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Stevenson, Tracey-Lee. "Methadone maintenance, from a woman's perspective". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ55933.pdf.
Pełny tekst źródłaDoverty, Mark. "Acute pain management in methadone maintenance treatment". Title page, abstract and table of contents only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phd743.pdf.
Pełny tekst źródłaBallantyne, Sue. "Methadone maintenance, myth or miracle? : a review of the Queensland Methadone Program 1995-1999 /". [St. Lucia, Qld.], 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16708.pdf.
Pełny tekst źródłaLee, Yan-tsang Samuel. "A study of the relationship between the perception of entry to treatment by young drug abusers attending the government methadone treatment program and program attendance /". Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2013390X.
Pełny tekst źródłaWong, Yiu-kwong. "The effectiveness of the methadone treatment programme and its implications on the anti-drug policy of the HKSAR Government". Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22032368.
Pełny tekst źródłaWong, Chung Shiu-wah Wendy. "The development of the methadone treatment programme in Hong Kong". Click to view the E-thesis via HKUTO, 1988. http://sunzi.lib.hku.hk/hkuto/record/B31975641.
Pełny tekst źródłaEastgate, Katherine. "Methadone maintenance treatment : what are the implications for mothers?" Thesis, University of Hertfordshire, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421276.
Pełny tekst źródłaWang, David. "Sleep disordered breathing in stable methadone maintenance treatment patients /". Connect to thesis, 2006. http://eprints.unimelb.edu.au/archive/00002992.
Pełny tekst źródłaWong, Chung Shiu-wah Wendy, i 黃鍾兆華. "The development of the methadone treatment programme in Hong Kong". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B31975641.
Pełny tekst źródłaPetitjean, Sylvie. "Methadone maintenance treatment in general practice or in specialized centers". Lengerich Berlin Bremen Miami, Fla. Riga Viernheim Wien Zagreb Pabst Science Publ, 2005. http://d-nb.info/1001501985/04.
Pełny tekst źródłaDuronville, John V. "God, drugs, and hope lived religious experiences in a methadone maintenance clinic /". Diss., Connect to the thesis, 2007. http://hdl.handle.net/10066/994.
Pełny tekst źródłaLai, Wing-kai Winky. "A study of factors affecting the effectiveness of the methadone treatment program". Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22331323.
Pełny tekst źródłaPearson, Courtney. "Personal Perceptions and Experiences of Methadone Maintenance Treatment: A Qualitative Descriptive Research Study". Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/33415.
Pełny tekst źródłaMims, Carla A. "An exploratory study of client preference towards methadone maintenance as compared to methadone detoxification in an outpatient treatment facility". DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 1996. http://digitalcommons.auctr.edu/dissertations/3490.
Pełny tekst źródłaLiu, Enwu. "Factors influencing client retention in methadone maintenance treatment clinics in China". Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1580792601&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Pełny tekst źródłaFresquez, Teresa Lyn. "Effect of Therapeutic Alliance of Clients on Methadone Maintenance Treatment Outcomes". ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3297.
Pełny tekst źródłaPace, Christine A. "Substance use outcomes among pregnant and postpartum women in methadone maintenance treatment". Thesis, Boston University, 2012. https://hdl.handle.net/2144/12552.
