reactive oxygen species (ROS) production and redox imbalance. This review summarized the mechanisms of methamphetamine-induced neurotoxicity including apoptosis and blood-brain barrier breakdown through oxidative stress and analyzed several possible antioxidative mechanisms of tert-butylhydroquinone (TBHQ) which is a kind of food additive with antioxidative effects. As a nuclear factor E2-related factor 2 (Nrf2) agonist, TBHQ may inhibit neurotoxicity caused by oxidative stress through the following three mechanisms: the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system, the astrocytes activation, and the glutathione pathway. The mechanism about methamphetamine’s toxic effects and its antioxidative therapeutic drugs would become a research hotspot in this field and has very important research significance.
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Edwards, Alexandra Marie, Eric Gregory Johnson i Andrew C. Bernard. "Intraoperative vasopressor use during emergency surgery on injured meth users". Trauma Surgery & Acute Care Open 5, nr 1 (listopad 2020): e000553. http://dx.doi.org/10.1136/tsaco-2020-000553.

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BackgroundMethamphetamine is a growing drug of abuse in America. Patients with recent methamphetamine use pose potential complications to general anesthesia due to changes in hemodynamics and arrhythmias. Limited data exists on the incidence of intraoperative complications on methamphetamine-intoxicated patients requiring urgent or emergent trauma surgery. This study aims to describe intraoperative complications observed in methamphetamine and amphetamine-intoxicated patients requiring emergent surgery.MethodsUsing the Trauma Registry at our ACS-verified level I trauma center, we completed a single-center, descriptive, retrospective cohort review between July 1, 2012 and June 30, 2016, of adult patients requiring emergent surgery with a positive urine-drug screen for methamphetamines or amphetamines. The objective was to evaluate vasopressor utilization during surgical operation.ResultsA total of 92 patients were identified with a positive UDS for amphetamine and/or methamphetamine who went to the operating room within 24 hours of admission. Thirty-two (34%) patients received one or more (≥1) doses of vasopressor, while 60 patients (66%) received no vasopressor. Changes in mean arterial pressure (MAP) were noted in 64%, while only 3% experienced an EKG change. A binomial logistic regression showed age, base deficit and change in MAP to be predictive of vasopressor use (p<0.002). No intraoperative cardiac events or anesthetic complications were seen.DiscussionHemodynamic instability in the amphetamine and methamphetamine-intoxicated population may be more directly related to degree of resuscitation required, than the presence of a positive UDS.Level of evidenceIV
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Safdari, Keyvan M., Curtis Converse, Fanglong Dong, Nickolas Alan MacDougall, Kevin Hyer, Alec Runyon, Haley Ahlering i Mark E. Comunale. "Hemodynamic Effects of Methamphetamine and General Anesthesia". Anesthesiology Research and Practice 2022 (17.02.2022): 1–8. http://dx.doi.org/10.1155/2022/7542311.

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Study Objective. In our practice, we deal with a significant number of patients who require general anesthesia for elective or semielective surgeries and are positive for illicit methamphetamine. We sought to examine our clinical impression that these patients become hemodynamically unstable under general anesthesia. Design. A retrospective analysis of all anesthetic records at our institution over a two-year period was performed. Setting. Operating room cases under balanced anesthesia. Patients. All patients with ASA class I or II, who did not have trauma or were initially admitted to ICU, aged 18–65, without preexisting cardiac, renal, or pulmonary disease. Patients were divided into three groups: those acutely positive for methamphetamine within 48 hours of surgery (n = 137), those positive for methamphetamine between 48 hours and 7 days of surgery (n = 69), and randomly selected controls who were negative for methamphetamine within 7 days of surgery (n = 159). Measurements. Intraoperative hemodynamic instability was defined as either a drop of more than 40% in MAP for greater than 5 minutes or requirement for significant amount of vasopressors. Main Results. Among the patients who were acutely positive for methamphetamine within 24 hours, 31.4% met the criteria for hemodynamic instability within the first hour of general anesthesia, compared to 26.1% of the subacutely positive patients and 6.3% of controls ( p < 0.0001 ). This was despite lower doses of anesthetic medications in the acutely and subacutely positive groups. Conclusion. Patients who present to the operating room with a positive urine drug screen for amphetamines within 2 days of surgery are at increased risk of hemodynamic instability. Postponing surgery up to 7 days somewhat decreases this risk, but not to the levels of patients who do not use methamphetamines.
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Rogers, Jeffrey M., Jennifer E. Iudicello, Maria Cecilia G. Marcondes, Erin E. Morgan, Mariana Cherner, Ronald J. Ellis, Scott L. Letendre, Robert K. Heaton i Igor Grant. "The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition". Viruses 15, nr 3 (3.03.2023): 674. http://dx.doi.org/10.3390/v15030674.

