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1

Roohi, Aysha. "Toxoplasma gondii infection and the host cell metabolism." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648369.

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2

Ren, Bingjian. "Physiological importance of phospholipid biogenesis in Toxoplasma gondii." Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/20721.

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Toxoplasma gondii ist ein obligater intrazellulärer Parasit, der bei Menschen und Nutztieren Toxoplasmose verursacht. Die Phospholipid-Biosynthese ist entscheidend für das erfolgreiche intrazelluläre Überleben und die Replikation des Parasiten, da sie eine wichtige Rolle bei der Biogenese von Membranorganellen, der Signal- transduktion und anderen zellulären Prozessen spielt. Hier untersuchten wir die physiologische Bedeutung von zwei Synthesewegen, die für PtdEtn und PtdIns verantwortlich sind. Wir zeigen das Vorhandensein einer neuartigen PtdIns-Synthase (PIS) in T. gondii, die als Tg
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3

Nitzsche, Richard. "Genetic dissection of the central carbon metabolism in the intracellular parasite Toxoplasma gondii." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2017. http://dx.doi.org/10.18452/17744.

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Toxoplasma gondii ist ein weit verbreiteter einzelliger Parasit, der fast alle warmblütigen Organismen infizieren kann. Asexuelle Fortpflanzung des Parasiten in seiner Wirtszelle wird durch aufeinanderfolgende lytische Zyklen erreicht, was die Bereitstellung einer signifikanten Menge an Energie und Biomasse erforderlich macht. Diese Arbeit zeigt, dass Glukose und Glutamin die beiden wichtigsten physiologischen Nährstoffe für die Synthese von Makromolekülen (ATP, Nukleinsäure, Proteine und Lipide) in T. gondii sind. Die Verfügbarkeit einer der beiden Kohlenstoffquellen reicht aus, um das Überle
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4

Sampels, Vera. "Plasticity of the phosphatidylcholine biogenesis in the obligate intracellular Parasite Toxoplasma gondii." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16491.

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Der obligat intrazelluläre Parasit Toxoplasma gondii ist der Erreger der Toxoplasmose, und dient zugleich als wichtiger Modellorganismus für weitere Human- und Tierpathogene, wie z.B. Plasmodium oder Eimeria. Die Vermehrung von T. gondii erfordert eine effiziente Biosynthese von Phospholipiden für die Herstellung neuer Membranen, was durch die de novo Synthese durch den Parasiten, und/oder den Import von Lipiden aus der umgebenden Wirtszelle gewährleistet werden kann. Während der Parasit zahlreiche Möglichkeiten für Synthese oder Import von PtdEtn und PtdSer verwendet, scheint die Biosynthese
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5

Sundaram, Lalitha Sridevi. "Toxoplasma gondii-mediated host cell transcriptional changes lead to metabolic alterations akin to the Warburg effect." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/267958.

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Toxoplasma gondii is an obligate intracellular parasite, that is able to infect any nucleated cell. An important global pathogen, T. gondii can cycle between primary and secondary hosts, thus enabling widespread penetrance. Within its intracellular niche – a membrane-bound parasitophorous vacuole – T. gondii is nevertheless able to subvert a variety of host cell processes to allow its continued survival and replication. This includes modulation of host signalling processes as well as the scavenging of nutrient macromolecules. In recent years, microRNAs have emerged as important regulators of c
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6

Blume, Martin. "Characterization of the differential significance of sugar Import in the apicomplexan parasites Toxoplasma gondii and Plasmodium." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16396.

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Toxoplasma gondii und Plasmodium Spezies sind obligat intrazelluläre Parasiten, die Zucker zur Energiehomöostase als auch für die Synthese lebenswichtiger Makromoleküle verwenden. Die hier vorgestellten Daten zeigen, dass der Glukosetransporter von T. gondii, TgGT1, und die homologen Transporter von P. falciparum und P. berghei, PfHT1 und PbHT1, neben Glukose auch Mannose, Fructose und Galactose transportieren. Toxoplasma Tachyzoiten exprimieren neben TgGT1 noch einen weiteren putative Zuckertransporter (TgST2) an der Parasitenoberfläche. Beide Proteine sind nicht essentiell, wie durch ihre in
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7

Molan, Aus. "Involvement of Toxoplasma gondii and associated inflammatory markers in the pathogenesis of type 2 diabetes mellitus." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2020. https://ro.ecu.edu.au/theses/2338.

