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Rozprawy doktorskie na temat „Medical XAI”

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Data publikacji: 6 września 2023

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1

Nilsson, Tilde. "Metodjämförelse mellan Immulite® 2000 XPi och Phadia® 250 för analys av IgE-antikroppar i serum : En studie med avseende på IgE-medierad allergi". Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-71473.

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Allergi förekommer hos cirka 20 % av befolkningen i Sverige. Av de 20 % bedöms 40 % vara allergiska mot pollen. Allergi uppstår då en individ upprepade gånger exponeras för ett allergiframkallande ämne sk allergen. IgE-antikroppar bildas och binder till basofila granulocyter och mastceller. Den allergiska reaktionen eller överkänslighetsreaktionen av typ I uppkommer när ett allergen exempelvis pollen, kommer i direkt kontakt med IgE-antikroppar på mastceller eller basofila granulocyter. Allergiska individer har högre koncentration av IgE-antikroppar i blodet än icke allergiska. Normal koncentration av IgE i serum hos icke allergiker är <0.35 kU/L. Syftet med studien var att genom analys av serumprover från 50 patienter jämföra två immunokemiska metoder på analysinstrumenten, Siemens immulite® 2000 XPi och Thermo Fisher Phadia® 250, för detektion av IgE-antikroppar riktade mot en inhalationspanel respektive björkpollen. Immulite® 2000 XPi användes som referensmetod. Jämförelsen gjordes för att bedöma om metoderna gav överensstämmande resultat och om Phadia® 250 skulle kunna användas som ett alternativ till rutinmetoden. Studiematerialet bestod av 50 patienter i åldrarna 18–80 år, 17  män (34 %) och 33 kvinnor (66 %). Resultatet visade att metoderna överlag gav överrensstämmande resultat med avseende på positiva och negativa IgE-värden, men att de uppmätta värdena för metoderna saknade överrensstämmelse. Analysresultaten från de båda metoderna gav överlag god korrelation vid analys av specifikt IgE mot björk (R=0,977) men en svagare korrelation vid analys av inhalationspanel (R=0,609). Med hjälp av Man-Whitney u-test sågs en signifikant skillnad vid IgE-analys mot björk (p= 0,0006) däremot sågs inte en signifikant skillnad mellan metodernas IgE-värden mot inhalationspanelerna (p=0,2398). För att kunna utvärdera om Phadia® 250 skulle kunna användas som ett alternativ till rutinmetoden, krävs en större population av prover samt fler analystillfällen.
Allergy is nowadays a public health problem that’s affecting 20 % of the Swedish population. A very common allergen that is related to 40% of all the allergic cases is pollen. Allergic reactions occur when an  individual is repeatedly exposed to an allergenic substance called allergene. IgE antibodies then form and bind to basophilic granulocytes and mast cells. The allergic reaction or type I hypersensitivity reaction, occurs when an allergen such as pollen comes into direct contact with IgE antibodies on mast cells or basophilic granulocytes. IgE is produced by plasma cells under the influence of CD4+ T lymphocytes. The IgE antibodies synthesized then sensitize the mast cells and basophilic granulocytes which are the most active cell types involved in allergic reactions. Allergic individuals have a higher concentration of IgE antibodies in the blood than non-allergic. Normal serum IgE concentration in non-allergic patients is <0.35 kU / L. The aim of the study was to compare two immunochemical instruments, Siemens Immulite® 2000 XPi and Thermo Fisher Phadia® 250, by analyzing 50 serum samples to detect possible presence of IgE antibodies directed against an inhalation panel and a single allergen (IgE against birch). The study material consisted of 50 patients between the ages of 18-80, 17 men (34%) and 33 women (66%). The results showed that overall the two methods yielded consistent results due to positive and negative IgE values, but the measured values of the methods lacked concordance. The analysis results from the two methods generally yielded good correlation in the analysis of specific IgE against birch (R = 0.977) but a weaker correlation in the inhalation panel analysis (R = 0.609). Man-Whitney u-test showed a significant difference in IgE analysis against birch (p = 0.0006). However, a significant difference between the IgE values of the methods against the inhalation panels (p = 0.22398) was not observed. To be able to evaluate whether Phadia® 250 could be used as an alternative to the routine method, a larger population of samples and more analytical occasions is required.
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Cubas-Peña, Rebeca. "'Every practitioner his own compiler' : practitioners and the compilation of Middle English medical books, with special reference to York Minster Library, XVI E. 32". Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7222/.

