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Ma, Chuanhong. "MCE training basd continuous density HMM landmine detection system /". free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p1418048.
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Hilding, Fredrik, i Rebecca Ilehag. "Visualization and Analysis of Historical OHCA Occurrences and Other Risk Factors for Improved Placement of AEDs". Thesis, KTH, Geodesi och geoinformatik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-147186.
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When an out of hospital cardiac arrest (OHCA) occurs, time is of the utmost importance. For every minute that the arrest goes untreated, the chance of survival decreases rapidly. The most common treatment, that is also the most known, is Cardiopulmonary Resuscitation (CPR). Thanks to new technology, the defibrillator is no longer a tool only available to hospital personnel but to anyone who knows where they are located. The objective of this thesis is partly to visualize OHCA occurrences as well as visualize the differences in OHCA occurrences between locations and years. The thesis will analyze where the optimal locations of AEDs are based on a number of variables such as location and year, which is referred to as risk analysis. The analysis was performed by using daytime and nighttime population data from Statistics Sweden (SCB) in combination with heart disease statistics from the national patient register of Socialstyrelsen as well as socio-economic data from SCB. Along with that data, AED locations at the end of 2013 and OHCA data from 2006 up until 2013 was used in visualizations and risk analysis. In order to determine the final optimal placement through the risk analysis, a Geographical Information System (GIS) tool named Multi-Criteria Evaluation (MCE) was used. This tool enabled the weighting of the different parameters against each other, which was integral for the final result. In order to visualize differences, e.g. between two years, a raster was created which consisted of a density difference between the two years. This analysis method shows the spots where there is a majority of either case, e.g. if one area had a larger number of OHCA cases one year compared to previous year. Simple plots were included to show an overview of the problem e.g. where OHCA occurred between the years 2006 and 2013. The results implied that the recommended locations of AEDs while using daytime population data were located in commercial areas. Recommended AEDs from using the nighttime population data was located differently but was located as well as clusters in residential areas. A large source of error in the analysis was the prior heart disease data. The chosen method, an assignment of a percentage chance of heart disease per age group, is a rough and inexact approximation of the actual heart disease statistics. Had there been data about exactly where patients with prior heart disease live and work, the results would most likely be even better.När ett hjärtstopp utanför sjukhus (OHCA) inträffar, är tiden av yttersta vikt. För varje minut som hjärtstoppet går obehandlat minskar snabbt chansen för överlevnad. Den vanligaste behandlingen, som även är den mest kända, är hjärt- och lungräddning. Tack vare ny teknik är defibrillatorn inte längre ett verktyg som endast är tillgänglig för sjukvårdspersonal utan för alla som vet var de finns. Syftet med denna uppsats är att delvis visualisera förekomsten av OHCA men även att åskådliggöra skillnaderna mellan platser och år. I studien analyseras även, baserat på ett antal variabler, var de optimala platserna för Automatiska Externa Defibrillatorer (AED) är. Denna del av analysen är benämnd som riskanalys. Analysen genomfördes med hjälp av att använda dag- och nattidsbefolkningsdata från Statistiska Centralbyrån (SCB) i kombination med hjärtsjuksdomsstatistik från Socialstyrelsens nationella patientsregister och även socioekonomiska data från SCB. Dessa data, samt AED data från slutet av 2013 och OHCA data daterat från 2006 till 2013 användes både till visualiseringen och till riskanalysen. För att bestämma de slutgiltiga optimala platserna genom riskanalysen användes ett Geografiskt Information System (GIS) verktyg som heter multikriterieanalys (MCE). Detta verktyg gör det möjligt att vikta de olika parametrarna mot varandra, vilket var väsentligt för det slutgiltiga resultatet. För att kunna visualisera skillnader, till exempel mellan två år, skapades ett raster som bestod av en densitetskillnad mellan de två åren. Denna analysmetod kunde sedan visualisera var det finns en majoritet av det ena fallet, till exempel om ett område hade fler hjärtstopp ett år jämfört med tidigare år. Enklare kartor användes för att ge en översikt, till exempel var OHCA har skett mellan åren 2006 och 2013. Resultatet tyder på att de rekommenderade platserna för AED då dagtidsbefolkningsdata användes hamnade i områden med många arbetsplatser. De optimala platserna för AED med nattidsbefolkningsdata var annorlunda utplacerade men hamnade även dem i kluster i befolkningstäta områden med mycket bostäder. En av de större felkällorna i analysen tros vara hjärtsjuksdomsstatistiken. Den metod som användes var att extrahera ålder- och könsgrupper från ett patientregister vilket är en grov och inexakt approximation av den faktiska hjärtsjuksdomsstatistiken. Hade tillgång till data om var befolkning med hjärtsjukdomar faktiskt bor och arbetar funnits, kunde resultatet blivit mer pålitligt.
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Dávila, Flores Humberto Arturo. "Cambios en la representación social del conocimiento". Thesis, Universidad de las Américas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/davila_f_ha/.
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Este trabajo explora el uso de la noción de "Representación
Social" (Moscovici, S., 1961) en la evaluación de cambios en el
conocimiento acerca de un objeto específico, con el cual se supone
está familiarizada la población escolar de una área
geográfica.
Con tal fin se combinan las técnicas de redes semánticas naturales
(Figueroa, González y Solis, 1981) y el diferencial semántico
(Osgood, Succi & Tannenbaum, 1967) en la construcción de un artefacto
experimental.
El instrumento consta de dos encuestas aplicadas en dos tiempos distintos,
dentro del intervalo de un mismo periodo semestral, a una muestra aleatoria
de escolares de la misma área urbana (Cuautlancingo, San Andrés
Cholula y San Pedro Cholula, en el Estado de Puebla).
La muestra contó con la participación de 366 escolares, tanto
del sector público como del privado, de distintas instituciones de
Educación Primaria, Secundaria, Bachillerato y Licenciatura.
Los resultados del análisis estadístico se han interpretado
desde la perspectiva de la teoría del núcleo central (Abric,
J-C, 1994), asumiendo que hay una génesis en la "representación
social" (Duveen & Lloyd, 1990), una estructura (Chi, M., 2006) y una
"práctica deliberada" (Ericsson y colaboradores, 1997) en la
adquisición, modificación y conservación de la misma.
Las transformaciones e invariancias observadas se evalúan en los
términos de un modelo simple del desarrollo de conocimiento experto
(Dreyfus y Dreyfus, 1980).
Finalmente, se ensaya con dos formas de representar gráficamente la
correspondencia entre el nivel de escolaridad y el conocimiento de los
estudiantes acerca del objeto específico "Tecnologías de
Información y Comunicación".(cont.) La primera está basada en la homología de un sistema de masas que giran en torno de un centro de gravedad, o la situación del centroide de un constructo sobre el vértice de una sección cónica en el espacio unitario multivariable (Little y colaboradores, 1999). La otra, incorporando sobre una red tridimensional de vínculos y nodos los parámetros que el artefacto propuesto permite definir. Esta última tiene la ventaja de que puede construirse con gran facilidad mediante el "software" disponible para los mapas conceptuales ( http://cmap.ihmc.us/ ). Investigaciones de campo recientes han aplicado instrumentos con una metodología parecida, enfocando en otras regiones de nuestro país precisamente el mismo objeto de conocimiento (cf. Zermeño, Arellano y Ramírez, 2005). Así que la identificación de patrones mesurables en el dominio del conocimiento previo puede extraer elementos de juicio útiles, aprovechando el contraste que el presente estudio procura. San Andrés Cholula, Pue., mayo de 2010 .
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Bonilla, Mendoza Ana Lilia María. "La Educación Popular y sus posibilidades en la Educación Formal". Thesis, Universidad de las Américas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/bonilla_m_al/.
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P��rez, De Le��n Marina. "Sistematizaci��n de la estrategia de formaci��n de j��venes voluntarios desarrollada por un educador social. El caso de una Organizaci��n Civil, el Centro de Comunicaci��n Popular". Thesis, Universidad de las Am��ricas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/perez_d_m/.
