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Gotowe bibliografie tematyczne / Mechanism of action / Artykuły w czasopismach

Artykuły w czasopismach na temat „Mechanism of action”

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Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 29 lipca 2024

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1

Dubey, Bidhyut Kumar, Mohini Chaurasia i Jyoti Yadav. "ACTIVE CHEMICAL CONSTITUENTS FROM MEDICINAL PLANTS AND MECHANISM OF ACTION AS ANTIPARKINSONIAN". Era's Journal of Medical Research 7, nr 1 (czerwiec 2020): 120–25. http://dx.doi.org/10.24041/ejmr2019.120.

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Dubey, Bidhyut Kumar, Mohini Chaurasia i Jyoti Yadav. "ACTIVE CHEMICAL CONSTITUENTS FROM MEDICINAL PLANTS AND MECHANISM OF ACTION AS ANTIPARKINSONIAN". Era's Journal of Medical Research 7, nr 1 (czerwiec 2020): 120–25. http://dx.doi.org/10.24041/ejmr2020.20.

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3

Edwards, David I. "Nitroimidazole drugs-action and resistance mechanisms I. Mechanism of action". Journal of Antimicrobial Chemotherapy 31, nr 1 (1993): 9–20. http://dx.doi.org/10.1093/jac/31.1.9.

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4

Zhong, Shan, Jeong Woo Choi, Nadia G. Hashoush, Diana Babayan, Mahsa Malekmohammadi, Nader Pouratian i Vassilios Christopoulos. "A neurocomputational theory of action regulation predicts motor behavior in neurotypical individuals and patients with Parkinson’s disease". PLOS Computational Biology 18, nr 11 (17.11.2022): e1010111. http://dx.doi.org/10.1371/journal.pcbi.1010111.

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Surviving in an uncertain environment requires not only the ability to select the best action, but also the flexibility to withhold inappropriate actions when the environmental conditions change. Although selecting and withholding actions have been extensively studied in both human and animals, there is still lack of consensus on the mechanism underlying these action regulation functions, and more importantly, how they inter-relate. A critical gap impeding progress is the lack of a computational theory that will integrate the mechanisms of action regulation into a unified framework. The current study aims to advance our understanding by developing a neurodynamical computational theory that models the mechanism of action regulation that involves suppressing responses, and predicts how disruption of this mechanism can lead to motor deficits in Parkinson’s disease (PD) patients. We tested the model predictions in neurotypical individuals and PD patients in three behavioral tasks that involve free action selection between two opposed directions, action selection in the presence of conflicting information and abandoning an ongoing action when a stop signal is presented. Our results and theory suggest an integrated mechanism of action regulation that affects both action initiation and inhibition. When this mechanism is disrupted, motor behavior is affected, leading to longer reaction times and higher error rates in action inhibition.

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5

Kubala Havrdová, Eva. "Cladribine - mechanism of action". Neurologie pro praxi 18, Suppl.F (1.12.2017): 5–8. http://dx.doi.org/10.36290/neu.2017.122.

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6

Rodan, Gideon, i Alfred Reszka. "Bisphosphonate Mechanism of Action". Current Molecular Medicine 2, nr 6 (1.09.2002): 571–77. http://dx.doi.org/10.2174/1566524023362104.

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7

KASUGA, Masato. "Mechanism of Insulin Action". Folia Endocrinologica Japonica 69, nr 10 (1993): 1029–34. http://dx.doi.org/10.1507/endocrine1927.69.10_1029.

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8

Hurtley, Stella M. "ISRIB mechanism of action". Science 359, nr 6383 (29.03.2018): 1480.8–1481. http://dx.doi.org/10.1126/science.359.6383.1480-h.

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9

Weiner, George J. "Rituximab: Mechanism of Action". Seminars in Hematology 47, nr 2 (kwiecień 2010): 115–23. http://dx.doi.org/10.1053/j.seminhematol.2010.01.011.

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10

Fuller, Ray W., Charles M. Beasley, Robert A. King, George M. Anderson, Ann Rasmusson i Mark A. Riddle. "Fluoxetine Mechanism of Action". Journal of the American Academy of Child & Adolescent Psychiatry 30, nr 5 (wrzesień 1991): 849. http://dx.doi.org/10.1097/00004583-199109000-00030.

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11

King, Robert A., George M. Anderson, Ann Rasmusson i Mark A. Riddle. "Fluoxetine Mechanism of Action". Journal of the American Academy of Child & Adolescent Psychiatry 30, nr 5 (wrzesień 1991): 849. http://dx.doi.org/10.1097/00004583-199109000-00031.

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12

Espinal, Joe. "Mechanism of insulin action". Nature 328, nr 6131 (sierpień 1987): 574–75. http://dx.doi.org/10.1038/328574a0.