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By analysing the codicology and other features of a group of fifteenth-century medical manuscripts, my thesis aims to shed some light into the unexplored role of the compilers of medical material. These individuals assembled a number of booklets mostly produced in Middle English, and put them together with the intention to create volumes entirely dedicated to medicine. The thesis proposes a typology that will show the existence of a type of medical codices, whose substantial codicological alteration evince the involvement of the medical practitioners and earliest owners of the volumes in their making. I will argue that the manuscripts were gathered, arranged, and sometimes copied by these practitioners, who, in an attempt to create their own medical handbooks, customised their books in a manner they considered to be pertinent and useful for their practice. A comprehensive analysis of York Minster Library, MS XVI E, one of these practitioner-compiled composites (as I have labelled them) will offer new insights into a codex which has never been examined in detail. The study will eventually demonstrate that medical practitioners played a significant role in the production of fifteenth-century English medical books, especially in the compilation and arrangement of the codices’ booklets.
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Lu, Xia [Verfasser], Faikah [Akademischer Betreuer] Güler i Hermann [Akademischer Betreuer] Haller. "Hypoxia induced renal fibrosis is mediated by PKC-[alpha]/[beta] signaling / Xia Lu. Department of Nephrology Hannover Medical School. Betreuer: Faikah Güler ; Hermann Haller". Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2011. http://d-nb.info/1011308223/34.

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Laennec, René Théophile Hyacinthe. "Propositions sur la doctrine d'Hippocrate relativement à la médecine-pratique présentées à l'école de médecine de Paris et soutenues le 22 prairial an XII /". Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1804x241.

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Zhang, Jieneng. "Jin shi liu nian (1989-2005) Xianggang Zhong yao bu liang fan ying shi gu de fen xi yan jiu /". click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b1998697xa.pdf.

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Roux, Philibert-Joseph. "Coup-d'œil physiologique sur les sécrétions présenté et soutenu à l'école de médecine de Paris le 10 germinal an XI /". Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1803x243.

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Hruša, Aljaksandr I. "Kancyljaryja Vjalikaha knjastva Litoŭskaha 40-ch hadoŭ XV - peršaj palovy XVI st". Minsk "Belaruskaja Navuka", 2006. http://bvbr.bib-bvb.de:8991/F?func=service&docl̲ibrary=BVB01&docn̲umber=015414469&linen̲umber=0002&funcc̲ode=DBR̲ECORDS&servicet̲ype=MEDIA.

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Guerbois, Denis François Noël. "Essai sur la nostalgie, appelée vulgairement maladie du pays présenté et soutenu à l'école de médecine de Paris le 29 prairial an XI /". Paris : BIUM, 2004. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1803x290.

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Petit, Édouard. "Essai sur l'influence de quelques affections morales dans les maladies chirurgicales des armées présenté et soutenu à l'école de médecine de Paris le 9 ventose an XI /". Paris : BIUM, 2004. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1803x203.

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Désortiaux, P. "Des signes de l'infanticide et des moyens de la constater dissertation médico-légale présentée et soutenue à l'Ecole de médecine de Paris le 24 messidor an XI /". Paris : BIUM, 2004. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1803x313.