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Objective: Methamphetamine and cannabis are two widely used substances among people living with HIV (PLWH). Whereas methamphetamine use has been found to worsen HIV-associated neurocognitive impairment, the effects of combined cannabis and methamphetamine use disorder on neurocognition in PLWH are not understood. In the present study, we aimed to determine the influence of these substance use disorders on neurocognition in PLWH and to explore if methamphetamine-cannabis effects interacted with HIV status. Method and Participants: After completing a comprehensive neurobehavioral assessment, PLWH (n = 472) were stratified by lifetime methamphetamine (M−/M+) and cannabis (C−/C+) DSM-IV abuse/dependence disorder into four groups: M−C− (n = 187), M−C+ (n = 68), M+C−, (n = 82), and M+C+ (n = 135). Group differences in global and domain neurocognitive performances and impairment were examined using multiple linear and logistic regression, respectively, while holding constant other covariates that were associated with study groups and/or cognition. Data from participants without HIV (n = 423) were added, and mixed-effect models were used to examine possible interactions between HIV and substance use disorders on neurocognition. Results: Compared with M+C+, M+C− performed worse on measures of executive functions, learning, memory, and working memory and were more likely to be classified as impaired in those domains. M−C− performed better than M+C+ on measures of learning and memory but worse than M−C+ on measures of executive functions, learning, memory, and working memory. Detectable plasma HIV RNA and nadir CD4 < 200 were associated with lower overall neurocognitive performance, and these effects were greater for M+C+ compared with M−C−. Conclusions: In PLWH, lifetime methamphetamine use disorder and both current and legacy markers of HIV disease severity are associated with worse neurocognitive outcomes. There was no evidence of an HIV × M+ interaction across groups, but neurocognition was most impacted by HIV among those with polysubstance use disorder (M+C+). Better performance by C+ groups is consistent with findings from preclinical studies that cannabis use may protect against methamphetamine’s deleterious effects.
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Rozprawy doktorskie na temat "Methamphetamine"

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Weber, Lloyd E. "The illicit methamphetamine landscape of Franklin County, Missouri application and analysis of a GIS-based risk assessment model /". Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4513.

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Thesis (M.A.)--University of Missouri-Columbia, 2006.
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on April 21, 2009.) Includes bibliographical references.
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Chen, Chih-Ken. "Predisposing factors to methamphetamine psychosis". Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274936.

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Cotton, Sarah May. "Executive functioning in methamphetamine psychosis". Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/8714.

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Includes bibliographical references.
An association between methamphetamine dependence and neurocognitive impairment has long been established. However, there are a number of research gaps. First, while evidence suggests that the primary cognitive domains affected in methamphetamine dependence are executive functions; previous research fails to employ a comprehensive battery of executive functioning tests. Second, there is little research investigating the specific neuropsychological impairments associated with methamphetamine psychosis in particular. Third, ADHD is highly co-morbid with substance dependence. Symptoms of ADHD were therefore investigated as possible confounders in this study. Fourth, few studies of methamphetamine dependence have explored relationships between neuropsychological data and cortical thickness data; the current study therefore investigated this further. The current study employed a neuropsychological test battery to compare executive functioning across three groups; a methamphetamine dependent group without psychosis (n = 20), a methamphetamine dependent group with psychosis (n =19) and a healthy control group (n = 20); demographically matched. Brain images were acquired using a Siemens Magnetom Allegra 3T system with a high-resolution, T1-weighted, 3D-multiecho MPRAGE sequence with the following scan parameters: TR=2530ms; graded TE=1.53, 3.21, 4.89, 6.57ms; flip angle=7°; FOV=256mm; slice thickness=1mm; 160 slices; and acquisition duration of 10.49 min. Cortical thickness was assessed employing a surface-based cortical reconstruction and automatic labelling tool in the FreeSurfer software package. Four executive domains were identified and evaluated, namely decision making and impulsivity; inhibitory control and setshifting; attention and working memory; and verbal fluency. One-way ANOVAs were conducted in order to assess differences between groups. Analyses indicated significant between group differences on most tasks of executive functioning. Overall the methamphetamine psychosis (MA+) group performed more poorly than the methamphetamine non-psychosis (MA-) group and the controls (NC). Statistically significant between-group differences were observed on inhibitory control and set-shifting (p < .001), attention and working memory (p = .006), and on tasks of generativity (p < .001). Spearman's correlational analyses revealed that in general, executive impairment was associated with cortical thinning of frontal regions in the MA+ group and cortical thickening of frontal regions in the MA- group. This may be reflective of a compensatory response to methamphetamine toxicity in the MA- group. In conclusion, executive functioning was significantly impaired in the MA- group and even more so in the MA+ group. Symptoms of ADHD were not found to be significantly correlated with executive functioning data. Therefore executive dysfunction is more likely the result of MA toxicity than a pre-existing ADHD disorder. An improved understanding of the neuropsychology and neuroanatomy of methamphetamine dependence may ultimately contribute to the clinical management of these individuals.
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Halpin, Laura E. "The Contribution of Ammonia to Methamphetamine Neurotoxicity". University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1370868834.