Pełny tekst źródłaBackground: Methadone maintenance treatment (MMT) is widely used to treat opioid dependence during pregnancy. Though data suggest pregnant women are more likely to engage in MMT compared to non-pregnant women, few studies have examined the effect of pregnancy on abstinence from illicit substances. In addition, there are scant data on postpartum substance use outcomes despite the importance of the postpartum period in determining whether a woman continues in recovery long-term. Methods: Retrospective study of medical records from pregnant and non-pregnant women who emolled in an MMT program over a five year period. Multivariable generalized estimating equations (GEE) logistic regression was used to examine the effect of pregnancy status (pregnant, postpartum or non-pregnant) on the odds of giving an opiate negative urine drug test, and on the odds of giving a urine that was negative not only for opiates, but also for cocaine and benzodiazepines. Results: Urine drug tests from pregnant and postpartum women had almost three times the odds of being opiate-negative urine compared to those from non-pregnant women (AOR 2.90, 95% CI 1.94, 4.33 for pregnant vs. non-pregnant; AOR 2.78, 95% CI 1.77, 4.38 for postpartum vs. non-pregnant). Drug tests from women who were in a residential program on emollment were more likely to be opiate-negative. Results were similar for urine drug tests that were negative for opiates, cocaine and benzodiazepines. Conclusions: Pregnant women with opioid dependence reduce their use substantially in the context of a comprehensive, multidisciplinary program including MMT, and women who remain in MMT postpartum continue to do well. However, the programming needs of non-pregnant women require more attention. In particular, further research should identify whether enhanced access to residential programs or other treatment modalities could help improve this group's engagementwith recovery.
Grönbladh, Leif. "A National Swedish Methadone Program 1966-1989". Doctoral thesis, Uppsala University, Department of Neuroscience, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4001.
Pełny tekst źródłaMethadone Maintenance treatment of compulsive opioid addiction was started by the study of Dole and Nyswander (1965) and has subsequently been replicated in programs throughout the world. Methadone treatment has become the most effective modality for the treatment of chronic heroin addiction.
In 1966 a Swedish National methadone maintenance program was opened at the Psychiatric Research Center, Ulleråker hospital at Uppsala.
The aim of this thesis was to study the outcome of methadone treatment along various lines:
• An open randomised controlled study comparing the efficacy of methadone treatment and drug free treatment in 34 heroin addicts, 20-24 years of age.
• Before/after comparisons of rehabilitation among 345 heroin addicts admitted during the 23 years when this was a centralised National program.
• Retention in treatment.
Study subjects, methods and treatment goals: Subjects underwent an admission procedure when background data was collected through hospital records, and personal interviews. Therapeutic efforts focused on vocational rehabilitation, i.e. a return to full-time work or studies, hoping to make patients abandon their drug addict’s life-style and make them socially accepted and self-supporting.
Results: Thirty-four heroin addicts with a history of 4-8 years of heroin use were randomly assigned either to methadone treatment (17) or an untreated control group (17). The controls could not apply for methadone treatment until two years later. Outcome after six years observation showed that 81% became free of drug abuse, while the corresponding figure for the controls was only 1/17 (6%). The mean yearly death rate for the controls was 7.2%. Likewise, among the total material of 345 heroin addicts, 70-80% of the patients became engaged in work or studies, a significant increase compared with the situation before treatment (1.7%). The program was an effective reducer of illicit heroin use and criminality among its patients and prevented the occurrence of HIV infection among patients in long-term methadone treatment. The average one-year retention during 1967-1989 was 90% and cumulative retention showed that 29% were still in treatment 10 years after admission.
Conclusion: The present results emphasise the importance of vocational rehabilitation and support in a treatment strategy based on long-term maintenance therapy.
Lin, Chunqing. "Factors associated with successful implementation of the methadone maintenance therapy (MMT) programs in China". Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1723178181&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Pełny tekst źródłaLai, Wing-kai Winky, i 黎榮佳. "A study of factors affecting the effectiveness of the methadone treatment program". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B4389401X.
Pełny tekst źródłaNehring, Sandra Ellen. "An exploratory study of heroin addicts' perceptions of methadone treatment". CSUSB ScholarWorks, 1996. https://scholarworks.lib.csusb.edu/etd-project/1237.
Pełny tekst źródłaDavie-Gray, Alison. "The Early Development and Family Environments of Children Born to Mothers Engaged in Methadone Maintenance During Pregnancy". Thesis, University of Canterbury. Psychology, 2011. http://hdl.handle.net/10092/5508.
Pełny tekst źródłaDell, Erin. "Nurses' attitudes and experiences working with women receiving methadone maintenance therapy in the postnatal period". Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50283.