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Lima, Gabriela Rodrigues. "A feitiçaria Andina na Conquista do Peru : as plantas nos documentos de extirpação de idolatrias e tratados médicos nos séculos XVI e XVII /". Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/152616.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A expansão marítima proporcionou ao homem europeu o contato com o Novo Mundo, onde se relacionaram com culturas, tradições e costumes diferentes. Levando consigo nas naus o imaginário mágico europeu, as práticas dos povos andinos foram interpretadas como sobrenaturais pelos espanhóis nos dois primeiros séculos da colonização. Nesse sentido,o presente trabalho tem como intenção compreender como os costumes indígenas nos séculos XVI e XVII onde hoje temos localizado o território do Peru foram encarados como feitiçaria pelos espanhóis.Tendo como foco a utilização de plantas, também será analisado de que forma as ervas nesse mesmo momento foram utilizadas como inovação farmacêutica e medicinal. Para isso, investigaremos os documentos de extirpação de idolatrias do Arquivo Arzobispal de Lima, o tratado do médico sevilhano Nicolás Monardes, e as contribuições dos jesuítas Bernabé Cobo e Joseph de Acosta sobre as descrições da natureza americana. Assim, pretende-se contribuir para a compreensão das diferentes abordagens e o que elas representavam naquele contexto, pois enquanto de um lado temos o pensamento do homem europeu marcado pelo imaginário mágico, de outro temos mais de um pensamento racional que buscou lucro, inovação científica e progresso urbano, gerando diversos renascimentos e nos mostrando vários prismas desse período histórico
The maritime expansion has provided the European man the contact with the New World, where they related to cultures, traditions and different habits. Taking with the ships the magical European imaginary, even though the practices of the Andean people were considered supernatural by the Spanish in the 16th and 17th centuries. The present study intends to comprehend how the native habits from the period, where nowadays is located the Peruvian territory, were viewed as witchcraft, focusing in the usage of plants. In contrast, it will be analyzed how the herbs from that same moment were used as pharmaceutical and medicinal innovations. For that, we will consider the documents of extirpation of idolatry from the Arzobispal de Lima Archive, the Sevillian medic Nicolás Monardes’ treaty, and the contributions from the Jesuits Bernabé Cobo and Joseph de Acosta about the descriptions of the American nature. Therefore, we expect to contribute with the comprehension of the different insights and what they represented in that context, since while in one side we have the European man’s way of thinking marked by the magical imaginary, on the other one we have more than one rational thinking that sought profit, scientific innovation and urban progress generating many revivals, showing us several prisms from that historical period.
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Paula, Simone de. "Avalia??o dose-resposta da administra??o intravenosa de c?lulas-tronco de cord?o umbilical humano em modelo de hip?xia-isquemia neonatal em ratos". Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2011. http://tede2.pucrs.br/tede2/handle/tede/1367.

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Introdu??o: A les?o cerebral hip?xico-isqu?mica neonatal (HI) ? uma das maiores causas de mortalidade e morbidade neurol?gica em crian?as. O sangue do cord?o umbilical humano, rico em c?lulas-tronco adultas, ? uma fonte potencial para a terapia celular em perinatologia. No entanto, apesar do efeito ben?fico mostrado na maioria dos estudos, ainda n?o h? consenso em rela??o ? dose adequada de c?lulas-tronco de cord?o umbilical humano (CTCUH) no tratamento da HI. Objetivo: Comparar os efeitos comportamentais e morfol?gicos da administra??o intravenosa de tr?s diferentes doses de CTCUH 8 semanas ap?s a indu??o da HI em ratos rec?m-nascidos. Al?m disso, objetivou-se verificar a presen?a das c?lulas no c?rebro dos animais em estudo 7 dias ap?s o transplante. M?todos: Ratos Wistar de 7 dias de vida foram submetidos ? oclus?o da art?ria car?tida direita seguida por exposi??o a ambiente hip?xico (8% O2) por 2 h. Ap?s 24 h, os ratos foram randomizados em 5 grupos experimentais: ratos cirurgia-simulada; ratos HI que receberam ve?culo (HI + ve?culo); e ratos HI que receberam 1 x 106 (HI + dose baixa), 1 x 107 (HI + dose m?dia); or 1 x 108 (HI + dose alta) CTCUH na veia jugular. A mem?ria de orienta??o espacial foi avaliada atrav?s do labirinto aqu?tico de Morris e, posteriormente, os ratos foram sacrificados para as avalia??es morfol?gicas quantitativas. Adicionalmente, a presen?a das CTCUH no c?rebro dos animais tratados foi verificada atrav?s de t?cnicas de imunofluoresc?ncia e da an?lise de PCR. Resultados: Oito semanas ap?s o transplante, o teste do labirinto aqu?tico de Morris mostrou uma significativa recupera??o da mem?ria de orienta??o espacial nos ratos do grupo HI + dose alta quando comparados aos animais n?o tratados (P < 0,05). Al?m disso, a atrofia cerebral foi significativamente menor nos grupos HI + dose m?dia e alta quando comparados aos animais HI + ve?culo (P < 0,01; 0,001, respectivamente). CTCUH foram localizadas no c?rebro dos ratos que receberam o transplante celular 7 dias ap?s a administra??o intravenosa. Conclus?o: Os resultados mostrados neste estudo revelaram que o transplante intravenoso de CTCUH tem potencial dose-dependente para promover o reparo neuro-tecidual e a est?vel recupera??o cognitiva ap?s les?es hip?xico-isqu?micas.
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Roller, Steffen. "Pflegebedürftigkeit : eine Analyse der 14, 15 SGB XI mit ihren rechtlich-systematischen und pflegewissenschaftlichen Bezügen /". Baden-Baden : Nomos, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015859797&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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BRITO, Thiago Rodrigues. "Medição de módulos fotovoltaicos a sol real por meio de dupla carga capacitiva". Universidade Federal do Pará, 2018. http://repositorio.ufpa.br/jspui/handle/2011/10452.