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13

Fuller, Ray W., i Charles M. Beasley. "Fluoxetine mechanism of action". Journal of the American Academy of Child & Adolescent Psychiatry 30, nr 5 (wrzesień 1991): 849. http://dx.doi.org/10.1016/s0890-8567(10)80032-2.

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14

Marians, Kenneth J., i Hiroshi Hiasa. "Mechanism of Quinolone Action". Journal of Biological Chemistry 272, nr 14 (4.04.1997): 9401–9. http://dx.doi.org/10.1074/jbc.272.14.9401.

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15

Drlica, Karl. "Mechanism of fluoroquinolone action". Current Opinion in Microbiology 2, nr 5 (październik 1999): 504–8. http://dx.doi.org/10.1016/s1369-5274(99)00008-9.

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16

Weller, Stephen C. "Herbicide Mechanism of Action". Weed Science 39, nr 3 (wrzesień 1991): 427. http://dx.doi.org/10.1017/s0043174500073185.

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17

Zhanel, George G., Frank Schweizer i James A. Karlowsky. "Oritavancin: Mechanism of Action". Clinical Infectious Diseases 54, suppl_3 (15.04.2012): S214—S219. http://dx.doi.org/10.1093/cid/cir920.

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18

Baudrand, Rene, Luminita H. Pojoga, Jose R. Romero i Gordon H. Williams. "Aldosteroneʼs mechanism of action". Current Opinion in Nephrology and Hypertension 23, nr 1 (styczeń 2014): 32–37. http://dx.doi.org/10.1097/01.mnh.0000436543.48391.e0.

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19

Trabalzini, Lorenza. "Khellin: Mechanism of action". Journal of Photochemistry and Photobiology B: Biology 9, nr 3-4 (czerwiec 1991): 403–4. http://dx.doi.org/10.1016/1011-1344(91)80198-q.

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20

Reszka, Alfred A., i Gideon A. Rodan. "Bisphosphonate mechanism of action". Current Rheumatology Reports 5, nr 1 (styczeń 2003): 65–74. http://dx.doi.org/10.1007/s11926-003-0085-6.

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21

ORTEGA, LAURA G., MATTHEW D. MCCOTTER, GILBERT L. HENRY, STEPHEN J. MCCORMACK, DANIEL C. THOMIS i CHARLES E. SAMUEL. "Mechanism of Interferon Action". Virology 215, nr 1 (styczeń 1996): 31–39. http://dx.doi.org/10.1006/viro.1996.0004.

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22

Borchardt, Ronald T. "Mechanism of Drug Action". Journal of Pharmaceutical Sciences 74, nr 8 (sierpień 1985): 910. http://dx.doi.org/10.1002/jps.2600740841.

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23

Ali, Ghorbat Saleh. "Mechanism of Action p53". Asian Pacific Journal of Cancer Biology 8, nr 1 (2.03.2023): 63–68. http://dx.doi.org/10.31557/apjcb.2023.8.1.63-68.

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P53 is a 393 residue protein in humans made up of five proposed domains, with which the central DNA binding domain with 100-300 sequences very important for the direct binding of p53 in the promoters of its target genes to specific response elements. P53 is a tumor suppressor gene with cellular stress like oxygen deficiency, oxidative stress, radiation and carcinogens substances, is stimulated has major roles in translational regulation and feedback processes. A wide variety of damage signals that relate to the stability, post-translational alteration and recruitment of p53 to binding sites in chromatin which activate the p53 pathway. As a transcriptional activation, p53 mediates transcriptional changes which facilitate cell death, senescence or reversing and protective arrest of the cell cycle. P53 is a protein under intense investigation because it is necessary to prevent tumor, in human tumors have been found to deregulation of p53 activity. On this article study focuses the mechanism of suppressive p53 effects in the response to any stress and correlation of the mutation p53 with different tumor.

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24

Ali, Ghorbat, i Basim Ahmed. "Mechanism of Action p53". Egyptian Journal of Veterinary Sciences 54, nr 5 (1.11.2023): 941–48. http://dx.doi.org/10.21608/ejvs.2023.205434.1490.

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25

Berry, Marla J., i Charles E. Samuel. "Mechanism of interferon action". Biochemical and Biophysical Research Communications 133, nr 1 (listopad 1985): 168–75. http://dx.doi.org/10.1016/0006-291x(85)91856-x.

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26

Wuttke, Wolfgang, Hubertus Jarry i Dana Seidlovα-Wuttke. "Definition, classification and mechanism of action of endocrine disrupting chemicals". HORMONES 9, nr 1 (15.01.2010): 15. http://dx.doi.org/10.14310/horm.2002.1252.