Pełny tekst źródłaApplied Science, Faculty of
Nursing, School of
Graduate
Zador, Deborah Public Health & Community Medicine Faculty of Medicine UNSW. "Studies in opioid drug related death". Awarded by:University of New South Wales. Public Health & Community Medicine, 2009. http://handle.unsw.edu.au/1959.4/44765.
Pełny tekst źródłaSheerin, Ian G., i n/a. "Consequences of drug use and benefits of methadone maintenance therapy for Maori and non-Maori injecting drug users". University of Otago. Christchurch School of Medicine & Health Sciences, 2005. http://adt.otago.ac.nz./public/adt-NZDU20070502.142602.
Pełny tekst źródłaGibson, Amy Elizabeth National Drug & Alcohol Research Centre Faculty of Medicine UNSW. "Mortality among the recipients of methadone, buprenorphine and naltrexone maintenance for the treatment of opioid dependence: the levels, predictors and causes of mortality". Awarded By:University of New South Wales. National Drug & Alcohol Research Centre, 2009. http://handle.unsw.edu.au/1959.4/44508.
Pełny tekst źródłaLean, Rachel Emma. "The Mental Health Outcomes of Children Born to Methadone Dependent Mothers : The Role of Out-of-Home Care at Age 4.5-Years". Thesis, University of Canterbury. Psychology, 2012. http://hdl.handle.net/10092/6865.
Pełny tekst źródłaKomalasari, Rita. "Key perspectives on Opioid Substitution Treatment (OST) programmes, using Methadone Maintenance Treatment (MMT) programmes in Indonesian prisons as a case study". Thesis, University of Stirling, 2018. http://hdl.handle.net/1893/28543.
Pełny tekst źródłaEvans, Jessica Smith. "Assessing and Comparing Attitudes Toward Addiction and Methadone Treatment". Ohio University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1155845971.
Pełny tekst źródłaBroers, Kayser Barbara. "HIV and hepatitis B and C in a cohort of methadone maintenance clients in Geneva, 1988-1995". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ50728.pdf.
Pełny tekst źródłaMonwell, Bodil. "De sökte substitutionsbehandling-vad skiljde dem åt? : Jämförelse i bakgrundsfaktorer mellan opiat- och opioidberoende utifrån ASI-intervjuer". Thesis, Hälsohögskolan, Högskolan i Jönköping, HHJ, Avd. för beteendevetenskap och socialt arbete, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-19104.
Pełny tekst źródłaPritham, Ursula A. "Pharmacologic Treatment of Opiod Dependency in Pregnancy: Methadone Versus Buprenorphine and Subsequent Neonatal Abstinence Syndrome". Fogler Library, University of Maine, 2009. http://www.library.umaine.edu/theses/pdf/PrithamUA2009.pdf.
Pełny tekst źródłaAronowitz, Shoshana. "Screaming Behind a Door: The Experiences of Individuals Incarcerated Without Opioid Maintenance Treatment". ScholarWorks @ UVM, 2015. http://scholarworks.uvm.edu/graddis/385.
Pełny tekst źródłaElkader, Alexander. "Influencing Factors on Methadone Pharmacology: Impact on Satisfaction with Methadone Maintenance Treatment". Thesis, 2009. http://hdl.handle.net/1807/17756.
Pełny tekst źródłaMorton, Erin Brooke. "The clinical pharmacology of methadone induction". Thesis, 2007. http://hdl.handle.net/2440/41434.
Pełny tekst źródłaThesis (Ph.D.) -- School of Medical Sciences, 2007
Morton, Erin Brooke. "The clinical pharmacology of methadone induction". 2007. http://hdl.handle.net/2440/41434.
Pełny tekst źródłahttp://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1269301
Thesis (Ph.D.) -- School of Medical Sciences, 2007
Stones, George. "Predicting Community-based Methadone Maintenance Treatment (MMT) Outcome". Thesis, 2012. http://hdl.handle.net/1807/34932.
Pełny tekst źródłaChang, Chih-Ting, i 張芝庭. "Factors for Interruption of Methadone Maintenance Treatment Patients". Thesis, 2010. http://ndltd.ncl.edu.tw/handle/84195081417722515523.