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Com a crescente demanda de energia elétrica ao redor do mundo, cada vez mais as fontes renováveis de energia vêm adquirindo espaço na matriz energética mundial. Nesse contexto, a energia fotovoltaica tem se destacado com altos índices de crescimento. Contudo, com a sua inserção faz-se necessário dispor de meios para avaliação do desempenho dos módulos fotovoltaicos, que pode ser realizado através da obtenção de sua curva característica I-V. A partir desta os parâmetros elétricos do módulo podem ser definidos, além de ser um indicador de possíveis falhas de fabricação, conexão ou possível sombreamento das células. Através do uso de simuladores solares, tornou-se mais rápido e confiável a obtenção de tal curva. No entanto, os altos custos de um simulador limitam o acesso a tal tipo de medição e, além disso, estes se restringem ao ensaio individual de módulos. Este trabalho busca avaliar uma metodologia para aquisição de curva I-V sob sol-real. Para isto, foram utilizadas duas cargas capacitivas e um módulo de referência para medida de irradiância e temperatura de operação do gerador fotovoltaico. As condições padrões de teste são obtidas por meio do que é descrito na norma IEC 60891. Módulos de tecnologia de silício foram testados e seus resultados confrontados com o do simulador solar presente no laboratório do GEDAE/UFPA. Os resultados obtidos indicam que dependendo da forma de cálculo e considerações acerca da medição da temperatura, esta pode ser uma metodologia adequada para medição de módulos fotovoltaicos em campo.
With the increasing demand for electricity worldwide, renewable energy sources are increasingly acquiring space in the world’s energy matrix. In this context, photovoltaic energy has stood out with high growth rates. However, it is necessary to have means to evaluate the performance of the photovoltaic modules. This can be done by means of its characteristic I-V curve, from which the module’s electrical parameters can be evaluated and used as an indicator of possible manufacturing faults, connection or shading. The use of solar simulators is a faster and more reliable to obtain such I-V curve. However, the high costs of a simulator limits access to such measurement, moreover, it is limited to measure only a single PV module. This work seeks to evaluate a methodology for the I-V curve acquisition under outdoor conditions by using two capacitive loads and a reference module as irradiance and temperature sensor. The standard test conditions are obtained by means of IEC 60891 procedures. Silicon technology modules were tested and their results were compared with indoor measurement, using the solar simulator located at GEDAE/UFPA solar laboratory. The results indicated that, depending on which calculation method and considerations related to temperature, this can be a suitable methodology for the measurement of a photovoltaic module.
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Bhattacharya, Debarpan. "A Learnable Distillation Approach For Model-agnostic Explainability With Multimodal Applications". Thesis, 2023. https://etd.iisc.ac.in/handle/2005/6108.