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Type 2 diabetes mellitus (T2DM) continues to be a major challenge for public health authorities worldwide due to its growing prevalence rates. This chronic disorder is characterised by persistent hyperglycaemia with disturbances in fat, carbohydrate, and protein metabolism resulting from abnormalities in insulin secretion, action, or both. While potential causes such as obesity, physical inactivity, and dietary patterns have been proposed to explain the growing epidemic, there may also be additional unidentified novel risk factors, such as subclinical inflammation caused by infectious agents,
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8

Costa, Beatriz Guerreiro Basilio. "Estudo da modulação do metabolismo lipídico de células dendríticas humanas na infecção por Toxoplasma gondii." Instituto Oswaldo Cruz, 2012. https://www.arca.fiocruz.br/handle/icict/7036.

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Submitted by Alessandra Portugal (alessandradf@ioc.fiocruz.br) on 2013-10-03T11:40:07Z No. of bitstreams: 1 Beatriz Guerreiro Basilio Costa.pdf: 1448715 bytes, checksum: 9fad325ac3484b88b47961c78ef5db34 (MD5)<br>Made available in DSpace on 2013-10-03T11:40:07Z (GMT). No. of bitstreams: 1 Beatriz Guerreiro Basilio Costa.pdf: 1448715 bytes, checksum: 9fad325ac3484b88b47961c78ef5db34 (MD5) Previous issue date: 2012<br>Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil<br>A toxoplasmose é uma doença de alta prevalência no mundo, causada pelo Toxoplasma gondii, um parasita
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9

Silva, Camila Luna da. "Estudo do metabolismo mitocondrial e da resposta anti-apoptótica de células endoteliais humanas durante a evolução da infecção por taquizoítos de Toxoplasma gondii." Universidade do Estado do Rio de Janeiro, 2013. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=8172.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A toxoplasmose é uma zoonose amplamente distribuída que afeta mais de um terço da população mundial e de grande importância na saúde pública. A maioria das infecções em humanos por Toxoplasma gondii é assintomática. A toxoplasmose é amplamente investigada visto que se apresenta como uma doença grave em pessoas imunodeprimidas (portadores da síndrome da imunodeficiência adquirida (SIDA), não tratados, indivíduos transplantados, paciente em tratamento quimioterápico ou em uso de drogas supressoras e gestantes). A toxoplasmose congêni
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10

HIRAMOTO, ROBERTO M. "Efeitos da radiacao ionizante sobre a estrutura, metabolismo e infecciosidade de um protozoario patogenico, Toxoplasma gondii (Nicolle and Manceaux, 1908)." reponame:Repositório Institucional do IPEN, 1998. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10660.

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11

Nitzsche, Richard [Verfasser], Nishith [Gutachter] Gupta, Kai [Gutachter] Matuschewski, and Maik [Gutachter] Lehmann. "Genetic dissection of the central carbon metabolism in the intracellular parasite Toxoplasma gondii / Richard Nitzsche ; Gutachter: Nishith Gupta, Kai Matuschewski, Maik Lehmann." Berlin : Lebenswissenschaftliche Fakultät, 2017. http://d-nb.info/1130217469/34.

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12

Mason, Sam. "Toxoplasma gondii in sheep." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556024.

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Toxoplasma gondii infects sheep horizontally (from cat faeces) or vertically (transplacentally). Vertically infected lambs sometimes die. Here, transmission and performance impacts were considered in one Charollais flock and one Swaledale flock. B1-PCR was performed on umbilical cord, heart and brain. MAT was performed on blood and pleural effusion. IgG-ELISA was performed on colostrum. B1-PCR was more sensitive than four other methods, producing a band in 50% of replicates when each replicate contained 0.02 parasite genome copies. 16/243 (6.6%) viable Charollais, 30/263 (11.4%) viable Swaleda
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13

Paugam, André. "Protéasome de "Toxoplasma gondii"." Paris 5, 2002. http://www.theses.fr/2002PA05P611.