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Herring, Nicole Reneé. "Effects of Methamphetamine in the Adult Rat". University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1187007484.

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Herring, Nicole Renee. "Effects of Methamphetamine in the Adult Rat". Cincinnati, Ohio : University of Cincinnati, 2007. http://rave.ohiolink.edu/etdc//view?acc_num=ucin1187007484.

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Thesis (Ph.D.)--University of Cincinnati, 2007.
Advisor: Dr. Michael T. Williams PhD (Committee Chair), Charles V. Vorhees PhD, Ton J. Degrauw MD, PhD, Kim B. Seroogy PhD, Gary A. Gudelsky PhD. Title from electronic thesis title page (viewed Mar. 28, 2009). Keywords: Methamphetamine; Path Integration; Spatial Navigation; Corticosterone; Adrenalectomy. Includes abstract. Includes bibliographical references.
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Lapworth, Kely Narelle. "An Investigation of Aggression in Methamphetamine Users". Thesis, Griffith University, 2011. http://hdl.handle.net/10072/366564.

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Methamphetamine (MA) use is associated with increased aggression, though the specific mechanisms through which this association operates remain unclear. Research has demonstrated an association between MA, heightened impulsivity and reduced behavioural control. Similarly, there is strong evidence of a link between MA use and psychotic symptoms. Despite research efforts examining these independent associations, there is a paucity of studies examining how these factors interact to influence the relationship between MA use and aggression. Study 1 was conducted to examine the independent and combined roles of impulsivity and positive psychotic symptoms on the relationship between MA and aggression. In this study, 237 injecting MA users completed a range of self-report measures of hostility, impulsivity, and dependence. Higher levels of MA dependence were associated with increased hostility, higher levels of impulsivity and greater positive psychotic symptoms. Furthermore, the relationship between MA use and aggression was mediated by both impulsivity and positive symptoms of psychosis. Synergistic effects of impulsivity and positive psychotic symptoms on hostility were also observed, with substantially higher levels of hostility being associated with the presence of positive symptoms in conjunction with heightened impulsivity. The results of Study 1 are important in increasing our current understanding of the relationship between MA dependence and aggression, but the reliance on self-report measures does present a problem because of the susceptibility of such measures to report biases. Study 2 was therefore designed to extend previous research by exploring the relationship between MA and aggression using a behavioural measure of aggression, as well as self-report measures. Behavioural and self-report measures of impulsivity were also included. Results revealed that MA users, compared with non-MA users, not only reported higher levels of aggression, but they actually behaved more aggressively when competing with a (fictitious) opponent. Furthermore, some evidence of a dose-response relationship between MA and aggression was apparent. Unexpectedly, no group differences were evident on either the behavioural or self-report measures of impulsivity. Taken together, the present research attests to the robustness of the relationship between MA use and aggression, and points to the need for increased understanding of the complex and multifaceted nature of factors such as impulsivity and positive psychotic symptoms that contribute to this relationship.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Psychology
Griffith Health
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Kennedy, Kelsey Marie. "The Relapse Cycles of Female Methamphetamine Users". Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/579257.