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S��nchez, Sol��s Mariana. "TIC y transformaci��n docente: cambios en el conocimiento, las creencias pedag��gicas y la auto-percepci��n. Estudio de Casos en telesecundarias rurales". Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/sanchez_s_m/.
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El presente estudio tiene como foco de inter��s el uso de las tecnolog��as de la informaci��n y la comunicaci��n como detonadores de la transformaci��n del conocimiento, las creencias pedag��gicas y la auto-percepci��n de los maestros. Esta investigaci��n fue realizada en escuelas telesecundarias rurales de la mixteca y la sierra norte del estado de Puebla. La metodolog��a responde al estudio de casos de una muestra de ocho docentes. Los resultados de la investigaci��n permiten establecer la transformaci��n que sufren los docentes en cuanto a su conocimiento tecnol��gico, sus creencias pedag��gicas y forma en que se auto perciben, as�� como las implicaciones que esta transformaci��n trae consigo.
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Gonz��lez, List Ver��nica. "Aprendizajes no intencionados en las organizaciones y movimientos civiles en M��xico entre 2002-2012 ��Qu�� nos dicen la investigaci��n y los conocedores expertos?" Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/gonzalez_l_v/.
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Este trabajo es un estudio exploratorio-descriptivo que recoge y documenta lo concerniente con respecto al v��nculo entre aprendizajes no intencionados y procesos aglutinantes de la sociedad civil. Forma parte de un estudio m��s amplio sobre los estados del conocimiento en M��xico en la ��ltima d��cada (2002-2012) elaborados por el Consejo Mexicano de Investigaci��n Educativa (COMIE).
Poco sabemos con respecto a lo que se aprende, sin que se tuviera la intenci��n, por participar en procesos civiles organizados que generalmente surgen por situaciones de exclusi��n, pobreza, violencia o injusticia. Aportar a la comprensi��n de la dimensi��n educativa de lo que ocurre dentro de los movimientos y las organizaciones sociales, es el objeto de este estudio.
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Castillo, Sanguino Narciso. "Las TIC como herramienta docente para fortalecer la identidad cultural: estudio de casos en telesecundarias rurales de Puebla". Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/castillo_s_n/.
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El equipamiento con TIC a las escuelas rurales corre de manera vertiginosa. Las TIC en las escuelas est��n generando otro tipo de din��micas. La incorporaci��n de las TIC enfrenta el reto de dotarlas de sentido tanto a nivel individual como colectivo. Este estudio de corte cualitativo se inserta dentro de este contexto. La pregunta de la que naci�� fue: ��pueden las TIC ser aplicadas para fortalecer la identidad culturalα Se utiliz�� la metodolog��a de estudio de casos seleccionando 4 casos (profesores que trabajan en zonas rurales) en el estado de Puebla. El modo de aproximaci��n al fen��meno de estudio fue a trav��s de entrevistas y documentos y teniendo como referente te��rico conceptual la Teor��a del Control Cultural de Bonfil. En base a la pregunta focal, se encontr�� que las TIC pueden encausar el fortalecimiento de la identidad cultural siempre y cuando los profesores sometan a las TIC a un proceso de apropiaci��n en t��rminos del control cultural.
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Sun, Yu. "Simulating Future Land Use Change in the East Fork Little Miami River (EFLMR) Watershed in Ohio". University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1236277626.
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Fu, Qiang. "A generalization of the minimum classification error (MCE) training method for speech recognition and detection". Diss., Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/22705.
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The model training algorithm is a critical component in the statistical pattern recognition approaches which are based on the Bayes decision theory. Conventional applications of the Bayes decision theory usually assume uniform error cost and result in a ubiquitous use of the maximum a posteriori (MAP) decision policy and the paradigm of distribution estimation as practice in the design of a statistical pattern recognition system. The minimum classification error (MCE) training method is proposed to overcome some substantial limitations for the conventional distribution estimation methods.
In this thesis, three aspects of the MCE method are generalized. First, an optimal classifier/recognizer design framework is constructed, aiming at minimizing non-uniform error cost.A generalized training criterion named weighted MCE is proposed for pattern and speech recognition tasks with non-uniform error cost.
Second, the MCE method for speech recognition tasks requires appropriate management of multiple recognition hypotheses for each data segment.
A modified version of the MCE method with a new approach to selecting and organizing recognition hypotheses is proposed for continuous phoneme recognition. Third, the minimum verification error (MVE) method for detection-based automatic speech recognition (ASR) is studied. The MVE method can be viewed as a special version of the MCE method which aims at minimizing detection/verification errors. We present many experiments on pattern recognition and speech recognition tasks to justify the effectiveness of our generalizations.
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Zhang, Xuping. "Automatic feature learning and parameter estimation for hidden Markov models using MCE and Gibbs sampling". [Gainesville, Fla.] : University of Florida, 2009. http://purl.fcla.edu/fcla/etd/UFE0041157.
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Blänning, Erik, i Caroline Ivarsson. "Assessment of Placing of Field Hospitals After the 2010 Haiti EarthquakeUsing Geospatial Data". Thesis, KTH, Geoinformatik och Geodesi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-98069.
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When natural disasters such as earthquakes happen, there is a need for an efficient method to support humanitarian aid organizations in the decision making process. One such decision is placement of Foreign Field Hospitals to assist with medical help.To support such a decision lots of different information and data needs to be gathered and combined. The main objectives of this thesis are to collect existing data published shortly after the earthquake in Haiti 2010 as well as data published up to two months after the earthquake. The data is then to be evaluated according to adequacy for analysis and the result of the analysis to be compared to the actual placements of the field hospitals after the 2010 earthquake.The method used in this analysis is Multi Criteria Evaluation (MCE). Data regarding population, elevation, roads, land use, damage, climate, water, health facility locations and airport location are collected and weighted relative with the Analytic Hierarchy Process (AHP) with weights retrieved from a questionnaire sent out to Non-Governmental Organizations (NGOs) and countries involved in the disaster relief. The result obtained from the MCE is a final suitability map depicting areas that are suitable according to the different factors.The data availability for the thesis project is an issue, due to lack of data published shortly after the earthquake. Some of the data used in the analysis do not have the sufficient detail level. Still, an analysis can be performed where suitable areas are obtained.The suitable locations found in the analysis agree well in most cases with where the actual FFHs are placed, however a few locations are not in proximity to where the suitable areas lie. A few of the locations were located in areas exposed to frequently floods. Even though the data availability and quality leaves things to desire, the analysis method shows promising results for future research. The approach could help aggregating information from different sources and provide support in pre-dispatch organization, already having a set of suitable locations to arrive to.
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Shin, Sung-Hwan. "Objective-driven discriminative training and adaptation based on an MCE criterion for speech recognition and detection". Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50255.
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Acoustic modeling in state-of-the-art speech recognition systems is commonly based on discriminative criteria. Different from the paradigm of the conventional distribution estimation such as maximum a posteriori (MAP) and maximum likelihood (ML), the most popular discriminative criteria such as MCE and MPE aim at direct minimization of the empirical error rate. As recent ASR applications become diverse, it has been increasingly recognized that realistic applications often require a model that can be optimized for a task-specific goal or a particular scenario beyond the general purposes of the current discriminative criteria. These specific requirements cannot be directly handled by the current discriminative criteria since the objective of the criteria is to minimize the overall empirical error rate.
In this thesis, we propose novel objective-driven discriminative training and adaptation frameworks, which are generalized from the minimum classification error (MCE) criterion, for various tasks and scenarios of speech recognition and detection. The proposed frameworks are constructed to formulate new discriminative criteria which satisfy various requirements of the recent ASR applications. In this thesis, each objective required by an application or a developer is directly embedded into the learning criterion. Then, the objective-driven discriminative criterion is used to optimize an acoustic model in order to achieve the required objective.