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Le protéasome est un complexe protéique cellulaire dont le rôle essentiel est la protéolyse des protéines anormales. Notre objectif était de caractériser le protéasome du toxoplasme (tachyzoi͏̈tes de la souche RH). Par immunoblot, nous avons montré que des extraits cellulaires de toxoplasmes étaient marqués par l'anticorps anti-protéasome MCP231. Par immunofluorescence et microscopie confocale, nous avons observé une localisation essentiellement cytoplasmique du protéasome de T. Gondii, résultat confirmé par la microscopie électronique. L'étude des activités protéolytiques du protéasome a mont
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14

Xia, Dong. "Proteomics of Toxoplasma gondii." Thesis, University of Liverpool, 2009. http://livrepository.liverpool.ac.uk/1276/.

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The Apicomplexan parasite Toxoplasma gondii is an obligate intracellular parasite. Infection by T .gondii causes the disease toxoplasmosis, which is one of the most prevalent parasitic diseases of animals and humans. It has been 100 years since the first discovery of the parasite in 1908; research on T. gondii has been carried out in many scientific disciplines consistently expanding the understanding of this parasite. In the last ten years, the developments of EST, microarray, genome sequencing and continuing efforts towards genome annotation has centralized the focus of T. gondii research on
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15

Roch-Deries, Florance Candolfi Ermanno. "Choriorétinite à toxoplasma gondii." [S.l] : [s.n.], 2003. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2003_ROCH_DERIES_FLORENCE.pdf.

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16

com, Nevi Parameswaran@gmail, and Nivethitha (Nevi) Parameswaran. "Toxoplasma gondii in Australian Marsupials." Murdoch University, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20100203.145857.

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Diagnostic tools were developed and utilised to detect Toxoplasma gondii infection in a range of Australian marsupial species and identify epidemiological trends. An ELISA was developed to detect anti-T. gondii IgG in macropod marsupials. When compared with the commercially available MAT (modified agglutination test), the ELISA was in high agreement and yielded a ê coefficient of 0.96. Of 18 western grey kangaroos (Macropus fuliginosus) tested for the presence of T. gondii DNA by PCR, the 9 ELISA positive kangaroos tested PCR positive and the 9 ELISA negative kangaroos tested PCR negative indi
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17

Kremer, Katrin. "Vesicular trafficking in Toxoplasma gondii." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4753/.

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Toxoplasma gondii is an obligate intracellular protozoan parasite with a worldwide prevalence. Together with the causative agent of malaria (Plasmodium falciparum) and other medically important pathogenic parasites it belongs to the phylum of the Apicomplexa. Besides identifiable eukaryotic organelles, apicomplexan parasites differ from other eukaryotic cells by an extra set of specialised secretory organelles (micronemes, rhoptries and dense granules), that are sequentially secreted during invasion of the host cell. Upon host cell contact the apically located micronemes are the first organell
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18

Bhalla, Mayank. "Molecular studies on Toxoplasma gondii." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339977.

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19

Parameswaran, Nevi. "Toxoplasma gondii in Australian marsupials /." Murdoch University Digital Theses Program, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20100203.145857.

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20

Parameswaran, Nivethitha (Nevi). "Toxoplasma gondii in Australian Marsupials." Thesis, Parameswaran, Nivethitha (Nevi) (2008) Toxoplasma gondii in Australian Marsupials. PhD thesis, Murdoch University, 2008. https://researchrepository.murdoch.edu.au/id/eprint/1680/.

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Diagnostic tools were developed and utilised to detect Toxoplasma gondii infection in a range of Australian marsupial species and identify epidemiological trends. An ELISA was developed to detect anti-T. gondii IgG in macropod marsupials. When compared with the commercially available MAT (modified agglutination test), the ELISA was in high agreement and yielded a ê coefficient of 0.96. Of 18 western grey kangaroos (Macropus fuliginosus) tested for the presence of T. gondii DNA by PCR, the 9 ELISA positive kangaroos tested PCR positive and the 9 ELISA negative kangaroos tested PCR negative indi
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21

Parameswaran, Nivethitha (Nevi). "Toxoplasma gondii in Australian Marsupials." Parameswaran, Nivethitha (Nevi) (2008) Toxoplasma gondii in Australian Marsupials. PhD thesis, Murdoch University, 2008. http://researchrepository.murdoch.edu.au/1680/.