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Methamphetamine use, especially in rural populations, has vast implications on the community and the individuals that comprise it. It has been found that men and women display diverse methamphetamine habits as well as varied effectiveness in treatment. Due to the higher intake and drug-seeking behavior of female methamphetamine users, this qualitative study focused on the relapse and quitting cycles of women in rural Wyoming. Through analysis of forty five semi-structured interviews, it was found that the five major themes of relationships, health, treatment, Department of Corrections, and lifestyle were the most prevalent indicators of becoming clean or relapsing for female methamphetamine users. Furthermore, it was found that women who were pregnant or who had moved away from their home displayed extensive periods of staying clean. By targeting triggers and understanding the reasons behind chronic quitting behaviors, a more comprehensive and individualized treatment plan can be implemented for women struggling with methamphetamine addiction.
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Weeden, Christy Samantha Star. "Neuroprotective Potential of Methamphetamine: Behavioral and Histological Analysis". Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/weeden/WeedenC0507.pdf.

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Stroke is a leading cause of death and ischemic stroke is the most common form. The deficits that follow ischemic stroke include memory and learning impairment. There are presently no treatments that can combat the effects of ischemia after the attack has occurred. Immediately following insult, locomotor activity increases in rodent models. The goal of the current research is to determine if methamphetamine administration following ischemic attack will have neuroprotective effects and prevent changes in locomotor behavior that are observed following insult. Ischemic insult was induced in gerbils by clamping the carotid arteries for 5 mins. Subjects in the sham surgical condition underwent similar surgical procedures, but the carotids were not clamped. Then, subjects were assigned randomly to saline or methamphetamine (5 mg/kg) injection groups. Drug treatment was administered within 2 mins of surgery. Measures of distance traveled, average speed, and number of line crossings were evaluated. Differences in levels of locomotion during the first and second halves of testing were also evaluated. Finally, sections containing the hippocampal CA1 region were rated on a 4-point scale for level of damage. Results show that subjects in the ischemic and saline condition traveled significantly further than those in the sham conditions and ischemic and methamphetamine condition. The speed of ischemic subjects treated with saline was significantly higher than ischemic subjects that received methamphetamine and sham conditions. Also, subjects in the ischemic and saline treatment group crossed more lines than sham and ischemic animals treated with methamphetamine. Analysis of cresyl violet-stained brain sections of ischemic animals treated with saline were rated as having less neuronal cell bodies in the CA 1 region. Ischemic and methamphetamine treated subjects' sections were similar to sham and saline treatment sections. These results suggest that methamphetamine, when injected after transient ischemic attack, may provide neuroprotection from damage that occurs to the CA1 region and prevent the impairments in locomotor behavior.
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Lowther, Courtney. "The Acute, Chronic, and Teratological Effects of Methamphetamine on Aggressive Behaviour in Adolescent Hooded Rats". Thesis, University of Canterbury. Psychology, 2012. http://hdl.handle.net/10092/7044.

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Methamphetamine is a widely abused psychostimulant often associated with aggressive, violent, and criminal behaviour. Research into the effects of adolescent methamphetamine use on aggressive behaviour is limited. This study aimed to establish whether methamphetamine would induce aggressive behaviour following an acute dosing regimen and a chronic dosing regimen. It also aimed to establish a teratological or delayed effect on adult behaviour. To investigate this 20 male and 20 female adolescent rats were equally divided into treatment and control conditions. The treatment condition received a single dose of methamphetamine (2mg/kg) on postnatal day (PND) 35 followed by twice daily doses of methamphetamine (2mg/kg) from PND 36-46. This was done via intraperitoneal injection. The control condition received comparable doses of saline. Animals were tested using the resident intruder test following the single dose, after the completion of the final dose, and again in early adulthood (PND 90). Results found an acute dosing regimen significantly reduced aggressive-like behaviour. A chronic dosing regimen increased aggressive-like behaviour however, this relationship was less clear. Finally, the results found increased aggressive behaviour in adult animals following methamphetamine use in adolescence. This provides preliminary evidence for a teratological effect and support for the neuronal imprinting theory.
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Książki na temat "Methamphetamine"

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Marcovitz, Hal. Methamphetamine. San Diego, Calif: Lucent Books, 2005.

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Prah, Pamela M. Methamphetamine. 2455 Teller Road, Thousand Oaks California 91320 United States: CQ Press, 2005. http://dx.doi.org/10.4135/cqresrre20050715.