Pełny tekst źródła中國醫藥大學
醫務管理學研究所碩士班
98
Research Purpose: According to researches that the maintenance rate is only about 50% after receiving MMT in domestic and foreign drug addicts. MMT curative effect has been proved, but so far few researchers have examined the factors for interruption of MMT cases. Therefore, in this study, we will examine the factors for interruption of Methadone Maintenance Treatment cases especially focusing on the significant differences caused by their individual characteristics, the factors involving them in the MMT project and factors for interruption of MMT project. Research Method: We used a self-administered, structured questionnaire to collect people, with their agreement, who participated in MMT project, and receiving treatment over three months in central Taiwan during 1998 July to December. There were 420 valid questionnaires (valid return rate is 79.8%).After receiving the questionnaire, we’ll check whether they interrupt MMT treatment. Then, we use chi-square test and independent-sample t test to inquire into the influence relationship of each variable. Finally, we use stepwise logistic regression analysis to find the important factors affecting the factors for interruption of MMT project. Research Results: The subjects tend to be male, their average age is 38.4 years old, the marriage status was unmarried, the education level was high school, the month income was under 18,000 dollars, employed, in a habit of smoking, a half of subjects have ever used Amphetamines, the average duration of using heroin is 13.02 years, the average quit drug times is 1.4, the time to MMT treatment is within 30 minutes. Advanced analysis found that age, educational level, changes in Methadone doses and the need of counseling for MMT subjects caused significantly differences for interruption on drug addicts. Conclusion and Suggestion: Overall, educational level and counseling need of drug addicts were the important factors affecting the interruption of MMT project. In order to reduce interruption of drug addiction treatment patients, we recommend that MMT hospitals and government agencies should have supporting measures for their friendship, work and mental need.
Huang, Bo-Hau, i 黃柏豪. "Pharmacogenomics of Methadone in Patients with Maintenance Treatment". Thesis, 2010. http://ndltd.ncl.edu.tw/handle/24391408731359633077.
Pełny tekst źródła中國醫藥大學
藥物安全研究所
98
The most common treatment for opioid dependence is substitution therapy with methadone, and the dosage of methadone is individualized. The aim of the present study is to identify whether the single nucleotide polymorphisms (SNP) or haplotypes in related genes associated with response to methadone maintenance treatment (MMT) and dosage requirement of methadone. After signed the informed consents, approximately 300 subjects were recruited and allocated into three groups according to their stabilized daily dose of methadone: the first group was comprised of subjects stabilized on a lower dose, the second group comprised of subjects stabilized at a medium dose, and the last group comprised of subjects stabilized at a higher dose. The decision to split the groups at a methadone dose was based on the major maintained dose of patients. The control group was healthy volunteers with no lifetime history of heroin dependence. In this study, there are 15 SNPs detected by real-time polymerase chain reaction with 5''-nuclease allele discrimination assays (ABI PRISM 7900 land) and restriction fragment length polymorphism (RFLP) assay in ABCB1, NR1I2, CYP2B6 genes (pharmacokinetics) and in OPRM1, DRD2, ANKK1, GNB3 genes (pharmacodynamics). As results, the maximum daily methadone doses were significantly assoiated with the ABCB1 rs1045642C>T, CYP 2B6 rs3745274G>T, OPRM1 rs1799971A>G, DRD2 rs1799978C>T and rs6275A>G SNPs. Carriers of the variant rs1799971G alleles required higher methadone doses than noncarriers. In addition, the subjects carried the CCGAC haplotype of ANKK1 rs1800497C>T, DRD2 rs4648317C>T, rs1799978 A>G, rs1076560 C>A, rs6275 C>T required significant lower dose than TTGAT haplotype (p<0.0001; OR=0.004; 95% CI=0.001-0.053). Pharmacogenetics has great potential for improving treatment outcome as we identify gene variants and polymorphism is recognized as important determinants of interindividual variability in methadone pharmacokinetics and pharmacodynamics.