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Deep neural networks are the most widely used examples of sophisticated mapping functions from feature space to class labels. In the recent years, several high impact decisions in domains such as finance, healthcare, law and autonomous driving, are made with deep models. In these tasks, the model decisions lack interpretability, and pose difficulties in making the models accountable. Hence, there is a strong demand for developing explainable approaches which can elicit how the deep neural architecture, despite the astounding performance improvements observed in all fields, including computer vision, natural language processing, generates the output decisions. The current frameworks for explainability of deep models are based on gradients (eg. GradCAM, guided-gradCAM, Integrated gradients etc) or based on locally linear assumptions (eg. LIME). Some of these approaches require the knowledge of the deep model architecture, which may be restrictive in many applications. Further, most of the prior works in the literature highlight the results on a set of small number of examples to illustrate the performance of these XAI methods, often lacking statistical evaluation. This thesis proposes a new approach for explainability based on mask estimation approaches, called the Distillation Approach for Model-agnostic Explainability (DAME). The DAME is a saliency-based explainability model that is post-hoc, model-agnostic (applicable to any black box architecture), and requires only query access to black box. The DAME is a student-teacher modeling approach, where the teacher model is the original model for which the explainability is sought, while the student model is the mask estimation model. The input sample is augmented with various data augmentation techniques to produce numerous samples in the immediate vicinity of the input. Using these samples, the mask estimation model is learnt to generate the saliency map of the input sample for predicting the labels. A distillation loss is used to train the DAME model, and the student model tries to locally approximate the original model. Once the DAME model is trained, the DAME generates a region of the input (either in space or in time domain for images and audio samples, respectively) that best explains the model predictions. We also propose an evaluation framework, for both image and audio tasks, where the XAI models are evaluated in a statistical framework on a set of held-out of examples with the Intersection-over-Union (IoU) metric. We have validated the DAME model for vision, audio and biomedical tasks. Firstly, we deploy the DAME for explaining a ResNet-50 classifier pre-trained on ImageNet dataset for the object recognition task. Secondly, we explain the predictions made by ResNet-50 classifier fine-tuned on Environmental Sound Classification (ESC-10) dataset for the audio event classification task. Finally, we validate the DAME model on the COVID-19 classification task using cough audio recordings. In these tasks, the DAME model is shown to outperform existing benchmarks for explainable modeling. The thesis concludes with a discussion on the limitations of the DAME approach along with the potential future directions.
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Barros, Sandra Rodrigues. "Tratamento da Leucemia Mielóide Crónica no Séc. XXI". Master's thesis, 2012. https://repositorio-aberto.up.pt/handle/10216/66143.

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Barros, Sandra Rodrigues. "Tratamento da Leucemia Mielóide Crónica no Séc. XXI". Dissertação, 2012. https://repositorio-aberto.up.pt/handle/10216/66143.

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Oliveira, Catarina Inês Alves Lopes de. "Estratégias Terapêuticas no Linfoma de Hodgkin no Século XXI". Dissertação, 2016. https://repositorio-aberto.up.pt/handle/10216/86476.

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Oliveira, Catarina Inês Alves Lopes de. "Estratégias Terapêuticas no Linfoma de Hodgkin no Século XXI". Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/86476.

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Patrão, Ana Rita Azevedo Baía. "Medication before and during pregnancy: data from generation XXI Birth cohort". Master's thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/72442.

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Patrão, Ana Rita Azevedo Baía. "Medication before and during pregnancy: data from generation XXI Birth cohort". Dissertação, 2013. https://repositorio-aberto.up.pt/handle/10216/72442.

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Fernandes, Joana Rita de Sales Gomes. "Diagnose Sexual Através da Clavícula Numa Amostra da Coleção de Esqueletos Identificados do Século XXI". Master's thesis, 2015. https://repositorio-aberto.up.pt/handle/10216/81618.

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Pinto, Pedro Samuel Canoso Alexandre. "Neoplasias em contexto de autópsia médico-legal: ainda causa de morte súbita no século XXI?" Master's thesis, 2017. https://hdl.handle.net/10216/105132.

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Pinto, Pedro Samuel Canoso Alexandre. "Neoplasias em contexto de autópsia médico-legal: ainda causa de morte súbita no século XXI?" Dissertação, 2017. https://hdl.handle.net/10216/105132.

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Fernandes, Joana Rita de Sales Gomes. "Diagnose Sexual Através da Clavícula Numa Amostra da Coleção de Esqueletos Identificados do Século XXI". Dissertação, 2015. https://repositorio-aberto.up.pt/handle/10216/81618.