Three task-specific requirements that the recent ASR applications often require in practice are mainly taken into account in developing the objective-driven discriminative criteria. First, an issue of individual error minimization of speech recognition is addressed and we propose a direct minimization algorithm for each error type of speech recognition. Second, a rapid adaptation scenario is embedded into formulating discriminative linear transforms under the MCE criterion. A regularized MCE criterion is proposed to efficiently improve the generalization capability of the MCE estimate in a rapid adaptation scenario. Finally, the particular operating scenario that requires a system model optimized at a given specific operating point is discussed over the conventional receiver operating characteristic (ROC) optimization. A constrained discriminative training algorithm which can directly optimize a system model for any particular operating need is proposed. For each of the developed algorithms, we provide an analytical solution and an appropriate optimization procedure.
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Flesselles, Bruno. "Generation et caracterisation d'un mutant du bcg inactive pour le gene d'entree cellulaire des mycobacteries (mce)". Paris 7, 1999. http://www.theses.fr/1999PA077087.
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La tuberculose est la maladie infectieuse qui cause le plus de morts dans le monde chaque annee. L'agent pathogene responsable de ce fleau, mycobacterium tuberculosis, est une bacterie intracellulaire facultative, qui se developpe dans les macrophages de l'hote et a la capacite d'echapper au systeme immunitaire. Parmi les diverses proprietes possedees par les mycobacteries, on peut citer la capacite de penetrer dans les cellules non-phagocytaires, toutefois reduite in vitro et rarement observee in vivo. Toutefois, ce phenomene demontre que les mycobacteries sont capables d'induire les rearrangements cellulaires qui menent a l'internalisation du micro-organisme. Le gene mce (mycobacterial cell entry) a ete isole, comme un candidat pour une telle fonction lors de l'infection. Un mutant de mycobacterium bovis bcg dans lequel ce gene a ete inactive par recombinaison homologue a ete genere. Ce mutant (bcgmce) a ete caracterise et ses proprietes ont ete etudiees. On a montre que bcgmce possede une capacite reduite d'invasion des cellules non-phagocytaires hela par rapport au bcg sauvage, alors qu'il penetre des cellules de type macrophage plus aisement que la bacterie sauvage. Toutefois, sa croissance est alteree dans ces cellules in vitro. Des etudes in vivo ont montre que le mutant induit une pathologie retardee chez les souris immunodeficientes. En revanche, on n'observe pas de differences significatives dans le comportement des deux souches dans des animaux immunocompetents, lors des premieres semaines suivant l'infection. A long terme en revanche, bcgmce persiste de facon plus efficace que le bcg sauvage dans certains organes de ces animaux. Les resultats presentes ici confirment un role de la proteine mce dans les differents phenomenes d'invasion cellulaire, et permettent de la relier aux phenomenes de survie bacterienne dans les cellules et de persistance globale dans l'hote.
15
Peng, Peijing. "Interaction of alpha-gamma-MSH analogues with MC1, MC3 and MC4 melanocortin receptors". Thesis, University of Bath, 1997. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338413.
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López, Urzúa Naima. "Catalizador de cobre soportado en nanoesferas de MCe=2@TIO2 (M= Sm,y) para la eliminación de gases de combustión". Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/147354.
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Título de Química AmbientalLa combustión residencial de biomasa es una fuente de energía común de calefacción y cocina en Chile especialmente en las ciudades del centro y sur. Sin embargo, al mismo tiempo produce importantes cantidades de contaminantes perjudiciales para la salud. El presente trabajo de seminario de título se enfoca en la preparación y caracterización de catalizadores de cobre y potasio soportados en partículas tipo núcleocarcasa: Y2O3CeO2@TiO2 y Sm2O3CeO2@TiO2, y su posterior aplicación a la eliminación de contaminantes provenientes de la combustión de leña, en particular NO y CO. El soporte que consiste de un núcleo (TiO2) y carcasa (CeO2 estabilizado con itrio o samario) fue sintetizado por un método de micela inversa y posteriormente impregnado con precursores de cobre y potasio. Asimismo, con el fin de determinar y relacionar las características superficiales de los catalizadores con su actividad, se utilizaron diversas técnicas de caracterización (TEM, SEM, área BET, XRD, DRIFTS, TPR). En las condiciones estudiadas, los resultados muestran que el catalizador previamente reducido a 500ºC (K/Cu/Sm2O3CeO2@TiO2) es altamente activo en la reducción selectiva de NO con CO en presencia de oxígeno. De hecho, presenta conversión completa de CO desde los 255ºC y un 97% de conversión de NO a partir de los 330ºC. Las especies de cobre altamente dispersas en interacción con la fase de potasio son capaces de reducir NO generando una variedad de especies superficiales de nitratos y nitritos, posteriormente reducidos a N2. Este catalizador basado en cobre y xiii libre de metales nobles posee un alto potencial comercial para su utilización en la eliminación de NO con CO en condiciones oxidantes.
Residential combustion of biomass is a common source of energy for heating and cooking in Chile, especially in central and southern cities. However, at the same time it produces important amounts of pollutants that are harmful to health. The present seminar thesis is focused in the preparation and characterization of copper and potassium based catalysts supported on particles of a core-shell type: Y2O3CeO2@TiO2 and Sm2O3CeO2@TiO2, and its subsequent use in the elimination of pollutants originated from the combustion of firewood, specifically NO and CO. The support consisting of a core (TiO2) and shell (CeO2 stabilized with yttrium or samarium) were synthesized by a reverse micelle method and thereafter impregnated with copper and potassium precursors. In the same way, in order to determine and relate the activity and surface characteristics of the catalysts, a variety of characterization techniques were used (TEM, SEM, BET area, XRD, DRIFTS, TPR). Under the conditions used in this study, the results show that the catalyst previously reduced at 500oC (K/Cu/Sm2O3CeO2@TiO2) is highly active in the selective reduction of NO with CO in the presence of oxygen. In fact, it shows full conversion of CO from 255oC and 97% conversion of NO from 330oC. The highly dispersed copper species interacting with the potassium phase are able to reduce NO, further generating a variety of surface nitrite and nitrate species, which are then reduced to N2. This copperbased catalyst, free of noble-metals, possesses a high commercial potential for being used in the elimination of NO with CO under oxidizing conditions.
17
Rydén, Magnus. "Strategic Placing of Field Hospitals Using Spatial Analysis". Thesis, KTH, Geoinformatik och Geodesi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-34292.
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Humanitarian help organisations today may benefit on improving their location analysis when placing field hospitals in countries hit by a disasters or catastrophe. The main objective of this thesis is to develop and evaluate a spatial decision support method for strategic placing of field hospitals for two time perspectives, long term (months) and short term (weeks). Specifically, the possibility of combining existing infrastructure and satellite data is examined to derive a suitability map for placing field hospitals. Haut-Katanga in Congo is used as test area where exists a large variety of ground features and has been visited by aid organisations in the past due to epidemics and warzones. The method consists of several steps including remote sensing for estimation of population density, a Multi Criteria Evaluation (MCE) for analysis of suitability, and visualization in a webmap. The Population density is used as a parameter for an MCE operation to create a decision support map for locating field hospitals. Other related information such as road network, water source and landuse is also taken into consideration in MCE. The method can generate a thematic map that highlights the suitability value of different areas for field hospitals. By using webmap related technologies, these suitability maps are also dynamic and accessible through the Internet. This new approach using the technology of dasymetric mapping for population deprival together with an MCE process, yielded a method with the result being both a standalone population distribution and a suitability map for placing field hospitals with the population distribution taken into consideration. The use of dasymetric mapping accounted for higher resolution and the ability to derive new population distributions on demand due to changing conditions rather than using pre-existing methods with coarser resolution and a more seldom update rate. How this method can be used in other areas is also analysed. The result of the study shows that the created maps are reasonable and can be used to support the locating of field hospitals by narrowing down the available areas to be considered. The results from MCE are compared to a real field hospital scenario, and it is shown that the proposed method narrows down the localisation options and shortens the time required for planning an operation. The method is meant to be used together with other decision methods which involves non spatial factors that are beyond the scope of this thesis.
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Li, You. "Application of GIS tools in locating onshore wind power plants – A case study of Västmanland County, Sweden". Thesis, KTH, Mark- och vattenteknik (flyttat 20130630), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-171850.