Wu, Shiow-Ling, i 吳秀玲. "HCV Influences the Methadone Maintenance Treatment for Addiction". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/99395206054992693437.
Pełny tekst źródła國防醫學院
生命科學研究所
102
Background and Objectives: Heroin-dependent patients typically contract hepatitis C virus (HCV) at a disproportionately high level due to needle exchange. The liver is the primary target organ of HCV infection and also the main organ responsible for drug metabolism. Methadone maintenance treatment (MMT) is a major treatment regimen for opioid dependence. HCV infection may affect methadone metabolism but this has rarely been studied. In our current study, we first established a method to measure the plasma concentrations of methadone and its metabolites under no enantiomer standard circumstances. We then aimed to test the hypothesis that HCV may influence the methadone dosage and its plasma metabolite concentrations in a MMT cohort from Taiwan. Methods: A liquid chromatography-photodiode array (LC-PDA) method using a chiral analytical column was developed to determine the plasma levels of enantiomers of methadone and its chiral metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenyl pyrrolidine (EDDP), without the standard compounds of R-form or S-form enantiomers. This method was established by the characteristics of recombinant cytochrome P-450 (CYP) isozymes; where CYP2C19 prefers to metabolize R-methadone and CYP2B6 prefers to metabolize S-methadone. A total of 366 MMT patients were recruited and measured their plasma methadone and metabolite concentration. The levels of plasma hepatitis B virus (HBV), HCV, human immunodeficiency virus (HIV) antibodies (Ab), liver aspartate aminotransferase (AST) and alanine aminotransferase (ALT), as well as methadone and its metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) were measured along with the urine morphine concentration and amphetamine screening. Results: We incubated the racemic methadone standard with either enzyme for 24 hours. We identified the retention times of R- and S-methadone to be around 10.72 and 14.46 min, respectively. Of the 352 subjects in our cohort with HCV test records, 95% were found to be positive for plasma anti-HCV antibody. The liver functional parameters of AST (Wilcoxon Rank-Sum test, P=0.02) and ALT (Wilcoxon Rank-Sum test, P=0.04), the plasma methadone concentrations (Wilcoxon Rank-Sum test, P=0.043) and the R-enantiomer of methadone concentrations (Wilcoxon Rank-Sum test, P=0.032) were significantly higher in the HCV antibody-positive subjects than in the HCV antibody-negative patients, but not the S-EDDP/ methadone dose ratio. The HCV levels correlated with the methadone dose ( = 14.65 and 14.13; P=0.029 and 0.03) and the S-EDDP/ methadone dose ratio ( = -0.41 and -0.40; P=0.00084 and 0.002) in both univariate and multivariate regression analyses. Conclusions: We conclude that HCV may influence the methadone dose and plasma S-EDDP/ methadone dose ratio in MMT patients in this preliminary study.
MA, JUNG-LI, i 馬榮梨. "The Relationships of Medication Adherence in Methadone Maintenance Therapy". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/q2mz39.
Pełny tekst źródła輔英科技大學
護理系碩士班
104
Background: The adherence problems have often interrupted the treatment of methadone maintenance therapy, causing the relapse of heroin addiction and the increase of medical care expenses. The study probes into the related factors of adherence, expecting to provide a better strategy and reduce the waste of medical and social resources. Purposes: The study discusses the related factors of basic attributes of population, social supports, physical and mental condition, heroin rehabilitation and adherence. Methods: The study designed the self-administered questionnaires by Cross-Sectional and Descriptive study, and the methadone cases of a medical center in southern region were involved. During the research period from September to December in 2015, the addicted cases that had methadone treatment for over a month, accepted the interview and did not involve in deferred prosecution were included. The attendants filled out the questionnaires including basic attributes of population, family care scale, social support scale, anxiety scale, decision of rehabilitation scale, hesitating attitude toward methadone questionnaire, heroin treatment history and chronic disease investigation. The effective response rate reached 96%, and SPSS 19.0 statistical software was used for filing and data analysis. Results: 120 attendants completed the investigation, and most of the cases were in the age of 40-49, male, unmarried and junior high school as the highest education level. The subjects were grouped by the attendance above and under 80%. The related factors that influence the attendance include “gender” (x2=11.98、p=.001), where the female has a lower attendance than male; “use time of methadone” (t=2.214、p=.029): the longer the period of taking the methadone, the better the attendance; “anxiety - autonomic nervous reaction” (t=-2.249、p=.026): the stronger the anxiety reaction of autonomic nervous, the lower the attendance would be. Suggestion and conclusion: In the aspect of the clinic, it is suggested providing female-friendly environment for treatment, consider individual needs and strengthen the screening mechanism of psychical treatment. Introducing the study results in on-the-job education and improving the popularity of referring cases through inter-academic cooperation are both feasible for strategic guidance and future reference. Keywords: Methadone maintenance therapy, Heroin addiction, medication adherence
YING-CHUN, CHOU, i 周盈君. "The Effectiveness of Methadone Maintenance Treatment in Northern Taiwan". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/31031139870843989980.