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Ambrose, Marylou. Investigate methamphetamine. Berkeley Heights, NJ: Enslow Publishers, Inc., 2015.

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United States. Drug Enforcement Administration, red. Methamphetamine databases. [Washington, D.C.]: U.S. Dept. of Justice, Drug Enforcement Administration, 1997.

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Adamec, Christine A. Amphetamines and methamphetamine. Redaktor Triggle D. J. New York, NY: Chelsea House, 2011.

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U, Hill William, Pagel Thomas J, Wyoming. Office of the Attorney General. i Wyoming. Division of Criminal Investigation., red. Wyoming's methamphetamine initiative. [Cheyenne, Wyo: Office of the Attorney General, 1998.

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New York (State). Temporary Commission of Investigation. Methamphetamine use & manufacture. New York, NY: New York State Commission of Investigation, 2005.

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Division, Wyoming Substance Abuse. Methamphetamine planning study. Cheyenne, WY: Wyoming Dept. of Health, Substance Abuse Division, 2005.

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Office, Illinois Attorney General's. Methamphetamine: Meth, ice, crank. Springfield, Ill.]: Lisa Madigan, Illinois Attorney General, 2003.

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United States. Office of National Drug Control Policy. Methamphetamine: Addiction and treatment. S.l: CreateSpace, 2014.

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Części książek na temat "Methamphetamine"

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Morgan, Michael M., MacDonald J. Christie, Thomas Steckler, Ben J. Harrison, Christos Pantelis, Christof Baltes, Thomas Mueggler i in. "Methamphetamine". W Encyclopedia of Psychopharmacology, 757. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1827.

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Weisheit, Ralph A. "Methamphetamine". W The Handbook of Drugs and Society, 109–27. Hoboken, NJ: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118726761.ch6.

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Dwoskin, Linda P., Paul E. A. Glaser i Michael T. Bardo. "Methamphetamine". W Addiction Medicine, 1049–61. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0338-9_52.

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Jones, Jacob, i Dan Fass. "Methamphetamine Use". W Encyclopedia of Adolescence, 1731–36. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-1695-2_239.

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Draus, Paul J. "Crystal Methamphetamine". W Encyclopedia of Women’s Health, 337–39. Boston, MA: Springer US, 2004. http://dx.doi.org/10.1007/978-0-306-48113-0_113.

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Freye, Enno. "Crystal Methamphetamine". W Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs, 125–29. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2448-0_19.

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Wilson, John Fawcett. "Methylamphetamine (Methamphetamine)". W The Immunoassay Kit Directory, 1659–62. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0679-5_57.

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Jones, Jacob. "Methamphetamine Use". W Encyclopedia of Adolescence, 2331–39. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-33228-4_239.

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Jones, Jacob. "Methamphetamine Use". W Encyclopedia of Adolescence, 1–9. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32132-5_239-2.

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Shukla, Rashi K. "An Introduction to Darkness". W Methamphetamine. University of California Press, 2016. http://dx.doi.org/10.1525/california/9780520291010.003.0001.

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Chapter 1, “Introduction to Darkness,” introduces the focus of this book. An overview of the methamphetamine problem and why it is important is presented. This chapter also describes the materials within each chapter that follows.
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Streszczenia konferencji na temat "Methamphetamine"

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Ma, Baomiao, Kai Yue, Junqiao Xing, Qin Ru, Lin Chen, Yongping Gan, Daisong Wang, Guozhang Jin i Chaoying Li. "A rat model of methamphetamine reinstatement behavior induced by methamphetamine-priming". W International conference on Human Health and Medical Engineering. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/hhme130181.

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DiRienzo, R., R. Wade i J. Reynolds. "164. Methamphetamine and Beyond". W AIHce 2006. AIHA, 2006. http://dx.doi.org/10.3320/1.2758875.

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Mifflin, Amy J., Eddie Hill, Dave Searle i Scott Scheffler. "Methamphetamine: A Blight on Society". W SPE International Conference on Health, Safety, and Environment in Oil and Gas Exploration and Production. Society of Petroleum Engineers, 2008. http://dx.doi.org/10.2118/111949-ms.

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Pulivarthi, V. S., S. S. Vulasala i R. Herrera. "Management of Methamphetamine Induced Pneumonitis". W American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1403.