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A rapid development of wind energy has been approved globally within the last few years due to the common recognition of this renewable energy technology. It is seen as one of the most promising substitutions to fossil fuels which have been exploited for over one century but were proved to be a crucial factor of human-induced climate change. However, even though wind energy has been regarded to be clean, resource saving and environmentally friendly, it still poses special problems and concerns to the surrounding social-ecological system. Thereby it requires careful selection of sites of installation. This paper provides an overview of wind energy and its development in the recent decade and focus on elaborating different issues involved in wind energy development. This is done through a case study of applying GIS tools in selecting suitable locations for onshore wind power plants in Västmanland County of Sweden.
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Moreno, Pineda Eufemio. "New f-block and mixed d,f-block molecular nanomagnets". Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/new-fblock-and-mixed-dfblock-molecular-nanomagnets(2f53085a-081b-4b27-a866-28f37f1fd633).html.
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Molecular Nanomagnets have been proposed as plausible candidates in a variety of futuristic applications. Thorough understanding of the magnetic properties of these systems is therefore necessary to develop devices that include such units. The aim of this thesis is to synthesise and structurally and magnetically characterise a range of systems that could be used as elementary units in three proposed applications such as: data storage devices, magnetic refrigerants and qubits for quantum computing. A series of mixed 3d/4f metal complexes were synthesised through solvothermal reactions and characterised by X-ray single crystal diffraction and SQUID magnetometry. Through indirect methods it was possible to obtain high magnetic entropy change for some systems. It was also possible to obtain some insight into the magnetic interactions within the systems through modelling the magnetic data. The role of the 4f-4f and 3d-4f interactions in two sets of molecules is also described. The first study is in an asymmetric dysprosium dimer, where through a range of experimental techniques and advanced theoretical methods, such ab-initio calculations we are able to explain the role of the intramolecular interactions and their effect on the SMM properties of this system. Similarly, insight into the role of the 3d-4f interactions is achieved through the observation of the magnetic behaviour of a family of 27 tetranuclear systems, though SQUID data and ab-initio calculations. Finally, chemical functionalization of a well-proposed qubits, namely {Cr7Ni} and subsequent reaction with a redox active metal ion, CoII/III, two {Cr7Ni} systems are linked. The magnitude of the exchange interaction between the {Cr7Ni}-CoII-{Cr7Ni} was determined through Electron Paramagnetic Resonance. Furthermore, by chemical oxidation/reduction of the cobalt between paramagnetic and diamagneticstates, i.e. CoII and CoIII respectively, we demonstrate that the interaction can be switched ON/OFF. This characteristic makes of these systems candidates to function as a SWAP gate.
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Hasan, Muhammad Noman. "Design, Development, Characterization, and Validation of A Paper-based Microchip Electrophoresis System". Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case157979860948204.
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Anozie, Valencia Chibuike. "Parametric Study of Friction-Damped Braced Frames with Buckling-Restrained Columns using Recommended Frame and BRC Strength Factors". University of Akron / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=akron1500294960127361.
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Li, Donghui. "MCG: A multilayer general area MCM routing algorithm". Diss., The University of Arizona, 1995. http://hdl.handle.net/10150/187524.
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A new multilayer, general-area, multichip module (MCM) routing algorithm, called MCG, is introduced. The algorithm differs from other MCM routers in the way that the routes interconnecting the nets are constructed. Some routers perform the routing net-by-net and others extend the routes piece by piece during the routing process. The MCG router takes a more global approach by constructing a small number of candidate routes for each net, building a compatibility graph for the candidate routes and reducing the graph to yield a routing solution. Due to this unique way of performing the routing, the MCG router offers several outstanding features. First, it performs the routing of the nets simultaneously. Therefore it is not subject to the net ordering problem. Second, it can give the designer the flexibility of selecting the topology of routes for the nets to be routed, which is almost impossible for other algorithms. Third, it offers a natural way to incorporate the electrical constraints into the routing process, which is absent or hard to handle in other algorithms. The timing constraint can be incorporated easily by constructing the candidate routes of the net according to the requirements of the design; and the compatibility test of the candidate routes can be used to estimate the crosstalk between the routes from different nets, which make the crosstalk estimation more sophisticated than the other techniques. Compared with other MCM routers, the MCG router produces better quality routing solutions in terms of number of layers, number of vias, total wire length and routing density. In addition to the application in the area of MCM routing, the MCG algorithm can also be applied to high density PCB routing problems.
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Cheung, Wing-hung. "A study of primary school heads’ perceptions of the new Moral and Civic Education (MCE) curriculum of 2001 and the implications for its implementation in Hong Kong". Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/9171.
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The research studies school heads’ perception of the implementation of the new Moral and Civic Education (MCE) curriculum in Hong Kong primary schools. The MCE curriculum is positioned as a key task in curriculum reform since 2001. The present study recognises school leadership role in steering curriculum delivery in which school heads’ perception is one of the determinants in shaping curriculum execution. Qualitative approach is adopted to uncover the factors affecting the perception of school heads and subsequent implementation strategies. Purposive sampling of six primary school heads is identified for interview to collect data. Content analysis is employed to make inferences from the data reviewing how school heads’ personal belief and values orientation affect the delivery of the curriculum. The MCE curriculum, resting on virtue ethics projecting desirable values to be promoted, is appealing to the school heads. The MCE curriculum designed as values education, resonates Chinese culture emphasizing cultivation of virtue through education while at the same time addressing the societal expectation of the call for promoting national identity with the return of Hong Kong to China in 1997. Given the social and political context of Hong Kong, positive attitude is exhibited by all the sample school heads but they respond differently to the curricular role, reflecting a wide spectrum of understanding of the curriculum and pedagogical competency. The research findings propose the importance of a heightened awareness of school heads’ cognition of the curriculum but their attitude towards the curriculum is deterministic how the curriculum is implemented. The attitude taken hinges on the values and belief of school heads vis a vis organisation values of the school. A model portraying school heads’ awareness, attitude and action for curriculum implementation is recommended to further study school leadership with implications for theory building and practice.
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Arone, Samuel Garicai. "Impacto de meios electrónicos de pagamento sobre as notas e moedas em circulação : o caso de Moçambique". Master's thesis, Instituto Superior de Economia e Gestão, 2014. http://hdl.handle.net/10400.5/7222.
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Mestrado em Econometria Aplicada e PrevisãoO presente estudo analisa o impacto dos instrumentos de pagamento electrónico, nomeadamente cartões (débito e crédito), volume de transaçcões em ATM e em POS, sobre a procura de notas e moedas em Moçambique, usando dados mensais de 2005M01 a 2013M12. Evidências empíricas resultantes da aplicação da abordagem Bounds Testing sugerem a existência de relação de equilíbrio de longo prazo. Nestes termos, tendo em conta a dimensão da amostra, foi privilegiado o uso do modelo ADL na forma de B ardsen para captar, simultaneamente, os efeitos de curto e longo prazos. Foram também estimadas as relações de longo prazo com recurso aos estimadores SOLS (static OLS) e DOLS (dynamic OLS), e os respectivos resíduos foram empregues na estimação dos modelos de correcção de erro em dois passos. As estimativas dos coe_cientes de ajustamento de curto prazo (para o equilíbrio) indicam que pouco mais de 20% do desequilíbrio da procura de notas e moedas, no período anterior, tende a ser corrigido no período de um mês. Adicionalmente, as estimativas das elasticidades de longo prazo revelam-se estatisticamente signi_cativas (com a excepção das do volume de transacções em POS) e com os sinais esperados. O sinal positivo das estimativas dos multiplicadores da quantidade de cartões e do volume de transacções em ATM mostra que, cartões e transacções em ATM tendem a expandir a circulação monetária, enquanto o sinal negativo das estimativas do multiplicador do volume de transacções em POS revela que pagamentos em POS tendem a ser substitutos de numerário. Quanto à dinâmica de curto prazo, somente o multiplicador do volume de transacções em ATM revela-se estatisticamente signicativo a nível de 5%. Em geral, os cartões são frequentemente mais usados para o levantamento de numerário do que para pagamentos em POS e prestação de outros serviços nas ATM.