Pełny tekst źródła國立臺灣師範大學
健康促進與衛生教育學系
100
Objective: This paper examined the costs and the effectiveness before the Methadone Maintenance Treatment (MMT) and after one-year follow-up of MMT from patients’ perspective in four hospitals in northern Taiwan. Methods: The participants in this study were recruited from the population of outpatients with heroin addiction enrolled at methadone maintenance treatment program in four hospitals in northern Taiwan. We adopted costs and effectiveness from patients’ perspective. The WHOQOL-BREF and the employment status were administered at baseline and at one-year follow-up to calculate the incremental quality of life (QoL) gained and the wages differences. The averted incarceration costs were computed by the estimates from government reports or literatures and the criminal records from Ministry of Justice. Results: The implementation of MMT program cost were 37,989, 38,992 and 40,195 NT dollars from 2009 to 2011; however, without the implementation of MMT program, the cost was 672,954. The measurements for benefit were quality of life, employment, and criminal activities. The cost per QoL (Quality of Life) in physical health domain was the highest of four domains (24,214 NT dollars) and the cost per QoL in psychological health domain was the lowest (10,280 NT dollars). The unemployment rate decreased after one-year follow-up; however, the wages per hour slightly decreased. Compared with the year of 2004 to 2007, the intervention of MMT decreased criminal offenses and incarceration costs. Conclusions: During one-year follow-up of MMT, this study has shown that methadone maintenance treatment is cost-effective in terms of quality of life improvement, increased employment and averted incarceration costs.
Changchien, Te-Chang, i 張簡德璋. "Erectile Dysfunction among Male Patients Receiving Methadone Maintenance Therapy". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/19804736913786699097.
Pełny tekst źródła樹德科技大學
人類性學研究所
103
Introduction: Methadone maintenance therapy is an effective treatment for patients of heroin use disorder. However, there are still some stigmatization and preoccupation from Chinese society, especially for those with Human Immunodeficiency Virus (HIV) infection. So we had little information about their sexual function, which could interfere adherence to treatment and quality of life. Because that heroin or even methadone might affect erectile function was hypothesized, we need to explore the actual prevalence and associated factors predicting erectile dysfunction (ED) in Taiwan in order to enhance their sexual right. Methods: A total of 450 men with diagnosis of heroin use disorder in the methadone clinic of E-Da Hospital, Kaohsiung City, Taiwan, were potentially eligible to participate in this study. Of these, 106 patients were recruited (including 13 patients with HIV infection) and were evaluated with International Index of Erectile Function-5 (IIEF-5), Taiwanese Depression Questionnaire (TDQ), Chinese Health Questionnaire (CHQ), Chinese CAGE screen for alcohol misuse, demographic data, HIV infection, risky sexual behaviors and substance use measures. Men who had no any sexual intercourse were excluded. Descriptive (by Chi-square test and T test) and inferential (by Pearson’s correlation and regression models) statistics were performed with SPSS. Results: There was no significant difference for demographic characteristics between the “new patient” group and the treatment group, except of more condom use and less sexual activities immediately after using drug in the treatment group. Similar findings were noted about the difference between HIV infection group and non-HIV group. HIV infection group had more sexual partners with drug use. As to mean scores of IIEF-5, CHQ and