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Diagnostic tools were developed and utilised to detect Toxoplasma gondii infection in a range of Australian marsupial species and identify epidemiological trends. An ELISA was developed to detect anti-T. gondii IgG in macropod marsupials. When compared with the commercially available MAT (modified agglutination test), the ELISA was in high agreement and yielded a ê coefficient of 0.96. Of 18 western grey kangaroos (Macropus fuliginosus) tested for the presence of T. gondii DNA by PCR, the 9 ELISA positive kangaroos tested PCR positive and the 9 ELISA negative kangaroos tested PCR negative indi
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22

Chaichan, Patcharee. "Epidemiology of Toxoplasma gondii in Thailand." Thesis, Limoges, 2017. http://www.theses.fr/2017LIMO0014/document.

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Toxoplasma gondii est un parasite intracellulaire obligatoire. L'infection par T. gondii est largement répandue dans le monde entier. Néanmoins, elle est peu étudiée dans les pays d'Asie du Sud-est dont la Thaïlande.Nous avons réalisé 3 travaux sur le terrain en Thaïlande pour essayer de comprendre la circulation de ce parasite à travers une étude de séroprévalence chez des poulets en zone rurale et des essais d’isolement de souches chez les animaux en vue d’un génotypage. Lors des deux premières missions de terrain dans deux villages de la province de Kanchanaburi, nous avons cherché à déterm
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23

Woods, Stuart. "Immunological control of toxoplasma gondii infection." Thesis, University of Strathclyde, 2012. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=19276.

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Prevalent worldwide, the protozoan parasite, Toxoplasma gondii, is an important cause of spontaneous abortion, ocular disease, mental retardation and encephalitis. Currently there are no human vaccines available. The first major aim of this study was to test potential HLA restricted peptide vaccines, previously shown to be protective in HLA-transgenic mice, against oocyst infection. The ability of entrapment within non-ionic surfactant vesicles to improve the efficacy of the HLA-B*0702 restricted vaccine was also studied. In parallel we tested the novel T. gondii ΔRPS13 live-attenuated vaccine
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24

Cirelli, Kimberly M. "Rodent inflammasome activation by Toxoplasma gondii." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/105635.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Toxoplasma gondii is an obligate intracellular pathogen capable of chronically infecting nearly all warm-blooded animals, including humans. The chronic stage is characterized by the presence of semi-dormant cysts in brain and muscle tissues. These cysts are crucial in the success of Toxoplasma as they are orally infectious and allow for the transmission of the parasite between hosts. As the host immune response drives cyst forma
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25

Ravindran, Sandeep. "Effector protein secretion by toxoplasma gondii /." May be available electronically:, 2009. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Brennan, Anthea. "Toxoplasma gondii infection in Australian felines." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/15060.

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Toxoplasma gondii is a significant human and animal parasite with worldwide occurrence. The population structure and prevalence in definitive hosts and intermediate hosts has been well studied in a number of regions including North and South America and Europe. While Toxoplasma gondii has been previously reported in a number of mammalian species in Australia, there is a surprising lack of information regarding the population structure of T.gondii in Australia and current rates of exposure in domestic companion animal hosts. Members of the felidae family are the only known definitive host of T.
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27

Burrells, Alison Clair. "Toxoplasma gondii in animal and human hosts." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9628.

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The protozoan parasite Toxoplasma gondii (T. gondii) is an important zoonotic pathogen, which has the ability to infect all warm blooded mammals including humans, with approximately one third of the human population predicted to be infected. Transmission of the parasite to the foetus during pregnancy can result in miscarriage, however, a child infected during pregnancy may go on to develop clinical symptoms such as retinochoroiditis (ocular toxoplasmosis), hydrocephalus or learning difficulties in later life. Post-natally acquired infection in humans is generally asymptomatic, however, individ
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Riahi, Dehkordi Hamayoun. "Hammondia hammondi : études comparatives avec Toxoplasma gondii." Limoges, 1997. http://www.theses.fr/1997LIMO105E.

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Liu, Elizabeth. "The Autophagy Pathway and Toxoplasma gondii Infection." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1428103561.