This paper examines the impact of electronic means of payment including debit and credit cards, volume of transactions at ATM and POS on cash demand (notes and coins in circulation outside banks in Mozambique), using monthly data from 2005M01 to 2013M12. Empirical evidence resulting from the application of the Bounds Testing approach suggests the existence of a long-run equilibrium relationship. Accordingly, taking into account the sample size, the B ardsen ADL based form model was privileged to capture simultaneously short and long run e_ects. The long-run relationship was also estimated using the SOLS (static OLS) and DOLS (dynamic OLS) estimators. Then, the residues of these models were used to estimate error correction models in two steps. Overall, the estimates of the coe_cients of short-run adjustment indicate that just over 20% of the imbalances on cash demand in the previous period are restated within one month. Moreover, the long-run elasticities prove statistically signi_cant (except whose of the volume of transactions at POS) with expected signs. The positive sign of the multiplier estimates of cards as well as of the volume of ATM transactions suggests that card and ATM transactions compliment cash, while the negative sign of the multiplier estimates of the volume of transactions at POS reveal that POS payments tend to substitute it. Relating to short-run dynamics, statistical evidence only supported the positive sign impact on ATM transaction volume multiplier at the level of 5%. In general, cards are often used primarily for accessing cash than for payments at POS and others facilities at ATM.
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Setegn, Shimelis Gebriye. "Modelling Hydrological and Hydrodynamic Processes in Lake Tana Basin, Ethiopia". Doctoral thesis, KTH, Vattendragsteknik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12024.
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Lake Tana Basin is of significant importance to Ethiopia concerning water resources aspects and the ecological balance of the area. The growing high demands in utilizing the high potentials of water resource of the Lake to its maximal limit, pictures a disturbing future for the Lake. The objective of this study was to assess the influence of topography, soil, land use and climatic varia-bility on the hydrological and hydrodynamic processes of the Lake Tana Basin. The physically based SWAT model was successfully calibrated and validated for flow and sediment yield. Se-quential uncertainty fitting (SUFI-2), parameter solution (ParaSol) and generalized likelihood un-certainty estimation (GLUE) calibration and uncertainty analysis methods were compared and used for the set-up of the SWAT model. There is a good agreement between the measured and simulated flows and sediment yields. SWAT and GIS based decision support system that uses multi-criteria evaluation (MCE) was used to identify the most vulnerable areas to soil erosion in the basin. The results indicated that 12 to 30.5% of the watershed is high erosion potential. Pro-jected changes in precipitation and temperature in the basin for two seasons were analyzed using outputs from fifteen global climate models (GCMs). A historical-modification procedure was used to downscale large scale outputs from GCM models to watershed-scale climate data. The results showed significant changes in streamflow and other hydrological parameters in the period between 2045-2100. SWAT was combined with a three dimensional hydrodynamic model, GEMSS to investigate the flow structure, stratification, the flushing time, lake water balance and finally the Lake‘s water level response to planned water removal. We have found an alarming and dramatic fall of the water levels in Lake Tana as response to the planned water withdrawal. The combination of the two models can be used as a decision support tools to better understand and manage land and water resources in watersheds and waterbodies. The study showed that the Lake Tana Basin may experience a negative change in water balance in the forthcoming decades due to climate change as well as over abstraction of water resources.QC 20100720
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Hong, James S. "Rat umbilical cord derived stromal cells maintain markers of pluripotency : Oct4, Nanog, Sox2, and alkaline phosphatase in mouse embryonic stem cells in the absence of LIF and 2-MCE". Thesis, Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/2326.
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Quader, Abdul. "MARTENSITIC PHASE TRANSFORMATION IN NI-MN-GA BASED HEUSLER ALLOYS". Miami University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1501240663677547.
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Liakos, Panagiotis. "Expression des récepteurs mélanocortines MC5 et MC2 dans le cortex surrénal". Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10100.
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Recemment le clonage de la famille des recepteurs melanocortine (mc-r) a mis en evidence cinq recepteurs melanocortines distincts couples aux proteines g et a l'adenylate cyclase. Le recepteur mc2 correspond au recepteur acth du cortex surrenal et lie uniquement l'acth. Le recepteur mc5 (mc5-r) presente une expression large, il est detecte egalement dans le cortex surrenal, et lie l'acth et l'a-msh. Au cours de ce travail, l'expression du mc5-r et du mc2-r dans les differentes zones du cortex surrenal bovin a ete etudiee. Le mc5-r est detecte uniquement dans la zone glomerulee bovine. Le mc2-r est observe dans les deux zones et ses arnm sont plus abondants dans la zone glomerulee. L'analyse de l'expression du mc5-r montre que l'acth, l'a-msh et l'all stimulent les arnm du mc5-r dans les cellules glomerulees et les arnm du mc5-r sont alors detectes dans les cellules fasciculees. Tgfb1 bloque l'expression des arnm du mc5-r induite par l'acth dans les cellules glomerulees. Le role du mc5-r dans le cortex surrenal n'est pas connu. Une premiere approche suggere que le mc5-r pourrait participer a la production d'aldosterone des cellules glomerulees. Chez le rat nouveau-ne, son expression suggere un role potentiel dans les temps precoces du developpement postnatal de la glande. Nous observons egalement une surexpression des arnm du mc5-r dans les cas d'aldosteronomes de la surrenale laissant envisager sa participation dans ces tumeurs de la surrenale comme le mc2-r.
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Wang, Xuechuan, i n/a. "Feature Extraction and Dimensionality Reduction in Pattern Recognition and Their Application in Speech Recognition". Griffith University. School of Microelectronic Engineering, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030619.162803.
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Conventional pattern recognition systems have two components: feature analysis and pattern classification. Feature analysis is achieved in two steps: parameter extraction step and feature extraction step. In the parameter extraction step, information relevant for pattern classification is extracted from the input data in the form of parameter vector. In the feature extraction step, the parameter vector is transformed to a feature vector. Feature extraction can be conducted independently or jointly with either parameter extraction or classification. Linear Discriminant Analysis (LDA) and Principal Component Analysis (PCA) are the two popular independent feature extraction algorithms. Both of them extract features by projecting the parameter vectors into a new feature space through a linear transformation matrix. But they optimize the transformation matrix with different intentions. PCA optimizes the transformation matrix by finding the largest variations in the original feature space. LDA pursues the largest ratio of between-class variation and within-class variation when projecting the original feature space to a subspace. The drawback of independent feature extraction algorithms is that their optimization criteria are different from the classifiers minimum classification error criterion, which may cause inconsistency between feature extraction and the classification stages of a pattern recognizer and consequently, degrade the performance of classifiers. A direct way to overcome this problem is to conduct feature extraction and classification jointly with a consistent criterion. Minimum classification Error (MCE) training algorithm provides such an integrated framework. MCE algorithm was first proposed for optimizing classifiers. It is a type of discriminative learning algorithm but achieves minimum classification error directly. The flexibility of the framework of MCE algorithm makes it convenient to conduct feature extraction and classification jointly. Conventional feature extraction and pattern classification algorithms, LDA, PCA, MCE training algorithm, minimum distance classifier, likelihood classifier and Bayesian classifier, are linear algorithms. The advantage of linear algorithms is their simplicity and ability to reduce feature dimensionalities. However, they have the limitation that the decision boundaries generated are linear and have little computational flexibility. SVM is a recently developed integrated pattern classification algorithm with non-linear formulation. It is based on the idea that the classification that a.ords dot-products can be computed efficiently in higher dimensional feature spaces. The classes which are not linearly separable in the original parametric space can be linearly separated in the higher dimensional feature space. Because of this, SVM has the advantage that it can handle the classes with complex nonlinear decision boundaries. However, SVM is a highly integrated and closed pattern classification system. It is very difficult to adopt feature extraction into SVMs framework. Thus SVM is unable to conduct feature extraction tasks. This thesis investigates LDA and PCA for feature extraction and dimensionality reduction and proposes the application of MCE training algorithms for joint feature extraction and classification tasks. A generalized MCE (GMCE) training algorithm is proposed to mend the shortcomings of the MCE training algorithms in joint feature and classification tasks. SVM, as a non-linear pattern classification system is also investigated in this thesis. A reduced-dimensional SVM (RDSVM) is proposed to enable SVM to conduct feature extraction and classification jointly. All of the investigated and proposed algorithms are tested and compared firstly on a number of small databases, such as Deterding Vowels Database, Fishers IRIS database and Germans GLASS database. Then they are tested in a large-scale speech recognition experiment based on TIMIT database.