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Yang, J., E. Lin, C. Rodriguez, S. Lombardi, S. Wu, T. Fernandes, D. S. Poch, D. G. Papamatheakis i N. H. Kim. "Active Methamphetamine Use Worsens Pulmonary Hypertension in Patients with Methamphetamine-associated Pulmonary Arterial Hypertension". W American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3529.

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Xiong, Yijun, Junfeng Gao i Jiaqi Zhang. "Detection methamphetamine patients using ERP features". W 2019 6th International Conference on Information Science and Control Engineering (ICISCE). IEEE, 2019. http://dx.doi.org/10.1109/icisce48695.2019.00059.

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Kennis, B., A. Ali, D. A. Sweeney, D. Lasoff i G. Wardi. "Methamphetamine and Procalcitonin: An Unrecognized Confounder?" W American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2903.

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Coghlan, M. A., B. Ulrich i L. Hinkle. "Methamphetamine Overdose Induced Disseminated Intravascular Coagulation". W American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1566.

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Oppegard, L. J., J. C. Robinson i G. Devendra. "Case Series: Marked Attenuation of Methamphetamine-associated Pulmonary Arterial Hypertension With Methamphetamine Cessation and Pharmacologic Therapy". W American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6117.

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Dokuzparmak, Emre, i Lynn Dennany. "Electrochemiluminescence Detection of Methamphetamine in Biological Matrices". W Counterterrorism, Crime Fighting, Forensics, and Surveillance Technologies IV, redaktorzy Henri Bouma, Robert J. Stokes, Yitzhak Yitzhaky i Radhakrishna Prabhu. SPIE, 2020. http://dx.doi.org/10.1117/12.2573548.

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Raporty organizacyjne na temat "Methamphetamine"

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Spencer, Merianne, Margaret Warner, Jodi Cisewski, Arialdi Miniño, David Dodds, Janaka Perera i Farida Ahmad. Estimates of Drug Overdose Deaths involving Fentanyl, Methamphetamine, Cocaine, Heroin, and Oxycodone: United States, 2021. National Center for Health Statistics (U.S.), maj 2023. http://dx.doi.org/10.15620/cdc:125504.

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Wahl, Troy. Developing Thyronamine Analog Pharmaceuticals Targeting TAAR1 to Treat Methamphetamine Addiction. Portland State University Library, styczeń 2000. http://dx.doi.org/10.15760/etd.1109.

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Poulsen, David. Preclinical and Clinical Development of Low Dose Methamphetamine for the Treatment of Traumatic Brain Injury. Fort Belvoir, VA: Defense Technical Information Center, kwiecień 2014. http://dx.doi.org/10.21236/ada603132.

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Poulsen, David. Pre-clinical and Clinical Development of Low Dose Methamphetamine for the Treatment of Traumatic Brain Injury. Fort Belvoir, VA: Defense Technical Information Center, grudzień 2014. http://dx.doi.org/10.21236/ada612764.

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Boustati, Boustati. Narcotics Flows Through Eastern Africa: the Changing Role of Tanzania and Mozambique. Institute of Development Studies, marzec 2022. http://dx.doi.org/10.19088/k4d.2022.074.

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In the last few decades, the southern route’s use for drug trafficking gained prominence as increased law enforcement and unrest in the Middle East made the traditional ‘Balkan route’ less viable. This southern route transports drugs, mainly heroin, from its production in Afghanistan to Pakistan or Iran, to eastern Africa – including Tanzania and Mozambique- and consequently to South Africa, after which it is moved to Europe (Aucoin, 2018; Otto & Jernberg, 2020). Notable targets of trafficking via the southern route have been the United Kingdom, Belgium, and the Netherlands (UNDOC, 2015). It is difficult to know for certain the quantities of drugs being trafficked through eastern Africa, but the literature puts it at up to 40 tonnes, with 5 of those staying behind, while the rest is transported overseas (Haysom et al., 2018a, 2018b). Due to various political and economic shifts, methamphetamines produced in Afghanistan recently also began to be trafficked alongside heroin shipments through the southern route, with recent estimates putting it at 50% of drugs being trafficked (Eligh, 2021). Most of the literature agrees that, in recent years, drug trafficking routes in eastern Africa have shifted due to political changes, but there is no evidence to suggest that the amount being trafficked have decreased.
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