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Liu, Chin-Chang, i 劉俊昌. "Comparative Study on Medical Thoughts of Miu Xi-Yong and Li Zhong-Zi". Thesis, 2005. http://ndltd.ncl.edu.tw/handle/44444904178169970016.

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博士
中國醫藥大學
中國醫學研究所
93
The mainstream of medical thought during the Ming dynasty was to follow Dan-Xi’s theory of enriching yin and downbearing fire. Many practitioners went too far in this by using bitter cold and fire-downbearing prescriptions to excess. The warm supplementation scholars like Li Zhong-Zi and Miu Xi-Yong rose up to remedy this harmful situation. Li was also one of the great figures of the Yi-Shui school since he recognized that spleen was as important as the kidney for treatment. Miu Xi-Yong was the scholar who upheld the tradition of Liu He-jian and Zhu Dan-Xi and therefore he treated many severe diseases. Miu and Li, while adopting vastly different approaches in the use of medicinals, both achieved clinical efficacy. They provide evidence for the effectiveness of the Chinese medical theory of pattern identification as the basis for determining treatment. The present study seeks to understand the medical thoughts, thinking processes and prescription features of Li and Miu from their academic backgrounds and takes Miu’s Xian-Xing-Zhai-Yi-Xue-Guang-Bi-Ji and Li’s Yi-Zong-Bi-Du and Shan-Bu-Yi-Sheng-Wei-Lun as the source materials. By using inductive, deductive, comparative and analytical methods, this study aims to understand the features of their medical thought and traces the origin and development of supplementation, clearing, yin-enriching methods and the chief characteristics of bowel and visceral pathomechanical pattern identification. These offer guidance for the clinical application of qi-blood-yin-yang theory. The results of the study show that Miu’s approach to healing was based on enriching yin, took the functions of qi and fire into consideration, and laid emphasis on downbearing. He was unique in emphasizing spleen yin and influenced warm disease scholars the use of medicinals in the treatment of damage to yin by warm evil. Li’s approach to healing was based on warming yang and enriching qi in treatment and took attention to functions of yang and qi, and put emphasis on upbearing. He stressed the rule that “in treatment, [one should] seek the root,” emphasized earlier-heaven (congenital) and later-heaven (acquired) constitution, highlighted the importance of correlating pulses and signs to differentiate similar diseases patterns, and united the merits or numerous masters. Miu advocated enriching yin, while Li advocated warming yang. Although their approaches were based on different hypothesis, they both obtained good results in clinic because they mastered Chinese medicine’s principle of identifying patterns as the basis for determining treatment. They both varied their prescription according to constitution, living environment, season, and pathology. The study of the medical thoughts of Miu Xi-Yong and Li Zhong-Zi helps to complete our understanding of the development of the theories of nourishing yin, warming-supplementing, and qi-blood-yin-yang and their clinical application. It represents an approach that might shed light on other theories.
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Pinto, Joana Sofia Moreira. "Dimorfismo Sexual do Sacro na "Coleção de Esqueletos Identificados do Século XXI"". Dissertação, 2015. https://repositorio-aberto.up.pt/handle/10216/81438.

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Janoutová, Martina. "Kultury léčivých rostlin in vitro - XII". Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-310208.

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Martina Janoutová In vitro cultures of medicinal plants - XII. Abstract The effect of ultrasound (US) as abiotic elicitor on the flavonolignans production in Silybum marianum L suspension culture was investigated. The culture was cultivated in Murashige and Skoog nutritive medium with ( - NAO) (g/l) as growth regulator at 25o C and luminous period 16 h of light and 8 h of darkness. The elicitor - ultrasound by frequency 35kHz and intensity 0,1Wcm-3 for a period 1, 2, 3, 4 and 5 min has been used. The samples were taken in 0, 6, 12, 24, 48, 72 and 168 h after US exposition. The control samples were taken in 0 and 48 h. The quantity of flavonolignans was determined by High performance liquid chromatography (HPLC). The highest increase of taxifolin content was apparent after 5 min of US elicitation and 48 h sampling (0,04%) - 400%, other increase was apparent after 5 min of elicitation and 72 h sampling. The higher content of silychristin was found after 1 min of US elicitation and 72 h sampling, the same level was observed after 2 min of elicitation and 24 h sampling. The higher level of silydianin was detected after 2 min of US elicitation and 6 h sampling and the silybin B after 2 min of elicitation and 12 h sampling after exposition. Taxifolin and flavonolignans release to the nutrient medium was...
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Couto, Sandrine da Cunha. "Prevalência de inadequação nutricional em crianças de 4-5 anos da Coorte Geração XXI". Dissertação, 2013. https://repositorio-aberto.up.pt/handle/10216/72378.