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Wang, Xuechuan. "Feature Extraction and Dimensionality Reduction in Pattern Recognition and Their Application in Speech Recognition". Thesis, Griffith University, 2003. http://hdl.handle.net/10072/365680.
Pełny tekst źródłaStreszczenie:
Conventional pattern recognition systems have two components: feature analysis and pattern classification. Feature analysis is achieved in two steps: parameter extraction step and feature extraction step. In the parameter extraction step, information relevant for pattern classification is extracted from the input data in the form of parameter vector. In the feature extraction step, the parameter vector is transformed to a feature vector. Feature extraction can be conducted independently or jointly with either parameter extraction or classification. Linear Discriminant Analysis (LDA) and Principal Component Analysis (PCA) are the two popular independent feature extraction algorithms. Both of them extract features by projecting the parameter vectors into a new feature space through a linear transformation matrix. But they optimize the transformation matrix with different intentions. PCA optimizes the transformation matrix by finding the largest variations in the original feature space. LDA pursues the largest ratio of between-class variation and within-class variation when projecting the original feature space to a subspace. The drawback of independent feature extraction algorithms is that their optimization criteria are different from the classifier’s minimum classification error criterion, which may cause inconsistency between feature extraction and the classification stages of a pattern recognizer and consequently, degrade the performance of classifiers. A direct way to overcome this problem is to conduct feature extraction and classification jointly with a consistent criterion. Minimum classification Error (MCE) training algorithm provides such an integrated framework. MCE algorithm was first proposed for optimizing classifiers. It is a type of discriminative learning algorithm but achieves minimum classification error directly. The flexibility of the framework of MCE algorithm makes it convenient to conduct feature extraction and classification jointly. Conventional feature extraction and pattern classification algorithms, LDA, PCA, MCE training algorithm, minimum distance classifier, likelihood classifier and Bayesian classifier, are linear algorithms. The advantage of linear algorithms is their simplicity and ability to reduce feature dimensionalities. However, they have the limitation that the decision boundaries generated are linear and have little computational flexibility. SVM is a recently developed integrated pattern classification algorithm with non-linear formulation. It is based on the idea that the classification that a.ords dot-products can be computed efficiently in higher dimensional feature spaces. The classes which are not linearly separable in the original parametric space can be linearly separated in the higher dimensional feature space. Because of this, SVM has the advantage that it can handle the classes with complex nonlinear decision boundaries. However, SVM is a highly integrated and closed pattern classification system. It is very difficult to adopt feature extraction into SVM’s framework. Thus SVM is unable to conduct feature extraction tasks. This thesis investigates LDA and PCA for feature extraction and dimensionality reduction and proposes the application of MCE training algorithms for joint feature extraction and classification tasks. A generalized MCE (GMCE) training algorithm is proposed to mend the shortcomings of the MCE training algorithms in joint feature and classification tasks. SVM, as a non-linear pattern classification system is also investigated in this thesis. A reduced-dimensional SVM (RDSVM) is proposed to enable SVM to conduct feature extraction and classification jointly. All of the investigated and proposed algorithms are tested and compared firstly on a number of small databases, such as Deterding Vowels Database, Fisher’s IRIS database and German’s GLASS database. Then they are tested in a large-scale speech recognition experiment based on TIMIT database.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Microelectronic Engineering
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Setegn, Shimelis Gebriye. "Hydrological and sediment Yield modelling in Lake Tana Basin, Blue Nile Ethiopia". Licentiate thesis, Stockholm : Mark- och vattenteknik, Land and Water Resource Engineering, Kungliga Tekniska högskolan, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4796.
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Olša, Petr. "Návrh řízení všesměrového mobilního robotu O3-X". Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-229210.
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This thesis deals with the design of a three-wheeled omni-directional robot control. The model of control is designed for robot´s omni-directional platform driven by maxon motor with the intelligent positioning controller EPOS. The design of control contains: - installation of the coordinated systems and transformation from one of them into another - design of system´s kinematical model - creation of classes for control and communication with EPOS - creation of the simulative program - planning of the mobile robot´s path - verification that the system is working The solution was based on continuous accelerated motion and the maximal acceleration of wheels was concerned, so that the slip would be suppressed. The function of the model was partly verified.
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Yang, Hocheol. "ONLINE NEWS AND THE EFFECTS OF HEURISTIC CUES ON AUDIENCES' ATTITUDES". Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1399649731.
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Albertazzi, Davide. "Utilizzo degli esercizi di stabilizzazione del core per il miglioramento della sintomatologia dolorosa nei soggetti con chronic non-specific low back pain: revisione basata sulle evidenze". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
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Obiettivo: Confrontare gli esercizi di stabilizzazione del core con esercizi generici e globali per la gestione della sintomatologia dolorosa e della disabilità a breve, medio e lungo termine, nei soggetti con chronic non-specific LBP.
Contesto: Il Low Back Pain (LBP) è un disordine multifattoriale ad alta prevalenza. L’intervento più comune in questi casi è quello conservativo fisioterapico. Dopo le ricerche sull’instabilità lombare condotte da Panjabi e colleghi si è sviluppato il concetto di core stability. Negli anni, molti clinici hanno adottato questa pratica rendendola famosa ma in letteratura non si è ancora giunti alla conclusione di quale sia l’approccio più adatto al trattamento del LBP.
Materiali e metodi: La ricerca è stata condotta su PubMed, Cochrane Library e PEDro tra febbraio 2019 e agosto 2019. Sono state incluse solo revisioni sistematiche con meta-analisi, pubblicate negli ultimi 10 anni e che confrontassero esercizi di stabilizzazione del core ed esercizi generici nel miglioramento di dolore e disabilità a breve, medio e lungo termine, in soggetti con LBP cronico e aspecifico.
Risultati: Nel follow-up a breve termine tutte e 4 le meta-analisi hanno trovato differenze statisticamente significative a favore degli esercizi di stabilizzazione del core rispetto ad esercizi generici nel miglioramento del dolore e della disabilità. Nel follow-up a medio termine solamente 2 dei 4 studi trovano differenze significative a favore del primo gruppo. Nel follow-up a lungo termine non sono state registrate differenze statisticamente significative tra i due approcci per il miglioramento del dolore mentre solo uno studio trova differenze statisticamente significative circa la disabilità.
Conclusioni: Una differenza statisticamente significativa ha favorito gli esercizi di stabilizzazione del core rispetto ad esercizi generici nel diminuire dolore e disabilità a breve termine. Tuttavia, nessuna differenza significativa è stata osservata a lungo termine.
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Akhbari, Pouria. "Analysis of cellular transcriptomic changes induced by Merkel cell polyomavirus miRNA". Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/15902.
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Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with rising global incidence. Merkel cell polyomavirus (MCV) was discovered in 2008 in 80% of MCC samples and since then a causal link between MCV and the majority of MCC cases has been established. microRNAs (miRNA, miR) are a family of small non-coding RNAs which play a key role in post-transcriptional regulation of gene expression and are considered significant players in disease and development in many species. Whilst the focus of MCV research has thus far been on the oncogenic MCV early proteins, large tumour (LT) and small tumour (sT) antigens, there is a knowledge gap regarding MCV miRNA and its functional significance in MCV pathogenesis. Given the emerging importance of viral miRNAs in virus-host interaction and pathogenesis, the aim of this doctoral research project was to investigate alterations in host cell transcripts induced by MCV miRNA and determine any functional significance these might have on virus-host cell interaction. RNA sequencing (RNA-Seq) in the presence and absence of MCV miRNA uncovered a multitude of downregulated cellular transcripts. Gene ontology analysis revealed that MCV miRNA targets transcripts associated with multiple cellular processes, however, regulation of immune response was overrepresented in our datasets. Validation of RNA-Seq data using MCV miRNA mimics and a synthetic, fully replicative MCV genome (MCVSyn) confirmed RNA-Seq data at mRNA and protein expression level for several targets, including the cytokine stimulating gene, SP100, and the neutrophil stimulator chemokine, CXCL8. Moreover, dual luciferase assays revealed that SP100 and MAPK10 (a member of mitogen-activated protein kinases (MAPK) family which is involved in regulation of CXCL8 expression) are directly and specifically targeted and downregulated by MCV miRNA. The MCV miRNA-dependent dysregulation of CXCL8 secretion is associated with impaired neutrophil migration, suggesting that the virus miRNA may be implicated in evasion of the host immune response.