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Bertin, Brigitte. "Etude immunochimique des antigènes de Toxoplasma gondii." Bordeaux 2, 1985. http://www.theses.fr/1985BOR22001.

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Hartmann, Jan. "Golgi and centrosome cycles in Toxoplasma gondii." [S.l. : s.n.], 2005.

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Bertin, Brigitte. "Etude immunochimique des antigènes de Toxoplasma gondii." Grenoble : ANRT, 1985. http://catalogue.bnf.fr/ark:/12148/cb37594507t.

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Jesus, Rogerio Fernando de. "Infeccção natural por Toxoplasma gondii em quirópteros." Universidade Federal da Bahia, 2015. http://repositorio.ufba.br/ri/handle/ri/20375.

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Carey, Robert Francis IV. "Toxoplasma gondii and behavioral modification in hosts." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12065.

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Thesis (M.A.)--Boston University<br>Toxoplasma gondii is a heteroxenous protozoan parasite that is found in nearly every species of mammal and billions of latently infected humans worldwide. The symptoms and morbidities associated with acute, congenital, and AIDS-associated toxoplasmosis are familiar to many, while those associated with latent toxoplasmosis are not nearly as well known. Behavioral manipulation is a common strategy of parasite and parasitoid species, and recent research into T. gondii has revealed that T. gondii infection alters the way rodents respond to the odor of the urine
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Parigi, Maria <1984&gt. "Toxoplasma gondii in animals and the environment." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6423/1/Parigi_Maria_tesi.pdf.

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Toxoplasma gondii is an obligate intracellular parasite capable of infecting virtually all warm-blooded species, including humans, but cats are the only definitive hosts. Humans or animals acquire T. gondii infection by ingesting food or water contaminated with sporulated oocysts or by ingesting tissue cysts containing bradyzoites. Toxoplasmosis has the highest human incidence among zoonotic parasitic diseases, but it is still considered an underreported zoonosis. The importance of T. gondii primary infection in livestock is related to the ability of the parasite to produce tissue cysts in inf
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Parigi, Maria <1984&gt. "Toxoplasma gondii in animals and the environment." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6423/.

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Toxoplasma gondii is an obligate intracellular parasite capable of infecting virtually all warm-blooded species, including humans, but cats are the only definitive hosts. Humans or animals acquire T. gondii infection by ingesting food or water contaminated with sporulated oocysts or by ingesting tissue cysts containing bradyzoites. Toxoplasmosis has the highest human incidence among zoonotic parasitic diseases, but it is still considered an underreported zoonosis. The importance of T. gondii primary infection in livestock is related to the ability of the parasite to produce tissue cysts in inf
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37

Nolan, Kay. "The transmission dynamics of Toxoplasma gondii in sheep." Thesis, University of Warwick, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479313.

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38

Mohammed, Saleem. "Molecular studies on the protozoan parasite Toxoplasma gondii." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262211.

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Wheeler, Ruth Belinda. "Studies of the molecular biology of Toxoplasma gondii." Thesis, University of Reading, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356985.

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40

Nickdel, Mohammad Barat. "Role of Th2 cytokines in Toxoplasma gondii infection." Thesis, University of Strathclyde, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248258.

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Henriquez, Fiona Luisa. "Recharacterization of Toxoplasma gondii dense granule protein GRA3." Thesis, University of Strathclyde, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273437.

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Wansadhipathi-Kannangra, Nilu Kumari. "Sphingolipid synthases of Toxoplasma gondii and other organisms." Thesis, Durham University, 2011. http://etheses.dur.ac.uk/3204/.

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THE SPHINGOLIPID SYNTHASES OF TOXOPLASMA GONDII AND OTHER ORGANISMS Nilu Kumari Wansadhipathi-Kannangara Toxoplasma gondii is an obligate intracellular protozoan parasite of the phylum Apicomplexa, and toxoplasmosis is an important disease in immuno-compromised individuals - especially AIDS patients, organ transplant recipients and patients receiving anti-cancer chemotherapy. Toxoplasmosis also has economic importance as it results in spontaneous abortion in economically important animals. Due to emerging drug resistance and the possible side effects of the existing therapeutics there is a nec
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Ghérardi, Arnaud. "Toxoplasma gondii : étude de la purine nucléoside phosphorylase." Lyon 1, 2001. http://www.theses.fr/2001LYO1T208.