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Pinto, Joana Sofia Moreira. "Dimorfismo Sexual do Sacro na "Coleção de Esqueletos Identificados do Século XXI"". Master's thesis, 2015. https://repositorio-aberto.up.pt/handle/10216/81438.

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Beleza, Lia Rafaela Gonçalves Pereira. "Associação entre contraceção hormonal combinada e consumo de tabaco em mães da coorte geração XXI". Dissertação, 2015. https://repositorio-aberto.up.pt/handle/10216/78537.

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Barbosa, Catarina Alexandra Moura. "Influence of parental child-feeding practices on dietary patterns of 7 year-olds from Generation XXI". Dissertação, 2020. https://hdl.handle.net/10216/131288.

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Couto, Sandrine da Cunha. "Prevalência de inadequação nutricional em crianças de 4-5 anos da Coorte Geração XXI". Master's thesis, 2013. https://repositorio-aberto.up.pt/handle/10216/72378.

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Fernandes, Ana Teresa Pereira. "Homícidios por armas de fogo no norte de Portugal : Estudo retrospetivo na primeira década do século XXI". Dissertação, 2012. https://repositorio-aberto.up.pt/handle/10216/71870.

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Beleza, Lia Rafaela Gonçalves Pereira. "Associação entre contraceção hormonal combinada e consumo de tabaco em mães da coorte geração XXI". Master's thesis, 2015. https://repositorio-aberto.up.pt/handle/10216/78537.

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Barbosa, Catarina Alexandra Moura. "Influence of parental child-feeding practices on dietary patterns of 7 year-olds from Generation XXI". Master's thesis, 2020. https://hdl.handle.net/10216/131288.

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Fernandes, Ana Teresa Pereira. "Homícidios por armas de fogo no norte de Portugal : Estudo retrospetivo na primeira década do século XXI". Master's thesis, 2012. https://repositorio-aberto.up.pt/handle/10216/71870.

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Godinho, Maria Manuel Pinheiro. "A estimativa da idade à morte através do acetábulo. A fiabilidade do método de Calce (2012) na Coleção de Esqueletos Identificados do Século XXI". Dissertação, 2016. https://repositorio-aberto.up.pt/handle/10216/86336.

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Huang, Shih-Chang, i 黃世昌. "The Study of the Xi Yuan Ji Lu about Chinese Herbs Poisons and Treatments from the Chinese Medical Classics Literature". Thesis, 2005. http://ndltd.ncl.edu.tw/handle/75363231502872484430.

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碩士
中國醫藥大學
中國醫學研究所
93
The Study of the Xi Yuan Ji Lu about Chinese Herbs Poisons and Treatments from Chinese Medical Classics Literature Shih-Chang Huang Major Professor：Yi-Chang Su Institute of Chinese Medical Science China Medical University, Taiwan Recently, the poisoning accidents of Chinese herbs happened very often; they even attracted attentions of international scholars of modern medicine. Due to its poisonous side effects leading to users’ anxiety or panic, the reputation of Chinese herbs could be further influenced. If based upon Chapter of taking poisons in Song Ci’s Xi Yuan Ji Lu, antidote treatment of interrelated poisoning Chinese herbs. It is believed that users of Chinese medicines and scholars in modern medical fields can have further understanding and confidence on poisonous Chinese herbs. Xi Yuan Ji Lu is a classic of forensic medicine, which is the earliest records summarizing misusing poisonous herbs, diagnosing dead symptoms, identifying poisons, and its antidote prescriptions. We hope to compare, analyze, and induce those poisoning Chinese herbs in books with its related antidote prescriptions in historical Chinese medical classics, and discuss the concepts, ways, and prescriptions of antidote from the perspective of traditional Chinese medicine. Thus, this study focuses on discussing the similarities and differences between poisonous Chinese herbs and its antidote prescriptions in ancient times with the progressive modern medicine and medical technology. By means of modern medicine and technology, it can promote its application on clinical medicine and evidence the values of those historical medical classics. It is hoped that this study can not only benefit those who commit suicide, homicide, or misuse the poisonous Chinese herbs, but also increase people’s understandings about poisonous Chinese herbs. Key words: Xi Yuan Ji Lu, Chinese Herbs Poisons, antidote treatment
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Godinho, Maria Manuel Pinheiro. "A estimativa da idade à morte através do acetábulo. A fiabilidade do método de Calce (2012) na Coleção de Esqueletos Identificados do Século XXI". Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/86336.