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Doherty, Rachel Veronica Mary. "Interaction of α-melanocyte stimulating hormone and its analogues with the human melanocortin receptor subtypes, MC1-R and MC4-R". Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321820.
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Chinenyeze, Samuel Jaachimma. "Mango : a model-driven approach to engineering green Mobile Cloud Applications". Thesis, Edinburgh Napier University, 2017. http://researchrepository.napier.ac.uk/Output/976572.
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With the resource constrained nature of mobile devices and the resource abundant offerings of the cloud, several promising optimisation techniques have been proposed by the green computing research community. Prominent techniques and unique methods have been developed to offload resource/computation intensive tasks from mobile devices to the cloud. Most of the existing offloading techniques can only be applied to legacy mobile applications as they are motivated by existing systems. Consequently, they are realised with custom runtimes which incur overhead on the application. Moreover, existing approaches which can be applied to the software development phase, are difficult to implement (based on manual process) and also fall short of overall (mobile to cloud) efficiency in software qualityattributes or awareness of full-tier (mobile to cloud) implications. To address the above issues, the thesis proposes a model-driven architecturefor integration of software quality with green optimisation in Mobile Cloud Applications (MCAs), abbreviated as Mango architecture. The core aim of the architecture is to present an approach which easily integrates software quality attributes (SQAs) with the green optimisation objective of Mobile Cloud Computing (MCC). Also, as MCA is an application domain which spans through the mobile and cloud tiers; the Mango architecture, therefore, takesinto account the specification of SQAs across the mobile and cloud tiers, for overall efficiency. Furthermore, as a model-driven architecture, models can be built for computation intensive tasks and their SQAs, which in turn drives the development – for development efficiency. Thus, a modelling framework (called Mosaic) and a full-tier test framework (called Beftigre) were proposed to automate the architecture derivation and demonstrate the efficiency of Mango approach. By use of real world scenarios/applications, Mango has been demonstrated to enhance the MCA development process while achieving overall efficiency in terms of SQAs (including mobile performance and energy usage compared to existing counterparts).
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Schmid, Christian, i Yigal Gerchak. "How should a principal reward and support agents when firm performance is characterized by success or failure?" John Wiley & Sons, Ltd, 2019. http://dx.doi.org/10.1002/mde.3006.
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Principal-agent models with multiple agents typically assume that the principal wishes to
maximize the sum of the agents' achievements (net of the rewards paid to them). But in many
settings, like R&D, all that the principal "Needs" is that at least one agent will be "successful." We
identify settings where the principal actually wants agents to refrain from exerting high effort
in order to save expected compensation. We show that the number of agents can decrease in
the project's value for the principal. We also consider sequential efforts and investigate settings
where the principal can provide support to agents.
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Brenner, Mark R. "GaP/Si Heteroepitaxy (Suppression of Nucleation Related Defects)". The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1253216057.
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Brunton, Adam North. "MCP optics". Thesis, University of Leicester, 1994. http://hdl.handle.net/2381/35847.
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This thesis is an account of research into a novel type of X-ray optic - the microchannel plate (MCP). Experiments to determine the point to point focusing properties of square pore MCPs manufactured by Galileo Electro-Optics and Philips Photonics are reported. These were performed both in a test chamber at Leicester with an electron-bombardment X-ray source and with a laser-plasma X-ray source at the Rutherford Appleton Laboratory. A resolution of 6 arcmin and an intensity gain of 20 were recorded using a Galileo focusing MCP. An invesigation into the focusing action of MCPs which have been curved to a spherical figure is detailed. Such curved MCPs may, in a manner reminiscent of a conventional refractive lens, be used to focus a parallel X-ray beam to a point forming the basis of an X-ray telescope, or conversely to convert the diverging beam from a point-like X-ray source to a quasi-parallel one. The curving experiments were performed by Philips Photonics on standard circular pore MCPs. Tests on these plates were performed at Leicester; the results appear favourable. The technique has been applied to MCPs of up to 4mm thickness, curving them to a radius of 1.4m (0.7m focal length). A comprehensive Monte Carlo ray-tracing model is presented. This was initially developed to facilitate an understanding of the geometry of MCP focusing and to produce idealised images corresponding to a given experimental set up. These perfect images may be compared with, or used to predict experimental results. Comparison with experimental results led to incorporation of MCP distortions into the code. These distortions have been found by a programme of metrology which is also described. The model has led to a clear insight into the causes of poor image quality and their relative importance.
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Moore, Gabrielle. "Magic Mae". Kent State University Honors College / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1525191279688537.
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Walid, Abdelrahman. "4G LTE : eMBMS with MBSFN Service Simulation using OPNET". Thesis, Mittuniversitetet, Avdelningen för informations- och kommunikationssystem, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-24208.
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Long Term Evolution (LTE) known in the market as 4G LTE, it is an evolution of the GSM/UMTS standard. The overall aim of LTE was to provide a new radio access technology focusing on packet-switched data only. LTE has provided a new peak download rates, low data transfer latencies, and improved the support for mobility. 3Th Generation Partnership Project (3GPP) specialized that LTE released 10 and beyond known as LTE-advanced it is the second evolution of LTE. It has some services such as Coordinated Multipoint Transmission and Reception (CoMP), evolved Multimedia Broadcast and Multicast Service (eMBMS) with Multicast-Broadcast Single-Frequency Network (MBSFN). The development still continuous on LTE-advanced, it is intended to meet the requirement of advanced application that will become common in the wireless marketplace in future. The goals of this project is to simulate one of LTE-A services on LTE standard such as CoMP or/and eMBMS with MBSFN using OPENT LTE, and measure some statistic such as spectral efficiency and also some other statistics, describe centralization vs. decentralization in LTE, and synchronization in the base station in LTE. OPNET LTE support eMBMS with MBSFN, and don’t support CoMP, the simulation has been done by using eMBMS with MBSFN. Finally the objectives of the project has achieved, the result show that when eMBMS with MBSFN is implemented the throughput increased in the downlink to about 5.52 Mbps and in the uplink to about 5.18 Mbps, and also the system spectral efficiency increased in eNB1 from about 10.25 (bits/s/Hz/cell) to about 13.75 (bits/s/Hz/cell) and in eNB2 from about 10.25 (bits/s/Hz/cell) to about 17.25 (bits/s/Hz/cell). The project also answers if it is possible to have centralization in LTE, describe synchronization in the base station in LTE, and if OPNET is useful for big research.
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Grand, Natacha. "Caractérisation fonctionnelle du système MCH/MCH-R1 dans des modèles neuronaux et immunitaires : de nouveaux rôles pour la MCH ?" Nice, 2006. http://www.theses.fr/2006NICE4051.