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La 4e de couverture indique : "Toxoplasma gondii est un protozoaire Apicomplexa responsable de toxoplasmose congénitale et cérabrale. Cette dernière est une importante cause de morbidité et de mortalité chez l'immunodéprimé. Comme la majorité des protozoaires, T. Gondii est incapable de synthétiser ses propres purines et dépend donc entièrement de celles de son hôte. Il dispose des enzymes pour interconvertir celles-ci de façon à former les bases puriques qui intégreront divers métabolimes et constitueront les acides nucléiques. Le dosage de six enzymes de la voie des purines a montré que la p
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44

Liew, Lloyd. "Structural studies on microneme proteins from Toxoplasma gondii." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11654.

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Toxoplasma gondii is a polyxenous parasite of the phylum Apicomplexa and the etiological agent of the coccidian disease Toxoplasmosis. Toxoplasma gondii is characterized by its unique gliding motility as well as its ability to infect virtually all nucleated cells. The micronemes are a group of secretory organelles that contribute to the ability of the parasite to recognize the surface of the host-cell prior to parasite invasion via the secretion of adhesive protein complexes. Previous attempts at obtaining structural data for several microneme proteins from Toxoplasma gondii such as microneme
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Bouleau, Anne Pascaline. "Identification et caractérisation de métalloprotéases de Toxoplasma gondii." Thesis, Reims, 2014. http://www.theses.fr/2014REIMM202/document.

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Toxoplasma gondii est un parasite protozoaire intracellulaire obligatoire appartenant à la famille des Apicomplexa. Chez les protozoaires, les protéases possèdent des rôles clés au niveau du cycle parasitaire, et sont ainsi considérées comme des facteurs de virulence. Chez T. gondii, les métallopeptidases pourraient être impliquées dans la traversée des différentes barrières biologiques. A l'heure actuelle, seules cinq métallopeptidases de T. gondii ont été décrites : une aminopeptidase N, deux toxolysines, une leucine aminopeptidase et une FtsH1 peptidase. Lors de l'étude de l'influence de l'
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Alruhaili, M. H. B. "Genetic diversity of African isolates of Toxoplasma gondii." Thesis, University of Salford, 2016. http://usir.salford.ac.uk/37753/.

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Toxoplasma gondii is an intracellular protozoan parasite and has the ability to infect all warm-blooded animals, including humans. While the three clonal lineages of T. gondii (I, II and III) predominate in North America and Europe, strains from other regions in the world appear to have more diverse genotypes. The aim of the current research is to analyse the level of genetic variation among local African T. gondii isolates in relation to their phenotype (genotype phenotype relationships). In this study, multi-locus nested PCR sequence analysis of seven Ugandan T. gondii isolates was applied u
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Frohnecke, Nora. "Funktionelle Charakterisierung des Ferredoxin Redoxsystems von Toxoplasma gondii." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19075.

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Toxoplasmose ist weltweit eine der am häufigsten auftretenden parasitären Zoonosen mit einer geschätzten Infektionsrate von über 30%. Toxoplasma gondii (Phylum: Apicomplexa) besitzt ein Plastid ähnliches Organell, den Apicoplasten. In diesem befindet sich das einzig bekannte Redoxsystem, welches aus der Ferredoxin-NADP+-Reduktase und Ferredoxin (Fd) besteht. Fd als Elektonendonator liefert Elektronen an verschiedene essentielle Stoffwechselwege, wie der Isoprenoidvorstufen- und Liponsäuresynthese. Um die bei einem Elektronentransfer benötigte direkte Protein-Protein-Interaktion eingehend zu an
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Dardé, Marie-Laure. "Contribution à la caractérisation de Toxoplasma Gondii : étude isoenzymatique." Limoges, 1990. http://www.theses.fr/1990LIMO101A.

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Gastens, Martin. "Virulenz-assoziierte Proteine von Toxoplasma gondii Identifikation und funktionelle Charakterisierung /." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968522270.

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Adjogblé, Koku Zikpi. "Biochemische und funktionelle Charakterisierung eines neuen "Dense-granules"- Proteins von Toxoplasma gondii: GRA9." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971753792.

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