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Sojková, Kristýna. "Kultury léčivých rostlin in vitro - XI". Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-309297.

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In vitro cultures of medicinal plants - XI. Elicitation is one of the few strategies that can be used in enhancement of secondary metabolites production from explant cultures. The effect of abiotic elicitor (silver nitrate) on flavonolignan and flavonoid taxifolin production in suspension culture of Silybum marianum L. (Gaertn.) and on isoflavones production in suspension culture of Genista tinctoria L. was tested. Silver nitrate in various concentrations (5.887.10-3 mol/l; 5.887.10-4 mol/l; 5.887.10-5 mol/l) was used as elicitor. Content of secondary metabolites in suspension cultures was determinated by high performance liquid chromatography (HPLC). The samples were taken after 6, 12, 24, 48, 72 and 168 hours after elicitor treatment. The highest content of taxifolin production (0.02 %) in suspension culture of Silybum marianum L. (Gaertn.) after silver nitrate (5.887.10-4 mol/l) treatment and 72 h sampling was detected. The highest content of genistin (0.05 %) in suspension culture of Genista tinctoria L. was found after silver nitrate (5.887.10-4 mol/l) treatment and 48 h sampling. The highest content of daidzein (0.09 %) was detected after elicitor (5.887.10-4 mol/l) treatment and 168 h sampling.
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Monjardino, Maria Teresa Pegado Barroso Abilheira. "Effects of growth on childhood bone status: A study in the Generation XXI birth cohort". Doctoral thesis, 2019. https://hdl.handle.net/10216/120695.

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Monjardino, Maria Teresa Pegado Barroso Abilheira. "Effects of growth on childhood bone status: A study in the Generation XXI birth cohort". Tese, 2019. https://hdl.handle.net/10216/120695.

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Costa, Daniela Alexandra Ferreira da. "The effect of sugar-sweetened beverages on children´s appetitive behaviours: a prospective approach from the Generation XXI birth cohort". Master's thesis, 2019. https://hdl.handle.net/10216/124804.

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Costa, Daniela Alexandra Ferreira da. "The effect of sugar-sweetened beverages on children´s appetitive behaviours: a prospective approach from the Generation XXI birth cohort". Dissertação, 2019. https://hdl.handle.net/10216/124804.

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Pinto, Andreia Pinho. "Obesity-related dietary patterns in 7 years-old children from Generation XXI and their effects in cardiometabolic health later in life". Master's thesis, 2019. https://hdl.handle.net/10216/118742.

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Pinto, Andreia Pinho. "Obesity-related dietary patterns in 7 years-old children from Generation XXI and their effects in cardiometabolic health later in life". Dissertação, 2019. https://hdl.handle.net/10216/118742.

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Guimarães, Bruno Tiago dos Santos. "O uso de novas tecnologias no ensino da anatomia com vista à prática médica no século XXI: o desafio da educação médica". Doctoral thesis, 2019. https://hdl.handle.net/10216/120641.

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Guimarães, Bruno Tiago dos Santos. "O uso de novas tecnologias no ensino da anatomia com vista à prática médica no século XXI: o desafio da educação médica". Tese, 2019. https://hdl.handle.net/10216/120641.

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Guimarães, Susana Filipa Machado. "Family and sociodemographic influences on the pain experience of 7-year-old children as reported by parents - a study of the Generation XXI birth cohort". Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/89525.

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