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27

Goddette, D. W., i C. Frieden. "Actin polymerization. The mechanism of action of cytochalasin D." Journal of Biological Chemistry 261, nr 34 (grudzień 1986): 15974–80. http://dx.doi.org/10.1016/s0021-9258(18)66662-1.

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28

Greene, Stephen J., i Mihai Gheorghiade. "Matching Mechanism of Death With Mechanism of Action". Journal of the American College of Cardiology 64, nr 15 (październik 2014): 1599–601. http://dx.doi.org/10.1016/j.jacc.2014.06.1199.

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29

Brin, Mitchell F., i Rami Burstein. "Botox (onabotulinumtoxinA) mechanism of action". Medicine 102, S1 (1.07.2023): e32372. http://dx.doi.org/10.1097/md.0000000000032372.

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Studies in the 1920s found that botulinum neurotoxin type A (BoNT/A) inhibited the activity of motor and parasympathetic nerve endings, confirmed several decades later to be due to decreased acetylcholine release. The 1970s were marked by studies of cellular mechanisms aided by use of neutralizing antibodies as pharmacologic tools: BoNT/A disappeared from accessibility to neutralizing antibodies within minutes, although it took several hours for onset of muscle weakness. The multi-step mechanism was experimentally confirmed and is now recognized to consist broadly of binding to nerve terminals, internalization, and lysis or cleavage of a protein (SNAP-25: synaptosomal associated protein-25 kDa) that is part of the SNARE (Soluble NSF Attachment protein REceptor) complex needed for synaptic vesicle docking and fusion. Clinical use of the BoNT/A product onabotulinumtoxinA was based on its ability to reduce muscle contractions via inhibition of acetylcholine from motor terminals. Sensory mechanisms of onabotulinumtoxinA have now been identified, supporting its successful treatment of chronic migraine and urgency in overactive bladder. Exploration into migraine mechanisms led to anatomical studies documenting pain fibers that send axons through sutures of the skull to outside the head—a potential route by which extracranial injections could affect intracranial processes. Several clinical studies have also identified benefits of onabotulinumtoxinA in major depression, which have been attributed to central responses induced by feedback from facial muscle and skin movement. Overall, the history of BoNT/A is distinguished by basic science studies that stimulated clinical use and, conversely, clinical observations that spurred basic research into novel mechanisms of action.

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30

Hirabayashi, Yoko, i Tohru Inoue. "Endocrine Disruptors: Mechanism of Action." Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 35, nr 12 (1998): 873–79. http://dx.doi.org/10.3143/geriatrics.35.873.

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31

Wallmark, Björn. "Mechanism of Action of Omeprazole". Scandinavian Journal of Gastroenterology 21, sup118 (styczeń 1986): 11–16. http://dx.doi.org/10.3109/00365528609090881.

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32

Hemaiswarya, S., R. Raja, R. Ravikumar i Isabel S. Carvalho. "Mechanism of action of probiotics". Brazilian Archives of Biology and Technology 56, nr 1 (luty 2013): 113–19. http://dx.doi.org/10.1590/s1516-89132013000100015.

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33

Paolucci, Francis, Marie-Christine Clavi??s, Fran??ois Donat i Jos?? Necciari. "Fondaparinux Sodium Mechanism of Action". Clinical Pharmacokinetics 41, Supplement 2 (2002): 11–18. http://dx.doi.org/10.2165/00003088-200241002-00002.

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34

Seeman, Philip. "Atypical Antipsychotics: Mechanism of Action". FOCUS 2, nr 1 (styczeń 2004): 48–58. http://dx.doi.org/10.1176/foc.2.1.48.

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35

Luyts, N., H. De Bruyn, T. Voets i W. Everaerts. "Mechanism of action of Phenazopyridine". European Urology 81 (luty 2022): S16—S17. http://dx.doi.org/10.1016/s0302-2838(22)00101-4.

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36

Du, Guangqian, Shijie Wang i Jichao Chu. "Mechanism of Action Slope Vegetation". Advance Journal of Food Science and Technology 11, nr 12 (25.08.2016): 805–9. http://dx.doi.org/10.19026/ajfst.11.2796.

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37

Millichap, J. Gordon. "Ketogenic Diet Mechanism of Action". Pediatric Neurology Briefs 10, nr 4 (1.04.1996): 27. http://dx.doi.org/10.15844/pedneurbriefs-10-4-4.

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38

Fox, E. J. "Mechanism of action of mitoxantrone". Neurology 63, Issue 12, Supplement 6 (28.12.2004): S15—S18. http://dx.doi.org/10.1212/wnl.63.12_suppl_6.s15.

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39

Smith, Charles D., i Xinqun Zhang. "Mechanism of Action of Cryptophycin". Journal of Biological Chemistry 271, nr 11 (15.03.1996): 6192–98. http://dx.doi.org/10.1074/jbc.271.11.6192.