TDQ, no significant difference was detected between the “new patient” and the treatment groups. Besides, there was a negative correlation between IIEF-5 and CHQ (r=-0.319; p<0.01); between IIEF-5 and TDQ (r=-0.262; p<0.01). On multivariate regression models, common mental symptoms (CHQ) were associated with lower IIEF-5 (p=0.001), but there were no significant associations between IIEF-5 and age, body mass index (BMI), duration of methadone treatment, methadone dosage, TDQ, risky sexual behaviors, HIV or other illicit drug use. Tendency to have alcohol use problem was significantly associated with higher IIEF-5 (p=0.044). Conclusions: First, to the best of our knowledge, this is the first study, which focused on the ethnic Chinese patients co-morbided with heroin use disorder and HIV infection, to demonstrate associated risk factors of ED in Taiwan. Second, our finding about the prevalence of ED is lower and closer to previous studies in comparison with another three China studies (using IIEF-5 also). That perhaps reflected we indeed excluded nonsexually active patients. Because those patients would be evaluated as having severe ED while scoring IIEF-5. Finally, we need to promote the importance of common mental symptoms (including anxiety symptoms) on erectile dysfunction.
SHIH, MENG-SIOU, i 施孟秀. "The Experiences of Heroin Addicts in Methadone Maintenance Treatment". Thesis, 2019. http://ndltd.ncl.edu.tw/handle/664h4j.
Pełny tekst źródłaMaruyama, Anna. "The Comparison of prescriptions dispensed for methadone maintenance patients to non-methadone maintenance patients for the treatment of chronic diseases using PharmaNet data". Thesis, 2012. http://hdl.handle.net/1828/4056.
Pełny tekst źródłaGraduate
Tsai, Shu-Ho, i 蔡淑合. "Exporing Factors Related Methadone Maintenance Treatment among Injecting Drug Users". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/pn4qd9.
Pełny tekst źródła國立陽明大學
護理學系暨研究所
97
Objectives: The aim of this study was to examine factors related methadone maintenance treatment among injecting drug users in Taiwan. Methods: The Study used a mixed research to collect qualitative and quantitative data. Conceptuial framework base on Andersen’s behavioural model of health care utilization . Structured Questionnaire were conduct with one hundred eighteen injecting drug uses and depth interviews were seventeen participants. Data obtained from the effectiveness investigation harm reduction plan in Taiwan . Results: In the predisposing factors: fear of the police investigation officers, for fear of boss knowing or encountered an acquaintance were obstructive factors; In the enabling factors: quantitative were shows the most goto hospitals period of time and the cost of methadone maintenance treatment was related with different regions; the depth qualitative interviews were mainly found: free charge , drugs friends of effects , improve of health、improve of family relations, economic improvement were facilitated factors ; On the contrary , convenience of location services, the continuity of medication, the cost is too expensive were obstructive factors. In the need factors, qualitative finding : the experience of the failure of drug use are facilitated factors., and the period in the ring , they still use of heroin were barrier factors.; the research common finding the quality of personal life to improve the economic. Conclusion: Andersen model’s predisposing factors, enabling factors and needs factors have playing important roles in injecting drug users to regular use methadone maintenance treatment for improved of health status, family and economics.
Chen, I.-Chun, i 陳逸群. "Alcohol Use Problem among Patients in Methadone Maintenance Treatment Program". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/55375671862737905259.