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La « Melanin-Concentrating Hormone » (MCH) est un neuropeptide cyclique de 19 acides aminés chez les mammifères, principalement exprimé au niveau de l’hypothalamus, où il est impliqué dans plusieurs fonctions comme la régulation de la prise alimentaire ou l’homéostasie énergétique. La MCH est également présente dans de nombreux organes périphériques comme le thymus, la rate ou l’intestin. Deux récepteurs à la MCH, nommés MCH-R1 et MCH-R2, ont été clonés. La majorité des effets connus de la MCH semble être médiés par le MCH-R1. Dans la première partie de mes travaux, nous avons caractérisé les voies de transduction et les effets cellulaires observés après l’activation du récepteur MCH-R1 dans des modèles neuronaux. Ainsi, dans des lignées de neuroblastomes humains, les cellules SH-SY5Y, nous avons pu montrer qu’après traitement par la MCH, seule la voie des MAPK est activée par phosphorylation de Erk1/2, conduisant de manière sélective à une différenciation neuronale. De plus, nous avons montré par des études de puces à ADN et de PCR quantitative que cette pousse neuritique est associée à l’activation d’une vingtaine de gènes dont certains sont impliqués dans la différenciation cellulaire. Nous avons ainsi mis en évidence un rôle potentiel du système MCH/ MCH-R1 dans la différenciation des neuroblastomes, exprimant le récepteur de façon endogèneDans un second temps, nous avons entrepris l’étude de la MCH et de son récepteur dans un organe lymphoïde primaire : le thymus. Nous avons tout d’abord mis en évidence la présence de MCH dans les cellules épithéliales médullaires du thymus et de son récepteur MCH-R1 dans les thymocytes double négatif (DN), simple positif CD4 et CD8. Des études ex-vivo utilisant les souris invalidées pour le récepteur ont montré que la MCH et son récepteur peuvent être impliqués dans la maturation des thymocytes de souris, notamment en agissant au niveau des stades DN2 et DN3. Des études in vivo de transfert de moelle ont confirmé un potentiel rôle du système MCH dans la différenciation thymocytaire. Ces résultats ont permis de mettre en évidence un rôle de la MCH dans la différenciation des lymphocytes au sein du thymus de souris
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Wang, Chao. "MBE-grown spintronic materials". Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515009.
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Tarigopula, Sriteja. "MBE Growth and Instrumentation". Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5243/.
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This thesis mainly aims at application of principles of engineering technology in the field of molecular beam epitaxy (MBE). MBE is a versatile technique for growing epitaxial thin films of semiconductors and metals by impinging molecular beams of atoms onto a heated substrate under ultra-high vacuum (UHV) conditions. Here, a LabVIEW® (laboratory virtual instrument engineering workbench) software (National Instruments Corp., http://www.ni.com/legal/termsofuse/unitedstates/usH) program is developed that would form the basis of a real-time control system that would transform MBE into a true-production technology. Growth conditions can be monitored in real-time with the help of reflection high energy electron diffraction (RHEED) technique. The period of one RHEED oscillation corresponds exactly to the growth of one monolayer of atoms of the semiconductor material. The PCI-1409 frame grabber card supplied by National Instruments is used in conjunction with the LabVIEW software to capture the RHEED images and capture the intensity of RHEED oscillations. The intensity values are written to a text file and plotted in the form of a graph. A fast Fourier transform of these oscillations gives the growth rate of the epi-wafer being grown. All the data being captured by the LabVIEW program can be saved to file forming a growth pedigree for future use. Unattended automation can be achieved by designing a control system that monitors the growth in real-time and compares it with the data recorded from the LabVIEW program from the previous growth and adjusts the growth parameters automatically thereby growing accurate device structures.
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Požár, Marek. "Laboratorní zdroj řízený MCU". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-219109.
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Laboratory source is basic and necessary part of almost every modern electronics laboratories. Development cannot be done without good laboratory resources. It is main function is supply stabilized DC voltage and current. It appears in a simpler version without the continuous regulation of voltage and current, with only predetermined switching voltage. Of course there are also more demanding applications, where stable voltage adjustable fluently and where is continuous of stable voltage for example LCD applications. This term project deals with a connection of microprocessor and stabilizing and regulating circuits for voltage and current of laboratory sources output. That microprocessor controls performance features by DA converter, which provide a stable output voltage which required power.
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Taouli, Abderrahim [Verfasser]. "Aciditäts- und Adsorptionsuntersuchungen an mesoporösen MCM-41- und MCM-48-Materialien / Abderrahim Taouli". Aachen : Shaker, 2003. http://d-nb.info/1172613982/34.
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Bennani, Yacine. "Signature Électromagnétique Bistatique d'une cible complexe intégrée dans son environnement. Application à l'imagerie ISAR d'une scène maritime". Phd thesis, Université de Bretagne occidentale - Brest, 2012. http://tel.archives-ouvertes.fr/tel-00839370.
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Le travail réalisé dans le cadre de cette thèse s'intègre dans le domaine de la télédétection de l'environnement maritime. Il porte, d'une part sur l'étude de l'interaction d'une onde électromagnétique avec une surface maritime en présence d'une cible complexe et observée en configuration bistatique. D'autre part, le travail est complété par l'étude et l'analyse de l'influence sur cette interaction des différents paramètres à la fois liés à la cible et à l'environnement. Dans ce contexte d'étude, le présent travail s'articule autour de deux volets importants. Le premier vise l'étude et la simulation de la Surface Equivalente Radar (SER) d'une cible complexe placée dans un environnement marin. Et un deuxième volet applicatif qui traite l'imagerie radar ISAR d'une cible complexe. Afin de traiter le premier point, le modèle électromagnétique retenu est basé sur une combinaison de méthodes asymptotiques (Optique Physique (OP), Optique Géométrique (OG), Méthode des courants équivalents (MCE)) intégrant les phénomènes d'ombrage et les multitrajets. Afin d'introduire l'influence de la surface de mer sur la réponse électromagnétique de la cible dans son environnement, nous avons opté pour une représentation de la scène (cible+surface de mer) par un ensemble de facettes triangulaires. Dans ce cadre, la cible discrétisée par un maillage triangulaire est générée à l'aide d'un outil de CAO (CATIA V5), quant à la surface de la mer, elle est générée en utilisant le spectre de mer d'Elfouhaily (et le modèle de Debye pour la prise en compte des paramètres diélectriques de l'eau de mer). Enfin, afin d'appliquer la méthode développée dans le cadre de l'imagerie radar ISAR, le calcul de la SER de la cible navale a été effectué en considérant une nouvelle représentation de la cible en parallélépipèdes. La méthodologie proposée a été évaluée via des simulations ainsi que des expérimentations (dans la chambre anéchoïque de l'ENSTA Bretagne) sur un modèle générique d'un navire.
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Bandyopadhyay, Mahuya. "Synthesis of mesoporous MCM-48 with nanodispersed metal and metal oxide particles inside the pore system". [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=974056669.
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Neumann, Lena. "Anfangsstadien des ionenstrahlgestützten epitaktischen Wachstums von Galliumnitrid-Schichten auf Siliziumkarbid". Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-124073.
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Im Mittelpunkt der vorliegenden Arbeit steht die Herstellung ultradünner epitaktischer Galliumnitrid-Schichten auf einem Siliziumkarbid-Substrat mit dem Verfahren der ionenstrahlgestützten Molekularstrahlepitaxie. Für die Analyse der Oberflächentopographie der Galliumnitrid-Schichten direkt nach der Abscheidung – ohne Unterbrechung der Ultrahochvakuum-Bedingungen – wurde ein Rastersondenmikroskop in die Anlage integriert. Als weitere Hauptanalysenmethode wurde die Reflexionsbeugung hochenergetischer Elektronen zur Bestimmung der Oberflächenstrukturen in situ während der Schichtabscheidung eingesetzt. Weiterhin wurden die Galliumnitrid-Schichten hinsichtlich ihrer strukturellen Eigenschaften mittels Röntgenstrahl-Diffraktometrie, Röntgen-Photoelektronenspektroskopie und Transmissionselektronenmikroskopie ex situ charakterisiert.
Wesentliches Ziel dieser Arbeit war die Herausstellung des Einflusses maßgeblicher Abscheidungsparameter (vor allem Substrattemperatur und Gallium-Depositionsrate) auf die Schichteigenschaften sowie die Optimierung dieser Wachstumsparameter. Besonderes Augenmerk lag auf der Untersuchung der Auswirkungen des Stickstoffion-zu-Galliumatom-Verhältnisses und des Einflusses der niederenergetischen Ionenbestrahlung auf das Galliumnitrid-Schichtwachstum im Frühstadium. Dies betrifft hauptsächlich den Wachstumsmodus (zwei- oder dreidimensional) und die Bildung der hexagonalen oder der kubischen Phase.