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40

Soriano, Alex, i Josep Mensa. "Mechanism of action of cefiderocol". Revista Española de Quimioterapia 35, Suppl2 (4.10.2022): 16–19. http://dx.doi.org/10.37201/req/s02.02.2022.

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Gram-negative bacilli are intrinsically resistant to many antibiotics due to the low permeability of their outer membrane. The most effective strategy to solve this problem has been the design of antibiotics that cross the membrane using specific transport systems. This is the case of cefiderocol, which, unlike cefepime or ceftazidime, has a chlorocatechol group at the end of the C-3 side chain. This group is recognized by transporters located in the outer membrane that allow cefiderocol to accumulate in the periplasmic space. Furthermore, cefiderocol is not a substrate for efflux pumps and the configuration of the side chains at C-7 and in particular at C-3 confer it a high stability against hydrolysis by most beta-lactamases of clinical interest including class A (KPC, BLEEs), C (ampC) or D (OXA-48) serine beta-lactamases and metallo-betalactamases (NDM, VIM. IMP). In order to better understand the mechanism of action of cefiderocol, the importance of iron in bacterial metabolism and the competition for iron between bacteria and host are reviewed.

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41

Garlid, K. D., M. Jaburek i P. Jezek. "Mechanism of uncoupling protein action". Biochemical Society Transactions 29, nr 6 (1.11.2001): 803–6. http://dx.doi.org/10.1042/bst0290803.

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Two competing models of uncoupling protein (UCP) transport mechanism agree that fatty acids (FAs) are obligatory for uncoupling, but they disagree about which ion is transported. In Klingenberg's model, UCPs conduct protons. In Garlid's model, UCPs conduct anions, like all members of this gene family. In the latter model, UCP transports the anionic FA head group from one side of the membrane to the other, and the cycle is completed by rapid flip-flop of protonated FAs across the bilayer. The head groups of the FA analogues, long-chain alkylsulphonates, are translocated by UCP, but they cannot induce uncoupling, because these strong acids cannot be protonated for the flip-flop part of the cycle. We have overcome this limitation by ion-pair transport of undecanesulphonate with propranolol, which causes the sulphonate to deliver protons across the membrane as if it were an FA. Full GDP-sensitive uncoupling is seen in the presence of propranolol and undecanesulphonate. This result confirms that the mechanism of UCP uncoupling requires transport of the anionic FA head group by UCP and that the proton transport occurs via the bilayer and not via UCP.

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42

Garlid, K. D., M. Jaburek i P. Jezek. "Mechanism of uncoupling protein action". Biochemical Society Transactions 29, nr 5 (1.10.2001): A100. http://dx.doi.org/10.1042/bst029a100b.

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43

Goodwin, G. M. "Mechanism of action of lithium". Current Opinion in Psychiatry 1, nr 1 (styczeń 1988): 72–75. http://dx.doi.org/10.1097/00001504-198801000-00014.

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44

Goodwin, G. M. "Mechanism of action of lithium". Current Opinion in Psychiatry 2, nr 1 (luty 1989): 117–18. http://dx.doi.org/10.1097/00001504-198902000-00028.

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Graham, Garry G., i Kieran F. Scott. "Mechanism of Action of Paracetamol". American Journal of Therapeutics 12, nr 1 (styczeń 2005): 46–55. http://dx.doi.org/10.1097/00045391-200501000-00008.

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46

CREASEY, N. H., A. C. ALLENBY i C. SCHOCK. "MECHANISM OF ACTION OF ACCELERANTS". British Journal of Dermatology 85, nr 4 (29.07.2006): 368–80. http://dx.doi.org/10.1111/j.1365-2133.1971.tb14032.x.

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LIU, LEROY F., SHYAMAL D. DESAI, TSAI-KUN LI, YONG MAO, MEI SUN i SAI-PENG SIM. "Mechanism of Action of Camptothecin". Annals of the New York Academy of Sciences 922, nr 1 (25.01.2006): 1–10. http://dx.doi.org/10.1111/j.1749-6632.2000.tb07020.x.

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Piddock, L. J., M. C. Hall i R. Wise. "Mechanism of action of lomefloxacin." Antimicrobial Agents and Chemotherapy 34, nr 6 (1.06.1990): 1088–93. http://dx.doi.org/10.1128/aac.34.6.1088.

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Disis, Mary L. "Mechanism of Action of Immunotherapy". Seminars in Oncology 41 (październik 2014): S3—S13. http://dx.doi.org/10.1053/j.seminoncol.2014.09.004.

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Haskett, Roger F. "Electroconvulsive Therapy’s Mechanism of Action". Journal of ECT 30, nr 2 (czerwiec 2014): 107–10. http://dx.doi.org/10.1097/yct.0000000000000143.

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