Pełny tekst źródła國立臺灣大學
預防醫學研究所
97
OBJECTIVE: To examine the prevalence rate and predictors of alcohol use problem, as well as predictors of dropout among patients undergoing methadone maintenance treatment (MMT). Alcohol use problem is defined as two levels separately, level one is excessive and hazardous drinking, level two is alcohol abuse and dependence. METHODS: This is a prospective follow-up study. Study population includes 438 patients retaining more than 6 months in MMT from the Fong-Yuan Hospital and Tau-Yuan Psychiatric Center. Demographic and clinical characteristics were collected for each patient at the beginning, and treatment-related variables were collected during treatment process. Excessive drinking and hazardous drinking, alcohol abuse and dependence were measured by Chinese Version Alcohol Use Disorders Identification Test (Chinese Version AUDIT) and breath alcohol concentration. RESULT: The prevalence rate of excessive drinking and hazardous drinking among MMT patients is 31.4%, and the prevalence rate of alcohol abuse and dependence is 12.0%. The predictors of excessive and hazardous drinking among MMT patients include attendance rate more than 90%(OR=0.54,95%CI=0.30-0.97), age older than 35 years old(OR=0.48,95%CI=0.27-0.86),and alcohol use at intake(OR=5.30,95%CI=2.87-9.76) is a risk factor. The predictors of dropout among MMT patients include methadone dose less than 60 mg (Wald test p-value<0.001), without governmental fund (Wald test p-value<0.001). CONCLUSION:The high prevalence rate of excessive and hazardous drinking among MMT patients underscores the needful screening and intervention for alcohol use problem .Those patients who are younger and have poor adherence, alcohol use at intake should be screened for excessive and hazardous drinking.
Wu, Mei-Hui, i 吳美惠. "Quality of Life for Heroin Addicts accepting Methadone maintenance treatment". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/29562247497471306833.
Pełny tekst źródła中臺科技大學
健康產業管理研究所
99
With Methadone Maintenance Therapy (MMT), this study aims to discuss the difference in the quality of life (QOL) for heroin addicts so as to draw up a health management project for heroin addicts. With the single time-series design in Quasi-experimental design, the differences in QOL before applying MMT and three and six months after using are compared. With 320 patients who accepted MMT in central Taiwan as the subjects, three interviews were preceded within April – November, 2010. Based on the World Health Organization (WHO) QOL questionnaire– Brief reference for Taiwan (WHOQOL-BREF (TW)), the quality of life was measured. The findings show male (91.56%), female (8.44%), and average age 39.68 years old; the educational background below junior high school 60.00%; unemployed 47.19%; single 45.94%, having fixed abode 94.38%; average age for first use of drugs 24.13 years old; average age for first use of heroin 26.03 years old; having heroin with intravenous injection 80.00%; average use of heroin 3.20 times each day; average expense on heroin 3,910 NT dollars each day; average use of half mace of heroin 5.4 days; sharing needles with others 11.25%, sharing preparation solution injection with others 18.44%; infected with human immune deficiency virus (HIV) 22.81%; suffering from Hepatitis C 85.31%; and having prior convictions on drugs 74.69%. It is concluded that most patients accepting MMT are middle-aged, unemployed male with the educational background of junior high school, having heroin with intravenous injection, and 85% suffering from Hepatitis C. Six months after the heroin addicts accepting MMT, overall and physiological health, psychology, social relations, and environment in QOL presented better than they did before and three months after the therapy. Apparently, continuously accepting MMT could effectively improve the quality of life. The heroin addicts are suggested to patiently and permanently accept MMT to put an end to the use of heroin as well as to promote the quality of life.
Su, Ting-Yu, i 蘇亭羽. "Genetic variation analysis of Methadone Maintenance Treatment for Heroin Addicts". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/8rgpd4.
Pełny tekst źródłaDoverty, Mark. "Acute pain management in methadone maintenance treatment / by Mark Doverty". Thesis, 2001. http://hdl.handle.net/2440/21876.
Pełny tekst źródłaIncludes bibliography.
1 v. (various paging) : ill. ; 30 cm
In the light of a general concensus that in the treatment of pain, patients with a prior history of substance abuse (particulary opioid dependence) appear to be at increased risk for pain mismanagement problems, this thesis aims to produce data that will eventually help in the formulation of prescribing guidelines, improved policies, and help direct optimal acute pain management for methadone maintenance patients.
Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 2002